ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0918 good K KOG2587 Transcription RNA polymerase III (C) subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0918 323649 321679 -657
(657 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR190c [K] KOG2587 RNA polymerase III (C) subunit 633 0.0
SPAPB1E7.03 [K] KOG2587 RNA polymerase III (C) subunit 127 7e-29
HsM13376890 [K] KOG2587 RNA polymerase III (C) subunit 57 7e-08
Hs21359969 [K] KOG2587 RNA polymerase III (C) subunit 57 7e-08
>YPR190c [K] KOG2587 RNA polymerase III (C) subunit
Length = 654
Score = 633 bits (1632), Expect = 0.0
Identities = 317/640 (49%), Positives = 453/640 (70%), Gaps = 10/640 (1%)
Query: 23 SAAEPSTSTSPEPI-DISSLEQRTLNPDSFLYSELARSHLGERASTVLSVLVNKGRLSTR 81
S E +PE + ISSLEQRTLNPD FLY EL ++HLGERA++V+ +LV GRLS R
Sbjct: 18 STVESEKLVTPEDVMTISSLEQRTLNPDLFLYKELVKAHLGERAASVIGMLVALGRLSVR 77
Query: 82 EIHSFIPELSLSSIKTVLVSLIQLRCVQYLEETSLSGRKTLYYYFNEEGLFLMLYAGDIS 141
E+ I + + S+KT LVSL QLRCV+YL+ET++SG+KT YYY+NEEG+ ++LY+G I
Sbjct: 78 ELVEKIDGMDVDSVKTTLVSLTQLRCVKYLQETAISGKKTTYYYYNEEGIHILLYSGLII 137
Query: 142 DRIVQYFNQDEEQHLVNIAQQIIHNVLALGSLTVKDYLASESNSNDTDIFNIHQAFVRLA 201
D I+ ++E+ + +I+ NV++LGSLTV+DYL+S ++ D+ + I FV+L
Sbjct: 138 DEIITQMRVNDEEEHKQLVAEIVQNVISLGSLTVEDYLSSVTS--DSMKYTISSLFVQLC 195
Query: 202 DLEFLVPLQGIHYTPIVDLWNMLYLREYKKLPKNTTQSDLKKRNEAKAKAKLEFNRIVSS 261
++ +L+ + +HYTPI DLW LY + YK +P+N+ SDLKKR++AK AK +F +I++
Sbjct: 196 EMGYLIQISKLHYTPIEDLWQFLYEKHYKNIPRNSPLSDLKKRSQAKMNAKTDFAKIINK 255
Query: 262 PSQDSNGKIFLTDSGTGFKKVNESVSLTFNLERYLKSRRSNQLVQFAKSRIGTTSSKIYA 321
P++ S +I D T + V +VSLT NL+R++K RRS QL+ AK+R+G+ ++++Y
Sbjct: 256 PNELS--QILTVDPKTSLRIVKPTVSLTINLDRFMKGRRSKQLINLAKTRVGSVTAQVYK 313
Query: 322 VALSMTEQHSNGLSHPLSKTGLFQDLDERTSLEEDLKLDEENVKGVSFTALDVARRLPSN 381
+AL +TEQ S + PL++TGL QDL+E S +++ +L EE G++F A+D+AR LP+
Sbjct: 314 IALRLTEQKSPKIRDPLTQTGLLQDLEEAKSFQDEAELVEEKTPGLTFNAIDLARHLPAE 373
Query: 382 LDLRGTLVHSNQSLKRKQKHNQSPPQF-EKRIKTEDGFVVPPLPTVMXXXXXXXXXXXXX 440
LDLRG+L+ S +K+ + + K++KTEDGFV+P LP +
Sbjct: 374 LDLRGSLLSRKPSDNKKRSGSNAAASLPSKKLKTEDGFVIPALPAAVSKSLQESGDTQEE 433
Query: 441 XXXX----XXXXXPRSVSLVNGHLRLLLTANIPFIKESKPGQFFVPYSSLIPILKSSTYD 496
P S SL+N HL++L ++N PF+ E+KPG ++VPYS L+P+LKSS Y+
Sbjct: 434 DEEEEDLDADTEDPHSASLINSHLKILASSNFPFLNETKPGVYYVPYSKLMPVLKSSVYE 493
Query: 497 SIIASTLGPSSHRVLRCIRDNGLCTERTITTTSLMREKDVRTVIGTLVKYNAIEIQEVPR 556
