ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0752 good J KOG2335 Translation, ribosomal structure and biogenesis tRNA-dihydrouridine synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0752 267322 266270 -351
(351 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR405w [J] KOG2335 tRNA-dihydrouridine synthase 486 e-137
SPCC777.15 [J] KOG2335 tRNA-dihydrouridine synthase 261 1e-69
Hs5902026 [J] KOG2335 tRNA-dihydrouridine synthase 221 1e-57
CE01854 [J] KOG2335 tRNA-dihydrouridine synthase 186 6e-47
7298533 [J] KOG2335 tRNA-dihydrouridine synthase 151 2e-36
At5g67220 [J] KOG2335 tRNA-dihydrouridine synthase 147 2e-35
7296234 [J] KOG2335 tRNA-dihydrouridine synthase 147 3e-35
CE09942 [J] KOG2335 tRNA-dihydrouridine synthase 134 3e-31
ECU07g1610 [J] KOG2335 tRNA-dihydrouridine synthase 128 1e-29
YML080w [J] KOG2335 tRNA-dihydrouridine synthase 117 3e-26
SPBC36B7.04 [J] KOG2335 tRNA-dihydrouridine synthase 112 1e-24
At3g49640 [J] KOG2334 tRNA-dihydrouridine synthase 107 3e-23
SPBC1709.06 [J] KOG2334 tRNA-dihydrouridine synthase 94 3e-19
CE20317 [J] KOG2334 tRNA-dihydrouridine synthase 92 1e-18
7292971 [J] KOG2334 tRNA-dihydrouridine synthase 89 7e-18
Hs8923374 [J] KOG2334 tRNA-dihydrouridine synthase 87 3e-17
YNR015w [J] KOG2334 tRNA-dihydrouridine synthase 74 3e-13
SPAC16.04 [R] KOG2333 Uncharacterized conserved protein 74 3e-13
Hs21361916 [J] KOG2335 tRNA-dihydrouridine synthase 71 3e-12
At4g38890 [R] KOG2333 Uncharacterized conserved protein 67 4e-11
YLR401c [R] KOG2333 Uncharacterized conserved protein 66 9e-11
7298625 [R] KOG2333 Uncharacterized conserved protein 66 9e-11
Hs22052882 [R] KOG2333 Uncharacterized conserved protein 65 2e-10
CE19615 [R] KOG2333 Uncharacterized conserved protein 65 2e-10
>YLR405w [J] KOG2335 tRNA-dihydrouridine synthase
Length = 367
Score = 486 bits (1250), Expect = e-137
Identities = 229/341 (67%), Positives = 278/341 (81%)
Query: 5 VQLPTAKKLTKKNDPLHIIKTRSQTHCRPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPM 64
V +P K +T++ DPLHIIKTR +TH RP TIAGPMVRYSKL FRQ CR+Y+VDIVY+PM
Sbjct: 11 VLIPKPKLITEETDPLHIIKTRQKTHGRPVTIAGPMVRYSKLPFRQLCREYNVDIVYSPM 70
Query: 65 ILAREFVRNGHARMADFTTCDEDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPI 124
ILARE+VRN HAR++D +T +ED+PLIVQVGVNNV DLLKF EMV PYCDGIGINCGCPI
Sbjct: 71 ILAREYVRNEHARISDLSTNNEDTPLIVQVGVNNVADLLKFVEMVAPYCDGIGINCGCPI 130
Query: 125 REQVREGIGSALIYNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAG 184
+EQ+REGIG ALIYN +LLC MV AVKDKY D +R+ETKIRIH+ + +TV+LC LC+AG
Sbjct: 131 KEQIREGIGCALIYNSDLLCSMVHAVKDKYGDKLRIETKIRIHEALDETVELCRKLCDAG 190
Query: 185 VDWITVHGRTRTTRSSVPVNLDAIKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVD 244
VDWIT+HGRTR TRSS P NLDAIK+I EN+ ++VP++ANGDCF L+D RI++YT
Sbjct: 191 VDWITIHGRTRRTRSSQPANLDAIKYIIENISDKNVPVIANGDCFKLSDLERITKYTGAH 250
Query: 245 GVMAVRGLLCNPALFDGYDKCPWGAVELFVHYAMQFGGLPYQLLQHHLYTMLENMGLDKL 304
GVMAVRGLL NPALF GY CPWG +E F ++A++FGGLP+QL QHHLY MLENM L K
Sbjct: 251 GVMAVRGLLSNPALFAGYTTCPWGCIEKFCYWALEFGGLPFQLAQHHLYCMLENMELKKS 310
Query: 305 LLKELMEIKNTAHLIDWLDEMFVLKRKGDPGFSKVVEMPFR 345
LLK++M +KN LIDW ++ F KR G+ GF VE+P++
Sbjct: 311 LLKKMMNLKNYISLIDWFNKTFEFKRYGEDGFGMGVEIPYK 351
>SPCC777.15 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 326
Score = 261 bits (667), Expect = 1e-69
Identities = 153/325 (47%), Positives = 204/325 (62%), Gaps = 13/325 (4%)
Query: 18 DPLHIIKTRSQTHCRPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHAR 77
DP+ I + RP IA PMVRYSKL FRQ R Y+ DIVYTPMILA+EF+ + R
Sbjct: 7 DPVKIFEINKGK--RPVHIAAPMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFL-HPKGR 63
