ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0639 good I KOG0064 Lipid transport and metabolism Peroxisomal long-chain acyl-CoA transporter, ABC superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0639 225377 222954 -808
(808 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL188c [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ... 741 0.0
Hs9945308 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporte... 318 3e-86
Hs7262393 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporte... 310 4e-84
CE16325 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ... 293 9e-79
7304333 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ... 289 1e-77
Hs4506341 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 247 5e-65
7293647 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 244 4e-64
CE02546 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 240 6e-63
CE02547 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 231 3e-60
At4g39850 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 206 2e-52
YPL147w [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ... 190 9e-48
Hs4826958 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 144 7e-34
Hs10947127 [IR] KOG0060 Long-chain acyl-CoA transporter ABC supe... 144 7e-34
Hs10947129 [IR] KOG0060 Long-chain acyl-CoA transporter ABC supe... 140 6e-33
Hs10947131 [IR] KOG0060 Long-chain acyl-CoA transporter ABC supe... 135 3e-31
CE18253 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 132 2e-30
At1g54350 [IR] KOG0060 Long-chain acyl-CoA transporter ABC super... 129 2e-29
CE05518 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfa... 120 8e-27
Hs18586625 [I] KOG0064 Peroxisomal long-chain acyl-CoA transport... 97 1e-19
Hs10947133 [IR] KOG0060 Long-chain acyl-CoA transporter ABC supe... 76 2e-13
Hs18600750 [I] KOG0064 Peroxisomal long-chain acyl-CoA transport... 69 2e-11
Hs18574231 [I] KOG0064 Peroxisomal long-chain acyl-CoA transport... 69 3e-11
Hs9961246 [U] KOG0058 Peptide exporter ABC superfamily 52 3e-06
7303208 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 52 4e-06
>YKL188c [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 853
Score = 741 bits (1914), Expect = 0.0
Identities = 391/721 (54%), Positives = 510/721 (70%), Gaps = 60/721 (8%)
Query: 107 RHKKISHISGNDLKKQGKKGHNFLIRLILTDRKCXXXXXXXXXXXXXXXXXSLKVAKLDG 166
+ K +H G +++GK +FL +L+L D+KC SL+VA LDG
Sbjct: 95 KESKTNHKGG---ERKGKV--DFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDG 149
Query: 167 ILVSKLVKSEYSNFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKVSDFLLDKYM 226
LVS LV+++Y+NF K+LLG+WM LGIPAS +NSL+ Y T++ A+ INRKVSDFLL KY+
Sbjct: 150 QLVSTLVRAQYANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYL 209
Query: 227 ASHQIFYSINNQPATHSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRDVGAISYNSS 286
++H FYS+ + +E SE+ + LT+D+ S NSS
Sbjct: 210 SNHHTFYSVAS------------AESVSEIQDN--------------LTKDIYTFSMNSS 243
Query: 287 VLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLALGIIVHLSNMGLKLIQPNFTKMQMK 346
+LLNQLLKP LDLILCSF LL++ N++ MGEGTLALG+IV+ SN LKLIQPNFT++ M
Sbjct: 244 LLLNQLLKPMLDLILCSFKLLTS-NTSVMGEGTLALGLIVYASNSLLKLIQPNFTRLTMA 302
Query: 347 KTQLEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHEIRSRALYDFAT 406
LE FRSLHS +HSS+EEIALL+GQ EL N+DY+FYRL +L+ EI++RA+YD AT
Sbjct: 303 SASLESWFRSLHSNLHSSNEEIALLRGQKRELENVDYSFYRLVLFLNREIKARAIYDVAT 362
Query: 407 TFVIKYTWGAAGLLLCSIPIFLQDTVSKDK----------TAEFITNRRLLLTASSSIGR 456
FVIKYTWGAAGL+LCSIPIF ++ S+D TA+FITNRRLL+TASSSIGR
Sbjct: 363 AFVIKYTWGAAGLVLCSIPIFFKNKPSEDTLQLKEPGNDMTADFITNRRLLVTASSSIGR 422
Query: 457 FVQLRRNIQQLQGVSLRLNKFNDELD-NIINAPKE-RDDTVPVEYDDNVIEFQNVPLITP 514
FV+L+RNIQQL+G+ LRLNKFND LD N + KE RD+ VEYDD+ I+F+N+PLITP
Sbjct: 423 FVELKRNIQQLRGIRLRLNKFNDLLDANKGDDEKEPRDERCIVEYDDSRIKFENIPLITP 482
Query: 515 TGQVLISELTFKLERFNHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRR 574
QVL+ EL+F L+ NHLLIIGPNGCGKSSLFR+LGGLWPI + N Q+KLIMP RR
Sbjct: 483 ANQVLVPELSFDLKHGNHLLIIGPNGCGKSSLFRILGGLWPIRATPNKNHQSKLIMP-RR 541
Query: 575 NDNNESTVYYLPQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLEL 634
+ + ++YLPQRPYM N+STFREQ+IYPD++E F +++ GD L+ IL +L+L
Sbjct: 542 TVDRDCAIFYLPQRPYMGNRSTFREQIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDL 601
Query: 635 DDLINENLSIVMAKANKKECS---------------VEDSFQLVRPWSEELTMGIQQRLA 679
+DL+ EN+S+++A+ K S V D+F +VR WSEELT+G+QQRLA
Sbjct: 602 EDLVTENMSLLLAQRTSKNDSQQLSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLA 661
Query: 680 MARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITVLSVCHRTTLWHFHTHLLSFD 739
MARMYYHKP FAVLDECTSAV+PEMEQ+MY++AQ+ GI+++SVCHRT+LWHFH +LL FD
Sbjct: 662 MARMYYHKPKFAVLDECTSAVAPEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFD 721
Query: 740 GKGNYKFGKFNPNQRXXXXXXXXXXXXXXXQDVPIMQKRLDELNIAKRSNLLKSSQSNLA 799
GKG Y+FG FNP +R Q VP+ +++L +L IAK SN+++ S++NL
Sbjct: 722 GKGGYQFGPFNPKERLCNEEKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLN 781
Query: 800 L 800
L
Sbjct: 782 L 782
>Hs9945308 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 740
Score = 318 bits (814), Expect = 3e-86
Identities = 214/675 (31%), Positives = 341/675 (49%), Gaps = 102/675 (15%)
Query: 158 SLKVAKLDGILVSKLVKSEYSNFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKV 217
S+ VA LDG +V +V+ + FI L+ +W+ + IPA+ VNS +RY+ A+A ++
Sbjct: 121 SIYVAGLDGKIVKSIVEKKPRTFIIKLI-KWLMIAIPATFVNSAIRYLECKLALAFRTRL 179
Query: 218 SDFLLDKYMASHQIFYSINNQPATHSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRD 277
D + Y ++Q +Y + N + +P Q LT D
Sbjct: 180 VDHAYETYF-TNQTYYKVINMDGRLA-------------------------NPDQSLTED 213
Query: 278 VGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGE--GTLALGIIVHLSNMGLKL 335
+ S + + L + L KP LD++L S+TL+ A S TL G++V+ + LK
Sbjct: 214 IMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKA 273
Query: 336 IQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHE 395
P F K+ ++ +G R +HS+I ++ EEIA +G E+ L ++ L ++
Sbjct: 274 CSPKFGKLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLI 333
Query: 396 IRSRALYDFATTFVIKYTWGAAGLLLCSIPIFL-----------QDTVSKDKTAEFITNR 444
+ R Y F++KY W ++GL++ +IPI + + ++T F T R
