ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0756 check: MH O KOG0978 Posttranslational modification, protein turnover, chaperones E3 ubiquitin ligase involved in syntaxin degradation
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0756 269789 267801 -663
(663 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL074c [O] KOG0978 E3 ubiquitin ligase involved in syntaxin deg... 500 e-141
SPCC970.10c [O] KOG0978 E3 ubiquitin ligase involved in syntaxin... 127 7e-29
SPCC1919.15 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin... 104 5e-22
7295428 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin deg... 99 2e-20
Hs7662230 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin d... 95 4e-19
Hs16554453 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin ... 89 2e-17
ECU09g0100 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin ... 80 1e-14
At2g44950 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin d... 74 7e-13
At1g55250 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin d... 74 7e-13
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 70 8e-12
CE00283 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin deg... 69 2e-11
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 60 8e-09
SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115 60 1e-08
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 60 1e-08
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 60 1e-08
Hs4557773 [Z] KOG0161 Myosin class II heavy chain 60 1e-08
Hs20542063 [Z] KOG0161 Myosin class II heavy chain 57 7e-08
Hs13124879 [Z] KOG0161 Myosin class II heavy chain 57 7e-08
Hs13124875 [Z] KOG0161 Myosin class II heavy chain 57 7e-08
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 57 7e-08
7303132 [BD] KOG0933 Structural maintenance of chromosome protei... 57 9e-08
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 57 1e-07
7292701_2 [S] KOG4415 Uncharacterized conserved protein 57 1e-07
Hs15313972 [Z] KOG0161 Myosin class II heavy chain 56 2e-07
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 55 3e-07
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 55 3e-07
YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC... 55 4e-07
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 55 4e-07
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 55 4e-07
Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein 54 6e-07
Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and relat... 54 8e-07
At2g33240 [Z] KOG0160 Myosin class V heavy chain 54 8e-07
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 54 8e-07
YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein 54 1e-06
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 54 1e-06
CE03665 [Z] KOG0161 Myosin class II heavy chain 53 1e-06
At1g03830 [R] KOG2037 Guanylate-binding protein 53 1e-06
Hs20558376 [Z] KOG0161 Myosin class II heavy chain 52 3e-06
7303173 [DY] KOG0977 Nuclear envelope protein lamin intermediate... 52 3e-06
SPBC3D6.04c [D] KOG4593 Mitotic checkpoint protein MAD1 52 4e-06
Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 52 4e-06
Hs9055284 [Z] KOG0160 Myosin class V heavy chain 51 5e-06
7291892 [Z] KOG0161 Myosin class II heavy chain 51 5e-06
Hs4826748 [UR] KOG4677 Golgi integral membrane protein 51 6e-06
CE12204 [Z] KOG0161 Myosin class II heavy chain 51 6e-06
YFR031c [BD] KOG0933 Structural maintenance of chromosome protei... 50 8e-06
Hs13376757 [R] KOG1729 FYVE finger containing protein 50 8e-06
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 50 8e-06
>YDL074c [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 700
Score = 500 bits (1288), Expect = e-141
Identities = 288/698 (41%), Positives = 406/698 (57%), Gaps = 46/698 (6%)
Query: 7 KRPKLELSDPSEPLTQKDVIAFQKEALFRCLNKWRVKANQLVEENEVLAAGLSKTTESVS 66
K+ KLELSDPSEPLTQ DVIAFQKEALFRC+N+ RV L ++ E+ + ++
Sbjct: 8 KKIKLELSDPSEPLTQSDVIAFQKEALFRCINRRRVDFEALRKQYELSRRECIDVSRKLA 67
Query: 67 GCCSSIVVLARSVVEDCSDEQDKRFLQQLINTEDEHTLTQIISNNSARICELILK----- 121
+ IV LAR + C+D +K+ +++ ++ +I S +L+ K
Sbjct: 68 NIMALIVTLARFIETFCTDANEKQLCREIAQGDET-----LIVQRSDSFMKLLTKYGKPN 122
Query: 122 ----TSGSNISDNIGRXXXXXXXXXXXXXXX----XXXXXXXXXATEYYENIIAQYDRQD 173
+ SN SD+I EYY NII +YDR +
Sbjct: 123 TTDSNTNSNASDHIQELTTELKNLRKSKEELFYENSQLTEEISALKEYYTNIIRKYDRDE 182
Query: 174 SESVSRVFNTADDDS--------------NVKK-EKQSSTGAXXXXXXXXXXXXXXXXXX 218
S ++ RVF D+ N+K K SS
Sbjct: 183 SFTIKRVFKEDKTDAVKELREDEKESNENNIKSGNKDSSAINGDNTSKKSEKGDELVQAE 242
Query: 219 XXAVSQAHHE-----IEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXX 273
A +E ++ +DL +I+ L +T+K+L + +NE EL + R V
Sbjct: 243 DERKEDAENEKLELDLKFSDLRAEINSLSSTIKDLENIRRENEEELIKTRSEVSNLKKQQ 302
Query: 274 XXXXXXXXXXXXPDASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSE 333
D KI LT+QN +L +IN +L+KFQ L+ ++EI+ K+ E
Sbjct: 303 IAAADQDPDFKSYDHESLLAKIQHLTEQNAELSEINSSFLSKFQVLAKEKEIYTKKVREE 362
Query: 334 FNLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQL 393
F + ++L + N+SLEKD+VRIRT RD+LL+K+++LEA+K+K+E+L DL+ +++I +EQ
Sbjct: 363 FQKSLDSLVEMNSSLEKDVVRIRTARDDLLSKIAILEAEKSKTEVLSDLQHAIDILKEQW 422
Query: 394 QKFESRSSENAS---QDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTK 450
K + RS++ S QDAL+KE+QDLEK FRE+S L++KKY+ +N ESV+SKLTVEKTK
Sbjct: 423 TKIDQRSNDTKSSSTQDALIKEIQDLEKGFRELSDLTHKKYSEIINHESVISKLTVEKTK 482
Query: 451 ASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQEN 510
A +KYFAAMRSKD+I+I I+QLKD ++ LQQKI N+H QL LSQ N
Sbjct: 483 ADQKYFAAMRSKDSILIEIKTLSKSLSKSNELILQLKDSDRLLQQKIGNLHKQLDLSQNN 542
Query: 511 EKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQL 570
E+R+ +S+K ++KI++L + + KLK+S E+L+ E+ I T LE+K+ D +IE K
Sbjct: 543 ERRLIDSSKTETLKIIDLNNTSTKLKRSLEKLQEESNKSIADMTHLETKLNDTEIELKHF 602
Query: 571 KIKVSSAEAKSKKLYKTLL-----SNGGDNGALAEELENFRTIIYCSLCSKNWKNTALKT 625
K K S E+K +KL+ TL + G + AL EEL NFRT++YCSLCSKNWKN A+KT
Sbjct: 603 KQKASHLESKCEKLHDTLFRGNNKNKGSSDEALVEELANFRTLVYCSLCSKNWKNMAIKT 662
Query: 626 CGHVFCDVCCKERLAARMRKCPTCNKPFSSNDLLSIHL 663
CGHVFC+ CCKERLAARMRKCPTCNK FSSNDLL++HL
Sbjct: 663 CGHVFCENCCKERLAARMRKCPTCNKAFSSNDLLTVHL 700
>SPCC970.10c [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 680
Score = 127 bits (318), Expect = 7e-29
Identities = 102/392 (26%), Positives = 180/392 (45%), Gaps = 30/392 (7%)
Query: 293 EKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKDL 352
E +S ++Q L+ + + LS + FN S + L + ++ D
Sbjct: 298 EAVSMTSEQLRVLEHLLSECSHEINVLSQQSKNFNGVFESSYQPLINDLDHQISVMQNDE 357
Query: 353 VRIRTIRDEL-LAKVSLLEAQKTKSEMLED-LEKSLNIQQEQLQKFESRSSENASQDA-- 408
RI + EL L+ LEA+K K ++ +D L++ N++ L+K ++ ++ A+
Sbjct: 358 KRINNAKTELSLSLEKKLEAKKQKEKVYKDKLDELANLETMVLEKKKAVATREAANKIRL 417
Query: 409 ---------------LMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASE 453
L KEL EKAFR V + K +++ + + +++K +VEK KA +
Sbjct: 418 VDLNDLELQKDLSTYLSKELASTEKAFRLVKQQTVK--SSHSHYQELITKFSVEKEKAEQ 475
Query: 454 KYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLS-LSQENEK 512
KYF M+S D++ I ++ + + T +I+ QL+ LS
Sbjct: 476 KYFLTMKSTDSLHAEVKLLRQKYQKTNEIISKMLNSQDTAVHRIIEFEDQLARLSSVRNN 535
Query: 513 RVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKI 572
+K+S K + ++ N L++ L+ T T+LE + D L
Sbjct: 536 SIKQSTTFQVKKSSQKSTIQN-LEEKVSYLQQFMDKNNATLTDLEFQCSDLSSSIDILSK 594
Query: 573 KVSSAEAKSKKLYKTLLSNGGDNGALAEELENFRTIIYCSLCS-KNWKNTALKTCGHVFC 631
+ E + +KL T +S AEEL+ FR + CS+C+ + WK+ + CGH FC
Sbjct: 595 QDEEHEKEKRKLKDTGVSTS------AEELKTFRAMCKCSVCNFERWKDRIISLCGHGFC 648
Query: 632 DVCCKERLAARMRKCPTCNKPFSSNDLLSIHL 663
C ++R+ R R+CP C + F ++D++ IHL
Sbjct: 649 YQCIQKRIETRQRRCPICGRGFGASDVIPIHL 680
>SPCC1919.15 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 692
Score = 104 bits (259), Expect = 5e-22
Identities = 97/410 (23%), Positives = 183/410 (43%), Gaps = 53/410 (12%)
Query: 289 SVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASL 348
S EKI S+ + L + + +++ Q+ ++I + KL Q+ +K +L
Sbjct: 301 SSNEEKIESINRDLSSLFEDIQFFIS--QRTKRQKDIIDLKLAC-VKEKQQLIK----TL 353
Query: 349 EKDLVRIRTIRDELLAK-------------------------VSLLEAQKTKSEMLEDLE 383
E L +IR RD L+AK V++LE + + + +E
Sbjct: 354 ESSLTQIRNERDSLVAKQQMQYTNNLFFDDMMLLLSNLSNARVAILEGYSNRLCIWDRIE 413
Query: 384 KSLNIQQEQLQKFESRSSENASQDALMK-------ELQDLEKAFREVSHLSNKKYAAYLN 436
+S + + + S +++ + L+K EL + AF + KKY
Sbjct: 414 RSKTGEMNNVLDEKEEISASSALEKLIKNNSCLEAELPSMYAAFDQSQSRLLKKYEELET 473
Query: 437 QESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQK 496
+E ++ EK +A++KYFAAM+++D +M I +L++ E L +
Sbjct: 474 KEKKALEMHYEKARATQKYFAAMKARDILMTEKKTLKLAENKEHDYIGKLQEREHALTKY 533
Query: 497 IVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTEL 556
++ +L E K++KE + S VE+ +E+ L+ +L + +LI + +
Sbjct: 534 ESSLKAEL----EVYKQIKEIYGKHS---VEVLTEDKHLQVKQTKLTQKLEDLIESVQKS 586
Query: 557 ESK--IKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELENFRTIIYCSLC 614
K I + + + Q + + S +A K L++ + +E + ++ ++ CS+C
Sbjct: 587 GEKLMIMHQKLFHLQEEHTILSIKASYNKKESHLINQAYET----QEAQVYKGMLKCSVC 642
Query: 615 S-KNWKNTALKTCGHVFCDVCCKERLAARMRKCPTCNKPFSSNDLLSIHL 663
+ NWK+ + CGH FC C + + CP C PFS +D+L+IHL
Sbjct: 643 NFSNWKSKLIPNCGHAFCSNCMEPFYEHKTSTCPQCETPFSVSDILTIHL 692
>7295428 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 1031
Score = 99.0 bits (245), Expect = 2e-20
Identities = 75/345 (21%), Positives = 150/345 (42%), Gaps = 25/345 (7%)
Query: 329 KLTSEFNLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNI 388
KL SE ++ LKK S ++ R + +E L K+ LE QK +L+K +
Sbjct: 701 KLRSEIEELRQQLKKLQESKREE--RKKLADEEALRKIKQLEEQKY------ELQKQMAN 752
Query: 389 QQEQLQKFESRSSENAS----------QDALMKELQDLEKAFREVSHLSNKKYAAYLNQE 438
+ + S + A+ ++AL+ E++ +AF ++ +++ ++
Sbjct: 753 HKPTDNSWGSGAPGTANYTRPFVGSHEEEALLNEMEVTGQAFEDMQEQNSRLIQQLREKD 812
Query: 439 SVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIV 498
KL E+ KA++ + K + + +L++ E++LQ +
Sbjct: 813 DANFKLMSERIKANQLHKLLREEKTVLEDQMATATTQIEAMHIVLRKLEEKERSLQATVA 872
Query: 499 NVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELES 558
++ +L L Q+ + K K +E LK E+ ++ + E S
Sbjct: 873 SIEKELMLRQQAMEMHKR-------KAIESAQSAADLKLHLEKYHAQMKEAQQVVAEKTS 925
Query: 559 KIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELENFRTIIYCSLCSKNW 618
++ + + K+L+ +++ + K++++ K +S + + EE+ ++ + C C
Sbjct: 926 SLEAEAYKTKRLQEELAQFKRKAERMKKMEMSGTTIDEVMIEEIREYKETLTCPSCKVKR 985
Query: 619 KNTALKTCGHVFCDVCCKERLAARMRKCPTCNKPFSSNDLLSIHL 663
K+ L C HVFC C + R R RKCP CN F +ND ++L
Sbjct: 986 KDAVLSKCFHVFCYDCLRTRYETRQRKCPKCNCAFGANDYHRLYL 1030
>Hs7662230 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 1001
Score = 94.7 bits (234), Expect = 4e-19
Identities = 69/308 (22%), Positives = 137/308 (44%), Gaps = 12/308 (3%)
Query: 360 DELLAKVSLLEAQ---KTKSEMLEDLEKSLNIQQEQLQKFESR-SSENASQDALMKELQD 415
DEL +++ LE + ++K ED + + +EQ++ + + + ++AL+ E+
Sbjct: 701 DELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDV 760
Query: 416 LEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXX 475
+AF ++ + + ++ KL E+ KA++ + KD +
Sbjct: 761 TGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQ 820
Query: 476 XXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKL 535
+ +L++ E+ LQ + V +L+L + E NK +++ +L + L
Sbjct: 821 VDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQ----ALELNKRKAVEAAQLAED---L 873
Query: 536 KKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDN 595
K E +++ R + E + + + K+ + +S K +K K + D
Sbjct: 874 KVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADE 933
Query: 596 GALAEELENFRTIIYCSLCSKNWKNTALKTCGHVFCDVCCKERLAARMRKCPTCNKPFSS 655
L EE++ ++ + C C+ K+ L C HVFC C + R AR RKCP CN F +
Sbjct: 934 -ILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGA 992
Query: 656 NDLLSIHL 663
+D I++