Query: 78 MADFTTCDEDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALI 137
DF+T D D+ LI+Q GV++ L K ++V PY DGIGINCGCP ++EGIGSAL+
Sbjct: 64 YFDFSTNDADASLILQFGVDDPVILEKAAQLVGPYVDGIGINCGCPQTWAIQEGIGSALL 123
Query: 138 YNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTT 197
E + +V+AVK +S E KIRI D+ T L + ++G D ITVHGRTR
Sbjct: 124 DEPEKVHKLVRAVKSTLGESFCTEVKIRIAKDLNKTRHLMQVIEKSGADIITVHGRTRQD 183
Query: 198 RSSVPVNLDAIKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPA 257
RSS PVNLDAI+ +R ++ +P+VANGD +L I++YT+ G+M+ RGLL NPA
Sbjct: 184 RSSFPVNLDAIREVRPCVQ---IPVVANGDVKSLRKGLEIAKYTETQGIMSARGLLENPA 240
Query: 258 LFDGYDKCPWGAVELFVHYAMQFGGLPYQLLQHHLYTMLENMGLDKLLLKELMEI--KNT 315
LF GY++ PWG VE F+ Y+ + L + L HHL TM+ M +E M I +
Sbjct: 241 LFAGYEETPWGCVERFLWYSTSY-SLNFHLFYHHLTTMMGQM----TTKRERMTIPKDSF 295
Query: 316 AHLIDWLDEMFVLKRKGDPGFSKVV 340
A ++DWLDE FV++R +P F + V
Sbjct: 296 ASVMDWLDEHFVVRRPDEPMFGESV 320
>Hs5902026 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 307
Score = 221 bits (564), Expect = 1e-57
Identities = 129/313 (41%), Positives = 180/313 (57%), Gaps = 12/313 (3%)
Query: 15 KKNDPLHIIKTRSQTHCRPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNG 74
KK DP+ + + + PMVRYSKLAFR R+Y D+ YTPMI+A +FV++
Sbjct: 4 KKKDPIEMFHSGQLVK-----VCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSI 58
Query: 75 HARMADFTTCDEDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGS 134
AR ++FTT D PLIVQ N+ L +V PY +GI INCGCP R + EG G+
Sbjct: 59 KARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGA 118
Query: 135 ALIYNGELLCDMVKAVKDKYR-DSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGR 193
LI EL+ DMVK V+++ + KIRI+DD+K TV LC GV WITVHGR
Sbjct: 119 CLINKPELVQDMVKQVRNQVETPGFSVSIKIRINDDLKRTVDLCQKAEATGVSWITVHGR 178
Query: 194 TRTTRSSVPVNLDAIKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLL 253
T R PV+ D+IK I+ENM +P++ANGD +L + + T DGVM RGLL
Sbjct: 179 TAEERHQ-PVHYDSIKIIKENM---CIPVIANGDIRSLKEAENVWRITGTDGVMVARGLL 234
Query: 254 CNPALFDGYDKCPWGAVELFVHYAMQFGGLPYQLLQHHLYTMLENMGLDKLLLKELMEIK 313
NPA+F GY++ P + +V A++ G PY HL M+E + + + +
Sbjct: 235 ANPAMFAGYEETPLKCIWDWVDIALEL-GTPYMCFHQHLMYMMEKI-TSRQEKRVFNALS 292
Query: 314 NTAHLIDWLDEMF 326
+T+ +ID+L + +
Sbjct: 293 STSAIIDYLTDHY 305
>CE01854 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 290
Score = 186 bits (471), Expect = 6e-47
Identities = 102/252 (40%), Positives = 152/252 (59%), Gaps = 6/252 (2%)
Query: 46 LAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLIVQVGVNNVPDLLKF 105
LAFRQ R YDVD+ +TPMI A+ F+ + R ++ + C+ DSPLIVQ ++ L +
Sbjct: 13 LAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDPFVLSEA 72
Query: 106 TEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVKDKYRD-SVRLETKI 164
EMVY G+ +NCGCP + +G GSAL+ ELL DMV+ + + D + KI
Sbjct: 73 AEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPDPDFSVSLKI 132
Query: 165 RIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVPVNLDAIKFIRENMKYQDVPLVA 224
RI+ D++ TV LC AGV +TVHGRT + R+ P+++ A++ +++++ VP++A
Sbjct: 133 RINHDIEKTVDLCRKAEAAGVTHLTVHGRTPSQRAE-PIDIQALRIVKDSV---SVPIIA 188
Query: 225 NGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALFDGYDKCPWGAVELFVHYAMQFGGLP 284
NG T + ++E T VDG+MA GLL NPALF G++ P VE F+ + ++ GL
Sbjct: 189 NGGITTREEALFLAEQTGVDGIMAANGLLDNPALFAGHEHTPSDCVENFMRLSREY-GLD 247
Query: 285 YQLLQHHLYTML 296
+ L HL ML
Sbjct: 248 WLLYHQHLQYML 259
>7298533 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 396
Score = 151 bits (381), Expect = 2e-36
Identities = 94/304 (30%), Positives = 162/304 (52%), Gaps = 15/304 (4%)
Query: 36 IAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLIVQVG 95