Sbjct: 334 LSKRLWYIMIEQFLMKYVWSSSGLIMVAIPIITATGFADGEDGQKQVMVSERTEAFTTAR 393
Query: 445 RLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKER------------- 491
LL + + +I R + + + +L G + R+ D + +R
Sbjct: 394 NLLASGADAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKN 453
Query: 492 --------DDTVPVEYD----DNVIEFQNVPLITPTGQVLISELTFKLERFNHLLIIGPN 539
DT+ ++ D+ I +NVP+ITP G+V+ S L FK+E HLLI GPN
Sbjct: 454 GAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPN 513
Query: 540 GCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFRE 599
GCGKSSLFR+L GLWP+ + + L PP ++ ++Y+PQRPYMS S R+
Sbjct: 514 GCGKSSLFRILSGLWPVYEGV-------LYKPPPQH------MFYIPQRPYMSLGS-LRD 559
Query: 600 QLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSVEDS 659
Q+IYPD+++D K G DQ L ILH + L ++ E
Sbjct: 560 QVIYPDSVDDMHDK-----GYTDQDLERILHNVHLYHIVQR----------------EGG 598
Query: 660 FQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITV 719
+ V W + L+ G +QR+ MARM+YHKP +A+LDECTSAVS ++E K+++ A+ GI++
Sbjct: 599 WDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISL 658
Query: 720 LSVCHRTTLWHFHTHLLSFDGKGNYKFGKFNPNQRXXXXXXXXXXXXXXXQDVPIMQKRL 779
LS+ HR +LW +HTHLL FDG+G ++F + + R +P MQ+RL
Sbjct: 659 LSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLA-GIPKMQQRL 717
Query: 780 DEL-NIAKRSNLLKS 793
+EL I ++LK+
Sbjct: 718 NELCKILGEDSVLKT 732
>Hs7262393 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 745
Score = 310 bits (795), Expect = 4e-84
Identities = 207/672 (30%), Positives = 337/672 (49%), Gaps = 110/672 (16%)
Query: 158 SLKVAKLDGILVSKLVKSEYSNFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKV 217
S+ VA+LDG L +V+ + F LL QW+ + +PA+ VNS +RY+ A++ ++
Sbjct: 108 SVYVARLDGRLARCIVRKDPRAFGWQLL-QWLLIALPATFVNSAIRYLEGQLALSFRSRL 166
Query: 218 SDFLLDKYMASHQIFYSINNQPATHSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRD 277
Y S Q +Y ++N +P Q LT D
Sbjct: 167 VAHAYRLYF-SQQTYYRVSNMDGR-------------------------LRNPDQSLTED 200
Query: 278 VGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEG--TLALGIIVHLSNMGLKL 335
V A + + + L + L KP LD+ + S+TLL A S G + G++V L+ L+
Sbjct: 201 VVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRA 260
Query: 336 IQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHE 395
P F ++ ++ + +G R +HS++ ++SEEIA G EL L ++ L S ++
Sbjct: 261 FSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLI 320
Query: 396 IRSRALYDFATTFVIKYTWGAAGLLLCSIPIFL--------------------QDTVSKD 435
+ R Y F++KY W A+GLL+ ++PI ++ + +
Sbjct: 321 LLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSE 380
Query: 436 KTAEFITNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNI----INAPKER 491
+T F R LL A+ +I R + + + +L G + R+++ +++ P+E
Sbjct: 381 RTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPREL 440
Query: 492 DDTV---------------PVEYDDNVIEF------QNVPLITPTGQVLISELTFKLERF 530
+D P++ V++ +N+P++TP+G+V+++ L ++E
Sbjct: 441 EDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEG 500
Query: 531 NHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPY 590
HLLI GPNGCGKSSLFR+LGGLWP + L PP + ++Y+PQRPY
Sbjct: 501 MHLLITGPNGCGKSSLFRILGGLWPTYGGV-------LYKPPPQR------MFYIPQRPY 547
Query: 591 MSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKAN 650
MS + R+Q+IYPD++ED +K G +Q L IL V+ L ++
Sbjct: 548 MS-VGSLRDQVIYPDSVEDMQRK-----GYSEQDLEAILDVVHLHHILQR---------- 591
Query: 651 KKECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYK 710
E ++ + W + L+ G +QR+ MARM+YH+P +A+LDECTSAVS ++E K+++
Sbjct: 592 ------EGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQ 645
Query: 711 HAQDLGITVLSVCHRTTLWHFHTHLLSFDGKGNYKFGKFNPNQRXXXXXXXXXXXXXXXQ 770
A+D GI +LS+ HR +LW +HTHLL FDG+G +KF K + R
Sbjct: 646 AAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLA- 704
Query: 771 DVPIMQKRLDEL 782
+P MQ+RL EL
Sbjct: 705 GIPKMQRRLQEL 716
>CE16325 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 734
Score = 293 bits (749), Expect = 9e-79
Identities = 197/663 (29%), Positives = 320/663 (47%), Gaps = 103/663 (15%)
Query: 161 VAKLDGILVSKLVKSEYSNFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKVSDF 220
VA+L+G +V +V+ F+ L+ +W+ + +PA+ VNS++R+ +A +++
Sbjct: 113 VAQLEGSMVQAIVEKNVLQFVLHLV-KWILVALPATFVNSMIRFFESYLGLAFRTRLTKH 171
Query: 221 LLDKYMASHQIFYSINNQPATHSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRDVGA 280
+Y S Q +Y+++N DT L ++ Q LT D+
Sbjct: 172 AYKQYF-SDQTYYAVSNL------------------------DTRLQNAD-QCLTEDITM 205
Query: 281 ISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLALGII----VHLSNMGLKLI 336
S + + L + L KP LD+ L +FTL+ A G T + V L+ L+ +
Sbjct: 206 FSQSVAHLYSHLTKPVLDVALITFTLIKLAIQRGTGRSTFLPSCMAIMAVSLTAKILRAV 265
Query: 337 QPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHEI 396
P F M ++ + +G R LHS+I ++SEEIA G E LD AF LY +
Sbjct: 266 SPRFGHMVAEEARRKGHLRYLHSRIITNSEEIAFYGGHQAEYKQLDGAFNSLYQQMMLIF 325
Query: 397 RSRALYDFATTFVIKYTWGAAGLLLCSIPIF---------------LQDTVSKDKTAEFI 441
+ R Y F++KY W G+++ ++PI L D ++T +
Sbjct: 326 KKRIPYIMIEQFLMKYVWSGTGMVMIALPILATEYADDEKSTKLEDLPDRGVSERTRGYA 385
Query: 442 TNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNK----FNDELDNIINAPK-------- 489
T + LL ++ ++ R + + + +L G + R+++ F+D I
Sbjct: 386 TAKTLLFNSADAVERLMTSYKEVTELAGYTGRVHEMFQVFDDAKKGIYQRQTVSAGAEQG 445
Query: 490 ---ERDDTVPVE-----YDDNVIEFQNVPLITPTGQVLISELTFKLERFNHLLIIGPNGC 541
ER DT +E + + I +VP++TP G V++ +T + H+LI GPNGC
Sbjct: 446 QRGERFDTSKIEGIITDSEADEIILNSVPIVTPNGDVVVKNMTLTISPGMHVLITGPNGC 505
Query: 542 GKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQL 601
GKSSLFR+LGGLWP+ + +YY+PQRPYM+ T R+Q+
Sbjct: 506 GKSSLFRILGGLWPVYRG-------------HLEKPTSDRMYYIPQRPYMT-LGTLRDQV 551
Query: 602 IYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSVEDSFQ 661
IYPDT ++ G DQ L+ +L ++ L+ ++ E +
Sbjct: 552 IYPDTTIQMRRQ-----GITDQDLMTMLRIVHLEHIVER----------------EGGWD 590
Query: 662 LVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITVLS 721
W + L+ G +QR+ MAR++YH+P +A+LDECTSAVS ++E +Y+ +D GIT+L+
Sbjct: 591 AQNDWMDVLSGGEKQRMGMARVFYHRPKYALLDECTSAVSIDVEGSIYQAIKDSGITLLT 650
Query: 722 VCHRTTLWHFHTHLLSFDGKGNYKFGKFNPNQRXXXXXXXXXXXXXXXQ--DVPIMQKRL 779
V HR +LW FHTHLL +DG+G YK N Q +VP ++RL
Sbjct: 651 VTHRPSLWKFHTHLLQYDGEGGYKVSSLNEKTIGERMSYSEEKQQLEKQLAEVPRWKERL 710
Query: 780 DEL 782
+E+
