ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII0935 check: MH RT KOG0598 General function prediction only Ribosomal protein S6 kinase and related proteins
r_klactII0935 check: MH RT KOG0598 Signal transduction mechanisms Ribosomal protein S6 kinase and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII0935 329075 326874 -734
(734 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 909 0.0
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 549 e-156
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 470 e-132
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 360 4e-99
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 332 1e-90
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 331 3e-90
7300106 [T] KOG0690 Serine/threonine protein kinase 303 5e-82
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 303 8e-82
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 299 9e-81
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 297 3e-80
CE15612 [T] KOG0690 Serine/threonine protein kinase 294 4e-79
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 291 2e-78
CE05274 [T] KOG0690 Serine/threonine protein kinase 290 4e-78
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 288 2e-77
CE18646 [T] KOG0690 Serine/threonine protein kinase 287 5e-77
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 285 1e-76
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 284 3e-76
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 284 4e-76
CE29298 [T] KOG0690 Serine/threonine protein kinase 281 3e-75
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 281 3e-75
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 280 7e-75
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 278 3e-74
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 278 3e-74
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 276 8e-74
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 274 3e-73
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 272 1e-72
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 271 3e-72
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 270 4e-72
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 265 1e-70
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 264 3e-70
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 263 9e-70
7295638 [T] KOG0603 Ribosomal protein S6 kinase 263 9e-70
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 262 1e-69
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 262 2e-69
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 262 2e-69
7303111 [T] KOG0695 Serine/threonine protein kinase 262 2e-69
7301734 [T] KOG0694 Serine/threonine protein kinase 262 2e-69
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 261 4e-69
7302860 [T] KOG0696 Serine/threonine protein kinase 260 5e-69
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 259 8e-69
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 259 1e-68
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 259 1e-68
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 259 1e-68
CE29092 [T] KOG0694 Serine/threonine protein kinase 258 3e-68
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 257 4e-68
7294770 [T] KOG0603 Ribosomal protein S6 kinase 257 5e-68
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 256 9e-68
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 256 1e-67
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 254 3e-67
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 250 5e-66
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 249 1e-65
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 248 2e-65
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 246 9e-65
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 246 1e-64
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 246 1e-64
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 246 1e-64
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 244 3e-64
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 244 4e-64
YBL105c [T] KOG0694 Serine/threonine protein kinase 243 8e-64
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 242 2e-63
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 241 2e-63
CE02586 [T] KOG0696 Serine/threonine protein kinase 241 2e-63
CE17354 [T] KOG0694 Serine/threonine protein kinase 241 3e-63
CE17353 [T] KOG0694 Serine/threonine protein kinase 241 3e-63
7302861 [T] KOG0696 Serine/threonine protein kinase 241 4e-63
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 240 5e-63
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 239 8e-63
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 239 1e-62
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 239 1e-62
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 238 2e-62
CE02604 [T] KOG0695 Serine/threonine protein kinase 237 5e-62
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 233 6e-61
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 233 8e-61
7303915 [T] KOG0694 Serine/threonine protein kinase 233 8e-61
7303914 [T] KOG0694 Serine/threonine protein kinase 233 8e-61
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 231 2e-60
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 229 1e-59
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 227 4e-59
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 221 2e-57
CE18699 [T] KOG0694 Serine/threonine protein kinase 221 3e-57
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 218 3e-56
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 216 1e-55
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 216 1e-55
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 215 2e-55
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 214 4e-55
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 214 4e-55
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 212 1e-54
CE02074 [T] KOG0986 G protein-coupled receptor kinase 212 1e-54
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 208 3e-53
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 208 3e-53
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 207 6e-53
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 207 6e-53
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 206 8e-53
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 205 2e-52
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 203 7e-52
7293735 [R] KOG0605 NDR and related serine/threonine kinases 203 7e-52
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 203 9e-52
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 202 1e-51
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 201 3e-51
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 201 3e-51
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 201 3e-51
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 201 3e-51
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 199 1e-50
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 199 1e-50
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 199 2e-50
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 198 2e-50
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 198 2e-50
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 198 3e-50
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 197 4e-50
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 197 6e-50
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 197 6e-50
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 196 8e-50
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 196 8e-50
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 196 1e-49
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 195 2e-49
CE03979 [T] KOG0614 cGMP-dependent protein kinase 195 2e-49
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 194 5e-49
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 194 5e-49
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 193 7e-49
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 193 9e-49
CE19898 [T] KOG0614 cGMP-dependent protein kinase 191 4e-48
CE19897 [T] KOG0614 cGMP-dependent protein kinase 191 4e-48
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 190 6e-48
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 189 1e-47
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 189 1e-47
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 189 1e-47
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 188 2e-47
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 188 3e-47
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 187 4e-47
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 186 8e-47
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 186 1e-46
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 184 3e-46
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 184 3e-46
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 184 3e-46
7296166 [T] KOG0614 cGMP-dependent protein kinase 184 4e-46
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 184 4e-46
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 182 1e-45
CE01554 [T] KOG0986 G protein-coupled receptor kinase 182 1e-45
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 182 2e-45
7297611 [T] KOG0614 cGMP-dependent protein kinase 181 4e-45
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 178 2e-44
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 176 1e-43
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 176 1e-43
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 174 4e-43
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 174 6e-43
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 174 6e-43
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 173 7e-43
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 173 7e-43
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 170 8e-42
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 168 2e-41
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 167 4e-41
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 165 2e-40
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 164 3e-40
At2g30360 [T] KOG0583 Serine/threonine protein kinase 164 5e-40
7299536 [D] KOG0580 Serine/threonine protein kinase 160 7e-39
7302050 [T] KOG0986 G protein-coupled receptor kinase 160 8e-39
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 157 4e-38
At4g18700 [T] KOG0583 Serine/threonine protein kinase 157 4e-38
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 157 4e-38
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 157 6e-38
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 156 9e-38
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 155 3e-37
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 154 5e-37
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 154 5e-37
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 153 8e-37
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 153 8e-37
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 152 1e-36
At5g45810 [T] KOG0583 Serine/threonine protein kinase 152 2e-36
At2g45490 [D] KOG0580 Serine/threonine protein kinase 152 2e-36
YPL209c [D] KOG0580 Serine/threonine protein kinase 151 3e-36
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 151 3e-36
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 151 4e-36
CE21025 [D] KOG0580 Serine/threonine protein kinase 150 5e-36
At2g26980 [T] KOG0583 Serine/threonine protein kinase 150 5e-36
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 150 7e-36
7297776 [D] KOG0580 Serine/threonine protein kinase 150 7e-36
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 150 9e-36
At5g25110 [T] KOG0583 Serine/threonine protein kinase 150 9e-36
At3g01090 [T] KOG0583 Serine/threonine protein kinase 149 1e-35
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 148 3e-35
At1g29230 [T] KOG0583 Serine/threonine protein kinase 148 3e-35
At2g25880 [D] KOG0580 Serine/threonine protein kinase 148 3e-35
At4g30960 [T] KOG0583 Serine/threonine protein kinase 147 4e-35
At5g35410 [T] KOG0583 Serine/threonine protein kinase 147 6e-35
At5g10930 [T] KOG0583 Serine/threonine protein kinase 147 6e-35
At4g32830 [D] KOG0580 Serine/threonine protein kinase 147 6e-35
At5g01810 [T] KOG0583 Serine/threonine protein kinase 147 7e-35
At2g34180 [T] KOG0583 Serine/threonine protein kinase 146 1e-34
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 146 1e-34
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 145 2e-34
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 145 3e-34
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 145 3e-34
At1g30270 [T] KOG0583 Serine/threonine protein kinase 144 4e-34
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 144 6e-34
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 144 6e-34
CE24761 [D] KOG0580 Serine/threonine protein kinase 142 2e-33
At5g45820 [T] KOG0583 Serine/threonine protein kinase 142 2e-33
At4g24400 [T] KOG0583 Serine/threonine protein kinase 142 2e-33
At2g25090 [T] KOG0583 Serine/threonine protein kinase 142 2e-33
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 142 2e-33
At5g58380 [T] KOG0583 Serine/threonine protein kinase 141 4e-33
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 140 5e-33
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 7e-33
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 139 1e-32
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 139 2e-32
At5g01820 [T] KOG0583 Serine/threonine protein kinase 139 2e-32
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 138 3e-32
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 138 3e-32
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 138 3e-32
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 137 5e-32
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 137 5e-32
At4g14580 [T] KOG0583 Serine/threonine protein kinase 137 6e-32
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 137 6e-32
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 137 8e-32
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 136 1e-31
CE29300 [T] KOG0694 Serine/threonine protein kinase 136 1e-31
CE29299 [T] KOG0694 Serine/threonine protein kinase 136 1e-31
At5g39440 [T] KOG0583 Serine/threonine protein kinase 136 1e-31
At2g38490 [T] KOG0583 Serine/threonine protein kinase 136 1e-31
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 135 2e-31
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 135 2e-31
CE00847 [T] KOG0583 Serine/threonine protein kinase 135 3e-31
CE27768 [R] KOG0586 Serine/threonine protein kinase 134 4e-31
CE23838 [R] KOG0586 Serine/threonine protein kinase 134 4e-31
At5g07070 [T] KOG0583 Serine/threonine protein kinase 134 4e-31
At1g01140 [T] KOG0583 Serine/threonine protein kinase 134 4e-31
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 134 5e-31
At3g29160 [T] KOG0583 Serine/threonine protein kinase 134 5e-31
At3g23000 [T] KOG0583 Serine/threonine protein kinase 134 5e-31
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 134 7e-31
7299437 [R] KOG0586 Serine/threonine protein kinase 134 7e-31
7290150 [T] KOG0583 Serine/threonine protein kinase 133 9e-31
YDR477w [T] KOG0583 Serine/threonine protein kinase 132 1e-30
At1g16440 [R] KOG0610 Putative serine/threonine protein kinase 132 1e-30
7290249 [R] KOG0586 Serine/threonine protein kinase 132 1e-30
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 132 2e-30
At5g63650 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
7294217 [D] KOG0588 Serine/threonine protein kinase 132 2e-30
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 132 2e-30
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 131 3e-30
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 131 3e-30
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 131 3e-30
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 131 4e-30
CE28479 [T] KOG0583 Serine/threonine protein kinase 131 4e-30
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 131 4e-30
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 130 6e-30
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 130 6e-30
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 130 6e-30
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 130 6e-30
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 130 7e-30
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 130 7e-30
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 7e-30
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 130 9e-30
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 130 9e-30
At5g66880 [T] KOG0583 Serine/threonine protein kinase 130 9e-30
YLR096w [T] KOG0583 Serine/threonine protein kinase 129 1e-29
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
CE28643 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 129 2e-29
At4g33950 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
7299438 [R] KOG0586 Serine/threonine protein kinase 129 2e-29
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 129 2e-29
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 129 2e-29
At5g08590 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
ECU10g0570 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 128 3e-29
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 128 3e-29
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 128 4e-29
Hs21450709 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 128 4e-29
At4g40010 [T] KOG0583 Serine/threonine protein kinase 128 4e-29
At2g23030 [T] KOG0583 Serine/threonine protein kinase 128 4e-29
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 5e-29
CE07458 [T] KOG0583 Serine/threonine protein kinase 127 6e-29
At3g17510 [T] KOG0583 Serine/threonine protein kinase 127 6e-29
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 126 1e-28
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 126 1e-28
YPL150w [T] KOG0583 Serine/threonine protein kinase 126 1e-28
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
Hs22043324 [T] KOG0603 Ribosomal protein S6 kinase 125 2e-28
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 125 2e-28
At1g78290 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
7302464 [R] KOG0586 Serine/threonine protein kinase 125 2e-28
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 125 3e-28
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 125 3e-28
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 4e-28
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 124 5e-28
CE16081 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
At3g50500 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
At1g60940 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
At1g10940 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 124 5e-28
YDR122w [T] KOG0583 Serine/threonine protein kinase 124 7e-28
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 124 7e-28
At5g57630 [T] KOG0583 Serine/threonine protein kinase 124 7e-28
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 123 9e-28
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 123 9e-28
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 123 9e-28
YKL101w [D] KOG0588 Serine/threonine protein kinase 123 1e-27
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 123 1e-27
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 123 1e-27
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 2e-27
At3g20860 [R] KOG0589 Serine/threonine protein kinase 122 2e-27
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 122 3e-27
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 122 3e-27
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 122 3e-27
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 3e-27
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 121 3e-27
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 121 3e-27
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 121 3e-27
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 3e-27
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 3e-27
At1g79250 [R] KOG0610 Putative serine/threonine protein kinase 121 3e-27
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 121 4e-27
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 4e-27
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 120 6e-27
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 120 6e-27
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 6e-27
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 6e-27
Hs22065405 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 120 7e-27
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 120 1e-26
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 1e-26
7302570 [R] KOG0586 Serine/threonine protein kinase 120 1e-26
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 120 1e-26
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 1e-26
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 1e-26
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 119 2e-26
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 2e-26
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 2e-26
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 2e-26
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 119 2e-26
YDR507c [D] KOG0588 Serine/threonine protein kinase 119 2e-26
CE28218 [D] KOG0588 Serine/threonine protein kinase 119 2e-26
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 118 3e-26
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 118 3e-26
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 118 4e-26
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 4e-26
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 117 5e-26
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 117 5e-26
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 117 6e-26
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 117 6e-26
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 117 6e-26
At2g20040 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 117 6e-26
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 117 8e-26
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 117 8e-26
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 117 8e-26
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 116 1e-25
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 116 1e-25
At1g54510 [R] KOG0589 Serine/threonine protein kinase 116 1e-25
7303211 [T] KOG4717 Serine/threonine protein kinase 116 1e-25
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 116 1e-25
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 116 1e-25
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 116 1e-25
CE17284 [T] KOG0583 Serine/threonine protein kinase 116 1e-25
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 116 1e-25
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 116 1e-25
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 115 2e-25
At3g15220 [T] KOG0201 Serine/threonine protein kinase 115 2e-25
At1g48260 [T] KOG0583 Serine/threonine protein kinase 115 2e-25
Hs22053778_2 [T] KOG0986 G protein-coupled receptor kinase 115 2e-25
YHR102w [T] KOG0201 Serine/threonine protein kinase 115 2e-25
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 115 2e-25
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 115 2e-25
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 115 2e-25
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 2e-25
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 3e-25
YOR233w [T] KOG0583 Serine/threonine protein kinase 114 4e-25
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 114 4e-25
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 4e-25
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 4e-25
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 114 4e-25
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 114 5e-25
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 114 5e-25
At3g04810 [R] KOG0589 Serine/threonine protein kinase 114 5e-25
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 114 5e-25
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 114 7e-25
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 113 9e-25
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 113 9e-25
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 113 9e-25
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 9e-25
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 113 9e-25
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 113 1e-24
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 1e-24
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 1e-24
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
At5g28290 [R] KOG0589 Serine/threonine protein kinase 112 2e-24
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 112 2e-24
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 111 3e-24
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 111 3e-24
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 111 3e-24
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 111 5e-24
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 111 5e-24
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 111 5e-24
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 111 5e-24
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 6e-24
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 6e-24
YDR523c [T] KOG0201 Serine/threonine protein kinase 110 8e-24
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 110 8e-24
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 110 8e-24
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 110 8e-24
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 8e-24
7290147 [T] KOG0583 Serine/threonine protein kinase 110 8e-24
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 110 8e-24
CE17343 [T] KOG0583 Serine/threonine protein kinase 109 1e-23
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 109 1e-23
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 1e-23
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 109 1e-23
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 109 1e-23
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 109 2e-23
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 109 2e-23
CE18366 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 109 2e-23
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 108 2e-23
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 108 2e-23
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 108 2e-23
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 108 2e-23
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 108 3e-23
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 108 3e-23
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 108 3e-23
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 108 3e-23
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 108 4e-23
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 108 4e-23
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 108 4e-23
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 108 4e-23
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 108 4e-23
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 4e-23
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 4e-23
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 107 5e-23
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 107 5e-23
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 107 5e-23
CE18454 [T] KOG4717 Serine/threonine protein kinase 107 5e-23
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 107 5e-23
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 5e-23
7291043 [T] KOG0660 Mitogen-activated protein kinase 107 5e-23
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 107 7e-23
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 107 7e-23
YCL024w [T] KOG0583 Serine/threonine protein kinase 107 9e-23
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 107 9e-23
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 107 9e-23
At5g55910 [R] KOG0610 Putative serine/threonine protein kinase 107 9e-23
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 9e-23
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 9e-23
At1g53165 [T] KOG0201 Serine/threonine protein kinase 107 9e-23
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 107 9e-23
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 106 1e-22
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 106 1e-22
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 106 1e-22
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 106 1e-22
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 105 2e-22
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 105 2e-22
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 105 2e-22
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 105 2e-22
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 105 2e-22
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 2e-22
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 105 2e-22
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 105 2e-22
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 105 2e-22
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 105 2e-22
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 105 3e-22
At4g26610 [R] KOG0610 Putative serine/threonine protein kinase 105 3e-22
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 105 3e-22
7300224 [T] KOG0201 Serine/threonine protein kinase 105 3e-22
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 104 4e-22
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 104 4e-22
Hs14759411 [TR] KOG0606 Microtubule-associated serine/threonine ... 104 4e-22
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 104 4e-22
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 104 4e-22
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 104 4e-22
CE21239 [T] KOG0583 Serine/threonine protein kinase 104 6e-22
YPL141c [T] KOG0583 Serine/threonine protein kinase 103 7e-22
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 103 7e-22
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 103 7e-22
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 103 7e-22
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 103 9e-22
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 103 9e-22
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 103 9e-22
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 103 9e-22
At5g47750 [R] KOG0610 Putative serine/threonine protein kinase 103 9e-22
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 9e-22
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 103 1e-21