++ PMVRYSKL FR+ R V + +TPM+++ + AR +F+T +D PLI Q
Sbjct: 26 VSAPMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQNEFSTGADDQPLIAQFA 85
Query: 96 VNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVKDKYR 155
+ + + +++YPY DGI +NCGCP + +G G ++ EL+ +V+ V+
Sbjct: 86 AKDPTEFVTSAQLIYPYVDGIDLNCGCPQSWAMAKGYGCGMLRQPELVHQVVQEVRRTLP 145
Query: 156 DSVRLETKIRI---HDDVKDTVKLCDDLCEAGVDWITVHGRTRTTR-SSVPVNLDAIKFI 211
+ K+R+ + ++ T+ L L AGV ++T+HGRT + S +++ A+ +
Sbjct: 146 GDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTPAQKHSKDTLDIPAMSQV 205
Query: 212 RENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALF-----DGYDKCP 266
R++++ +PL+ NG+ + D + E T GVMA RGLL NPALF DG P
Sbjct: 206 RQSLQ---IPLIVNGNVESYRDACDMHEQTGAAGVMAARGLLANPALFNSNYPDG-KTTP 261
Query: 267 WGAVELFVHYAMQFG-GLPYQLLQHHLYTMLENMGLDKLLLKELMEIKNTAHLIDWLDEM 325
V+ ++ A G L +Q HHL T + + + + L + + + ++D+L E
Sbjct: 262 LSCVQQWLDIASAAGDNLLFQCFHHHL-TFMYSAQMKRDLRVQFNSLGSKEQVVDFLKEH 320
Query: 326 FVLK 329
+ L+
Sbjct: 321 YNLE 324
>At5g67220 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 423
Score = 147 bits (371), Expect = 2e-35
Identities = 97/283 (34%), Positives = 143/283 (50%), Gaps = 23/283 (8%)
Query: 32 RPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLI 91
RP I PMV S+L FR C++Y YTPM+ +R F R +FTTC ED PL
Sbjct: 87 RPKYIVAPMVDNSELPFRLLCQKYGAQAAYTPMLHSRIFTETEKYRNQEFTTCKEDRPLF 146
Query: 92 VQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVK 151
VQ N+ LL+ + V PYCD + IN GCP R R G+ L+ N L+ +V+ +
Sbjct: 147 VQFCANDPDTLLEAAKRVEPYCDYVDINLGCPQRIARRGNYGAFLMDNLPLVKSLVEKLA 206
Query: 152 DKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVPVNLD--AIK 209
+V + KIRI +++DT+K L +AG + VHGRTR + D AIK
Sbjct: 207 QNL--NVPVSCKIRIFPNLEDTLKYAKMLEDAGCSLLAVHGRTRDEKDGKKFRADWSAIK 264
Query: 210 FIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALFDGYDKCPW-- 267
++ M+ +P++ANG+ + D + T V+GV++ LL NPA F G+ W
Sbjct: 265 EVKNAMR---IPVLANGNVRCIEDVDNCIKETGVEGVLSAETLLENPAAFAGFRTAEWAK 321
Query: 268 -GAVELFVHYAMQFGGL-------------PYQLLQHHLYTML 296
E FV + G L P+++++ H++ ML
Sbjct: 322 DNEEEGFVDGGLDQGDLVVEYLKLCEKHPVPWRMIRSHVHKML 364
>7296234 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 358
Score = 147 bits (370), Expect = 3e-35
Identities = 90/269 (33%), Positives = 139/269 (51%), Gaps = 8/269 (2%)
Query: 33 PATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLIV 92
P + PMV S+LA+R CR+Y ++ Y+PM A F + R TC ED PLI+
Sbjct: 28 PRYVVAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLII 87
Query: 93 QVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVKD 152
Q N+ +L + +CD + IN GCP R GS L ELL ++V +
Sbjct: 88 QFCGNDAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHA 147
Query: 153 KYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVP--VNLDAIKF 210
K +V + KIRI +D++ T++ L AG +TVHGRTR + + N + IK
Sbjct: 148 KL--AVPVTCKIRIFEDLEKTIRYAKMLEAAGCQLLTVHGRTREQKGPLTGVANWNYIKN 205
Query: 211 IRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALFDGYDKCPWGAV 270
+R+++K +P++ANG+ L+D +R T VDGVM+ G L NPA+F G W
Sbjct: 206 VRQHIK---IPMLANGNILALDDVHRCLTETGVDGVMSAEGNLHNPAIFKGVSPPVWQMA 262
Query: 271 ELFVHYAMQFGGLPYQLLQHHLYTMLENM 299
++ +Q P ++ HL+ + ++
Sbjct: 263 HEYLE-LVQLHPCPSSFIRGHLFKLFHHI 290
>CE09942 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 527
Score = 134 bits (336), Expect = 3e-31
Identities = 97/318 (30%), Positives = 150/318 (46%), Gaps = 8/318 (2%)
Query: 32 RPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLI 91
R + PMV S+LAFR R+Y + +TPMI A FV +G R D PL+
Sbjct: 72 RITKVLAPMVDQSELAFRMFTRKYGAQLTFTPMIHAHLFVNDGTYRRNSLALVKADRPLV 131