Sbjct: 711 EEV 713
>7304333 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 730
Score = 289 bits (739), Expect = 1e-77
Identities = 190/637 (29%), Positives = 318/637 (49%), Gaps = 101/637 (15%)
Query: 158 SLKVAKLDGILVSKLVKSEYSNFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKV 217
S+ VA L+G LV +V+ + F VLL +W + IPA+ VNS++R++ ++A ++
Sbjct: 146 SIYVAALEGALVKFIVRKDIKQFALVLL-KWFGIAIPATFVNSMIRFLESKLSLAFRTRL 204
Query: 218 SDFLLDKYMASHQIFYSINNQPATHSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRD 277
Y +Q +Y ++N LD + E+ D LT D
Sbjct: 205 VRHSYRLYF-KNQNYYRVSN------------------LDG-RIENAD------HRLTED 238
Query: 278 VGAISYNSSVLLNQLLKPTLDLILCSFTLLSNAN---STFMGEGTLALGIIVHLSNMGLK 334
+ + + + L + L KP DL+L L+ ++ + + L++G+I +++ L+
Sbjct: 239 ISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHI-LR 297
Query: 335 LIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSH 394
++ P F ++ ++ G R +HS+I +++EEIA G E+ L A+ RL + ++
Sbjct: 298 IVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTT 357
Query: 395 EIRSRALYDFATTFVIKYTWGAAGLLLCSIPIFLQDTVS--------------KDKTAEF 440
+ + F +KY W G+++ S+PI V ++T
Sbjct: 358 IFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESRVSERTQYL 417
Query: 441 ITNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERDDTVPVEYD 500
T R LL++A+ +I R + + I L G + R+ D + + +
Sbjct: 418 TTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNQS 477
Query: 501 DNVIEFQN------------------------VPLITPTGQVLISELTFKLERFNHLLII 536
+ +IEF+N VP++TP +++ +LT +E HLLI
Sbjct: 478 NGIIEFRNGKPIAKGRIIYSDDPKNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLIT 537
Query: 537 GPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKST 596
GPNGCGKSSLFR+L GLWPI +L +P R + ++Y+PQRPYMS S
Sbjct: 538 GPNGCGKSSLFRILSGLWPIYAG-------ELHIP--RPVKDVPCMFYIPQRPYMSIGSL 588
Query: 597 FREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSV 656
+Q+IYPDT ED +K H+ E L ++ + + +
Sbjct: 589 C-DQIIYPDTREDMKRK----------------HITE------NELRSILKMVSLEHIAQ 625
Query: 657 EDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLG 716
DSF +VR W + L+ G +QR+A+AR++YH+P +A+LDECTSAVS ++E +Y+ A+ +G
Sbjct: 626 RDSFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMG 685
Query: 717 ITVLSVCHRTTLWHFHTHLLSFDGKGNYKFGKFNPNQ 753
IT+L++ HR TLW +HTH+L FDG GN++F K N ++
Sbjct: 686 ITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDE 722
>Hs4506341 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 659
Score = 247 bits (631), Expect = 5e-65
Identities = 177/577 (30%), Positives = 284/577 (48%), Gaps = 92/577 (15%)
Query: 196 SIVNSLLRYMTRISAIAINRKVSDFLLDKYMASHQIFYSINNQPATHSLTLSQKSEEKSE 255
S+VN+ L+Y + +++ +L ++Y+ + +Y + N
Sbjct: 137 SLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFT-YYKMGNL----------------- 178
Query: 256 LDSDKPEDTDLSDSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFM 315
D +++ P Q LT+DV + L + L KP LD++L F L S +
Sbjct: 179 -------DNRIAN-PDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGA--- 227
Query: 316 GEGTLALGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQT 375
+G ++ + +S + L ++ KM + + + EG +R ++S++ ++SEEIA G
Sbjct: 228 -QGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNK 286
Query: 376 TELWNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIF-------L 428
E + F +L +L + I R F + + KY G L+ S P L
Sbjct: 287 REKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHL 346
Query: 429 QDTVSKDKTAEFITNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAP 488
+ T S + ++ + R+LL S ++GR V R + +L G + R+ + L ++ +
Sbjct: 347 KSTHS-ELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGK 405
Query: 489 KERD------------DTVP-------VEYDDNVIEFQNVPLITPTGQVLISELTFKLER 529
ER +P + DN+I+F +VPL TP G VLI +L F++
Sbjct: 406 YERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRS 465
Query: 530 FNHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRP 589
++LI GPNGCGKSSLFRVLG LWP+ +L P R ++Y+PQRP
Sbjct: 466 GANVLICGPNGCGKSSLFRVLGELWPLFGG-------RLTKPER------GKLFYVPQRP 512
Query: 590 YMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKA 649
YM+ T R+Q+IYPD ED +K G D L L ++L ++
Sbjct: 513 YMT-LGTLRDQVIYPDGREDQKRK-----GISDLVLKEYLDNVQLGHILER--------- 557
Query: 650 NKKECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMY 709
E + V+ W + L+ G +QR+AMAR++YHKP FA+LDECTSAVS ++E +Y
Sbjct: 558 -------EGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIY 610
Query: 710 KHAQDLGITVLSVCHRTTLWHFHTHLLSFDGKGNYKF 746
H + +GIT+ +V HR +LW H + L DG+GNY+F
Sbjct: 611 SHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEF 647
>7293647 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 618
Score = 244 bits (623), Expect = 4e-64
Identities = 170/581 (29%), Positives = 284/581 (48%), Gaps = 92/581 (15%)
Query: 200 SLLRYMTRISAIAINRKVSDFLLDKYMASHQIFYSINNQPATHSLTLSQKSEEKSELDSD 259
+LL+Y+T + AI++ V + L + ++ + N +S L+ + K +
Sbjct: 98 ALLKYLTALPAISVVTNVLKWSLGEL----KLRFRTNLTHHLYSQYLNGYTYYKMSNLDN 153
Query: 260 KPEDTDLSDSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGT 319
+ + D Q LT D+ +++ L + + KP LD+ + + L T
Sbjct: 154 RIANAD------QLLTTDIDKFCESATDLYSNISKPVLDIFIYVYRL------------T 195
Query: 320 LALGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELW 379
+ LG G P+ ++ +LEG FR ++S++ ++SEE+A +G E
Sbjct: 196 VNLG--------GKTPFDPDALPALRRRQKLEGEFRYVNSRLITNSEEVAFYQGNVREKL 247
Query: 380 NLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIF------LQDTVS 433
L ++ +L S+L + R + KY G SIP F L S
Sbjct: 248 TLLASYSKLRSHLRKFLEFRVSMGIIDNIIGKYFASIVGFYAVSIPFFSENHPLLSGENS 307
Query: 434 KDKTAEFITNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERD- 492
+ + T R+L+ + +IGR V R + +L G + R+ + L ++ ER
Sbjct: 308 GQRLQAYYTYGRMLVKLAEAIGRLVLAGREMSRLAGFTARMTELIKVLSDLNKGTYERTM 367
Query: 493 --------------------DTVPVEYDDNVIEFQNVPLITPTGQVLISELTFKLERFNH 532
+ + ++DN+I F+ VPL+TP G VL+ EL+F+++ +
Sbjct: 368 VNGNNLAQNAVGSASSNFGPNKGIMCFEDNIIRFEKVPLVTPNGDVLLQELSFEVKSGTN 427
Query: 533 LLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMS 592
+L+ GPNGCGKSSLFR+LG LWP K+ P R ++Y+PQRPYM+
Sbjct: 428 VLVCGPNGCGKSSLFRILGELWPTWGG-------KVTKPSR------GKLFYVPQRPYMT 474
Query: 593 NKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKK 652
