ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0429 good L KOG4141 Replication, recombination and repair DNA repair and recombination protein RAD52/RAD22
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0429 142413 143720 436
(436 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YML032c [L] KOG4141 DNA repair and recombination protein RAD52/R... 409 e-114
SPAC30D11.10 [L] KOG4141 DNA repair and recombination protein RA... 194 2e-49
ECU09g0930 [L] KOG4141 DNA repair and recombination protein RAD5... 180 4e-45
SPBC119.14 [L] KOG4141 DNA repair and recombination protein RAD5... 170 3e-42
Hs20143952 [L] KOG4141 DNA repair and recombination protein RAD5... 160 3e-39
Hs20143958 [L] KOG4141 DNA repair and recombination protein RAD5... 130 5e-30
Hs20143956 [L] KOG4141 DNA repair and recombination protein RAD5... 85 2e-16
Hs20143954 [L] KOG4141 DNA repair and recombination protein RAD5... 63 8e-10
YDL059c [L] KOG4141 DNA repair and recombination protein RAD52/R... 52 2e-06
>YML032c [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 504
Score = 409 bits (1052), Expect = e-114
Identities = 219/381 (57%), Positives = 258/381 (67%), Gaps = 12/381 (3%)
Query: 9 NGKDDIQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEVKNVTI 68
N +DIQTKLDKKLGPEYISKRVGFG+SR+AYIEGW+ INLANQIFGY+GWSTEVK+V I
Sbjct: 49 NHSEDIQTKLDKKLGPEYISKRVGFGTSRIAYIEGWRVINLANQIFGYNGWSTEVKSVVI 108
Query: 69 DFLDERQGRFSIGCTAIVRVSLADGTFREDIGYGTVENERRKASAFERAKKSAVTDALKR 128
DFLDERQG+FSIGCTAIVRV+L GT+REDIGYGTVENERRK +AFERAKKSAVTDALKR
Sbjct: 109 DFLDERQGKFSIGCTAIVRVTLTSGTYREDIGYGTVENERRKPAAFERAKKSAVTDALKR 168
Query: 129 SLRGFGNALGNCLYDKDFLAKIDKVKFDPPDFDEGNLFRPADELSEMSRSNMVGDAHTEG 188
SLRGFGNALGNCLYDKDFLAKIDKVKFDPPDFDE NLFRP DE+SE SR+N + + +
Sbjct: 169 SLRGFGNALGNCLYDKDFLAKIDKVKFDPPDFDENNLFRPTDEISESSRTNTLHENQEQQ 228
Query: 189 PSLKKRSLTNEDRNAVPSAPAQQTYRSNNHTTQKRAPKAQAVTASASPNEETSNXXXXXX 248
KR + N P + N T + P A + S N +
Sbjct: 229 QYPNKRRQLTKVTNTNPDSTKNLVKIEN--TVSRGTPMMAAPAEANSKNSSNKDTDLKSL 286
Query: 249 XXX--------XXSFMFSDEIQDDDLLNMXXXXXXXXXXXXXXXXXXISDEATG--IISP 298
S MFSD+ QDDDL+NM S A+
Sbjct: 287 DASKQDQDDLLDDSLMFSDDFQDDDLINMGNTNSNVLTTEKDPVVAKQSPTASSNPEAEQ 346
Query: 299 VTFVTAKAATSLQHKDPIPSGSMFDPKFQAQSIRHTVDQSVSTPVRATILKEKGLDSDRS 358
+TFVTAKAATS+Q++ I S+FDPK+QAQSIRHTVDQ+ S + A++LK+K + + R
Sbjct: 347 ITFVTAKAATSVQNERYIGEESIFDPKYQAQSIRHTVDQTTSKHIPASVLKDKTMTTARD 406
Query: 359 SIYSKFAPKGKELSGTTTNSE 379
S+Y KFAPKGK+LS + E
Sbjct: 407 SVYEKFAPKGKQLSMKNNDKE 427
>SPAC30D11.10 [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 469
Score = 194 bits (494), Expect = 2e-49
Identities = 125/365 (34%), Positives = 186/365 (50%), Gaps = 35/365 (9%)
Query: 14 IQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEVKNVTIDFLDE 73
+Q+ L +KLGPEY+S+R G G V+YIE WKAI LAN+IFG++GWS+ ++++ +DF+DE
Sbjct: 29 LQSSLTRKLGPEYVSRRSGPGGFSVSYIESWKAIELANEIFGFNGWSSSIRSINVDFMDE 88