Query: 92 VQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVK 151
VQ N V L +V CDG+ +N GCP R GS L +L+C+MV AV+
Sbjct: 132 VQFCANKVDTFLAACRLVEDVCDGVDLNLGCPQMVAKRGRYGSWLQDEVDLICEMVSAVR 191
Query: 152 DKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVPVNLDAIKFI 211
D R + + KIR+ DD + TV+ L +AG +TVHGRTR + + L I
Sbjct: 192 DYCR--LPISCKIRVRDDRQQTVEYAKRLVDAGATMLTVHGRTRDMKGA-ETGLADWSRI 248
Query: 212 RENMKY--QDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALFDGYDK--CPW 267
R+ ++ VP++ANG+ D R + T +M+ GLL NP +FD + W
Sbjct: 249 RDVVEAVGSRVPVMANGNIQFPGDVERCMQATGAVAIMSAEGLLYNPLIFDDANAHVDTW 308
Query: 268 GAVELFVHYAMQFGGLPYQLLQHHLYTMLENMGLDKLLLKELMEIKNTAHLIDWLDEMFV 327
++ YA +F ++ H++ + + L+ L+ + +++ + + E
Sbjct: 309 KIAAEYLEYAKKFNA-GTSAIRAHVFRICHHSLLEYEDLRMRVSLEHRIEDFENIVEELA 367
Query: 328 LKRKGDPGFSKVVEMPFR 345
+ K D K E+ R
Sbjct: 368 KRAKSDAEAGKNREVEAR 385
>ECU07g1610 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 341
Score = 128 bits (322), Expect = 1e-29
Identities = 82/272 (30%), Positives = 144/272 (52%), Gaps = 10/272 (3%)
Query: 32 RPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMAD--FTTCDEDSP 89
RP PMV S+ A+R+ +++ +I YT M+ F+R + + +TT + D P
Sbjct: 10 RPYFAVAPMVGNSEEAWRRLSKRHGANIFYTEMVHCDSFLRGSRNPVKNRWYTTSEGDRP 69
Query: 90 LIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKA 149
L+VQ+ N+ +L+ ++ +CD I +N GCP + + G G+ L N +L ++VK
Sbjct: 70 LVVQICGNSPEVMLEAALIIQDHCDAIDVNFGCPQKVARKGGYGAYLQENWKLTGEIVKV 129
Query: 150 VKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVP--VNLDA 207
+ +V + KIR+ ++ TV+ + EAG + VHGRTR R + +
Sbjct: 130 LSSGL--NVPVFCKIRVFGSIEKTVEYAKMIEEAGCSLLAVHGRTRDQRGAAMGFASWKH 187
Query: 208 IKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALFDGYDKCPW 267
I+ I+EN++ +P+++NG+ T +D +R EYT DGVM L NP +F G D+
Sbjct: 188 IRAIKENLR---IPVLSNGNIMTHHDVWRCLEYTGCDGVMVGEAHLHNPLIFTGEDRSCL 244
Query: 268 GAVELFVHYAMQF-GGLPYQLLQHHLYTMLEN 298
+ ++ M+F G + ++ H++ +L N
Sbjct: 245 EIIGEYLDICMEFPGSADVRHIKSHMFRLLYN 276
>YML080w [J] KOG2335 tRNA-dihydrouridine synthase
Length = 423
Score = 117 bits (293), Expect = 3e-26
Identities = 74/234 (31%), Positives = 120/234 (50%), Gaps = 8/234 (3%)
Query: 32 RPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCD---EDS 88
RP I PMV S+LA+R R+Y + YTPM+ A+ F + R ++++ D D
Sbjct: 28 RPTRIVAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDR 87
Query: 89 PLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVK 148
PL+VQ N+ LL ++V CD + +N GCP + GS L+ +L+ +++
Sbjct: 88 PLVVQFCANDPEYLLAAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLIN 147
Query: 149 AVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVP--VNLD 206
+ + V + KIRI DD + ++ + +AG ++TVHGR R + N +
Sbjct: 148 TLHKNLK--VPVTAKIRIFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWE 205
Query: 207 AIKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALFD 260
IK++R+N+ + V ANG+ D R E+ D VM+ G L NP +F+
Sbjct: 206 TIKYLRDNLPKETV-FFANGNILYPEDISRCMEHIGADAVMSAEGNLYNPGVFN 258
>SPBC36B7.04 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 399
Score = 112 bits (279), Expect = 1e-24
Identities = 75/232 (32%), Positives = 117/232 (50%), Gaps = 7/232 (3%)
Query: 32 RPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTT--CDEDSP 89
RP I PMV S+L +R R+ D+ Y+PM +R F + R F+T E+ P
Sbjct: 17 RPKRILAPMVDQSELPWRILARRSGADLCYSPMFHSRLFGESEDYRNKVFSTRTIPEERP 76
Query: 90 LIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKA 149
LI+Q N+ +LK ++ PYCD + +N GCP + GS L N L+ ++
Sbjct: 77 LIIQFCGNDPEIMLKAAKIAAPYCDAVDVNLGCPQGIAKKGKYGSFLQENWNLIESIITK 136
Query: 150 VKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVP--VNLDA 207
