ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0733 good U KOG2063 Intracellular trafficking, secretion, and vesicular transport Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0733 260280 257302 -993
(993 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL077c [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM... 519 e-147
7300366 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM... 136 1e-31
SPAC23H4.14 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39... 132 2e-30
Hs17478169 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/... 122 4e-27
CE18946 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM... 80 1e-14
Hs21359865 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/... 64 1e-09
At4g36630 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/V... 64 1e-09
HsM4759260 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/... 63 2e-09
>YDL077c [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 1049
Score = 519 bits (1337), Expect = e-147
Identities = 319/1037 (30%), Positives = 555/1037 (52%), Gaps = 63/1037 (6%)
Query: 1 MLTTRRISSTVLEDVQCLGRLSSWDKTVVIRKNGDFDIYTNEG-----LHTYRKLW---- 51
ML +++ S D+ + K V+ +KNGD ++Y+ +G Y L
Sbjct: 1 MLRAQKLHSLKSSDITAILPTEQSQKLVLAKKNGDVEVYSRDGNTLKLFQVYPDLLQNAK 60
Query: 52 NEP----ILDMGYSEALSTLFVQCEQSLVLFNVGNMEQYDKIIDRRGILKFWCLENRCDN 107
N+P I + ++ LST+F QC+++L+L + N+ +YD+IIDRRGI W E N
Sbjct: 61 NDPLPPVIENFYFANELSTIFAQCKETLILLSTTNLHEYDRIIDRRGINHCWLFERSHKN 120
Query: 108 EIDQKTVVVILLNTKVPRLKIFIWVSRKFSKVVEIQLSSKRETIASVALVDQGAVIATNH 167
+ ++K +I ++++ IW R + ++E LS ++ETI S+ + G +AT+
Sbjct: 121 K-EEKNTYLIYSTINTAKMRVLIWEGRTYKNMMEASLSYRKETIRSIYPGETGITLATDL 179
Query: 168 GIYIWKTGSSVLTSIDSVVTPKWSASLSASL--------KVLHNSVDGTTRNDNESLTES 219
GIY W L I+ V K+ + ++L KV+ + D +S +
Sbjct: 180 GIYHWPYNKPSLIRIEKTVKNKFPKDMISALTELKEQAEKVIEKKPKKNSHFDAQSFSSM 239
Query: 220 HTWS---SIANLWSSDRRRTRSCRALRYLFGPNHNVC--ILLDGQSQRL--LELQSSDEG 272
S S+++LW R R + +RY F + N +++DG ++++ +EL ++E
Sbjct: 240 DRMSRKSSMSSLWYRTIRNERGNK-IRYTFELDGNDATPMIIDGATKKIFKVELMHNNEE 298
Query: 273 LFYLKALPYDHFFQVNFDFNACEYLGSNFIVLYNTSTIWVVDYEQGFEYLKVRVTDGIKR 332
F + A + F + N +F+ +YL SN ++LYN+STI VDYE GF +L+ ++ +GIK