Query: 74 RQ--GRFSIGCTAIVRVSLADGTFREDIGYGTVENERRKASAFERAKKSAVTDALKRSLR 131
+ GR S+G + IVRV++ DG + EDIGYG+++N R KASAFE+ KK TDALKR+LR
Sbjct: 89 NKENGRISLGLSVIVRVTIKDGAYHEDIGYGSIDNCRGKASAFEKCKKEGTTDALKRALR 148
Query: 132 GFGNALGNCLYDKDFLAKIDKVKFDPPDFDEGNLFR---PADELSEMSRSNMVGDAHTEG 188
FGN+LGNC+YDK +L ++ K+K FD G+LFR PA S + + + T
Sbjct: 149 NFGNSLGNCMYDKYYLREVGKMKPPTYHFDSGDLFRKTDPAARESFIKKQKTLNSTRT-- 206
Query: 189 PSLKKRSLTNEDRNAVPSAPA----QQTYRSNNHTTQK------------RAPKAQAVTA 232
+ + L N+ P A +QT + ++ A+
Sbjct: 207 --VNNQPLVNKGEQLAPRRAAELNDEQTREIEMYADEELDNIFVEDDIIAHLAVAEDTAH 264
Query: 233 SASPNEETSNXXXXXXXXXXXSFMFSDEIQDDDLL------NMXXXXXXXXXXXXXXXXX 286
A+ N + S + +Q N
Sbjct: 265 PAANNHHSEKAGTQINNKDKGSHNSAKPVQRSHTYPVAVPQNTSDSVGNAVTDTSPKTLF 324
Query: 287 XISDEATGIISPVTFVTAKAATSLQHKDPIPSGSMFDPKFQAQSIRHT--VDQSVSTPV- 343
TG SP F++A+AA + + P + F+P+ + SIR T +D S S PV
Sbjct: 325 DPLKPNTGTPSP-KFISARAAAAAEGVVSAPFTNNFNPRLDSPSIRKTSIIDHSKSLPVQ 383
Query: 344 RATIL 348
RA++L
Sbjct: 384 RASVL 388
>ECU09g0930 [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 204
Score = 180 bits (456), Expect = 4e-45
Identities = 83/171 (48%), Positives = 124/171 (71%), Gaps = 1/171 (0%)
Query: 7 GKNGKDDIQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEVKNV 66
GK I L +KLGPE+IS R GF S++AY+EGW I+LAN+IFG++GWS+E++++
Sbjct: 15 GKKRTRKISKLLSQKLGPEFISYRPGFNMSKIAYVEGWTIISLANRIFGFNGWSSEIRSM 74
Query: 67 TIDFLDERQGRFSIGCTAIVRVSLADGTFREDIGYGTVENERRKASAFERAKKSAVTDAL 126
+ID+ + R +G + +VRV+L DGT+REDIG+G+ EN++ +A A+E+AKK A TDAL
Sbjct: 75 SIDYEEAEDKRVGLGVSCLVRVTLKDGTYREDIGFGSAENQKCRAMAYEKAKKEAATDAL 134
Query: 127 KRSLRGFGNALGNCLYDKDFLAKIDKV-KFDPPDFDEGNLFRPADELSEMS 176
KR+LR FGN+LGNC YDK+++ ++ ++ K + D +LFR D S+ S
Sbjct: 135 KRALRQFGNSLGNCCYDKNYIREVQRIHKINEKALDSNDLFRNNDATSDES 185
>SPBC119.14 [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 371
Score = 170 bits (431), Expect = 3e-42
Identities = 82/172 (47%), Positives = 122/172 (70%), Gaps = 5/172 (2%)
Query: 1 MEDTGSGKNGKDDIQTKLDK----KLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGY 56
+ D S + D Q K+ K +LGPEYIS+R G G V Y+E WKAI LAN+IFG+
Sbjct: 4 LPDQSSCEEFTDSQQDKMTKLLAMQLGPEYISRRSGPGGGSVTYLEAWKAIELANEIFGF 63
Query: 57 DGWSTEVKNVTIDFLDE-RQGRFSIGCTAIVRVSLADGTFREDIGYGTVENERRKASAFE 115
+GWS+ ++++ +D+++E ++ +F++G + IVRV+L DG+F ED+GYG++EN R KA A+E
Sbjct: 64 NGWSSSIQDIHVDYVEETKEKKFNVGISVIVRVTLKDGSFHEDVGYGSIENCRVKALAYE 123
Query: 116 RAKKSAVTDALKRSLRGFGNALGNCLYDKDFLAKIDKVKFDPPDFDEGNLFR 167
+ KK TDALKR+LR FG+++GNCLYDK ++ KI K+ +F+ NL R
Sbjct: 124 KCKKEGTTDALKRALRNFGSSMGNCLYDKRYIQKILKMAPAQAEFNYDNLLR 175
>Hs20143952 [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 419
Score = 160 bits (406), Expect = 3e-39
Identities = 73/140 (52%), Positives = 100/140 (71%)
Query: 14 IQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEVKNVTIDFLDE 73
IQ L ++LGPEYIS R+ G +V YIEG + INLAN++FGY+GW+ + +DF+D