+ + S+ + KIRI D + T+ + +AG + VHGR R + + +
Sbjct: 137 LHTEL--SIPVTAKIRIFPDPQKTLDYAKMILKAGASILAVHGRLREQKGHFTGIADWEQ 194
Query: 208 IKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALF 259
I+ +R+N+ + V L ANG+ D R +YT VDGV++ G L NP +F
Sbjct: 195 IQMLRKNLPSETV-LFANGNILHAQDIDRCIKYTGVDGVLSAEGSLYNPRIF 245
>At3g49640 [J] KOG2334 tRNA-dihydrouridine synthase
Length = 519
Score = 107 bits (266), Expect = 3e-23
Identities = 79/265 (29%), Positives = 122/265 (45%), Gaps = 23/265 (8%)
Query: 24 KTRSQTHCRPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMIL----------------A 67
K +++ + + PMVR L+FR +Y DI Y I+
Sbjct: 212 KKKTKMDYQNKLVLAPMVRVGTLSFRMLAAEYGADITYGEEIIDHKLVKCERRLNVASGT 271
Query: 68 REFVRNGHARMADFTTCDED-SPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIRE 126
EFV G + F+TCDE+ S ++ Q+G ++ LK +E+V I IN GCP
Sbjct: 272 SEFVEKGTDNVV-FSTCDEEKSRVVFQMGTSDAVRALKASEIVCNDVATIDINMGCPKAF 330
Query: 127 QVREGIGSALIYNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVD 186
++ G+G+AL+ EL+ D++ +K V + KIR+ DTV+L + + GV
Sbjct: 331 SIQGGMGAALLSKPELIHDILATLKRNL--DVPVTCKIRLLKSPADTVELARRIEKLGVP 388
Query: 187 WITVHGRTRTTRSSVPVNLDAIKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGV 246
+ VHGR R P D I + + +P++ANGD +D RI T V
Sbjct: 389 ALAVHGRKIADRPRDPAKWDEIADV---VAALSIPVIANGDVLEYDDFSRIKTATGAASV 445
Query: 247 MAVRGLLCNPALFDGYDKCPWGAVE 271
M RG + N ++F K W V+
Sbjct: 446 MVARGAMWNASIFSPKGKSHWEDVK 470
>SPBC1709.06 [J] KOG2334 tRNA-dihydrouridine synthase
Length = 479
Score = 94.0 bits (232), Expect = 3e-19
Identities = 69/242 (28%), Positives = 114/242 (46%), Gaps = 21/242 (8%)
Query: 39 PMVRYSKLAFRQTCRQYDVDIVYTPMILAR--------EFVRNGHARMADFTTCD----- 85
PMVR +L R +Y ++V+ P I+ + E V N DF
Sbjct: 14 PMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCIDFVKPPSNKVL 73
Query: 86 ------EDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYN 139
E + LI Q+G + ++ ++V GI +NCGCP V G+G+ L+ N
Sbjct: 74 FRVHPLEANRLIFQLGSASPELAVEAAKLVANDVAGIDLNCGCPKHFSVHAGMGAGLLKN 133
Query: 140 GELLCDMVKAVKDKYRD--SVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTT 197
+ L ++ A+ ++ + + KIR+ + +DT+KL + +C+ GV ITVH RT
Sbjct: 134 QDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERICDTGVRAITVHCRTTPM 193
Query: 198 RSSVPVNLDAIKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPA 257
R++ P + + I + +DV ++ NGD + ND + E VDGV+ R N +
Sbjct: 194 RNTEPADRSYLSEIVGVCRNKDVSILVNGDVLSYNDGLDVIEKYGVDGVLIARAAERNVS 253
Query: 258 LF 259
F
Sbjct: 254 CF 255
>CE20317 [J] KOG2334 tRNA-dihydrouridine synthase
Length = 436
Score = 92.0 bits (227), Expect = 1e-18
Identities = 66/245 (26%), Positives = 113/245 (45%), Gaps = 21/245 (8%)
Query: 32 RPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVR-----NGHARMADFTTCD- 85
R I PMVR + R C +Y D+ YT I+ ++ + N D+ D
Sbjct: 6 RNKKILAPMVRAGRTPLRLLCLKYGADLCYTEEIVDKKLIEATRVVNEALGTIDYRNGDD 65
Query: 86 --------EDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALI 137
E I+Q+G N+ K ++V GI +N GCP + G+G+AL+
Sbjct: 66 IILRLAPEEKGRCILQIGTNSGEKAAKIAQIVGDDVAGIDVNMGCPKPFSIHCGMGAALL 125
Query: 138 YNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTT 197
E + D++ ++K + V + KIR+ DD +DT+KL ++ + V + VHGR R
Sbjct: 126 TQTEKIVDILTSLKSAAK--VPVTCKIRVLDDPEDTLKLVQEIEKCRVSALGVHGRRRDE 183
Query: 198 RSSVPVNLDAIKFIRENMKYQDVPLVANG---DCFTLNDCYRISEYTKVDGVMAVRGLLC 254
R +D I+ + + + Q +P+++NG + +D + T+ M R L
Sbjct: 184 RQPDKCRIDEIRDVAQAV--QSIPVISNGLSDEIEQYSDFEKYQLLTETSSTMIARKALS 241
Query: 255 NPALF 259
P++F
Sbjct: 242 TPSIF 246
>7292971 [J] KOG2334 tRNA-dihydrouridine synthase
Length = 460
Score = 89.4 bits (220), Expect = 7e-18