At3g52890 [R] KOG0610 Putative serine/threonine protein kinase 103 1e-21
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 103 1e-21
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 103 1e-21
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 103 1e-21
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 102 2e-21
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 909 bits (2348), Expect = 0.0
Identities = 490/761 (64%), Positives = 546/761 (71%), Gaps = 69/761 (9%)
Query: 39 TATPTTALSEHSYAMGTTGL-NQNRQQQENILDHMKASMDSNIXXXXXXXXXXXXXXRAP 97
TATPTTA+S+ YAMGTTG+ ++N Q +++ +S+++N A
Sbjct: 68 TATPTTAISQDLYAMGTTGITSENALFQMKSMNNGISSVNNNNSNTPTIITTSQEETNAG 127
Query: 98 QY--------AQSSDAAQPSMAAAPEIXXXXXXXXXXXXXXXXXXX----XQLPRGKLRI 145
Q+S+ S ++ + +PRGKL +
Sbjct: 128 NVHGDTGGNSLQNSEDDNFSSSSTTKCLLSSTSSLSINQREAAAAAYGPDTDIPRGKLEV 187
Query: 146 VIAEALNLSIRSPSASQPYVVCTFESSEFISNGPESL----------------------- 182
I EA +L RS SQPYVVCTFESSEFISNGPESL
Sbjct: 188 TIIEARDLVTRSKD-SQPYVVCTFESSEFISNGPESLGAINNNNNNNNNNQHNQNQHINN 246
Query: 183 --DNKYPSISAANSNNQ--WSKGLL-NTNEKLKR-PLYTRQSSSQLDKLGN--------- 227
+N P ++ + NN W+ L + E LK+ PLYT +SSSQLD+L +
Sbjct: 247 NNENTNPDAASQHHNNNSGWNGSQLPSIKEHLKKKPLYTHRSSSQLDQLNSCSSVTDPSK 306
Query: 228 NQLNLKRGSIN--------PVWEHEATFDVLGTHSELDISIYDAAQDDMFLGQVRLHPNM 279
N GS N P+W H+ TFDVLG+HSELDIS+YDAA D MFLGQVRL+P +
Sbjct: 307 RSSNSSSGSSNGPKNDSSHPIWHHKTTFDVLGSHSELDISVYDAAHDHMFLGQVRLYPMI 366
Query: 280 NAVTPGVHSEWHKLKSRALGEHVTGDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQV 339
+ + +WH LK R + E V+GDILI W Y TKKR YGPQDFEVLRLLGKGTFGQV
Sbjct: 367 HNLAHASQHQWHSLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQV 426
Query: 340 YQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPT 399
YQV+KKDT RIYAMKVLSKKVIVKKNEIAHTIGERNILV TASKSSPFIVGLKFSFQTPT
Sbjct: 427 YQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPT 486
Query: 400 DLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILL 459
DLYLVTD+MSGGELFWHLQKEGRF+EDRAKFYIAELVLALE+LHDNDIVYRDLKPENILL
Sbjct: 487 DLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILL 546
Query: 460 DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMC 519
DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELL+DETGYTKMVDFWSLGVLIFEMC
Sbjct: 547 DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMC 606
Query: 520 CGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELR 579
CGWSPFFA +NQKMYQKIAFGKVKFPRDVLS EGRSFVKGLLNRNPKHRLGAIDDGRELR
Sbjct: 607 CGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELR 666
Query: 580 AHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTSTSFMNK-QP-IAATPLS 637
AHPFF DIDWEA++QKKIPPPFKPHL+SETDTSNFDPEFT STS+MNK QP + ATPLS
Sbjct: 667 AHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLS 726
Query: 638 PAMQAKFVGFTFVDESAIDEHYNNAYNNRKFLQNSYFMEPGSFIPGNPNLPP----XXXX 693
PAMQAKF GFTFVDESAIDEH N NNRKFLQNSYFMEPGSFIPGNPNLPP
Sbjct: 727 PAMQAKFAGFTFVDESAIDEHVN---NNRKFLQNSYFMEPGSFIPGNPNLPPDEDVIDDD 783
Query: 694 XXXXXXXXXRLAAVKGSGGISVDYDGDHHMDDEFVNGRFEI 734
+ +D+DGD HMDDEFV+GRFEI
Sbjct: 784 GDEDINDGFNQEKNMNNSHSQMDFDGDQHMDDEFVSGRFEI 824
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 549 bits (1415), Expect = e-156
Identities = 291/529 (55%), Positives = 370/529 (69%), Gaps = 31/529 (5%)
Query: 141 GKLRIVIAEALNLSIRSPSASQPYVVCTFESSEFISNGP-ESLDNKYPSISAANSNNQWS 199
G+L + + + +L+++S +A QPY V TFE ++ + P + +D P IS + N
Sbjct: 139 GRLYVRLHQGRDLNVKSVNA-QPYAVITFEKTQVMVPPPFKDIDGGIP-ISIPSKN---- 192
Query: 200 KGLLNTNEKLKRPLYTRQSSSQLDKLGNNQLNLKRGSINPVWEHEATFDVLGTHSELDIS 259
RPL S S L R P W+ E FDV S++ +S
Sbjct: 193 -----------RPLAGSASGSSSGLHSELMLADVRC---PHWDFETVFDVTKMKSQMVVS 238
Query: 260 IYDAAQDDMFLGQVRLHPNMNAVTPGVHSEWHKLKSRALGEHVTGDILIHWEYTSTKKRQ 319
+YD +DD FLG V++ P + V W+KL+ L + + G+I + Y + +
Sbjct: 239 VYDKYEDDKFLGSVKITPIF--LHEYVQEAWYKLEPLDLTKSLEGEIKVETIYEHIEHVR 296
Query: 320 YGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVR 379
YGP+DF LRL+GKGTFGQVY VRK DT RIYAMK +SKK+IV+K E+ HT+GERNILVR
Sbjct: 297 YGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVR 356
Query: 380 TASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLAL 439
T+ SPFIVGLKFSFQT +DLYL+TD+MSGGELFWHLQ EGRF E RAKFYIAELVLAL
Sbjct: 357 TSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLAL 416
Query: 440 EYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLM 497
E+LH +DI+YRDLKPENILLDA+G+IALCDFGLSKA+L TNTFCGTTEYLAPE+L+
Sbjct: 417 EHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLL 476
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
++ GYTK VDFWSLGVL+FEMCCGWSPF+A D Q+MY+ IAFGKV+FP+ VLS EGRSFV
Sbjct: 477 EDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSFV 536
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPE 617
+GLLNRNP HRLGA+ D EL+ HPFF DI+W+ + +KK+ PPFKP++ ++ D SNFD E
Sbjct: 537 RGLLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKVQPPFKPNVQNDLDVSNFDKE 596
Query: 618 FTQTSTSFMN-----KQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNN 661
FT T+ +N A+TPLS +Q +F GFTFV++S IDE + N
Sbjct: 597 FTNTNVKNINIVSNVDPANASTPLSNTIQDRFRGFTFVNKS-IDEQFQN 644
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 470 bits (1209), Expect = e-132
Identities = 259/529 (48%), Positives = 341/529 (63%), Gaps = 46/529 (8%)
Query: 153 LSIRSPSASQPYVVCTFESSEFISNGPESLDNKYPSI--SAANSNNQWSKGLLNTNEKLK 210
L++ +Q +VV F ++EF+S P ++ I S+ +S N + ++ +
Sbjct: 111 LAMECSRLNQLFVVVQFGTTEFVSP-PLKWESPGRDIGTSSRDSANVSRSSSMMSSHPIP 169
Query: 211 RPLYTRQSSSQLDKLGNNQLNLKRGSINPVWEHEATFDVLGTHSELDISIYDAAQDDMFL 270
P R SS NP+ FDV +D++IYD ++ F+
Sbjct: 170 TPAIQRTSSIP----------------NPLTPSYVVFDV-AKPVPIDVNIYDHGNNNEFV 212
Query: 271 GQVRLHPNMNAVTPGVHSEWHKL-----KSRALGEHVTGDILIHWEYTSTKKRQYGPQDF 325
G+ +HP+ N + ++ + S A V + ++ + + YGP DF
Sbjct: 213 GRTYIHPSYN------YGQFEQFCNSVEVSPAYNRMVDLRLSLNTVFQPLSQHSYGPDDF 266
Query: 326 EVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSS 385
L+L+GKGTFGQVY VRKKDT R+YAMKVLSKKVIV++ E+AHT+GER+ILV+T++ S
Sbjct: 267 VPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAADS 326
Query: 386 PFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDN 445
PFIV L+FSFQTP DLYLVTD+M+GGELFWHLQK RF E+RAKFYIAEL+LAL+ LH
Sbjct: 327 PFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALHKR 386
Query: 446 DIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLMDETGYT 503
IVYRDLKPENILLD G+IALCDFGLSKA+L T TFCGTT+YLAPE+++DE GY
Sbjct: 387 GIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDEAGYD 446
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
MVDFWSLGVL++EM CGWSPF+A + Q++Y+ I FGKV+FPR +LS E R +K LLNR
Sbjct: 447 MMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEARDLIKLLLNR 506
Query: 564 NPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ--- 620
NPKHRLGA D E+ HPFF+ IDW+ + K+I PPFKP + E D SNFD EFT
Sbjct: 507 NPKHRLGAHGDVEEVMKHPFFDGIDWKKLAAKEISPPFKPIVEGEIDVSNFDVEFTNKAI 566
Query: 621 ----TSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNN 665
+ST M+ + PLS +Q F GFT++D SA+DE + Y+N
Sbjct: 567 DRDFSSTDEMS----TSAPLSSTVQNGFKGFTYIDASAMDEAF--GYHN 609
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 360 bits (924), Expect = 4e-99
Identities = 198/430 (46%), Positives = 280/430 (65%), Gaps = 29/430 (6%)
Query: 238 NPVWEHEATFDVLGTHSELDISIY---------DAAQDDMFLGQVRLHPNMNAVTPGVHS 288
NP W+++ATFDV +S+L ++IY + +D FLG ++L P+ + +
Sbjct: 143 NPCWDYQATFDV-SRYSKLSLNIYLRSSSSRSRNGMGNDAFLGGIKLSPSF--IVNKLTD 199
Query: 289 EWHKLKSRALGEHVTGDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTM 348
EW L + G++ + Y + FE+L+++GKG+FG+V QVRK+DT
Sbjct: 200 EWVPLHGGS------GELRVQMLYKPNQSTPLTIDAFELLKVVGKGSFGKVMQVRKRDTS 253
Query: 349 RIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFM 408
RIYA+K + K IV ++E+ HT+ ER +L A ++PFIV LKFSFQ+P LYLV F+
Sbjct: 254 RIYALKTMKKAHIVSRSEVDHTLAERTVL---AQVNNPFIVPLKFSFQSPGKLYLVLAFV 310
Query: 409 SGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALC 468
+GGELF HLQ+EG F RAKFYIAEL++ALE LH+ +++YRDLKPENILLD G+IALC
Sbjct: 311 NGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNVIYRDLKPENILLDYTGHIALC 370
Query: 469 DFGLSKADL--KDRTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFF 526
DFGL K ++ DRTNTFCGT EYLAPELL+ GYTK+VD+W+LGVL++EM G PF+
Sbjct: 371 DFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGH-GYTKVVDWWTLGVLLYEMITGLPPFY 429
Query: 527 ASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFND 586
+ +MY+KI ++FP D + + + + GLL R P+ RLG+ +E++ HPFF+D
Sbjct: 430 DENINEMYRKILQDPLRFP-DNIDEKAKDLLSGLLTRAPEKRLGS-GGAQEIKNHPFFDD 487
Query: 587 IDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVG 646
IDW+ + KKI PPFKP + S DTSNFD EFT + +A + LS +Q +F
Sbjct: 488 IDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFT---SEIPMDSVVADSHLSETVQQRFAN 544
Query: 647 FTFVDESAID 656
+++ + ID
Sbjct: 545 WSYQRPTTID 554
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 332 bits (852), Expect = 1e-90
Identities = 175/359 (48%), Positives = 245/359 (67%), Gaps = 18/359 (5%)
Query: 304 GDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVK 363
G + I +Y +K + DF++L+++GKG+FG+V QVRKKDT +IYA+K L K IV
Sbjct: 323 GKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVS 382
Query: 364 KNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRF 423
K E+ HT+ ER +L R PFIV LKFSFQ+P LYLV F++GGELF+HLQ EGRF
Sbjct: 383 KCEVTHTLAERTVLARV---DCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRF 439
Query: 424 TEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRT 481
+ R++FYIAEL+ AL+ LH D++YRDLKPENILLD G+IALCDFGL K ++K D+T
Sbjct: 440 SLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKT 499
Query: 482 NTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK 541
+TFCGT EYLAPE+L+ + GYTK VD+W+LG+L++EM G P++ + MY+KI
Sbjct: 500 DTFCGTPEYLAPEILLGQ-GYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQP 558
Query: 542 VKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPF 601
+ FP D P + + GLL+R+P RLG ++ E+R HPFF DI W+ + K PP+
Sbjct: 559 LLFP-DGFDPAAKDLLIGLLSRDPSRRLG-VNGTDEIRNHPFFKDISWKKLLLKGYIPPY 616
Query: 602 KPHLISETDTSNFDPEFTQTSTSFMNKQPIAATP---LSPAMQAKFVGFTFVDESAIDE 657
KP + SE DT+NFD EFT+ ++PI + LS ++Q +F G+T++ + + +
Sbjct: 617 KPIVKSEIDTANFDQEFTK-------EKPIDSVVDEYLSASIQKQFGGWTYIGDEQLGD 668
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 331 bits (848), Expect = 3e-90
Identities = 175/352 (49%), Positives = 239/352 (67%), Gaps = 18/352 (5%)
Query: 304 GDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVK 363
G I I +Y ++ + DF++L+++GKG+FG+V QVRKKDT ++YA+K + K IV
Sbjct: 326 GKINISIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVS 385
Query: 364 KNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRF 423
K+E+ HT+ ER +L R PFIV LKFSFQ+P LY V F++GGELF+HLQKEGRF
Sbjct: 386 KSEVTHTLAERTVLARV---DCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRF 442
Query: 424 TEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRT 481
RA+FY AEL+ AL+ LH D+VYRDLKPENILLD G+IALCDFGL K ++K D+T
Sbjct: 443 DLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKT 502
Query: 482 NTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK 541
+TFCGT EYLAPELL+ GYTK VD+W+LGVL++EM G P++ D KMY+KI
Sbjct: 503 DTFCGTPEYLAPELLLG-LGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEP 561
Query: 542 VKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPF 601
+ FP D + + + GLL+R+P RLG + E+R HPFF+ + W+ + K PP+
Sbjct: 562 LVFP-DGFDRDAKDLLIGLLSRDPTRRLG-YNGADEIRNHPFFSQLSWKRLLMKGYIPPY 619
Query: 602 KPHLISETDTSNFDPEFTQTSTSFMNKQPIAATP---LSPAMQAKFVGFTFV 650
KP + + DTSNFD EFT+ ++PI + LS ++Q +F G+T+V
Sbjct: 620 KPAVSNSMDTSNFDEEFTR-------EKPIDSVVDEYLSESVQKQFGGWTYV 664
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 303 bits (777), Expect = 5e-82
Identities = 158/325 (48%), Positives = 218/325 (66%), Gaps = 14/325 (4%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
++FE L++LGKGTFG+V R+K T ++YA+K+L K+VI++K+E+AHT+ E +L T
Sbjct: 183 ENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKST-- 240
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
+ PF++ LK+SFQT L V +++GGELFWHL E FTEDR +FY AE++ AL YL
Sbjct: 241 -NHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYL 299
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLMDET 500
H I+YRDLK EN+LLD +G+I + DFGL K D+ T TFCGT EYLAPE+L D+
Sbjct: 300 HSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVL-DDN 358
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
Y + VD+W GV+++EM CG PF+ D+ ++ I +VKFPR++ + E ++ + GL
Sbjct: 359 DYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNI-TDEAKNLLAGL 417
Query: 561 LNRNPKHRL-GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFT 619
L ++PK RL G DD +E++AHPFF I+W + KKIPPPFKP + S+TDT FD EFT
Sbjct: 418 LAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFT 477
Query: 620 QTSTSFMNKQP------IAATPLSP 638
S P IA PL P
Sbjct: 478 GESVELTPPDPTGPLGSIAEEPLFP 502
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 303 bits (775), Expect = 8e-82
Identities = 153/302 (50%), Positives = 211/302 (69%), Gaps = 8/302 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF+ L+LLGKGTFG+V VR+K T R YAMK+L K+VI+ K+E+AHT+ E +L T
Sbjct: 151 DFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRH- 209
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+ LK++FQT L V ++ +GGELF+HL +E FTE+RA+FY AE+V ALEYLH
Sbjct: 210 --PFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLMDETG 501
D+VYRD+K EN++LD +G+I + DFGL K + D TFCGT EYLAPE+L ++
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVL-EDND 326
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y + VD+W LGV+++EM CG PF+ D++++++ I +++FPR LSPE +S + GLL
Sbjct: 327 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR-TLSPEAKSLLAGLL 385
Query: 562 NRNPKHRL-GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
++PK RL G D +E+ H FF I+W+ V QKK+ PPFKP + SE DT FD EFT
Sbjct: 386 KKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTA 445
Query: 621 TS 622
S
Sbjct: 446 QS 447
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 299 bits (766), Expect = 9e-81
Identities = 153/307 (49%), Positives = 214/307 (68%), Gaps = 9/307 (2%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
K + +FE L+LLGKGTFG+V V++K T R YAMK+L K+VIV K+E+AHT+ E +
Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L + PF+ LK+SFQT L V ++ +GGELF+HL +E F+EDRA+FY AE+V
Sbjct: 202 L---QNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258
Query: 437 LALEYLH-DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAP 493
AL+YLH + ++VYRDLK EN++LD +G+I + DFGL K +KD TFCGT EYLAP
Sbjct: 259 SALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAP 318
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
E+L ++ Y + VD+W LGV+++EM CG PF+ D++K+++ I +++FPR L PE
Sbjct: 319 EVL-EDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-TLGPEA 376
Query: 554 RSFVKGLLNRNPKHRL-GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
+S + GLL ++PK RL G +D +E+ H FF I W+ V +KK+ PPFKP + SETDT
Sbjct: 377 KSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTR 436
Query: 613 NFDPEFT 619
FD EFT
Sbjct: 437 YFDEEFT 443
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 297 bits (761), Expect = 3e-80
Identities = 153/315 (48%), Positives = 216/315 (68%), Gaps = 9/315 (2%)
Query: 313 TSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIG 372
++T ++ DF+ L+LLGKGTFG+V VR+K + + YAMK+L K+VI+ K+E+AHT+
Sbjct: 136 STTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLT 195
Query: 373 ERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYI 432
E +L T PF+ LK+SFQT L V ++++GGELF+HL +E F+EDR +FY
Sbjct: 196 ESRVLKNTRH---PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYG 252
Query: 433 AELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT--NTFCGTTEY 490
AE+V AL+YLH IVYRDLK EN++LD +G+I + DFGL K + D TFCGT EY
Sbjct: 253 AEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEY 312
Query: 491 LAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLS 550
LAPE+L ++ Y + VD+W LGV+++EM CG PF+ D++K+++ I +KFPR LS
Sbjct: 313 LAPEVL-EDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLS 370
Query: 551 PEGRSFVKGLLNRNPKHRL-GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET 609
+ +S + GLL ++P RL G DD +E+ H FF+ ++W+ V KK+ PPFKP + SET
Sbjct: 371 SDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSET 430
Query: 610 DTSNFDPEFT-QTST 623
DT FD EFT QT T
Sbjct: 431 DTRYFDEEFTAQTIT 445
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 294 bits (752), Expect = 4e-79
Identities = 159/350 (45%), Positives = 227/350 (64%), Gaps = 27/350 (7%)
Query: 314 STKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGE 373
+ K+ + +DF+ L++LGKGTFG+V ++K T ++YA+K+L K VI+ + E+AHT+ E
Sbjct: 182 AAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTE 241
Query: 374 RNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIA 433
+L R PF+ LK+SFQ L V F +GGELF H++K G F+E RA+FY A
Sbjct: 242 NRVLQRC---KHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGA 298
Query: 434 ELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYL 491
E+VLAL YLH DIVYRD+K EN+LLD +G+I + DFGL K ++ D+T+TFCGT EYL
Sbjct: 299 EIVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYL 358
Query: 492 APELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSP 551
APE+L D+ Y + VD+W +GV+++EM CG PF++ D+ K+++ I G ++FP LS
Sbjct: 359 APEVL-DDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFP-SKLSQ 416
Query: 552 EGRSFVKGLLNRNPKHRL-GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETD 610
E R+ + GLL ++P RL G +D E+ FF +DWEA +K+I PP+KP++ SETD
Sbjct: 417 EARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETD 476
Query: 611 TSNFDPEFTQTSTSFMNKQPIAATPLSPA-----------MQAKFVGFTF 649
TS FD EFT QP+ TP S + MQ+ F F+F
Sbjct: 477 TSYFDNEFT--------SQPVQLTPPSRSGALATVDEQEEMQSNFTQFSF 518
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 291 bits (746), Expect = 2e-78
Identities = 160/343 (46%), Positives = 225/343 (64%), Gaps = 16/343 (4%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVK-KNEIAHTIGERNI 376
GP+DF++L++LGKG +G+V+QVRK D +I+AMKVL K IV+ + + AHT ERNI
Sbjct: 79 GPEDFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNI 138
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L + SPFI L ++FQT LYL+ +++SGGELF HL++EG F E+ AKFY++E+V
Sbjct: 139 L---EAVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIV 195
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPE 494
++LE+LH I+YRDLKPENILLDA G++ L DFGL K +++ +T+TFCGT EY+APE
Sbjct: 196 VSLEHLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPE 255
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
+LM G+ K VD+WSLG L+F+M G PF A + +K KI G++ P LS E R
Sbjct: 256 ILM-RCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPA-YLSNEAR 313
Query: 555 SFVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSN 613
+K LL R+ RLGA + D E+++H FF DW V +++ PFKP++ ++ DTS
Sbjct: 314 DLIKKLLKRHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDEDTSL 373
Query: 614 FDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAID 656
FD FT+ + T S FVGFT+V S ++
Sbjct: 374 FDARFTKMTP----VDSPCETNFSLNGDNPFVGFTYVAPSVLE 412
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 290 bits (743), Expect = 4e-78
Identities = 158/355 (44%), Positives = 229/355 (64%), Gaps = 32/355 (9%)
Query: 314 STKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGE 373
+ K+ + +DF+ L++LGKGTFG+V ++K T ++YA+K+L K VI+ + E+AHT+ E
Sbjct: 182 AAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTE 241
Query: 374 RNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGR-----FTEDRA 428
+L R PF+ LK+SFQT L V +F GG+L++HL +E + F+E RA
Sbjct: 242 NRVLQRC---KHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRA 298
Query: 429 KFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCG 486
+FY +E+VLAL YLH N IVYRDLK EN+LLD +G+I + DFGL K ++ D+T+TFCG
Sbjct: 299 RFYGSEIVLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCG 358
Query: 487 TTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR 546
T EYLAPE+L D+ Y + VD+W +GV+++EM CG PF++ D+ K+++ I G ++FP
Sbjct: 359 TPEYLAPEVL-DDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFP- 416
Query: 547 DVLSPEGRSFVKGLLNRNPKHRL-GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHL 605
LS E R+ + GLL ++P RL G +D E+ FF +DWEA +K+I PP+KP++
Sbjct: 417 SKLSQEARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNV 476
Query: 606 ISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPA-----------MQAKFVGFTF 649
SETDTS FD EFT QP+ TP S + MQ+ F F+F
Sbjct: 477 QSETDTSYFDNEFT--------SQPVQLTPPSRSGALATVDEQEEMQSNFTQFSF 523
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 288 bits (737), Expect = 2e-77
Identities = 151/336 (44%), Positives = 213/336 (62%), Gaps = 12/336 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF+ L +GKG+FG+VYQVR K+T +IYAMK+LSK+ I KKNE+ H + ERN+L+
Sbjct: 93 DFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFKH 152
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V L FSFQ LY V D ++GGELF HLQ+E F+E R++FY AE+ AL YLH
Sbjct: 153 --PFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLH 210
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLMDETG 501
+ +I+YRDLKPEN+LLD G + L DFGL K D++ T+TFCGT EYLAPE+++ +
Sbjct: 211 EKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKP- 269
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y K VD+W LG +++EM G PF++ D+ +MY KI ++ ++ P + GLL
Sbjct: 270 YDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVP-CSELITGLL 328
Query: 562 NRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFT-- 619
++ RLG +D R++R HPFF +DW+ + +++ PF P + + DTSN EF
Sbjct: 329 QKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEI 388
Query: 620 QTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAI 655
Q S + Q +A T F FTFVD + +
Sbjct: 389 QIDPSSLAPQQLAVT----HRDHDFENFTFVDTNRV 420
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 287 bits (734), Expect = 5e-77
Identities = 152/360 (42%), Positives = 232/360 (64%), Gaps = 12/360 (3%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
+K DF+ L++LG+GTFG+V R+K + ++YA+K++ K+++V ++E+AHT+ E
Sbjct: 171 RKNTVTMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENR 230
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
+L PF+ LK+SFQ + V +F +GGELF HLQ+ F+E R +FY +E+
Sbjct: 231 VLYACVH---PFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEI 287
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAP 493
+LAL YLH +IVYRD+K EN+LLD +G+I + DFGL K ++K D+T+TFCGT EYLAP
Sbjct: 288 ILALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAP 347
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
E++ ++ Y + VD+W +GV+++EM CG PF A +N K+++ I +KFP + LSPE
Sbjct: 348 EVI-EDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFP-NRLSPEA 405
Query: 554 RSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
+ + GLL R P RLGA DD RE+ FF D+DWEA +K++ PPFKP+++SETDTS
Sbjct: 406 VTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTS 465
Query: 613 NFDPEFTQTS---TSFMNKQPIAATPLSPAMQAKFVGF-TFVDESAIDEHYNNAYNNRKF 668
FD EFT T + + +QA F+ F ++ +++ Y+ + K+
Sbjct: 466 FFDREFTSMPVQLTPPRRGEELPTVDEEEELQANFIQFASYYVSGSLERSYDTNRSADKY 525
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 285 bits (730), Expect = 1e-76
Identities = 148/339 (43%), Positives = 220/339 (64%), Gaps = 18/339 (5%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
P DF+ L+++GKG +G+V ++K YA+KVL KK I+KK E +H + ER++L++
Sbjct: 92 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 151
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
PF+VGL++SFQTP LY V D+++GGELF+HLQ+E RF E RA+FY AE+ A+ Y
Sbjct: 152 RH--PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGY 209
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELLMDE 499
LH +I+YRDLKPENILLD G++ L DFGL K + +D T+TFCGT EYLAPE+L E
Sbjct: 210 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 269
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFP--RDVLSPEGRSFV 557
Y + VD+W LG +++EM G PF++ D +MY+ I ++ P R V + + +
Sbjct: 270 P-YDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACD---LL 325
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPE 617
+ LL+++ + RLG+ D E++ H FF+ I+W+ + K++ PPF P++ D +FDPE
Sbjct: 326 QSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPE 385
Query: 618 FTQTSTSFMNKQPIAATP----LSPAMQAKFVGFTFVDE 652
FTQ + S + I TP S + F+GF++ E
Sbjct: 386 FTQEAVS----KSIGCTPDTVASSSGASSAFLGFSYAPE 420
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 284 bits (727), Expect = 3e-76
Identities = 160/346 (46%), Positives = 220/346 (63%), Gaps = 22/346 (6%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKK-NEIAHTIGERNI 376
GP FE+LR+LGKG +G+V+QVRK + +IYAMKVL K IV+ + AHT ERNI
Sbjct: 76 GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNI 135
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L S PFIV L ++FQT LYL+ + +SGGELF HL++EG F ED A FY+AE+
Sbjct: 136 L---ESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEIT 192
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPE 494
LAL +LH I+YRDLKPENI+L + G+I L DFGL K + + T+TFCGT EY+APE
Sbjct: 193 LALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPE 252
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
+L+ +G+ + VD+WSLG L+++M G PF A + +K KI GK+ P L+P+ R
Sbjct: 253 ILV-RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALP-PYLTPDAR 310
Query: 555 SFVKGLLNRNPKHRL-GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSN 613
VK L RNP R+ G D +++ HPFF ++W+ + ++ PPF+P L SE D S
Sbjct: 311 DLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQ 370
Query: 614 FDPEFTQTSTSFMNKQPIAA---TPLSPAMQAKFVGFTFVDESAID 656
FD FT+ + P+ + T LS + F+GFT+V S +D
Sbjct: 371 FDTRFTR-------QTPVDSPDDTALSESANQAFLGFTYVAPSVLD 409
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 284 bits (726), Expect = 4e-76
Identities = 169/374 (45%), Positives = 230/374 (61%), Gaps = 23/374 (6%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKK-NEIAHTIGERNIL 377
P+ FE+LR+LGKG +G+V+QVRK +T +I+AMKVL K +IV+ + AHT ERNIL
Sbjct: 88 PECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNIL 147
Query: 378 VRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVL 437
PFIV L ++FQT LYL+ +++SGGELF L++EG F ED A FY+AE+ +
Sbjct: 148 EEV---KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISM 204
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPEL 495
AL +LH I+YRDLKPENI+L+ G++ L DFGL K + D T+TFCGT EY+APE+
Sbjct: 205 ALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEI 264
Query: 496 LMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRS 555
LM +G+ + VD+WSLG L+++M G PF + +K KI K+ P L+ E R
Sbjct: 265 LM-RSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLP-PYLTQEARD 322
Query: 556 FVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNF 614
+K LL RN RLGA D E++AHPFF I+WE + +K+ PPFKP L SE D S F
Sbjct: 323 LLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF 382
Query: 615 DPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNNRKFLQNSYF 674
D +FT+ + P +T LS + F+GFT+V S ++ KF
Sbjct: 383 DSKFTRQTPV---DSPDDST-LSESANQVFLGFTYVAPSVLES------VKEKFSFEPKI 432
Query: 675 MEPGSFIPGNPNLP 688
P FI G+P P
Sbjct: 433 RSPRRFI-GSPRTP 445
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 281 bits (718), Expect = 3e-75
Identities = 142/303 (46%), Positives = 210/303 (68%), Gaps = 8/303 (2%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
+K DF+ L++LG+GTFG+V R+K + ++YA+K++ K+++V ++E+AHT+ E
Sbjct: 171 RKNTVTMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENR 230
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
+L PF+ LK+SFQ + V +F +GGELF HLQ+ F+E R +FY +E+
Sbjct: 231 VLYACVH---PFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEI 287
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAP 493
+LAL YLH +IVYRD+K EN+LLD +G+I + DFGL K ++K D+T+TFCGT EYLAP
Sbjct: 288 ILALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAP 347
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
E++ ++ Y + VD+W +GV+++EM CG PF A +N K+++ I +KFP + LSPE
Sbjct: 348 EVI-EDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFP-NRLSPEA 405
Query: 554 RSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
+ + GLL R P RLGA DD RE+ FF D+DWEA +K++ PPFKP+++SETDTS
Sbjct: 406 VTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTS 465
Query: 613 NFD 615
FD
Sbjct: 466 FFD 468
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 281 bits (718), Expect = 3e-75
Identities = 156/357 (43%), Positives = 226/357 (62%), Gaps = 22/357 (6%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSK-KVIVKKNE 366
E + K + GP+DFE+ ++LGKG +G+V+QVRK +D + +AMKVL K ++ + +
Sbjct: 63 ENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKD 122
Query: 367 IAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTED 426
AHT ERNIL + PFIV L ++FQT LYL+ +++SGGELF HL++EG F ED
Sbjct: 123 TAHTRAERNIL---EAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLED 179
Query: 427 RAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTF 484
FY++E++LAL +LH I+YRDLKPENILLDA G++ L DFGL K +++ T+TF
Sbjct: 180 TTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTF 239
Query: 485 CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF 544
CGT EY+APE+L +G+ K VD+WSLG L+F+M G PF A + +K + I K+
Sbjct: 240 CGTIEYMAPEIL-TRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNL 298
Query: 545 PRDVLSPEGRSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKP 603
P L+PE R V+ L+ R RLG+ +D ++ HPFF ++W+ V +++ PP KP
Sbjct: 299 PA-YLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKP 357
Query: 604 HLISETDTSNFDPEFTQTSTSFMNKQPIAA---TPLSPAMQAKFVGFTFVDESAIDE 657
L SE D S FD FT+ + P+ + T LS + F GFT+V S +++
Sbjct: 358 LLRSEDDVSQFDTRFTR-------QIPVDSPDDTTLSESANLIFQGFTYVAPSILED 407
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 280 bits (715), Expect = 7e-75
Identities = 148/333 (44%), Positives = 214/333 (63%), Gaps = 9/333 (2%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
P DF L+++GKG+FG+V R K YA+KVL KK I+KK E H + ERN+L++
Sbjct: 95 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 154
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
PF+VGL FSFQT LY V D+++GGELF+HLQ+E F E RA+FY AE+ AL Y
Sbjct: 155 KH--PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGY 212
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLMDE 499
LH +IVYRDLKPENILLD+ G+I L DFGL K +++ T+TFCGT EYLAPE+L +
Sbjct: 213 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
Y + VD+W LG +++EM G PF++ + +MY I ++ ++ + R ++G
Sbjct: 273 P-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN-SARHLLEG 330
Query: 560 LLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFT 619
LL ++ RLGA DD E+++H FF+ I+W+ + KKI PPF P++ + +FDPEFT
Sbjct: 331 LLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDPEFT 390
Query: 620 QTST-SFMNKQPIAATPLSPAMQA--KFVGFTF 649
+ + + K P + + +A F+GF++
Sbjct: 391 EEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSY 423
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 278 bits (710), Expect = 3e-74
Identities = 163/342 (47%), Positives = 217/342 (62%), Gaps = 17/342 (4%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