Sbjct: 39 IQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDL 98
Query: 74 RQGRFSIGCTAIVRVSLADGTFREDIGYGTVENERRKASAFERAKKSAVTDALKRSLRGF 133
G+F +G A VRV L DG++ ED+GYG E + KA + E+A+K AVTD LKR+LR F
Sbjct: 99 NNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALRSF 158
Query: 134 GNALGNCLYDKDFLAKIDKV 153
GNALGNC+ DKD+L ++K+
Sbjct: 159 GNALGNCILDKDYLRSLNKL 178
>Hs20143958 [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 226
Score = 130 bits (326), Expect = 5e-30
Identities = 60/118 (50%), Positives = 82/118 (68%)
Query: 14 IQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEVKNVTIDFLDE 73
IQ L ++LGPEYIS R+ G +V YIEG + INLAN++FGY+GW+ + +DF+D
Sbjct: 39 IQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDL 98
Query: 74 RQGRFSIGCTAIVRVSLADGTFREDIGYGTVENERRKASAFERAKKSAVTDALKRSLR 131
G+F +G A VRV L DG++ ED+GYG E + KA + E+A+K AVTD LKR+LR
Sbjct: 99 NNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALR 156
>Hs20143956 [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 139
Score = 84.7 bits (208), Expect = 2e-16
Identities = 38/77 (49%), Positives = 52/77 (67%)
Query: 14 IQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEVKNVTIDFLDE 73
IQ L ++LGPEYIS R+ G +V YIEG + INLAN++FGY+GW+ + +DF+D
Sbjct: 39 IQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDL 98
Query: 74 RQGRFSIGCTAIVRVSL 90
G+F +G A VRV L
Sbjct: 99 NNGKFYVGVCAFVRVQL 115
>Hs20143954 [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 118
Score = 63.2 bits (152), Expect = 8e-10
Identities = 27/50 (54%), Positives = 37/50 (74%)
Query: 14 IQTKLDKKLGPEYISKRVGFGSSRVAYIEGWKAINLANQIFGYDGWSTEV 63
IQ L ++LGPEYIS R+ G +V YIEG + INLAN++FGY+GW+ +
Sbjct: 39 IQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSI 88
>YDL059c [L] KOG4141 DNA repair and recombination protein RAD52/RAD22
Length = 238
Score = 52.0 bits (123), Expect = 2e-06
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 13/105 (12%)
Query: 41 IEGWKAINLANQIFGYDGWSTEVKNVTI------------DFLDERQGRFSIGCTAIVRV 88
I G I AN+ FGYDGW +V +V + + + ++++ A V+V
Sbjct: 77 IPGHALIQFANETFGYDGWRMDVIDVEARECQPFTAVNNGENTNTSEVKYTVVAEAQVKV 136
Query: 89 SLADGTFREDIGYGTVENERRKASAFERAKKSAVTDALKRSLRGF 133
+L DGT + G G + R + R+KK AV DALK++L F
Sbjct: 137 TLKDGTNTQCGGLGRITLSSR-GECYNRSKKEAVGDALKKALLSF 180
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.128 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,995,949
Number of Sequences: 60738
Number of extensions: 914461
Number of successful extensions: 1923
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1909
Number of HSP's gapped (non-prelim): 10
length of query: 436
length of database: 30,389,216
effective HSP length: 109
effective length of query: 327
effective length of database: 23,768,774
effective search space: 7772389098
effective search space used: 7772389098
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)