Identities = 69/283 (24%), Positives = 125/283 (43%), Gaps = 25/283 (8%)
Query: 23 IKTRSQTHCRPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRN--------G 74
+KTR + R I PMVR L R + DIVYT ++ + +++ G
Sbjct: 1 MKTRQRLDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALG 60
Query: 75 HARMAD-------FTTC-DEDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIRE 126
D F TC E S L++Q+G ++ L +++ G+ IN GCP
Sbjct: 61 TVDFVDPSDGTIVFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEF 120
Query: 127 QVREGIGSALIYNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVD 186
++ G+G+AL+ + + +++ + + + KIRI DV+ T+ L L G+
Sbjct: 121 SIKGGMGAALLADPDKAAHILRTLCSGL--DIPVTCKIRILPDVEGTIDLVQKLAATGIA 178
Query: 187 WITVHGRTRTTRSSVPVNLDAIKFIRENMKYQDVPLVANG---DCFTLNDCYRISEYTKV 243
I +H RTR R P + + ++ + + + D+P++ANG + +D +
Sbjct: 179 AIGIHARTRDERPQHPAHPEVLRAVAQAV---DIPIIANGGSKNMHCYDDLRKFQMECGA 235
Query: 244 DGVMAVRGLLCNPALFDGYDKCPWG-AVELFVHYAMQFGGLPY 285
D VM R N ++F P +E ++ + + P+
Sbjct: 236 DSVMVARAAQINVSIFRPEGLLPMDELIEKYLRLCVDYDNAPH 278
>Hs8923374 [J] KOG2334 tRNA-dihydrouridine synthase
Length = 493
Score = 87.4 bits (215), Expect = 3e-17
Identities = 71/265 (26%), Positives = 118/265 (43%), Gaps = 25/265 (9%)
Query: 36 IAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVR-----NGHARMADFT-------- 82
I PMVR L R Y DIVY ++ + ++ N DF
Sbjct: 15 ILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDDRVVF 74
Query: 83 -TCD-EDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIGSALIYNG 140
TC+ E + ++ Q+G ++ L +V GI +N GCP + + G+G+AL+ +
Sbjct: 75 RTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKGGMGAALLSDP 134
Query: 141 ELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSS 200
+ + ++ + R V KIRI ++DT+ L + G+ I VHGR R R
Sbjct: 135 DKIEKILSTLVKGTRRPVTC--KIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREERPQ 192
Query: 201 VPVNLDAIKFIRENMKYQDVPLVANGDCF----TLNDCYRISEYTKVDGVMAVRGLLCNP 256
PV+ + IK I + + +P++ANG +D + T VM R + NP
Sbjct: 193 HPVSCEVIKAIADTL---SIPVIANGGSHDHIQQYSDIEDFRQATAASSVMVARAAMWNP 249
Query: 257 ALFDGYDKCPWGAV-ELFVHYAMQF 280
++F P V + ++ YA+Q+
Sbjct: 250 SIFLKEGLRPLEEVMQKYIRYAVQY 274
>YNR015w [J] KOG2334 tRNA-dihydrouridine synthase
Length = 384
Score = 73.9 bits (180), Expect = 3e-13
Identities = 60/217 (27%), Positives = 93/217 (42%), Gaps = 28/217 (12%)
Query: 36 IAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCD---------- 85
+ PMVR +L R + D+V++P I+ ++ ++ T D
Sbjct: 9 VLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCVRKENTALQTVDYVVPSKVQTR 68
Query: 86 ------------EDSPLIVQVGVNNVPDLLKFTEMVYPYCDGIGINCGCPIREQVREGIG 133
E S LI Q+G + + V GI IN GCP + G+G
Sbjct: 69 PETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMG 128
Query: 134 SALIYNGELLC----DMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWIT 189
SAL+ + LC ++VK V + + S + KIR+ D +DT++L LC G+ +T
Sbjct: 129 SALLRTPDTLCLILKELVKNVGNPH--SKPISVKIRLLDTKQDTLQLVKRLCATGITNLT 186
Query: 190 VHGRTRTTRSSVPVNLDAIKFIRENMKYQDVPLVANG 226
VH R R+ D I I E + +V L+ NG
Sbjct: 187 VHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNG 223
>SPAC16.04 [R] KOG2333 Uncharacterized conserved protein
Length = 617
Score = 73.9 bits (180), Expect = 3e-13
Identities = 71/295 (24%), Positives = 120/295 (40%), Gaps = 40/295 (13%)
Query: 1 MSLSVQLPTAKKLTKKNDPLHIIKTRSQT--HCRPATIAGPMVRYSKLAFRQTCRQYDVD 58
+S++V L + N L ++ + + R I P+ FR+ C D
Sbjct: 205 VSVNVDLKEISSQARSNIALPTLRPQEKNLIDWRDRKILAPLTTVGNPPFRRLCGSLGAD 264
Query: 59 IVYTPMILAREFVRNGHARMADFTTCDEDSPLI---------VQVGVNNVPDLLKFTEMV 109
Y+ M + ++ A + + ++ VQ+ + K +++
Sbjct: 265 TFYSEMAMCYPLMQGHQPEWALVRGLNYEREMMRGGRRGILGVQLATGKLWQATKTAQVI 324