Sbjct: 299 PFLI-ATDHATFSESNSEFDHMQYLSSNLLMLYNSSTIKFVDYENGFTFLQQKIPEGIKW 357
Query: 333 VFQQSPVEIMVWTLSDVIEIYRIDVDEDL-DMKTDTLGGSMFDLNLETLEKRIVFYKSIL 391
V S +VWT +D ++++ VD+ D +++ G + D + L ++++FYK +
Sbjct: 358 VKNLSGTYFLVWTSNDEVQLFSYHVDDGSEDDDQESICGDINDPDFYQLWRKVLFYKFFI 417
Query: 392 KSNYISSMNITDDDSETRISYTMKLRDLYIVYALQIFDKAQKLHSKGEKIGLNANTTNIY 451
S + + ++D+ E+ MKLRDL +++ L+IFDK Q + E+ + +
Sbjct: 418 DSPHSKELCVSDNPEESLDICAMKLRDLTVMWCLRIFDKFQNYMVQLERSRNSRMIRSKC 477
Query: 452 EKMSYQ-IFRIFLQFLAPPVLIISFCFPDNCEIIRRKFA-------IKNQFFRETSTELS 503
E+M + IF +F++F APP L+I FP + + +K + + ++
Sbjct: 478 EEMIIKSIFDLFIKFWAPPQLVILKVFPSAISSLVLEITGQEHHCLLKEAEEVKETYDIP 537
Query: 504 AALIRKGFLPYLTETRRHVKNI-SKEKDTY----WSYNDVSLKLTLSFFESHNQAELSVA 558
L+ + LPYLT+TRRH++N+ SKE D W Y D +K + FF N ++ +
Sbjct: 538 PHLLNRWCLPYLTDTRRHLQNLLSKENDDESRITWCYRDREIKQSFDFFLISNHDDVDLN 597
Query: 559 NILTIIDTTLFEMYVKYNRSMVGPLVRVDNNCDFDTVEEILNKENMVHELIDFYYFNNEH 618
+LT+IDT LF+ Y+ YN MVGP +RV+N+CD + L +M +LIDFYY H
Sbjct: 598 TMLTLIDTVLFKCYLYYNPPMVGPFIRVENHCDSHVIVTELKIRHMFKDLIDFYYKRGNH 657
Query: 619 RKALDLLTEILDRTGD----------LKPGIKTLVIEYLKNLEFTDLDLVFQYSDYLLEK 668
+AL LT+++D + + G+K LVI YLK L LD++F Y+D+LL +
Sbjct: 658 EEALKFLTDLVDELENDNTDQKQRQKIDHGVKILVIYYLKKLSNPQLDVIFTYTDWLLNR 717
Query: 669 FPDESFDIIMLLFLRPLPFSKELDHQRIYEYIDSKRSDLSLSYLEFVVGELQSSETVIFC 728
D +I+ +F DH ++Y YI L++ YLEF + + +
Sbjct: 718 HNDSIKEILSSIFFYDSQACSSRDHLKVYGYIKKFDKLLAIQYLEFAISTFRLEGNKLHT 777
Query: 729 TLLKRYLEHINNSSTVRKLHAVLKSSKNYDAKRVLKILRNAM-NGYDNINSLELRALKYI 787
L+K YLE+++ ST KL ++L+++ Y+ + +LK+L +A+ +G D + + +L +KY+
Sbjct: 778 VLIKLYLENLDIPSTRIKLKSLLETTSVYEPRTILKLLNDAIESGSDQLPTNQLNFVKYL 837
Query: 788 TVYPINMLGDHQTALTILWGELHDYQQSSDYCNTVYQNDNDAGTLLLMEFLDKIIVFDNG 847
++P++ L +H+ A+ IL E+ DY+ ++ YCN VYQ+D+ G LL+ K++ +
Sbjct: 838 KIFPLSKLENHKEAVHILLDEIDDYKAATSYCNDVYQSDSTKGEELLLYLYSKLVSIYDS 897
Query: 848 HKKPQFLKLFLIEHGSKLQSDKVLLKLPEDMPIADLSSFFHMELKKNTAEQNQLKLLKDI 907
++ + + FL +HGSKL S ++ LP+D+ + D+ LKK+T++ ++ +L K +
Sbjct: 898 NRNSKLILNFLQDHGSKLNSAEIYKNLPQDISLYDIGRVVSQLLKKHTSKMDETRLEKAL 957
Query: 908 LYSELTKANFKLANVLSEFFIFSEERKCPICGKLLKNTSADSLAIMTYRNKTYVMYSSCA 967
L EL +KL +S + + S+ KCPIC K++ N DS++ T + + + +C