Sbjct: 993 HDFHRIYI 1000
>Hs16554453 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 975
Score = 89.0 bits (219), Expect = 2e-17
Identities = 101/455 (22%), Positives = 189/455 (41%), Gaps = 46/455 (10%)
Query: 233 DLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPDASVTN 292
DL++Q S +A+ ++ E K++ + E E + +
Sbjct: 542 DLSSQSSASKASQEDANEIKSKRDEEERERERR-------EKEREREREREKEKEREREK 594
Query: 293 EKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKDL 352
+K+ K+ + + +G ++ A+ +L E AQE+ K+ L+
Sbjct: 595 QKLKESEKERDSAKDKEKGKHDDGRKKEAE---IIKQLKIELKKAQESQKEMKLLLDM-- 649
Query: 353 VRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQDALMKE 412
R+ E KV L+ A+K LEDL + L +++ +K +++ A +DAL K
Sbjct: 650 --YRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKK---ENTKMADEDALRK- 703
Query: 413 LQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTV------EKTKASEKYFAAMRSKD--- 463
+ ++ +L K A +E++LS++ V + + + + +R KD
Sbjct: 704 ---IRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDAN 760
Query: 464 -AIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETS 522
+M +L D TL+ + V+ +Q+ E ++ + +SN T
Sbjct: 761 FKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQ-VDAQLQVVRKLEEKEHLLQSNIGTG 819
Query: 523 MKIVELTSENNKLKKSTERLESETRNLIGTKTELESK----IKDKDIENKQLKIK----- 573
K + L ++ ++ K ++ + + + EL K +D+ +EN K K
Sbjct: 820 EKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNF 879
Query: 574 VSSAEAKSKKLYKTLLSNGGDN-----GALAEELENFRTIIYCSLCSKNWKNTALKTCGH 628
+ E S+ K + DN L EE+++++ + C C+ K+ L C H
Sbjct: 880 KRAQEDISRLRRKLETTKKPDNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFH 939
Query: 629 VFCDVCCKERLAARMRKCPTCNKPFSSNDLLSIHL 663
VFC C K R R RKCP CN F +ND I++
Sbjct: 940 VFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYI 974
>ECU09g0100 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 527
Score = 79.7 bits (195), Expect = 1e-14
Identities = 101/451 (22%), Positives = 193/451 (42%), Gaps = 32/451 (7%)
Query: 233 DLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPDASVTN 292
D+ ++IS L ++ L ++ E+ L+ + D+ VT+
Sbjct: 89 DIGSRISSLNYEIRRLNSVIHEMEKRLARVGMFRESKDMPSDGDSAEKKHSIADDSMVTS 148
Query: 293 EKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSE-----FNLAQETLKKHNAS 347
E + + L+ G +K ++ +++ LT E FN AQE K +A
Sbjct: 149 EVYKKIIDEYGDLRAKMAGLESKHEEELCEKDQKIAGLTRELCEITFN-AQEVSKMFDA- 206
Query: 348 LEKDLVRIRTIRDELLAKVSLLEAQKTKS-EMLEDLEKSLNIQQEQLQKFESRSSENASQ 406
L+ + + R I L K L + + + LE ++K + L + R+ + A +
Sbjct: 207 LKAENEKRREILCGLGEKEMGLRREMDQCLQKLEKVDKDIQSVMSGLDLWMKRAEQLAVE 266
Query: 407 DALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIM 466
+EL + + ++ + N A +E L + + ++ +K ++ A++
Sbjct: 267 K---EELSRIVENYKRCERVRNTS-AGGAYEEGSLEEEIINLVESLDK---SLGENKALI 319
Query: 467 IXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLS-LSQENEKRVKESNKETSMKI 525
++ L+ L K + + L E S+ + S+KI
Sbjct: 320 AKLENMHKKNRELENEMIALRMTNADLGSKNTKLELDAKQLRMEGRGNTCRSSGD-SLKI 378
Query: 526 VELT---SENNKLKKSTER------LESETRNLIGTKTELESKIKDKDIENKQLKIKVSS 576
+L +E++KL ++ +E E I + + +S+ + +D +K K+ S
Sbjct: 379 KKLEDSIAESSKLALDYKKRLHFLFIEKEENEKILERIKRQSR-EARDEVSKLTKVN-SQ 436
Query: 577 AEAKSKKLYKTL--LSNGGDNGA--LAEELENFRTIIYCSLCSKNWKNTALKTCGHVFCD 632
EA++K+L L + NG G LA +LE +R ++ CSLC +K+TA+ C H FC+
Sbjct: 437 IEAENKRLNGILRAIQNGDSEGDPDLAVQLERYRGLLRCSLCDTRFKDTAIIKCMHCFCE 496
Query: 633 VCCKERLAARMRKCPTCNKPFSSNDLLSIHL 663
C R+ R R+CP+CN+ F+ D+ I L
Sbjct: 497 ECVNSRIRMRDRRCPSCNESFAPCDVRKIFL 527
>At2g44950 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 518
Score = 73.9 bits (180), Expect = 7e-13
Identities = 68/379 (17%), Positives = 159/379 (41%), Gaps = 27/379 (7%)
Query: 292 NEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKD 351
N + L +E+L+ +L +++ S D E+ A ++ +SL++
Sbjct: 160 NATVCDLKNSHEELKL----FLDMYKRESTDARDIAEAKEQEYR-AWAHVQSLKSSLDEQ 214
Query: 352 LVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQDALMK 411
+ +R VS ++E+ + +K + +++ + + S++ +
Sbjct: 215 NLELRVKAANEAEAVSQQMLAAAEAEIADLRQKMDDCKRDVAKHSDILKSKHEEHGTYLS 274
Query: 412 ELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXX 471
E+Q + A+ ++ + + ++ KL +E + + +D ++I
Sbjct: 275 EIQTIGSAYEDIVPQNQQLLLQVTERDDYNIKLFLEG-------ITSRQMQDTLLIDKYI 327
Query: 472 XXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSE 531
I Q L +K + QL + +++ E + S+ + L +
Sbjct: 328 MDKD-------IQQGSAYASFLSKKSSRIEDQLRFCTDQFQKLAEDKYQKSVSLENLQKK 380
Query: 532 N----NKLKKSTERLESETRNLIGTKTE---LESKIKDKDIENKQLKIKVSSAEAKSKKL 584
N L+++ RLE + ++ + LE +++ + ++++ ++ A+ K +L
Sbjct: 381 RADIGNGLEQARSRLEESHSKVEQSRLDYGALELELEIERFNRRRIEEEMEIAKKKVSRL 440
Query: 585 YKTLLSNGGDNGALAEELENFRTIIYCSLCSKNWKNTALKTCGHVFCDVCCKERLAARMR 644
++L+ L +EL F+ I+ C C+ K + C H+FC+ C ++ R +
Sbjct: 441 -RSLIEGSSAIQKLRQELSEFKEILKCKACNDRPKEVVITKCYHLFCNPCVQKLTGTRQK 499
Query: 645 KCPTCNKPFSSNDLLSIHL 663
KCPTC+ F ND+ I++
Sbjct: 500 KCPTCSASFGPNDIKPIYI 518
>At1g55250 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 899
Score = 73.9 bits (180), Expect = 7e-13
Identities = 75/381 (19%), Positives = 152/381 (39%), Gaps = 31/381 (8%)
Query: 293 EKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKDL 352
+K + + + L+ + E L + QL I + + LA+ +K +
Sbjct: 530 DKCAKQMAEIKSLKALIEKLLKEKLQLQNLASICTRECNDDRGLAE--IKDSQRKAQAQA 587
Query: 353 VRIRTIRDELLAKVSLLEAQKTKSEMLE----------DLEKSLNI-QQEQLQKFESRSS 401
++ + DE ++ + A +T+S E +L L++ ++E L+ E
Sbjct: 588 EELKNVLDEHFLELRVKAAHETESACQERLATAKAEIAELRTQLDLSEREVLELKEGIKV 647
Query: 402 ENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRS 461
+ +A + E++ + +A+ ++ + ++ KL E K Y +
Sbjct: 648 KEQEAEASIAEMETIGQAYEDMQTQNQHLLQQVAERDDYNIKLVSESVKTKHAYNTHLSE 707
Query: 462 KDAIMIXXXXXXXXXXXXXXXIVQLKDLEK---TLQQKIVNVHMQLSLSQENEK-RVKES 517
K + I ++ K + K++ L +S E K V ++
Sbjct: 708 KQVMEKQLHQVNASVENFKARIAHNEEQMKGCFSEAYKLIQEDRHLVISLETTKWEVADA 767
Query: 518 NKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSA 577
+KE L S + +K E++ T ++ K EL+ + + K +E + +++
Sbjct: 768 DKEFRW----LKSAVSSSEKEYEQISRRTDDI---KLELDDEREKKKLEEELMELNKELE 820
Query: 578 EAKSKKLYKTLLSNGGDNGALAEELENFRTIIYCSLCSKNWKNTALKTCGHVFCDVCCKE 637
E S+ + ++ L EE++N + I+ C +C K + C H+FC C +
Sbjct: 821 ELGSESVEAAIVR-------LQEEVKNCKNILKCGVCFDRPKEVVIVKCYHLFCQQCIQR 873
Query: 638 RLAARMRKCPTCNKPFSSNDL 658
L R RKCP C F ND+
Sbjct: 874 SLEIRHRKCPGCGTAFGQNDV 894
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 70.5 bits (171), Expect = 8e-12
Identities = 97/464 (20%), Positives = 191/464 (40%), Gaps = 68/464 (14%)
Query: 162 YENIIAQYDRQDSESVSR----VFNTADDDSNVKKEKQSSTGAXXXXXXXXXXXXXXXXX 217
YE IA +RQ +E +S+ + +T ++ ++KK+ G
Sbjct: 1164 YEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKS 1223
Query: 218 XXXAVSQAHHEIEINDLNTQISVLEAT---------VKELTEWKNQNERELSELRQTVXX 268
A++ E++ + + S+LE+ +KEL + N E+E+SEL +
Sbjct: 1224 EIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKA 1283
Query: 269 XXXXXXXXXXXXXXXXXP----DASVTN-----EKISSLTKQNEQLQQINEGYLTKFQQL 319
DA T EKI++L+K E+ +E L++ ++
Sbjct: 1284 SEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEK----SESELSRLKKT 1339
Query: 320 SADR----EIFNNKLTSEFNLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTK 375
S++ E KL +E + + +K L + TI E K++ LE + +
Sbjct: 1340 SSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGS---STITQEYSEKINTLEDELIR 1396
Query: 376 SEMLEDLE-KSLNIQQEQLQKFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAY 434
+ +L+ K ++ + +L+K + S D L++E Q+ K+ ++ + + K
Sbjct: 1397 LQNENELKAKEIDNTRSELEKV------SLSNDELLEEKQNTIKSLQD--EILSYKDKIT 1448
Query: 435 LNQESVLS-----KLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDL 489
N E +LS K +E K E+ AA SK + LK L
Sbjct: 1449 RNDEKLLSIERDNKRDLESLK--EQLRAAQESKAKVEEG-----------------LKKL 1489
Query: 490 EKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNL 549
E+ ++ + + ++ E ++ + E + + + KL++S + E + +NL
Sbjct: 1490 EEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNL 1549
Query: 550 IGTKTELESKI--KDKDIENKQLKIKVSSAEAKSKKLYKTLLSN 591
K++L S+I +KDIE + K+++ + + K L+N
Sbjct: 1550 QHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNN 1593
Score = 62.8 bits (151), Expect = 2e-09
Identities = 63/302 (20%), Positives = 127/302 (41%), Gaps = 23/302 (7%)
Query: 294 KISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLT---SEFNLAQETLKKHNASLEK 350
KI+ + NE L+++ + LS ++E + +L S F + K L+
Sbjct: 911 KITEIKAINENLEEMK----IQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKS 966
Query: 351 DLVRIRTIRDELLAKVSLLEAQKTKSEM-LEDLEKSLNIQQEQLQKFE-SRSSENASQDA 408
+ ++ E + + +E K +S + L +L+ ++ ++ + F+ R S + +
Sbjct: 967 LANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQ 1026
Query: 409 LMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIX 468
L K + DLE+ E+ S+ Y +Q S+L EK A + D +
Sbjct: 1027 LKKTISDLEQTKEEIISKSDSSKDEYESQISLLK----------EKLETATTANDENVNK 1076
Query: 469 XXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVEL 528
+ K+L+ L+ K+ L +ENE+ +KE + + E
Sbjct: 1077 ISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATET 1136
Query: 529 TSENNKLKKSTERLESETRNLIGTKTELESKIKDKD----IENKQLKIKVSSAEAKSKKL 584
+ N L+ + E LE E +L + E +I +K+ E QL +++S + +++ +
Sbjct: 1137 KQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESI 1196
Query: 585 YK 586
K
Sbjct: 1197 KK 1198
Score = 57.4 bits (137), Expect = 7e-08
Identities = 67/357 (18%), Positives = 141/357 (38%), Gaps = 22/357 (6%)
Query: 223 SQAHHEIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXX 282
S +H+ E L I+ +K + E + + + + L +
Sbjct: 893 SNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQS 952
Query: 283 XXXPDASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREI----FNNKLTSEFNLAQ 338
A +T EK+ SL + +Q NE + ++ + I NK+ S + +
Sbjct: 953 HDNLVAKLT-EKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDS-MSQEK 1010
Query: 339 ETLKKHNASLEKDLVRIR-TIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFE 397
E + S+EK++ +++ TI D K ++ + + + E +++ +E+L+
Sbjct: 1011 ENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKD---EYESQISLLKEKLETAT 1067
Query: 398 SRSSENASQ-DALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYF 456
+ + EN ++ L K ++LE +L N+ L + S+ +++ K +E++
Sbjct: 1068 TANDENVNKISELTKTREELEAELAAYKNLKNE-----LETKLETSEKALKEVKENEEHL 1122
Query: 457 AAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKE 516
K+ + L+ LEK + + E++ E
Sbjct: 1123 -----KEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNE 1177
Query: 517 SNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIK 573
+ + +I EN +KK + LE E + + T E +S +K +I+ L+IK
Sbjct: 1178 EISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEE-QSNLKKSEIDALNLQIK 1233
Score = 52.8 bits (125), Expect = 2e-06
Identities = 72/330 (21%), Positives = 135/330 (40%), Gaps = 49/330 (14%)
Query: 296 SSLTKQNEQLQQINEGYLTKFQQLSADREIFNNK------LTSEFNLAQETLKKHNASLE 349
S++ KQ + ++ + +G T Q + N L+ E +E K N E
Sbjct: 832 STIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCK--NLQKE 889
Query: 350 KDLVRI------RTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQK-FESRSSE 402
KD + +++++++ AK++ ++A E ++ +L+ ++E + K S
Sbjct: 890 KDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSR 949
Query: 403 NASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSK 462
S D L+ +L + K+ L+N ES++ + K ++S +
Sbjct: 950 FQSHDNLVAKLTEKLKS------LANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKI 1003
Query: 463 DAIMIXXXXXXXXXXXXXXXIVQLK----DLEKTLQQKIVN-------VHMQLSLSQENE 511
D++ I QLK DLE+T ++ I Q+SL +E
Sbjct: 1004 DSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKL 1063
Query: 512 KRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESK----------IK 561
+ +N E KI ELT K+ E LE+E K ELE+K +K
Sbjct: 1064 ETATTANDENVNKISELT-------KTREELEAELAAYKNLKNELETKLETSEKALKEVK 1116