T R+Q+IYP T +D + +G D+ L+ L +++L L
Sbjct: 475 -LGTLRDQIIYPHTRDDMRR-----LGHSDEDLMHYLDIVQLTYLEQR------------ 516
Query: 653 ECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHA 712
E+ + W + L+ G +QR+AMAR++YHKP FA+LDECTSAVS ++E KMY +
Sbjct: 517 ----ENGLDSIEDWIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYC 572
Query: 713 QDLGITVLSVCHRTTLWHFHTHLLSFDGKGNYKFGKFNPNQ 753
+++GIT+ +V HR +LW H + L FDG+G+Y+F + ++
Sbjct: 573 REVGITLFTVSHRKSLWAHHDYYLQFDGRGSYEFATIDQDK 613
>CE02546 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 665
Score = 240 bits (613), Expect = 6e-63
Identities = 176/580 (30%), Positives = 279/580 (47%), Gaps = 89/580 (15%)
Query: 191 LGIPA-SIVNSLLRYMTRISAIAINRKVSDFLLDKYMASHQIFYSINNQPATHSLTLSQK 249
L +PA S++N+LL++ + ++ +L KY+ +Y I+N
Sbjct: 139 LNLPAISLINALLKFSLSELKLRFRENLTKYLYGKYLGGFT-YYQISN------------ 185
Query: 250 SEEKSELDSDKPEDTDLSDSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSN 309
LDS +P Q LT+DV L + + KP LD+ L F L
Sbjct: 186 ------LDSR-------IQNPDQLLTQDVEKFCDGIVELYSNMTKPILDVFLYVFKL--G 230
Query: 310 ANSTFMGEGTLALGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIA 369
+ G G L G ++ + KL +P K+ +++ LEG +R ++S++ +SEEIA
Sbjct: 231 RALGWEGPGLL-FGYLMASMVVLTKLRRP-IAKLTVEEQVLEGEYRYVNSRLIMNSEEIA 288
Query: 370 LLKGQTTELWNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIF-- 427
+G E L +F L +L I R F V KY G + C+ F
Sbjct: 289 FYQGNKPEKQALMGSFNNLVYHLRKTIMFRFTLGFVDNIVGKYITNIVGWVACAKTFFDV 348
Query: 428 ----LQDTVSKDKTAEFITNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDN 483
+ + E N R++L S ++GR R++ +L G + R++ LD+
Sbjct: 349 NNEKFNEMDRNELMQELYNNGRMMLKLSEALGRLALAGRDMTRLSGFTTRVDTLMKVLDD 408
Query: 484 IINAPKERDDTVPVEYD-----------------DNVIEFQNVPLITPTGQVLISELTFK 526
+ E+ + DN+I+F VPL+TP G +LI L+F+
Sbjct: 409 MKAGRFEKAQVADESGEEGQRLMLKAGSGKLLAQDNMIKFDEVPLVTPNGDILIESLSFE 468
Query: 527 LERFNHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLP 586
+ ++L+ GPNGCGKSSLFR LG LWP+ + L P + ++Y+P
Sbjct: 469 VPSGRNVLVCGPNGCGKSSLFRTLGELWPV-------MGGTLTKPAK------GKLFYVP 515
Query: 587 QRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVM 646
QRPYM+ T R+Q+IYPDT D K G D+ L +L ++L +++
Sbjct: 516 QRPYMT-LGTLRDQVIYPDTSFDMKMK-----GMSDKDLEQMLENVQLTNILER------ 563
Query: 647 AKANKKECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQ 706
E + V+ W + L+ G +QR+AMAR++YHKP FA+LDECTSAVS ++E
Sbjct: 564 ----------EGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEG 613
Query: 707 KMYKHAQDLGITVLSVCHRTTLWHFHTHLLSFDGKGNYKF 746
MY+ +++ IT+ +V HR +LW +H + L DG+G+Y+F
Sbjct: 614 AMYRLCREMNITLFTVSHRKSLWKYHEYSLYMDGRGSYRF 653
>CE02547 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 661
Score = 231 bits (589), Expect = 3e-60
Identities = 170/581 (29%), Positives = 278/581 (47%), Gaps = 90/581 (15%)
Query: 191 LGIPA-SIVNSLLRYMTRISAIAINRKVSDFLLDKYMASHQIFYSINNQPATHSLTLSQK 249
L +PA S+ N++L++ + ++S L +Y+ FY ++N
Sbjct: 134 LNLPAISVTNAILKFGIAELKLRFRERLSTHLYSQYLKGFT-FYKMSNL----------- 181
Query: 250 SEEKSELDSDKPEDTDLSDSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSN 309
DT + ++ Q LT+DV L + L KP LD+ L F L
Sbjct: 182 -------------DTRIQNAD-QLLTQDVDRFCDGIVELYSNLSKPILDVFLYLFRL--- 224
Query: 310 ANSTFMGEGTLALGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIA 369
S ++ ++ + +GL ++ ++ +++ LEG +R ++S++ +SEEIA
Sbjct: 225 GTSLGFSSPSILFSYLL-FTGVGLTYLRRPIGRLTVEEQALEGEYRYVNSRLIMNSEEIA 283
Query: 370 LLKGQTTELWNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIFLQ 429
+G +E + F L +L I R F V KY G F +
Sbjct: 284 FYQGNQSEKETIMSTFASLVQHLRKIILFRFSIGFVDNIVAKYLATVVGWYAVGSSFFDK 343
Query: 430 DT-----VSKDKTA-EFITNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDN 483
+S+++ E+ + R++ + ++GR R++ +L G + R++ + LD+
Sbjct: 344 QHKPFIGMSRNQLMQEYYNSGRMMYKMAEALGRLALAGRDMTRLSGFTSRVDTLLNVLDD 403
Query: 484 I---------INAPKERDDTVPVEY---------DDNVIEFQNVPLITPTGQVLISELTF 525
+ + +E + E DNVI F NVPL+TP G VLI L F
Sbjct: 404 VNSGNYKRTMVGEKEESSALIKSELVAGSGNLRVQDNVIRFDNVPLVTPNGDVLIERLNF 463
Query: 526 KLERFNHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYL 585
++ ++L+ GPNGCGKSSLFRVLG LWP+ L P + ++Y+
Sbjct: 464 EVPSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGT-------LTKPAK------GKLFYV 510
Query: 586 PQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIV 645
PQRPYM+ T R+Q+IYPD D I+K G D L +L ++L ++
Sbjct: 511 PQRPYMT-LGTLRDQIIYPDRPLDMIRK-----GVSDSDLEQMLENVQLTHILER----- 559
Query: 646 MAKANKKECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEME 705
E + V+ W + L+ G +QR+AMAR++YHKP FA+LDECTSAVS ++E
Sbjct: 560 -----------EGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVE 608
Query: 706 QKMYKHAQDLGITVLSVCHRTTLWHFHTHLLSFDGKGNYKF 746
MY+ ++ IT+ +V HR +LW +H + L DG+G+Y+F
Sbjct: 609 GAMYRLCREKNITLFTVSHRKSLWKYHEYSLYMDGRGSYRF 649
>At4g39850 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 1383
Score = 206 bits (523), Expect = 2e-52
Identities = 171/645 (26%), Positives = 300/645 (46%), Gaps = 107/645 (16%)
Query: 119 LKKQGKKGHNFLIRLILTDRKCXXXXXXXXXXXXXXXXXSLKVAKLDGILVSKLVKSEYS 178
L + GK G L+ L+ T S ++AK+ G L
Sbjct: 98 LSQMGKMGARDLLALVAT--------------VVFRTALSNRLAKVQGFLFRAAFLRRAP 143
Query: 179 NFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKVSDFLLDKYMASHQIFYSINNQ 238
F++ L+ + + L S ++S +Y+T ++ RK+ ++ + + ++Y I++
Sbjct: 144 LFLR-LISENIMLCFMLSTLHSTSKYITGALSLRF-RKILTKIIHSHYFENMVYYKISHV 201
Query: 239 PA--THSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRDVGAISYNSSVLLNQLLKPT 296
TH P Q + DV S S L+ L
Sbjct: 202 DGRITH---------------------------PEQRIASDVPRFSSELSDLILDDLTAV 234
Query: 297 LDLILCSFTLLSNANSTFMGEGTLALGIIVHLSNMG--LKLIQPNFTKMQMKKTQLEGLF 354
D IL ++ L S A+ ++ I+ ++ G ++ P+F K+ K+ QLEG +
Sbjct: 235 TDGILYAWRLCSYASPKYI------FWILAYVLGAGTAIRNFSPSFGKLMSKEQQLEGEY 288
Query: 355 RSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTW 414
R LHS++ + SE IA G+T E ++ F L S++SH + + F++KY
Sbjct: 289 RQLHSRLRTHSESIAFYGGETREESHIQQKFKNLVSHMSHVLHDHWWFGMIQDFLLKYLG 348
Query: 415 GAAGLLLCSIPIFLQDTVSKDKT---AEFITNRR----LLLTASSSIGRFVQLRRNIQQL 467
++L P F D T AE ++N R ++++ ++G R + +L
Sbjct: 349 ATVAVILIIEPFFSGHLRPDDSTLGRAEMLSNIRYHTSVIISLFQALGTLSISSRRLNRL 408
Query: 468 QGVSLRLNKF---NDELDNIINAPKERDDTVPVEYDDNVIEFQNVPLITPTGQVLISELT 524