Sbjct: 958 LQVELVATTYKLNERMSSYGVLSDSHKCPICKKVISNFGTDSISWFTREGRNIITHYNCG 1017
Query: 968 KKLQAKIKHDEEPFNAK 984
K LQ E FNAK
Sbjct: 1018 KVLQ-------ERFNAK 1027
>7300366 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 876
Score = 136 bits (343), Expect = 1e-31
Identities = 118/440 (26%), Positives = 200/440 (44%), Gaps = 51/440 (11%)
Query: 556 SVANILTIIDTTLFEMYVKYNRSMVGPLVRVDNNCDFDTVEEILNKENMVHELIDFYYFN 615
S ++L IIDTTL + Y++ N S+V PL+R+ N C + E+ L K N + ELI Y
Sbjct: 456 SSKSLLEIIDTTLLKCYLQTNDSLVAPLLRL-NQCHLEESEKTLKKHNKISELIILYQMK 514
Query: 616 NEHRKALDLLTEILDRTGDLKPGIKTLVIEYLKNLEFTDLDLVFQYSDYLLEKFPDESFD 675
+H++AL LL E G + G K I YL+ L L L+F+++D++L P+E
Sbjct: 515 GKHKEALKLLREQASIEGSVLQGRKR-TIRYLQELGGDHLPLIFEFADWVLNDNPEEGLT 573
Query: 676 IIM--LLFLRPLPFSKELDHQRIYEYIDSKRSDLSLSYLEFVVGELQSSETVIFCTLLKR 733
I L+ + LP +K LD + SK L + YLE V+ E + T++ LLK+
Sbjct: 574 IFTDELIEVESLPRAKVLD------FFISKHKALVIPYLEHVITEWKDGNTLLHNVLLKQ 627
Query: 734 YLEHINNSSTVR--------------KLHAVLKSSKNYDAKRVLKILRNAMNGYDNINSL 779
Y E + + KL+ +L+ S +Y R+L+ + L
Sbjct: 628 YREKVQRLLAQQEKGEEVPELIPMRAKLYKMLEESNDYSPDRLLEEFPTNI-------LL 680
Query: 780 ELRALKYITVYPINMLGDHQTALTILWGELHDYQQSSDYCNTVYQNDNDAGTLLLMEFLD 839
E RAL + L H L+I L D +++ Y Y+ D L+ L
Sbjct: 681 EERALI------LGRLKKHDNVLSIYIHVLGDVAKATAYAEAHYKEDKHIFHTLIKCILI 734
Query: 840 KII--VFDNGHKKPQFLKL-------FLIEHGSKLQSDKVLLKLPEDMPIADLSSFFHME 890
++D P F ++ L H +++ ++ LP+DMP+ L +
Sbjct: 735 PPTQPLYDGVPLHPDFSQVNREVALEILNTHATRIDPFEIFEHLPDDMPMPQLEKYLEKS 794
Query: 891 LKKNTAEQNQLKLLKDILYSELTKANFKLANVLSEFFIFSEERKCPICGKLLKNTSADSL 950
++K A++++++++ L +E T+ L + F +E C C K + S
Sbjct: 795 IRKMMADKHEMQMMCGFLEAESTRLENALEEQRNISFELNESSVCSECKKRFQTQS---- 850
Query: 951 AIMTYRNKTYVMYSSCAKKL 970
A + Y N ++++ SC +L
Sbjct: 851 AFVRYPN-GHIVHLSCHDRL 869
>SPAC23H4.14 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 905
Score = 132 bits (333), Expect = 2e-30
Identities = 123/479 (25%), Positives = 215/479 (44%), Gaps = 53/479 (11%)
Query: 514 YLTETRRHVKNISKEKDTYWSYNDVSLKLTLSFFESHNQAELSVANILTIIDTTLFEMYV 573
YLT++RR + ++ +L L + A+ + I IDTTLF +Y+
Sbjct: 445 YLTDSRRKANRFLSYDEEHYFLQKKNLFLNA---DGTLVAKEKLEKIAVQIDTTLFLIYM 501
Query: 574 KYNRSMVGPLVRVDNNCDFDTVEEILNKENMVHELIDFYYFNNEHRKALDLLTEILDRTG 633