Query: 110 YPYCDGIG---INCGCPIREQVREGIGSALIYN-GELLCDMVKAVKDKYRDSVRLETKIR 165
CDG+ +NCGCPI R+G GS+L+ N G LL ++ D + + K+R
Sbjct: 325 AEQCDGVDFLDLNCGCPIDLVFRQGAGSSLLENPGRLLRNL--QGMDAVSGQIPVTVKLR 382
Query: 166 I-----HDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVPVNLDAIKFI--------- 211
+ H VK+ + + E T+HGR+R R S N D I I
Sbjct: 383 MGNKDDHPVVKNLIGRIFN--ETNTSAATLHGRSRQQRYSKNANWDYIGEIASKVKSMNE 440
Query: 212 ------RENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALFD 260
++++ Q + L+ NGDC++ D Y VD VM RG L P +F+
Sbjct: 441 RIDELPEDSLRTQPLSLIGNGDCYSWQDWYD-GVNKGVDTVMIARGALVKPWIFE 494
>Hs21361916 [J] KOG2335 tRNA-dihydrouridine synthase
Length = 363
Score = 70.9 bits (172), Expect = 3e-12
Identities = 55/184 (29%), Positives = 92/184 (49%), Gaps = 9/184 (4%)
Query: 133 GSALIYNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHG 192
G+ L +LL M+ +K SV + KIR+ ++ TV+ L +AG +TVHG
Sbjct: 9 GAFLQDEWDLLQRMILLAHEKL--SVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHG 66
Query: 193 RTRTTRS--SVPVNLDAIKFIRENMKYQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVR 250
RT+ + S + + IK +R+ + +P+ ANG+ L D R T V GVM+
Sbjct: 67 RTKEQKGPLSGAASWEHIKAVRKAVA---IPVFANGNIQCLQDVERCLRDTGVQGVMSAE 123
Query: 251 GLLCNPALFDGYDKCPWGAVELFVHYAMQFGGLPYQLLQHHLYTMLEN-MGLDKLLLKEL 309
G L NPALF+G W E ++ + P ++ HL+ + + + + + L +EL
Sbjct: 124 GNLHNPALFEGRSPAVWELAEEYLDIVREH-PCPLSYVRAHLFKLWHHTLQVHQELREEL 182
Query: 310 MEIK 313
++K
Sbjct: 183 AKVK 186
>At4g38890 [R] KOG2333 Uncharacterized conserved protein
Length = 700
Score = 67.0 bits (162), Expect = 4e-11
Identities = 58/266 (21%), Positives = 106/266 (39%), Gaps = 15/266 (5%)
Query: 8 PTAKKLTKKNDPLHIIKTRSQTHCRPAT-----------IAGPMVRYSKLAFRQTCRQYD 56
PT+K + D + I++T S P P+ L FR+ C+
Sbjct: 311 PTSKANVEDEDSIKIVETDSSLKLHPREKKKLIDFRDKLYLAPLTTVGNLPFRRLCKVLG 370
Query: 57 VDIVYTPMILAREFVRNGHARMADFTTCDEDSPLIVQVGVNNVPDLLKFTEMVYPYC--D 114
D+ M + ++ + A + VQ+ + + + E++ C D
Sbjct: 371 ADVTCGEMAMCTNLLQGQASEWALLRRHSSEDLFGVQICGSYPDTVSRVVELIDRECTVD 430
Query: 115 GIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTV 174
I IN GCPI V + GSAL+ + ++V+ + ++ + +
Sbjct: 431 FIDINMGCPIDMVVNKSAGSALLNKPLRMKNIVEVSSSIVETPITIKVRTAFFEGKNRID 490
Query: 175 KLCDDLCEAGVDWITVHGRTRTTRSSVPVNLDAIKFIRENMKYQDVPLVANGDCFTLNDC 234
L D+ G +T+HGR+R R S + D I +N ++ ++ NGD ++ D
Sbjct: 491 SLIADIGNWGATAVTIHGRSRQQRYSKSADWDYIYQCTKNAT-TNLQVIGNGDVYSYLDW 549
Query: 235 YR-ISEYTKVDGVMAVRGLLCNPALF 259
+ S+ ++ M RG L P +F
Sbjct: 550 NKHKSDCPELSSCMIARGALIKPWIF 575
>YLR401c [R] KOG2333 Uncharacterized conserved protein
Length = 609
Score = 65.9 bits (159), Expect = 9e-11
Identities = 60/253 (23%), Positives = 102/253 (39%), Gaps = 31/253 (12%)
Query: 36 IAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLI-VQV 94
I P+ L +R+ R+ D+ Y+ M LA ++ ++ A + P VQV
Sbjct: 296 IVSPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTNSEWALPKAHTSEFPGFGVQV 355
Query: 95 GVNNVPDLLKFTEMV---YPYCDGIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVK 151
+ K E + I +N GCPI R+G GSAL+ N + + A+
Sbjct: 356 ACSKAWQAAKAAEALANSVSEISEINLNSGCPIDLLYRQGSGSALLDNPARMIRCLNAMN 415
Query: 152 DKYRDSVRLETKIRIHDDVKDTVKLCDDLC-----EAGVDWITVHGRTRTTRSSVPVNLD 206
+D + ++I K+ + + L E V IT+HGR+R R + + D
Sbjct: 416 YVSKD---IPITVKIRTGTKEGHPIAEGLVKRLVNETDVAAITLHGRSRQQRYTKSADWD 472
Query: 207 AIKFIRENMKYQD------------------VPLVANGDCFTLNDCYR-ISEYTKVDGVM 247
+ + + ++ + + V NGD D YR ++ +D VM
Sbjct: 473 YVSQVADTLRSAEADFIETEQGKEGRDSKNRIQFVGNGDVNNFEDWYRYLNGNENIDSVM 532
Query: 248 AVRGLLCNPALFD 260
RG L P +F+
Sbjct: 533 VARGALIKPWIFE 545
>7298625 [R] KOG2333 Uncharacterized conserved protein