Query: 562 DKDIENKQLKIKVSSAEAKSKKLYKTLLSN 591
+ + K+ KI++ ++K+ +L +N
Sbjct: 1117 ENEEHLKEEKIQLEKEATETKQQLNSLRAN 1146
>CE00283 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 834
Score = 68.9 bits (167), Expect = 2e-11
Identities = 80/377 (21%), Positives = 140/377 (36%), Gaps = 47/377 (12%)
Query: 333 EFNLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLED------LEKSL 386
E TL+ N SL+ + +R+R + ++ L+++ T + +D LE
Sbjct: 459 EMKATLNTLRSMNRSLKSEKIRLREKDKQSQKDINTLKSELTSLKEAQDKCLLVPLEDVS 518
Query: 387 NIQQEQL----QKFESRSSENASQDALMKE-----------------LQDLEKAFREVSH 425
N E + Q++ES E A+ K+ L +LE +
Sbjct: 519 NAPPEDVNKIRQEYESLCKEVKRLGAMEKQEKQKQVEKEVNRQIADKLSELETLRKTNEM 578
Query: 426 LSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQ 485
L+N + E++ + + E+ + ++ Y +D + +
Sbjct: 579 LTNDEECISDELEAIGTAVEEEQERNAQLYIEKREQEDRNLKMMNDRMIQNQTFNRLREK 638
Query: 486 LKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLE-- 543
L LE Q M + NE+ V + ++ K ELT N +++ + ++
Sbjct: 639 LSCLESKAQTDAQIAKMHEFEKKANEELVTKLSESVQFKSAELTRLTNLMEQHRKNIQEV 698
Query: 544 --SETRNLI------GTKTELESKIKDKDIENKQLKIKVSSAEAKSKKL---YKTLLSN- 591
S N I G +++ K E + K K AE + + L Y+ + N
Sbjct: 699 GMSRDENQIKADRCEGQMKQIQELYAAKAREIEDFKFKRQRAEEELETLRIKYERVKRNE 758
Query: 592 -----GGDNGALAEELENFRTIIYCSLCSKNWKNTALKTCGHVFCDVCCKERLAARMRKC 646
GD L E + + C C K+ + C H+FC+ C K R RKC
Sbjct: 759 SVPAQSGDQ-VLEEANRQMKETLTCPSCKTRPKDCIMLKCYHLFCETCIKTMYDTRQRKC 817
Query: 647 PTCNKPFSSNDLLSIHL 663
P CN F +ND I +
Sbjct: 818 PKCNSNFGANDFHRIFI 834
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 60.5 bits (145), Expect = 8e-09
Identities = 77/376 (20%), Positives = 150/376 (39%), Gaps = 63/376 (16%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXX---- 283
E E ++L I LE T+ ++ + K+ E ++ L + +
Sbjct: 948 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAH 1007
Query: 284 --XXPDASVTNEKISSLTKQNEQL-QQIN--EGYLTKFQQLSADREIFNNKLTSEFNLAQ 338
D + +K+++LTK +L QQ++ EG L + ++L D E KL + LAQ
Sbjct: 1008 QQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQ 1067
Query: 339 ETL-------KKHNASLEKDLVRIRT----IRDELLAKVSLLEAQKTKSEMLEDLEKSLN 387
E+ ++ N L+K + I DE + L + K +E+LE+ +
Sbjct: 1068 ESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIE 1127
Query: 388 IQQEQLQKFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKL--- 444
++ K E + S+ L +EL+++ + E ++ + +E+ K+
Sbjct: 1128 AERASRAKAEKQRSD------LSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRD 1181
Query: 445 TVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQL 504
E T E AA+R K A + + Q+
Sbjct: 1182 LEESTLQHEATAAALRKKHA------------------------------DSVAELGKQI 1211
Query: 505 SLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKD 564
Q ++++++ E M+I +L S + K+ E R L + S+IK K+
Sbjct: 1212 DSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTL----EDQLSEIKTKE 1267
Query: 565 IENKQLKIKVSSAEAK 580
E ++L ++S+ +A+
Sbjct: 1268 EEQQRLINELSAQKAR 1283
>SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1044
Score = 60.1 bits (144), Expect = 1e-08
Identities = 81/331 (24%), Positives = 139/331 (41%), Gaps = 34/331 (10%)
Query: 293 EKISSLTKQNEQLQQI-------NEGYLTKFQQLS------ADREIFNNKLTSEFNLAQE 339
E+ S LTKQ + ++ N L++ ++ A E N KL ++ NL E
Sbjct: 705 EEHSKLTKQLDDIKNQFGIISSKNRDLLSELEKSKSLNNSLAALESKNKKLENDLNLLTE 764
Query: 340 TLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESR 399
L K NA E TIR+ L+K +L + K ++ DL+ L+ + +LQ+ +S+
Sbjct: 765 KLNKKNADTESFK---NTIREAELSKKALNDNLGNKENIISDLKNKLSEESTRLQELQSQ 821
Query: 400 SSENASQDALMKELQDLEKAFREVSHLS--NKKYAAYLNQESVLSKLTVEKTKASEKYFA 457
+++ +Q + E + A E+S + NK A L EK K
Sbjct: 822 LNQDKNQIETLNER--ISAAADELSSMESINKNQANELKLAKQKCSNLQEKINFGNKL-- 877
Query: 458 AMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKES 517
A + I +LK + K N ++ S+S +++ + K
Sbjct: 878 AKEHTEKISSLEKDLEAATKTASTLSKELKTV------KSENDSLK-SVSNDDQNKEKSV 930
Query: 518 NKETSMKIVELTSE-NNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSS 576
N E ++ + +E N KL E +E ++IG + + KD +N+ +S
Sbjct: 931 NNEKFKEVSQALAEANEKLNARDEEIERLKVDIIGLQNASLNMQSLKDSDNR----TISD 986
Query: 577 AEAKSKKLYKTLLSNGGDNGALAEELENFRT 607
E+K+K+L K L + EELE+ RT
Sbjct: 987 LESKNKELEKKLKEADEYWLLIVEELESKRT 1017
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 60.1 bits (144), Expect = 1e-08
Identities = 73/383 (19%), Positives = 157/383 (40%), Gaps = 35/383 (9%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E + NDL++ +S + T L+ ++ ++ L V
Sbjct: 730 EAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSY 789
Query: 288 ASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNAS 347
S++N L + +Q N L +L D E + + + Q+ + KH +
Sbjct: 790 QSISN-LYHELRDDHVNMQSQNNTLLESESKLKTDCENLTQQNMTLIDNVQKLMHKH-VN 847
Query: 348 LEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQD 407
E + ++ + +L + L + + + + D ++ L E + ++S E+A +
Sbjct: 848 QESKVSELKEVNGKL--SLDLKNLRSSLNVAISDNDQILTQLAELSKNYDSLEQESAQLN 905
Query: 408 ALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASE--KYFAAMRSKDAI 465
+ +K L+ A +++ H N++ ++ + + KL +E++K+S+ K A + +
Sbjct: 906 SGLKSLE----AEKQLLHTENEEL--HIRLDKLTGKLKIEESKSSDLGKKLTARQEE--- 956
Query: 466 MIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKI 525
I LK+ + Q I +V +L + +++ + K+
Sbjct: 957 -----------------ISNLKEENMSQSQAITSVKSKLDETLSKSSKLEADIEHLKNKV 999
Query: 526 VELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLY 585
E+ E N L S ERL + +N L+++I+ K EN L+ K+S ++ + L
Sbjct: 1000 SEVEVERNALLASNERLMDDLKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSEYENL- 1058
Query: 586 KTLLSNGGDNGALAEELENFRTI 608
LL + N +L ++ + I
Sbjct: 1059 --LLISSQTNKSLEDKTNQLKYI 1079
Score = 55.5 bits (132), Expect = 3e-07
Identities = 89/449 (19%), Positives = 177/449 (38%), Gaps = 71/449 (15%)
Query: 226 HHEIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXX------ 279
H + I DL+T+IS + E +NE+ LR T+
Sbjct: 316 HKDKLIEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVE 375
Query: 280 ---XXXXXXPDASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNL 336
+ K+SS ++N+ L+ G + ++Q + ++ +++S+
Sbjct: 376 LKESNRTIHSQLTDAESKLSSFEQENKSLK----GSIDEYQNNLSSKDKMVKQVSSQLEE 431
Query: 337 AQETLKKHNASL----------EKDLVRIRTIRDELLAKVSLLEAQ-KTKSEMLEDLEKS 385
A+ +L L K + I +L A ++ + K KS +++ ++
Sbjct: 432 ARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALIDKKDQE 491
Query: 386 LNIQQEQL--QKFESRSSENASQDA---LMKELQDLEKAFREVSHLSNKKYAAYLNQE-- 438
LN +EQ+ QK S S++++ Q ++ E + E +++ L + N E
Sbjct: 492 LNNLREQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEISNSEHL 551
Query: 439 -SVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQ--- 494
S LS L EK A SK+++ ++QLK+ E+
Sbjct: 552 SSQLSTLAAEKEAAVATNNELSESKNSLQ---TLCNAFQEKLAKSVMQLKENEQNFSSLD 608
Query: 495 ---QKIVNVHMQLSLSQENEKRVKESNKETSMKIVEL--------------TSENNKLKK 537
+K+ H +L + N + + + K+TS K+ +L + ENN L+
Sbjct: 609 TSFKKLNESHQEL---ENNHQTITKQLKDTSSKLQQLQLERANFEQKESTLSDENNDLRT 665
Query: 538 STERLESETRNLIGTKTELESKIKD-----KDIENKQLKIKVSSAEAKS--------KKL 584
+LE ++LI + +++S K+ +D+ + ++ S EAK+ K
Sbjct: 666 KLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALRFSKLEAKNLREVIDNLKGK 725
Query: 585 YKTLLSNGGDNGALAEELENFRTIIYCSL 613
++TL + D + + +N I+ L
Sbjct: 726 HETLEAQRNDLHSSLSDAKNTNAILSSEL 754
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 59.7 bits (143), Expect = 1e-08
Identities = 95/437 (21%), Positives = 183/437 (41%), Gaps = 41/437 (9%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E +I ++ + E ELT K + E E SEL++ +
Sbjct: 922 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 981
Query: 288 ASVT------NEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQ--- 338
++T +E I+ LTK+ + LQ+ ++ L L A+ + N ++ L Q
Sbjct: 982 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQAEEDKVNTLTKAKIKLEQQVD 1038
Query: 339 --ETLKKHNASLEKDLVRI-RTIRDEL-LAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQ 394
E + L DL R R + +L LA+ S+++ + K ++ E L+K ++ ++
Sbjct: 1039 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKK----KEFEIS 1094
Query: 395 KFESR-SSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASE 453
+S+ E A L K++++L+ E+ + A+ E S L+ E + SE
Sbjct: 1095 NLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1154
Query: 454 KYFAAMRSKDAIMIXXXXXXXXXXXXXXXI----VQLKDLEKTLQQKIVNVHMQLSLSQE 509
+ A + A + + +Q + TL++K + +L +
Sbjct: 1155 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID 1214
Query: 510 NEKRVKE----SNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDK-- 563
N +RVK+ E M+I +L S + K+ LE R L +EL+SK +++
Sbjct: 1215 NLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQR 1274
Query: 564 ---DIENKQLKIKVSSAE----AKSKKLYKTLLSNGGDNGALAEELENFRTIIYCSLCSK 616
D+ ++ +++ S E K+ + LS G A +++E + + + +K
Sbjct: 1275 LINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRG--KQAFTQQIEELKRQLEEEIKAK 1332
Query: 617 NWKNTALKTCGHVFCDV 633
N AL++ H CD+
Sbjct: 1333 NALAHALQSSRH-DCDL 1348
>Hs4557773 [Z] KOG0161 Myosin class II heavy chain
Length = 1935
Score = 59.7 bits (143), Expect = 1e-08
Identities = 95/442 (21%), Positives = 178/442 (39%), Gaps = 51/442 (11%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E ++ ++N ++ E ELT K + E E SEL++ +
Sbjct: 916 EAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 288 ASVTNEK------ISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETL 341
++T E I+ LTK+ + LQ+ ++ L L A+ + N ++ L Q+
Sbjct: 976 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL---DDLQAEEDKVNTLTKAKVKLEQQV- 1031
Query: 342 KKHNASLEKDLVRIRTIRDEL-LAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQK--FES 398
LE L + + +R +L AK L K E + DLE E+L+K FE
Sbjct: 1032 ----DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFEL 1087
Query: 399 RS------SENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKAS 452
+ E A L K+L++L+ E+ + A E + S L+ E + S
Sbjct: 1088 NALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEIS 1147
Query: 453 EKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEK-TLQQK-------------IV 498
E R ++A +DLE+ TLQ + +
Sbjct: 1148 E------RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVA 1201
Query: 499 NVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELES 558
+ Q+ Q ++++++ E +++ ++TS ++ K+ LE R L E S
Sbjct: 1202 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Query: 559 KIKD-----KDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGAL--AEELENFRTIIYC 611
K ++ D+ +++ K++ + E + K L + G L ++LE+ + +
Sbjct: 1262 KAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEE 1321
Query: 612 SLCSKNWKNTALKTCGHVFCDV 633
+ +KN AL++ H CD+
Sbjct: 1322 EVKAKNALAHALQSARH-DCDL 1342
Score = 55.5 bits (132), Expect = 3e-07
Identities = 69/314 (21%), Positives = 129/314 (40%), Gaps = 54/314 (17%)
Query: 320 SADREIFNNKLTSEFNLAQETLKKHNA---SLEKDLVRIRTIRDELLAKV-----SLLEA 371
SA+RE + EF +E L+K A LE+ +V + +++L +V +L +A
Sbjct: 842 SAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADA 901
Query: 372 QKTKSEMLED---LEKSLNIQQEQLQKFESRSSENASQ--------DALMKELQDLEKAF 420
++ +++++ LE + E+L+ E ++E ++ L +++ DLE
Sbjct: 902 EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTL 961
Query: 421 REVS---HLSNKKYAAYLNQ----ESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXX 473
+V H + K + + +++KLT EK E + A+ D +
Sbjct: 962 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL---DDLQAEEDKVN 1018
Query: 474 XXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENN 533
Q+ DLE +L+Q EK+V+ ++L
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQ---------------EKKVR----------MDLERAKR 1053
Query: 534 KLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGG 593
KL+ + + +L K +L+ ++K KD E L ++ +A +L K L
Sbjct: 1054 KLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQA 1113