+ ++VG L+R+ N C+ VE L M EL+++YY + H ALDLLT++ D
Sbjct: 502 ISSPALVGSLLRLPNRCETSVVETNLLSAKMYRELVEYYYGKSLHEAALDLLTKLCDEPT 561
Query: 634 D---LKPGIKTL-----VIEYLKNLEFTDLD-LVFQYSDYLLEKFPDESFDIIMLLFLRP 684
D LK T ++ YL+ L +LD L+F+YS L + P S +++F+
Sbjct: 562 DTLSLKGKSNTTSKYEPILSYLEKLS-PELDHLIFKYSRVPLSEDPQNS----IVIFIDE 616
Query: 685 LPFSKELDHQRIYEYIDSKRSDLSLSYLEFVVGELQSSETVIFCTLLKRYLEHINN---- 740
+ + + +Y+++ +S+ YLE ++ + + ++TV L YL+ I
Sbjct: 617 NSEASTISKGVVLKYLETISYKVSIIYLEKLLLDNKFNDTVFPTRLALLYLKRILELEET 676
Query: 741 ---------SSTVRKLHAVLKSSKNYDAKRVLKILRNAMNGYDNINSLELRALKYITVYP 791
T+ KL L +SK YDA VL+ INS + L +++
Sbjct: 677 TDFKNQEVFKQTIEKLEDYLTNSKQYDANVVLQ----------EINSQD-EFLSTVSIIL 725
Query: 792 INMLGDHQTALTILWGELHDYQQSSDYCNTVYQNDNDAGTLLLMEFLDKIIVFDNGHKKP 851
L HQ AL + L+D++ + YCN+VY D + ++ + +K
Sbjct: 726 YRRLSRHQDALDVYLKILNDWEGALSYCNSVYSIDGETEPYYML-----LAEISKNYKSG 780
Query: 852 QFLKL-FLIEHGSKLQSDKVLLKLPEDMPIADLSSFFHMELKKNTAEQNQLKLLKDILYS 910
L F+ ++ S+L ++V LP+++ + S F + ++ E + + +
Sbjct: 781 SLNILDFITKYSSRLDLNRVFPLLPKNISMKSYHSLFSSQFRQLFEELSNKETQSKLYQK 840
Query: 911 ELTKANFKLANVLSEFFIFSEERKCPICGKLLKNTSADSLAIMTYRNKTYVMYSSCAKK 969
L N +L V SE + + E+ C C K L + I + + + V Y CAKK
Sbjct: 841 RLEDLNEELTKVRSEKVVITREKTCLFCHKRLGKS-----VISIFPDGSVVHY-GCAKK 893
>Hs17478169 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 886
Score = 122 bits (305), Expect = 4e-27
Identities = 121/454 (26%), Positives = 202/454 (43%), Gaps = 63/454 (13%)
Query: 556 SVANILTIIDTTLFEMYVKYNRSMVGPLVRVDNN-CDFDTVEEILNKENMVHELIDFYYF 614
S +L IIDTTL + Y+ N ++V PL+R++NN C + E +L K + ELI Y
Sbjct: 452 SKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEK 511
Query: 615 NNEHRKALDLLTEILDRTGDLKPGIKTLVIEYLKNLEFTDLDLVFQYSDYLLEKFPDESF 674
H KAL +L + + G + V +YL++L +L L+F YS ++L FP++
Sbjct: 512 KGLHEKALQVLVDQSKKANSPLKGHERTV-QYLQHLGTENLHLIFSYSVWVLRDFPEDGL 570
Query: 675 DIIMLLFLRPLPFSKELDHQRIYEYIDSKRSDLSLSYLEFVVGELQSSET-------VIF 727
I F LP + L R+ ++ L++ YLE ++ + + + ++
Sbjct: 571 KI----FTEDLPEVESLPRDRVLGFLIENFKGLAIPYLEHIIHVWEETGSRFHNCLIQLY 626
Query: 728 CT----LLKRYLEHINNSSTV--------------RKLHAVLKSSKNYDAKRVLKILRNA 769
C L+K YL T +KL L+ S YD R++
Sbjct: 627 CEKVQGLMKEYLLSFPAGKTPVPAGEEEGELGEYRQKLLMFLEISSYYDPGRLICDFP-- 684