G + R+++ + EL + +R+ + + N +EF +V ++TPTG VL+ +LT
Sbjct: 409 SGYADRIHELMAVSRELSGDDKSSFQRNRSRNYLSEANYVEFSDVKVVTPTGNVLVEDLT 468
Query: 525 FKLERFNHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYY 584
++E+ ++LLI G GLWP+ + ++ P +D N+ ++Y
Sbjct: 469 LRVEQGSNLLITG--------------GLWPL-------VSGHIVKPGVGSDLNKE-IFY 506
Query: 585 LPQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSI 644
+PQRPYM+ T R+QLIYP T + LL + ++EL +N+SI
Sbjct: 507 VPQRPYMA-VGTLRDQLIYPLT------------SGQESELLTEIGMVEL----LKNVSI 549
Query: 645 VMAKANKKECSVEDSFQLVRP-----WSEELTMGIQQRLAMARMYYHKPIFAVLDECTSA 699
+++ + +E +P W +EL++G QQRL MAR++YHKP FA+LDECTSA
Sbjct: 550 LVSLFYTRMVDLEYLLDRYQPEKEVNWGDELSLGEQQRLGMARLFYHKPKFAILDECTSA 609
Query: 700 VSPEMEQKMYKHAQDLGITVLSVCHRTTLWHFHTHLLSFDGKGNY 744
V+ +ME++ + +G + +++ HR L FH +LS DG+G +
Sbjct: 610 VTTDMEERFAAKVRAMGTSCITISHRPALVAFHDVVLSLDGEGGW 654
Score = 104 bits (260), Expect = 5e-22
Identities = 131/604 (21%), Positives = 252/604 (41%), Gaps = 126/604 (20%)
Query: 160 KVAKLDGILVSKLVKSEYSNFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKVSD 219
++A L+G V +++ + + F++ L+G + +SI+ LR++T+ A+ +++
Sbjct: 825 RIASLNGTTVKYVLEQDKAAFVR-LIGLSVLQSGASSIIAPSLRHLTQRLALGWRIRLTQ 883
Query: 220 FLLDKYMASHQIFYSINNQPATHSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRDVG 279
LL Y+ ++ FY + + + +D+D Q LTRD+
Sbjct: 884 HLLRNYLRNNA-FYKVFHMSG-------------NSIDAD------------QRLTRDLE 917
Query: 280 AISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLALGIIVHLSNMGLKLIQPN 339
++ + S LL ++KP++D++ + +N FM G L + L L+ + P+
Sbjct: 918 KLTADLSGLLTGMVKPSVDILWYVRYVGLISNICFM-RGVAILYTYMLLGLGFLRRVAPD 976
Query: 340 FTKMQMKKTQLEGLFRS--------LHSKIHSSSEEIALLKGQTTE-------------- 377
F + ++ QLEG FR +H ++++ +E IA G E
Sbjct: 977 FGDLAGEEQQLEGKFRPTSSCLCRFMHERLNTHAESIAFFGGGAREKAVSFLIALAIAAG 1036
Query: 378 LW-----------NLDYAFY------------------RLYSYLSHE---IRSRALYDFA 405
W NL+ ++ + + L H +R + LY
Sbjct: 1037 FWVVIFESKLPEVNLELFYHLCDDGLFMSNVASLMVDKKFRALLDHSLMLLRKKWLYGIL 1096
Query: 406 TTFVIK-----YTWGAAGLLLCS--------------IPIFLQDTVSKDKTAEFITNRRL 446
FV K TWG + L + + + + A + R L
Sbjct: 1097 DDFVTKQLPNNVTWGLSLLYALEHKGDRALVSTQVKYLHVLYMMLLIPGELAHAL--RYL 1154
Query: 447 LLTASSSIGRF---VQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERDDTVPVEYDDNV 503
S S F ++L + +L G R+ + ++ LD + + T ++ D +
Sbjct: 1155 ASVVSQSFMAFGDILELHKKFLELSGGINRIFELDEFLDASQSGVTSENQTSRLDSQD-L 1213
Query: 504 IEFQNVPLITPTGQVLISELTFKLERFNHLLIIGPNGCGKSSLFRVLGGLWP--ISKSLN 561
+ F V +ITP +++ S+L+ ++ LL+ GPNG GK+S+FRVL +WP +
Sbjct: 1214 LSFSEVDIITPAQKLMASKLSCEIVSGKSLLVTGPNGSGKTSVFRVLRDIWPTVCGRLTK 1273
Query: 562 PCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAG 621
P L K + + + ++++PQRPY + T R+Q+IYP + E+ K+ +G
Sbjct: 1274 PSLDIKEL-------GSGNGMFFVPQRPY-TCLGTLRDQIIYPLSKEEAEKRAAKLYTSG 1325
Query: 622 DQALLGILHVLELDDLINENLSIVMAKANKKECSVED--SFQLVRPWSEELTMGIQQRLA 679
+ + E +++ +L ++ D + W + L++G QQRL
Sbjct: 1326 ESS-------TEAGSILDSHLKTILENVRLVYLLERDVGGWDATTNWEDILSLGEQQRLG 1378
Query: 680 MARM 683
M +
Sbjct: 1379 MVSL 1382
>YPL147w [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 870
Score = 190 bits (482), Expect = 9e-48
Identities = 160/657 (24%), Positives = 288/657 (43%), Gaps = 129/657 (19%)
Query: 158 SLKVAKLDGILVSKLVKSEYSNFIKVLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKV 217
SL VAKLDG +V ++ +F+ L G W + +PAS NS ++ + R ++ +
Sbjct: 224 SLFVAKLDGQIVKNIIAGRGRSFLWDL-GCWFLIAVPASYTNSAIKLLQRKLSLNFRVNL 282
Query: 218 SDFLLDKYMASHQIFYS-INNQPATHSLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTR 276
+ ++ D Y+ FY I + A++S+ +D+ +T
Sbjct: 283 TRYIHDMYLDKRLTFYKLIFDAKASNSVI--------KNIDNS--------------ITN 320
Query: 277 DVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLALGIIVHLSNMGLKLI 336
DV + + + KP +DLI S L N + G + + ++ L+
Sbjct: 321 DVAKFCDATCSVFANIAKPVIDLIFFSVYLRDNLGTV----GVAGIFVNYFITGFILRKY 376
Query: 337 QPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHEI 396
P K+ +++ +G + + H + ++SEEIA +G E + + L +
Sbjct: 377 TPPLGKLAGERSASDGDYYNYHLNMINNSEEIAFYQGTAVERTKVKELYDVLMEKMLLVD 436
Query: 397 RSRALYDFATTFVIKYTWGAAGLLLCSIPIFLQDTV----SKDKTA-EFITNRRLLLTAS 451
+ + Y+ +V+KYTW G + SIPI + S++K EFI N+RL+L+ +
Sbjct: 437 KVKFGYNMLEDYVLKYTWSGLGYVFASIPIVMSTLATGINSEEKNMKEFIVNKRLMLSLA 496
Query: 452 SSIGRFVQLRRNIQQLQGVSLRLNKFNDEL---------------------------DNI 484
+ R + ++I QL G + R+ L N+
Sbjct: 497 DAGSRLMHSIKDISQLTGYTNRIFTLLSVLHRVHSLNFNYGAVPSILSIRTEDASRNSNL 556
Query: 485 INAPKERDDTV--PVEYDDNVIEFQNVPLITPT-----GQVLISELTFKLERF------- 530
+ D + ++ + N I +N+ +I P+ G LI++LTF++
Sbjct: 557 LPTTDNSQDAIRGTIQRNFNGIRLENIDVIIPSVRASEGIKLINKLTFQIPLHIDPITSK 616
Query: 531 ----------------------NHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKL 568
+ LLI+GPNGCGKSS+ R++ +WP+ + L
Sbjct: 617 SNSIQDLSKANDIKLPFLQGSGSSLLILGPNGCGKSSIQRIIAEIWPVYN------KNGL 670
Query: 569 IMPPRRNDNNESTVYYLPQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGI 628
+ P +E+ ++++PQ+PY S T R+Q+IYP + ++F + G D+ L+ I
Sbjct: 671 LSIP-----SENNIFFIPQKPYFSRGGTLRDQIIYPMSSDEFFDR-----GFRDKELVQI 720
Query: 629 LHVLELDDLINENLSIVMAKANKKECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKP 688
L ++LD L+ + + A + W + L+ G +QR+ AR+ +HKP
Sbjct: 721 LVEVKLDYLLKRGVGLTYLDA-------------IADWKDLLSGGEKQRVNFARIMFHKP 767
Query: 689 IFAVLDECTSAVSPEMEQKMYKHAQDLGITVLSVCHRTTLWHFHTHLLSF----DGK 741
++ VLDE T+A+S +ME ++ + +S+ R TL +H LL DGK
Sbjct: 768 LYVVLDEATNAISVDMEDYLFNLLKRYRFNFISISQRPTLIKYHEMLLEIGENRDGK 824
>Hs4826958 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 606
Score = 144 bits (362), Expect = 7e-34
Identities = 138/504 (27%), Positives = 228/504 (44%), Gaps = 70/504 (13%)
Query: 268 DSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLA------ 321
D+P Q +++DV QL LI+ FTL+ F G L
Sbjct: 140 DNPDQRISQDVERFC-------RQLSSMASKLIISPFTLVYYTYQCFQSTGWLGPVSIFG 192
Query: 322 ---LGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTEL 378
LG +V+ + MG P K+ + + +LEG FR H +I ++E A + E
Sbjct: 193 YFILGTVVNKTLMG-----PIVMKL-VHQEKLEGDFRFKHMQIRVNAEPAAFYRAGHVEH 246
Query: 379 WNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIF--LQDTVSKDK 436
D RL E+ S+ L+ + Y ++ +IPIF + +S +