Length = 604
Score = 65.9 bits (159), Expect = 9e-11
Identities = 72/278 (25%), Positives = 117/278 (41%), Gaps = 21/278 (7%)
Query: 32 RPATIAGPMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLI 91
R + P+ L FR+ C+++ DI M A+ ++ A +
Sbjct: 256 REKLVLSPLTTLGNLPFRRICKEFGADITCGEMACAQPLLKGMGQEWALTKRHQSEDVFG 315
Query: 92 VQVGVNNVPDLLKFTEMVYPYC--DGIGINCGCPIREQVREGIGSALIYNGELLCDMVK- 148
VQ+ NN L + ++++ D I +N GCPI ++G GSAL+ +L V+
Sbjct: 316 VQLCGNNPNMLNQAAQVIHETAQVDFIDLNIGCPIDLIYQQGGGSALMRRTNILELTVRS 375
Query: 149 --AVKDKYRDSVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVPVNLD 206
A+ D+ +V++ T I+ D +L + E G +T+HGR+R R + N
Sbjct: 376 CAALSDRLPFTVKMRT--GIYADKSVAHELLPLVEEWGASAVTLHGRSREQRYTKHANWA 433
Query: 207 AIKFIRENMKYQDVPLVANGDCFTLND-CYRISEYTKVDGVMAVRGLLCNPALFDGY-DK 264
I+ K +P++ NGD + D R + V VM RG L P +F +K
Sbjct: 434 YIEECAAKAKC--MPVIGNGDILSYEDYMERRTLAPHVCSVMIGRGALIKPWIFQEIKEK 491
Query: 265 CPWGAVELFVHYAMQFGGLPYQLLQHHLYTMLENMGLD 302
W G Y++LQ LE+ G D
Sbjct: 492 QAWS----------PSSGQRYEMLQKFCNYGLEHWGSD 519
>Hs22052882 [R] KOG2333 Uncharacterized conserved protein
Length = 650
Score = 64.7 bits (156), Expect = 2e-10
Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 7/224 (3%)
Query: 39 PMVRYSKLAFRQTCRQYDVDIVYTPMILAREFVRNGHARMADFTTCDEDSPLIVQVGVNN 98
P+ L FR+ C+++ D+ M + ++ + A + VQ+
Sbjct: 311 PLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGAF 370
Query: 99 VPDLLKFTEMVYPYC--DGIGINCGCPIREQVREGIGSALIYNGELLCDMVKAVKDKYRD 156
+ K E++ D + IN GCPI ++G G AL+ +V+ +
Sbjct: 371 PDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLDV 430
Query: 157 SVRLETKIRIHDDVKDTVKLCDDLCEAGVDWITVHGRTRTTRSSVPVNLDAIKFIRENMK 216
+ ++ + + + V +L +L + GV +T+HGR+R R + L ++I E ++
Sbjct: 431 PLTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYT---KLADWQYIEECVQ 487
Query: 217 -YQDVPLVANGDCFTLNDCYRISEYTKVDGVMAVRGLLCNPALF 259
+PL NGD + D R + T V G+M RG L P LF
Sbjct: 488 AASPMPLFGNGDILSFEDANRAMQ-TGVTGIMIARGALLKPWLF 530
>CE19615 [R] KOG2333 Uncharacterized conserved protein
Length = 554
Score = 64.7 bits (156), Expect = 2e-10
Identities = 71/271 (26%), Positives = 108/271 (39%), Gaps = 19/271 (7%)
Query: 3 LSVQLPTAKKLTKKNDPLHIIKTRSQTHCRPATIAGPMVRYSKLAFRQTCRQYDVDIVYT 62
L + L T + ++ PL++ + + P T G L FR+ C Y DI
Sbjct: 180 LELSLSTVGAMCREKKPLNMGSLDGKKYLAPLTTVG------NLPFRRICVDYGADITCG 233
Query: 63 PMILAREFVRNGHARMADFTTCDEDSPLIVQVGVNNVPDLLKFTEMVYPY--CDGIGINC 120
M LA + + + + VQ+ + K +++V D I IN
Sbjct: 234 EMALATSILSGTASEYSLLKRHPCEKIFGVQLAGGFADTMAKASQIVVENFDVDFIDINM 293
Query: 121 GCPIREQVREGIGSALIYNGELLCDMVKAVKDKYRDSVRLETKIRIHDDVKDTVKLCDDL 180
GCPI ++G G AL + L +++ A K L KIR +K+ V +
Sbjct: 294 GCPIDVVNQKGGGCALPSRPQKLFEVLAATKSVLGGCCPLTVKIRT--GMKEGVLKAPEY 351
Query: 181 CEA-------GVDWITVHGRTRTTRSSVPVNLDAIKFIRENMKYQDVPLVANGDCFTLND 233
E D IT H R++ R + N D ++E K VPL GD + D
Sbjct: 352 VEHMKKHSWHTPDLITFHPRSKEQRYTRLANWDFTFPVQEATK--PVPLWVCGDILSWED 409
Query: 234 CYRISEYTKVDGVMAVRGLLCNPALFDGYDK 264
Y E V+G+M RG L P +F D+
Sbjct: 410 YYERLEQYPVNGIMIGRGALIKPWIFTEIDE 440
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.324 0.141 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,454,819
Number of Sequences: 60738
Number of extensions: 909692
Number of successful extensions: 1907
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1850
Number of HSP's gapped (non-prelim): 24
length of query: 351
length of database: 30,389,216
effective HSP length: 107
effective length of query: 244
effective length of database: 23,890,250
effective search space: 5829221000
effective search space used: 5829221000
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)