Query: 770 MNGYDNINSLELRALKYITVYPINMLGDHQTALTILWGELHDYQQSSDYCNTVYQNDNDA 829
+D + LE RAL + +G H+ AL I L D + + +YC+ Y + D
Sbjct: 685 ---FDGL--LEERALL------LGRMGKHEQALFIYVHILKDTRMAEEYCHKHYDRNKDG 733
Query: 830 G----TLLLMEFLDKIIVFDNGHKKPQFLK--------LFLIE-HGSKLQSDKVLLKLPE 876
LL +L + G K + L+ L ++E H SKL + K L LP
Sbjct: 734 NKDVYLSLLRMYLSPPSIHCLGPIKLELLEPKANLQAALQVLELHHSKLDTTKALNLLPA 793
Query: 877 DMPIADLSSFFHMELKKNTAEQNQLKLLKDILYSELTKANFKLANVLSEFFIFSEERKCP 936
+ I D+ F L++N ++ ++LK++L++E + + I +EE+ C
Sbjct: 794 NTQINDIRIFLEKVLEENAQKKRFNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCM 853
Query: 937 ICGKLLKNTSADSLAIMTYRNKTYVMYSSCAKKL 970
+C K + N+ A Y N V Y C+K++
Sbjct: 854 VCKKKIGNS-----AFARYPNGVVVHY-FCSKEV 881
>CE18946 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 923
Score = 80.5 bits (197), Expect = 1e-14
Identities = 85/345 (24%), Positives = 149/345 (42%), Gaps = 37/345 (10%)
Query: 514 YLTETR-RHVKNISKEKDTYWSYNDVSLKLTLSFFESHNQAELSVANILTIIDTTLFEMY 572
YL+E R H K+I YN + + +A+L + L ++DTTL + Y
Sbjct: 429 YLSEIRTEHAKHIEL-------YNRLYSSGAAKKTDEDEKAKLLLT--LRVVDTTLLKCY 479
Query: 573 VKYNRSMVGPLVRVDNN-CDFDTVEEILNKENMVHELIDFYYFNNEHRKALDLLTEILDR 631
+K +V L+R+ +N C F+ ++IL E + L Y +H ALDL + R
Sbjct: 480 IKTKPMLVDSLIRLQSNACTFEDAKKILESEGRLRSLFILYETRKKHEMALDLFIDQSSR 539
Query: 632 TGDLKPGIKTL---VIEYLKNLEFTDLDLVFQYSDYLLEKFPDESFDIIMLLFLRPLPFS 688
D P ++EYL++L ++L L+ +Y+ ++L K + + + +
Sbjct: 540 P-DADPFFDDAIQQIVEYLQSLGNSNLPLILKYAKWVLAKNLEAG---VQIFTSDETEMA 595
Query: 689 KELDHQRIYEYIDSKRSDLSLSYLEFVVGELQSSETVIFCTLLKRYLEHINNSSTVRK-- 746
+ L+ + + E++ S+ D + YLE V+ + + + TLL+ Y+ +N T+ K
Sbjct: 596 RNLNRKAVVEFLKSECPDALIPYLEHVIFKWEEPSSYFHETLLEFYVARVN---TLFKDY 652
Query: 747 LHAVLKSSKNYDA-----------KRVLKILRNAMNGYDNINSLEL--RALKYITVYPIN 793
+HA A KR+LK L + + L+L A +
Sbjct: 653 VHAFPDDENITRAGDEDGELGLYRKRLLKFLEVSHSYSPQTVLLQLAPHAFYEERALILG 712
Query: 794 MLGDHQTALTILWGELHDYQQSSDYCNTVYQ-NDNDAGTLLLMEF 837
L H+ AL I L + + +YC Y +D + LM F
Sbjct: 713 RLKQHEQALAIYVNTLKNVPAAEEYCRLYYNAHDETNSQVYLMLF 757
>Hs21359865 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 860
Score = 63.9 bits (154), Expect = 1e-09
Identities = 87/400 (21%), Positives = 158/400 (38%), Gaps = 51/400 (12%)