Sbjct: 247 MRTDRRLQRLLQ-TQRELMSKELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGDLSPAE 305
Query: 437 TAEFIT-NRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERD--- 492
+ ++ N + + S + + L + + G + R+ + + L ++ ++ +
Sbjct: 306 LSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGQLRETLLDMSLKSQDCEILG 365
Query: 493 ------DTVP----VEYDDNVIEFQNVPLITPTG-QVLISELTFKLERFNHLLIIGPNGC 541
DT P E D + V + P+ + LI +L+ K+ LLI G G
Sbjct: 366 ESEWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGT 425
Query: 542 GKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQL 601
GK+SL RVLGGLW ++ L D V +LPQ+P+ ++ T REQ+
Sbjct: 426 GKTSLLRVLGGLWTSTRGSVQML----------TDFGPHGVLFLPQKPFFTD-GTLREQV 474
Query: 602 IYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSVEDSFQ 661
IYP +K+ G+ D IL LEL L N ++A+ + V+ +
Sbjct: 475 IYP------LKEVYPDSGSADDER--ILRFLELAGLSN-----LVARTEGLDQQVDWN-- 519
Query: 662 LVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITVLS 721
W + L+ G QRL+ AR++Y +P +AVLDE TSA++ E+E ++Y+ Q LG+T +S
Sbjct: 520 ----WYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEVESELYRIGQQLGMTFIS 575
Query: 722 VCHRTTLWHFHTHLLSFDGKGNYK 745
V HR +L FH+ +L G G ++
Sbjct: 576 VGHRQSLEKFHSLVLKLCGGGRWE 599
>Hs10947127 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 563
Score = 144 bits (362), Expect = 7e-34
Identities = 138/504 (27%), Positives = 228/504 (44%), Gaps = 70/504 (13%)
Query: 268 DSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLA------ 321
D+P Q +++DV QL LI+ FTL+ F G L
Sbjct: 97 DNPDQRISQDVERFC-------RQLSSMASKLIISPFTLVYYTYQCFQSTGWLGPVSIFG 149
Query: 322 ---LGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTEL 378
LG +V+ + MG P K+ + + +LEG FR H +I ++E A + E
Sbjct: 150 YFILGTVVNKTLMG-----PIVMKL-VHQEKLEGDFRFKHMQIRVNAEPAAFYRAGHVEH 203
Query: 379 WNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIF--LQDTVSKDK 436
D RL E+ S+ L+ + Y ++ +IPIF + +S +
Sbjct: 204 MRTDRRLQRLLQ-TQRELMSKELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGDLSPAE 262
Query: 437 TAEFIT-NRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERD--- 492
+ ++ N + + S + + L + + G + R+ + + L ++ ++ +
Sbjct: 263 LSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGQLRETLLDMSLKSQDCEILG 322
Query: 493 ------DTVP----VEYDDNVIEFQNVPLITPTG-QVLISELTFKLERFNHLLIIGPNGC 541
DT P E D + V + P+ + LI +L+ K+ LLI G G
Sbjct: 323 ESEWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGT 382
Query: 542 GKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQL 601
GK+SL RVLGGLW ++ L D V +LPQ+P+ ++ T REQ+
Sbjct: 383 GKTSLLRVLGGLWTSTRGSVQML----------TDFGPHGVLFLPQKPFFTD-GTLREQV 431
Query: 602 IYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSVEDSFQ 661
IYP +K+ G+ D IL LEL L N ++A+ + V+ +
Sbjct: 432 IYP------LKEVYPDSGSADDER--ILRFLELAGLSN-----LVARTEGLDQQVDWN-- 476
Query: 662 LVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITVLS 721
W + L+ G QRL+ AR++Y +P +AVLDE TSA++ E+E ++Y+ Q LG+T +S
Sbjct: 477 ----WYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEVESELYRIGQQLGMTFIS 532
Query: 722 VCHRTTLWHFHTHLLSFDGKGNYK 745
V HR +L FH+ +L G G ++
Sbjct: 533 VGHRQSLEKFHSLVLKLCGGGRWE 556
>Hs10947129 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 447
Score = 140 bits (354), Expect = 6e-33
Identities = 131/473 (27%), Positives = 217/473 (45%), Gaps = 63/473 (13%)
Query: 299 LILCSFTLLSNANSTFMGEGTLA---------LGIIVHLSNMGLKLIQPNFTKMQMKKTQ 349
LI+ FTL+ F G L LG +V+ + MG P K+ + + +
Sbjct: 5 LIISPFTLVYYTYQCFQSTGWLGPVSIFGYFILGTVVNKTLMG-----PIVMKL-VHQEK 58
Query: 350 LEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHEIRSRALYDFATTFV 409
LEG FR H +I ++E A + E D RL E+ S+ L+ +
Sbjct: 59 LEGDFRFKHMQIRVNAEPAAFYRAGHVEHMRTDRRLQRLLQ-TQRELMSKELWLYIGINT 117
Query: 410 IKYTWGAAGLLLCSIPIF--LQDTVSKDKTAEFIT-NRRLLLTASSSIGRFVQLRRNIQQ 466
Y ++ +IPIF + +S + + ++ N + + S + + L +
Sbjct: 118 FDYLGSILSYVVIAIPIFSGVYGDLSPAELSTLVSKNAFVCIYLISCFTQLIDLSTTLSD 177
Query: 467 LQGVSLRLNKFNDELDNIINAPKERD---------DTVP----VEYDDNVIEFQNVPLIT 513
+ G + R+ + + L ++ ++ + DT P E D + V +
Sbjct: 178 VAGYTHRIGQLRETLLDMSLKSQDCEILGESEWGLDTPPGWPAAEPADTAFLLERVSISA 237
Query: 514 PTG-QVLISELTFKLERFNHLLIIGPNGCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPP 572
P+ + LI +L+ K+ LLI G G GK+SL RVLGGLW ++ L
Sbjct: 238 PSSDKPLIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQML-------- 289
Query: 573 RRNDNNESTVYYLPQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVL 632
D V +LPQ+P+ ++ T REQ+IYP +K+ G+ D IL L
Sbjct: 290 --TDFGPHGVLFLPQKPFFTD-GTLREQVIYP------LKEVYPDSGSADDER--ILRFL 338
Query: 633 ELDDLINENLSIVMAKANKKECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAV 692
EL L N ++A+ + V+ + W + L+ G QRL+ AR++Y +P +AV
Sbjct: 339 ELAGLSN-----LVARTEGLDQQVDWN------WYDVLSPGEMQRLSFARLFYLQPKYAV 387
Query: 693 LDECTSAVSPEMEQKMYKHAQDLGITVLSVCHRTTLWHFHTHLLSFDGKGNYK 745
LDE TSA++ E+E ++Y+ Q LG+T +SV HR +L FH+ +L G G ++
Sbjct: 388 LDEATSALTEEVESELYRIGQQLGMTFISVGHRQSLEKFHSLVLKLCGGGRWE 440
>Hs10947131 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 592
Score = 135 bits (339), Expect = 3e-31
Identities = 133/487 (27%), Positives = 219/487 (44%), Gaps = 70/487 (14%)
Query: 268 DSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLA------ 321
D+P Q +++DV QL LI+ FTL+ F G L
Sbjct: 140 DNPDQRISQDVERFC-------RQLSSMASKLIISPFTLVYYTYQCFQSTGWLGPVSIFG 192
Query: 322 ---LGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTEL 378
LG +V+ + MG P K+ + + +LEG FR H +I ++E A + E
Sbjct: 193 YFILGTVVNKTLMG-----PIVMKL-VHQEKLEGDFRFKHMQIRVNAEPAAFYRAGHVEH 246
Query: 379 WNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIF--LQDTVSKDK 436
D RL E+ S+ L+ + Y ++ +IPIF + +S +
Sbjct: 247 MRTDRRLQRLLQ-TQRELMSKELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGDLSPAE 305
Query: 437 TAEFIT-NRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERD--- 492
+ ++ N + + S + + L + + G + R+ + + L ++ ++ +
Sbjct: 306 LSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGQLRETLLDMSLKSQDCEILG 365
Query: 493 ------DTVP----VEYDDNVIEFQNVPLITPTG-QVLISELTFKLERFNHLLIIGPNGC 541
DT P E D + V + P+ + LI +L+ K+ LLI G G
Sbjct: 366 ESEWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGT 425
Query: 542 GKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQL 601