P+ FE+L++LG+G+FG+V+ VRK +D+ +YAMKVL KK +K + T ERNIL
Sbjct: 101 PRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL-KKATLKVRDRQRTKLERNIL- 158
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
A S PFIV L ++FQT LYL+ DF+ GG+LF L KE FTED KFY+AEL LA
Sbjct: 159 --AHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLA 216
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELL 496
LE+LH IVYRDLKPENILLDA+G+I + DFGLSK D + +T +FCGT EY+APE++
Sbjct: 217 LEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVI 276
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
+ G++ DFWSLGVL+FEM G PF D +I K+ P L+ E +S
Sbjct: 277 -NRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPH-FLTQEAQSL 334
Query: 557 VKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
++ L RN ++RLGA DG E++ H FF ID+ + K+I PPFKP L + TS FD
Sbjct: 335 LRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFD 394
Query: 616 PEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDE 657
PEFT+ + + A P S F GF+FV + ++E
Sbjct: 395 PEFTKRT-----PKDSPALPASANGHEIFRGFSFVSNAVMEE 431
Score = 119 bits (298), Expect = 2e-26
Identities = 91/342 (26%), Positives = 155/342 (44%), Gaps = 33/342 (9%)
Query: 315 TKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGER 374
T K D+E+L +G G V++ + K T R YA+K++ K V E+
Sbjct: 444 TAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEV------- 496
Query: 375 NILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHL-QKEGRFTEDRAKFYIA 433
+IL+R + F+V L ++ T +Y++ + GGEL L K+ +E +A
Sbjct: 497 DILLRHSHHQ--FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA 554
Query: 434 ELVLALEYLHDNDIVYRDLKPENILLDAN----GNIALCDFGLSKADLKDR--TNTFCGT 487
L+ A++YLH + +RDL NIL ++ + DFG +K + T C T
Sbjct: 555 NLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYT 614
Query: 488 TEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDN---QKMYQKIAFGKVKF 544
+++APE+L + GY + D WSLGVL+ M G +PF N ++ Q++ GK+
Sbjct: 615 AQFVAPEVLRKQ-GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 673
Query: 545 PR---DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPF 601
D +S E + V+ +L+ +P R+ A ++ H W ++ P
Sbjct: 674 THPVWDTISDEAKDLVRKMLDVDPNRRVTA----KQALQH------KWIGQKEALPDRPI 723
Query: 602 KPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAK 643
+ + E D N QT + + + P+ + AK
Sbjct: 724 QSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAK 765
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 278 bits (710), Expect = 3e-74
Identities = 163/342 (47%), Positives = 217/342 (62%), Gaps = 17/342 (4%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
P+ FE+L++LG+G+FG+V+ VRK +D+ +YAMKVL KK +K + T ERNIL
Sbjct: 44 PRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL-KKATLKVRDRQRTKLERNIL- 101
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
A S PFIV L ++FQT LYL+ DF+ GG+LF L KE FTED KFY+AEL LA
Sbjct: 102 --AHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLA 159
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELL 496
LE+LH IVYRDLKPENILLDA+G+I + DFGLSK D + +T +FCGT EY+APE++
Sbjct: 160 LEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVI 219
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
+ G++ DFWSLGVL+FEM G PF D +I K+ P L+ E +S
Sbjct: 220 -NRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPH-FLTQEAQSL 277
Query: 557 VKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
++ L RN ++RLGA DG E++ H FF ID+ + K+I PPFKP L + TS FD
Sbjct: 278 LRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFD 337
Query: 616 PEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDE 657
PEFT+ + + A P S F GF+FV + ++E
Sbjct: 338 PEFTKRT-----PKDSPALPASANGHEIFRGFSFVSNAVMEE 374
Score = 119 bits (298), Expect = 2e-26
Identities = 91/342 (26%), Positives = 155/342 (44%), Gaps = 33/342 (9%)
Query: 315 TKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGER 374
T K D+E+L +G G V++ + K T R YA+K++ K V E+
Sbjct: 387 TAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEV------- 439
Query: 375 NILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHL-QKEGRFTEDRAKFYIA 433
+IL+R + F+V L ++ T +Y++ + GGEL L K+ +E +A
Sbjct: 440 DILLRHSHHQ--FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA 497
Query: 434 ELVLALEYLHDNDIVYRDLKPENILLDAN----GNIALCDFGLSKADLKDR--TNTFCGT 487
L+ A++YLH + +RDL NIL ++ + DFG +K + T C T
Sbjct: 498 NLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYT 557
Query: 488 TEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDN---QKMYQKIAFGKVKF 544
+++APE+L + GY + D WSLGVL+ M G +PF N ++ Q++ GK+
Sbjct: 558 AQFVAPEVLRKQ-GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 616
Query: 545 PR---DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPF 601
D +S E + V+ +L+ +P R+ A ++ H W ++ P
Sbjct: 617 THPVWDTISDEAKDLVRKMLDVDPNRRVTA----KQALQH------KWIGQKEALPDRPI 666
Query: 602 KPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAK 643
+ + E D N QT + + + P+ + AK
Sbjct: 667 QSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAK 708
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 276 bits (706), Expect = 8e-74
Identities = 147/338 (43%), Positives = 210/338 (61%), Gaps = 11/338 (3%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
P DF+ L+++GKG+FG+V ++K ++YA+KVL KK+++ + E H + ERN+L++
Sbjct: 41 PTDFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNV 100
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
PF+VGL +SFQT LY V DF++GGELF+HLQ+E F E RA+FY AE+ AL Y
Sbjct: 101 KH--PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGY 158
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSKAD--LKDRTNTFCGTTEYLAPELLMDE 499
LH IVYRDLKPENIL+D+ G++ L DFGL K + D T TFCGT EYLAPE++ +
Sbjct: 159 LHSIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ 218
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
Y VD+W LG +++EM G PF+ D +MY I + R +S S ++
Sbjct: 219 P-YDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSL-RPGVSLRAWSILEE 276
Query: 560 LLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFT 619
LL ++ ++RLGA +D E++ HPFF + W + QKKIPPPF P++ D NFD FT
Sbjct: 277 LLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFT 336
Query: 620 QTSTSF----MNKQPIAATPLSPAMQAKFVGFTFVDES 653
+ + + + I + A A FVGF++ S
Sbjct: 337 EETVPYSVCVSSDYSIVNASVLEADDA-FVGFSYAPPS 373
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 274 bits (701), Expect = 3e-73
Identities = 150/332 (45%), Positives = 214/332 (64%), Gaps = 12/332 (3%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G +DFEVL+++G+G FG+VYQVRKKDT IYAMKV+ K IV+KN + ER+IL +
Sbjct: 136 GIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKI 195
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
PFIV LK+SFQT LYLV DF++GG LF+ L +G F ED A+ Y AE+V A+
Sbjct: 196 ---DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVS 252
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA-DLKDRTNTFCGTTEYLAPELLMDE 499
+LH+ I++RDLKPENIL+D +G++ L DFGL+K + R+N+ CGTTEY+APE++ +
Sbjct: 253 HLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGK 312
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
G+ K D+WS+G+L++EM G PF S K+ QKI K+K P+ LS E + +KG
Sbjct: 313 -GHDKAADWWSVGILLYEMLTGKPPFLGSKG-KIQQKIVKDKIKLPQ-FLSNEAHALLKG 369
Query: 560 LLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEF 618
LL + P+ RLG+ G E++ H +F I+W+ + +++ P FKP + +NFD +
Sbjct: 370 LLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFDKCW 429
Query: 619 TQTSTSFMNKQPIAATPLSPAMQAKFVGFTFV 650
T S A++P S A F FT+V
Sbjct: 430 TDMSV----LDSPASSPNSDAKANPFTNFTYV 457
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 272 bits (696), Expect = 1e-72
Identities = 159/344 (46%), Positives = 216/344 (62%), Gaps = 21/344 (6%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
P FE+L++LG+G+FG+V+ V+K D ++YAMKVL KK +K + T ER+ILV
Sbjct: 65 PSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVL-KKATLKVRDRVRTKMERDILV 123
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
+ PFIV L ++FQT LYL+ DF+ GG+LF L KE FTE+ KFY+AEL LA
Sbjct: 124 EV---NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 180
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELL 496
L++LH I+YRDLKPENILLD G+I L DFGLSK D + + +FCGT EY+APE +
Sbjct: 181 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPE-V 239
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
++ G+T+ D+WS GVL+FEM G PF D ++ I K+ P+ LSPE +S
Sbjct: 240 VNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQ-FLSPEAQSL 298
Query: 557 VKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
++ L RNP +RLGA DG E++ H FF+ IDW + +++I PPFKP DT FD
Sbjct: 299 LRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFD 358
Query: 616 PEFTQTSTSFMNKQPIAATPLSPAMQAK--FVGFTFVDESAIDE 657
PEFT K P + + P+ A F GF+FV ++ DE
Sbjct: 359 PEFTA-------KTPKDSPGIPPSANAHQLFRGFSFVAITSDDE 395
Score = 112 bits (281), Expect = 2e-24
Identities = 88/294 (29%), Positives = 144/294 (48%), Gaps = 28/294 (9%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+EV +G G++ + K T +A+K++ K EI IL+R
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEI-------EILLRYGQH- 473
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ LK + +Y+VT+ M GGEL + ++ F+E A + + +EYLH
Sbjct: 474 -PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHA 532
Query: 445 NDIVYRDLKPENIL-LDANGN---IALCDFGLSKADLKDR--TNTFCGTTEYLAPELLMD 498
+V+RDLKP NIL +D +GN I +CDFG +K + T C T ++APE+L
Sbjct: 533 QGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR 592
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDN---QKMYQKIAFGKVKFPR---DVLSPE 552
+ GY D WSLGVL++ M G++PF + +++ +I GK + +S
Sbjct: 593 Q-GYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDT 651
Query: 553 GRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLI 606
+ V +L+ +P RL A + HP+ + W+ + Q ++ PHL+
Sbjct: 652 AKDLVSKMLHVDPHQRLTA----ALVLRHPWI--VHWDQLPQYQLNRQDAPHLV 699
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 271 bits (692), Expect = 3e-72
Identities = 159/344 (46%), Positives = 215/344 (62%), Gaps = 21/344 (6%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
P FE+L++LG+G++G+V+ VRK D ++YAMKVL KK +K + + ER+IL
Sbjct: 56 PSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVL-KKATLKVRDRVRSKMERDIL- 113
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
A + PFIV L ++FQT LYL+ DF+ GG+LF L KE FTE+ KFY+AEL LA
Sbjct: 114 --AEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 171
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELL 496
L++LH I+YRDLKPENILLD G+I + DFGLSK D R +FCGT EY+APE +
Sbjct: 172 LDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPE-V 230
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
++ G+T+ D+WS GVL+FEM G PF D ++ I K+ P+ LS E +S
Sbjct: 231 VNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQ-FLSGEAQSL 289
Query: 557 VKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
++ L RNP +RLGA ID E++ HPFF IDW + +K+I PPFKP + DT +FD
Sbjct: 290 LRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFD 349
Query: 616 PEFTQTSTSFMNKQPIAATPLSPAMQAK--FVGFTFVDESAIDE 657
PEFT + P + + P+ A F GF+FV S I E
Sbjct: 350 PEFTA-------RTPTDSPGVPPSANAHHLFRGFSFVASSLIQE 386
Score = 106 bits (264), Expect = 1e-22
Identities = 82/272 (30%), Positives = 134/272 (49%), Gaps = 28/272 (10%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ +G G++ + K T YA+K++ K EI IL+R
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEI-------EILLRYGQH- 466
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ LK + +YLV + M GGEL + ++ F+E A + + ++YLH
Sbjct: 467 -PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHS 525
Query: 445 NDIVYRDLKPENILL-DANG---NIALCDFGLSKADLKDRTN---TFCGTTEYLAPELLM 497
+V+RDLKP NIL D +G +I +CDFG +K L+ T C T ++APE+L
Sbjct: 526 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAK-QLRAGNGLLMTPCYTANFVAPEVLK 584
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDN---QKMYQKIAFGKVKFPR---DVLSP 551
+ GY D WSLG+L++ M G++PF + +++ +I GK D +S
Sbjct: 585 RQ-GYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISD 643
Query: 552 EGRSFVKGLLNRNPKHRLGAIDDGRELRAHPF 583
+ V +L+ +P RL A+ ++ HP+
Sbjct: 644 AAKDVVSKMLHVDPHQRLTAM----QVLKHPW 671
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 270 bits (691), Expect = 4e-72
Identities = 146/332 (43%), Positives = 212/332 (62%), Gaps = 12/332 (3%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G DFEV++++GKG FG+VYQVRKK+T IYAMKV+ K I++KN + ER+IL +
Sbjct: 130 GIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKI 189
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
PFIV LK+SFQT LYLV DF++GG LF+ L +G F ED A+ Y AE+V A+
Sbjct: 190 ---DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVS 246
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA-DLKDRTNTFCGTTEYLAPELLMDE 499
+LH+ I++RDLKPENIL+D +G++ L DFGL+K + R+N+ CGTTEY+APE++ +
Sbjct: 247 HLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGK 306
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
G+ K D+WS+G+L++EM G PF S K+ QKI K+K P+ LS E + +KG
Sbjct: 307 -GHDKAADWWSVGILLYEMLTGKPPFLGSKG-KIQQKIVKDKIKLPQ-FLSNEAHAILKG 363
Query: 560 LLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEF 618
LL + P+ RLG+ + E++ H +F I+W+ + +++ P FKP + +NFD +
Sbjct: 364 LLQKEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFDKCW 423
Query: 619 TQTSTSFMNKQPIAATPLSPAMQAKFVGFTFV 650
T S A++P S F FT+V
Sbjct: 424 TDMSV----LDSPASSPSSDPKANPFTNFTYV 451
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 265 bits (678), Expect = 1e-70
Identities = 135/293 (46%), Positives = 196/293 (66%), Gaps = 7/293 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF+ ++ LG G+FG+V V+ K + YAMK+L K+ +VK ++ HT+ E+ IL +
Sbjct: 51 DFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRIL---QAI 107
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V + FSF+ ++LY+V +F+SGGE+F HL++ GRF+E ++FY A++VLA EYLH
Sbjct: 108 DFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH 167
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYT 503
D++YRDLKPEN+L+D+ G + + DFG +K +K RT T CGT EYLAPE+++ + GY
Sbjct: 168 SLDLIYRDLKPENLLIDSTGYLKITDFGFAKR-VKGRTWTLCGTPEYLAPEIILSK-GYN 225
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
K VD+W+LGVLI+EM G+ PFFA ++Y+KI GKVKFP S E + +K LL
Sbjct: 226 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSH-FSNELKDLLKNLLQV 284
Query: 564 NPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
+ R G + +G +++ H +F DW A+ QKKI PF P D SNFD
Sbjct: 285 DLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFD 337
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 264 bits (675), Expect = 3e-70
Identities = 137/312 (43%), Positives = 204/312 (64%), Gaps = 9/312 (2%)
Query: 305 DILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKK 364
D L WE + + G +DFE + LG G+FG+V V+ K T + YAMK+L K+ +VK
Sbjct: 26 DFLKKWE--NPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 365 NEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFT 424
+I HT+ E+ IL + + PF+V L+++F+ ++LY+V +++ GGE+F HL++ GRF+
Sbjct: 84 KQIEHTLNEKRIL---QAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFS 140
Query: 425 EDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF 484
E A+FY A++VL EYLH D++YRDLKPEN+L+D G I + DFG +K +K RT T
Sbjct: 141 EPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR-VKGRTWTL 199
Query: 485 CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF 544
CGT EYLAPE+++ + GY K VD+W+LGVLI+EM G+ PFFA ++Y+KI GKV+F
Sbjct: 200 CGTPEYLAPEIILSK-GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRF 258
Query: 545 PRDVLSPEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKP 603
P S + + ++ LL + R G + +G +++ H +F DW A+ Q+K+ PF P
Sbjct: 259 PSH-FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 317
Query: 604 HLISETDTSNFD 615
DTSNFD
Sbjct: 318 KFRGSGDTSNFD 329
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 263 bits (671), Expect = 9e-70
Identities = 153/342 (44%), Positives = 212/342 (61%), Gaps = 17/342 (4%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKK---DTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
P FE+L++LG+G+FG+V+ VRKK D ++YAMKVL KK +K + T ER+ILV
Sbjct: 70 PAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVL-KKASLKVRDRVRTKMERDILV 128
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
+ PFIV L ++FQT LYL+ DF+ GG++F L KE FTE+ KFY+AEL LA
Sbjct: 129 EV---NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALA 185
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELL 496
L++LH IVYRDLKPENILLD G+I L DFGLSK D + + +FCGT EY+APE +
Sbjct: 186 LDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPE-V 244
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
++ G+++ D+WS GVL+FEM G PF D + I K+ P+ LS E +S
Sbjct: 245 VNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQ-FLSAEAQSL 303
Query: 557 VKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP 616
++ L RNP +RLG+ + E++ H FF +IDW+ + ++++ PPFKP DT FDP
Sbjct: 304 LRMLFKRNPANRLGS-EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDP 362
Query: 617 EFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEH 658
EFT + + P S F GF+FV S +E+
Sbjct: 363 EFTAKT-----PKDSPGLPASANAHQLFKGFSFVATSIAEEY 399
Score = 107 bits (266), Expect = 9e-23
Identities = 84/266 (31%), Positives = 131/266 (48%), Gaps = 25/266 (9%)
Query: 319 QYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
Q+G + +E+ +G G++ + T +A+K++ K EI IL+
Sbjct: 421 QFG-EVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEI-------EILM 472
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
R P I+ LK F +YLVTD M GGEL + K+ F+E A + +
Sbjct: 473 RYGQH--PNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKT 530
Query: 439 LEYLHDNDIVYRDLKPENIL-LDANG---NIALCDFGLSKADLKDRTN---TFCGTTEYL 491
++YLH +V+RDLKP NIL +D + +I +CDFG +K L+ T C T ++
Sbjct: 531 VDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAK-QLRGENGLLLTPCYTANFV 589
Query: 492 APELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDN---QKMYQKIAFGKVKFPR-- 546
APE+LM + GY D WSLGVL + M G++PF N +++ +I GK
Sbjct: 590 APEVLMQQ-GYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGN 648
Query: 547 -DVLSPEGRSFVKGLLNRNPKHRLGA 571
D +S + + +L+ +P R A
Sbjct: 649 WDNISDGAKDLLSHMLHMDPHQRYTA 674
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 263 bits (671), Expect = 9e-70
Identities = 153/334 (45%), Positives = 207/334 (61%), Gaps = 17/334 (5%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
P FE+LR+LG+G+FG+V+ VRK KD +YAMKVL K + K+ + T ER IL
Sbjct: 196 PSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRST-NERKIL- 253
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
A FIV L ++FQTP LYL+ DF+ GG+LF L KE FTE+ KFY+AEL LA
Sbjct: 254 --ADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 311
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK-DRTNTFCGTTEYLAPELLM 497
+ +LH I+YRDLKPENILLD +G+IAL DFGLSK L +T +FCGT EY+APE ++
Sbjct: 312 MNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPE-IV 370
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
+ G+ D+WS GVL++EM G PF Q+ +I K+ P + LSPE +S +
Sbjct: 371 NRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPEN-LSPEAQSLL 429
Query: 558 KGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP 616
+ L RNP++RLGA G +++AH FF IDW + +K++ PPF P +S D FD
Sbjct: 430 RALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIP-AVSRDDAFYFDV 488
Query: 617 EFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFV 650
E+T S + P+S + F GF+FV
Sbjct: 489 EYTSKS-----PRDSPGGPISASAHEIFRGFSFV 517
Score = 106 bits (265), Expect = 1e-22
Identities = 70/257 (27%), Positives = 125/257 (48%), Gaps = 13/257 (5%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++ +L+ LG+GTF + + + YA+KV+ K + + + +
Sbjct: 567 EYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYG 626
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+ P IV L ++ YLV + + GGEL + G+ E A + + A+ YLH
Sbjct: 627 NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLH 686
Query: 444 DNDIVYRDLKPENILL----DANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLM 497
++ +V+RDLKP N++ + LCD G +K D T C T ++APE+L
Sbjct: 687 EHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLK 746
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQK---MYQKIAFGKVKFPRD---VLSP 551
+ GY D WSLGVL++ M G +PF ++ N + ++I G++ F ++S
Sbjct: 747 RQ-GYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWALISV 805
Query: 552 EGRSFVKGLLNRNPKHR 568
+ ++ +L+ P++R
Sbjct: 806 PAKELLRQMLHIVPENR 822
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 262 bits (670), Expect = 1e-69
Identities = 138/312 (44%), Positives = 202/312 (64%), Gaps = 9/312 (2%)
Query: 305 DILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKK 364
D L WE S + FE ++ LG G+FG+V V+ K+T YAMK+L K+ +VK
Sbjct: 26 DFLKKWE--SPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL 83
Query: 365 NEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFT 424
+I HT+ E+ IL + + PF+V L+FSF+ ++LY+V +++ GGE+F HL++ GRF+
Sbjct: 84 KQIEHTLNEKRIL---QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFS 140
Query: 425 EDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF 484
E A+FY A++VL EYLH D++YRDLKPEN+L+D G I + DFG +K +K RT T
Sbjct: 141 EPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-VKGRTWTL 199
Query: 485 CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF 544
CGT EYLAPE+++ + GY K VD+W+LGVLI+EM G+ PFFA ++Y+KI GKV+F
Sbjct: 200 CGTPEYLAPEIILSK-GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRF 258
Query: 545 PRDVLSPEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKP 603
P S + + ++ LL + R G + +G +++ H +F DW A+ Q+K+ PF P
Sbjct: 259 PSH-FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317
Query: 604 HLISETDTSNFD 615
DTSNFD
Sbjct: 318 KFKGPGDTSNFD 329
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 262 bits (669), Expect = 2e-69
Identities = 142/331 (42%), Positives = 207/331 (61%), Gaps = 8/331 (2%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+DF+ L +LG+G FG+V + + ++A+K L K IV ++E+ + E+ IL S
Sbjct: 613 EDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTS 672
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
PF+V L FQTP + V ++ +GG+L H+ + F+E RA FY A +VL L++L
Sbjct: 673 AGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSD-VFSEPRAIFYSACVVLGLQFL 731
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDET 500
H++ IVYRDLK +N+LLD G + + DFGL K + DRT+TFCGT E+LAPE+L D T
Sbjct: 732 HEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD-T 790
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
YT+ VD+W LGVL++EM G SPF D ++++ I +V++PR LS E ++ L
Sbjct: 791 SYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPR-FLSAEAIGIMRRL 849
Query: 561 LNRNPKHRLGAID-DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFT 619
L RNP+ RLG+ + D +++ PFF + WEA+ +++PPPF P L TD SNFD EFT
Sbjct: 850 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFT 909
Query: 620 QTSTSFMNKQPIAATPLSPAMQAKFVGFTFV 650
+ + P A PL+ A QA F+ F FV
Sbjct: 910 GEAPTL--SPPRDARPLTAAEQAAFLDFDFV 938
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 262 bits (669), Expect = 2e-69
Identities = 142/331 (42%), Positives = 207/331 (61%), Gaps = 8/331 (2%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+DF+ L +LG+G FG+V + + ++A+K L K IV ++E+ + E+ IL S
Sbjct: 613 EDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTS 672
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
PF+V L FQTP + V ++ +GG+L H+ + F+E RA FY A +VL L++L
Sbjct: 673 AGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSD-VFSEPRAIFYSACVVLGLQFL 731
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDET 500
H++ IVYRDLK +N+LLD G + + DFGL K + DRT+TFCGT E+LAPE+L D T
Sbjct: 732 HEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD-T 790
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
YT+ VD+W LGVL++EM G SPF D ++++ I +V++PR LS E ++ L
Sbjct: 791 SYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPR-FLSAEAIGIMRRL 849
Query: 561 LNRNPKHRLGAID-DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFT 619
L RNP+ RLG+ + D +++ PFF + WEA+ +++PPPF P L TD SNFD EFT
Sbjct: 850 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFT 909
Query: 620 QTSTSFMNKQPIAATPLSPAMQAKFVGFTFV 650
+ + P A PL+ A QA F+ F FV
Sbjct: 910 GEAPTL--SPPRDARPLTAAEQAAFLDFDFV 938
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 262 bits (669), Expect = 2e-69
Identities = 144/348 (41%), Positives = 217/348 (61%), Gaps = 20/348 (5%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
+RQY DFE++R++G+G++ +V V + T RIYAMKV+ K ++ +I E+++
Sbjct: 253 QRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHV 312
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
TAS + PF+VGL FQTP+ L+ V +F+ GG+L +H+Q++ R E+ A+FY AE+
Sbjct: 313 F-ETAS-NHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEIS 370
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPE 494
LAL +LH+ I+YRDLK +N+LLD G+I L D+G+ K ++ D T+TFCGT Y+APE
Sbjct: 371 LALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPE 430
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPF---FASDN------QKMYQKIAFGKVKFP 545
+L E Y VD+W+LGVL++EM G SPF AS+N ++Q I ++ P
Sbjct: 431 ILRGE-DYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIP 489
Query: 546 RDVLSPEGRSFVKGLLNRNPKHRLGAIDDG--RELRAHPFFNDIDWEAVRQKKIPPPFKP 603
R LS S +KG LN+NP RLG + ++ +HPFF ++DWE + +K++ PPFKP
Sbjct: 490 RS-LSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKP 548
Query: 604 HLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVD 651
L S+ D +NF PEFT + P + Q++F GF +V+
Sbjct: 549 RLDSDRDLANFPPEFTGEAVQL---TPDDDHVIDNIDQSEFEGFEYVN 593
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 262 bits (669), Expect = 2e-69
Identities = 137/330 (41%), Positives = 203/330 (61%), Gaps = 9/330 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF +++LGKG+FG+V KK T IYA+KVL K I++ +++ T+ E+ IL A+
Sbjct: 407 DFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANH 466
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+ L FQTP L+ V ++++GG+L + +QK RF RA FY AE+ LAL++LH
Sbjct: 467 --PFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLH 524
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLMDETG 501
+ ++YRDLK +NILLD G+ L DFG+ K + + T TFCGT +Y+APE+L ++
Sbjct: 525 THGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQE- 583
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y VD+W+LGVL++EM G PF A + +++ I V +P LS E S +KG L
Sbjct: 584 YGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYP-VWLSREAVSILKGFL 642
Query: 562 NRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQT 621
+NP+ RLG D E+R HPFF +DW+ + ++ I PPF+P + + D +NFD EFT+
Sbjct: 643 TKNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKE 702
Query: 622 STSFMNKQPIAATPLSPAMQAKFVGFTFVD 651
PI + Q +F GF+FV+
Sbjct: 703 DPVL---TPIGNEVVRCINQDEFAGFSFVN 729
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 261 bits (666), Expect = 4e-69
Identities = 149/352 (42%), Positives = 220/352 (62%), Gaps = 24/352 (6%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKK---DTMRIYAMKVLSKKVIVKKNEIA-HTIGERNILV 378
++FE+L++LG G +G+V+ VRK D ++YAMKVL K +V++ + HT ER++L
Sbjct: 31 ENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLE 90
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
+ +PF+V L ++FQT L+L+ D++SGGE+F HL + F E + Y E+VLA
Sbjct: 91 LV--RQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLA 148
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL---KDRTNTFCGTTEYLAPEL 495
LE+LH I+YRDLK EN+LLD+ G+I L DFGLSK L K+RT +FCGT EY+APE+
Sbjct: 149 LEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEI 208
Query: 496 LMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVK----FPRDVLSP 551
+ +TG+ K VD+WSLG+L+FE+ G SPF + +++ +K FP + P
Sbjct: 209 IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRI-GP 267
Query: 552 EGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETD 610
+ ++ LL ++PK RLGA G +E+R HPFF +DW A+ +KIP PF+P + SE D
Sbjct: 268 VAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELD 327
Query: 611 TSNFDPEFTQTSTSFMNKQPIAATPLS--PAMQAKFVGFTFVDESAIDEHYN 660
NF EFT+ +P+ + P S P F G++FV S + +H N
Sbjct: 328 VGNFAEEFTRL-------EPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNN 372
Score = 112 bits (279), Expect = 3e-24
Identities = 79/256 (30%), Positives = 129/256 (49%), Gaps = 26/256 (10%)
Query: 331 LGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVG 390
LG+G+F + R++ + + +A+K+LS+++ +R + +S P +V
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANT--------QREVAALRLCQSHPNVVN 468
Query: 391 LKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDN-DIVY 449
L YLV + + GGEL H++K+ F+E A + LV A+ ++H+ +V+
Sbjct: 469 LHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVH 528
Query: 450 RDLKPENILL--DANG-NIALCDFGLSKADLKD---RTNTFCGTTEYLAPELLMDETGYT 503
RDLKPENIL D G + + DFG ++ + T C T +Y APELL + GY
Sbjct: 529 RDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQ-GYD 587
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQ-------KMYQKIAFGKVKFPRDV---LSPEG 553
+ D WSLGV+++ M G PF + Q ++ KI G+ + +S E
Sbjct: 588 ESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEA 647
Query: 554 RSFVKGLLNRNPKHRL 569
+ V+GLL +P RL
Sbjct: 648 KELVRGLLTVDPAKRL 663
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 260 bits (665), Expect = 5e-69
Identities = 149/448 (33%), Positives = 243/448 (53%), Gaps = 39/448 (8%)
Query: 234 RGSINPVWEHEATFDVLGTHSELDISI----YDAAQDDMFLGQVRLHPNMNAVTPGVHSE 289
+ +NPVW T+D+ + I I +D + F+G + ++ + +
Sbjct: 234 KACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSF--GISEIIKNPTNG 291
Query: 290 WHKLKSRALGEHVT-------GDILIHWE----------------YTSTKKRQYGPQDFE 326
W KL ++ GE+ D+L + +TS+KK DF
Sbjct: 292 WFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRSDTNTHTSSKKDMIRATDFN 351
Query: 327 VLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSP 386
+++LGKG+FG+V +K + +YA+K+L K VI++ +++ T+ E+ +L + P
Sbjct: 352 FIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLA--LGEKPP 409
Query: 387 FIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDND 446
F+V L FQT L+ V ++++GG+L + +Q+ G+F E A FY AE+ L +LH
Sbjct: 410 FLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKG 469
Query: 447 IVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDETGYTK 504
I+YRDLK +N+LLDA+G++ + DFG+ K ++ T TFCGT +Y+APE+++ + Y K
Sbjct: 470 ILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQP-YGK 528
Query: 505 MVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRN 564
VD+W+ GVL++EM G PF D ++++ I V +P+ LS E + KG L +
Sbjct: 529 SVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKS-LSKEAKEACKGFLTKQ 587
Query: 565 PKHRLGAIDDGRE-LRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTST 623
P RLG G E +R HPFF IDWE + +++ PPFKP + D SNFD +FT T
Sbjct: 588 PNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKT 647
Query: 624 SFMNKQPIAATPLSPAMQAKFVGFTFVD 651
+ L Q++FVGF++++
Sbjct: 648 DLTPTDKVFMMNLD---QSEFVGFSYMN 672
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 259 bits (663), Expect = 8e-69
Identities = 145/348 (41%), Positives = 221/348 (62%), Gaps = 22/348 (6%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIA-HTIGERNI 376
G ++FE+L++LG G +G+V+ VRK DT ++YAMKVL K IV+K + HT ER +
