ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0707 good FE KOG1448 Amino acid transport and metabolism Ribose-phosphate pyrophosphokinase
r_klactII0707 good FE KOG1448 Nucleotide transport and metabolism Ribose-phosphate pyrophosphokinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0707 248299 249549 417
(417 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL181w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 659 0.0
SPAC4A8.14 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 389 e-108
7294893 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 233 4e-61
Hs4506127 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 230 3e-60
CE27199 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 227 2e-59
CE00745 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 227 2e-59
Hs20539448 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 227 3e-59
Hs4506129 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 226 5e-59
CE29454 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 224 1e-58
7301964 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-asso... 224 2e-58
SPCC1620.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 221 1e-57
7294894 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 220 3e-57
YBL068w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 216 5e-56
YER099c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 215 1e-55
YHL011c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 193 3e-49
SPBC3D6.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase 189 5e-48
Hs4506133 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-as... 176 8e-44
CE03789 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-asso... 171 2e-42
Hs4506131 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-as... 161 1e-39
YOL061w [FE] KOG1448 Ribose-phosphate pyrophosphokinase 159 1e-38
At2g44530 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 141 2e-33
At2g35390 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 141 2e-33
At1g32380 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 141 2e-33
Hs20542182 [FE] KOG1448 Ribose-phosphate pyrophosphokinase 60 5e-09
>YKL181w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 427
Score = 659 bits (1700), Expect = 0.0
Identities = 342/427 (80%), Positives = 368/427 (86%), Gaps = 10/427 (2%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
MRKCK+FVGNSHPELG++VC+RLGIE APCTLKKFANGETSVQIGVSVRDEDVYVIQSGS
Sbjct: 1 MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
P IND IMELLILVSACRGGSA+KITAVIPQFPYSKQCKMK+HRGAITARMLANLL+MAG
Sbjct: 61 PSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAG 120
Query: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTA 180
ADHVVSMDLHASQMQGFFTKPVDNLYGGPSL KWIRE+VEDY +AVVVSKNPGGTKRVTA
Sbjct: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTA 180
Query: 181 LADSLKINFAMIHTDRRRSKDLYSQNKDKLQLKQRKQSMLRKNKPIIRPGDFENEEENII 240
LADSLKINFAMIHTDRRRSKDLYSQNKD QLK RKQSMLRKN+PIIR GD NEEENII
Sbjct: 181 LADSLKINFAMIHTDRRRSKDLYSQNKDLQQLKLRKQSMLRKNRPIIRQGDHPNEEENII 240
Query: 241 LTNGIQTARVIKGH--XXXXXXXXXXXXIQSDGE-------GSIGTIGSFDAVDSXXXXX 291
L+NGIQTAR+ GH ++SD E S G G++DAVDS
Sbjct: 241 LSNGIQTARIRNGHVIGDDEADDDEDAILESDSELHSIDGLDSHGLGGTYDAVDSEDEEE 300
Query: 292 X-XXQPEKLITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFT 350
E+LITLVGNV+GR+AIILDDMIDRPGSFISAAEH+V+NCGAK+VYV+ATHGIFT
Sbjct: 301 IPVLYREQLITLVGNVRGRSAIILDDMIDRPGSFISAAEHLVQNCGAKKVYVVATHGIFT 360
Query: 351 GDCLEQLEMSDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVL 410
GDCLE+LE SD I +VVTNTYPIS ERI SKKLV IDVS IFAECIRRDHYGESISVL
Sbjct: 361 GDCLEELEKSDAIDTIVVTNTYPISGERIAGSKKLVTIDVSPIFAECIRRDHYGESISVL 420
Query: 411 FDSLASL 417
FDSLA+L
Sbjct: 421 FDSLAAL 427
>SPAC4A8.14 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 409
Score = 389 bits (999), Expect = e-108
Identities = 203/419 (48%), Positives = 278/419 (65%), Gaps = 22/419 (5%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M+ + G SHPEL HL+ RLGI +LK+FANGETSV+I SVRD+DV+++QSGS
Sbjct: 1 MKSATIIGGGSHPELLHLISNRLGITPCDVSLKRFANGETSVEIRESVRDKDVFILQSGS 60
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
+ND +MELLI++SAC+GGSAK+ITAV+P FPYSKQ KM+K+R AITARM+ANLL +AG
Sbjct: 61 STVNDSLMELLIIISACKGGSAKRITAVMPYFPYSKQSKMRKYRDAITARMVANLLTVAG 120
Query: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTA 180
DH++++DLHASQMQGFFT+PVDNLY P++ +WIR +V+D+ EAVVVSKNPGG KRVT+