Query: 594 DNGALAEELENFRT 607
L EELE+ RT
Sbjct: 1114 RIEELEEELESERT 1127
>Hs20542063 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 57.4 bits (137), Expect = 7e-08
Identities = 71/314 (22%), Positives = 130/314 (40%), Gaps = 54/314 (17%)
Query: 320 SADREIFNNKLTSEFNLAQETLKKHNA---SLEKDLVRIRTIRDELLAKV-----SLLEA 371
SA+ E + EF +ETL+K A LE+ +V + +++L +V +L +A
Sbjct: 844 SAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDA 903
Query: 372 QKTKSEMLED---LEKSLNIQQEQLQKFESRSSENASQ--------DALMKELQDLEKAF 420
++ +++++ LE + E+L+ E ++E ++ L K++ DLE
Sbjct: 904 EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTL 963
Query: 421 REVS---HLSNKKYAAYLNQ----ESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXX 473
+V H + K + + +++KLT EK E + A+ D + +
Sbjct: 964 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL---DDLQVEEDKVN 1020
Query: 474 XXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENN 533
Q+ DLE +L+Q EK+V+ ++L
Sbjct: 1021 SLSKSKVKLEQQVDDLEGSLEQ---------------EKKVR----------MDLERAKR 1055
Query: 534 KLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGG 593
KL+ + + +L K +LE K+K K+ + Q K+ + + +L K L N
Sbjct: 1056 KLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQA 1115
Query: 594 DNGALAEELENFRT 607
L EELE RT
Sbjct: 1116 RIEELEEELEAERT 1129
Score = 53.5 bits (127), Expect = 1e-06
Identities = 81/401 (20%), Positives = 157/401 (38%), Gaps = 37/401 (9%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E ++ ++N ++ E ELT K + E E SEL++ +
Sbjct: 918 EAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 977
Query: 288 ASVTNEK------ISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETL 341
++T E I+ LTK+ + LQ+ + QQ D ++ +K+ S + ++ L
Sbjct: 978 KNLTEEMAGLDEIIAKLTKEKKALQEAH-------QQALDDLQVEEDKVNS-LSKSKVKL 1029
Query: 342 KKHNASLEKDLVRIRTIRDEL-LAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQK--FES 398
++ LE L + + +R +L AK L K E + DLE +E+L+K F+
Sbjct: 1030 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDI 1089
Query: 399 RSSENASQD------ALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKAS 452
+ +D L K+L++ + E+ + A E + S L+ E + S
Sbjct: 1090 NQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEIS 1149
Query: 453 EKYFAAMRSKDAIMIXXXXXXXXXXXXXXXI----VQLKDLEKTLQQKIVNVHMQLSLSQ 508
E+ A + + + +Q + L++K + +L
Sbjct: 1150 ERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQI 1209
Query: 509 ENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENK 568
+N +RVK+ +L E ++ K + + S +I K LE + + +
Sbjct: 1210 DNLQRVKQ----------KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQAN 1259
Query: 569 QLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELENFRTII 609
+ ++K+ A+ +NG LA +LE +I
Sbjct: 1260 EYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALI 1300
>Hs13124879 [Z] KOG0161 Myosin class II heavy chain
Length = 1972
Score = 57.4 bits (137), Expect = 7e-08
Identities = 71/340 (20%), Positives = 140/340 (40%), Gaps = 50/340 (14%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E I+DL T ++ E K LT+ KN++E +SEL
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL------------------------- 1039
Query: 288 ASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNAS 347
V +K ++ E+L++ EG + F + AD + +L + +E L+ A
Sbjct: 1040 -EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 348 LEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQ- 406
L+ ++ + ++ L K+ LE + DL++ L+ ++ K E + + +
Sbjct: 1099 LDDEIAQ----KNNALKKIRELEGH------ISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Query: 407 DALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIM 466
+AL EL+D + L K+ + +VL K E+T++ E MR K A
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKRE----QEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 467 IXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIV 526
+ L ++TL+++ ++ +L + + ++ V+ K+ ++
Sbjct: 1205 VEELTEQLEQFKRAK--ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 527 ELTSE-------NNKLKKSTERLESETRNLIGTKTELESK 559
EL S+ +L +L++E ++ G E E K
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
>Hs13124875 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 57.4 bits (137), Expect = 7e-08
Identities = 71/340 (20%), Positives = 140/340 (40%), Gaps = 50/340 (14%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E I+DL T ++ E K LT+ KN++E +SEL
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL------------------------- 1039
Query: 288 ASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNAS 347
V +K ++ E+L++ EG + F + AD + +L + +E L+ A
Sbjct: 1040 -EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 348 LEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQ- 406
L+ ++ + ++ L K+ LE + DL++ L+ ++ K E + + +
Sbjct: 1099 LDDEIAQ----KNNALKKIRELEGH------ISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Query: 407 DALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIM 466
+AL EL+D + L K+ + +VL K E+T++ E MR K A
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKRE----QEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 467 IXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIV 526
+ L ++TL+++ ++ +L + + ++ V+ K+ ++
Sbjct: 1205 VEELTEQLEQFKRAK--ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 527 ELTSE-------NNKLKKSTERLESETRNLIGTKTELESK 559
EL S+ +L +L++E ++ G E E K
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 57.4 bits (137), Expect = 7e-08
Identities = 77/394 (19%), Positives = 157/394 (39%), Gaps = 41/394 (10%)
Query: 246 KELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPDASVTNEKISSLTKQNEQL 305
+E+T+ K +N ELS QT AS +KI+ L E +
Sbjct: 1062 EEVTKAKTEN-LELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAI 1120
Query: 306 QQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKDLVRIRTIRDELLAK 365
Q N +LS E+ + + ++ + + + + E+ + ++ I++EL
Sbjct: 1121 QVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKET 1180
Query: 366 VSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQ-DALMKELQD--------- 415
L+ ++ K E LE+ K +++LQ+ S E ++ ++ELQD
Sbjct: 1181 HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELV 1240
Query: 416 --LEKAFREVSHL-------SNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIM 466
LE+ RE S + N+ N+ S L + + ++ +K +
Sbjct: 1241 QNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLS 1300
Query: 467 IXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSL--------------SQENEK 512
+V++++L K L++K+ QL SQENE
Sbjct: 1301 GELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEG 1360
Query: 513 RVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKI 572
++ + + K+ +L N +LK++ + E+ + L G E + ++ + + +++
Sbjct: 1361 NLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQD 1420
Query: 573 KVSSAEAKSKKLYKTLLSNGGDNGALAEELENFR 606
K+ A+ K + L + + LAE+L +
Sbjct: 1421 KLEQAQQKERTLQE-------ETSKLAEQLSQLK 1447
Score = 53.9 bits (128), Expect = 8e-07
Identities = 63/288 (21%), Positives = 123/288 (41%), Gaps = 37/288 (12%)
Query: 330 LTSEFNLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKT----KSEMLEDLEKS 385
L +E + E +++ N L++ ++ + + A +L QK KS +LE EK
Sbjct: 620 LQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKE 679
Query: 386 LNIQQEQLQKFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLT 445
L +EQ K + + Q + +K+L + EK RE++ N L +ES+ +L
Sbjct: 680 LVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTE--NAINQIQLEKESIEQQLA 737
Query: 446 VEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLS 505
+++ + + S+ + LK L++ L+QK + H +L
Sbjct: 738 LKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLG-HEKLQ 796
Query: 506 LSQENEKRVKES-----------------NKETSMKIVELTSENNKLK---------KST 539
+ E K+ KE+ E+++K+V++ E + + K+
Sbjct: 797 AALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTV 856
Query: 540 ERLESETRNLIG----TKTELESKIKDKDIENKQLKIKVSSAEAKSKK 583
+L E L T++EL+S + + ++KQL+ S E ++KK
Sbjct: 857 AKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 904
>7303132 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1179
Score = 57.0 bits (136), Expect = 9e-08
Identities = 72/333 (21%), Positives = 137/333 (40%), Gaps = 48/333 (14%)
Query: 296 SSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTS-EFNLAQETLKKHNASLEKDLVR 354
S + + +Q+ I E F ++ + ++ ++LT E LAQ T +++ A +E+ R
Sbjct: 691 SEIAQVEKQIASI-ENQALAFNKMKENLDLRQHELTMCENRLAQTTFQQNQAEIEEMRER 749
Query: 355 IRTIRDELLAKVSLLEAQKTKSEMLEDLE-----------KSLNIQQEQLQKFESRSSEN 403
++T+ ++ + E QKT + D+E + LN +++ + R+ ++
Sbjct: 750 VKTLEQQI---IDSREKQKTSQAKIVDIEAKLADAKGYRERELNAATNEIKVTKQRAEKS 806
Query: 404 ASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKD 463
+ K Q+ E E++ L A + ++ L EK+ A + D
Sbjct: 807 RAN--WKKREQEFETLQLEITELQKSIETAKKQHQEMIDNL--------EKFKAEL---D 853
Query: 464 AIMIXXXXXXXXXXXXXXXIVQ----LKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNK 519
A+ + I + L+D K ++ ++V L +QE E VK+
Sbjct: 854 ALKVNSSSAASEVTELEQAIKEQKDKLRDQNKEMRNQLVKKEKMLKENQEIELEVKKKEN 913
Query: 520 ETSMKIVELTSENNKLKKSTERLES------ETRNLIGTKTELESKIKDKDIENKQLKIK 573
E +++S+ + KK E LE+ E +N G K K+ E K
Sbjct: 914 EQK----KISSDAKEAKKRMEALEAKYPWIPEEKNCFGMKNTRYDYSKEDPHEAGN---K 966
Query: 574 VSSAEAKSKKLYKTLLSNGGDNGALAEELENFR 606
++ + K K+ +TL N L E ENF+
Sbjct: 967 LAKMQEKKDKMERTLNMNA--IMVLDREEENFK 997
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 56.6 bits (135), Expect = 1e-07
Identities = 81/330 (24%), Positives = 149/330 (44%), Gaps = 32/330 (9%)
Query: 293 EKISSLTKQNEQLQQINEGYLTKFQQLSADRE---IFNNKLTSEFNLAQETLKKHNASLE 349
++IS L N++++ + Y +K ++ D + I+ N T++ N QE L+KH A +
Sbjct: 999 KRISILQNNNKEVEAVKSEYESKLSKIQNDLDQQTIYAN--TAQNNYEQE-LQKH-ADVS 1054
Query: 350 KDLVRIRTIRDELLAKVSLLEAQKTKSE-MLEDLEKSLNIQQE----QLQKFESRSSENA 404
K + +R +V L + + E L++ EKS + Q+E QL SR + +
Sbjct: 1055 KTISELREQLHTYKGQVKTLNLSRDQLENALKENEKSWSSQKESLLEQLDLSNSRIEDLS 1114
Query: 405 SQDALM-KELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRS-- 461
SQ+ L+ ++Q A +EV++ +N ++L L E+ K A R
Sbjct: 1115 SQNKLLYDQIQIYTAADKEVNNSTNGP-----GLNNILITLRRERDILDTKVTVAERDAK 1169
Query: 462 --KDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQK--IVNVHMQLSLSQENEKRVKES 517
+ I + V+ ++ +QQ I+ QL+L +E+ ++
Sbjct: 1170 MLRQKISLMDVELQDARTKLDNSRVEKENHSSIIQQHDDIMEKLNQLNLLRESNITLRNE 1229
Query: 518 NKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSA 577
+ + K EL SE +KLK++ +ESE T L+ +++K+ E K K +V
Sbjct: 1230 LENNNNKKKELQSELDKLKQNVAPIESEL-------TALKYSMQEKEQELKLAKEEVHRW 1282
Query: 578 EAKSKK-LYKTLLSNGGDNGALAEELENFR 606
+ +S+ L K + D L E+EN +
Sbjct: 1283 KKRSQDILEKHEQLSSSDYEKLESEIENLK 1312
Score = 55.1 bits (131), Expect = 3e-07
Identities = 113/498 (22%), Positives = 201/498 (39%), Gaps = 68/498 (13%)
Query: 162 YENIIAQYDRQDSESVSRVFNTADD-DSNVKKEKQSSTGAXXXXXXXXXXXXXXXXXXXX 220
++NII Q +++E + V N AD +S KK KQS
Sbjct: 536 FKNII-QLQEKNAELLKVVRNLADKLESKEKKSKQSLQKIESETVNEAKEAIITLKSEKM 594
Query: 221 AVSQAHHEI--EINDLNTQI-----SVLEATVKELTEWKNQNERELSELRQTVXXXXXXX 273
+ E+ E+ +L T + S T+K+LTE K E ++ +L+ +
Sbjct: 595 DLESRIEELQKELEELKTSVPNEDASYSNVTIKQLTETKRDLESQVQDLQTRISQITRES 654
Query: 274 XXXXX------XXXXXXXPDASVT--NEKIS---------------SLTK-QNEQLQQIN 309
D S+ EK S LTK +N+QL++
Sbjct: 655 TENMSLLNKEIQDLYDSKSDISIKLGKEKSSRILAEERFKLLSNTLDLTKAENDQLRK-R 713
Query: 310 EGYL--TKFQQLSADREIFNNKLTSEFNLA-----------QETLKKH-NASLEKDLVRI 355
YL T +Q S E N ++ + L+ ++ L+ H +L+++L ++
Sbjct: 714 FDYLQNTILKQDSKTHETLNEYVSCKSKLSIVETELLNLKEEQKLRVHLEKNLKQELNKL 773
Query: 356 RTIRDELLAKVSLLEA-QKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQ-DALMKEL 413
+D L V+ L+ QK + ++LE+ KS + ++L+ S + SQ D +K+L
Sbjct: 774 SPEKDSLRIMVTQLQTLQKEREDLLEETRKSCQKKIDELEDALSELKKETSQKDHHIKQL 833
Query: 414 QDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXX 473