Sbjct: 45 GIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQV 104
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L + SPF+V L ++FQT T L+L+ D+++GGELF HL + RFTE + Y+ E+V
Sbjct: 105 LEHI--RQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIV 162
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK---ADLKDRTNTFCGTTEYLAP 493
LALE+LH I+YRD+K ENILLD+NG++ L DFGLSK AD +R +FCGT EY+AP
Sbjct: 163 LALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAP 222
Query: 494 ELLM-DETGYTKMVDFWSLGVLIFEMCCGWSPFFA----SDNQKMYQKIAFGKVKFPRDV 548
+++ ++G+ K VD+WSLGVL++E+ G SPF + ++ ++I + +P++
Sbjct: 223 DIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQE- 281
Query: 549 LSPEGRSFVKGLLNRNPKHRLG-AIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLIS 607
+S + ++ LL ++PK RLG D E++ H FF I+W+ + KK+P PFKP +
Sbjct: 282 MSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRD 341
Query: 608 ETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAI 655
E D SNF EFT+ ++ + L + + F G++FV S +
Sbjct: 342 ELDVSNFAEEFTEMDPTY------SPAALPQSSEKLFQGYSFVAPSIL 383
Score = 117 bits (294), Expect = 5e-26
Identities = 85/275 (30%), Positives = 136/275 (48%), Gaps = 32/275 (11%)
Query: 331 LGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVG 390
LG+G+F + K + + +K++SK++ ++ I + P IV
Sbjct: 432 LGEGSFSICRKCVHKKSNQALQVKIISKRMEANT--------QKEITALKLCEGHPNIVK 483
Query: 391 LKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYR 450
L F +LV + ++GGELF L+K+ F+E A + + +LV AL ++HD +V+R
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHR 543
Query: 451 DLKPENILL-DANGN--IALCDFGLSKADLKDR--TNTFCGTTEYLAPELLMDETGYTKM 505
DLKPEN+L D N N I + DFG ++ D T C T PELL ++ GY +
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELL-NQNGYDES 602
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQ-------KMYQKIAFGKVKFPRDV---LSPEGRS 555
D WSLGV+++ M G PF + D ++ +KI G F + +S E +
Sbjct: 603 CDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKD 662
Query: 556 FVKGLLNRNPKHRLGA--------IDDGRELRAHP 582
++GLL +P RL + DG +L ++P
Sbjct: 663 LIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNP 697
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 259 bits (662), Expect = 1e-68
Identities = 142/327 (43%), Positives = 206/327 (62%), Gaps = 26/327 (7%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF+ ++ LG G+FG+V V+ K + YAMK+L K+ +VK ++ HT+ E+ IL +
Sbjct: 51 DFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRIL---QAI 107
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V + FSF+ ++LY+V +F+SGGE+F HL++ GRF+E ++FY A++VLA EYLH
Sbjct: 108 DFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH 167
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYT 503
D++YRDLKPEN+L+D+ G + + DFG +K +K RT T CGT EYLAPE+++ + GY
Sbjct: 168 SLDLIYRDLKPENLLIDSTGYLKITDFGFAKR-VKGRTWTLCGTPEYLAPEIILSK-GYN 225
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
K VD+W+LGVLI+EM G+ PFFA ++Y+KI GKVKFP S E + +K LL
Sbjct: 226 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSH-FSNELKDLLKNLLQV 284
Query: 564 NPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPP--------------FKPHLISE 608
+ R G + +G +++ H +F DW A+ QKKI PP P +
Sbjct: 285 DLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPPSFSKGESNGRLFEALYPRVDGP 344
Query: 609 TDTSNFDPEFTQTSTSFMNKQPIAATP 635
DT +F E Q T F+ IAATP
Sbjct: 345 ADTRHFVEE-VQEPTEFV----IAATP 366
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 259 bits (661), Expect = 1e-68
Identities = 140/350 (40%), Positives = 215/350 (61%), Gaps = 10/350 (2%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
K ++ G +DF L +LGKG FG+V K ++YA+KVL K+ I++ +E+ T E+
Sbjct: 674 KAKRIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKR 733
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
+ + + PF+V L FQT T +Y V DF+SGG+L H+Q+E +F+ RA+FY AE+
Sbjct: 734 VFLVANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFYAAEV 792
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAP 493
LAL+Y HDN I+YRDLK +NILL +G++ + D+GL K D+ + T TFCGT E++AP
Sbjct: 793 CLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAP 852
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
E+L+++ YT+ VD+W+ GVLI++M G SPF D ++++ I + +P + +
Sbjct: 853 EILLEQQ-YTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIH-MPRDS 910
Query: 554 RSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
S ++ LL R+PK RLG+ +D ++ HPFF++I+W+ + K+ PP+ P L S TDT
Sbjct: 911 VSILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDTK 970
Query: 613 NFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNA 662
FD EFT+ I L+ MQ F GF++ E +NA
Sbjct: 971 YFDEEFTRELPVLTPVNSI----LTKEMQQHFEGFSYSCEDDKPSTTDNA 1016
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 259 bits (661), Expect = 1e-68
Identities = 149/342 (43%), Positives = 209/342 (60%), Gaps = 17/342 (4%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
P FE+L++LG+G+FG+V+ VRK D+ +YAMKVL KK +K + T ER+IL
Sbjct: 59 PSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVL-KKATLKVRDRVRTKMERDIL- 116
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
A + PF+V L ++FQT LYL+ DF+ GG+LF L KE FTE+ KFY+AEL L
Sbjct: 117 --ADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALG 174
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELL 496
L++LH I+YRDLKPENILLD G+I L DFGLSK D + + +FCGT EY+APE +
Sbjct: 175 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPE-V 233
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
++ G++ D+WS GVL+FEM G PF D ++ I K+ P+ LS E +S
Sbjct: 234 VNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQ-FLSTEAQSL 292
Query: 557 VKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
++ L RNP +RLG+ DG E++ H F++ IDW + +++I PPFKP + DT FD
Sbjct: 293 LRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFD 352
Query: 616 PEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDE 657
EFT + + P S F GF+FV +++
Sbjct: 353 TEFTSRT-----PKDSPGIPPSAGAHQLFRGFSFVATGLMED 389
Score = 115 bits (288), Expect = 2e-25
Identities = 85/276 (30%), Positives = 138/276 (49%), Gaps = 26/276 (9%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+ V +G G++ + + K T YA+KV+ K EI IL+R
Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEI-------EILLRYGQH- 469
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ LK + +YLVT+ M GGEL + ++ F+E A F + + +EYLH
Sbjct: 470 -PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHS 528
Query: 445 NDIVYRDLKPENIL-LDANGN---IALCDFGLSKADLKDR--TNTFCGTTEYLAPELLMD 498
+V+RDLKP NIL +D +GN + +CDFG +K + T C T ++APE+L
Sbjct: 529 QGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR 588
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFF---ASDNQKMYQKIAFGKVKFPR---DVLSPE 552
+ GY + D WSLG+L++ M G++PF + +++ +I GK + +S
Sbjct: 589 Q-GYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSET 647
Query: 553 GRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDID 588
+ V +L+ +P RL A +++ HP+ D
Sbjct: 648 AKDLVSKMLHVDPHQRLTA----KQVLQHPWVTQKD 679
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 258 bits (658), Expect = 3e-68
Identities = 141/338 (41%), Positives = 212/338 (62%), Gaps = 22/338 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF +++LGKG+FG+V +K T +YA+K+L K VIV+ +++ T+ E+ IL A
Sbjct: 377 DFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKH 436
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+ L SFQT L+ V ++++GG+L + +Q+ +F E RA+FY AE+ AL++LH
Sbjct: 437 --PFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLH 494
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADL-KDR-TNTFCGTTEYLAPELLMDETG 501
ND++YRDLK +NILLDA G+ L DFG+ K + KD T+TFCGT +Y+APE+L E
Sbjct: 495 RNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEIL-QEME 553
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y VD+W+LGVL++EM G PF A + +++ I V +P LS E + +K +
Sbjct: 554 YGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYP-VWLSKEAVNILKAFM 612
Query: 562 NRNPKHRLG-AIDDGRE--LRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEF 618
+N RLG + G E +RAHPFF +IDW+A+ +++ PPFKP + S+ D +NFD +F
Sbjct: 613 TKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDF 672
Query: 619 TQTSTSFMNKQPIAATPLSPAM-----QAKFVGFTFVD 651
T K+ TP PA+ Q +F GF+F++
Sbjct: 673 T--------KEEPVLTPSDPAVVRAINQDEFRGFSFIN 702
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 257 bits (657), Expect = 4e-68
Identities = 137/334 (41%), Positives = 207/334 (61%), Gaps = 11/334 (3%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G +FE +R+LGKG+FG+V R K+T +YA+KVL K VI+ +++ T+ E+ IL +
Sbjct: 350 GIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRIL--S 407
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
+++ PF+ L FQTP L+ V +F++GG+L +H+QK RF E RA+FY AE++ AL
Sbjct: 408 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 467
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLMD 498
+LHD I+YRDLK +N+LLD G+ L DFG+ K + + T TFCGT +Y+APE+L
Sbjct: 468 FLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEIL-Q 526
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVK 558
E Y VD+W++GVL++EM CG +PF A + +++ I +V +P L + +K
Sbjct: 527 EMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP-TWLHEDATGILK 585
Query: 559 GLLNRNPKHRLGAIDDGRE--LRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP 616
+ +NP RLG++ G E + HPFF +IDW + ++I PPF+P + S D SNFDP
Sbjct: 586 SFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDP 645
Query: 617 EFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFV 650
+F + PI L Q +F F++V
Sbjct: 646 DFIKEEPVL---TPIDEGHLPMINQDEFRNFSYV 676
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 257 bits (656), Expect = 5e-68
Identities = 150/347 (43%), Positives = 214/347 (61%), Gaps = 22/347 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSKKVIVKKNEIA-HTIGERNILVR 379
DF+++R+LG G +G+V+ VRK D ++YAMKVL+K +V+K + A HT ER +L
Sbjct: 260 DFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVL-- 317
Query: 380 TASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLAL 439
A + +PF+V L ++FQ+ + LYLV DF +GGELF HL F E R + YIAE+VLAL
Sbjct: 318 EAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLAL 377
Query: 440 EYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK---ADLKDRTNTFCGTTEYLAPELL 496
E LH I+YRD+K ENILLD G+I L DFGLSK A+ + R ++FCGT EY+APE++
Sbjct: 378 EQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEII 437
Query: 497 -MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVL----SP 551
G+ VD+WS+GVL FE+ G SPF SD Q +I+ +++ + ++ S
Sbjct: 438 RTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEIS-RRIQKEQPMIPSSFSA 496
Query: 552 EGRSFVKGLLNRNPKHRLGAID-DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETD 610
R FV +L +NPK RLG D E++ HPFFN I+W+ +R K+ P+KP L +E D
Sbjct: 497 NARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDD 556
Query: 611 TSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDE 657
NF EFT + + P P P+ F G+T+V +++
Sbjct: 557 VQNFSNEFTDQ----VPEDPECDAP--PSRIRLFRGYTYVAPEHLEQ 597
Score = 68.9 bits (167), Expect = 3e-11
Identities = 65/267 (24%), Positives = 116/267 (43%), Gaps = 32/267 (11%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
P D E+ G +G + V T ++ K++ + +E+ I L T
Sbjct: 620 PDDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKF-RPSEVDALIS--CALDTTN 676
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
K+ IV +F+ + ++V +++SG EL + R ED + +LV+A+ +
Sbjct: 677 HKN---IVSYHGTFREKCETWIVMEYLSGPELTASI----RMDEDSCREIFLQLVMAVRH 729
Query: 442 LHDNDIVYRDLKPENILLD--ANGNIALCDFGLSKADLKDRTNTFCG----TTEYLAPEL 495
+H ++ DLKPENI+ + + + L DFG A +R ++ T +Y PE+
Sbjct: 730 IHSKHFIHGDLKPENIMFENREDRTVKLIDFG--SACYNNRFKSWKDKPRYTLDYAPPEM 787
Query: 496 LMDE--TGYTKMVDFWSLGVLIFEMCCGWSPFFASDN------------QKMYQKIAFGK 541
L D Y+ VD + LG ++ M G P+ +++ +K ++ F +
Sbjct: 788 LADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQ 847
Query: 542 VKFPRDVLSPEGRSFVKGLLNRNPKHR 568
+ SP R V L R+P R
Sbjct: 848 RSMRWESASPAFRHLVSWCLQRDPADR 874
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 256 bits (654), Expect = 9e-68
Identities = 142/328 (43%), Positives = 200/328 (60%), Gaps = 13/328 (3%)
Query: 314 STKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGE 373
S ++ Q+ QDF +LG+G FG+V K+T ++A+K L K IV ++E+ + E
Sbjct: 646 SQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCE 705
Query: 374 RNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIA 433
+ I S PF+V L FQT + V ++ +GG+L H+ + F+E RA FY A
Sbjct: 706 KRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTD-VFSEPRAVFYAA 764
Query: 434 ELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYL 491
+VL L+YLH++ IVYRDLK +N+LLD G + + DFGL K + DRT+TFCGT E+L
Sbjct: 765 CVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFL 824
Query: 492 APELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSP 551
APE+L ET YT+ VD+W LGVLI+EM G SPF D ++++ I +V++PR LS
Sbjct: 825 APEVL-TETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPR-FLST 882
Query: 552 EGRSFVKGLLNRNPKHRLGAID-DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETD 610
E S ++ LL RNP+ RLGA + D +++ HPFF IDW A+ KK+ PPF P + D
Sbjct: 883 EAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGRED 942
Query: 611 TSNFDPEFTQTSTSFMNKQPIAATPLSP 638
SNFD EFT ++ PI P P
Sbjct: 943 VSNFDDEFT-------SEAPILTPPREP 963
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 256 bits (653), Expect = 1e-67
Identities = 139/349 (39%), Positives = 219/349 (61%), Gaps = 30/349 (8%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G QDF++LR++G+G++ +V VR K T RIYAMKV+ K+++ +I E+++ +
Sbjct: 241 GLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQA 300
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
++ PF+VGL FQT + L+ V ++++GG+L +H+Q++ + E+ A+FY AE+ LAL
Sbjct: 301 SNH--PFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALN 358
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLMD 498
YLH+ I+YRDLK +N+LLD+ G+I L D+G+ K L+ D T+TFCGT Y+APE+L
Sbjct: 359 YLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRG 418
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPF---FASDN------QKMYQKIAFGKVKFPRDVL 549
E Y VD+W+LGVL+FEM G SPF +SDN ++Q I +++ PR L
Sbjct: 419 E-DYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRS-L 476
Query: 550 SPEGRSFVKGLLNRNPKHRLGAIDDG--RELRAHPFFNDIDWEAVRQKKIPPPFKPHLIS 607
S + S +K LN++PK RLG +++ HPFF ++DW+ + QK++ PPFKP++
Sbjct: 477 SVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISG 536
Query: 608 ETDTSNFDPEFTQTSTSFMNKQPIAATP-----LSPAMQAKFVGFTFVD 651
E NFD +FT +P+ TP + Q++F GF +++
Sbjct: 537 EFGLDNFDSQFT--------NEPVQLTPDDDDIVRKIDQSEFEGFEYIN 577
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 254 bits (650), Expect = 3e-67
Identities = 130/293 (44%), Positives = 193/293 (65%), Gaps = 7/293 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DFE ++ LG G+FG+V V+ K T YAMK+L K+ +VK ++ HT+ E+ IL +
Sbjct: 45 DFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRIL---QAI 101
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V L++ F+ ++LY+V +++ GGE+F HL+K GRF+E ++FY A++VLA EYLH
Sbjct: 102 QFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLH 161
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYT 503
D++YRDLKPEN+L+D+ G + + DFG +K +K RT T CGT EYLAPE+++ + GY
Sbjct: 162 YLDLIYRDLKPENLLIDSQGYLKVTDFGFAKR-VKGRTWTLCGTPEYLAPEIILSK-GYN 219
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
K VD+W+LGVL++EM G+ PFFA ++Y+KI GKV+FP + + ++ LL
Sbjct: 220 KAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSH-FGSDLKDLLRNLLQV 278
Query: 564 NPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
+ R G + G +++ +F DW A+ QKKI PF P DTSNFD
Sbjct: 279 DLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFD 331
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 250 bits (639), Expect = 5e-66
Identities = 132/299 (44%), Positives = 191/299 (63%), Gaps = 8/299 (2%)
Query: 319 QYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
+Y DF++LR LG G+FG+V+ +R R YA+K L K IVK ++ HT ER +L
Sbjct: 82 KYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRML- 140
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
+ S PFI+ + +FQ +++V D++ GGELF L+K RF AKFY AE+ LA
Sbjct: 141 --SIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 198
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMD 498
LEYLH DI+YRDLKPENILLD NG+I + DFG +K + D T T CGT +Y+APE++
Sbjct: 199 LEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-VPDVTYTLCGTPDYIAPEVVST 257
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVK 558
+ Y K VD+WS GVLI+EM G++PF+ S+ K Y+ I ++KFP P+ + +K
Sbjct: 258 KP-YNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFP-PFFHPDAQDLLK 315
Query: 559 GLLNRNPKHRLGAIDDGRE-LRAHPFFNDIDWEAVRQKKIPPPFKPHL-ISETDTSNFD 615
L+ R+ RLG + +G E ++ HP+FN++ WE + + I P++P + + DTS FD
Sbjct: 316 KLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFD 374
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 249 bits (636), Expect = 1e-65
Identities = 150/459 (32%), Positives = 244/459 (52%), Gaps = 55/459 (11%)
Query: 234 RGSINPVWEHEATFDVLGTHSELDISI----YDAAQDDMFLGQVRLHPNMNAVTPGVHSE 289
R ++NP W TF + + + +S+ +D + F+G + + P S
Sbjct: 216 RSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPA--SG 273
Query: 290 WHKLKSRALGEHVT---------GDILIHWEYTSTKKRQYGPQ----------------- 323
W+KL ++ GE+ G++ + ++ K G +
Sbjct: 274 WYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDR 333
Query: 324 ----DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVR 379
DF L +LGKG+FG+V +K T +YA+K+L K V+++ +++ T+ E+ +L
Sbjct: 334 VKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLAL 393
Query: 380 TASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLAL 439
PF+ L FQT LY V ++++GG+L +H+Q+ G+F E +A FY AE+ + L
Sbjct: 394 L--DKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGL 451
Query: 440 EYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLM 497
+LH I+YRDLK +N++LD+ G+I + DFG+ K + D T TFCGT +Y+APE++
Sbjct: 452 FFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIA 511
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
+ Y K VD+W+ GVL++EM G PF D +++Q I V +P+ LS E S
Sbjct: 512 YQP-YGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS-LSKEAVSIC 569
Query: 558 KGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP 616
KGL+ ++P RLG +G R++R H FF IDWE + ++I PPFKP + + NFD
Sbjct: 570 KGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDK 628
Query: 617 EFTQTSTSFMNKQPIAATP----LSPAMQAKFVGFTFVD 651
FT+ QP+ P ++ Q+ F GF++V+
Sbjct: 629 FFTR-------GQPVLTPPDQLVIANIDQSDFEGFSYVN 660
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 248 bits (634), Expect = 2e-65
Identities = 133/313 (42%), Positives = 199/313 (63%), Gaps = 9/313 (2%)
Query: 304 GDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVK 363
GD L W + + FE LR LG G+FG+V VR ++T YAMK+L+K+ +VK
Sbjct: 25 GDFLYRWG--NPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVK 82
Query: 364 KNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRF 423
++ H + E+ IL + PF+V L+FSF+ + LYLV +++ GGE+F LQ+ GRF
Sbjct: 83 MKQVEHILNEKRIL---QAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRF 139
Query: 424 TEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNT 483
+E A FY A++VLA++YLH D+++RDLKPEN+L+D G + + DFG +K +K RT T
Sbjct: 140 SEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR-VKGRTWT 198
Query: 484 FCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVK 543
CGT EYLAPE+++ + GY K VD+W+LGVLI+EM G+ PF+A ++Y+KI G+V+
Sbjct: 199 LCGTPEYLAPEIILSK-GYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVR 257
Query: 544 FPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFK 602
FP LS + + ++ LL + R G + +G +++ H +F W A+ +KK+ PF
Sbjct: 258 FP-SKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFI 316
Query: 603 PHLISETDTSNFD 615
P D SNFD
Sbjct: 317 PKYTGPGDASNFD 329
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 246 bits (628), Expect = 9e-65
Identities = 130/306 (42%), Positives = 194/306 (62%), Gaps = 7/306 (2%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
E S + Y QDF+ L +G GTFG+V+ V++K +A+KV+S +++ + H
Sbjct: 35 EALSPEPPVYSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHV 94
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
E+++L S PF++ L +++ LY++ +++ GGELF +L+ GRF+ F
Sbjct: 95 HNEKSVLKEV---SHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLF 151
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEY 490
Y AE++ A+EYLH +IVYRDLKPENILLD +G+I L DFG +K L DRT T CGT EY
Sbjct: 152 YSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAK-KLVDRTWTLCGTPEY 210
Query: 491 LAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLS 550
LAPE++ + G+ + VD+W+LG+LIFEM G+ PFF + +YQKI GK+ FPR L
Sbjct: 211 LAPEVIQSK-GHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRH-LD 268
Query: 551 PEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET 609
+ +K LL + RLG + +G +++ H +F +DWEAV Q+K+ PP P + +
Sbjct: 269 FHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDG 328
Query: 610 DTSNFD 615
DTSNF+
Sbjct: 329 DTSNFE 334
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 246 bits (627), Expect = 1e-64
Identities = 140/352 (39%), Positives = 210/352 (58%), Gaps = 12/352 (3%)
Query: 270 LGQVRLHPNMNAVTPGVHSEWHKLKSRALGEHVTGDILIHWEYTSTK----KRQYGPQDF 325
+GQ N+N GV H L+ R + + K K +Y DF
Sbjct: 11 VGQTIQQQNVNTYGQGVLQPHHDLQQRQQQQQQRQHQQLLTSQLPQKSLVSKGKYTLHDF 70
Query: 326 EVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSS 385
+++R LG G+FG+V+ VR R YA+KVL K+ +VK ++ HT ER +L
Sbjct: 71 QIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLV---EH 127
Query: 386 PFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDN 445
PF++ + +FQ ++++V D++ GGELF L+K RF AKFY AE++LALEYLH +
Sbjct: 128 PFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAH 187
Query: 446 DIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYTKM 505
+I+YRDLKPENILLD NG+I + DFG +K +++ T T CGT +Y+APE++ + Y K
Sbjct: 188 NIIYRDLKPENILLDRNGHIKITDFGFAK-EVQTVTWTLCGTPDYIAPEVITTKP-YNKS 245
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNP 565
VD+WSLGVLI+EM G++PF+ + K Y+KI GKV +P P+ + L+ +
Sbjct: 246 VDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYP-PYFHPDVVDLLSKLITADL 304
Query: 566 KHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET-DTSNFD 615
R+G + G R+++AHP+F+++ WE + K I P++P + S DTS FD
Sbjct: 305 TRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFD 356
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 246 bits (627), Expect = 1e-64
Identities = 134/347 (38%), Positives = 215/347 (61%), Gaps = 28/347 (8%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G QDF+++R++G+G++ +V VR K +IYAMKV+ K+++ +I E+++ +
Sbjct: 248 GLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQA 307
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
+S +PF+VGL FQT + L+LV ++++GG+L +H+Q++ + E+ A+FY AE+ +AL
Sbjct: 308 SS--NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALN 365
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMD 498
+LH+ I+YRDLK +N+LLDA+G+I L D+G+ K L D T+TFCGT Y+APE+L
Sbjct: 366 FLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRG 425
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPF-FASDNQKM------YQKIAFGKVKFPRDVLSP 551
E Y VD+W+LGVL+FEM G SPF +DN M +Q I ++ PR LS
Sbjct: 426 EE-YGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPR-FLSV 483
Query: 552 EGRSFVKGLLNRNPKHRLGAIDDG--RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET 609
+ +KG LN++PK RLG ++++H FF IDW+ + +K+ PPF+P + +
Sbjct: 484 KASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDY 543
Query: 610 DTSNFDPEFTQTSTSFMNKQPIAATP-----LSPAMQAKFVGFTFVD 651
NFD +FT +P+ TP + Q++F GF +++
Sbjct: 544 GLDNFDTQFT--------SEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 246 bits (627), Expect = 1e-64
Identities = 134/347 (38%), Positives = 215/347 (61%), Gaps = 28/347 (8%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G QDF+++R++G+G++ +V VR K +IYAMKV+ K+++ +I E+++ +
Sbjct: 248 GLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQA 307
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
+S +PF+VGL FQT + L+LV ++++GG+L +H+Q++ + E+ A+FY AE+ +AL
Sbjct: 308 SS--NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALN 365
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMD 498
+LH+ I+YRDLK +N+LLDA+G+I L D+G+ K L D T+TFCGT Y+APE+L
Sbjct: 366 FLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRG 425
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPF-FASDNQKM------YQKIAFGKVKFPRDVLSP 551
E Y VD+W+LGVL+FEM G SPF +DN M +Q I ++ PR LS
Sbjct: 426 EE-YGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPR-FLSV 483
Query: 552 EGRSFVKGLLNRNPKHRLGAIDDG--RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET 609
+ +KG LN++PK RLG ++++H FF IDW+ + +K+ PPF+P + +
Sbjct: 484 KASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDY 543
Query: 610 DTSNFDPEFTQTSTSFMNKQPIAATP-----LSPAMQAKFVGFTFVD 651
NFD +FT +P+ TP + Q++F GF +++
Sbjct: 544 GLDNFDTQFT--------SEPVQLTPDDEDAIKRIDQSEFEGFEYIN 582
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 244 bits (623), Expect = 3e-64
Identities = 137/303 (45%), Positives = 183/303 (60%), Gaps = 7/303 (2%)
Query: 315 TKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGER 374
T K +YG QDF L+ LG G+FG+V+ V+ YA+KVL KK IV +I HT ER
Sbjct: 191 TTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDER 250
Query: 375 NILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAE 434
IL R PFI L +FQ +L++V DF GGELF L+K RF E AKFY AE
Sbjct: 251 YILSRV---QHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAE 307
Query: 435 LVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPE 494
++LAL+YLH N IVYRDLKPEN+LLD G++ + DFG +K T CGT +YLAPE
Sbjct: 308 VILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPE 367
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
++ + Y K D+WSLG+LIFEM G+ PF++ + K+Y+ I GKV +P SP
Sbjct: 368 IISLKP-YNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYP-SYFSPASI 425
Query: 555 SFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHL-ISETDTS 612
+ LL R+ R G + DG ++ HP+F DI W+ + +KI P+ P + D+S
Sbjct: 426 DLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSS 485
Query: 613 NFD 615
FD
Sbjct: 486 QFD 488
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 244 bits (622), Expect = 4e-64
Identities = 133/334 (39%), Positives = 203/334 (59%), Gaps = 12/334 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV---RT 380
DF L +LGKG+FG+V ++ + +YA+K+L K VIV+ +++ T+ E+ +L R
Sbjct: 350 DFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRG 409
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
F+ L +FQTP LY V ++++GG+L +H+Q+ G+F E A FY AE+ + L
Sbjct: 410 PGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLF 469
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMD 498
+LH+ I+YRDLK +N++LDA G+I + DFG+ K ++ T TFCGT +Y+APE++
Sbjct: 470 FLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAY 529
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVK 558
+ Y K VD+WS GVL++EM G PF D ++++Q I V +P+ LS E + K
Sbjct: 530 QP-YGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKS-LSREAVAICK 587
Query: 559 GLLNRNPKHRLGAIDDGR-ELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPE 617
G L ++P RLG+ DG +RAH FF IDWE + + +IPPPF+P + NFD
Sbjct: 588 GFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSG-ENFDKF 646
Query: 618 FTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVD 651
FT+ + + P L+ QA F GFT+V+
Sbjct: 647 FTRAAPAL---TPPDRLVLASIDQADFQGFTYVN 677
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 243 bits (620), Expect = 8e-64
Identities = 130/342 (38%), Positives = 210/342 (61%), Gaps = 10/342 (2%)
Query: 314 STKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGE 373
+ K+R+ +F +L++LGKG FG+V + K+T R+ A+KVL K I++ ++I E
Sbjct: 813 AAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAE 872
Query: 374 RNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIA 433
+ + + PF+ L SFQT +Y +F+ GG+L WH+Q + R + RAKFY A
Sbjct: 873 KKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYAA 931
Query: 434 ELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYL 491
E++LAL+Y HDN ++YRDLK ENILL G+I + D+GL K ++ +RT+TFCGT E++
Sbjct: 932 EVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFM 991
Query: 492 APELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSP 551
APE+L ++ YTK VD+W+ GVL+++M SPF D +++ I + +P D ++
Sbjct: 992 APEILKEQE-YTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPID-MAG 1049
Query: 552 EGRSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETD 610
E +GLL ++P+ RLGA D E+ PFF +I+++ + ++ PP+ P + S D
Sbjct: 1050 EIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPED 1109
Query: 611 TSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDE 652
TS F+ EFT + P+ + L+ + Q +F GF+F+ +
Sbjct: 1110 TSYFEQEFTSAPPTL---TPLPSV-LTTSQQEEFRGFSFMPD 1147
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 242 bits (617), Expect = 2e-63
Identities = 123/295 (41%), Positives = 193/295 (64%), Gaps = 8/295 (2%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
++F++LR LG G+FG+V+ +R + R YAMKVL K+++V+ ++ HT ER +L +
Sbjct: 85 KNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLML---SI 141
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
+ PFI+ + +FQ ++++ D++ GGELF L+K RF AKFY AE+ LALEYL
Sbjct: 142 VTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 201
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGY 502
H DI+YRDLKPENILLD NG+I + DFG +K + D T T CGT +Y+APE++ + Y
Sbjct: 202 HSKDIIYRDLKPENILLDKNGHIKITDFGFAKY-VPDVTYTLCGTPDYIAPEVVSTKP-Y 259
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN 562
K +D+WS G+LI+EM G++PF+ S+ K Y+KI +++FP + + + + L+
Sbjct: 260 NKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFP-PFFNEDVKDLLSRLIT 318
Query: 563 RNPKHRLGAIDDGRE-LRAHPFFNDIDWEAVRQKKIPPPFKPHL-ISETDTSNFD 615
R+ RLG + +G E ++ HP+F ++ WE + + I P++P + + DTS FD
Sbjct: 319 RDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFD 373
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 241 bits (616), Expect = 2e-63
Identities = 141/347 (40%), Positives = 211/347 (60%), Gaps = 26/347 (7%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRK---KDTMRIYAMKVLSK-KVIVKKNEIAHTIGERNILV 378
++F +LR+LGKG +G+V+ VRK KD IYAMKVL K +V+ K+ + HT+ ER +L
Sbjct: 15 ENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAERQVLE 74
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
R + +PF+V L ++FQT T L++V +++ GGELF HL G F + A+F IAELV+A
Sbjct: 75 RL--RGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELVVA 132
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK---DRTNTFCGTTEYLAPEL 495
++ LH ++YRDLK ENILLD G++ L DFGLSK L DR N++CGT EY++PE+
Sbjct: 133 IDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMSPEV 192
Query: 496 L-MDETGYTKMVDFWSLGVLIFEMCCGWSPFFA----SDNQKMYQKIAFGKVKFPRDVLS 550
+ E GY+ +VD+WSLGV+ FE+ G SPF + ++ + ++I KV FP+ +
Sbjct: 193 INRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPK-TMD 251
Query: 551 PEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETD 610
+ R F+ LL + + RLG + E++ H F + IDW+A ++ + P P + + D