+IASTLGPS+ R+ RCIRDN L +E+ I +T+LM+EKD+R+ + +L++YN++EIQEVPR
Sbjct: 494 YVIASTLGPSAMRLSRCIRDNKLVSEKIINSTALMKEKDIRSTLASLIRYNSVEIQEVPR 553
Query: 557 TVDRAASRAVFLFRIKEKHAFNTMKLNLTWNLARLISKLETLKEENATLLKKANRDDVKG 616
T DR+ASRAVFLFR KE H++N M+ NL WN+A L+ K E LK+EN+TLLKKANRDDVKG
Sbjct: 554 TADRSASRAVFLFRCKETHSYNFMRQNLEWNMANLLFKKEKLKQENSTLLKKANRDDVKG 613
Query: 617 REMELLLASEINQLKVVNDRELNGLVRRHRLLSLWEVFKL 656
RE ELLL SE+NQLK+VN+RELN R RLLSLWEVF++
Sbjct: 614 RENELLLPSELNQLKMVNERELNVFARLSRLLSLWEVFQM 653
>SPAPB1E7.03 [K] KOG2587 RNA polymerase III (C) subunit
Length = 591
Score = 127 bits (318), Expect = 7e-29
Identities = 140/634 (22%), Positives = 256/634 (40%), Gaps = 91/634 (14%)
Query: 56 LARSHLGERASTVLSVLVNKGRLSTREIHSFIPELSLSSIKTVLVSLIQLRCVQYLEETS 115
L G+ S V S L+ GRL+ + L I+ LVSL+Q V Y+
Sbjct: 12 LVEEFFGDCCSAVASALLRHGRLTIPMLQKRT-SLPGPKIRQALVSLMQHHMVLYVTVIE 70
Query: 116 LSGRKTLYYYFNEEGLFLMLYAGDISDRIVQYFNQDEEQHLVNIAQQIIHNVLALGSLTV 175
+ R+ YY + ++ +L G I Q NQ+ + ++ Q VL + +
Sbjct: 71 -NVREVTYYETQWKEIYNILRKGKDVYLISQKLNQEAASVVKYLSTQGRARVLEVFNAFD 129
Query: 176 KDYLASESNSNDTDIFNIHQAFVRLADLEFLVPLQGIHYTPIVDLWNMLYLREYKKLPKN 235
K S+ S + + L +FL+ +Q H P+ D L ++ + K+
Sbjct: 130 KKVDGSDEESR-----MMQKNLTELIYQKFLLVVQPRHLIPVGDQEMQLRIKHLDRR-KS 183
Query: 236 TTQSDLKKRNEAKAKAKLEF-----------------------------NRIVSSPSQDS 266
S++KK E LE R V S S
Sbjct: 184 ENVSEIKKNREVDDSVALEMLELRAADMSELQGLTRKPKESIPHPTKRRKRAVGSAPSVS 243
Query: 267 NGKIFLTDSGTGFKKVNESVSLTFNLERYLKSRRSNQLVQFAKSRIGTTSSKIYAVALSM 326
+ D + S + N + ++ +L + + RIG ++S +Y+ LSM
Sbjct: 244 TDLNNILDDDNSILVPDLSAHVRINSGKLSVLSKNARLTHWVERRIGKSTSLVYSHVLSM 303
Query: 327 TEQHSNGLSHPLSKTGLFQDLDERTSLEEDLKLDEENVKGVSFTALDVARRLPSNLDLRG 386
E +S+ ++ +F + T +++ R P+++D+
Sbjct: 304 LEPRLFSISN---QSPVF-----------------------TLTTMELTRNFPNDIDVES 337
Query: 387 TLVHSNQSLKRKQKHNQSPPQFEK--RIKTEDGFVVPPLPTVMXXXXXXXXXXXXXXXXX 444
++V S+ + + + + ED +
Sbjct: 338 SIVDKQYSVNSASNELRVMEKLNELDELAEEDNY-----------------------EES 374
Query: 445 XXXXXPRSVSLVNGHLRLLLTANIPFIKE---SKPGQFFVPYSSLIPILKSSTYDSIIAS 501
R ++ HL LL ++ FI + G++ V ++ L +L++ Y++ I
Sbjct: 375 VDENANRKSKVLAQHLELLADCSLKFISKIGNRGMGEWAVNFTHLTDMLRAIEYENFIEQ 434
Query: 502 TLGPSSHRVLRCIRDNGLCTERTITTTSLMREKDVRTVIGTLVKYNAIEIQEVPRTVDRA 561
G + R+LR I+D G E+ + +L+R++D+RTV+ + + A+E+QEVPR+ DRA
Sbjct: 435 KFGERAIRLLRIIKDKGKIEEKQLANIALLRQRDLRTVLQAMAEIGALELQEVPRSSDRA 494