Sbjct: 121 VDHIITLDLHASQMQGFFTRPVDNLYAEPNIAEWIRRNVDDWEEAVVVSKNPGGAKRVTS 180
Query: 181 LADSLKINFAMIHTDRRRSKDLYSQNKDKL--QLKQRKQSMLRKNKPIIRPGDFENEEEN 238
LAD+L ++FA+I+TDR+RS +D + + + + + + + RP
Sbjct: 181 LADTLNLDFALINTDRQRSSHFSQNFEDSIMDETEATETHVTNCSVYLDRP--------- 231
Query: 239 IILTNGIQTARVIKGHXXXXXXXXXX-XXIQSDGEGSIGTIGS-----FDAVDSXXXXXX 292
I TA+ + GH + S+ + S D +
Sbjct: 232 -----RIHTAKYLLGHIIDDEEIITTPASVCSEDYAQEVNLYSQGGCPSDDDEEENIMSA 286
Query: 293 XXQPEKLITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGD 352
E++ITLVG+V G+TA+++DD I+ P +FI A+EH+VK CGAK V VI THGIF
Sbjct: 287 SIYAERMITLVGDVNGKTALLIDDTIENPTAFIVASEHLVKRCGAKRVIVIGTHGIFQNK 346
Query: 353 CLEQLEMSDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
CL+ L+ + I ++VVTNTYPI + + + KL +ID+S + AE IRR H GESIS LF
Sbjct: 347 CLKDLQSCEYIEQIVVTNTYPIKPQAVLECDKLTVIDISGVLAEAIRRTHNGESISFLF 405
>7294893 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 233 bits (594), Expect = 4e-61
Identities = 107/204 (52%), Positives = 157/204 (76%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M KVF G SHP+L + +RLGI+ KKF+N ET V+IG SVR EDVY++QSGS
Sbjct: 1 MPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGS 60
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
EIND++MELLI+++AC+ SA ++TAVIP FPY++Q K K R I+A+++AN+L +AG
Sbjct: 61 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 120
Query: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTA 180
ADH+++MDLHASQ+QGFF PVDNLY P++ KWI+E++ +++ +++VS + GG KRVT+
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVTS 180
Query: 181 LADSLKINFAMIHTDRRRSKDLYS 204
+AD L + FA+IH +R+++ ++ S
Sbjct: 181 IADRLNVEFALIHKERKKANEVAS 204
Score = 90.9 bits (224), Expect = 3e-18
Identities = 50/115 (43%), Positives = 75/115 (64%), Gaps = 3/115 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+V+ + AI++DDM D G+ + AA+ +V+ GA +VY I THGIF+G + ++
Sbjct: 205 MVLVGDVKDKIAILVDDMADTCGTIVHAADRLVE-AGATKVYAILTHGIFSGPAISRINN 263
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLFDSL 414
+ VVVTNT P + +R K+ IDVS +FAE +RR H GES+S LF ++
Sbjct: 264 AC-FEAVVVTNTIP-QDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNV 316
>Hs4506127 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 230 bits (587), Expect = 3e-60
Identities = 105/202 (51%), Positives = 154/202 (75%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M K+F G+SH +L + +RLG+E KKF+N ET V+IG SVR EDVY++QSG
Sbjct: 1 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC 60
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
EIND++MELLI+++AC+ SA ++TAVIP FPY++Q K K R I+A+++AN+L +AG
Sbjct: 61 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 120
Query: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTA 180
ADH+++MDLHASQ+QGFF PVDNLY P++ KWIRE++ ++R +VS + GG KRVT+
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS 180
Query: 181 LADSLKINFAMIHTDRRRSKDL 202
+AD L ++FA+IH +R+++ ++
Sbjct: 181 IADRLNVDFALIHKERKKANEV 202
Score = 91.3 bits (225), Expect = 2e-18
Identities = 50/112 (44%), Positives = 73/112 (64%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+V+ R AI++DDM D G+ AA+ ++ + GA VY I THGIF+G + ++
Sbjct: 205 MVLVGDVKDRVAILVDDMADTCGTICHAADKLL-SAGATRVYAILTHGIFSGPAISRINN 263
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
+ VVVTNT P E++++ K+ +ID+S I AE IRR H GES+S LF
Sbjct: 264 AC-FEAVVVTNTIP-QEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 313
>CE27199 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 419
Score = 227 bits (579), Expect = 2e-59
Identities = 105/202 (51%), Positives = 158/202 (77%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M KVF G+SHP+L +CERL +E + +LKKF+N ET+V+IG SVR EDVY+IQS +
Sbjct: 101 MPNIKVFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYIIQSAA 160
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
EIND++MELLI+++AC+ S+ ++ AVIP FPY++Q K K R I+A+++AN+L +AG
Sbjct: 161 GEINDNLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAG 220
Query: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTA 180
ADH+++MDLHASQ+QGFF PVDNLY P++ K+I+E + +++ +V+VS + GG KRVT+
Sbjct: 221 ADHIITMDLHASQIQGFFDIPVDNLYAEPAILKYIKESIPNWQTSVIVSPDAGGAKRVTS 280
Query: 181 LADSLKINFAMIHTDRRRSKDL 202
+AD L ++FA+IH + +R+ ++
Sbjct: 281 IADRLNVDFALIHKESKRANEV 302
Score = 97.1 bits (240), Expect = 4e-20
Identities = 54/112 (48%), Positives = 73/112 (64%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+TLVG+V+G+ AI++DDM D G+ AA+ +V+ GA +VY HGIF+G L +L