Sbjct: 252 VDARDFIGQLLEKKLEKRLG-YNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRIGHDLD 310
Query: 611 TSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAK--FVGFTFVDESAI 655
T F EFT QP +P + A F G+++V S I
Sbjct: 311 TQFFSAEFT--------SQPPLYSPAESPLNANTLFRGYSYVSPSVI 349
Score = 121 bits (304), Expect = 3e-27
Identities = 104/351 (29%), Positives = 157/351 (44%), Gaps = 66/351 (18%)
Query: 330 LLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIV 389
LLGKG F V + + +A+K++S+K + +R + + P IV
Sbjct: 387 LLGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQ--------AQREARILEMVQGHPNIV 438
Query: 390 GLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVY 449
L P YLV + ++G EL ++K RFTE A + +LV A++YLHD IV+
Sbjct: 439 QLHDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVH 498
Query: 450 RDLKPENIL---LDANGNIALCDFGLSK-------ADLKD-----------------RTN 482
RDLKPENIL +D++ + L DFG ++ LK +
Sbjct: 499 RDLKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHNHSLHSE 558
Query: 483 TFCGTTEYLAPELL---MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQ----KMYQ 535
T C T +Y APE+L + Y + D WSLGV++F M G PF A Q ++ Q
Sbjct: 559 TPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQ 618
Query: 536 KIAFGKVKFPRDV---LSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAV 592
+I + F D +S + ++ + GLL +PK RL +EL AH W
Sbjct: 619 RICRAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRLSM----QELTAHM------WLKS 668
Query: 593 RQKKIPPPFKPHLISETDTSNFDPEFTQTSTSFMNKQ-------PIAATPL 636
P P ++ S+ D F +T +F++ +AA PL
Sbjct: 669 SASMDTPLQTPSIL----PSSADETFNETLRAFLHANRDGFHLLDVAAAPL 715
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 241 bits (616), Expect = 2e-63
Identities = 145/436 (33%), Positives = 225/436 (51%), Gaps = 52/436 (11%)
Query: 234 RGSINPVWEHEATFDVLGTHSELDISI----YDAAQDDMFLGQVRLHPNMNAVTPGVHSE 289
R ++NP W T+ +L + +SI +D + F+G + ++ + S
Sbjct: 284 RATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSF--GISELMKEAASG 341
Query: 290 WHKLKSRALGEHVTGDILIHWEYTSTKKRQ------------------------------ 319
W+KL S GE +I ++ K R+
Sbjct: 342 WYKLLSAEEGEFYNINITPEYDEDMEKVRKKMNENFITRDNSSSKPKDPAAPRASTLPLG 401
Query: 320 ------YGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGE 373
DF L +LGKG+FG+V +K T ++A+KVL K VI++ +++ T+ E
Sbjct: 402 SSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTE 461
Query: 374 RNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIA 433
+ +L S F+V L FQT LY V +F++GG+L + +Q+ G+F E A FY A
Sbjct: 462 KRVLALPEKPS--FLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAA 519
Query: 434 ELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYL 491
E+ + L +LH I+YRDLK +N++L+ +G+I + DFG+ K ++ T TFCGT +Y+
Sbjct: 520 EIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYI 579
Query: 492 APELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSP 551
APE+++ + Y K VD+W+ GVL+FEM G PF D +++ I V +P+ LS
Sbjct: 580 APEIILYQP-YGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKS-LSK 637
Query: 552 EGRSFVKGLLNRNPKHRLGAIDD----GRELRAHPFFNDIDWEAVRQKKIPPPFKPHLIS 607
E S K LL +NP RLG D R+++ HPFF IDW + ++I PPFKP L +
Sbjct: 638 EAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKT 697
Query: 608 ETDTSNFDPEFTQTST 623
+ T NFD F + T
Sbjct: 698 DRSTENFDHSFLKLPT 713
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 241 bits (615), Expect = 3e-63
Identities = 123/307 (40%), Positives = 192/307 (62%), Gaps = 10/307 (3%)
Query: 318 RQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNIL 377
+++ F +L++LGKG+FG+V V K YAMK L K VI++ ++ T ER +L
Sbjct: 231 KKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVL 290
Query: 378 VRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVL 437
+ + PF+ L SFQT L+ V ++++GG+L H+Q+ +F E R +FY E+V+
Sbjct: 291 I--LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVV 348
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL---KDRTNTFCGTTEYLAPE 494
AL++LH N+I+YRDLK +N+LLD +G+I L DFG++K ++ +TFCGT +Y++PE
Sbjct: 349 ALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPE 408
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
++ + Y + VDFWS GVL++EM G SPF +++ I + FP+ +S E
Sbjct: 409 IIKGQL-YNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPK-TISKEAA 466
Query: 555 SFVKGLLNRNPKHRLGAID--DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
+ L +RNP RLG + DG +R H FF +DW+ +++PPPFKP++ S +D S
Sbjct: 467 KCLSALFDRNPNTRLGMPECPDG-PIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDAS 525
Query: 613 NFDPEFT 619
NFD +FT
Sbjct: 526 NFDDDFT 532
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 241 bits (615), Expect = 3e-63
Identities = 123/307 (40%), Positives = 192/307 (62%), Gaps = 10/307 (3%)
Query: 318 RQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNIL 377
+++ F +L++LGKG+FG+V V K YAMK L K VI++ ++ T ER +L
Sbjct: 368 KKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVL 427
Query: 378 VRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVL 437
+ + PF+ L SFQT L+ V ++++GG+L H+Q+ +F E R +FY E+V+
Sbjct: 428 I--LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVV 485
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADL---KDRTNTFCGTTEYLAPE 494
AL++LH N+I+YRDLK +N+LLD +G+I L DFG++K ++ +TFCGT +Y++PE
Sbjct: 486 ALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPE 545
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
++ + Y + VDFWS GVL++EM G SPF +++ I + FP+ +S E
Sbjct: 546 IIKGQL-YNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPK-TISKEAA 603
Query: 555 SFVKGLLNRNPKHRLGAID--DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
+ L +RNP RLG + DG +R H FF +DW+ +++PPPFKP++ S +D S
Sbjct: 604 KCLSALFDRNPNTRLGMPECPDG-PIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDAS 662
Query: 613 NFDPEFT 619
NFD +FT
Sbjct: 663 NFDDDFT 669
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 241 bits (614), Expect = 4e-63
Identities = 150/469 (31%), Positives = 237/469 (49%), Gaps = 45/469 (9%)
Query: 223 DKLGNNQLNLK--RGSINPVWEHEATFDVLGTHSE----LDISIYDAAQDDMFLGQVRLH 276
D+ G + K + ++NPV+ TF++ + +++ +D + F+G
Sbjct: 238 DRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSF- 296
Query: 277 PNMNAVTPGVHSEWHKLKSRALGEHVT-------------GDILIHWEYTSTKKRQYGPQ 323
++ + W+K S+ GEH D + H + K+R
Sbjct: 297 -SLEELQKEPVDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDEVRHDRRPNEKRRMDNKD 355
Query: 324 --------------DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAH 369
DF ++++GKG+FG+V ++ T +YA+KVL K VI++ +++
Sbjct: 356 MPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMEL 415
Query: 370 TIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAK 429
+ E+ IL S PF+V + FQT L+ V ++ GG+L +H+Q+ GRF E A
Sbjct: 416 PMNEKKILA--LSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAI 473
Query: 430 FYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGT 487
FY E+ +AL +LH+ DI+YRDLK +NILLD G++ L DFGLSK + +R T TFCGT
Sbjct: 474 FYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGT 533
Query: 488 TEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRD 547
Y+APE++ + Y+ D+WS GVL+FE G +PF D +++ I K FP+
Sbjct: 534 PNYMAPEIVSYDP-YSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKH 592
Query: 548 VLSPEGRSFVKGLLNRNPKHRLGAIDDGR-ELRAHPFFNDIDWEAVRQKKIPPPFKPHLI 606
S E + L + P +RLGA R E+ HPFF ++DW+ ++ PP KP +
Sbjct: 593 -FSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIK 651
Query: 607 SETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAI 655
D SNFD FT+ T + L Q F+GF+F++ I
Sbjct: 652 HRKDISNFDDAFTKEKTDLTPTDKLFMMNLD---QNDFIGFSFMNPEFI 697
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 240 bits (613), Expect = 5e-63
Identities = 129/347 (37%), Positives = 206/347 (59%), Gaps = 12/347 (3%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
E + ++ G +F +++LGKG+FG+V K +YA+KVL K VI++ +++ T
Sbjct: 394 EVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCT 453
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
+ E+ IL ++ P++ L FQT L+ V ++++GG+L + +Q+ +F E R++F
Sbjct: 454 MTEKRILA--LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRF 511
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTT 488
Y AE+ AL +LH + ++YRDLK +NILLDA G+ L DFG+ K + + T TFCGT
Sbjct: 512 YAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTP 571
Query: 489 EYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV 548
+Y+APE+L E Y VD+W+LGVL++EM G PF A + +++ I V +P
Sbjct: 572 DYIAPEIL-QELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP-VW 629
Query: 549 LSPEGRSFVKGLLNRNPKHRLGAI--DDGRE-LRAHPFFNDIDWEAVRQKKIPPPFKPHL 605
LS E S +K + +NP RLG + +G + ++ HPFF +IDW + QKKI PPFKP +
Sbjct: 630 LSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRI 689
Query: 606 ISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDE 652
++ D +NFD +FT+ ++ Q +F GF++ E
Sbjct: 690 KTKRDVNNFDQDFTREEPVLTLVDEAIVKQIN---QEEFKGFSYFGE 733
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 239 bits (611), Expect = 8e-63
Identities = 129/304 (42%), Positives = 196/304 (64%), Gaps = 15/304 (4%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKK---DTMRIYAMKVLSK-KVIVKKNEIAHTIGERNIL 377
P+DFE L+L+G+G +G+V+QVRK+ D IYAMKV++K KV + ++ H ER IL
Sbjct: 20 PKDFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKIL 79
Query: 378 VRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVL 437
+ +SPF+ L ++FQT LYLV +F+ GGEL+ L+++ + E+ A+FY++E++L
Sbjct: 80 ---ETINSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIIL 136
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPEL 495
A+E+LH +DIVYRDLKP+N++L+ G++ L DFGL K LK ++T TFCGT EY+APE+
Sbjct: 137 AIEHLHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFCGTHEYMAPEM 196
Query: 496 LMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRS 555
+ + G+ VD W+LG+L+++M G PF + I GKV+ P LS G+
Sbjct: 197 IR-KVGHDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLP-PKLSASGKD 254
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
+K ++ R+P R+ D ++ H FF +IDW+ + PPFKP L + D S+FD
Sbjct: 255 LIKRIIKRDPTLRITIPD----IKEHEFFEEIDWDKLMAHDFEPPFKPTLANLEDVSHFD 310
Query: 616 PEFT 619
FT
Sbjct: 311 ESFT 314
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 239 bits (609), Expect = 1e-62
Identities = 128/336 (38%), Positives = 201/336 (59%), Gaps = 21/336 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF L +LGKG+FG+V +K T +YA+K+L K V+++ +++ T+ E+ +L
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+ L FQT LY V ++++GG+L +H+Q+ GRF E A FY AE+ + L +L
Sbjct: 401 --PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLMDETG 501
I+YRDLK +N++LD+ G+I + DFG+ K ++ D T TFCGT +Y+APE++ +
Sbjct: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP- 517
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y K VD+W+ GVL++EM G +PF D +++Q I V +P+ +S E + KGL+
Sbjct: 518 YGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS-MSKEAVAICKGLM 576
Query: 562 NRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
++P RLG +G R+++ H FF IDWE + +K+I PP+KP + NFD FT
Sbjct: 577 TKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGR-NAENFDRFFT- 634
Query: 621 TSTSFMNKQPIAATPLSPAM-----QAKFVGFTFVD 651
+ P TP + Q++F GF+FV+
Sbjct: 635 -------RHPPVLTPPDQEVIRNIDQSEFEGFSFVN 663
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 239 bits (609), Expect = 1e-62
Identities = 128/336 (38%), Positives = 201/336 (59%), Gaps = 21/336 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF L +LGKG+FG+V +K T +YA+K+L K V+++ +++ T+ E+ +L
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+ L FQT LY V ++++GG+L +H+Q+ GRF E A FY AE+ + L +L
Sbjct: 401 --PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLMDETG 501
I+YRDLK +N++LD+ G+I + DFG+ K ++ D T TFCGT +Y+APE++ +
Sbjct: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP- 517
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y K VD+W+ GVL++EM G +PF D +++Q I V +P+ +S E + KGL+
Sbjct: 518 YGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS-MSKEAVAICKGLM 576
Query: 562 NRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
++P RLG +G R+++ H FF IDWE + +K+I PP+KP + NFD FT
Sbjct: 577 TKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGR-NAENFDRFFT- 634
Query: 621 TSTSFMNKQPIAATPLSPAM-----QAKFVGFTFVD 651
+ P TP + Q++F GF+FV+
Sbjct: 635 -------RHPPVLTPPDQEVIRNIDQSEFEGFSFVN 663
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 238 bits (608), Expect = 2e-62
Identities = 128/349 (36%), Positives = 205/349 (58%), Gaps = 31/349 (8%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+DF + ++LGKG+FG+V+ K T + +A+K L K V++ +++ T+ E+ +L + +
Sbjct: 378 EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVL--SLA 435
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
PF+ + +FQT +L+ V ++++GG+L +H+Q +F RA FY AE++L L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDET 500
H IVYRDLK +NILLD +G+I + DFG+ K ++ +TNTFCGT +Y+APE+L+ +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
Y VD+WS GVL++EM G SPF D ++++ I +PR L E + + L
Sbjct: 556 -YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPR-WLEKEAKDLLVKL 613
Query: 561 LNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
R P+ RLG D +R HP F +I+WE + +K+I PPF+P + S D SNFD E
Sbjct: 614 FVREPEKRLGVRGD---IRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKE--- 667
Query: 621 TSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNNRKFL 669
F+N++P +F D + I+ N + N F+
Sbjct: 668 ----FLNEKP---------------RLSFADRALINSMDQNMFRNFSFM 697
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 237 bits (604), Expect = 5e-62
Identities = 131/344 (38%), Positives = 210/344 (60%), Gaps = 24/344 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF +L ++G+G++ +V Q T +IYA+K++ K++ + +I E+++ A+
Sbjct: 252 DFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVF--EAAS 309
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+ PF+VGL FQT + L+ V +F+ GG+L +H+Q++ + E+ A+FY E++LAL +LH
Sbjct: 310 NYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLH 369
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLM-DET 500
I+YRDLK +N+L+DA G+I L D+G+ K ++K D T+TFCGT Y+APE+L DE
Sbjct: 370 SRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEY 429
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQK--------MYQKIAFGKVKFPRDVLSPE 552
G++ VD+W+LGVL+FEM G SPF Q ++Q I +++ PR LS
Sbjct: 430 GFS--VDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRS-LSVR 486
Query: 553 GRSFVKGLLNRNPKHRLGA---IDDG-RELRAHPFFND-IDWEAVRQKKIPPPFKPHLIS 607
+KG LN++P RLG I++G R+++ H FF IDWEA+ QK + PP+ P + S
Sbjct: 487 ASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVES 546
Query: 608 ETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVD 651
+ D ++FD +FT P + Q++F GF +V+
Sbjct: 547 DRDLTHFDHQFTDELPQLSPDNPDVIARID---QSEFDGFEYVN 587
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 233 bits (595), Expect = 6e-61
Identities = 132/336 (39%), Positives = 202/336 (59%), Gaps = 10/336 (2%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
KK + DF L +LGKG FG+V K + YA+KVL K+ I+K E+ E++
Sbjct: 563 KKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKH 622
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
+ + PF++ L SFQT T +Y V +++ GG+L H+Q++ +F+ RA+FY AE+
Sbjct: 623 VFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQ-QFSVKRARFYGAEV 681
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKAD--LKDRTNTFCGTTEYLAP 493
LAL+Y H+N I YRDLK +NILL +G+I + D+GL K + L + T+TFCGT E++AP
Sbjct: 682 CLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTSTFCGTPEFMAP 741
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
E+L+++ Y+K VD+W+ GVL+++M G SPF D ++++ I + FP + + +
Sbjct: 742 EILLEQQ-YSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPIN-MPADA 799
Query: 554 RSFVKGLLNRNPKHRLGA-IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
S ++GLL R+P RLG+ D E+ AHPFF I W+ + K P +KP + D +
Sbjct: 800 VSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKPLINDPRDLN 859
Query: 613 NFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFT 648
NFD EFT + P+ T L+ Q F GF+
Sbjct: 860 NFDEEFTSACPTL---TPV-NTVLTRQQQECFRGFS 891
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 233 bits (594), Expect = 8e-61
Identities = 133/337 (39%), Positives = 196/337 (57%), Gaps = 8/337 (2%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
QDF L +LG+G FG+V V+ K T + YA+K L K+ ++ ++EI E+ IL
Sbjct: 557 QDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGC 616
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
PF++ L FQT + VT+F+ GG+L + E F E +A+FY+A +VL L++L
Sbjct: 617 TGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIH-EDVFPEPQARFYVACVVLGLQFL 675
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDET 500
H+ I+YRDLK +N+LLDA G + + DFGL K + DRT+TFCGT E+LAPE+L E
Sbjct: 676 HEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQE- 734
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
YT+ VD+W+LGVL++EM G PF ++++ I +P LS +G F++ L
Sbjct: 735 AYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYP-GFLSVQGLEFIQKL 793
Query: 561 LNRNPKHRLGAID-DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFT 619
L + P+ RLGA + D E++ PFF +W+A+ + I PPF P L D F+ EFT
Sbjct: 794 LQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFT 853
Query: 620 QTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAID 656
+ P + L+ QA F F FV E ++
Sbjct: 854 GLPPAL--TPPAPHSLLTARQQAAFRDFDFVSERFLE 888
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 233 bits (594), Expect = 8e-61
Identities = 131/332 (39%), Positives = 193/332 (57%), Gaps = 8/332 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
+F +L +LG+G FG+V + + + YA+K L K I+ ++E+ + E+ I +
Sbjct: 262 NFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAM 321
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V L FQT + V ++ +GG+L H+ + F E RA FY A +VL L+YLH
Sbjct: 322 RHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDV-FLEPRAVFYAACVVLGLQYLH 380
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDETG 501
+N I+YRDLK +N+LLD G + + DFGL K + DRT TFCGT E+LAPE+L ET
Sbjct: 381 ENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVL-TETS 439
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
YT+ VD+W LGVLIFEM G SPF D ++++ I +V++PR LS E + ++ LL
Sbjct: 440 YTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPR-FLSLEAIAVMRRLL 498
Query: 562 NRNPKHRLGAID-DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
+NP+ RLG+ + D +++ FF I W+ + +K+ PPF P + D SNFD EFT
Sbjct: 499 RKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTS 558
Query: 621 TSTSFMNKQPIAATPLSPAMQAKFVGFTFVDE 652
P L+ Q F F++ E
Sbjct: 559 EKAQL--TPPKEPRHLTEEEQLLFQDFSYTAE 588
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 233 bits (594), Expect = 8e-61
Identities = 131/332 (39%), Positives = 193/332 (57%), Gaps = 8/332 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
+F +L +LG+G FG+V + + + YA+K L K I+ ++E+ + E+ I +
Sbjct: 956 NFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAM 1015
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V L FQT + V ++ +GG+L H+ + F E RA FY A +VL L+YLH
Sbjct: 1016 RHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDV-FLEPRAVFYAACVVLGLQYLH 1074
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDETG 501
+N I+YRDLK +N+LLD G + + DFGL K + DRT TFCGT E+LAPE+L ET
Sbjct: 1075 ENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVL-TETS 1133
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
YT+ VD+W LGVLIFEM G SPF D ++++ I +V++PR LS E + ++ LL
Sbjct: 1134 YTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPR-FLSLEAIAVMRRLL 1192
Query: 562 NRNPKHRLGAID-DGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
+NP+ RLG+ + D +++ FF I W+ + +K+ PPF P + D SNFD EFT
Sbjct: 1193 RKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTS 1252
Query: 621 TSTSFMNKQPIAATPLSPAMQAKFVGFTFVDE 652
P L+ Q F F++ E
Sbjct: 1253 EKAQL--TPPKEPRHLTEEEQLLFQDFSYTAE 1282
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 231 bits (590), Expect = 2e-60
Identities = 123/327 (37%), Positives = 198/327 (59%), Gaps = 16/327 (4%)
Query: 329 RLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFI 388
++LGKG+FG+V K +A+K L K V++ +++ T+ E+ +L T + +PF+
Sbjct: 353 KVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVL--TLAAENPFL 410
Query: 389 VGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIV 448
L +FQT L+ V +F++GG+L +H+Q +GRF RA FY AE++ L++LH I+
Sbjct: 411 THLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGII 470
Query: 449 YRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDETGYTKMV 506
YRDLK +N+LLD +G+I + DFG+ K ++ + R +TFCGT +Y+APE+L YT V
Sbjct: 471 YRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQG-LKYTFSV 529
Query: 507 DFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPK 566
D+WS GVL++EM G SPF D ++++ I +PR ++ E + ++ L R P
Sbjct: 530 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPR-WITKESKDILEKLFEREPT 588
Query: 567 HRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEF--TQTSTS 624
RLG + ++ HPFF I+W + ++++ PPF+P + S D SNFD EF + S
Sbjct: 589 KRLGVTGN---IKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLS 645
Query: 625 FMNKQPIAATPLSPAMQAKFVGFTFVD 651
+ +K I + Q+ F GF+FV+
Sbjct: 646 YSDKNLIDSMD-----QSAFAGFSFVN 667
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 229 bits (584), Expect = 1e-59
Identities = 123/327 (37%), Positives = 197/327 (59%), Gaps = 16/327 (4%)
Query: 329 RLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFI 388
++LGKG+FG+V K A+K L K V++ +++ T+ E+ +L T + +PF+
Sbjct: 353 KVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRVL--TLAAENPFL 410
Query: 389 VGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIV 448
L +FQT L+ V +F++GG+L +H+Q +GRF RA FY AE++ L++LH I+
Sbjct: 411 THLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGII 470
Query: 449 YRDLKPENILLDANGNIALCDFGLSKADL--KDRTNTFCGTTEYLAPELLMDETGYTKMV 506
YRDLK +N+LLD +G+I + DFG+ K ++ + R +TFCGT +Y+APE+L YT V
Sbjct: 471 YRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQG-LKYTFSV 529
Query: 507 DFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPK 566
D+WS GVL++EM G SPF D ++++ I +PR ++ E + ++ L R P
Sbjct: 530 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPR-WITKESKDILEKLFEREPT 588
Query: 567 HRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEF--TQTSTS 624
RLG + ++ HPFF I+W + ++++ PPF+P + S D SNFD EF + S
Sbjct: 589 KRLGMTGN---IKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLS 645
Query: 625 FMNKQPIAATPLSPAMQAKFVGFTFVD 651
+ +K I + Q+ F GF+FV+
Sbjct: 646 YSDKNLIDSMD-----QSAFAGFSFVN 667
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 227 bits (579), Expect = 4e-59
Identities = 140/367 (38%), Positives = 204/367 (55%), Gaps = 37/367 (10%)
Query: 306 ILIHWEYTSTKKRQYGPQ------DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSK- 358
+ H ++ S+K Y P DF+ L +LG+G++G+V V++K+T R++A K L K
Sbjct: 66 VAAHGDFISSKGDNYVPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKA 125
Query: 359 KVIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQ 418
++++ + T ER IL PFI L ++FQ LYL+ + GGELF HL
Sbjct: 126 SIVLRAKGLEQTKNERQILEEVRH---PFICRLYYAFQDHDRLYLILQYAPGGELFSHLA 182
Query: 419 KEGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK-ADL 477
++ ED FY AEL LAL +LH IVYRDLKPEN LLDA G+I L DFGLSK A+
Sbjct: 183 EQRMLPEDVVAFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAEN 242
Query: 478 KDRTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKI 537
+F GT EY APE+L+++ Y VD+WS+G+LIF++ G PF A++++++ +KI
Sbjct: 243 GADCRSFVGTEEYCAPEILLEQP-YDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKI 301
Query: 538 AFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRE-----LRAHPFFNDIDWEAV 592
K P V S + R + L +NPK RLGA DG E ++ H + IDW +
Sbjct: 302 TRAKPNIPFYVTS-DARDIINKFLKKNPKQRLGA--DGPEKGYDAIKKHRIYRRIDWNKL 358
Query: 593 RQKKIPPPFKPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPL---------SPAMQAK 643
++ +PPP P + + NF EFT K P++ TP+ + +
Sbjct: 359 EKRMLPPPIVPCITNPEAAENFSVEFT--------KLPLSTTPILHEEFGNLTIGSHSSA 410
Query: 644 FVGFTFV 650
F GFT+V
Sbjct: 411 FQGFTYV 417
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 221 bits (564), Expect = 2e-57
Identities = 130/307 (42%), Positives = 181/307 (58%), Gaps = 29/307 (9%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
PQ FE +RLLG+G G+VY +R++DT +I+A+KVL+K ++K+ +I + E+ IL A
Sbjct: 321 PQSFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEIL---A 377
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQ--KEGRFTEDRAKFYIAELVLAL 439
+ PFIV L SFQT LYL ++ GGE F LQ K E+ AKFY +E+V AL
Sbjct: 378 TSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAAL 437
Query: 440 EYLHDNDIVYRDLKPENILLDANGNIALCDFGLS-------KADLKD------------- 479
EYLH +YRDLKPENILL +G++ L DF LS K +KD
Sbjct: 438 EYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGF 497
Query: 480 RTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAF 539
RTN+F GT EYLAPE++ G+T VD+W+LG+LI+EM G +PF ++ + + I
Sbjct: 498 RTNSFVGTEEYLAPEVIRG-NGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILT 556
Query: 540 GKVKFPRD-VLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIP 598
VKFP D +S + +K LLN+N RLG+ +++ HPFF + W +R +
Sbjct: 557 KDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQ--D 614
Query: 599 PPFKPHL 605
PP P L
Sbjct: 615 PPLIPAL 621
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 221 bits (563), Expect = 3e-57
Identities = 125/332 (37%), Positives = 194/332 (57%), Gaps = 10/332 (3%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+ F ++ +LG+G FG+V + T YA+KVL K I+ ++E+ + E+ I ++
Sbjct: 688 EQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSR 747
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
PF+V L FQT ++ ++ GG+L H+ + F E R FY A +VL L++L
Sbjct: 748 ARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIH-DDVFDEVRGCFYAACVVLGLDFL 806
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLMDET 500
H ++I+YRD+K +N+LLD G + + DFGL K ++ D+T+TFCGT E+LAPE+L D +
Sbjct: 807 HKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSD-S 865
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
YT+ +D+W LGVLIFEM G PF D ++++ I V++PR LS E + ++ L
Sbjct: 866 SYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPR-YLSVESIAIMRRL 924
Query: 561 LNRNPKHRLGAID-DGRELRAHPFFNDIDWE--AVRQKKIPPPFKPHLISETDTSNFDPE 617
L + P+ RLG + D +++ FF I WE + ++I PPF+P + + D SNFD E
Sbjct: 925 LRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLE 984
Query: 618 FTQTSTSFMNKQPIAATPLSPAMQAKFVGFTF 649
FTQ F + P++ A Q F F F
Sbjct: 985 FTQEKARF--SAASSTRPITEADQRLFNNFDF 1014
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 218 bits (555), Expect = 3e-56
Identities = 139/355 (39%), Positives = 203/355 (57%), Gaps = 44/355 (12%)
Query: 305 DILIHWEYTSTK--KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIV 362
D+L H T K + DFE+++ + +G FG+V+ RK+ T +A+KVL K ++
Sbjct: 648 DVLEHASATPQLLLKDRISIDDFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMI 707
Query: 363 KKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGR 422
+KN+I + ERNIL+ PF+V +SF +LYLV ++++GG+L+ LQK G
Sbjct: 708 RKNDIERILQERNILITVRY---PFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGC 764
Query: 423 FTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK-------- 474
E+ A+ YIAELVLALEYLH IV+RDLKP+N+L+ NG+I L DFGLSK
Sbjct: 765 LDEEIARIYIAELVLALEYLHSLKIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGLINNTI 824
Query: 475 ------ADLKDRTNTF---------------CGTTEYLAPELLM-DETGYTKMVDFWSLG 512
+D+ RTN+ GT +YLAPE+L+ E GY D+WS G
Sbjct: 825 DLSGHESDVSPRTNSHHFQKNQEEERIRHSAVGTPDYLAPEILLGTEHGYA--ADWWSAG 882
Query: 513 VLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV---LSPEGRSFVKGLLNRNPKHRL 569
+++FE+ G PF AS +K++ I GK+ +P DV +S E + + LL P+ RL
Sbjct: 883 IVLFELLTGIPPFTASRPEKIFDNILNGKMPWP-DVPGEMSYEAQDLINRLLVHEPEKRL 941
Query: 570 GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTSTS 624
GA + E+++HPFF +DWE + +K F P S DTS F F+++S S
Sbjct: 942 GA-NGAAEVKSHPFFQGVDWENLALQK--AAFVPQPESINDTSYFVSRFSESSCS 993
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 216 bits (549), Expect = 1e-55
Identities = 119/309 (38%), Positives = 181/309 (58%), Gaps = 8/309 (2%)
Query: 309 HWEYTSTKKRQ-YGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEI 367
H + + T R+ + E + +GKGTFG+V R K T YA+KVL+ + +V +
Sbjct: 46 HMKLSITPTRESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQT 105
Query: 368 AHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDR 427
H E+ +L++ PFIV + S + LY++ +F+ GGE+F +L+ F+
Sbjct: 106 QHVHNEKRVLLQL---KHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSM 162
Query: 428 AKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGT 487
A+FY +E+V ALEY+H IVYRDLKPEN++L G+I + DFG +K +L+DRT T CGT
Sbjct: 163 ARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK-ELRDRTYTICGT 221
Query: 488 TEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRD 547
+YLAPE L TG+ K VD+W+LG+LI+EM G PF ++Y I K+KFPR
Sbjct: 222 PDYLAPESLA-RTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRS 280
Query: 548 VLSPEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLI 606
+ + VK LL + R+G + +G ++++ H +F ++W+ ++ PP P L
Sbjct: 281 -FNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLY 339
Query: 607 SETDTSNFD 615
DT NFD
Sbjct: 340 HPGDTGNFD 348
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 216 bits (549), Expect = 1e-55
Identities = 123/306 (40%), Positives = 180/306 (58%), Gaps = 9/306 (2%)
Query: 313 TSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIG 372
T+T G D+E+ LG G+FG+V VR++++ YA K LSK IVK +++H +
Sbjct: 35 TNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMS 94
Query: 373 ERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYI 432
E+N+L S + P V L S++ LYLV + GGELF + +K +FTE +A+FY
Sbjct: 95 EKNVL---RSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYA 151
Query: 433 AELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLA 492
A++ LALEYLH ++YRDLKPENI++D NG + + DFG +K ++ RT T CGT EYL
Sbjct: 152 AQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAK-KVETRTMTLCGTPEYLP 210
Query: 493 PELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFA--SDNQKMYQKIAFGKVKFPRDVLS 550
PE++ + Y VD+W+ GVL+FE G SPF A D MY KI K P S
Sbjct: 211 PEIIQSKP-YGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMP-SYFS 268
Query: 551 PEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET 609
R V LL + R G + +G R+++ H +F D++W + + + P+ P++ +
Sbjct: 269 GALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPE 328
Query: 610 DTSNFD 615
D SNFD
Sbjct: 329 DISNFD 334
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 215 bits (547), Expect = 2e-55
Identities = 128/311 (41%), Positives = 181/311 (58%), Gaps = 32/311 (10%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
GPQ FE +RLLG+G G+V+ VR+K T R+YA+KVLSK ++K+N+I + E+ IL
Sbjct: 492 GPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEIL--- 548
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQ--KEGRFTEDRAKFYIAELVLA 438
A+ + PFIV L SFQ+ LYL ++ GGE F LQ K ED A+FY +E+ A
Sbjct: 549 ATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAA 608