++ + + NK A + ESV++ + ++T EK ++S + I
Sbjct: 834 EEDNNS--NIEWYQNKIEALKKDYESVITSVDSKQTDI-EKLQYKVKSLEK-EIEEDKIR 889
Query: 474 XXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENN 533
+ L K L++ +N L+ + K K+ + TS L N+
Sbjct: 890 LHTYNVMDETINDDSLRKELEKSKIN----LTDAYSQIKEYKDLYETTSQ---SLQQTNS 942
Query: 534 KLKKSTERLESETRNLIGTKTELESKI---KDKDIE-NKQLKIKVSSAE---AKSKKLYK 586
KL +S + ++ +NL KT LE KI K++ N +L ++ E A KK
Sbjct: 943 KLDESFKDFTNQIKNLTDEKTSLEDKISLLKEQMFNLNNELDLQKKGMEKEKADFKKRIS 1002
Query: 587 TLLSNGGDNGALAEELEN 604
L +N + A+ E E+
Sbjct: 1003 ILQNNNKEVEAVKSEYES 1020
Score = 54.7 bits (130), Expect = 4e-07
Identities = 80/387 (20%), Positives = 157/387 (39%), Gaps = 43/387 (11%)
Query: 230 EINDLNTQISVLEATVKELTEWKNQNERELSELRQ-TVXXXXXXXXXXXXXXXXXXXPDA 288
E + + ++S+ + V L N + EL+ +R+ +
Sbjct: 288 EKQEFSAEMSLKQRLVDLLESQLNAVKEELNSIRELNTAKVIADDSKKQTPENEDLLKEL 347
Query: 289 SVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASL 348
+T EK++ K+ +L I + + D E + K +S+F ++ L K +
Sbjct: 348 QLTKEKLAQCEKECLRLSSITD-------EADEDNENLSAKSSSDFIFLKKQLIKERRTK 400
Query: 349 EKDLVRIRTIRDELLAKVSLLEAQKTKSEMLED--LEKSLNIQQEQLQKFESRSSENASQ 406
E +I T EL KV ++ + K +++MLE+ +L ++ +K NA
Sbjct: 401 EHLQNQIETFIVELEHKVPIINSFKERTDMLENELNNAALLLEHTSNEKNAKVKELNAKN 460
Query: 407 DALMKELQDLEKAFREVSHLSNK-KYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAI 465
L++ DL+ ++ L + +Y N S SK + K + ++ + +D
Sbjct: 461 QKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSNDSKGPLRKEEI--QFIQNIMQEDDS 518
Query: 466 MIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKI 525
I D +K + +++V + L ++N + +K
Sbjct: 519 TITE-----------------SDSQKVVTERLVEFKNIIQLQEKNAELLKVVRNLAD--- 558
Query: 526 VELTSENNKLKKSTERLESETRN--------LIGTKTELESKIKDKDIENKQLKIKVSSA 577
+L S+ K K+S +++ESET N L K +LES+I++ E ++LK V +
Sbjct: 559 -KLESKEKKSKQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKELEELKTSVPNE 617
Query: 578 EAK-SKKLYKTLLSNGGDNGALAEELE 603
+A S K L D + ++L+
Sbjct: 618 DASYSNVTIKQLTETKRDLESQVQDLQ 644
>7292701_2 [S] KOG4415 Uncharacterized conserved protein
Length = 1643
Score = 56.6 bits (135), Expect = 1e-07
Identities = 72/321 (22%), Positives = 134/321 (41%), Gaps = 27/321 (8%)
Query: 293 EKISSLTKQNEQLQQINEGYLT----KFQQLSADREIFNNKLTSEFNLAQETLKKHNASL 348
E +++K N++ Q+ + T K ++ + ++E+ + E L QE K+ L
Sbjct: 695 EPPKTMSKDNKKKQKPGDAVATMTIDKEKEKAKEKELKLKEKEREAKL-QEKEKEEKLKL 753
Query: 349 EKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQDA 408
++ +R R+E L + + E K + E L++ EK Q+E+ K E + +
Sbjct: 754 KEREESLRMEREEKLKEEKIKE--KEREEKLKE-EKIKEKQREEKLKEEKLKEKEREERM 810
Query: 409 LMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIX 468
KE ++ K + L +K +E + KL EK K EK + ++ M
Sbjct: 811 KEKEREEKAKEKQREEKLREEKIKEKEREEKLKEKLREEKIKEKEKEEKLRKEREEKMRE 870
Query: 469 XXXXXXXXXXXXXXIVQ---------------LKDLEKTLQQKIVNVHMQLSLSQENEKR 513
++ LK+ E+ L++K + +E E++
Sbjct: 871 KEREEKIKEKERVEKIKEKEREEKLKKEKEEKLKEKEELLKKKEKEEKEREEKLKEKERQ 930
Query: 514 VKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIE----NKQ 569
K KE K+ T E + K+ E+L+ + R E E K+K+K+ + K+
Sbjct: 931 EKLKEKEREEKLKRETEERQREKEREEKLKEKERAEKLKDLEKEVKLKEKEEQLKEKEKE 990
Query: 570 LKIKVSSAEAKSKKLYKTLLS 590
LK+K + K K+ K+L S
Sbjct: 991 LKLKEKKEKDKVKEKEKSLES 1011
>Hs15313972 [Z] KOG0161 Myosin class II heavy chain
Length = 1647
Score = 55.8 bits (133), Expect = 2e-07
Identities = 65/299 (21%), Positives = 126/299 (41%), Gaps = 46/299 (15%)
Query: 298 LTKQNEQLQQINEGYL-TKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKDL-VRI 355
+T+Q E+LQ +E L K +Q + E+ + + L ++ + E +L
Sbjct: 518 VTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEA 577
Query: 356 RTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQDALMKELQD 415
+R L AK LE E+L DLE + ++E+ Q ++ + + +QD
Sbjct: 578 EEMRARLAAKKQELE------EILHDLESRVEEEEERNQILQNEKKK------MQAHIQD 625
Query: 416 LEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXX 475
LE+ E +E KL +EK A K + ++ I++
Sbjct: 626 LEEQLDE--------------EEGARQKLQLEKVTAEAKI---KKMEEEILLLEDQNSKF 668
Query: 476 XXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKL 535
+K+ +K ++ +I QL+ +E K + + + + I +L K
Sbjct: 669 ----------IKE-KKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKE 717
Query: 536 KKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGD 594
+K+ + LE R L G T+L+ +I + + +LK+++ AK ++ + L+ G D
Sbjct: 718 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQL----AKKEEELQGALARGDD 772
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 55.5 bits (132), Expect = 3e-07
Identities = 86/412 (20%), Positives = 163/412 (38%), Gaps = 43/412 (10%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNER-------ELSELRQTVXXXXXXXXXXXXXX 280
E E ++L I LE T+ ++ + K+ E ELS L +T+
Sbjct: 945 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAH 1004
Query: 281 XXXXXPDASVTNEKISSLTKQNEQLQQINEGYLTKFQQ---LSADREIFNNKLTSEFNLA 337
D +K++SL K +L+Q E + +Q L D E KL + LA
Sbjct: 1005 QQALD-DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLA 1063
Query: 338 QET---LKKHNASLEKDLVRIRTIRDELLAKVSL-----LEAQKTKSEM---LEDLEKSL 386
QE+ L+ L++ L + +L +KV L+ QK E+ +E+LE+ +
Sbjct: 1064 QESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI 1123
Query: 387 NIQQEQLQKFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLT- 445
++ K E + S+ A +EL++L + E +++ + +E+ KL
Sbjct: 1124 EAERATRAKTEKQRSDYA------RELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR 1177
Query: 446 --VEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQ 503
E T E A +R K A + ++ + E L+ ++ M+
Sbjct: 1178 DLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 1237
Query: 504 -LSLSQENEKRV-----------KESNKETSMKIVELTSENNKLKKSTERLESETRNLIG 551
+S S+ N +++ + N+E + ELT++ ++L+ L +
Sbjct: 1238 SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKES 1297
Query: 552 TKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELE 603
++L + + ++LK ++ L L S+ D L E+ E
Sbjct: 1298 IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE 1349
Score = 52.0 bits (123), Expect = 3e-06
Identities = 83/403 (20%), Positives = 161/403 (39%), Gaps = 41/403 (10%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E +I ++ + E ELT K + E E SEL++ +
Sbjct: 917 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 976
Query: 288 ASVT------NEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETL 341
++T +E I+ LT++ + LQ+ ++ L Q D+ NK S+ E L
Sbjct: 977 KNLTEELSGLDETIAKLTREKKALQEAHQQALDDL-QAEEDKVNSLNKTKSKLEQQVEDL 1035
Query: 342 -------KKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQ 394
KK LE++ ++ D LA+ S+L+ + K ++ E L+K + + QLQ
Sbjct: 1036 ESSLEQEKKLRVDLERNKRKLE--GDLKLAQESILDLENDKQQLDERLKKK-DFEYCQLQ 1092
Query: 395 -KFESRSSENASQDALMKELQ----DLE---KAFREVSHLSNKKYAAYLNQESVLSKLTV 446
K E + +KELQ +LE +A R + K+ + Y + LS+
Sbjct: 1093 SKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLE 1152
Query: 447 EKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSL 506
E + + ++A + +V L K + + Q+
Sbjct: 1153 EAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMV--ATLRKKHADSVAELGEQIDN 1210
Query: 507 SQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIE 566
Q ++++++ E ++I +L+S + KS LE R LE ++ + +
Sbjct: 1211 LQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRT-------LEDQLSEARGK 1263
Query: 567 NKQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELENFRTII 609
N++++ +S + +L + G L+ +LE +I+
Sbjct: 1264 NEEIQRSLSELTTQKSRLQT-------EAGELSRQLEEKESIV 1299
Score = 51.2 bits (121), Expect = 5e-06
Identities = 73/423 (17%), Positives = 160/423 (37%), Gaps = 25/423 (5%)
Query: 158 ATEYYENIIAQYDRQDSESVSRVFNTADDDSNVKKEKQSSTGAXXXXXXXXXXXXXXXXX 217
AT +E ++A ++ ++SV+ + D+ VK++ +
Sbjct: 1182 ATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSK 1241
Query: 218 XXXAVSQAHHEIE--INDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXX 275
+ + +E +++ + ++ ++ ELT K++ + E EL + +
Sbjct: 1242 SKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQ 1301
Query: 276 XXXXXXXXXXPDASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFN 335
T E L ++N+ + + RE + + +
Sbjct: 1302 LSRSKQAFTQQ----TEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAE 1357
Query: 336 LAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQK 395
L Q L K N+ + + + T D + L EAQ+ ++ L+D E+ + +
Sbjct: 1358 L-QRALSKANSEVAQWRTKYET--DAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCAS 1414
Query: 396 FESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKY 455
E ++ L E++DL + L+ N + VL++ + ++ +
Sbjct: 1415 LEK------TKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 1468
Query: 456 FAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVK 515
A+++ ++ + +K K L+Q+I ++ Q++ EN K +
Sbjct: 1469 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA---ENGKTIH 1525
Query: 516 ESNKETSMKIVELTSENNKLKKSTERLESETRNLIG-------TKTELESKIKDKDIENK 568
E K +E L+++ LE E ++ K+E++ KI +KD E +
Sbjct: 1526 ELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585
Query: 569 QLK 571
QLK
Sbjct: 1586 QLK 1588
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 55.1 bits (131), Expect = 3e-07
Identities = 85/397 (21%), Positives = 160/397 (39%), Gaps = 78/397 (19%)
Query: 224 QAHHEIEIND-----LNTQISVLEATVKELTEWKNQN---ERELSELRQTVXXXXXXXXX 275
Q H+E+++ D T L+ +KEL E NQ E +S++ +
Sbjct: 438 QLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINE 497
Query: 276 XXXXXXXXXXPDASVTNEKISSLTKQNEQLQQINEGYLT---KFQQLSADREIFNNKLTS 332
+V NE +S+L Q E L+++++ K QL E N+ L +
Sbjct: 498 YQRKAEQENEKRRNVENE-VSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRT 556
Query: 333 EFNLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTK----------------- 375
E + A L+K + + K + ++ ++ EL + +LE K++
Sbjct: 557 ESDTAVR-LRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERR 615
Query: 376 -----SEMLEDLEKSLNIQQEQLQKFESRSSENASQDALMKELQDL------EKAFREVS 424
SEM+ DL+ + QE+++ + + + KE QD+ EK E+
Sbjct: 616 DRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGE---RKEAQDMLNHSEKEKNNLEID 672
Query: 425 HLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIV 484
L+ K + E +++ V K + ++K+ + +K M
Sbjct: 673 -LNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMC----------------- 714
Query: 485 QLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKST---ER 541
++EK L++ + ++ E RV + K+ SM V+L KL+ T ER
Sbjct: 715 ---EMEKKLKE-------EREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKER 764
Query: 542 LESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAE 578
+E E +NL +LE + + + +LK + A+
Sbjct: 765 MEDEVKNL---TLQLEQESNKRLLLQNELKTQAFEAD 798
>YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 1312
Score = 54.7 bits (130), Expect = 4e-07
Identities = 78/311 (25%), Positives = 132/311 (42%), Gaps = 61/311 (19%)
Query: 297 SLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKDLVRIR 356
S+ + ++LQ+I E K Q S R++F LT EF A LE D ++
Sbjct: 540 SINTKLDELQKITE----KLQNDSRIRQVF--PLTQEFQ---------RADLEMDFQKLF 584
Query: 357 TIRDELLA----KVSLLEAQKTKSEM-LEDLEKSLNIQQEQLQKFESRSSENASQDALMK 411
+ +A K+ L+ + T + L +EK L Q+ +K SEN +D +
Sbjct: 585 INMQKNIAINNKKMHELDRRYTNALYNLNTIEKDLQDNQKSKEKVIQLLSENLPEDCTID 644
Query: 412 E----LQDLEKAF-----------------REVSHLSNKKYAAYL-----NQESVLSKLT 445
E L++ E ++ R+ ++ + YL ES SKL
Sbjct: 645 EYNDVLEETELSYKTALENLKMHQTTLEFNRKALEIAERDSCCYLCSRKFENESFKSKLL 704
Query: 446 VE-KTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQL 504
E KTK + + KD + + L+ LEK + + +++ ++
Sbjct: 705 QELKTKTDANFEKTL--KDTVQ-----------NEKEYLHSLRLLEKHIIT-LNSINEKI 750
Query: 505 SLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKD 564
SQ+ ++ KE K + K+ EL ++ KLK E ESE R LI T LE ++KD +
Sbjct: 751 DNSQKCLEKAKEETKTSKSKLDELEVDSTKLKDEKELAESEIRPLIEKFTYLEKELKDLE 810