Sbjct: 305 MTLVGSVEGKVAILVDDMADTCGTICMAADKLVE-AGADKVYAFCVHGIFSGPALTRLNA 363
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S VVVTNT P +E ++K K+ ID+S I AE IRR H GES+S LF
Sbjct: 364 SK-FEAVVVTNTIP-QDENMKKCSKIQCIDISMILAEAIRRTHNGESVSYLF 413
>CE00745 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 377
Score = 227 bits (579), Expect = 2e-59
Identities = 105/202 (51%), Positives = 158/202 (77%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M KVF G+SHP+L +CERL +E + +LKKF+N ET+V+IG SVR EDVY+IQS +
Sbjct: 59 MPNIKVFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYIIQSAA 118
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
EIND++MELLI+++AC+ S+ ++ AVIP FPY++Q K K R I+A+++AN+L +AG
Sbjct: 119 GEINDNLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAG 178
Query: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTA 180
ADH+++MDLHASQ+QGFF PVDNLY P++ K+I+E + +++ +V+VS + GG KRVT+
Sbjct: 179 ADHIITMDLHASQIQGFFDIPVDNLYAEPAILKYIKESIPNWQTSVIVSPDAGGAKRVTS 238
Query: 181 LADSLKINFAMIHTDRRRSKDL 202
+AD L ++FA+IH + +R+ ++
Sbjct: 239 IADRLNVDFALIHKESKRANEV 260
Score = 97.1 bits (240), Expect = 4e-20
Identities = 54/112 (48%), Positives = 73/112 (64%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+TLVG+V+G+ AI++DDM D G+ AA+ +V+ GA +VY HGIF+G L +L
Sbjct: 263 MTLVGSVEGKVAILVDDMADTCGTICMAADKLVE-AGADKVYAFCVHGIFSGPALTRLNA 321
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S VVVTNT P +E ++K K+ ID+S I AE IRR H GES+S LF
Sbjct: 322 SK-FEAVVVTNTIP-QDENMKKCSKIQCIDISMILAEAIRRTHNGESVSYLF 371
>Hs20539448 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 227 bits (578), Expect = 3e-59
Identities = 103/202 (50%), Positives = 153/202 (74%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M K+F G+SH +L + +RLG+E KKF+N ET V+I SVR EDVY++QSG
Sbjct: 1 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGC 60
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
EIND +MELLI+++AC+ SA ++TAVIP FPY++Q K K R I+A+++AN+L +AG
Sbjct: 61 GEINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAG 120
Query: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTA 180
ADH+++MDLHASQ+QGFF PVDNLY P++ KWIRE++ +++ ++VS + GG KRVT+
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTS 180
Query: 181 LADSLKINFAMIHTDRRRSKDL 202
+AD L ++FA+IH +R+++ ++
Sbjct: 181 IADQLNVDFALIHKERKKANEV 202
Score = 88.2 bits (217), Expect = 2e-17
Identities = 50/112 (44%), Positives = 71/112 (62%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
I LVG+V R AI++DDM D + AA+ ++ + GA VY I THGIF+G + ++
Sbjct: 205 IVLVGDVNDRVAILVDDMADTCVTICLAADKLL-SAGATRVYAILTHGIFSGPAISRINT 263
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
+ VVVTNT P +E+++ K+ +ID+S I AE IRR H GES+S LF
Sbjct: 264 AC-FEAVVVTNTIP-QDEKMKHCSKIRVIDISMILAEAIRRTHNGESVSYLF 313
>Hs4506129 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 226 bits (576), Expect = 5e-59
Identities = 103/197 (52%), Positives = 153/197 (77%)
Query: 6 VFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPEIND 65
+F G+SH +L V +RLG+E KKF+N ETSV+IG SVR EDVY+IQSG EIND
Sbjct: 6 LFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEIND 65
Query: 66 HIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGADHVV 125
++MELLI+++AC+ S+ ++TAVIP FPY++Q K K R I+A+++AN+L +AGADH++
Sbjct: 66 NLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHII 125
Query: 126 SMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALADSL 185
+MDLHASQ+QGFF PVDNLY P++ +WIRE++ +++ ++VS + GG KRVT++AD L
Sbjct: 126 TMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRL 185
Query: 186 KINFAMIHTDRRRSKDL 202
+ FA+IH +R+++ ++
Sbjct: 186 NVEFALIHKERKKANEV 202
Score = 91.7 bits (226), Expect = 2e-18
Identities = 50/112 (44%), Positives = 74/112 (65%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+V+ R AI++DDM D G+ AA+ ++ + GA +VY I THGIF+G + ++
Sbjct: 205 MVLVGDVKDRVAILVDDMADTCGTICHAADKLL-SAGATKVYAILTHGIFSGPAISRINN 263
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
+ VVVTNT P E++++ K+ +ID+S I AE IRR H GES+S LF
Sbjct: 264 AA-FEAVVVTNTIP-QEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLF 313
>CE29454 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 224 bits (572), Expect = 1e-58
Identities = 103/197 (52%), Positives = 156/197 (78%)
Query: 6 VFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPEIND 65