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS---------------KADLKD---- 479
LEYLH +YRDLKPENILL +G+I L DF LS ++ L D
Sbjct: 609 LEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKIC 668
Query: 480 ----RTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQ 535
RTN+F GT EY+APE++ G+T VD+W+LG+LI+EM G++PF + + +
Sbjct: 669 SDGFRTNSFVGTEEYIAPEVIRG-NGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFT 727
Query: 536 KIAFGKVKFP-RDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQ 594
I +V FP + +S + +K LL +N RLG +++ HPFF + W +R
Sbjct: 728 NILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRN 787
Query: 595 KKIPPPFKPHL 605
++ PP P L
Sbjct: 788 QE--PPLIPVL 796
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 214 bits (545), Expect = 4e-55
Identities = 118/306 (38%), Positives = 178/306 (57%), Gaps = 10/306 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF V R++G+G FG+VY RK+DT ++YAMK L KK I K + ER +L ++
Sbjct: 190 DFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG 249
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PFIV + ++F TP L + D M+GG+L +HL + G F+E +FY AE++L LE++H
Sbjct: 250 DCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMH 309
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYT 503
+ +VYRDLKP NILLD +G++ + D GL+ K + + GT Y+APE+L Y
Sbjct: 310 NRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYD 369
Query: 504 KMVDFWSLGVLIFEMCCGWSPF---FASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
D++SLG ++F++ G SPF D ++ + V+ P D SPE S ++GL
Sbjct: 370 SSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELP-DSFSPELHSLLEGL 428
Query: 561 LNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKP-----HLISETDTSNF 614
L R+ RLG + G +E++ PFF +DW+ V ++ PPP P + D +F
Sbjct: 429 LQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIPPRGEVNAADAFDIGSF 488
Query: 615 DPEFTQ 620
D E T+
Sbjct: 489 DEEDTK 494
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 214 bits (545), Expect = 4e-55
Identities = 130/399 (32%), Positives = 213/399 (52%), Gaps = 58/399 (14%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EY ++++ G DFE+L ++G+G FG+V ++K T +YAMK L K ++++ ++ H
Sbjct: 106 EYMRLQRQKMGVDDFELLSIIGRGAFGEVRICKEKSTGSVYAMKKLKKSEMLRRGQVEHV 165
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L A SPFIV L +SFQ LYL+ +++ GG++ L ++ ED +F
Sbjct: 166 KAERNVL---AEVDSPFIVKLCYSFQDDEHLYLIMEYLPGGDMMTLLMRKDTLREDETRF 222
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS-----------KADLKD 479
Y+A+ +LA+E +H ++ V+RD+KP+N+L+ NG+I L DFGLS KA+L D
Sbjct: 223 YVAQTILAIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLSKSLESKNFPDFKAELVD 282
Query: 480 RTN------------------------------------TFCGTTEYLAPELLMDETGYT 503
R+ + GT +Y+APE+L+ + GY
Sbjct: 283 RSTKPAAEHDRLSKPPSAPRRTQQEQLLHWQQNRRTLAFSTVGTPDYIAPEVLL-KKGYG 341
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEGRSFVKGL 560
D+WSLG ++FEM G+ PF++ + +KI K +KFP + LS E + ++ L
Sbjct: 342 MECDWWSLGAIMFEMLVGFPPFYSEEPLATCRKIVNWKTCLKFPDEAKLSIEVKDLIRRL 401
Query: 561 LNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
L N + RLG E++AHP+F ++WE + + P+ P + E DT NF+
Sbjct: 402 L-CNVEQRLGT-KGVHEIKAHPWFRGVEWERLYESN--APYIPQVKHELDTQNFEKFDEV 457
Query: 621 TSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHY 659
ST + + + + A F+G+TF + +DEH+
Sbjct: 458 PSTCQTSSKSSPWRKMISSKDANFLGYTFKNLEIVDEHH 496
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 212 bits (540), Expect = 1e-54
Identities = 118/306 (38%), Positives = 176/306 (56%), Gaps = 10/306 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
+F V R++G+G FG+VY RK DT ++YAMK L KK I K + ER +L ++
Sbjct: 190 EFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG 249
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PFIV + ++F TP L + D M+GG+L +HL + G F+E +FY E++L LE++H
Sbjct: 250 DCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHVH 309
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYT 503
+ +VYRDLKP NILLD +G+ + D GL+ K + + GT Y+APE+L T Y
Sbjct: 310 NRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYD 369
Query: 504 KMVDFWSLGVLIFEMCCGWSPF---FASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
D++SLG ++F++ G SPF D ++ + V+ P D SPE +S ++GL
Sbjct: 370 SSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELP-DTFSPELKSLLEGL 428
Query: 561 LNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKP-----HLISETDTSNF 614
L R+ RLG G +E++ H FF +DW+ V +K PPP P + D +F
Sbjct: 429 LQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSF 488
Query: 615 DPEFTQ 620
D E T+
Sbjct: 489 DEEDTK 494
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 212 bits (540), Expect = 1e-54
Identities = 115/304 (37%), Positives = 177/304 (57%), Gaps = 10/304 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNIL-VRTAS 382
DF V R++G+G FG+VY RK DT ++YAMK L KK I K + ER +L + +
Sbjct: 190 DFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG 249
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
+ PFIV + ++FQ+P L + D M+GG+L +HL + G FTE FY +E++L LE++
Sbjct: 250 QDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILGLEHM 309
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGY 502
H+ +VYRDLKP NILLD NG++ + D GL+ K + + GT Y+APE+L Y
Sbjct: 310 HNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHASVGTHGYMAPEVLAKGVAY 369
Query: 503 TKMVDFWSLGVLIFEMCCGWSPF---FASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
D++SLG +++++ G SPF + D ++ + ++ P + LS + R ++G
Sbjct: 370 DSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNEGLSKDCRDLLEG 429
Query: 560 LLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKP-----HLISETDTSN 613
LL R+ RLG G E++ HPFF D+DW+ V +++ PP P + D N
Sbjct: 430 LLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAADAFDIGN 489
Query: 614 FDPE 617
FD +
Sbjct: 490 FDDD 493
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 208 bits (529), Expect = 3e-53
Identities = 130/383 (33%), Positives = 206/383 (52%), Gaps = 57/383 (14%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
E+ K+ + G +DFE L+++G+G FG+V V+KKDT +YAMK+L K +++K ++ H
Sbjct: 75 EFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHI 134
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER+ILV S ++V + +SFQ +LYL+ +F+ GG++ L K+ TE+ +F
Sbjct: 135 RAERDILVEA---DSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQF 191
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF------ 484
YIAE VLA++ +H ++RD+KP+N+LLD+ G++ L DFGL K F
Sbjct: 192 YIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNH 251
Query: 485 -------------------------------CGTTEYLAPELLMDETGYTKMVDFWSLGV 513
GT +Y+APE+ M +TGY K+ D+WSLGV
Sbjct: 252 SLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFM-QTGYNKLCDWWSLGV 310
Query: 514 LIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDVLSPEGRSFVKGLLNR---NPKHR 568
+++EM G+ PF + Q+ Y+K+ K + FP +V E K L+ R +HR
Sbjct: 311 IMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEK---AKDLILRFCCEWEHR 367
Query: 569 LGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTSTSFMNK 628
+GA E++++ FF +DWE +R++ P + S DTSNFD EF ++
Sbjct: 368 IGA-PGVEEIKSNSFFEGVDWEHIRER--PAAISIEIKSIDDTSNFD-EFPESDI----L 419
Query: 629 QPIAATPLSPAMQAKFVGFTFVD 651
+P AT P K + F++
Sbjct: 420 KPTVATSNHPETDYKNKDWVFIN 442
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 208 bits (529), Expect = 3e-53
Identities = 123/347 (35%), Positives = 192/347 (54%), Gaps = 52/347 (14%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
E+ K+ + G DFE L+++G+G FG+V V+KKDT IYAMK+L K +++K ++AH
Sbjct: 76 EFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHI 135
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER+ILV ++V + +SFQ +LYL+ +F+ GG++ L K+ TE+ +F
Sbjct: 136 RAERDILVEA---DGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQF 192
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF------ 484
YI+E VLA++ +H ++RD+KP+N+LLDA G++ L DFGL K F
Sbjct: 193 YISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTH 252
Query: 485 -------------------------------CGTTEYLAPELLMDETGYTKMVDFWSLGV 513
GT +Y+APE+ M +TGY K+ D+WSLGV
Sbjct: 253 NPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFM-QTGYNKLCDWWSLGV 311
Query: 514 LIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDVLSPEGRSFVKGLLNR---NPKHR 568
+++EM G+ PF + Q+ Y+K+ K + FP +V E K L+ R + ++R
Sbjct: 312 IMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEK---AKDLILRFCIDSENR 368
Query: 569 LGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
+G E++ HPFF +DWE +R++ P + + S DTSNFD
Sbjct: 369 IGN-SGVEEIKGHPFFEGVDWEHIRERPAAIPIE--IKSIDDTSNFD 412
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 207 bits (526), Expect = 6e-53
Identities = 114/318 (35%), Positives = 180/318 (55%), Gaps = 26/318 (8%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
K+ +DFE ++L+ G +G V+ VR K T + +AMK ++K+ ++ +N+I ER+I
Sbjct: 504 KKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDI 563
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L +PF+V + SF T L +V +++ GG+ L+ G D + Y AE V
Sbjct: 564 LTFA---ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF------------ 484
LALEYLH+ IV+RDLKP+N+L+ + G+I L DFGLSK L T
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREF 680
Query: 485 -----CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAF 539
CGT EY+APE+++ + GY K VD+W++G++++E G PFF ++++ ++
Sbjct: 681 LDKQVCGTPEYIAPEVILRQ-GYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVIS 739
Query: 540 GKVKFPR--DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKI 597
++ +P + L P+ + LL++NP RLG E++ HPFF +DW + ++K
Sbjct: 740 DEIVWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQK- 797
Query: 598 PPPFKPHLISETDTSNFD 615
F P L SE DTS FD
Sbjct: 798 -AEFIPQLESEDDTSYFD 814
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 207 bits (526), Expect = 6e-53
Identities = 111/312 (35%), Positives = 179/312 (56%), Gaps = 26/312 (8%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF+ +RL+ G +G VY VR ++T + +A+K ++K+ ++ +N++ ER+IL
Sbjct: 357 DFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMA--- 413
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+PF+V SF+T L ++ +++ GG+ L+ G + + Y+AE +LA+EYLH
Sbjct: 414 DNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLH 473
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT------------------NTFC 485
IV+RDLKP+N+L+ A G+I L DFGLSK L +RT C
Sbjct: 474 SYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLC 533
Query: 486 GTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFP 545
GT EY+APE+++ GY K VD+W+LG++++E G PFF + ++ K+ V++P
Sbjct: 534 GTPEYIAPEVIL-RRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYP 592
Query: 546 R--DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKP 603
+ L PE + LL +NP RLG ++ +L AH FF +D+ ++ ++K F P
Sbjct: 593 EEDEALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTSLLRQK--AEFVP 650
Query: 604 HLISETDTSNFD 615
L +E DTS FD
Sbjct: 651 QLDNEEDTSYFD 662
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 206 bits (525), Expect = 8e-53
Identities = 150/472 (31%), Positives = 237/472 (49%), Gaps = 67/472 (14%)
Query: 227 NNQLNLKRGSINPVWEHEATFDVLGTHSELDISIYDAAQDDMF-LGQVRLHPNMNAVTPG 285
N+ L+ +R NP ++T D + + Y A D Q R++ T
Sbjct: 4 NDYLHFER---NPSLFPKSTLDKVQKTKKYIEHYYKVAVDHAVERNQRRINLEQRLATER 60
Query: 286 VHSEWHKLKSRALGEHVTGDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKK 345
E + RA GE + ++ ++ + +DF ++++GKG FG+V V+K
Sbjct: 61 GSEERKNRQLRASGEKES-------QFLRFRRTRLSLEDFSTIKVIGKGAFGEVRLVQKL 113
Query: 346 DTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVT 405
DT +IYAMK L K + K++++AH ER++LV + SP++V L ++FQ LYL+
Sbjct: 114 DTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVES---DSPWVVSLYYAFQDSLYLYLIM 170
Query: 406 DFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNI 465
+F+ GG+L L F+ED +FY+AE VLA+ +H ++RD+KP+NIL+D +G+I
Sbjct: 171 EFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNILIDRDGHI 230
Query: 466 ALCDFGLS----KAD-----LKDRTN---------------------------------- 482
L DFGLS K D +K RT
Sbjct: 231 KLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDAIWLTMSSKDKMATWKKNRRVMAY 290
Query: 483 TFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK- 541
+ GT +Y+APE+ + + GY + D+WSLG ++FE GW PF + ++ + Y+KI +
Sbjct: 291 STVGTPDYIAPEIFLQQ-GYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRE 349
Query: 542 -VKFPRDV-LSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPP 599
+ FP D+ LS E R + L+ + +HRLG E+ HPFF IDW+ +R+
Sbjct: 350 TLTFPNDIHLSIEARDLMDRLMT-DSEHRLGR-GGAIEIMQHPFFTGIDWDHIRE--TAA 405
Query: 600 PFKPHLISETDTSNFD-PEFTQTSTSFMNKQPIAATPLS-PAMQAKFVGFTF 649
PF P+L S TDT F E Q + +QP + P + F+G+T+
Sbjct: 406 PFIPNLKSITDTHYFPVDELEQVPEQPVTQQPASVDPQTLEQTNLAFLGYTY 457
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 205 bits (521), Expect = 2e-52
Identities = 114/309 (36%), Positives = 181/309 (57%), Gaps = 40/309 (12%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+DFE+++ + +G FG+V+ +K+ T ++A+KVL K +++KN + + ERNIL+ S
Sbjct: 752 EDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAERNILI---S 808
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
+PF+V +SF +LYLV ++++GG+LF L+ G ED A+ YIAE+VLALEYL
Sbjct: 809 VRNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALEYL 868
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCG---------------- 486
H +I++RDLKP+N+L++ +G+I L DFGLSK L + T+ G
Sbjct: 869 HSVNIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAEDGSK 928
Query: 487 -----------------TTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASD 529
T +YLAPE+L+ G+ K D+WS+GV++FE+ G PF A
Sbjct: 929 AQHSQGKDSRKKHAVVGTPDYLAPEILLG-MGHGKTADWWSVGVILFEVLVGIPPFNAET 987
Query: 530 NQKMYQKIAFGKVKFPR--DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDI 587
Q++++ I + +P + +S E + LL NP RLGA G E++ H FF DI
Sbjct: 988 PQQIFENIINRDIPWPNVPEEISYEAHDLINKLLTENPVQRLGATGAG-EVKQHHFFKDI 1046
Query: 588 DWEAVRQKK 596
+W+ + ++K
Sbjct: 1047 NWDTLARQK 1055
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 203 bits (517), Expect = 7e-52
Identities = 112/318 (35%), Positives = 182/318 (57%), Gaps = 26/318 (8%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
+R+ DFE ++L+ G +G VY VR K++ + +AMK ++K+ ++ +N+I ER+I
Sbjct: 31 RRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDI 90
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L +PF+V + SF+T L +V +++ GG+ ++ G D A+ Y AE V
Sbjct: 91 LTFA---ENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETV 147
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF------------ 484
LALEYLH+ IV+RDLKP+N+L+ + G+I L DFGLSK L T
Sbjct: 148 LALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREF 207
Query: 485 -----CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAF 539
CGT EY+APE+++ + GY K VD+W++G++++E G PFF ++++ ++
Sbjct: 208 LDKQVCGTPEYIAPEVILRQ-GYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVIS 266
Query: 540 GKVKFPR--DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKI 597
++ +P + P+ + + LL +NP RLG E++ H FF +DW ++ ++K
Sbjct: 267 DEINWPEKDEAPPPDAQDLITLLLRQNPLERLGT-GGAYEVKQHRFFRSLDWNSLLRQK- 324
Query: 598 PPPFKPHLISETDTSNFD 615
F P L SE DTS FD
Sbjct: 325 -AEFIPQLESEDDTSYFD 341
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 203 bits (517), Expect = 7e-52
Identities = 121/355 (34%), Positives = 197/355 (55%), Gaps = 51/355 (14%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EY K+ + G +DFE L+++G+G FG+V V+KKDT +YAMKVL K +++K ++AH
Sbjct: 79 EYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHV 138
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER++LV + ++V + +SFQ P +LYL+ +F+ GG++ L K+ +E+ +F
Sbjct: 139 RAERDVLVEADHQ---WVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQF 195
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL------------------ 472
YI+E LA++ +H ++RD+KP+N+LLDA G++ L DFGL
Sbjct: 196 YISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQ 255
Query: 473 -----------SKADLKDRTNTF-----------CGTTEYLAPELLMDETGYTKMVDFWS 510
S D K R ++ GT +Y+APE+ + +TGY D+WS
Sbjct: 256 AKPSDFIGTCASPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFL-QTGYGPACDWWS 314
Query: 511 LGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEGRSFVKGLLNRNPKH 567
LGV+++EM G+ PF + + Q Y+K+ + + FP ++ +S E + + +
Sbjct: 315 LGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADR- 373
Query: 568 RLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTS 622
RLG+ +L++ PFF +DWE +R++ P + I DTSNFD EF S
Sbjct: 374 RLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSID--DTSNFD-EFPDVS 425
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 203 bits (516), Expect = 9e-52
Identities = 128/330 (38%), Positives = 178/330 (53%), Gaps = 41/330 (12%)
Query: 319 QYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
+ GP FE + LLGKG G+VY VR+K + + YAMKVLSK+ ++K+N+ E++IL
Sbjct: 189 EVGPSSFEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHIL- 247
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKE-GR-FTEDRAKFYIAELV 436
A+ + PFIV L SFQ+ LYL ++ GGE F LQ+ GR +E+ AKFYIAE+
Sbjct: 248 --ATSNHPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVT 305
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK---------------------- 474
ALEYLH +YRDLKPENILL +G+I L DF LSK
Sbjct: 306 AALEYLHLMGFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNA 365
Query: 475 --ADLKD-----RTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFA 527
D K RTN+F GT EY+APE++ G+T VD+W+LG+L +EM +PF
Sbjct: 366 YALDTKSCIADFRTNSFVGTEEYIAPEVIKG-CGHTSAVDWWTLGILFYEMLYATTPFKG 424
Query: 528 SDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN----RNPKHRLGAIDDGRELRAHPF 583
+ + I V FP +P S K L+ ++ RLG+ +++ HPF
Sbjct: 425 KNRNMTFSNILHKDVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAADVKLHPF 484
Query: 584 FNDIDWEAVRQKKIPPPFKPHLISETDTSN 613
F ++ W +R + PP P L + N
Sbjct: 485 FKNVQWALLRHTE--PPIIPKLAPIDEKGN 512
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 202 bits (515), Expect = 1e-51
Identities = 127/356 (35%), Positives = 198/356 (54%), Gaps = 19/356 (5%)
Query: 313 TSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIG 372
+ K+ + +DFE+L+++G+G FG+V V+ K+ +++AMK+L+K ++K+ E A
Sbjct: 65 SKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFRE 124
Query: 373 ERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQK-EGRFTEDRAKFY 431
ER++LV +K +I L ++FQ +LYLV D+ GG+L L K E R ED A+FY
Sbjct: 125 ERDVLVNGDNK---WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 432 IAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT---NTFCGTT 488
+AE+V+A++ +H V+RD+KP+NIL+D NG+I L DFG ++D T + GT
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 489 EYLAPELLM---DETG-YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF 544
+Y++PE+L D G Y D+WSLGV ++EM G +PF+A + Y KI K +F
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 545 PRDVLSPEGRSFVKGLLNR---NPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPF 601
+ K L+ R + +HRLG + + + HPFF+ IDW+ +R P+
Sbjct: 302 QFPAQVTDVSENAKDLIRRLICSREHRLGQ-NGIEDFKKHPFFSGIDWDNIR--NCEAPY 358
Query: 602 KPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDE 657
P + S TDTSNFD + S P FVGFT+ + +
Sbjct: 359 IPEVSSPTDTSNFDVDDDCLKNS--ETMPPPTHTAFSGHHLPFVGFTYTSSCVLSD 412
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 201 bits (512), Expect = 3e-51
Identities = 129/379 (34%), Positives = 202/379 (53%), Gaps = 49/379 (12%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
+Y K+ + DFE L+++G+G FG+V V+K DT IYAMK+L K +V+K + AH
Sbjct: 66 DYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHV 125
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER+IL + ++V + +SFQ ++LYLV +F+ GG++ L K+ TE+ +F
Sbjct: 126 RAERDIL---SEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQF 182
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL------------------ 472
YIAE LA++++H ++RD+KP+N+LLDA G++ L DFGL
Sbjct: 183 YIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWPS 242
Query: 473 --------------SKADLKDRTN-----TFCGTTEYLAPELLMDETGYTKMVDFWSLGV 513
KA+ R + GT +Y+APE + GYTK D+WSLGV
Sbjct: 243 TLPPDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPE-VFQPNGYTKSCDWWSLGV 301
Query: 514 LIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEGRSFVKGLLNRNPKHRLG 570
+++EM G+ PF + Q+ Y+K+ + + FP DV +S E ++ +K + RLG
Sbjct: 302 IMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFC-CEAERRLG 360
Query: 571 AIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTSTSFMNKQP 630
E++ PF IDW +R++ PPP + + S DTSNFD +F ++
Sbjct: 361 NHGGLDEIKQCPFVKRIDWNHIRER--PPPIRVTVKSIDDTSNFD-DFPDEDLTWPTSTL 417
Query: 631 IAATPLSPAMQAKFVGFTF 649
I P + +FV FT+
Sbjct: 418 IRPEE-QPGRRGEFVDFTY 435
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 201 bits (512), Expect = 3e-51
Identities = 126/393 (32%), Positives = 211/393 (53%), Gaps = 54/393 (13%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EY ++ + G DF++L ++GKG FG+V R+K T ++YAMK L K ++++ ++ H
Sbjct: 110 EYMRLQRHKLGVADFDLLTMIGKGAFGEVRVCREKTTGQVYAMKKLKKAEMLRRGQVEHV 169
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L A S +IV L SFQ LYLV +++ GG++ L ++ TE+ AKF
Sbjct: 170 RAERNLL---AEVDSNYIVKLYCSFQDDDHLYLVMEYLPGGDMMTLLMRKDTLTEEEAKF 226
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA---------DLKDRT 481
Y+AE VLA+E +H ++ ++RD+KP+N+LLD G++ L DFGL K D + +
Sbjct: 227 YVAETVLAIESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSAIGENDFSNNS 286
Query: 482 N--------------------------------TFCGTTEYLAPELLMDETGYTKMVDFW 509
N + GT +Y+APE+L+ + GY D+W
Sbjct: 287 NGSTEQEAGSTAPKRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVLL-KKGYGMECDWW 345
Query: 510 SLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRD-VLSPEGRSFVKGLLNRNPK 566
SLG +++EM G+ PF++ D +KI K +KFP + +LS E + + LL + +
Sbjct: 346 SLGAIMYEMLVGYPPFYSDDPMSTCRKIVNWKSHLKFPEEAILSREAKDLINSLL-CSVR 404
Query: 567 HRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP-EFTQTSTSF 625
RLG+ EL+AH +F +DW+ + + F P + + DT NF+ + +++ T
Sbjct: 405 RRLGS-KGADELKAHTWFETVDWDTIFD--MDAAFVPEVNDDLDTQNFEKFDESESETQT 461
Query: 626 MNKQPIAATPLSPAMQAKFVGFTFVDESAIDEH 658
+K LS + FVG+T+ + ++++
Sbjct: 462 SSKSGPWRKMLS-SKDINFVGYTYKNFEIVNDY 493
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 201 bits (511), Expect = 3e-51
Identities = 116/325 (35%), Positives = 181/325 (55%), Gaps = 36/325 (11%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DFEV++ + +G FG V RK T ++A+KVL K +++KN + + ER+IL+ +
Sbjct: 827 DFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDILINARN- 885
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V +SF +LYLV ++++GG+ + L+K G E A+ YIAE+VLALEYLH
Sbjct: 886 --PFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIAEVVLALEYLH 943
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTN--------------------- 482
+V+RDLKP+N+L+ +G++ L DFGLSK L + T+
Sbjct: 944 SEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPKLP 1003
Query: 483 ------TFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQK 536
+ GT +YLAPE+L+ TG+ D+WS+G++++E G PF A Q+++
Sbjct: 1004 TLDHKRSAVGTPDYLAPEILLG-TGHGATADWWSVGIILYEFLVGIPPFNADHPQQIFDN 1062
Query: 537 IAFGKVKFP--RDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQ 594
I +++P + +S E R + LL +P RLGA E++ H FF DIDW + Q
Sbjct: 1063 ILNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQRLGA-RGAAEVKQHSFFKDIDWNTLAQ 1121
Query: 595 KKIPPPFKPHLISETDTSNFDPEFT 619
+K F P + DTS F ++
Sbjct: 1122 QK--AAFVPDSENAFDTSYFQSRYS 1144
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 201 bits (511), Expect = 3e-51
Identities = 114/325 (35%), Positives = 183/325 (56%), Gaps = 28/325 (8%)
Query: 313 TSTKKRQYGPQ--DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
T + +Q PQ DF++++L+ G +G VY V+ K T + +AMK ++K ++ +N++
Sbjct: 821 TGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQV 880
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER+IL + +PF+V + SF+T L LV +++ GG+ L+ G D A+F
Sbjct: 881 FAERDIL---SFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARF 937
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD-RTNTF----- 484
Y AE VLA+EYLH IV+RDLKP+N+L+ A G+I L DFGLSK L TN +
Sbjct: 938 YFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYID 997
Query: 485 -----------CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKM 533
GT EY+APE+++ + GY K VD+WS+G++++E G PFF +++
Sbjct: 998 SETRQFSDKQVYGTPEYIAPEVILRQ-GYGKPVDWWSMGIILYEFLIGCVPFFGETTEEL 1056
Query: 534 YQKIAFGKVKFPRD---VLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWE 590
+ +++P + E + + LL +NP+ RLG E++ H +F +DW
Sbjct: 1057 FAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWN 1116
Query: 591 AVRQKKIPPPFKPHLISETDTSNFD 615
++ ++K F P L + DTS FD
Sbjct: 1117 SLLRQK--AEFVPQLSHDDDTSYFD 1139
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 199 bits (506), Expect = 1e-50
Identities = 114/318 (35%), Positives = 182/318 (56%), Gaps = 26/318 (8%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
+R+ DFE ++L+ G +G VY VR +DT + +A+K ++K+ ++ +N+I ER+I
Sbjct: 189 RRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDI 248
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L +PF+V + SF+T L +V +++ GG+ L+ G D A+ Y AE V
Sbjct: 249 LTFA---ENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETV 305
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD-RTNTF----------- 484
LALEYLH+ IV+RDLKP+N+L+ + G+I L DFGLSK L TN +
Sbjct: 306 LALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREF 365
Query: 485 -----CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAF 539
CGT EY+APE++ + GY K VD+W++GV+++E G PFF ++++ ++
Sbjct: 366 IDKQVCGTPEYIAPEVIFRQ-GYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVS 424
Query: 540 GKVKFPR--DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKI 597
++ +P + L + + + LL ++P RLG E++ HPFF +DW + + K
Sbjct: 425 DEIMWPEGDEALPADAQDLITRLLRQSPLDRLGT-GGTHEVKQHPFFLALDWAGLLRHK- 482
Query: 598 PPPFKPHLISETDTSNFD 615
F P L +E DTS FD
Sbjct: 483 -AEFVPQLEAEDDTSYFD 499
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 199 bits (506), Expect = 1e-50
Identities = 103/236 (43%), Positives = 153/236 (64%), Gaps = 5/236 (2%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
E S + Y QD + L +G GTFG+V+ V++K +A+KV+S ++++ + H
Sbjct: 35 EARSPEAPAYRLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHV 94
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
E+++L S PF++ L +++ LY++ +++ GGELF +L+ G F+ F
Sbjct: 95 HNEKSVLKEV---SHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLF 151
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEY 490
Y AE++ A+EYLH +IVYRDLKPENILLD +G+I L DFG +K L DRT T CGT EY
Sbjct: 152 YSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAK-KLVDRTWTLCGTPEY 210
Query: 491 LAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR 546
LAPE++ + G+ + VD+W+LG+LIFEM G+ PFF + +YQKI GK+ FPR
Sbjct: 211 LAPEVIQSK-GHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPR 265
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 199 bits (505), Expect = 2e-50
Identities = 113/297 (38%), Positives = 171/297 (57%), Gaps = 10/297 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVR-KKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
DF ++ LG G FG+V V+ K + + +AMK+L K+ IV + H E+ I+
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIM---QG 430
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
S FIV L +F+ LY++ + GGEL+ L+ G F + +FY A +V A YL
Sbjct: 431 AHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRTNTFCGTTEYLAPELLMDETG 501
H I+YRDLKPEN++LD G L DFG + K +T TFCGT EY+APE+++++ G
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNK-G 549
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFG--KVKFPRDVLSPEGRSFVKG 559
+ D+WSLG+L++E+ G PF D K Y I G ++FP+ + + + +K
Sbjct: 550 HDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKI-AKNAANLIKK 608
Query: 560 LLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
L NP RLG + +G ++++ H +F +WE +R+ + PP P + S TDTSNFD
Sbjct: 609 LCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFD 665
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 198 bits (504), Expect = 2e-50
Identities = 129/360 (35%), Positives = 192/360 (52%), Gaps = 23/360 (6%)
Query: 313 TSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIG 372
+ KK + DFEVL+++GKG FG+V VR + IYAMK+L+K +VK+ E A
Sbjct: 71 SKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFRE 130
Query: 373 ERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQK-EGRFTEDRAKFY 431
ER++LV + +I L ++FQ +LY V D+ GG++ L K E AKFY
Sbjct: 131 ERDVLVYGDRR---WITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFY 187
Query: 432 IAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD---RTNTFCGTT 488
IAE+VLA++ LH V+RD+KP+N+LLD G+I L DFG L D +N GT
Sbjct: 188 IAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTP 247
Query: 489 EYLAPELLM---DETG-YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--V 542
+Y++PE+L D G Y K D+WSLG+ ++EM G +PF++ Y KI + +
Sbjct: 248 DYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML 307
Query: 543 KFPRD----VLSPEGRSFVKGLL-NRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKI 597
FP D V+S E + ++ L+ + + + + D + HPFF IDW +R
Sbjct: 308 DFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSD---FQLHPFFEGIDWNTIRDSN- 363
Query: 598 PPPFKPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDE 657
PP+ P + S DTSNFD + + + QP FVGF++ S + +
Sbjct: 364 -PPYVPEVSSPEDTSNFDVDVCEDDFTPCETQPPRVLAAFTGNHLPFVGFSYTHGSLLSD 422
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 198 bits (504), Expect = 2e-50
Identities = 131/356 (36%), Positives = 206/356 (57%), Gaps = 25/356 (7%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
K+ Q +DFE+++++G+G FG+V V+ K+T RIYAMK+L+K ++K+ E A ER+
Sbjct: 67 KEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERD 126
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQK-EGRFTEDRAKFYIAE 434
+LV + +I L ++FQ LYLV D+ GG+L L K E + ED A+FYI E
Sbjct: 127 VLV---NGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGE 183
Query: 435 LVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD----RTNTFCGTTEY 490
+VLA++ +H V+RD+KP+N+LLD NG+I L DFG S + D +++ GT +Y
Sbjct: 184 MVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG-SCLKMNDDGTVQSSVAVGTPDY 242
Query: 491 LAPELLM---DETG-YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIA--FGKVKF 544
++PE+L D G Y D+WSLGV ++EM G +PF+A + Y KI + +F
Sbjct: 243 ISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQF 302
Query: 545 PRDV--LSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFK 602
P V +S E + ++ L+ + + RLG + + + H FF ++WE +R + P+
Sbjct: 303 PSHVTDVSEEAKDLIQRLI-CSRERRLGQ-NGIEDFKKHAFFEGLNWENIR--NLEAPYI 358
Query: 603 PHLISETDTSNFD-PEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDE 657
P + S +DTSNFD + +T + P + T S + F+GFTF ES +
Sbjct: 359 PDVSSPSDTSNFDVDDDVLRNTEIL--PPGSHTGFS-GLHLPFIGFTFTTESCFSD 411
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 198 bits (503), Expect = 3e-50
Identities = 130/390 (33%), Positives = 207/390 (52%), Gaps = 62/390 (15%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EY ++ + G DFE L ++GKG FG+V R+K T +YAMK L K ++++ ++ H