Query: 565 IENKQLKIKVS 575
+K + ++S
Sbjct: 811 NSSKTISEELS 821
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 54.7 bits (130), Expect = 4e-07
Identities = 69/369 (18%), Positives = 157/369 (41%), Gaps = 32/369 (8%)
Query: 237 QISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPDASVTNE--- 293
+I LE V++L N + E++EL+ + SV N+
Sbjct: 1289 KIQELEKEVEKLNASLNPLQTEINELKAEIGAKTASLNLMKEYNSRWKLRFQSVLNKYER 1348
Query: 294 ----KISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLE 349
++ L K E L++ + TK Q+ + + + F ++ S L + +L+
Sbjct: 1349 VDPTQLEELKKNCEALEKEKQELETKLQETAKETDTFKQQVNS--------LNEEVENLK 1400
Query: 350 KDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQDAL 409
K++ + T L A + +K ++ L + +++QE K + +S+NA +A+
Sbjct: 1401 KEVEQANTKNTRLAAAWN----EKCENLKKSSLTRFAHLKQELTNKNKELTSKNAENEAM 1456
Query: 410 MKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTK---ASEKYFAAMRSKDAIM 466
KE++ L+ + ++ ++ ++ K E+T+ A K +A+
Sbjct: 1457 QKEIESLKDSNHQLQESASSDAEQITKEQFEQLKSEKERTEKELADSKNELEHLQSEAV- 1515
Query: 467 IXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIV 526
I +L+ ++ L Q++ N+ +L+ +E+ + + E + +I
Sbjct: 1516 --DADGKTEISNLEKEIHELRSDKEGLVQQVQNLSAELAALREHSP--TQGSLENADEIA 1571
Query: 527 ELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYK 586
L S+ K+ E+ E ET ++ ++EL + +K+ ++L+ +++ + K+L +
Sbjct: 1572 RLRSQLESTKQYYEK-EKET-EILAARSEL---VAEKEKTKEELENQLNEKSQRIKELEE 1626
Query: 587 TLLSNGGDN 595
N +N
Sbjct: 1627 QAQKNSSEN 1635
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 54.7 bits (130), Expect = 4e-07
Identities = 94/436 (21%), Positives = 175/436 (39%), Gaps = 39/436 (8%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E +I ++ + E ELT K + E E SEL++ +
Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 288 ASVT------NEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETL 341
++T +E I+ LTK+ + LQ+ ++ L L A+ + N ++ L Q+
Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTL---DDLQAEEDKVNTLTKAKIKLEQQV- 1035
Query: 342 KKHNASLEKDLVRIRTIRDEL-LAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRS 400
LE L + + IR +L AK L K E D+E E+L+K E
Sbjct: 1036 ----DDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEM 1091
Query: 401 S--------ENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKAS 452
S E A L K++++L+ E+ + A+ E S L+ E + S
Sbjct: 1092 SGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS 1151
Query: 453 EKYFAAMRSKDAIMIXXXXXXXXXXXXXXXI----VQLKDLEKTLQQKIVNVHMQLSLSQ 508
E+ A + A + + +Q + TL++K + +L
Sbjct: 1152 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1211
Query: 509 ENEKRVKE----SNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDK- 563
+N +RVK+ E M+I +L S + K+ LE R L +E+++K +++
Sbjct: 1212 DNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQ 1271
Query: 564 ----DIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNG--ALAEELENFRTIIYCSLCSKN 617
D+ ++ +++ S E + K L + G A +++E + + + +K+
Sbjct: 1272 RLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKS 1331
Query: 618 WKNTALKTCGHVFCDV 633
AL++ H CD+
Sbjct: 1332 ALAHALQSSRH-DCDL 1346
>Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2349
Score = 54.3 bits (129), Expect = 6e-07
Identities = 61/301 (20%), Positives = 137/301 (45%), Gaps = 32/301 (10%)
Query: 287 DASVTNEKISSLTKQNEQLQQINEGYLTKF----QQLSADREIFNNKLTSEFNLAQ--ET 340
+ S E+++ L NE LQ+ E LTK +Q ++ E F+N+L + L+ ++
Sbjct: 232 EVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKS 291
Query: 341 LKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLN-IQQEQLQKFESR 399
+ + +L R +LL + EA K + L ++E+S + +++E L+K
Sbjct: 292 AADDSEAKSNELTRAVEELHKLLKEAG--EANKAIQDHLLEVEQSKDQMEKEMLEKIGRL 349
Query: 400 SSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAM 459
E + + L+ + R+ + LS ++ AA + ++K+ K +E Y A +
Sbjct: 350 EKELENANDLLSATK------RKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYV 403
Query: 460 RSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQ---LSLSQENEKRVKE 516
++D +++ ++ K + K L + + V + L +E +R ++
Sbjct: 404 ETQDQLLLEK--------------LENKRINKYLDEIVKEVEAKAPILKRQREEYERAQK 449
Query: 517 SNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSS 576
+ S+K+ + E +L++ T++ ++ L +E ++KD + + L +++
Sbjct: 450 AVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEE 509
Query: 577 A 577
A
Sbjct: 510 A 510
Score = 51.2 bits (121), Expect = 5e-06
Identities = 59/293 (20%), Positives = 121/293 (41%), Gaps = 39/293 (13%)
Query: 329 KLTSEFNLAQET---LKKHNASLEKDLVRIRT-IRDELLAKVSLLEAQKTKSEMLEDLEK 384
K T N+ ET L++ LE+DL +++ +R L + L EA SE L+
Sbjct: 1264 KKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQA 1323
Query: 385 SLNIQQEQLQKFESRSSENASQ----------------DALMKELQDLEKAFREVSHLSN 428
+ +E ++++++R+ SQ + K +Q L + +
Sbjct: 1324 EKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIA 1383
Query: 429 KKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXX----IV 484
+ A+ N ++++ L + K + + DA +I
Sbjct: 1384 RSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKT 1443
Query: 485 QLKDLEKTLQQKIVNV-------HMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKK 537
Q ++L K Q K++ H + +S + + +KE+ + K L S+ L+K
Sbjct: 1444 QYEEL-KAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQK 1502
Query: 538 STERLESETRNLIGTKTELESK-------IKDKDIENKQLKIKVSSAEAKSKK 583
+ E+E RNL +L+S+ ++D+ + +QL+ +++ E K++K
Sbjct: 1503 TLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRK 1555
>Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1427
Score = 53.9 bits (128), Expect = 8e-07
Identities = 80/396 (20%), Positives = 165/396 (41%), Gaps = 61/396 (15%)
Query: 228 EIEINDLNTQISVLEATVKELT--------EWKNQNERELSELRQTVXXXXXXXXXXXXX 279
++++ N S L+ +++++T E ++E E EL + +
Sbjct: 951 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 1010
Query: 280 XXXXXXPDASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQE 339
T+E + TK E LQ + + L +L RE + L L ++
Sbjct: 1011 CQELKARYERATSE---TKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQ 1067
Query: 340 TLKKHNASLEKDLVRI--RTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFE 397
K A +D ++I + +++ SL + ++T +++ +L+ +++ L+ E
Sbjct: 1068 ADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELD---TLKENNLKNVE 1124
Query: 398 SRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFA 457
N S++ L E Q +E+ +E+ L K+ AA +Q+ LS L E K +E+
Sbjct: 1125 EL---NKSKELLTVENQKMEEFRKEIETL--KQAAAQKSQQ--LSALQEENVKLAEELG- 1176
Query: 458 AMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKES 517
RS+D ++ +K +++ V + L + + K +K++
Sbjct: 1177 --RSRD---------------------EVTSHQKLEEERSVLNNQLLEMKKRESKFIKDA 1213
Query: 518 NKE----------TSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIEN 567
++E TS + E +E KL+ L E + L S ++ + +
Sbjct: 1214 DEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN----ASAKSLHSVVQTLESDK 1269
Query: 568 KQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELE 603
+L++KV + E + K+ + L S+ G+ A+E E
Sbjct: 1270 VKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDE 1305
Score = 52.8 bits (125), Expect = 2e-06
Identities = 67/288 (23%), Positives = 118/288 (40%), Gaps = 22/288 (7%)
Query: 288 ASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFN--NKLTSEFNLAQETLKKHN 345
AS+ + K ++ QNE L + E L ++L+ +E+ N+ EF ETLK+
Sbjct: 1096 ASLEDTKQTNAKLQNE-LDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAA 1154
Query: 346 ASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENAS 405
A + L ++ +L ++ + T + LE+ LN Q +++K ES+ ++A
Sbjct: 1155 AQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDAD 1214
Query: 406 QDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAI 465
+ E L+K+ S L +K ++ L KL E T + +A +
Sbjct: 1215 E-----EKASLQKSISITSALLTEK-------DAELEKLRNEVTVLRGENASAKSLHSVV 1262
Query: 466 MIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKI 525
+QLK+ ++ L N Q + E+E+ + + I
Sbjct: 1263 QTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQ---ADEDERAQESQIDFLNSVI 1319
Query: 526 VELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIK 573
V+L +N LK E + N G +L + D D + KQ K K
Sbjct: 1320 VDLQRKNQDLKMKVEMMSEAALN--GNGDDLNN--YDSDDQEKQSKKK 1363
Score = 50.4 bits (119), Expect = 8e-06
Identities = 67/337 (19%), Positives = 141/337 (40%), Gaps = 35/337 (10%)
Query: 292 NEKISSLTKQNEQLQQINEGYLT--KFQQLSADREIFNNKLTSEFNLAQETLK----KHN 345
NE+ + QL+ E L ++ S++ + KL + A++ +K + N
Sbjct: 742 NEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKN 801
Query: 346 ASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENAS 405
A K R ++ L +L E S++ E LEK L I +E KF S E S
Sbjct: 802 AESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKE---KFAEASEEAVS 858
Query: 406 QDALMKE-LQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDA 464
M+E + L + + + LS+ N + +K EK + E+ +++K+
Sbjct: 859 VQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFR-EKDEREEQL---IKAKEK 914
Query: 465 IMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMK 524
+ + ++ D + ++ + + ++L+ + EN +++S ++ ++K
Sbjct: 915 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974
Query: 525 IVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKL 584
+ E + ++ E E + L ++LE K++ + ++LK + A +++K
Sbjct: 975 AEQSQQE------AAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTK 1028
Query: 585 YKTLLSN---------------GGDNGALAEELENFR 606
++ +L N +N L +ELE R
Sbjct: 1029 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELR 1065
>At2g33240 [Z] KOG0160 Myosin class V heavy chain
Length = 1611
Score = 53.9 bits (128), Expect = 8e-07
Identities = 62/273 (22%), Positives = 123/273 (44%), Gaps = 29/273 (10%)
Query: 337 AQET--LKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQ 394
A+ET L+ LEK++ + + + L K +E ++ K++ +EDL +LN + QL
Sbjct: 910 AKETGALQDAKTKLEKEVEELTSCLE--LEKQMRMELEQVKTQEVEDLRSALNDMKLQLG 967
Query: 395 KFESRSSENASQDALMKELQDLEKAFREVS---HLSNKKYAAYLNQESVLSKLTVEKTKA 451
+ + SE + L LQD++ F E++ ++N A + ++S L + ++
Sbjct: 968 ETQVTKSEEILK--LQSALQDMQLEFEELAKELEMTNDLAAENEQLKDLVSSLQRKIDES 1025
Query: 452 SEKY-----FAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVN------- 499
KY + R K + + +LK L TL++KI +
Sbjct: 1026 DSKYEETSKLSEERVKQEVPVIDQGVIIKLEAENQ---KLKALVSTLEKKIDSLDRKHDD 1082
Query: 500 -VHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELES 558
V + E EK+ +E++K ++ ++ K ++++ E + ++ T E+
Sbjct: 1083 LVDLLERKIDETEKKYEEASKLCEERLKQVVDTEKKYEEASRLCEERLKQVVDT----ET 1138
Query: 559 KIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSN 591
K+ + ++L+ KVS EA+ K L + L N
Sbjct: 1139 KLIELKTSMQRLEEKVSDMEAEDKILRQQALRN 1171
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 53.9 bits (128), Expect = 8e-07
Identities = 75/339 (22%), Positives = 148/339 (43%), Gaps = 47/339 (13%)
Query: 292 NEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQE------TLKKH- 344
N+K+ SL KQ +++Q + Q+L + + S+ ++ TL+KH
Sbjct: 555 NDKVVSLEKQLLEMEQSYKTETENTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQKHK 614
Query: 345 ------NASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFES 398
NA L+ +V+ + +R +L K EA+ ++ D+E+++ +EQ + ++
Sbjct: 615 EELGQENAELQALVVQEKNLRSQL--KEMHKEAENKMQTLINDIERTMC--REQKAQEDN 670
Query: 399 RSSENASQDALMKELQDLEKAF---------------REV-SHLSNKKYAAYLNQESVLS 442
R AL++++ DLEKA +EV +H +K +E+ L
Sbjct: 671 R--------ALLEKISDLEKAHAGLDFELKAAQGRYQQEVKAHQETEKSRLVSREEANLQ 722
Query: 443 KLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVH- 501
++ ++K +E+ A +++ ++L+ LE +Q+ V
Sbjct: 723 EVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLEGECRQESEKVAA 782
Query: 502 MQLSLSQENEKR---VKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELES 558
+Q L QE+ KR + E + +S ++ L S N+L+K R T+L+S
Sbjct: 783 LQSQLDQEHSKRNALLSELSLHSS-EVAHLRSRENQLQKELSTQREAKRRFEEDLTQLKS 841