GK+SL RVLGGLW ++ L D V +LPQ+P+ ++ T REQ+
Sbjct: 426 GKTSLLRVLGGLWTSTRGSVQML----------TDFGPHGVLFLPQKPFFTD-GTLREQV 474
Query: 602 IYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSVEDSFQ 661
IYP +K+ G+ D IL LEL L N ++A+ + V+ +
Sbjct: 475 IYP------LKEVYPDSGSADDER--ILRFLELAGLSN-----LVARTEGLDQQVDWN-- 519
Query: 662 LVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITVLS 721
W + L+ G QRL+ AR++Y +P +AVLDE TSA++ E+E ++Y+ Q LG+T +S
Sbjct: 520 ----WYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEVESELYRIGQQLGMTFIS 575
Query: 722 VCHRTTL 728
V HR +L
Sbjct: 576 VGHRQSL 582
>CE18253 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 598
Score = 132 bits (332), Expect = 2e-30
Identities = 135/503 (26%), Positives = 216/503 (42%), Gaps = 58/503 (11%)
Query: 268 DSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLALGIIVH 327
D+P Q +T+D ++ LL + PT+ +L F + + G G+IV
Sbjct: 137 DNPDQRITQDADKLTK----LLGTSIIPTV--LLSPFIISYYGVRVWETAGGWGFGMIVA 190
Query: 328 LSNMGL---KLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELWNLDYA 384
+G+ +++ T + + EG FR H + ++EE A K E D +
Sbjct: 191 YFLIGVIINRILIGPITPWAARVEKAEGDFRYKHVSVRVNAEESAFYKSAEFEHVFSDLS 250
Query: 385 FYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIFL----QDTVSKDKTAEF 440
F L+ L + + R F +F Y G +L P+F+ + + + +
Sbjct: 251 FDVLFKRLLNFMCWRFPSQFFQSF-FDYYGGCMSYILQLFPLFVFHMYDNLTPAELSGQI 309
Query: 441 ITNRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFND----ELDNIINAPKERDDTVP 496
N + + R L NI +L G +R+++F D I N R+ +P
Sbjct: 310 SNNAFYFIYLINCFTRLTDLAMNIAELGGYIMRVSEFVDTGKLHQSGIKNEAFRRNSELP 369
Query: 497 VEY--DDNVIEFQNVPLITPTGQVL--ISELTFKLERFNHLLIIGPNGCGKSSLFRVLGG 552
+ DDN+IE +++ PT + I LTF L R LLI G +G GK+SL RV+
Sbjct: 370 EKASGDDNLIETEHLSFGPPTNSNIRIIENLTFHLPRNKTLLITGDSGIGKTSLMRVIAD 429
Query: 553 LWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMS-NKSTFREQLIYPDTLEDFI 611
+WP L + ++ Y+LPQ+PY + + ++QL++P +
Sbjct: 430 MWPHQGIL-------------KKHFKKTDAYFLPQKPYFPVGRLSLKQQLVFPAEENE-- 474
Query: 612 KKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSVEDSFQLVRPWSEELT 671
D+ ++ ILH L+L L L IV ++ DS W E L+
Sbjct: 475 -----EKSGNDEEIVRILHELKLGHL----LPIVG--------NIHDSVDF--EWQETLS 515
Query: 672 MGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITVLSVCHRTTLWHF 731
G QQRL ARM +P A LDE T V ME MY+ + IT +SV HR +L
Sbjct: 516 PGEQQRLCFARMILAEPTVAFLDESTCNVDEGMENAMYEMLRKHSITYISVGHRKSLRSH 575
Query: 732 HTHLLSFDGKGNYKFGKFNPNQR 754
H L ++ F + + NQ+
Sbjct: 576 HDFELRIPSSSSFLFHEIH-NQK 597
>At1g54350 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 680
Score = 129 bits (324), Expect = 2e-29
Identities = 137/517 (26%), Positives = 218/517 (41%), Gaps = 73/517 (14%)
Query: 260 KPEDTDLSDSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGT 319
K + + D+P Q L D+ + + + L+ T+DLI S L + F+
Sbjct: 176 KIQSQSIIDNPDQRLVDDLSSFTGTALSFSLTLVNATIDLISFSNILFTIYPPLFLVLLL 235
Query: 320 LALGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTELW 379
+ G +G L+ NF +Q KK E FR ++ ++E IA G+ E+
Sbjct: 236 YSFGGTAISVFLGKGLVNLNF--LQEKK---EADFRYSLVRVRENAESIAFYGGEQNEMQ 290
Query: 380 NLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIFLQDTVSKDKTAE 439
L F + L+ + + +F F Y + L+ +P+ + + E
Sbjct: 291 LLLQRFRSAFDNLTELLIASRNLEF---FTDGYRY-----LIQILPVAVVAPMYFSGKIE 342
Query: 440 FITNRRLLLTASSSIGRFVQLRRNIQQLQGVSL---RLNKFNDELDN-IINAPKERDDTV 495
F + + + +G F + Q + S RL +F+D LDN I P + D +
Sbjct: 343 FGVINQSVSAFNHILGDFSLVVYQFQAISSFSAVIDRLGEFDDLLDNNIFRDPSDTVDEI 402
Query: 496 PVEYDDNV-------------------IEFQNVPLITPT-GQVLISELTFKLERFNHLLI 535
+ Y + +E + + L TPT G L+ L+ + +HLLI
Sbjct: 403 ELTYQSEMNSSLLDTNGSIKSQPNQKRLEIEELTLQTPTNGTTLVHNLSADVYDKDHLLI 462
Query: 536 IGPNGCGKSSLFRVLGGLWPISKS-----LNPCLQ-TKLIMPPRRNDNNESTVYYLPQRP 589
+GP+G GK+SL R + GLW K L+P + T+ + N V +LPQRP
Sbjct: 463 MGPSGSGKTSLLRAMAGLWRSGKGKITFYLDPEVDFTQEKSDTQENSGKRGDVLFLPQRP 522
Query: 590 YMSNKSTFREQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKA 649
YM + R+QL+YP D M ++ LG H+ + ++
Sbjct: 523 YMV-LGSLRQQLLYPTW--SATPTTDDLMRTLEKVCLG--HIADRFGGLDS--------- 568
Query: 650 NKKECSVEDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMY 709
+ WS L++G QQRLA AR+ +P A+LDE TSA+ E +Y
Sbjct: 569 -------------IHEWSSVLSLGEQQRLAFARLLLSQPKLALLDESTSALDEANEAFLY 615
Query: 710 KHAQDLGITVLSVCHRTTLWHFHTHLLSF---DGKGN 743
+ Q GIT +S+ HR TL FH +L D K N
Sbjct: 616 QQIQSAGITYISIGHRRTLTKFHNKILQISTADPKSN 652
>CE05518 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 660
Score = 120 bits (301), Expect = 8e-27
Identities = 146/623 (23%), Positives = 252/623 (40%), Gaps = 136/623 (21%)
Query: 183 VLLGQWMTLGIPASIVNSLLRYMTRISAIAINRKVSDFLLDKYMASHQIFYSINNQPATH 242
++LG+ TL + +Y+T + AI +R+V + + + Q F+ +++
Sbjct: 80 IILGKAFTLAV--------FKYLTNMLAIK-SRQVCNLTMHRLYFKRQAFFKLSSSG--- 127
Query: 243 SLTLSQKSEEKSELDSDKPEDTDLSDSPVQYLTRDVGAISYNSSVLLNQLLKP--TLDLI 300
D+ D+P Q LT+D I + +L N LL P T I
Sbjct: 128 ----------------------DMLDNPDQRLTQD---IEKATRILSNDLLAPIATAPFI 162
Query: 301 LCSFTLLSNANSTFMGEGTLALGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSK 360
+ +T L+ +S ++G A+ + + K+I + ++ ++EG FR H +
Sbjct: 163 IGYYTWLTYESSGWIGPA--AIYTYFCIQTIINKMILSPIVQKVSEQEKMEGDFRQRHME 220
Query: 361 IHSSSEEIALLKGQTTELWNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLL 420
+ S+ E IA + E + L R + + T V Y G L
Sbjct: 221 VRSNVEAIAFYRAGVLENIMTNQKLKNLIETQKSLTEWRMVLNSITN-VFDYFGGILSYL 279
Query: 421 LCSIPIF---LQDTVSKDKTAEFIT-NRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNK 476
+ +P+F L D VS + ++ N L S ++L + +L GV+ R+ +
Sbjct: 280 IIGVPVFITHLYDDVSPAELNGIVSRNAFFYLYLIYSFSTVLKLTGDFGELAGVTHRVME 339
Query: 477 FNDELDNIINAPKERD---DTVP----------------------------VEYDDNVIE 505
++EL+ + + E D TVP +E D+ E
Sbjct: 340 LHEELNRLHSDCLETDRPPSTVPSSVVVIASDEDDKSASRHMQEIHGKQMSLERDEQEEE 399
Query: 506 FQNVPLITPTGQ--------------------------VLISELTFKLERFNHLLIIGPN 539
L TGQ +++ L+ ++ + LLI G +
Sbjct: 400 EAQYLLGGKTGQEDDWPDDGVAITVDSATLSPPNDHSHLIVQLLSLQIIQGQTLLITGDS 459
Query: 540 GCGKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYM-SNKSTFR 598
GCGKSSL R+ GLW S C +L S +++L Q+PY S +T R
Sbjct: 460 GCGKSSLLRMFAGLWHCSSGKMDCHWRRLT----------SNLFFLAQKPYFPSGNTTLR 509
Query: 599 EQLIYPDTLEDFIKKFDGSMGAGDQALLGILHVLELDDLINENLSIVMAKANKKECSVED 658