Sbjct: 106 EYMRRQRHKMGTDDFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRGQVEHV 165
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L A S IV L SFQ LYL+ +++ GG++ L ++ TED A+F
Sbjct: 166 KAERNLL---AEVDSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARF 222
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK---------------- 474
Y+ E VLA+E +H ++ ++RD+KP+N+LLD +G++ L DFGL K
Sbjct: 223 YVGETVLAIESIHKHNYIHRDIKPDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAH 282
Query: 475 -------------ADLKDRTN----------------TFCGTTEYLAPELLMDETGYTKM 505
A + R+ + GT +Y+APE+L+ + GY
Sbjct: 283 NLSGALQSDGRPVAPRRTRSQMEQLQNWQRNRRMLAYSTVGTPDYIAPEVLL-KKGYGME 341
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEGRSFVKGLLN 562
D+WSLG +++EM G+ PF++ + +KI K +KFP +V LSPE + + LL
Sbjct: 342 CDWWSLGAIMYEMLVGFPPFYSDEPMTTCRKIVNWKNYLKFPDEVRLSPEAKDLICRLL- 400
Query: 563 RNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTS 622
N + R+G E++ HP+F+ ++WE + Q K F P + E DT NF+ +F +
Sbjct: 401 CNVEQRIGT-KGANEIKEHPWFSGVEWEKLYQMK--AAFIPQVNDELDTQNFE-KFEEVK 456
Query: 623 TSFMNKQPIAATPLSPAMQAK---FVGFTF 649
T + K P + P + +K FVG+T+
Sbjct: 457 TK-IPKTP-KSGPWRKMLSSKDINFVGYTY 484
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 197 bits (502), Expect = 4e-50
Identities = 114/331 (34%), Positives = 183/331 (54%), Gaps = 42/331 (12%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DFE+++ + +G FG+V+ +K+ T ++A+KVL K +++KN + + ER+IL+ +
Sbjct: 889 DFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNAVESILAERDILINVRN- 947
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PF+V +SF +LYLV ++++GG+L+ L+ G ED + YIAE+VLALEYLH
Sbjct: 948 --PFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLALEYLH 1005
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFC------------------ 485
+V+RDLKP+N+L+ +G+I L DFGLSK L + T+
Sbjct: 1006 SEGVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLA 1065
Query: 486 ---------------GTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDN 530
GT +YLAPE+L+ TG+ D+WS+G+++FE+ G PF A
Sbjct: 1066 ASEEQLERRKKRSAVGTPDYLAPEILLG-TGHGATADWWSVGIILFELIVGIPPFNAEHP 1124
Query: 531 QKMYQKIAFGKVKFPR--DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDID 588
Q+++ I K+ +P + +S E + L +P RLGA E++ H FF DI+
Sbjct: 1125 QQIFDNILNRKIPWPHVPEEMSAEAHDIIDRFLTEDPHQRLGA-RGAAEVKQHIFFKDIN 1183
Query: 589 WEAVRQKKIPPPFKPHLISETDTSNFDPEFT 619
W+ + ++K F P S DTS F ++
Sbjct: 1184 WDTLARQK--AAFVPASESAIDTSYFRSRYS 1212
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 197 bits (500), Expect = 6e-50
Identities = 129/396 (32%), Positives = 208/396 (51%), Gaps = 60/396 (15%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EY ++ + G DFE L ++GKG FG+V R+K T +YAMK L K ++++ ++ H
Sbjct: 29 EYMRRQRHKMGADDFEPLTMIGKGAFGEVRICREKGTGNVYAMKKLKKSEMLRRGQVEHV 88
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L A S IV L SFQ LYL+ +++ GG++ L ++ TED A+F
Sbjct: 89 KAERNLL---AEVDSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARF 145
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK----ADLKDRTNTFC- 485
YI E VLA+E +H ++ ++RD+KP+N+LLD +G++ L DFGL K ++L+++ T
Sbjct: 146 YIGETVLAIESIHKHNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCSNLQEKDFTVAR 205
Query: 486 --------------------------------------GTTEYLAPELLMDETGYTKMVD 507
GT +Y+APE+L+ + GY D
Sbjct: 206 NVSGALQSDGRPVATRRTQQEQLLNWQRNRRMLAYSTVGTPDYIAPEVLL-KKGYGMECD 264
Query: 508 FWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEGRSFVKGLLNRN 564
+WSLG +++EM G+ PF++ D +KI + +KFP +V LSPE + + LL N
Sbjct: 265 WWSLGAIMYEMLVGFPPFYSDDPMTTCRKIVNWRNYLKFPDEVRLSPEAKDLICRLL-CN 323
Query: 565 PKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTSTS 624
+ RLG E++ HP+F +W + Q K F P + E DT NF+ +F +T
Sbjct: 324 VEQRLGT-KGADEIKGHPWFRGTEWGKLYQMK--AAFIPQVNDELDTQNFE-KFEETDKQ 379
Query: 625 FMNKQPIAATPLSPAMQAK---FVGFTFVDESAIDE 657
+ + P + +K FVG+T+ + +++
Sbjct: 380 V--PKSAKSGPWRKMLSSKDINFVGYTYKNVEIVND 413
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 197 bits (500), Expect = 6e-50
Identities = 129/398 (32%), Positives = 205/398 (51%), Gaps = 63/398 (15%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EY ++ + G DFE+L ++GKG FG+V VR+ +T ++AMK L K ++++ ++ H
Sbjct: 123 EYMRLQRHKMGADDFELLTMIGKGAFGEVRVVREINTGHVFAMKKLKKSEMLRRGQVEHV 182
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L A S IV L SFQ LYL+ +++ GG++ L ++ +ED AKF
Sbjct: 183 RAERNLL---AEVDSNCIVKLYCSFQDNEYLYLIMEYLPGGDMMTLLMRKDTLSEDEAKF 239
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK------ADLKDRT--- 481
YIAE VLA+E +H+ + ++RD+KP+N+LLD G++ L DFGL K D +D T
Sbjct: 240 YIAESVLAIESIHNRNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSVIDGEDFTVGN 299
Query: 482 ---------------------------------NTFCGTTEYLAPELLMDETGYTKMVDF 508
+ GT +Y+APE+L+ + GY D+
Sbjct: 300 AGSGGGSESVSTTPKRSQQEQLEHWQKNRRMLAYSTVGTPDYIAPEVLL-KKGYGMECDW 358
Query: 509 WSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDVLSPEGRSFVKGLLNRNPK 566
WSLG +++EM G+ PF+A D +KI K +KFP + G + G L +
Sbjct: 359 WSLGAIMYEMLVGYPPFYADDPMSTCRKIVNWKTHLKFPEESRLSRGARDLIGKLLCSVN 418
Query: 567 HRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSN---FDPEFTQTST 623
RLG+ +++AHP+F + WE + Q + F P + + DT N FD E QT
Sbjct: 419 QRLGS-TGASQIKAHPWFEGVQWEKIYQ--MEAAFIPEVNDDLDTQNFEKFDEEDNQT-- 473
Query: 624 SFMNKQPIAATPLSPAMQAK---FVGFTFVDESAIDEH 658
+ P P + +K FVG+T+ + ++++
Sbjct: 474 ----QAPSRTGPWRKMLSSKDINFVGYTYKNFEIVNDY 507
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 196 bits (499), Expect = 8e-50
Identities = 124/359 (34%), Positives = 199/359 (54%), Gaps = 22/359 (6%)
Query: 318 RQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNIL 377
R+ P+DF+ ++LG+G+F V R+ T R YA+K+L K+ I+K+N++ + ER+++
Sbjct: 75 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 134
Query: 378 VRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVL 437
R PF V L F+FQ LY + GEL +++K G F E +FY AE+V
Sbjct: 135 SRL---DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 191
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFG----LSKADLKDRTNTFCGTTEYLAP 493
ALEYLH I++RDLKPENILL+ + +I + DFG LS + R N+F GT +Y++P
Sbjct: 192 ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSP 251
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
ELL +++ K D W+LG +I+++ G PF A + ++QKI + FP + P+
Sbjct: 252 ELLTEKSA-CKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP-EKFFPKA 309
Query: 554 RSFVKGLLNRNPKHRLGA--IDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHL--ISET 609
R V+ LL + RLG ++ L+AHPFF + WE + Q + PP +L +SE
Sbjct: 310 RDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQ-QTPPKLTAYLPAMSED 368
Query: 610 DT---SNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNN 665
D N+D +Q ++++ S ++ A G S I+++ ++ +N
Sbjct: 369 DEDCYGNYDNLLSQ-----FGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSN 422
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 196 bits (499), Expect = 8e-50
Identities = 112/312 (35%), Positives = 176/312 (55%), Gaps = 19/312 (6%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
+ + DFE ++ G G++ +V + +KK+T +YA+K++ KK I K+N+ A+ ER +
Sbjct: 33 QENFTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIV 92
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
L + P I+ L F+FQ + LY+ + GGELF + ++GR +ED A+FY AE+V
Sbjct: 93 LDQL---EHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVV 149
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFG------------LSKADLKDRTNTF 484
ALEY+H +++RD+KPEN+LL ++G+I + DFG L A D+ TF
Sbjct: 150 DALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTF 209
Query: 485 CGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF 544
GT Y+ PE+L + + T D W+LG +++M G SPF + ++Q+I +KF
Sbjct: 210 VGTAAYVPPEVL-NSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKF 268
Query: 545 PRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGR-ELRAHPFFNDIDWEAVRQKKIPPPFKP 603
P S R + LL+ P R GA +G L+ HPFFN +DW+ +R + PP P
Sbjct: 269 PNH-FSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKNLR-SQTPPKLAP 326
Query: 604 HLISETDTSNFD 615
S+T + D
Sbjct: 327 DPASQTASPERD 338
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 196 bits (498), Expect = 1e-49
Identities = 130/363 (35%), Positives = 199/363 (54%), Gaps = 24/363 (6%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
+K + DF++L+++G+G FG+V V+ T ++YAMK+L+K ++K+ E A ER+
Sbjct: 91 RKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERD 150
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQK-EGRFTEDRAKFYIAE 434
+LV +I L ++FQ +LYLV D+ GG+L L K E + ED AKFYI E
Sbjct: 151 VLV---FGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITE 207
Query: 435 LVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT---NTFCGTTEYL 491
++LA+ +H V+RD+KP+N+LLD G++ L DFG KD T N GT +Y+
Sbjct: 208 MILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYI 267
Query: 492 APELLM---DETG-YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF--- 544
+PE+L D G Y D+WSLGV ++EM G +PF+A + Y KI + F
Sbjct: 268 SPEILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLP 327
Query: 545 PRDVLSPEGRSFVKGLLNR---NPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPF 601
++ L+ + + LL + P++RLG + ++ HP+F IDW+ +RQ P P+
Sbjct: 328 SQETLNYKVSETSQDLLCKLICIPENRLGQ-NGIQDFMDHPWFVGIDWKNIRQG--PAPY 384
Query: 602 KPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTF--VDESAIDEHY 659
P + S TDTSNFD + + P +A P F+GFTF S +D
Sbjct: 385 VPEVSSPTDTSNFDVD--DNDVRLTDSIPPSANPAFSGFHLPFIGFTFSLTSSSTLDSKK 442
Query: 660 NNA 662
N +
Sbjct: 443 NQS 445
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 195 bits (496), Expect = 2e-49
Identities = 120/347 (34%), Positives = 181/347 (51%), Gaps = 47/347 (13%)
Query: 313 TSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIG 372
T + + P FE +RLLG+G G+VY VR+K R++AMK+L+K+ ++K++++ +
Sbjct: 143 TKISRVEVTPHSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLA 202
Query: 373 ERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELF--WHLQKEGRFTEDRAKF 430
E+ IL ++ PFIV L SFQ+ LYL ++ +GGE F H + E A F
Sbjct: 203 EQEILTKS---KHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACF 259
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK---------------- 474
Y AE+ ALEYLH +YRDLKPENILL +G+I L DF LSK
Sbjct: 260 YAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHS 319
Query: 475 --------ADLKD-----RTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCG 521
D RTN+F GT EY+APE++ G+T VD+W+LG+ I+E+ G
Sbjct: 320 TFSQEKPALDTNSYFSNFRTNSFVGTEEYIAPEVIR-SCGHTVAVDWWTLGIFIYEILYG 378
Query: 522 WSPFFASDNQKMYQKIAFGKVKFPR----DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRE 577
+PF + + I + V FP +S +S ++ LL ++ R G++ +
Sbjct: 379 TTPFKGKNRHATFSNILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGASD 438
Query: 578 LRAHPFFNDIDWEAVRQKKIPPPFKPHL------ISETDTSNFDPEF 618
++ HPFF I W +R K PP P + + +D N + +F
Sbjct: 439 IKQHPFFRHIQWALLRSMK--PPIIPKIEDGMEAVEPSDNDNEEEDF 483
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 195 bits (496), Expect = 2e-49
Identities = 119/297 (40%), Positives = 179/297 (60%), Gaps = 12/297 (4%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+D + + LG G FG+V VR + R YA+K+++K IV+ + +H + ER IL++
Sbjct: 272 EDLQRVSTLGMGGFGRVELVRSASS-RTYALKIMNKAHIVETKQESHVVSERRILMQC-- 328
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
+ +IV + +++ +Y++ + GGE++ L+K+GRF D +FY A + ALEYL
Sbjct: 329 -DNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYL 387
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLMDET 500
H +IVYRDLKPEN+LLD NG L DFG +K LK+ RT TFCGT EY+APE+++++
Sbjct: 388 HRKNIVYRDLKPENMLLDRNGWPKLVDFGFAK-KLKNGGRTWTFCGTAEYVAPEIVLNK- 445
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFG--KVKFPRDVLSPEGRSFVK 558
G+ VD W+LG+ + E+ G PF ++D Y I G K +PR V + E +
Sbjct: 446 GHDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFV-TKEAIDMML 504
Query: 559 GLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
L P RLG D G E+R H +F++ D+ R +I PPF P + ++ DTSNFD
Sbjct: 505 SLCKYEPTERLGFGDIG-EIRHHIWFDNFDFVGFRAHRIRPPFIPSVANDIDTSNFD 560
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 194 bits (492), Expect = 5e-49
Identities = 115/307 (37%), Positives = 178/307 (57%), Gaps = 18/307 (5%)
Query: 308 IHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEI 367
+ W++ + G F R+LGKG FG+V + K T ++YA K L+KK + K+
Sbjct: 175 LQWKWLEAQPM--GEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGY 232
Query: 368 AHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHL----QKEGRF 423
+ E+ IL++ S+ FIV L ++F+T DL LV M+GG++ +H+ ++ F
Sbjct: 233 QGAMVEKKILMKVHSR---FIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGF 289
Query: 424 TEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS--KADLKDRT 481
E RA FY A+++ LE+LH IVYRDLKPEN+LLD +GN+ + D GL+ D + +T
Sbjct: 290 PEPRALFYTAQIICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKT 349
Query: 482 NTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFAS----DNQKMYQKI 537
+ GT ++APELL E Y VD+++LGV ++EM PF A +N+++ +I
Sbjct: 350 KGYAGTPGFMAPELLQGEE-YDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRI 408
Query: 538 AFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKK 596
VK+P D S + F + LL ++P+ RLG D+ +LRAHP F D++W +
Sbjct: 409 ISEPVKYP-DKFSQASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGM 467
Query: 597 IPPPFKP 603
+ PPF P
Sbjct: 468 LMPPFIP 474
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 194 bits (492), Expect = 5e-49
Identities = 114/283 (40%), Positives = 163/283 (57%), Gaps = 7/283 (2%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDT-MRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
QDFE ++++G G FG+V+ VR K + ++AMK+L I+++ E +IL R
Sbjct: 5 QDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRIY 64
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
PF+ L + + L+ +++ GGELF+ L+K GRF E A+FY AE++ AL +
Sbjct: 65 G--CPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRF 122
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETG 501
+H I+YRDLKPENIL+ + G+I L DFG S + + GT EY++PE L E
Sbjct: 123 IHGRGILYRDLKPENILITSTGHIKLIDFGFSVYE-SENIYMISGTPEYMSPEKLRSEDD 181
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
+ D+W LGV+I+EM CG PF+ S +Y KI V FP V SP R + GLL
Sbjct: 182 -GRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYV-SPVARCLITGLL 239
Query: 562 NRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPH 604
++N RLG E+ HPFF IDW V ++I PPF P+
Sbjct: 240 DKNRATRLGT-KGICEIMGHPFFKGIDWHEVESRRIEPPFIPN 281
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 193 bits (491), Expect = 7e-49
Identities = 114/321 (35%), Positives = 177/321 (54%), Gaps = 22/321 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DFE+ ++ G G++ +V + +KKD +YA+K++ KK I K+N+ A+ ER +L +
Sbjct: 41 DFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQL--- 97
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
P IV L F+FQ LY+ + GGELF + ++GR +ED A+FY AE+V ALEY+H
Sbjct: 98 EHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALEYIH 157
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFG------------LSKADLKDRTNTFCGTTEYL 491
+ +++RD+KPEN+LL +G+I + DFG L A D+ TF GT Y+
Sbjct: 158 NMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYV 217
Query: 492 APELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSP 551
PE+L + + T D W+LG +++M G SPF + ++Q+I +KFP S
Sbjct: 218 PPEVL-NSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNH-FSE 275
Query: 552 EGRSFVKGLLNRNPKHRLGAIDDGRE-LRAHPFFNDIDWEAVRQ----KKIPPPFKPHLI 606
R + LL+ +P R GA +G + L+ HPFF +DW+ +R K P P
Sbjct: 276 AARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWKNLRSQTPPKLAPDPASQSAS 335
Query: 607 SETDTSNFDPEFTQTSTSFMN 627
E D S ++P ++ N
Sbjct: 336 PERDGSPWNPTHVGDTSVLQN 356
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 193 bits (490), Expect = 9e-49
Identities = 112/297 (37%), Positives = 169/297 (56%), Gaps = 9/297 (3%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
Q+ E++ LG G FG+V V+ K+ +AMK + KK IV + H E+ IL S
Sbjct: 451 QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS 510
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
PFIV L +F+ +Y++ + GGEL+ L+ G F E +KF +A + A +YL
Sbjct: 511 ---PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYL 567
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRTNTFCGTTEYLAPELLMDETG 501
H I+YRDLKPEN++LDA G + L DFG + K +T TFCGT EY+APE+++++ G
Sbjct: 568 HRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNK-G 626
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFG--KVKFPRDVLSPEGRSFVKG 559
+ VDFWSLG+L++E+ G PF D Y I G K+ FPR + + ++
Sbjct: 627 HDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKI-TRRPEDLIRR 685
Query: 560 LLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
L +NP RLG + +G +++ H + N +WE ++ + +P P + L D S FD
Sbjct: 686 LCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFD 742
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 191 bits (484), Expect = 4e-48
Identities = 114/293 (38%), Positives = 166/293 (55%), Gaps = 9/293 (3%)
Query: 328 LRLLGKGTFGQVYQVRKK-DTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSP 386
L LG G FG+V V D + +A+K L KK IV + H ERNI++ T S+
Sbjct: 429 LATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMET---STD 485
Query: 387 FIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDND 446
+IV L +F+ +Y++ + GGEL+ L+ G F + A+FY+A ++ LEYLH +
Sbjct: 486 WIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKN 545
Query: 447 IVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPELLMDETGYTKM 505
IVYRDLKPEN LL G + L DFG +K R T TFCGT EY++PE+++++ G+ +
Sbjct: 546 IVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNK-GHDQA 604
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFG--KVKFPRDVLSPEGRSFVKGLLNR 563
D+W+LG+ I E+ G PF ASD K Y I G ++ P + + VK L
Sbjct: 605 ADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRD 664
Query: 564 NPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
NP RLG+ G ++R H +F DWE +R + + PP P + + D +NFD
Sbjct: 665 NPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFD 717
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 191 bits (484), Expect = 4e-48
Identities = 114/293 (38%), Positives = 166/293 (55%), Gaps = 9/293 (3%)
Query: 328 LRLLGKGTFGQVYQVRKK-DTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSP 386
L LG G FG+V V D + +A+K L KK IV + H ERNI++ T S+
Sbjct: 472 LATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMET---STD 528
Query: 387 FIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDND 446
+IV L +F+ +Y++ + GGEL+ L+ G F + A+FY+A ++ LEYLH +
Sbjct: 529 WIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKN 588
Query: 447 IVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPELLMDETGYTKM 505
IVYRDLKPEN LL G + L DFG +K R T TFCGT EY++PE+++++ G+ +
Sbjct: 589 IVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNK-GHDQA 647
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFG--KVKFPRDVLSPEGRSFVKGLLNR 563
D+W+LG+ I E+ G PF ASD K Y I G ++ P + + VK L
Sbjct: 648 ADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRD 707
Query: 564 NPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
NP RLG+ G ++R H +F DWE +R + + PP P + + D +NFD
Sbjct: 708 NPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFD 760
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 190 bits (483), Expect = 6e-48
Identities = 121/359 (33%), Positives = 190/359 (52%), Gaps = 62/359 (17%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EYT + + DF++L ++G+G FG+V R+K T IYAMK L K ++ + ++ H
Sbjct: 91 EYTRLMRNRLCVDDFDLLSIIGRGAFGEVRLCREKKTGNIYAMKKLKKSEMLSRGQVEHV 150
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L AS IV L +SFQ P LYL+ +++SGG++ L +E TE A+F
Sbjct: 151 RAERNLLAEVASDC---IVKLYYSFQDPEYLYLIMEYLSGGDVMTLLMREETLTETVARF 207
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFG---------LSKADLKDRT 481
YIA+ VLA+E +H ++ V+RD+KP+N+LLD G++ L DFG +S ++ +
Sbjct: 208 YIAQSVLAIESIHKHNYVHRDIKPDNLLLDKYGHMKLSDFGLCKPLDCRNISAMNVNEPL 267
Query: 482 N------------------------------------------TFCGTTEYLAPELLMDE 499
N + GT +Y+APE+L+ +
Sbjct: 268 NDENINESIDGDENCSIGRRGRRWKSPLEQLQHWQINRRKLAYSTVGTPDYIAPEVLLKK 327
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEGRSF 556
GY D+WSLG +++EM G+ PF++ D +KI + + FP L+PE R
Sbjct: 328 -GYGVECDWWSLGAIMYEMLVGYPPFYSDDPVTTCRKIVSWRTHLVFPEGARLTPEARDL 386
Query: 557 VKGLLNRNPKHRLGAIDDGRE-LRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNF 614
+ LL + +HRLG+ G E ++AH +F D++WE + + + FKP + E DT NF
Sbjct: 387 ICRLL-CDSEHRLGSHGAGAEQIKAHTWFKDVEWEKLYE--MDAAFKPVVNGELDTQNF 442
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 189 bits (481), Expect = 1e-47
Identities = 123/352 (34%), Positives = 199/352 (55%), Gaps = 25/352 (7%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
K Q +D++V++++G+G FG+V VR K + ++YAMK+LSK ++K+++ A ER+
Sbjct: 83 KGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERD 142
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
I+ A +SP++V L ++FQ LY+V ++M GG+L +L E AKFY AE+
Sbjct: 143 IM---AFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKFYTAEV 198
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFG-LSKADLKD--RTNTFCGTTEYLA 492
VLAL+ +H +++RD+KP+N+LLD +G++ L DFG K D +T GT +Y++
Sbjct: 199 VLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYIS 258
Query: 493 PELLMDETG---YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRD 547
PE+L + G Y + D+WS+GV ++EM G +PF+A Y KI K + FP D
Sbjct: 259 PEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPED 318
Query: 548 V-LSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLI 606
+S ++ + L + + RLG + E+R HPFF + W ++ P P L
Sbjct: 319 AEISKHAKNLICAFLT-DREVRLGR-NGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELS 376
Query: 607 SETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAM---QAKFVGFTFVDESAI 655
S+ D+SNFD +K + P+ A Q F+GFT+ E+ +
Sbjct: 377 SDIDSSNFDDIED-------DKGDVETFPIPKAFVGNQLPFIGFTYYRENLL 421
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 189 bits (480), Expect = 1e-47
Identities = 124/358 (34%), Positives = 183/358 (50%), Gaps = 61/358 (17%)
Query: 312 YTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTI 371
Y K+ + F ++ LG G FG+V RK DT +YA K L KK ++ +N++AH
Sbjct: 692 YIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVK 751
Query: 372 GERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFY 431
ER+IL A + ++V L +SFQ +LY V D++ GG++ L + G F E A+FY
Sbjct: 752 AERDIL---AEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFY 808
Query: 432 IAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL------------------S 473
IAEL A+E +H ++RD+KP+NIL+D +G+I L DFGL
Sbjct: 809 IAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHP 868
Query: 474 KADLKDRTN-------------------------------TFCGTTEYLAPELLMDETGY 502
+ D D +N + GT Y+APE+L+ TGY
Sbjct: 869 RQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLL-RTGY 927
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF---PRDVLSPEGRSFVKG 559
T++ D+WS+GV++FEM G PF A + K+ + P+ LSPE +
Sbjct: 928 TQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIK 987
Query: 560 LLNRNPKHRLGAIDDGRELRAHPFFNDIDWEA-VRQKKIPPPFKPHLISETDTSNFDP 616
L R P+ RLG + E++AHPFF ID+ + +RQ+ + P + TDTSNFDP
Sbjct: 988 LC-RGPEDRLGK-NGADEIKAHPFFKTIDFSSDLRQQS--ASYIPKITHPTDTSNFDP 1041
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 189 bits (480), Expect = 1e-47
Identities = 122/349 (34%), Positives = 198/349 (55%), Gaps = 25/349 (7%)
Query: 319 QYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
Q +D++V++++G+G FG+V VR K + ++YAMK+LSK ++K+++ A ER+I+
Sbjct: 86 QMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIM- 144
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
A +SP++V L ++FQ LY+V ++M GG+L +L E AKFY AE+VLA
Sbjct: 145 --AFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKFYTAEVVLA 201
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFG-LSKADLKD--RTNTFCGTTEYLAPEL 495
L+ +H +++RD+KP+N+LLD +G++ L DFG K D +T GT +Y++PE+
Sbjct: 202 LDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEV 261
Query: 496 LMDETG---YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-L 549
L + G Y + D+WS+GV ++EM G +PF+A Y KI K + FP D +
Sbjct: 262 LKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEI 321
Query: 550 SPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET 609
S ++ + L + + RLG + E+R HPFF + W ++ P P L S+
Sbjct: 322 SKHAKNLICAFLT-DREVRLGR-NGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDI 379
Query: 610 DTSNFDPEFTQTSTSFMNKQPIAATPLSPAM---QAKFVGFTFVDESAI 655
D+SNFD +K + P+ A Q F+GFT+ E+ +
Sbjct: 380 DSSNFDDIED-------DKGDVETFPIPKAFVGNQLPFIGFTYYRENLL 421
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 188 bits (478), Expect = 2e-47
Identities = 123/359 (34%), Positives = 198/359 (54%), Gaps = 32/359 (8%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+D+EV++++G+G FG+V VR K T ++YAMK+LSK ++K+++ A ER+I+ A
Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIM---AF 130
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
+SP++V L ++FQ LY+V ++M GG+L +L E A+FY AE+VLAL+ +
Sbjct: 131 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWARFYTAEVVLALDAI 189
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD---RTNTFCGTTEYLAPELLMDE 499
H ++RD+KP+N+LLD +G++ L DFG K+ R +T GT +Y++PE+L +
Sbjct: 190 HSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQ 249
Query: 500 TG---YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRD-VLSPEG 553
G Y + D+WS+GV ++EM G +PF+A Y KI K + FP D +S E
Sbjct: 250 GGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEA 309
Query: 554 RSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSN 613
++ + L + + RLG + E++ H FF + W + P P L S+ DTSN
Sbjct: 310 KNLICAFLT-DREVRLGR-NGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSN 367
Query: 614 FDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNNRKFLQNS 672
FD ++ Q FVGFT+ Y+NR++L ++
Sbjct: 368 FD----DLEEDKGEEETFPIPKAFVGNQLPFVGFTY-------------YSNRRYLSSA 409
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 188 bits (477), Expect = 3e-47
Identities = 117/306 (38%), Positives = 175/306 (56%), Gaps = 21/306 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DFE+L+++G+G F +V V+ K T ++YAMK+++K ++K+ E++ ER++LV +
Sbjct: 70 DFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRR 129
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEG-RFTEDRAKFYIAELVLALEYL 442
+I L F+FQ LYLV ++ GG+L L K G R + A+FY+AE+V+A++ +
Sbjct: 130 ---WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSV 186
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLS---KADLKDRTNTFCGTTEYLAPELLMDE 499
H V+RD+KP+NILLD G+I L DFG +AD R+ GT +YL+PE+L
Sbjct: 187 HRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAV 246
Query: 500 TG------YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK----VKFPRDVL 549
G Y D+W+LGV +EM G +PF+A + Y KI K + + +
Sbjct: 247 GGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGV 306
Query: 550 SPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISET 609
E R F++ LL P+ RLG G + R HPFF +DW+ +R PPF P T
Sbjct: 307 PEEARDFIQRLL-CPPETRLGRGGAG-DFRTHPFFFGLDWDGLRDS--VPPFTPDFEGAT 362
Query: 610 DTSNFD 615
DT NFD
Sbjct: 363 DTCNFD 368
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 187 bits (476), Expect = 4e-47
Identities = 99/248 (39%), Positives = 149/248 (59%), Gaps = 7/248 (2%)
Query: 369 HTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRA 428
H E+ +L++ PFIV + S + LY++ +F+ GGE+F +L+ F+ A
Sbjct: 6 HVHNEKRVLLQL---KHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMA 62
Query: 429 KFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTT 488
+FY +E+V ALEY+H IVYRDLKPEN++L G+I + DFG +K +L+DRT T CGT
Sbjct: 63 RFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK-ELRDRTYTICGTP 121
Query: 489 EYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV 548
+YLAPE L TG+ K VD+W+LG+LI+EM G PF ++Y I K+KFPR
Sbjct: 122 DYLAPESLA-RTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRS- 179
Query: 549 LSPEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLIS 607
+ + VK LL + R+G + +G ++++ H +F ++W+ ++ PP P L
Sbjct: 180 FNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYH 239
Query: 608 ETDTSNFD 615
DT NFD
Sbjct: 240 PGDTGNFD 247
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 186 bits (473), Expect = 8e-47
Identities = 105/301 (34%), Positives = 177/301 (57%), Gaps = 17/301 (5%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
F++LR +GKG+FG+V V+K+DT ++YAMK ++K+ ++++E+ + E I+
Sbjct: 23 FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIM---QGLE 79
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
PF+V L +SFQ D+++V D + GG+L +HLQ+ FTE K YI EL LALEYL
Sbjct: 80 HPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQR 139
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELL---MDE- 499
I++RD+KP+NILLD +G++ + DF ++ +R ++ GT Y+APE+ MD
Sbjct: 140 YHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRG 199
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVK--FPRDVLSPEGRSFV 557
GY+ VD+WSLG+ +E+ GW P+ + + + KV+ + +
Sbjct: 200 PGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEILNMFKVERVHYSSTWCKGMVALL 259
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPE 617
+ LL ++P+ R+ ++ D +++ P+ D++W+AV +K + P F P+ N DP
Sbjct: 260 RKLLTKDPESRVSSLHD---IQSVPYLADMNWDAVFKKALMPGFVPN----KGRLNCDPT 312
Query: 618 F 618
F
Sbjct: 313 F 313
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 186 bits (471), Expect = 1e-46
Identities = 118/337 (35%), Positives = 190/337 (56%), Gaps = 29/337 (8%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
P D+E+++ + KG +G+V+ VR++ +IYAMK +SK++++K+ A + E+ +V
Sbjct: 42 PSDYEIVKNVAKGGYGEVFLVRRE---KIYAMKRVSKELVLKQPHTALFMAEKEAMVDCI 98
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
S ++V + Q LY + DF+ GG+ L KE ED +FY AE+V AL+
Sbjct: 99 G--SEWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEEDWVRFYAAEIVAALDE 156
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFG--LSKADLKDRTNTFCGTTEYLAPELLM-- 497
LH ++RDLKP+N+L+ +G++ L DFG + D K R++ GT +Y++P++L
Sbjct: 157 LHKLGWIHRDLKPDNVLIGIDGHVKLADFGSCIKMKDGKARSSITVGTPDYVSPDVLCSV 216
Query: 498 -DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
+E Y + VDFW+LGV+I+EM G +PF++ + Y++I + FP V SPE S
Sbjct: 217 NEECEYGEDVDFWTLGVIIYEMIYGTTPFYSDTLMETYRRITRVEFGFPFKV-SPELTSL 275
Query: 557 VKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNF-D 615
++GL+ K R I+ E+++H FF +DW R K++ PPF P + ++DTS+F D
Sbjct: 276 IEGLI--AAKDRRMRIE---EIKSHAFFEGVDWS--RLKELKPPFVPEVNGDSDTSHFVD 328
Query: 616 PEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDE 652
+F K FVGFTF E
Sbjct: 329 TQFDAEKRKLNVK----------GNYMPFVGFTFDPE 355
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 184 bits (468), Expect = 3e-46
Identities = 124/357 (34%), Positives = 179/357 (49%), Gaps = 59/357 (16%)
Query: 312 YTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTI 371
Y K+ + F ++ LG G FG+V K DT +YAMK L KK ++ +N++ H
Sbjct: 655 YNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVK 714
Query: 372 GERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFY 431