VF G+SHP+L +CERL +E + +LKKF+N ET+V+IG SVR EDVY+IQS + EIND
Sbjct: 5 VFSGSSHPDLSTRICERLQLEVSKASLKKFSNKETNVEIGESVRGEDVYIIQSAAGEIND 64
Query: 66 HIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGADHVV 125
++MELLI+++AC+ S+ ++ AVIP FPY++Q K K R I+A+++AN+L +AGADH++
Sbjct: 65 NLMELLIMINACKIASSCRVAAVIPAFPYARQDKKDKSRAPISAKLVANMLSVAGADHII 124
Query: 126 SMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALADSL 185
+MDLHASQ+QGFF PVDNLY P++ K+I+E + +++ +V+VS + GG KRVT++AD L
Sbjct: 125 TMDLHASQIQGFFDIPVDNLYAEPAILKYIKESIPNWQTSVIVSPDAGGAKRVTSIADRL 184
Query: 186 KINFAMIHTDRRRSKDL 202
++FA+IH + +R+ ++
Sbjct: 185 NVDFALIHKESKRANEV 201
Score = 97.1 bits (240), Expect = 4e-20
Identities = 54/112 (48%), Positives = 73/112 (64%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+TLVG+V+G+ AI++DDM D G+ AA+ +V+ GA +VY HGIF+G L +L
Sbjct: 204 MTLVGSVEGKVAILVDDMADTCGTICMAADKLVE-AGADKVYAFCVHGIFSGPALTRLNA 262
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S VVVTNT P +E ++K K+ ID+S I AE IRR H GES+S LF
Sbjct: 263 SK-FEAVVVTNTIP-QDENMKKCSKIQCIDISMILAEAIRRTHNGESVSYLF 312
>7301964 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 386
Score = 224 bits (571), Expect = 2e-58
Identities = 143/405 (35%), Positives = 220/405 (54%), Gaps = 41/405 (10%)
Query: 9 GNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPEINDHIM 68
GNSHP+L ++V ER+GI+ C++ +N ET V+I SVR +D+Y+IQ+G+ + N++IM
Sbjct: 14 GNSHPDLANMVAERMGIKNGGCSVFHKSNRETIVEISDSVRGKDIYIIQTGTKDANNNIM 73
Query: 69 ELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGADHVVSMD 128
ELLI+ AC+ SA+ I VIP PYSKQCKM+K RG I +++LA ++ +G H+++MD
Sbjct: 74 ELLIMAYACKTSSARSIVGVIPYLPYSKQCKMRK-RGCIVSKLLAKMMCTSGLTHIITMD 132
Query: 129 LHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALADSLKIN 188
LH ++QGFF PVDNL P L ++I+E + DYR +V+V++NPG K+ + A+ L++
Sbjct: 133 LHQKEIQGFFDIPVDNLRASPFLLQYIQESIPDYRNSVIVARNPGVAKKANSYAERLRLG 192
Query: 189 FAMIHTDRRRSKDLYSQNKDKLQLKQRKQSMLRKNKPIIRPGDFENEEENIILTNGI--Q 246
A+IH +++ + + ++L + + P N T+ +
Sbjct: 193 LAVIHGEQKETDADEVDGRYSPPPTSAYSNLLGNSVEMCLPATPRNSTPQHAPTSSARQR 252
Query: 247 TARVIKGHXXXXXXXXXXXXIQSDGEGSIGTIGSFDAVDSXXXXXXXXQPEKLITLVGNV 306
T V G I D G I + VD L+ +V
Sbjct: 253 TTSVSVGVPEHIVKVKPPLTIVGDVSGRIAIM-----VDD---------------LIDDV 292
Query: 307 QGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEMSDDIHKV 366
Q A AAE M+K GA ++YV+ATHG+ + D QL+ S I ++
Sbjct: 293 QAFVA---------------AAE-MLKENGACKIYVLATHGLLSSDAPRQLDES-PIDEI 335
Query: 367 VVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
VVTNT P +++ + K+ ID+S + AE IRR H ES+S LF
Sbjct: 336 VVTNTIPHEIQKL-QCHKIKTIDISILIAEAIRRIHNKESMSYLF 379
>SPCC1620.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 321
Score = 221 bits (564), Expect = 1e-57
Identities = 108/214 (50%), Positives = 154/214 (71%), Gaps = 6/214 (2%)
Query: 5 KVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPEIN 64
K+F GNSHPEL V R+G+ + +++N ETSV IG SVRDEDV+++Q+G IN
Sbjct: 7 KIFAGNSHPELAEKVARRIGLSLGKVAVVQYSNRETSVTIGESVRDEDVFILQTGCGSIN 66
Query: 65 DHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGADHV 124
DH+MELLI+++ACR SA++ITA+IP FPY++Q K K R ITAR++AN+L AG +H+
Sbjct: 67 DHLMELLIMINACRSASARRITAIIPCFPYARQDKKDKSRAPITARLVANMLQTAGCNHI 126
Query: 125 VSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVE-DYREAVVVSKNPGGTKRVTALAD 183
++MDLHASQ+QGFF PVDNLY PS+ ++IRE+++ V+VS + GG KR TALAD
Sbjct: 127 ITMDLHASQIQGFFNVPVDNLYAEPSVLRYIRENIDTTVNPTVIVSPDAGGAKRATALAD 186
Query: 184 SLKINFAMIHTDRRRSKD-----LYSQNKDKLQL 212
L ++FA+IH +R+++ + L +DKL +
Sbjct: 187 RLDLDFALIHKERQKANEVSRMVLVGDVRDKLAI 220
Score = 92.8 bits (229), Expect = 8e-19
Identities = 53/112 (47%), Positives = 75/112 (66%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+V+ + AI++DDM D G+ AA+ + N GAK VY I THGI +G ++ +
Sbjct: 208 MVLVGDVRDKLAILVDDMADTCGTLGLAAKTLKDN-GAKAVYAIVTHGILSGKAIKVINE 266
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S + KV+VTNT P ++R SK + ID+S + AECIRR H+GES+SVLF
Sbjct: 267 SA-LEKVIVTNTIPHDDKRSLCSK-IETIDISGVLAECIRRIHHGESVSVLF 316
>7294894 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 341
Score = 220 bits (560), Expect = 3e-57
Identities = 107/227 (47%), Positives = 158/227 (69%), Gaps = 23/227 (10%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M KVF G SHP+L + +RLGI+ KKF+N ET V+IG SVR EDVY++QSGS
Sbjct: 1 MPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGS 60
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGA-------------- 106