+Q++YP +K + IL ++++ L+ + C D
Sbjct: 510 QQIVYP------VKALQVDKDVA--RITQILEWVKMEHLV-------------ERCGGLD 548
Query: 659 SFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGIT 718
+ + W + L+ G QRL++AR++Y KP LDE TSA+ E+E +Y+ Q+ IT
Sbjct: 549 T-PVEWDWMKTLSPGELQRLSLARVFYTKPRIVFLDESTSAIGFELEMAIYRKLQEEKIT 607
Query: 719 VLSVCHRTTLWHFHTHLLSFDGK 741
+S+ HR +L FH L G+
Sbjct: 608 FVSIGHRYSLKQFHDMELRVKGR 630
>Hs18586625 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 149
Score = 97.1 bits (240), Expect = 1e-19
Identities = 49/118 (41%), Positives = 69/118 (57%), Gaps = 2/118 (1%)
Query: 666 WSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSP-EMEQKMYKHAQDLGITVLSVCH 724
W + G +QR+ MARM+YH+P + +LDECTSA +E K+++ A+D GI +LS+ H
Sbjct: 4 WKDVPPGGEKQRIGMARMFYHRPKYTLLDECTSAAMRINVEGKIFQAAKDAGIALLSITH 63
Query: 725 RTTLWHFHTHLLSFDGKGNYKFGKFNPNQRXXXXXXXXXXXXXXXQDVPIMQKRLDEL 782
R +LW +HTHLL FDG+G +KF K R +P MQ+ L EL
Sbjct: 64 RPSLWKYHTHLLQFDGEGGWKFEKLGSASRLSLTEEKQRLEQQLA-GIPKMQQHLQEL 120
>Hs10947133 [IR] KOG0060 Long-chain acyl-CoA transporter ABC superfamily
(involved in peroxisome organization and biogenesis)
Length = 497
Score = 75.9 bits (185), Expect = 2e-13
Identities = 88/360 (24%), Positives = 149/360 (40%), Gaps = 51/360 (14%)
Query: 268 DSPVQYLTRDVGAISYNSSVLLNQLLKPTLDLILCSFTLLSNANSTFMGEGTLA------ 321
D+P Q +++DV QL LI+ FTL+ F G L
Sbjct: 140 DNPDQRISQDVERFC-------RQLSSMASKLIISPFTLVYYTYQCFQSTGWLGPVSIFG 192
Query: 322 ---LGIIVHLSNMGLKLIQPNFTKMQMKKTQLEGLFRSLHSKIHSSSEEIALLKGQTTEL 378
LG +V+ + MG P K+ + + +LEG FR H +I ++E A + E
Sbjct: 193 YFILGTVVNKTLMG-----PIVMKL-VHQEKLEGDFRFKHMQIRVNAEPAAFYRAGHVEH 246
Query: 379 WNLDYAFYRLYSYLSHEIRSRALYDFATTFVIKYTWGAAGLLLCSIPIF--LQDTVSKDK 436
D RL E+ S+ L+ + Y ++ +IPIF + +S +
Sbjct: 247 MRTDRRLQRLLQ-TQRELMSKELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGDLSPAE 305
Query: 437 TAEFIT-NRRLLLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERD--- 492
+ ++ N + + S + + L + + G + R+ + + L ++ ++ +
Sbjct: 306 LSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGQLRETLLDMSLKSQDCEILG 365
Query: 493 ------DTVP----VEYDDNVIEFQNVPLITPTG-QVLISELTFKLERFNHLLIIGPNGC 541
DT P E D + V + P+ + LI +L+ K+ LLI G G
Sbjct: 366 ESEWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGT 425
Query: 542 GKSSLFRVLGGLWPISKSLNPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQL 601
GK+SL RVLGGLW ++ L D V +LPQ+P+ ++ T REQ+
Sbjct: 426 GKTSLLRVLGGLWTSTRGSVQML----------TDFGPHGVLFLPQKPFFTD-GTLREQV 474
>Hs18600750 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 118
Score = 69.3 bits (168), Expect = 2e-11
Identities = 31/69 (44%), Positives = 50/69 (71%)
Query: 657 EDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLG 716
E ++ + W + L G +QR+ MARM+ H+P +A+LDECTSAVS ++E K+++ A+D G
Sbjct: 27 EGGWEAMCDWKDVLPGGEKQRIGMARMFCHRPKYALLDECTSAVSIDVEGKIFQAAKDAG 86
Query: 717 ITVLSVCHR 725
I +LS+ H+
Sbjct: 87 IALLSITHQ 95
>Hs18574231 [I] KOG0064 Peroxisomal long-chain acyl-CoA transporter ABC
superfamily
Length = 99
Score = 68.9 bits (167), Expect = 3e-11
Identities = 32/73 (43%), Positives = 52/73 (70%)
Query: 657 EDSFQLVRPWSEELTMGIQQRLAMARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLG 716
E ++ + W + L G +QR+ MARM+YH+P +A+LDE TSAVS ++E K+++ A+D G
Sbjct: 27 EGGWEAMCDWKDILPGGEKQRIGMARMFYHRPKYALLDEGTSAVSIDVEGKIFQVAKDAG 86
Query: 717 ITVLSVCHRTTLW 729
I +LS+ + +LW
Sbjct: 87 IALLSITLQPSLW 99
>Hs9961246 [U] KOG0058 Peptide exporter ABC superfamily
Length = 703
Score = 52.4 bits (124), Expect = 3e-06
Identities = 59/242 (24%), Positives = 94/242 (38%), Gaps = 32/242 (13%)
Query: 503 VIEFQNVPLITPT--GQVLISELTFKLERFNHLLIIGPNGCGKSSLFRVLGGLWPISKSL 560
V++FQ+V P + ++ LTF L ++GPNG GKS++ +L L+ +
Sbjct: 467 VVKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLY--QPTG 524
Query: 561 NPCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGA 620
L + + + S V + Q P + + S R + Y G
Sbjct: 525 GQVLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSV-RNNIAY------------GLQSC 571
Query: 621 GDQALLGILHVLELDDLINENLSIVMAKANKKECSVEDSFQLVRPWSEELTMGIQQRLAM 680
D ++ DD I E + +K +L G +QRLA+
Sbjct: 572 EDDKVMAAAQAAHADDFIQEMEHGIYTDVGEK--------------GSQLAAGQKQRLAI 617
Query: 681 ARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDLGITVLSVCHR-TTLWHFHTHLLSFD 739
AR P +LDE TSA+ + EQ + TVL + HR + H L+ +
Sbjct: 618 ARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQAVQRAHQILVLQE 677
Query: 740 GK 741
GK
Sbjct: 678 GK 679
>7303208 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1313
Score = 52.0 bits (123), Expect = 4e-06
Identities = 62/288 (21%), Positives = 116/288 (39%), Gaps = 44/288 (15%)
Query: 447 LLTASSSIGRFVQLRRNIQQLQGVSLRLNKFNDELDNIINAPKERDDTVPVEYDDNVIEF 506
L+ ++SI + N+Q+ + + F +I++ P D + + + F
Sbjct: 1016 LIMGTASIANALAFAPNMQKGVSAAKTIFTFLRRQPSIVDRPGVSRDPW---HSEGYVRF 1072
Query: 507 QNVPLITPTGQVL--ISELTFKLERFNHLLIIGPNGCGKSSLFRVLGGLWPISKS---LN 561
V PT + + L + + + ++GP+GCGKS+ +++ + + + ++
Sbjct: 1073 DKVKFSYPTRSEIQVLKGLELAVSKGQKIALVGPSGCGKSTCIQLIQRFYDVDEGATLID 1132
Query: 562 PCLQTKLIMPPRRNDNNESTVYYLPQRPYMSNKSTFREQLIYPDTLEDFIKKFDGSMGAG 621
C + M RN + + Q P + ++ T RE + Y D +
Sbjct: 1133 ECDVRNVSMTNLRNQ-----LGIVSQEPILFDR-TIRENISYGDNARNVT---------- 1176
Query: 622 DQALLGILHVLELDDLI-NENLSIVMAKANKKECSVEDSFQLVRPWSEELTMGIQQRLAM 680
DQ ++ + + I N L K +L+ G +QR+A+
Sbjct: 1177 DQEIISACKKSNIHEFIANLPLGYDTRMGEK---------------GAQLSGGQKQRIAI 1221
Query: 681 ARMYYHKPIFAVLDECTSAVSPEMEQKMYKHAQDL---GITVLSVCHR 725
AR P +LDE TSA+ E E K+ + A D G T +S+ HR
Sbjct: 1222 ARALIRNPKIMLLDEATSALDAESE-KVVQDALDAASEGRTTISIAHR 1268
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.135 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,542,968
Number of Sequences: 60738
Number of extensions: 1738595
Number of successful extensions: 6226
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 6114
Number of HSP's gapped (non-prelim): 34
length of query: 808
length of database: 30,389,216
effective HSP length: 115
effective length of query: 693
effective length of database: 23,404,346
effective search space: 16219211778
effective search space used: 16219211778
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)