Query: 559 KIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGA 597
+ N++L+ ++ AE +LYKT + + A
Sbjct: 842 THHEALANNRELQAQL-EAEQCFSRLYKTQANENREESA 879
>YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1679
Score = 53.5 bits (127), Expect = 1e-06
Identities = 81/367 (22%), Positives = 152/367 (41%), Gaps = 58/367 (15%)
Query: 230 EINDLNTQISVLEATVKELTE-----WKNQNER--ELSELRQTVXXXXXXXXXXXXXXXX 282
++N L ++L+ ++K +TE +K N+R E+S L++ +
Sbjct: 1172 QVNILKENNAILQKSLKNVTEKNREIYKQLNDRQEEISRLQRDLIQTKEQVSINSNKILV 1231
Query: 283 XXXPDASVTNEKISSLTKQNEQLQQIN-----------EGYLTKFQQLSADREIFNNKLT 331
+ ++ L++Q + Q+ + +G L+ + +AD E N+L
Sbjct: 1232 YES-EMEQCKQRYQDLSQQQKDAQKKDIEKLTNEISDLKGKLSSAENANADLENKFNRLK 1290
Query: 332 SEFNLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQE 391
+ + + KK A+L +L ++ I+D+L L + K L+ K+ +Q E
Sbjct: 1291 KQAHEKLDASKKQQAALTNELNELKAIKDKLEQD---LHFENAKVIDLDTKLKAHELQSE 1347
Query: 392 QLQKFESRSSENASQDALMKELQDLEK---AFREVSHLSNKKYAAYLNQESVLSKLTVEK 448
+ SR E + LM+E++ L+K F+ + S+ +N E ++ E+
Sbjct: 1348 DV----SRDHEKDTYRTLMEEIESLKKELQIFKTANSSSDAFEKLKVNMEKEKDRIIDER 1403
Query: 449 TKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQ 508
TK EK +K KD+E TL+++ + +
Sbjct: 1404 TKEFEKKLQETLNK---------------STSSEAEYSKDIE-TLKKEWLKEY-----ED 1442
Query: 509 ENEKRVKESNKETSMKIVELTSENNKLK---KSTERLESETRNLI----GTKTELESKIK 561
E +R+KE+ +E K + L SE K K E LE E R + G+ T L++K
Sbjct: 1443 ETLRRIKEA-EENLKKRIRLPSEERIQKIISKRKEELEEEFRKKLKENAGSLTFLDNKGS 1501
Query: 562 DKDIENK 568
+D E +
Sbjct: 1502 GEDAEEE 1508
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 53.5 bits (127), Expect = 1e-06
Identities = 69/298 (23%), Positives = 132/298 (44%), Gaps = 40/298 (13%)
Query: 291 TNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEK 350
+ +I L ++NE L Q L + Q+SA+ + + E + E++K+ ++ L K
Sbjct: 474 SERQIKILEQENEHLNQTVSS-LRQRSQISAEARV--KDIEKENKILHESIKETSSKLSK 530
Query: 351 DLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNI---QQEQLQKFESRSSENASQ- 406
R I+ EL E K K E E+LE L+ + E LQK + +
Sbjct: 531 IEFEKRQIKKEL-------EHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI 583
Query: 407 DALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIM 466
+AL +E +LE+ R++ K ++ N L L E ++ E+ R+ +++
Sbjct: 584 EALEQENSELERENRKLK----KTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 639
Query: 467 IXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIV 526
+ QL+ K L+ + + L L + + K K E S + +
Sbjct: 640 CASMK-----------MAQLQLENKELESEKEQLKKGLELLKASFK--KTERLEVSYQGL 686
Query: 527 ELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKL 584
++ EN +L+K+ E + + +LES+++D ++EN+ L+ + + SK+L
Sbjct: 687 DI--ENQRLQKTLENSNKKIQ-------QLESELQDLEMENQTLQKNLEELKISSKRL 735
>CE03665 [Z] KOG0161 Myosin class II heavy chain
Length = 1968
Score = 53.1 bits (126), Expect = 1e-06
Identities = 92/425 (21%), Positives = 161/425 (37%), Gaps = 48/425 (11%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E E DL ++ +++++ KN E ++ L+ + +
Sbjct: 960 EAECADLKKNCQDVDLSLRKVEAEKNAKEHQIRALQDEMRQQDENISKLNKERKNQEEQN 1019
Query: 288 ASVTNEKISSLTKQNEQLQQI----------NEGYLTKFQQLSADREIFNNKLTSEFNLA 337
+T E + + +QN ++ +E + + ++ AD + K E +A
Sbjct: 1020 KKLT-EDLQAAEEQNLAANKLKAKLMQSLEDSEQTMEREKRNRADMDKNKRKAEGELKIA 1078
Query: 338 QETLKKHNAS---LEKDLVRIRT--------IRDELLAKVSLLEAQKTKSEMLEDLEKSL 386
QETL++ N S E L R T + DE A L + + ++DL L
Sbjct: 1079 QETLEELNKSKSDAENALRRKETELHTLGMKLEDEQAAVAKLQKGIQQDEARVKDLHDQL 1138
Query: 387 NIQQEQLQKFE-SRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLN-----QESV 440
+++ Q+ + SR+ + A D L ++L+D +A L KK A +ES
Sbjct: 1139 ADEKDARQRADRSRADQQAEYDELTEQLEDQARATAAQIELGKKKDAELTKLRRDLEESG 1198
Query: 441 L---SKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKI 497
L +LTV K K S DAI + +++ +
Sbjct: 1199 LKFGEQLTVLKKKGS----------DAIQELSDQIEQLQKQKGRIEKEKGHMQREFDESS 1248
Query: 498 VNVHMQLSLSQENEKRVKESN---KETSMKIVELTSENNKLKKSTERLESETRNLIGTKT 554
+ + L + E+ K E +K E + + S RL SE +L
Sbjct: 1249 AALDQEAKLRADQERIAKGYEVRLLELRLKADEQSRQLQDFVSSKGRLNSENSDLARQVE 1308
Query: 555 ELESKIKDKDIENKQLKIKVSSA--EAKSKKLYKTLLSNGGDNGALAEELENFRTIIYCS 612
ELE+KI+ + Q ++ A +A+ + + LSN N LA ELE + I
Sbjct: 1309 ELEAKIQAANRLKLQFSNELDHAKRQAEEESRERQNLSNLSKN--LARELEQLKESIEDE 1366
Query: 613 LCSKN 617
+ KN
Sbjct: 1367 VAGKN 1371
>At1g03830 [R] KOG2037 Guanylate-binding protein
Length = 991
Score = 53.1 bits (126), Expect = 1e-06
Identities = 74/398 (18%), Positives = 152/398 (37%), Gaps = 37/398 (9%)
Query: 238 ISVLEATVKELTEWKNQNERELSE-----LRQTVXXXXXXXXXXXXX---XXXXXXPDAS 289
+ VL +T E +EWK + E L E +R V +
Sbjct: 475 MEVLGSTRLEASEWKRKYEGTLDENGVSNIRVGVDASITRCSNKLIDWKIKYENTVSEQK 534
Query: 290 VTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLE 349
EKI+++ ++ +Q +G +F ++ ++E + ++ ++ L A L+
Sbjct: 535 AVTEKIAAMEEKLKQASTTEDGLRAEFSRVLDEKEKIITEKAAKLATLEQQLASTRAELK 594
Query: 350 KDLVRIRTIRDE---LLAKVSLL----EAQKTKSEMLE-----------DLEKSLNIQQE 391
K +++ E + ++SLL E+ K+ SE+LE +L+K +I E
Sbjct: 595 KSALKVDECSSEAKDVRLQMSLLNEKYESVKSASELLETETETLKREKDELDKKCHIHLE 654
Query: 392 QLQKFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKA 451
+L+K R + S+ K+L D K E + + K L + + + +
Sbjct: 655 ELEKLVLRLTNVESEALEAKKLVDSLKLEAEAARDNENKLQTSLVERCIEIDRAKSRIEE 714
Query: 452 SEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENE 511
EK + L+ L+ K + + +
Sbjct: 715 LEKVCTLNSGEGEASASKKLVDSMKMEAEASRKNENKLQTLLEDKCIEI--------DRA 766
Query: 512 KRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLK 571
K E + +K+ SE +K+ ++ E + + +L+ +++K IE + K
Sbjct: 767 KSRIEGLERDCLKLKYAESEAATVKELVSSMKMEVESARSNEKKLQLSLQEKTIEIDRAK 826
Query: 572 IKVSSAEAKSKKLYKTLLSNGGDNGALAEELENFRTII 609
++ + E + +L +TL + N EE+ ++ II
Sbjct: 827 GQIEALERQKMELSETLETRAKQN---EEEVTKWQRII 861
>Hs20558376 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 52.0 bits (123), Expect = 3e-06
Identities = 79/377 (20%), Positives = 155/377 (40%), Gaps = 32/377 (8%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E +I ++ + E ELT K + E E SEL++ +
Sbjct: 919 EAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 978
Query: 288 ASVT------NEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQ--- 338
++T +E I+ L+K+ + LQ+ ++ L L A+ + N ++ L Q
Sbjct: 979 KNLTEEMAGLDETIAKLSKEKKALQETHQQTL---DDLQAEEDKVNILTKAKTKLEQQVD 1035
Query: 339 --ETLKKHNASLEKDLVRI-RTIRDEL-LAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQ 394
E + L DL R R + +L LA+ S ++ + K ++ E LEK +
Sbjct: 1036 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLIS 1095
Query: 395 KFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEK 454
K E E A + L K++++L+ E+ + A+ E S L+ E + SE+
Sbjct: 1096 KIE---DEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISER 1152
Query: 455 YFAAMRSKDAIMIXXXXXXXXXXXXXXXI----VQLKDLEKTLQQKIVNVHMQLSLSQEN 510
A + A + + +Q + + L++K + +L +N
Sbjct: 1153 LEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDN 1212
Query: 511 EKRVKE----SNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDK--- 563
+RVK+ E M+ +L+S + K+ LE R+L +EL++K +++
Sbjct: 1213 LQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRL 1272
Query: 564 --DIENKQLKIKVSSAE 578
D+ ++ +++ + E
Sbjct: 1273 INDLTAQRARLQTEAGE 1289
>7303173 [DY] KOG0977 Nuclear envelope protein lamin intermediate filament
superfamily
Length = 621
Score = 52.0 bits (123), Expect = 3e-06
Identities = 72/338 (21%), Positives = 141/338 (41%), Gaps = 50/338 (14%)
Query: 289 SVTNEKISSLTKQNEQLQQINEG---YLTKFQQLSADREIFNNKLTSEFNLAQETLKKHN 345
S T+ +S ++ E+LQ +N+ Y+ + + L + N++LT E NLAQ+T+ +
Sbjct: 34 SPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENE----NSRLTQELNLAQDTVNRET 89
Query: 346 ASL----EKDLVRIRTIRDELLAKVSLLEA-----------------QKTK--------S 376
++L EK+L R + DE + + LE +KTK +
Sbjct: 90 SNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNA 149
Query: 377 EMLEDLEKSLNIQQEQ----LQKFESRSSENA-SQDALMKELQDLEKAFREVSHLSNKKY 431
+ E+ +N + Q +KFE ++ E A + L ++L DL K E L+
Sbjct: 150 RLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQL-EAETLARVDL 208
Query: 432 AAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEK 491
NQ L + K + + RS+ I I L++L
Sbjct: 209 E---NQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRD 265
Query: 492 TLQQKIVNVHMQLSLSQENE-KRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLI 550
+ ++ ++ L +NE + +K + + T E ++ + L ++ +NL
Sbjct: 266 QYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLE 325
Query: 551 GTKTELESKIKD----KDIENKQLKIKVSSAEAKSKKL 584
T L ++I++ D E ++ ++S EA+ +++
Sbjct: 326 DTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRM 363
>SPBC3D6.04c [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 689
Score = 51.6 bits (122), Expect = 4e-06
Identities = 67/321 (20%), Positives = 137/321 (41%), Gaps = 26/321 (8%)
Query: 298 LTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKDLVRIRT 357
LT +QL++ + Y + +++ ++E K+ + + + + +EK+ +
Sbjct: 103 LTLVEKQLEEQSTSYQKEIEEVRNEKEATQVKIHELLDAKWKEIAELKTQIEKNDQALSE 162
Query: 358 IRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQDALMKEL---- 413
E++ L+ + T L +LEK +EQL E++ E A+ + ++EL
Sbjct: 163 KNHEVMVSNQALQMKDTN---LTNLEKLFADSREQL---ETKCKELAAAEQQLQELSVHN 216
Query: 414 QDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKAS-EKYFAAMRSKDAIMIXXXXX 472
Q LE++ ++VS + +N E L +EK KA+ E+ + S + +
Sbjct: 217 QQLEESIKQVSSSIELEK---INAEQRLQISELEKLKAAQEERIEKLSSNNRNVEILKEE 273
Query: 473 XXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSEN 532
+ +D TL+ + + +L+ + + + S K+V L + N
Sbjct: 274 KNDLESKLYRFEEYRDKVATLELENEKIQTELNSWKSLITNELPTPEAVSNKLVFLQNTN 333
Query: 533 NKLKKSTERLESETRNLIGTK------------TELESKIKDKDIENKQLKIKVSSAEAK 580
L + LES+ N + TELE+K+K+ +N++L+ + S A +
Sbjct: 334 ANLGERVSSLESQLSNKPANQPLGANEKDAAHITELETKLKELHEQNRRLQRQKSLATQE 393
Query: 581 SKKLYKTLLSNGGDNGALAEE 601
L + L S + L+E+
Sbjct: 394 IDLLRENLKSYDDEEAILSEK 414
>Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2871
Score = 51.6 bits (122), Expect = 4e-06
Identities = 85/418 (20%), Positives = 143/418 (33%), Gaps = 64/418 (15%)
Query: 247 ELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPDASVTNEKISSLTKQNEQLQ 306
EL + +N E+S LR D+ ++ L+++N L+
Sbjct: 1191 ELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLK 1250
Query: 307 ----QINEGYL-----------TKFQQLSADREIFNNKLTSEFNLAQ------ETLKKHN 345
++N+ L QQ + EI K E L Q E +H
Sbjct: 1251 DEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHK 1310
Query: 346 ASLEKDLVRIRTIRDEL-LAKVSLLEAQKTKSEMLEDLEKSLN----------------- 387
SLE+ I+ E+ K E K + E +L K N
Sbjct: 1311 QSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEI 1370
Query: 388 ------IQQEQLQKFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVL 441
I Q +QK E S A D L +E + L + E+ L N N V
Sbjct: 1371 NITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSE---EIKRLKNTLTQTTENLRRVE 1427
Query: 442 SKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVH 501
+ +K SE + R + + L D KT+Q K +
Sbjct: 1428 EDIQQQKATGSE---VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIE 1484
Query: 502 M--QLSLSQENEKRVKESNKETSMKI-VELTSENNKLKKSTERLESETRNLIGTKTELES 558
QL + N+++ E ++ +L N+ ++ +L+ + + L + + E
Sbjct: 1485 RLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYER 1544
Query: 559 -----KIKDKDIEN-----KQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELENFR 606
+KD+DI K+L+++ E + +L +T + L EELE R
Sbjct: 1545 VSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMR 1602
>Hs9055284 [Z] KOG0160 Myosin class V heavy chain
Length = 1742
Score = 51.2 bits (121), Expect = 5e-06
Identities = 69/335 (20%), Positives = 138/335 (40%), Gaps = 45/335 (13%)
Query: 293 EKISSLTKQNEQLQQINEGYLTKFQQLSAD---------REIFNN---------KLTSEF 334
EK++ L K N +L+ E K Q+ + + +++F++ L F
Sbjct: 956 EKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSF 1015