EIND++MELLI+++AC+ SA ++TAVIP FPY++Q K K G+
Sbjct: 61 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNY 120
Query: 107 ---------ITARMLANLLIMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIRE 157
I+A+++AN+L +AGADH+++MDLHASQ+QGFF PVDNLY P++ KWI+E
Sbjct: 121 DWKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKE 180
Query: 158 HVEDYREAVVVSKNPGGTKRVTALADSLKINFAMIHTDRRRSKDLYS 204
++ +++ +++VS + GG KRVT++AD L + FA+IH +R+++ ++ S
Sbjct: 181 NIPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVAS 227
Score = 90.9 bits (224), Expect = 3e-18
Identities = 50/115 (43%), Positives = 75/115 (64%), Gaps = 3/115 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+V+ + AI++DDM D G+ + AA+ +V+ GA +VY I THGIF+G + ++
Sbjct: 228 MVLVGDVKDKIAILVDDMADTCGTIVHAADRLVE-AGATKVYAILTHGIFSGPAISRINN 286
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLFDSL 414
+ VVVTNT P + +R K+ IDVS +FAE +RR H GES+S LF ++
Sbjct: 287 AC-FEAVVVTNTIP-QDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNV 339
>YBL068w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 355
Score = 216 bits (550), Expect = 5e-56
Identities = 108/200 (54%), Positives = 147/200 (73%), Gaps = 2/200 (1%)
Query: 5 KVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSG--SPE 62
K+ GNSHP+L + ++LGI + + +++N ETSV IG S+RDEDVY+IQ+G E
Sbjct: 43 KLLAGNSHPDLAEQISKKLGIPLSKVGVYQYSNKETSVTIGESLRDEDVYIIQTGIGEQE 102
Query: 63 INDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGAD 122
IND +MELLIL+ AC+ SA+KIT VIP FPY++Q K K R ITA+++ANLL AGAD
Sbjct: 103 INDFLMELLILIHACQIASARKITTVIPNFPYARQDKKDKSRAPITAKLVANLLQTAGAD 162
Query: 123 HVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALA 182
HV++MDLHASQ+QGFF PVDNLY PS+ +IR D+ A++VS + GG KRV ALA
Sbjct: 163 HVITMDLHASQIQGFFHIPVDNLYAEPSVLNYIRARKTDFDNAILVSPDAGGAKRVAALA 222
Query: 183 DSLKINFAMIHTDRRRSKDL 202
D L +NFA+IH +R+++ ++
Sbjct: 223 DKLDLNFALIHKERQKANEV 242
Score = 80.9 bits (198), Expect = 3e-15
Identities = 46/112 (41%), Positives = 70/112 (62%), Gaps = 6/112 (5%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+V ++ +++DDM D G+ + A + ++++ GAKEV I THGIF+G E+L
Sbjct: 245 MVLVGDVTNKSCLLVDDMADTCGTLVKACDTLMEH-GAKEVIAIVTHGIFSGSAREKLRN 303
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S + ++V TNT P+ + + ID+S FAE IRR H GES+S LF
Sbjct: 304 SR-LSRIVCTNTVPVDLDLPIADQ----IDISPTFAEAIRRLHNGESVSYLF 350
>YER099c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 318
Score = 215 bits (547), Expect = 1e-55
Identities = 107/200 (53%), Positives = 147/200 (73%), Gaps = 3/200 (1%)
Query: 5 KVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSG--SPE 62
K+ GNSHP L L+ +RLG+ + + +++N ETSV IG S+RDEDVY+IQ+G E
Sbjct: 7 KLLAGNSHPGLAELISQRLGVPLSKVGVYQYSNKETSVTIGESIRDEDVYIIQTGYGEHE 66
Query: 63 INDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGAD 122
IND +MELLIL+ AC+ S ++ITAVIP FPY++Q K K R ITA+++ANLL AG D
Sbjct: 67 INDFLMELLILIHACKTASVRRITAVIPNFPYARQDKKDKSRAPITAKLIANLLETAGCD 126
Query: 123 HVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALA 182
HV++MDLHASQ+QGFF PVDNLYG PS+ +IR D+ A++VS + GG KRV +LA
Sbjct: 127 HVITMDLHASQIQGFFHIPVDNLYGEPSVLNYIRTKT-DFNNAILVSPDAGGAKRVASLA 185
Query: 183 DSLKINFAMIHTDRRRSKDL 202
D L +NFA+IH +R+++ ++
Sbjct: 186 DKLDMNFALIHKERQKANEV 205
Score = 79.3 bits (194), Expect = 1e-14
Identities = 44/110 (40%), Positives = 69/110 (62%), Gaps = 6/110 (5%)
Query: 302 LVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEMSD 361
LVG+V G++ +++DDM D G+ + A + ++ + GAKEV I THGIF+G E+L ++
Sbjct: 210 LVGDVAGKSCLLIDDMADTCGTLVKACDTLMDH-GAKEVIAIVTHGIFSGSAREKL-INS 267
Query: 362 DIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
+ ++V TNT P+ + + +D+S AE IRR H GES+S LF
Sbjct: 268 RLSRIVCTNTVPVDLDLDIVDQ----VDISPTIAEAIRRLHNGESVSYLF 313
>YHL011c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 320
Score = 193 bits (491), Expect = 3e-49
Identities = 93/199 (46%), Positives = 142/199 (70%), Gaps = 2/199 (1%)
Query: 5 KVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVI-QSGSPEI 63
K+ + H L LV +RLG++ LK+ GE S IG SVRD+D+++I Q GS +
Sbjct: 7 KLLAPDVHRGLAELVAKRLGLQLTSSKLKRDPTGEVSFSIGESVRDQDIFIITQIGSGVV 66
Query: 64 NDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGADH 123
ND ++ELLI+++A + SA++ITA+IP FPY++Q + K R ITA+++A++L AG DH
Sbjct: 67 NDRVLELLIMINASKTASARRITAIIPNFPYARQDRKDKSRAPITAKLMADMLTTAGCDH 126