Query: 564 IDTTLFEMYVKYNRSMVGPLVRVDNNCDFDTVEEILNKENMVHELIDFYYFNNEHRKALD 623
IDT L ++Y + + + L+ +N C L K L Y++NN+ A+
Sbjct: 448 IDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNNQDAAAVQ 507
Query: 624 LLTEILDRTGDLKPGIKTLVIEYLKNLEFTDLD--LVFQYSDYLLEKFPD---------- 671
L I++ GD++ ++ + EY+ + LD LV+ Y+D++L+K +
Sbjct: 508 LWVNIVN--GDVQDSTRSDLYEYIVDFLTYCLDEELVWAYADWVLQKSEEVGVQVFTKRP 565
Query: 672 ------ESF---DIIMLLFLRPLPFSKELDHQRIYEYIDSKR--SDLSLSYLEFVVGELQ 720
SF DII L P K L+H I + + + + L++ YLE V+ +
Sbjct: 566 LDEQQKNSFNPDDIINCLKKYPKALVKYLEHLVIDKRLQKEEYHTHLAVLYLEEVLLQRA 625
Query: 721 SSETVIFCTLLKRYLEHINNSSTVRKLHAVLKSSKNYDAKRVLKILRNAMNGYDNINSLE 780
S+ + + T KL +L+ S Y +L+ L+ A
Sbjct: 626 SASG-----------KGAEATETQAKLRRLLQKSDLYRVHFLLERLQGA----------- 663
Query: 781 LRALKYITVYPINMLGDHQTALTILWGELHDYQQSSDYCNTVYQNDNDAGTLLLMEFLDK 840
L + LG+H+ AL IL EL D+ + DYC + + L L
Sbjct: 664 --GLPMESAILHGKLGEHEKALHILVHELQDFAAAEDYCLWCSEGRDPPHRQQLFHTLLA 721
Query: 841 IIVF--DNGHKKPQFLKLFLIEHGSKLQSDKVLLKLPEDMPIADLSSFFHMELKKNTAEQ 898
I + H+ L H ++ + +VL LP+ + L F ++ + +
Sbjct: 722 IYLHAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTWSVQLLCPFLMGAMRDSIHAR 781
Query: 899 NQLKLLKDILYSELTKANFKLANVLSEFFIFSEERKCPIC 938
+++ + SE + + S+++ C IC
Sbjct: 782 RTMQVALGLARSENLIYTYDKMKLKGSSIQLSDKKLCQIC 821
>At4g36630 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 1003
Score = 63.9 bits (154), Expect = 1e-09
Identities = 63/259 (24%), Positives = 114/259 (43%), Gaps = 39/259 (15%)
Query: 583 LVRVDNNCDFDTVEEILNKENMVHELIDFYYFNNEHRKALDLLTEILD--RTGDLKPGIK 640
L++ N D EEIL K L++ + N+ H +AL LL ++ D +T + +
Sbjct: 534 LLKGVNYSDVKICEEILMKSKNYSALLELFKSNSMHHEALKLLNQLADESKTNQSQTDVT 593
Query: 641 T-----LVIEYLKNLEFTDLDLVFQYSDYLLEKFPDESFDIIMLLFLRPLPFSKELDHQR 695
L+IEYLK L TD LV +YS +LE P ++ D+ + S +
Sbjct: 594 QIFSPELIIEYLKPLCRTDPMLVLEYSMLVLESCPTQTIDLFL---------SGNISADL 644
Query: 696 IYEYIDSKRSDLSLSYLEFVVGELQSSETVIFCTLLKRYL--------EHINNSSTVRKL 747
+ Y+ ++ YLE ++ ++ + +L Y + ++ +KL
Sbjct: 645 VNSYLKQHAPNMQGRYLELMMAMNDTAVQIYLSEVLDLYAAKSAQQKWDEKDHPPERKKL 704
Query: 748 HAVLKSSKNYDAKRVLKIL-RNAMNGYDNINSLELRALKYITVYPINMLGDHQTALTILW 806
+ L+S Y + +LK L R+A+ E RA+ + + H+ AL+I