Query: 335 NLAQETLKKHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQ 394
L + +K SL+++ I+ ++DE + L+E + S+ L+ L+ Q + +
Sbjct: 1016 ELKTQDYEKQIQSLKEE---IKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTIS 1072
Query: 395 KFESR-SSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEK----T 449
+FE A + + K +Q ++ RE K+ + E V S+L+VE
Sbjct: 1073 EFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLN 1132
Query: 450 KASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQE 509
+ E +FA K A + I + L K+V++ +++ Q+
Sbjct: 1133 EDGELWFAYEGLKKATRVLESHFQSQKDCYEKEI-------EALNFKVVHLSQEINHLQK 1185
Query: 510 NEKRVKESNKETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESKIKDKDIE-NK 568
+ + N+ ++ LTSEN + +++ +ELE + +D +I N+
Sbjct: 1186 LFREENDINESIRHEVTRLTSENMMIPDFKQQI-----------SELEKQKQDLEIRLNE 1234
Query: 569 QLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEELE 603
Q + E S +L+++ G AL + E
Sbjct: 1235 QAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE 1269
>7291892 [Z] KOG0161 Myosin class II heavy chain
Length = 2056
Score = 51.2 bits (121), Expect = 5e-06
Identities = 81/391 (20%), Positives = 151/391 (37%), Gaps = 57/391 (14%)
Query: 228 EIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXXXPD 287
E NDL+ ++ E K L + K ++E +SEL + +
Sbjct: 1088 EERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERL--------------------- 1126
Query: 288 ASVTNEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNAS 347
+++Q +Q ++ K + AD + N+ + + Q L K
Sbjct: 1127 ------------HKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEE 1174
Query: 348 LEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFES-RSSENASQ 406
L + L+R I +E K + +AQ+ L ++++ L ++ K E R +
Sbjct: 1175 LTQTLLR---IDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEEL 1231
Query: 407 DALMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIM 466
+AL EL D L +K+ + + L K E+T E A MR K +
Sbjct: 1232 EALKNELLDSLDTTAAQQELRSKRE----QELATLKKSLEEETVNHEGVLADMRHKHSQE 1287
Query: 467 IXXXXXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQL----SLSQENEKRVKESNK--- 519
+ + L+ + TL+ + ++ +L S QEN++R K++
Sbjct: 1288 LNSINDQLENLRKAKTV--LEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIA 1345
Query: 520 ETSMKIVELTSENNKLKKSTERLESETRNLIGTKTELESK----IKDKDIENKQLKIKVS 575
E +K+ E+ ++L++ +L+ E N+ E E K +K QL
Sbjct: 1346 ELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQ 1405
Query: 576 SAEAKSKK---LYKTLLSNGGDNGALAEELE 603
E ++++ L L + AL E+LE
Sbjct: 1406 LLEEETRQKLGLSSKLRQIESEKEALQEQLE 1436
Score = 50.4 bits (119), Expect = 8e-06
Identities = 80/409 (19%), Positives = 157/409 (37%), Gaps = 56/409 (13%)
Query: 225 AHHEIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXXXXX 284
A E E+ +I AT + + + E +L+E+++ +
Sbjct: 1169 AKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLS 1228
Query: 285 XPDASVTNEKISSL--TKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLK 342
++ NE + SL T ++L+ E Q+L+ ++ + + + +
Sbjct: 1229 EELEALKNELLDSLDTTAAQQELRSKRE------QELATLKKSLEEETVNHEGVLADMRH 1282
Query: 343 KHNASLEKDLVRIRTIRDELLAKVSLLEAQKTKSEMLEDLEKSLNIQQEQLQKFESRSSE 402
KH+ L ++ +R AK L +A+ T DL L Q+ + R +
Sbjct: 1283 KHSQELNSINDQLENLRK---AKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQ 1339
Query: 403 NASQDA-LMKELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRS 461
SQ A L +L ++E+A E+ K L QE+ +T + +A K AA++S
Sbjct: 1340 AESQIAELQVKLAEIERARSELQEKCTK-----LQQEA--ENITNQLEEAELKASAAVKS 1392
Query: 462 KDAIMIXXXXXXXXXXXXXXXIVQLKDLEKT-LQQKIVNVHMQLSLSQENEKRVKESNKE 520
+ +++ + +K L K+ + + QE + E+ +
Sbjct: 1393 ASNM--------ESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRN 1444
Query: 521 TSMKIVELTSENNKLKKSTER---------------------LESETRNLIG-------T 552
K+ E+T++ ++KK E LE + + LI +
Sbjct: 1445 YERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKS 1504
Query: 553 KTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEE 601
K +++S+++D IE + + KV E K K K L + +A+E
Sbjct: 1505 KKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQE 1553
>Hs4826748 [UR] KOG4677 Golgi integral membrane protein
Length = 731
Score = 50.8 bits (120), Expect = 6e-06
Identities = 70/339 (20%), Positives = 147/339 (42%), Gaps = 58/339 (17%)
Query: 292 NEKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKD 351
N++++SL +++++ Q+ + ++ +AD ++++T + L + A+ +
Sbjct: 242 NQEMASLLQRSKETQEELNKARARVEKWNADHSK-SDRMTRGLRAQVDDLTEAVAAKDSQ 300
Query: 352 L----VRIRTIRDELLAKVSLLEA-QKTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQ 406
L VR++ L + LEA Q KS +++D + ++Q + LQ + R E
Sbjct: 301 LAVLKVRLQEADQLLSTRTEALEALQSEKSRIMQDQSEGNSLQNQALQTLQERLHE---A 357
Query: 407 DALMKELQDLEKAFR------------------------EVSHLSNKKYAAYLNQESVLS 442
DA +K Q+ K + E + KK L Q+ L
Sbjct: 358 DATLKREQESYKQMQSEFAARLNKVEMERQNLAEAITLAERKYSDEKKRVDELQQQVKLY 417
Query: 443 KLTVEKTKAS-----EKYFAAMRSKDAIM--IXXXXXXXXXXXXXXXIVQLKDL--EKTL 493
KL +E +K +K ++SK+ ++ + ++L++L EK +
Sbjct: 418 KLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFEGLDSSTASSMELEELRHEKEM 477
Query: 494 QQKIVN-----VHMQLSLSQENEKR-------VKESNKETSMKIVELTSENNKLKKSTER 541
Q++ + +H S Q+ E + +E ++ +I + +L+ ER
Sbjct: 478 QREEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELETELER 537
Query: 542 LESE----TRNLIGTKTELESKIKDKDIENKQLKIKVSS 576
L+ E +L TK L+S+IKD+D E ++L+ ++++
Sbjct: 538 LKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRNQLTN 576
>CE12204 [Z] KOG0161 Myosin class II heavy chain
Length = 1992
Score = 50.8 bits (120), Expect = 6e-06
Identities = 88/422 (20%), Positives = 161/422 (37%), Gaps = 77/422 (18%)
Query: 233 DLNTQISVLEATVKELTEWKNQNERE-LSELRQTVXXXXXXXXXXXXXXXXXXXPDASVT 291
DL QIS L A E+ +WK + + E L++L + + + T
Sbjct: 1392 DLTRQISKLNA---EIQQWKARFDSEGLNKLEEI---------EAAKKALQLKVQELTDT 1439
Query: 292 NE----KISSLTKQNEQLQQ-----------------INEGYLTKFQQLSADREIFNNKL 330
NE KI+S K +L Q E + +F+ + A+ + + L
Sbjct: 1440 NEGLFAKIASQEKVRFKLMQDLDDAQSDVEKAAAQVAFYEKHRRQFESIIAEWKKKTDDL 1499
Query: 331 TSEFNLAQETLKKHNASLEKDLVRIRTIRDELLAKV--------SLLEAQKTKSEML--- 379
+SE + AQ + N L DL + +T DEL + SL + K ++ L
Sbjct: 1500 SSELDAAQ----RDNRQLSTDLFKAKTANDELAEYLDSTRRENKSLAQEVKDLTDQLGEG 1555
Query: 380 -------EDLEKSLNIQQEQLQKF--ESRSSENASQDALMKELQDLEKAFREVSHLSNKK 430
+ + + L +++E+LQK E+ ++ A + +++ ++ + E+ +K
Sbjct: 1556 GRSVAELQKIVRKLEVEKEELQKALDEAEAALEAEEAKVLRAQIEVSQIRSEIEKRIQEK 1615
Query: 431 YAAYLNQ--------ESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXX 482
+ N ES+ + L E TK E+ A+R K +
Sbjct: 1616 EEEFENTRRNHQRALESMQATLEAE-TKQKEE---ALRIKKKLESDINDLEIALDHANRA 1671
Query: 483 IVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTERL 542
+ K + + + Q+ Q + ++E + + L SE ++L + E
Sbjct: 1672 YADAQKTIKKYMETVQELQFQIEEEQRQKDEIREQFLASEKRNAILQSEKDELAQQAEAA 1731
Query: 543 ESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGALAEEL 602
E RN EL +N L VS+ + +KL LL+ + +A EL
Sbjct: 1732 ERARRNAEAECIELRE-------QNNDLNAHVSALTGQRRKLEGELLAAHAELEEIANEL 1784
Query: 603 EN 604
+N
Sbjct: 1785 KN 1786
>YFR031c [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1170
Score = 50.4 bits (119), Expect = 8e-06
Identities = 54/294 (18%), Positives = 130/294 (43%), Gaps = 5/294 (1%)
Query: 293 EKISSLTKQNEQLQQINEGYLTKFQQLSADREIFNNKLTSEFNLAQETLKKHNASLEKD- 351
+K + + KQ E +Q + ++T+ Q + S+ NL+ L +L+ +
Sbjct: 681 QKYNQIQKQIETIQA-DLNHVTEELQTQYATSQKTKTIQSDLNLSLHKLDLAKRNLDANP 739
Query: 352 LVRIRTIRDELLAKVSLLEAQ-KTKSEMLEDLEKSLNIQQEQLQKFESRSSENASQDALM 410
+I +E+L + E + KTK L+ ++ ++ ++ +++++S ++ L
Sbjct: 740 SSQIIARNEEILRDIGECENEIKTKQMSLKKCQEEVSTIEKDMKEYDSDKGSKLNE--LK 797
Query: 411 KELQDLEKAFREVSHLSNKKYAAYLNQESVLSKLTVEKTKASEKYFAAMRSKDAIMIXXX 470
KEL+ L K E S +KY + N E +L+ E ++S +++ +
Sbjct: 798 KELKLLAKELEEQESESERKYDLFQNLELETEQLSSELDSNKTLLHNHLKSIESLKLENS 857
Query: 471 XXXXXXXXXXXXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTS 530
+V ++ +++++++ +L+ + K+ ++ K + +++ +L
Sbjct: 858 DLEGKIRGVEDDLVTVQTELNEEKKRLMDIDDELNELETLIKKKQDEKKSSELELQKLVH 917
Query: 531 ENNKLKKSTERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKL 584
+ NK K +T +E +L LE ++I + I + + +SK+L
Sbjct: 918 DLNKYKSNTNNMEKIIEDLRQKHEFLEDFDLVRNIVKQNEGIDLDTYRERSKQL 971
>Hs13376757 [R] KOG1729 FYVE finger containing protein
Length = 310
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/302 (19%), Positives = 125/302 (40%), Gaps = 31/302 (10%)
Query: 368 LLEAQKTKSEMLEDLEKSLNIQQEQ---LQKFESRSSENASQDALMKELQDLEKAFREVS 424
L E +K + E+ ++LE + ++ E ++ E + E QD L+ Q LE EV
Sbjct: 9 LKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEK--QDTLVALRQQLE----EVK 62
Query: 425 HLSNKKYAAYLNQESVLSK----LTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXX 480
++ + + N ES L + +T + K ++ + + ++ +
Sbjct: 63 AINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSH 122
Query: 481 XXIVQLKDLEKTLQQKIVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLK---K 537
+L LQ ++ +H Q S ++ K KE + ++ ++ L+ +
Sbjct: 123 KLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQ 182
Query: 538 STERLESETRNLIGTKTELESKIKDKDIENKQLKIKVSSAEAKSKKLYKTLLSNGGDNGA 597
E L+ E R L K EL+ ++++ +++ + +S ++ K + + + + G
Sbjct: 183 QVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWL 242
Query: 598 LAEELENFRTIIYCSLCSKNWKNTALK----TCGHVFCDVCCKERLA-----ARMRKCPT 648
+E +C C K + + K CGH+FC+ C LA +R C +
Sbjct: 243 KDDEAT------HCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDS 296
Query: 649 CN 650
C+
Sbjct: 297 CH 298
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 50.4 bits (119), Expect = 8e-06
Identities = 85/445 (19%), Positives = 176/445 (39%), Gaps = 84/445 (18%)
Query: 222 VSQAHHEIEINDLNTQISVLEATVKELTEWKNQNERELSELRQTVXXXXXXXXXXXXXXX 281
+ +A + + +L+ ++ E+ + +LT+ K ++L EL++ +
Sbjct: 1279 MQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQ 1338
Query: 282 XXXXPDASVTNEKIS-----------SLTKQNEQLQQINEGYLTKFQQLSADREIFNNKL 330
D + E+ +L+K N ++ Q Y T Q + + E KL
Sbjct: 1339 SSRH-DCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKL 1397
Query: 331 TSEFNLAQETLKKHN---ASLEKDLVRIRTIRDELL--------AKVSLLEAQKTKSEML 379
A+E + N ASLEK R++ ++L+ A +L + Q+ ++L
Sbjct: 1398 AQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVL 1457
Query: 380 EDLEKSLNIQQEQLQKFESRSSENASQDALMKELQDLEKAFREVSHLSNKKYAAYLNQES 439
+ ++ L+ Q +L+ + S +L EL + A+ EV N +
Sbjct: 1458 AEWKQKLDESQAELEAAQKESR------SLSTELFKMRNAYEEVVDQLETLRRENKNLQE 1511
Query: 440 VLSKLTVEKTKASEKYFAAMRSKDAIMIXXXXXXXXXXXXXXXIVQLKDLEKTL---QQK 496
+S LT + + + A ++K + V L+++E +L + K
Sbjct: 1512 EISDLTEQIAETGKNLQEAEKTKKLV----------EQEKSDLQVALEEVEGSLEHEESK 1561
Query: 497 IVNVHMQLSLSQENEKRVKESNKETSMKIVELTSENNKLKKSTER--------LESETR- 547
I+ V ++LS + E K++E E +LK++++R L++E R
Sbjct: 1562 ILRVQLELS----------QVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRS 1611
Query: 548 --NLIGTKTELESKIKDKDIE----NKQL-----------------KIKVSSAEAKSKKL 584
+ + K ++E + + +I+ N+Q+ ++ + A ++ L
Sbjct: 1612 RNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDL 1671
Query: 585 YKTLLSNGGDNGALAEELENFRTII 609
+ L NG L EELE + +
Sbjct: 1672 KEQLAIVERRNGLLLEELEEMKVAL 1696
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.310 0.125 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,438,846
Number of Sequences: 60738
Number of extensions: 1103873
Number of successful extensions: 9452
Number of sequences better than 1.0e-05: 48
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 9041
Number of HSP's gapped (non-prelim): 276
length of query: 663
length of database: 30,389,216
effective HSP length: 113
effective length of query: 550
effective length of database: 23,525,822
effective search space: 12939202100
effective search space used: 12939202100
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)