Query: 124 VVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALAD 183
V++MDLHASQ+QGFF PVDNLY PS+ ++I+E+V +Y +++++S + GG KR LAD
Sbjct: 127 VITMDLHASQIQGFFDVPVDNLYAEPSVVRYIKENV-NYMDSIIISPDAGGAKRAATLAD 185
Query: 184 SLKINFAMIHTDRRRSKDL 202
L +NFA+IH +R R+ ++
Sbjct: 186 RLDLNFALIHKERARANEV 204
Score = 94.0 bits (232), Expect = 4e-19
Identities = 54/112 (48%), Positives = 73/112 (64%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+V + II+DDM D G+ AAE +++N AK V I THG+ +G +E +
Sbjct: 207 MVLVGDVTDKICIIVDDMADTCGTLAKAAEILLEN-RAKSVIAIVTHGVLSGRAIENINN 265
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S + +VV TNT P EE+I+K KL +ID+SS+ AE IRR H GESIS LF
Sbjct: 266 SK-LDRVVCTNTVPF-EEKIKKCPKLAVIDISSVLAESIRRLHNGESISYLF 315
>SPBC3D6.06c [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 341
Score = 189 bits (481), Expect = 5e-48
Identities = 100/221 (45%), Positives = 140/221 (63%), Gaps = 24/221 (10%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M+ VF SHP+L +CE L ++ L KF+NGETSV+I SVR DVY++ S
Sbjct: 1 MKNLVVFGTESHPKLTESICEHLCLDIGRVELSKFSNGETSVRIKQSVRGCDVYIVSPAS 60
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQ-------------------CKMK 101
++NDH+MELLI++SAC+ SAKK+TAV+P FPYS+Q K
Sbjct: 61 GQVNDHLMELLIMISACKTASAKKVTAVLPVFPYSRQPDQKFSFSGAPLSDLQDAVVPCK 120
Query: 102 KHRG-----AITARMLANLLIMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIR 156
K G A + ++A+LL+ +GADH+++MDLH Q QGFF PVDNL+G P L +I
Sbjct: 121 KQTGYHPWIAQSGTLVADLLMCSGADHIITMDLHDPQFQGFFDIPVDNLFGRPLLKHYIS 180
Query: 157 EHVEDYREAVVVSKNPGGTKRVTALADSLKINFAMIHTDRR 197
++ +Y AV+VS + GG KR TA+AD+L ++FA+IH +RR
Sbjct: 181 LNIPNYHNAVIVSPDAGGAKRATAIADALGLDFALIHKNRR 221
Score = 92.4 bits (228), Expect = 1e-18
Identities = 52/113 (46%), Positives = 76/113 (67%), Gaps = 5/113 (4%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+ LVG+VQ + AI++DD+ID + + AAE VK GA ++Y + TH + +GD +E++++
Sbjct: 228 LMLVGDVQNKVAILIDDLIDTAYTLVRAAE-FVKEHGASKIYALVTHCVLSGDAIERVKL 286
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLFD 412
S I K++VTNT P + I S IIDV+ FAE IRR H GESIS+L+D
Sbjct: 287 SC-IDKLIVTNTAP---QTITPSGCFDIIDVAPTFAEAIRRIHNGESISILYD 335
>Hs4506133 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 369
Score = 176 bits (445), Expect = 8e-44
Identities = 90/191 (47%), Positives = 129/191 (67%), Gaps = 4/191 (2%)
Query: 6 VFVGNSHP---ELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPE 62
+F NS+ EL + ERLG+E + + N ET VQI SVR +DV++IQ+ S +
Sbjct: 22 LFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKD 81
Query: 63 INDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGAD 122
+N IMELLI+V AC+ AK I VIP FPYSKQCKM+K RG+I +++LA+++ AG
Sbjct: 82 VNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRK-RGSIVSKLLASMMCKAGLT 140
Query: 123 HVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALA 182
H+++MDLH ++QGFF PVDNL P L ++I+E + DYR AV+V+K+P KR + A
Sbjct: 141 HLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFA 200
Query: 183 DSLKINFAMIH 193
+ L++ A+IH
Sbjct: 201 ERLRLGIAVIH 211
Score = 92.0 bits (227), Expect = 1e-18
Identities = 53/115 (46%), Positives = 80/115 (69%), Gaps = 3/115 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
IT+VG+V GR AII+DD+ID SF++AAE +K GA +++V+ATHG+ + D ++E
Sbjct: 254 ITVVGDVGGRIAIIVDDIIDDVDSFLAAAE-TLKERGAYKIFVMATHGLLSSDAPRRIEE 312
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLFDSL 414
S I +VVVTNT P +++ + K+ +D+S I +E IRR H GES+S LF ++
Sbjct: 313 S-AIDEVVVTNTIPHEVQKL-QCPKIKTVDISMILSEAIRRIHNGESMSYLFRNI 365
>CE03789 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 353
Score = 171 bits (432), Expect = 2e-42
Identities = 81/196 (41%), Positives = 130/196 (66%), Gaps = 1/196 (0%)
Query: 6 VFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPEIND 65
+ GNSHPEL +V ERL I T+ N ETSV I SVR + V+++QSGS +N+
Sbjct: 13 LLTGNSHPELAKMVSERLEIRLGEATVYNKTNRETSVDIKQSVRGKHVFILQSGSKNVNN 72
Query: 66 HIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGADHVV 125
+MELL+L+ AC+ +K IT ++P PYSKQC+M + R +I +++A ++ AGA +V
Sbjct: 73 DVMELLVLIYACKTSMSKTITVIMPYLPYSKQCRMLR-RSSIAMKLVAEMICKAGASRLV 131
Query: 126 SMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALADSL 185
S+DL+ ++QGFF+ PVDNL P + I+ ++ DY+ A++V+K+PG + T+ AD L
Sbjct: 132 SLDLYKKEIQGFFSCPVDNLRASPFFLQHIKTNIPDYKNAIIVAKSPGVMNKATSYADRL 191
Query: 186 KINFAMIHTDRRRSKD 201
++ A+IH +++ ++
Sbjct: 192 RLGVAVIHGEQKDEEE 207
Score = 85.5 bits (210), Expect = 1e-16