Sbjct: 705 LSALESISGYSPQPLLKRLPRDAL--------YEERAV------ILGKMNQHELALSIYV 750
Query: 807 GELHDYQQSSDYCNTVYQN 825
+LH + YC+ +Y++
Sbjct: 751 HKLHAPDLALAYCDRIYES 769
>HsM4759260 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Length = 860
Score = 63.2 bits (152), Expect = 2e-09
Identities = 87/400 (21%), Positives = 158/400 (38%), Gaps = 51/400 (12%)
Query: 564 IDTTLFEMYVKYNRSMVGPLVRVDNNCDFDTVEEILNKENMVHELIDFYYFNNEHRKALD 623
IDT L ++Y + + + L+ +N C L K L Y++NN+ A+
Sbjct: 448 IDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNNQDAAAVQ 507
Query: 624 LLTEILDRTGDLKPGIKTLVIEYLKNLEFTDLD--LVFQYSDYLLEKFPD---------- 671
L I++ GD++ ++ + EY+ + LD LV+ Y+D++L+K +
Sbjct: 508 LWVNIVN--GDVQDSTRSDLYEYIVDFLTYCLDEELVWAYADWVLQKSEEVGVQVFTKRP 565
Query: 672 ------ESF---DIIMLLFLRPLPFSKELDHQRIYEYIDSKR--SDLSLSYLEFVVGELQ 720
SF DII L P K L+H I + + + + L++ YLE V+ +
Sbjct: 566 LDEQQKNSFNPDDIINCLKKYPKALVKYLEHLVIDKRLQKEEYHTHLAVLYLEEVLLQRA 625
Query: 721 SSETVIFCTLLKRYLEHINNSSTVRKLHAVLKSSKNYDAKRVLKILRNAMNGYDNINSLE 780
S+ + + T KL +L+ S Y +L+ L+ A
Sbjct: 626 SASG-----------KGAEATETQAKLRRLLQKSDLYRVHFLLERLQGA----------- 663
Query: 781 LRALKYITVYPINMLGDHQTALTILWGELHDYQQSSDYCNTVYQNDNDAGTLLLMEFLDK 840
L + LG+H+ AL IL EL D+ + DYC + + L L
Sbjct: 664 --GLPMESAILHGKLGEHEKALHILVHELQDFAAAEDYCLWCSEGRDPPHRQQLFHTLLA 721
Query: 841 IIV--FDNGHKKPQFLKLFLIEHGSKLQSDKVLLKLPEDMPIADLSSFFHMELKKNTAEQ 898
I + H+ L H ++ + +VL LP+ + L F ++ + +
Sbjct: 722 IYLRAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTWSVQLLCPFLMGAMRDSIHAR 781
Query: 899 NQLKLLKDILYSELTKANFKLANVLSEFFIFSEERKCPIC 938
+++ + SE + + S+++ C IC
Sbjct: 782 RTMQVALGLARSENLIYTYDKMKLKGSSIQLSDKKLCQIC 821
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,070,585
Number of Sequences: 60738
Number of extensions: 2452536
Number of successful extensions: 6824
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 6787
Number of HSP's gapped (non-prelim): 15
length of query: 993
length of database: 30,389,216
effective HSP length: 116
effective length of query: 877
effective length of database: 23,343,608
effective search space: 20472344216
effective search space used: 20472344216
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)