Query: 562 ASRAVFLFRIKEKHAFNTMKLNLTWNLARLISKLETLKEENATLLKKANRDDVKGREMEL 621
S+ FL+ + A++ + L +ARL +L + + A L++KA R D+KG E +
Sbjct: 495 PSKTFFLWFHRPDRAYSLLLDELYHVIARLYMRLRDARAQRAQLIEKAERIDIKGNEEQY 554
Query: 622 LLASEINQLKVVNDRELNGLVRRHRLLSLWEVFK 655
L E +LK + E L++ RL + VF+
Sbjct: 555 LQKFEQAELKKLYSYEEKLLLQASRLDDMVLVFR 588
>HsM13376890 [K] KOG2587 RNA polymerase III (C) subunit
Length = 534
Score = 57.4 bits (137), Expect = 7e-08
Identities = 37/178 (20%), Positives = 83/178 (45%), Gaps = 3/178 (1%)
Query: 452 SVSLVNGHLRLLLTANIPFIKESKP---GQFFVPYSSLIPILKSSTYDSIIASTLGPSSH 508
S +++ +L LL + F+ +S G + + + L ++T +S++ G
Sbjct: 304 SKQVLDQYLTLLADDPLEFVGKSGDSGGGMYVINLHKALASLATATLESVVQERFGSRCA 363
Query: 509 RVLRCIRDNGLCTERTITTTSLMREKDVRTVIGTLVKYNAIEIQEVPRTVDRAASRAVFL 568
R+ R + ++ + +++ K+ + ++ ++ N + +QE+P+T D A SR +L
Sbjct: 364 RIFRLVLQKKHIEQKQVEDFAMIPAKEAKDMLYKMLSENFMSLQEIPKTPDHAPSRTFYL 423
Query: 569 FRIKEKHAFNTMKLNLTWNLARLISKLETLKEENATLLKKANRDDVKGREMELLLASE 626
+ + A + ++A LI + + +EN LL+K+ R + M+ A E
Sbjct: 424 YTVNILSAARMLLHRCYKSIANLIERRQFETKENKRLLEKSQRVEAIIASMQATGAEE 481
>Hs21359969 [K] KOG2587 RNA polymerase III (C) subunit
Length = 534
Score = 57.4 bits (137), Expect = 7e-08
Identities = 37/178 (20%), Positives = 83/178 (45%), Gaps = 3/178 (1%)
Query: 452 SVSLVNGHLRLLLTANIPFIKESKP---GQFFVPYSSLIPILKSSTYDSIIASTLGPSSH 508
S +++ +L LL + F+ +S G + + + L ++T +S++ G
Sbjct: 304 SKQVLDQYLTLLADDPLEFVGKSGDSGGGMYVINLHKALASLATATLESVVQERFGSRCA 363
Query: 509 RVLRCIRDNGLCTERTITTTSLMREKDVRTVIGTLVKYNAIEIQEVPRTVDRAASRAVFL 568
R+ R + ++ + +++ K+ + ++ ++ N + +QE+P+T D A SR +L
Sbjct: 364 RIFRLVLQKKHIEQKQVEDFAMIPAKEAKDMLYKMLSENFMSLQEIPKTPDHAPSRTFYL 423
Query: 569 FRIKEKHAFNTMKLNLTWNLARLISKLETLKEENATLLKKANRDDVKGREMELLLASE 626
+ + A + ++A LI + + +EN LL+K+ R + M+ A E
Sbjct: 424 YTVNILSAARMLLHRCYKSIANLIERRQFETKENKRLLEKSQRVEAIIASMQATGAEE 481
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,910,585
Number of Sequences: 60738
Number of extensions: 1412338
Number of successful extensions: 5106
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5092
Number of HSP's gapped (non-prelim): 8
length of query: 657
length of database: 30,389,216
effective HSP length: 113
effective length of query: 544
effective length of database: 23,525,822
effective search space: 12798047168
effective search space used: 12798047168
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)