Identities = 51/112 (45%), Positives = 75/112 (66%), Gaps = 3/112 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
+T+VG+V GR AI++DD+ID SF++AAE ++K GA ++YVIATHG+ + D LE
Sbjct: 238 LTVVGDVGGRIAIMVDDIIDDAQSFVAAAE-VLKARGAYKIYVIATHGVLSSDAPALLEA 296
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S I +V+VTNT P +++R K+ +DVS + E IRR + ES+ LF
Sbjct: 297 S-PITEVIVTNTVPHDLQKMR-CHKIKTVDVSLMICEAIRRIFHNESMGQLF 346
>Hs4506131 [EF] KOG1503 Phosphoribosylpyrophosphate synthetase-associated
protein
Length = 356
Score = 161 bits (408), Expect = 1e-39
Identities = 83/192 (43%), Positives = 125/192 (64%), Gaps = 4/192 (2%)
Query: 5 KVFVGNSHP---ELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSP 61
+VF+ NS EL + ERLG E + + NGET V+I VR +D+++IQ+
Sbjct: 9 RVFLANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKEFVRGQDIFIIQTIPR 68
Query: 62 EINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGA 121
++N +MELLI+ A + A+ I VIP FPYSKQ KM+K RG+I ++LA++L AG
Sbjct: 69 DVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRK-RGSIVCKLLASMLAKAGL 127
Query: 122 DHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTAL 181
H+++MDLH ++QGFF+ PVDNL P L ++I+E + +YR AV+V+K+P KR +
Sbjct: 128 THIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSY 187
Query: 182 ADSLKINFAMIH 193
A+ L++ A+IH
Sbjct: 188 AERLRLGLAVIH 199
Score = 91.3 bits (225), Expect = 2e-18
Identities = 52/115 (45%), Positives = 80/115 (69%), Gaps = 3/115 (2%)
Query: 300 ITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQLEM 359
IT+VG+V GR AII+DD+ID SF++AAE ++K GA ++YV+ATHGI + + +E
Sbjct: 241 ITVVGDVGGRIAIIVDDIIDDVESFVAAAE-ILKERGAYKIYVMATHGILSAEAPRLIEE 299
Query: 360 SDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLFDSL 414
S + +VVVTNT P +++ + K+ +D+S I +E IRR H GES++ LF ++
Sbjct: 300 S-SVDEVVVTNTVPHEVQKL-QCPKIKTVDISLILSEAIRRIHNGESMAYLFRNI 352
>YOL061w [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 496
Score = 159 bits (401), Expect = 1e-38
Identities = 104/306 (33%), Positives = 155/306 (49%), Gaps = 41/306 (13%)
Query: 111 MLANLLIMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSK 170
++A+LL AGADHV++MDLH Q GFF PVDNLY P +I+ + DY++AV+VS
Sbjct: 225 LIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVSP 284
Query: 171 NPGGTKRVTALADSLKINFAMIHTDRRRSKDLYSQNKDKLQLKQRKQSMLRKNKPIIRPG 230
+ GG KR TA+AD+L+++FA+IH +RR S L K P
Sbjct: 285 DAGGAKRATAIADALELSFALIHKERR--------------------SQLLKGPP----- 319
Query: 231 DFENEEENIILTNGIQTARVIKGHXXXXXXXXXXXXIQSDGEGSIGTIGSFDAVDSXXXX 290
+ LT+G + S G + + +
Sbjct: 320 -------DATLTSG---GSLPVSPRPLVTTLVSSQNTTSSGATGVAALEMKKTTSTSSTS 369
Query: 291 XXXXQPEKLI---TLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHG 347
K + LVG+V+ + II+DD++D + AA+ ++K+ G+ +VY + THG
Sbjct: 370 SQSSNSSKFVQTTMLVGDVRNKVCIIVDDLVDTSYTITRAAK-LLKDQGSTKVYALITHG 428
Query: 348 IFTGDCLEQLEMSDDIHKVVVTNTYPISEERIRKSKKLV-IIDVSSIFAECIRRDHYGES 406
+F+GD LE++ S I K++++NT P K V +IDVS I E IRR H GES
Sbjct: 429 VFSGDALERIGQS-SIDKLIISNTVPQDRTLQYLGKDRVDVIDVSCIIGEAIRRIHNGES 487
Query: 407 ISVLFD 412
IS+LF+
Sbjct: 488 ISMLFE 493
Score = 102 bits (254), Expect = 1e-21
Identities = 49/97 (50%), Positives = 68/97 (69%)
Query: 1 MRKCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
M VF G+SHPEL +CE L I + L KF+NGET++ + SVR++DVY+IQSG
Sbjct: 3 MSNIVVFGGDSHPELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYIIQSGC 62
Query: 61 PEINDHIMELLILVSACRGGSAKKITAVIPQFPYSKQ 97
++ND M+LLIL+SAC+ SA ++TAV+P YS+Q
Sbjct: 63 GQVNDTFMQLLILISACKSASASRVTAVMPYLCYSRQ 99
>At2g44530 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 386
Score = 141 bits (356), Expect = 2e-33
Identities = 74/196 (37%), Positives = 119/196 (59%), Gaps = 1/196 (0%)
Query: 3 KCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPE 62
+ ++F G ++P L + LG++ +K+FA+GE VQ+ SVR DV+++Q P
Sbjct: 77 RLRIFSGTANPILAQEISCYLGLDLGKIKIKRFADGEIYVQLQESVRGCDVFLVQPTCPP 136
Query: 63 INDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGAD 122
N+++MELL+++ ACR SAK ITAVIP F Y++ + + R +I A+++ANL+ +GAD
Sbjct: 137 ANENLMELLVMIDACRRASAKTITAVIPYFGYARADRKTQGRESIAAKLVANLITQSGAD 196
Query: 123 HVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALA 182
V++ DLH+ Q G+F PVD++YG P + ++ + VVVS + GG R A A
Sbjct: 197 RVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKAISSEDLVVVSPDVGGVARARAFA 256
Query: 183 DSLKINFAMIHTDRRR 198
L + + D+RR
Sbjct: 257 KKLS-DAPLAIVDKRR 271
Score = 68.9 bits (167), Expect = 1e-11
Identities = 39/111 (35%), Positives = 68/111 (61%), Gaps = 4/111 (3%)
Query: 298 KLITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQL 357
+++ L+G+V+G+ AI++DDMID G+ IS ++ GA+EVY TH +F+ + +L
Sbjct: 278 EVMNLIGDVKGKVAIMVDDMIDTAGT-ISKGAALLHQEGAREVYACTTHAVFSPPAISRL 336
Query: 358 EMSDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESIS 408
S +V++TNT P+SE+ +L ++ V+++ E I R H S+S
Sbjct: 337 S-SGLFQEVIITNTIPLSEKNY--FPQLTVLSVANLLGETIWRVHDDCSVS 384
>At2g35390 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 352
Score = 141 bits (356), Expect = 2e-33
Identities = 77/197 (39%), Positives = 119/197 (60%), Gaps = 1/197 (0%)
Query: 3 KCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPE 62
+ K+F G ++P L + +G++ +K+FA+GE VQ+ SVR DVY++Q
Sbjct: 41 RLKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTP 100
Query: 63 INDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGAD 122
N+++MELLI+V ACR SAKK+TAVIP F Y++ + + R +I A+++ANL+ AGAD
Sbjct: 101 TNENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGAD 160
Query: 123 HVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALA 182
V++ DLH+ Q G+F PVD++Y P + ++ + VVVS + GG R A A
Sbjct: 161 RVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPSEDLVVVSPDVGGVARARAFA 220
Query: 183 DSLKINFAMIHTDRRRS 199
L + + D+RRS
Sbjct: 221 KKLS-DAPLAIVDKRRS 236
Score = 74.7 bits (182), Expect = 2e-13
Identities = 40/114 (35%), Positives = 71/114 (62%), Gaps = 4/114 (3%)
Query: 298 KLITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQL 357
+++ L+G+V+G+ AI++DDMID G+ + A ++ GA+EVY TH +F+ +E+L
Sbjct: 242 EVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAA-LLHQEGAREVYACCTHAVFSPPAIERL 300
Query: 358 EMSDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
+ +V+VTNT P++E+ +L I+ V+++ E I R H S+S +F
Sbjct: 301 S-GGLLQEVIVTNTLPVAEKNY--FPQLTILSVANLLGETIWRVHDDSSVSSIF 351
>At1g32380 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 400
Score = 141 bits (356), Expect = 2e-33
Identities = 77/196 (39%), Positives = 119/196 (60%), Gaps = 1/196 (0%)
Query: 3 KCKVFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPE 62
K K+F G ++P L + +G+E ++K+FA+GE VQ+ SVR DV+++Q
Sbjct: 89 KLKLFSGTANPALSQEIAWYMGLELGKVSIKRFADGEIYVQLKESVRGCDVFLVQPTCTP 148
Query: 63 INDHIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAGAD 122
N+++MELLI+V ACR SAKK+TAVIP F Y++ + + R +I A+++ANL+ AGAD
Sbjct: 149 TNENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGAD 208
Query: 123 HVVSMDLHASQMQGFFTKPVDNLYGGPSLGKWIREHVEDYREAVVVSKNPGGTKRVTALA 182
V++ DLH+ Q G+F PVD++Y P + ++ + VVVS + GG R A A
Sbjct: 209 RVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSISSEDLVVVSPDVGGVARARAFA 268
Query: 183 DSLKINFAMIHTDRRR 198
L + + D+RR
Sbjct: 269 KKLS-DAPLAIVDKRR 283
Score = 74.3 bits (181), Expect = 3e-13
Identities = 39/114 (34%), Positives = 72/114 (62%), Gaps = 4/114 (3%)
Query: 298 KLITLVGNVQGRTAIILDDMIDRPGSFISAAEHMVKNCGAKEVYVIATHGIFTGDCLEQL 357
+++ L+G+V+G+ A+++DD+ID G+ + A ++ GA+EVY TH +F+ +E+L
Sbjct: 290 EVMNLIGDVKGKVAVMVDDIIDTAGTIVKGAA-LLHEEGAREVYACCTHAVFSPPAIERL 348
Query: 358 EMSDDIHKVVVTNTYPISEERIRKSKKLVIIDVSSIFAECIRRDHYGESISVLF 411
S + +V+VTNT P++E+ +L I+ V+++ E I R H S+S +F
Sbjct: 349 S-SGLLQEVIVTNTLPVAEKNY--FPQLTILSVANLLGETIWRVHDDSSVSSIF 399
>Hs20542182 [FE] KOG1448 Ribose-phosphate pyrophosphokinase
Length = 271
Score = 60.5 bits (145), Expect = 5e-09
Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 5/115 (4%)
Query: 6 VFVGNSHPELGHLVCERLGIEAAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPEIND 65
V +G+S L V +R G+E KKF+N E S+ G +RD+ YVI +IND
Sbjct: 46 VLLGSSSLGLAQKVVKRWGLELGKVVTKKFSNQEVSIVSGERMRDQAAYVI----VKIND 101
Query: 66 HIMELLILVSACRGGSAKKITAVIPQFPYSKQCKMKKHRGAITARMLANLLIMAG 120
+ L + + C+ + + AV+ PY++Q + K A++A+++AN+ +AG
Sbjct: 102 TLTS-LAMTNVCKATWSSGMKAVLSCSPYAQQDQKDKSHPAVSAKLVANVFSVAG 155
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,448,626
Number of Sequences: 60738
Number of extensions: 936646
Number of successful extensions: 2182
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2076
Number of HSP's gapped (non-prelim): 48
length of query: 417
length of database: 30,389,216
effective HSP length: 109
effective length of query: 308
effective length of database: 23,768,774
effective search space: 7320782392
effective search space used: 7320782392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)