ER+IL A + ++V L +SFQ LY V D++ GG++ L + F E A+FY
Sbjct: 715 AERDIL---AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFY 771
Query: 432 IAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL------------------- 472
IAEL LA+E +H ++RD+KP+NIL+D +G+I L DFGL
Sbjct: 772 IAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHV 831
Query: 473 --------------SKADLKDRTNT----------------FCGTTEYLAPELLMDETGY 502
S DR T GT Y+APE+L+ GY
Sbjct: 832 RQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLL-RKGY 890
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIA--FGKVKFPRDV-LSPEGRSFVKG 559
T++ D+WS+GV++FEM G PF A + K+ + P V LSPE R +
Sbjct: 891 TQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITK 950
Query: 560 LLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP 616
L + HRLG + +L+AHPFF+ ID+ + +K+ P P+ P + DTSNFDP
Sbjct: 951 LC-CSADHRLGR-NGADDLKAHPFFSAIDFSSDIRKQ-PAPYVPTISHPMDTSNFDP 1004
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 184 bits (468), Expect = 3e-46
Identities = 108/288 (37%), Positives = 170/288 (58%), Gaps = 13/288 (4%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
Q F V+R +G+G FG+V V+++ T + +A+K ++K+ ++K A+ I E +L +
Sbjct: 26 QHFSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRCIEKGVAANVIRELTLL---SK 82
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
S PFIV L ++FQ +Y+V+D + GG+L +HL ++G+F EDRAK Y+ E+ LA+EYL
Sbjct: 83 MSHPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRAKLYLCEICLAVEYL 142
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNT-FCGTTEYLAPEL----LM 497
H+ IV+RD+KPENILLD G+ L D L+ D+ T + GT Y+APE+ L
Sbjct: 143 HEMKIVHRDIKPENILLDEQGHAHLTDLNLATQLEDDQLATSYSGTRPYMAPEIYATYLE 202
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPF-FASDNQKMYQKIAFGKVKFPRDVLSPEGR-S 555
E GY VD+W+LGV +EM G +PF F+S + +AF + P P
Sbjct: 203 IEDGYDSRVDWWALGVCFYEMLRGRTPFEFSSRTKPEEAYVAFRESSIPYPAHWPTDLIQ 262
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKP 603
F+ +L + + RL ++ ++ H + ID+++V +KK P F P
Sbjct: 263 FINSMLKFDKEKRLVGLE---AIKKHSYTERIDFKSVFEKKPSPVFIP 307
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 184 bits (468), Expect = 3e-46
Identities = 124/395 (31%), Positives = 201/395 (50%), Gaps = 71/395 (17%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
EY ++R+ G DFE+L ++GKG FG+V R + T +YAMK L K ++ + ++ H
Sbjct: 88 EYMRLQRRKIGIDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKKTEMLSRGQVEHV 147
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L S+ +IV L +SFQ LYL+ +++ GG++ L +E +ED A+F
Sbjct: 148 RSERNLLAEVDSR---YIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMREDILSEDVARF 204
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF------ 484
YIAE +LA+ +H ++ V+RD+KP+N++LD +G++ L DFGL K L D+ ++
Sbjct: 205 YIAESILAIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLCK-PLDDKYSSLLLEDDE 263
Query: 485 -----------------------------------------CGTTEYLAPELLMDETGYT 503
GT +Y+APE+L+ + GY
Sbjct: 264 MLSQDSENQSGKSDADKAPWQMPKEQLLQWKRNRRALAYSTVGTLDYMAPEVLL-KKGYG 322
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKV--KFPRD-VLSPEGRSFVKGL 560
D+WSLG +++EM G+ PF + D + +KI +V KFP + +S E R + L
Sbjct: 323 MECDWWSLGAILYEMLVGYPPFCSDDPRITCRKIINWRVCLKFPEEPKISDEARDLICRL 382
Query: 561 LNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQ 620
L + RLG E+++HP+F W+ + + ++P + E DT NF+ +F +
Sbjct: 383 L-CDVDSRLGT-RGVEEIKSHPWFKGTPWDKLYD--MEAAYRPIVDGELDTQNFE-KFPE 437
Query: 621 TSTSFMNKQPIAATPLSP------AMQAKFVGFTF 649
S P A + P + F+GFTF
Sbjct: 438 VEGS-----PSEAPQVGPWRKMLTSKDTNFIGFTF 467
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 184 bits (467), Expect = 4e-46
Identities = 109/298 (36%), Positives = 169/298 (56%), Gaps = 11/298 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVRK--KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
D EV+ LG G FG+V V+ +D + I+A+K L K+ IV + H ER+I++
Sbjct: 456 DLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIML--- 512
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
S SPFI L +F+ +Y++ + GGE++ L+ G F ++ A+F I ++ A EY
Sbjct: 513 SSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEY 572
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLMDET 500
LH I+YRDLKPEN++LD G + + DFG +K +T TFCGT EY+APE+++++
Sbjct: 573 LHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNK- 631
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFG--KVKFPRDVLSPEGRSFVK 558
G+ + VD+W+LG+LI E+ G PF A D + Y I G + FP+ + S +K
Sbjct: 632 GHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHI-SRWAVQLIK 690
Query: 559 GLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
L P RLG G ++++ H +F DW+ + + + PPF + TD FD
Sbjct: 691 RLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFD 748
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 184 bits (467), Expect = 4e-46
Identities = 122/370 (32%), Positives = 205/370 (54%), Gaps = 46/370 (12%)
Query: 315 TKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGER 374
T+K + DF + L+G+G FG V+ V ++ T IYAMK + K V+ + ER
Sbjct: 103 TRKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTT----SQVKEER 158
Query: 375 NILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAE 434
+I+ + ++S +++ L+++FQ +LYLV ++M GG+L + + G F ED A+FY+AE
Sbjct: 159 DIM---SIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAE 215
Query: 435 LVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD---RTNTFCGTTEYL 491
L +AL LH+ V+RD+KPENIL+D G+I L DFG + A +D + + GT +Y+
Sbjct: 216 LTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYI 275
Query: 492 APELL-------MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAF----- 539
APELL + ++ + D+WS+G++ +E+ C +PF + + Y KI
Sbjct: 276 APELLQTISTYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEES 335
Query: 540 ---GKVKFPRDV-LSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQK 595
+ FP D+ +S R+ ++ L+ NP RL ++ HPFF++I W ++R +
Sbjct: 336 HLKELISFPADLKVSVNYRNLIESLVT-NPSKRLSY----ERIKNHPFFSEIPWGSIRSQ 390
Query: 596 KIPPPFKPHLISETDTSNFDPEFTQTSTSFMNKQPIAATPLSPAMQAK--------FVGF 647
PP P + S+ DTSNF+ + +Q +A L+ M++ F+G+
Sbjct: 391 --VPPIIPTVRSDDDTSNFEDGIRHKT---RREQGVAKKSLTTNMKSNDFSGKDLPFIGY 445
Query: 648 TFV--DESAI 655
+FV ++SAI
Sbjct: 446 SFVHMEKSAI 455
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 182 bits (463), Expect = 1e-45
Identities = 119/340 (35%), Positives = 192/340 (56%), Gaps = 22/340 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF L+++G+G FG+V+ VR T +YAMK+L+K ++K+ + A ER+I+ A
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIM---AHA 123
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+S +IV L+++FQ P LY+V ++M GG+L +L +E +FY AE+V AL LH
Sbjct: 124 NSEWIVRLQYAFQDPRHLYMVMEYMPGGDLV-NLMTSYEVSEKWTRFYTAEIVEALAALH 182
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGL---SKADLKDRTNTFCGTTEYLAPELLMD-- 498
++RD+KP+N+L+ +G+I L DFG A+ R +T GT +Y++PE+L +
Sbjct: 183 SMGYIHRDVKPDNMLISISGHIKLADFGTCVKMNANGVVRCSTAVGTPDYISPEVLRNQG 242
Query: 499 -ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRD-VLSPEGR 554
+ + K VD+WS+GV I+EM G +PF+A Y I K +KFP + ++S + +
Sbjct: 243 QDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQAK 302
Query: 555 SFVKGLLNRNPKHRLG--AIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
+K L+ P RLG ++DD +R H FF + +W ++ PP P L S+ DT+
Sbjct: 303 DIIKKFLSAAP-DRLGRNSVDD---IRNHKFFVNDEWTFATLREASPPVIPSLKSDDDTT 358
Query: 613 NFDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDE 652
+F+ T+ N Q F+GFT+ +E
Sbjct: 359 HFEEIETRDRD---NAGDFQLPKTFNGNQLPFIGFTYSNE 395
>CE01554 [T] KOG0986 G protein-coupled receptor kinase
Length = 642
Score = 182 bits (463), Expect = 1e-45
Identities = 115/319 (36%), Positives = 180/319 (56%), Gaps = 31/319 (9%)
Query: 308 IHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEI 367
+ W++ +KR F + R+LGKG FG+V + + + ++YA+K L KK + K++
Sbjct: 188 LQWKWL--EKRPVDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAE 245
Query: 368 AHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQK--EGRFTE 425
++ E+ IL R +SPF+V L ++++T L LV M+GG+L +HL G F E
Sbjct: 246 TLSLNEKQILQRI---NSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDE 302
Query: 426 DRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNT 483
R +FY AE+ L L++LH I+YRDLKPENILLD G++ + D GL+ ++KD
Sbjct: 303 KRVQFYAAEITLGLQHLHSERILYRDLKPENILLDDFGHVRISDLGLA-VEIKDNEPIKG 361
Query: 484 FCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFAS----DNQKMYQKIAF 539
GT Y+APE++ +E Y+ VD+W +G LI+EM G +PF +++ +++
Sbjct: 362 RVGTVGYMAPEIVKNER-YSYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVRE 420
Query: 540 GKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGR------ELRAHPFFNDID----- 588
+ K+ + S R+ +GLL++ P RLG GR E+RAHPFFN D
Sbjct: 421 DQEKY-SEKFSEAARTLCRGLLHKEPGFRLGCRRVGRPEDGAEEIRAHPFFNTADTVTGR 479
Query: 589 ----WEAVRQKKIPPPFKP 603
W+ + K+ PPF P
Sbjct: 480 EPVPWKKMEAGKVTPPFCP 498
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 182 bits (461), Expect = 2e-45
Identities = 122/354 (34%), Positives = 187/354 (52%), Gaps = 58/354 (16%)
Query: 312 YTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMR-IYAMKVLSKKVIVKKNEIAHT 370
Y K+ + F L+ +G G FG+V V K DT +YAMK L K ++K+N++AH
Sbjct: 706 YIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHV 765
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER+IL A + ++V L +SFQ +LY V D++ GG+L L K G F E+ A+F
Sbjct: 766 KAERDIL---AEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARF 822
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL------------------ 472
YIAE+ A++ +H ++RD+KP+NIL+D +G+I L DFGL
Sbjct: 823 YIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGN 882
Query: 473 -SKAD----------------------LKDR----TNTFCGTTEYLAPELLMDETGYTKM 505
S+ D ++D ++ GT Y+APE+L + +GYT++
Sbjct: 883 HSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVL-ERSGYTQL 941
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF---PRDVLSPEGRSFVKGLLN 562
D+WS+GV+++EM G PF A+ + QK+ + P+ LS E ++ L
Sbjct: 942 CDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCA 1001
Query: 563 RNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP 616
K RLG D E+++H FF ID+ +R++K P+ P + TDTSNFDP
Sbjct: 1002 SADK-RLGKSVD--EVKSHDFFKGIDFADMRKQK--APYIPEIKHPTDTSNFDP 1050
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 181 bits (459), Expect = 4e-45
Identities = 102/301 (33%), Positives = 170/301 (55%), Gaps = 8/301 (2%)
Query: 319 QYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILV 378
Q + + + LG G FG+V V + A+K++ K +VK+++I H E+N+++
Sbjct: 688 QVAISELKKIATLGCGAFGRVDLVAYNQ--QALALKIIKKIEVVKQDQIEHVYNEKNVMI 745
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
+ + SPFIV L +++ +Y + + GG+++ + K F E AKF +V A
Sbjct: 746 KC--RQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEA 803
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLM 497
+YLH + +YRDLKPEN++L +G L DFG +K ++TNTF GT EY+APE+++
Sbjct: 804 FDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPEIIL 863
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFG-KVKFPRDVLSPEGRSF 556
D G+ + VD+W+LG+L++E+ G +PF + K+YQ+I G V + +
Sbjct: 864 DR-GHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHL 922
Query: 557 VKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
V+ L + P RLG G +++ H +F +DW+ ++ K++P P K L S TD F
Sbjct: 923 VRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTDLQYFG 982
Query: 616 P 616
P
Sbjct: 983 P 983
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 178 bits (452), Expect = 2e-44
Identities = 120/391 (30%), Positives = 191/391 (48%), Gaps = 58/391 (14%)
Query: 311 EYTSTKKRQYGPQ--DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIA 368
E+ +KR+ P+ DF++L +G+G +GQVY +KKD+ I A+K+L+KK++ K NE
Sbjct: 153 EHEVLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETN 212
Query: 369 HTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRA 428
H + ER+IL T S ++V L ++FQ P LYL +F+ GG+ L A
Sbjct: 213 HVLTERDILTTTRSD---WLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHA 269
Query: 429 KFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL---------------- 472
+FYI+E+ A+ LH+ +RDLKPEN L+DA G+I L DFGL
Sbjct: 270 RFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIR 329
Query: 473 ------------SKADLKDR--------------TNTFCGTTEYLAPELLMDETGYTKMV 506
++ ++DR N+ G+ +Y+A E+L + Y V
Sbjct: 330 LEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVL-EGKKYDFTV 388
Query: 507 DFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF---VKGLLNR 563
D+WSLG ++FE G++PF S + Y+ + + K R +F L+ R
Sbjct: 389 DYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITR 448
Query: 564 NPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD-----PEF 618
+ + ++R +F +I++E +R PPF P L ETD FD +
Sbjct: 449 LIADPINRVRSFEQVRKMSYFAEINFETLRTSS--PPFIPQLDDETDAGYFDDFTNEEDM 506
Query: 619 TQTSTSFMNKQPIAATPLSPAMQAKFVGFTF 649
+ + F + ++A A+ +K VGFTF
Sbjct: 507 AKYADVFKRQNKLSAMVDDSAVDSKLVGFTF 537
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 176 bits (446), Expect = 1e-43
Identities = 122/391 (31%), Positives = 189/391 (48%), Gaps = 58/391 (14%)
Query: 311 EYTSTKKRQYGPQ--DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIA 368
E+ +KR+ P+ DFE++ +G+G +GQVY RKKDT + A+K+L+KK++ K NE
Sbjct: 161 EHQVLRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETK 220
Query: 369 HTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRA 428
H + ER+IL T S+ ++V L ++FQ LYL +F+ GG+ L A
Sbjct: 221 HVLTERDILTTTRSE---WLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHA 277
Query: 429 KFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL---------------- 472
+FYI+E+ A+ LHD +RDLKPEN L+DA G+I L DFGL
Sbjct: 278 RFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIR 337
Query: 473 ------------SKADLKDR--------------TNTFCGTTEYLAPELLMDETGYTKMV 506
++ ++DR N+ G+ +Y+A E+L + Y V
Sbjct: 338 LEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVL-EGKKYDFTV 396
Query: 507 DFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF---VKGLLNR 563
D+WSLG ++FE G++PF S + Y + K R S +F L+ R
Sbjct: 397 DYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITR 456
Query: 564 NPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD-----PEF 618
+ + ++ +F DI++ +R + PPF P L SETD FD +
Sbjct: 457 LIADPINRLRSFEHVKRMSYFADINFSTLR--SMIPPFTPQLDSETDAGYFDDFTSEADM 514
Query: 619 TQTSTSFMNKQPIAATPLSPAMQAKFVGFTF 649
+ + F + + A A+ +K VGFTF
Sbjct: 515 AKYADVFKRQDKLTAMVDDSAVSSKLVGFTF 545
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 176 bits (445), Expect = 1e-43
Identities = 117/344 (34%), Positives = 190/344 (55%), Gaps = 29/344 (8%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+DF ++L+G G FG+V VR K + ++YAMK LSK ++K+ + A ER+I+ A
Sbjct: 85 EDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIM---AH 141
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
+S +IV L F+FQ LY+V DFM GG++ L + E A FY E+VLAL+ +
Sbjct: 142 ANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIV-SLMGDYDIPEKWAIFYTMEVVLALDTI 200
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSK---ADLKDRTNTFCGTTEYLAPELLMD- 498
H+ V+RD+KP+N+LLD+ G++ L DFG A+ + ++ GT +Y++PE+L
Sbjct: 201 HNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQ 260
Query: 499 --ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEG 553
+ Y + D+WS+G+ ++EM G +PF+A Y KI K + FP +V +S +
Sbjct: 261 GVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQA 320
Query: 554 RSFVKGLLNRNPKHRLG--AIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDT 611
++ ++ L + RLG I+D ++AHPFF + W ++ PP P L S+ DT
Sbjct: 321 KALIRAFLT-DRTQRLGRYGIED---IKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDT 376
Query: 612 SNFDPEFTQTSTSFMNKQPIAATPLSPAMQAK---FVGFTFVDE 652
NF+ +++P P+ F+GFT+ +
Sbjct: 377 RNFE-------DIERDEKPEEVFPVPKGFDGNHLPFIGFTYTGD 413
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 174 bits (441), Expect = 4e-43
Identities = 121/395 (30%), Positives = 196/395 (48%), Gaps = 67/395 (16%)
Query: 312 YTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTI 371
Y ++ + DF+ + +G+G +G V+ RK+DT I A+K+++K V+ K +EI H +
Sbjct: 195 YLRKRRTRISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVL 254
Query: 372 GERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFY 431
ER+IL + +S ++V L ++FQ +++YL +F+ GG+ L G + AKFY
Sbjct: 255 TERDILT---TANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFY 311
Query: 432 IAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS------------------ 473
E+ LA++ LH ++RDLKPEN L+ A+G+I L DFGLS
Sbjct: 312 ATEMFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIESMKIRLQE 371
Query: 474 -------KADLKDRTNTF--------------CGTTEYLAPELLMDETGYTKMVDFWSLG 512
+ +++R F G+ +Y+APE+L E Y VD+WSLG
Sbjct: 372 VNNVVVPERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGE-NYNHSVDYWSLG 430
Query: 513 VLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF-------PRDV---LSPEGRSFVKGLLN 562
+++E G+ PF S+ + + + + F PRD+ + FV +
Sbjct: 431 CIMYECLSGFPPFSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAWDFVCHCIT 490
Query: 563 RNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEFTQTS 622
+PK R ++ +++ HP+F+ IDW+ VR PPF P L SE D FD +FT +
Sbjct: 491 -DPKDRFCSL---KQVMQHPYFSKIDWKNVR-TAYRPPFVPDLNSEIDAGYFD-DFTNEN 544
Query: 623 -----TSFMNKQPIAATPLSPAMQAK---FVGFTF 649
KQ A ++ + K F+GFTF
Sbjct: 545 DMSKYKEVHEKQAAIANMVNTFNKPKRNAFIGFTF 579
>Hs21166359 [T] KOG0986 G protein-coupled receptor kinase
Length = 553
Score = 174 bits (440), Expect = 6e-43
Identities = 112/329 (34%), Positives = 172/329 (52%), Gaps = 19/329 (5%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
F R+LGKG FG+V V+ K+T ++YA K L KK + KK + E+ IL + S
Sbjct: 191 FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKV---S 247
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAK--FYIAELVLALEYL 442
SPFIV L ++F++ T L LV M+GG+L +H+ G D ++ FY A++ + +L
Sbjct: 248 SPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGMLHL 307
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNT-FCGTTEYLAPELLMDETG 501
H+ IVYRD+KPEN+LLD GN L D GL+ + T GT Y+APE+LM++
Sbjct: 308 HELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPEILMEKVS 367
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPF----FASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
Y+ VD++++G I+EM G +PF + + Q+ +VKF D + E +
Sbjct: 368 YSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDIC 427
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPF--KPHLISETDTSNFD 615
+ L + P+ RLG+ + + R H FF I++ + I PPF P ++ D + D
Sbjct: 428 RLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYAKDIAEID 487
Query: 616 P-------EFTQTSTSFMNKQPIAATPLS 637
EF F A P++
Sbjct: 488 DFSEVRGVEFDDKDKQFFKNFATGAVPIA 516
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 174 bits (440), Expect = 6e-43
Identities = 113/355 (31%), Positives = 181/355 (50%), Gaps = 54/355 (15%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
+YT ++++ F V+ +G G FG+V VRK DT ++YAMK L K ++ K + AH
Sbjct: 488 KYTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHV 547
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER+IL A SP+IV L FSFQ LY + +++ GG++ L ++G F ED A+F
Sbjct: 548 KAERDIL---AEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARF 604
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA--------------- 475
YIAEL A+EY+H+ ++RDLKP+NIL+D +G+I L DFGL
Sbjct: 605 YIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPEND 664
Query: 476 -----------------------DLKDRT-----NTFCGTTEYLAPELLMDETGYTKMVD 507
+++ +T ++ GT Y+APE++ +TG+ + D
Sbjct: 665 HHRVDSFSLPPEVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVIA-KTGHNQSCD 723
Query: 508 FWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPR-DVLSPEGRSFVKGLL--- 561
+WS GV+++EM G PF +I + + F LS E ++ L+
Sbjct: 724 WWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLICDA 783
Query: 562 -NRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFD 615
+R H + +++ HP+F IDW +R+ + + P + + DTSNF+
Sbjct: 784 SSRLGSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHDEDTSNFE 838
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 173 bits (439), Expect = 7e-43
Identities = 112/307 (36%), Positives = 172/307 (55%), Gaps = 15/307 (4%)
Query: 305 DILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKK 364
D + W++ +++ F R+LGKG FG+V + + T ++YA K L KK I K+
Sbjct: 168 DRFLQWKWL--ERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKR 225
Query: 365 NEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGR-- 422
+ + E+ IL + +S F+V L ++++T L LV M+GG+L +H+ G
Sbjct: 226 KGESMALNEKQILEKV---NSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPG 282
Query: 423 FTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRT 481
F E+RA FY AE++ LE LH + VYRDLKPENILLD G+I + D GL+ K D
Sbjct: 283 FEEERALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLI 342
Query: 482 NTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK 541
GT Y+APE+L ++ Y D+W LG LI+EM G SP F +K+ ++ +
Sbjct: 343 RGRVGTVGYMAPEVLNNQR-YGLSPDYWGLGCLIYEMIEGQSP-FRGRKEKVKREEVDRR 400
Query: 542 VKFPRDV----LSPEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKK 596
V +V S E +S K LL ++ K RLG ++G E++ HPFF +++++ +
Sbjct: 401 VLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGM 460
Query: 597 IPPPFKP 603
+ PPF P
Sbjct: 461 LDPPFVP 467
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 173 bits (439), Expect = 7e-43
Identities = 109/286 (38%), Positives = 162/286 (56%), Gaps = 11/286 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
F R+LGKG FG+V + + T ++YA K L KK I K+ A + E+ IL + S+
Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR- 244
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGR--FTEDRAKFYIAELVLALEYL 442
F+V L ++++T L LV M+GG+L +H+ G+ F E RA FY AE+ LE L
Sbjct: 245 --FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDL 302
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT-NTFCGTTEYLAPELLMDETG 501
H IVYRDLKPENILLD +G+I + D GL+ + +T GT Y+APE++ +E
Sbjct: 303 HRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNER- 361
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV---LSPEGRSFVK 558
YT D+W+LG L++EM G SPF + +++ + P + SP+ RS
Sbjct: 362 YTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCS 421
Query: 559 GLLNRNPKHRLGAI-DDGRELRAHPFFNDIDWEAVRQKKIPPPFKP 603
LL ++P RLG RE++ HP F ++++ + + PPFKP
Sbjct: 422 QLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKP 467
>Hs4885347 [T] KOG0986 G protein-coupled receptor kinase
Length = 500
Score = 170 bits (430), Expect = 8e-42
Identities = 112/291 (38%), Positives = 159/291 (54%), Gaps = 21/291 (7%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
F R+LGKG FG+V + + T ++YA K L KK I K+ A + E+ IL + S+
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSR- 213
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGR--FTEDRAKFYIAELVLALEYL 442
F+V L ++++T L LV M+GG+L +H+ G F E RA FY AEL LE L
Sbjct: 214 --FVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDL 271
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGL-SKADLKDRTNTFCGTTEYLAPELLMDETG 501
IVYRDLKPENILLD G+I + D GL ++ R GT Y+APE++ +E
Sbjct: 272 QRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEK- 330
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKV--KFPRDV------LSPEG 553
YT D+W LG LI+EM G SPF +K +K+ + +V + D S +
Sbjct: 331 YTFSPDWWGLGCLIYEMIQGHSPF-----KKYKEKVKWEEVDQRIKNDTEEYSEKFSEDA 385
Query: 554 RSFVKGLLNRNPKHRLGAIDDGRE-LRAHPFFNDIDWEAVRQKKIPPPFKP 603
+S + LL +NP RLG +G ++ HP F DI++ + + PPF P
Sbjct: 386 KSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 168 bits (426), Expect = 2e-41
Identities = 96/241 (39%), Positives = 143/241 (58%), Gaps = 8/241 (3%)
Query: 330 LLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIV 389
+LG G+FG V VR+K YA K++SK+ +V+ ++AH E+++L + PF++
Sbjct: 50 VLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVL---NAARFPFLI 106
Query: 390 GLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVY 449
L S + LYL+ ++GGELF + ++ +F E A+FY A++ LALEY+H ++Y
Sbjct: 107 YLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMY 166
Query: 450 RDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYTKMVDFW 509
RDLKPENILLD G I + DFG +K + RT+T CGT EYLAPE++ Y K VD+W
Sbjct: 167 RDLKPENILLDQRGYIKITDFGFTKR-VDGRTSTLCGTPEYLAPEIVQLRP-YNKSVDWW 224
Query: 510 SLGVLIFEMCCGWSPFFASDNQ--KMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKH 567
+ G+L++E G SPF + MY KI K P + + RS V+ L+ +
Sbjct: 225 AFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMP-SYFTSQLRSLVESLMQVDTSK 283
Query: 568 R 568
R
Sbjct: 284 R 284
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 167 bits (424), Expect = 4e-41
Identities = 110/386 (28%), Positives = 187/386 (47%), Gaps = 70/386 (18%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
F++L LG+G +G V+ +K++T + AMK++ K + + NE+ H + ER+IL T +
Sbjct: 162 FDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNT---N 218
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
S ++V L ++FQ +YL +++ GG+ L +G E++ +FY+AE+V A+ +H
Sbjct: 219 SEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHK 278
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADL--------------------------- 477
++RDLKPEN L+D G+I L DFGLS A +
Sbjct: 279 LGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSAVNPQRPYLTQKQ 338
Query: 478 ------------KDRTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPF 525
+++ N+ G+ EY+APE++ + Y + VD+WSLG + +E G+ PF
Sbjct: 339 RRNIYKALLEKNENKVNSVVGSPEYMAPEVVYGKK-YDRTVDYWSLGCICYECLVGYPPF 397
Query: 526 FASDNQKMYQKIAFGKVKFPRD-------------VLSPEGRSFVKGLLNRNPKHRLGAI 572
S Q+ + + + + R +S E SF+ L I
Sbjct: 398 SGSTLQETWTNLYYWREMLQRPSKNENGIYDKKARSVSDEAWSFITKCLTEPTSRFQSTI 457
Query: 573 DDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP-EFTQTSTSFMN---- 627
E++ HPFF + W +R++ + PPF P L ++ DTS FD Q ++ +
Sbjct: 458 ----EIQKHPFFKRLHWNGLRKRAV-PPFVPRLENQLDTSYFDDFNDEQVLDAYKDVYEK 512
Query: 628 ----KQPIAATPLSPAMQAKFVGFTF 649
+Q + + Q +F+GFTF
Sbjct: 513 QRKAEQKAKSNGVMNGNQRQFLGFTF 538
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 165 bits (418), Expect = 2e-40
Identities = 121/405 (29%), Positives = 194/405 (47%), Gaps = 72/405 (17%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
E+ K+ + DFE+L ++G+G FG+V R++ + IYAMK L K +V + ++ H
Sbjct: 80 EFMRLKRNKISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMVMRGQVEHV 139
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ERN+L A S +IV L +SFQ P LYL+ +++ GG++ L +E ED A+F
Sbjct: 140 RAERNLL---AEVESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLREDVARF 196
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK---------------- 474
YIA+ VLA+E +H + ++RD+KP+N+LLD +G++ L DFGL K
Sbjct: 197 YIAQSVLAIESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQENRAT 256
Query: 475 -----ADLKDRTNTFCGTTEYLAPELLMDETGYTKM------------VDFWSLGVLI-- 515
++ D F T + ++ + +M D+ + VL+
Sbjct: 257 DDETMSEPMDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDYIAPEVLLKK 316
Query: 516 -FEMCCGW--------------SPFFASDNQKMYQKIAFGK--VKFPRDV-LSPEGRSFV 557
+ M C W PF+A D +KI + +KFP D S E + +
Sbjct: 317 GYGMECDWWSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPEDAKFSSEAKDLI 376
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNF--- 614
LL N HRLG ++++ HP+F D+ WE + + + +KP + E DT NF
Sbjct: 377 CRLL-CNVDHRLGTGGGAQQIKDHPWFKDVVWEKLYE--MEAAYKPEVNDELDTQNFMKF 433
Query: 615 ----DPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAI 655
P +T + K +A LS FVG+T+ + A+
Sbjct: 434 DEVNSPAPERTRSGLSRKMLLAPKDLS------FVGYTYKNFDAV 472
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 164 bits (416), Expect = 3e-40
Identities = 100/269 (37%), Positives = 149/269 (55%), Gaps = 9/269 (3%)
Query: 315 TKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGER 374
+KKRQ+ +DFE+ R LGKG FG VY R+K + I A+KVL K + K + H + R
Sbjct: 123 SKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG-VEHQL-RR 180
Query: 375 NILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAE 434
+ +++ + P I+ L F T +YL+ ++ G ++ LQK +F E R YI E
Sbjct: 181 EVEIQSHLRH-PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITE 239
Query: 435 LVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPE 494
L AL Y H +++RD+KPEN+LL + G + + DFG S R T CGT +YL PE
Sbjct: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE 299
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
++ + + + VD WSLGVL +E G PF A+ Q+ Y++I+ + FP D ++ R
Sbjct: 300 MI-EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFP-DFVTEGAR 357
Query: 555 SFVKGLLNRNPKHRLGAIDDGRELRAHPF 583
+ LL NP R RE+ HP+
Sbjct: 358 DLISRLLKHNPSQRPML----REVLEHPW 382
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 164 bits (415), Expect = 5e-40
Identities = 97/264 (36%), Positives = 153/264 (57%), Gaps = 11/264 (4%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ +LLG G F +V+ R + T + A+K+L+KK ++ +A+ I ++R S
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSH- 79
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L T + ++ +F+ GGELF + K GR +ED ++ Y +L+ A+ Y H
Sbjct: 80 -PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHA 138
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR----TNTFCGTTEYLAPELLMDET 500
+ +RDLKPEN+L+D NGN+ + DFGLS + R +T CGT Y+APE+L +
Sbjct: 139 RGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKG 198
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
VD WS G+++F + G+ PF + MY+KI G+ +FPR +SP+ + FV L
Sbjct: 199 YEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPR-WMSPDLKRFVSRL 257
Query: 561 LNRNPKHRLGAIDDGRELRAHPFF 584
L+ NP+ R+ ID E+ P+F
Sbjct: 258 LDINPETRI-TID---EILKDPWF 277
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 160 bits (405), Expect = 7e-39
Identities = 96/255 (37%), Positives = 146/255 (56%), Gaps = 7/255 (2%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
K+ + +F++ RLLG+G FG VY R+K++ + A+KVL K+ I + N + H + R I
Sbjct: 146 KKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESN-VEHQV-RREI 203
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEG--RFTEDRAKFYIAE 434
+++ + P I+ L F +YL+ ++ G LF LQ + RF E ++ YI
Sbjct: 204 EIQSHLRH-PHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQA 262
Query: 435 LVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPE 494
L AL YLH+ DI++RD+KPEN+LL G + + DFG S + T CGT +YL PE
Sbjct: 263 LCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPE 322
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
++ + +TK VD WSLGVL FE+ G +PF++ + + Y+KI K P + S
Sbjct: 323 MVQGKP-HTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHI-SKAAS 380
Query: 555 SFVKGLLNRNPKHRL 569
+ LL NP+HRL
Sbjct: 381 HLISKLLVLNPQHRL 395
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 160 bits (404), Expect = 8e-39
Identities = 107/323 (33%), Positives = 176/323 (54%), Gaps = 22/323 (6%)
Query: 308 IHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEI 367
+ W++ + Y + F + R+LGKG FG+V + + T ++YA K L KK I K+
Sbjct: 294 LQWKWLEAQPITY--KTFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGE 351
Query: 368 AHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGR---FT 424
+ + E+ IL + +SPF+V L ++++T L LV M+GG+L +H+ G F
Sbjct: 352 SMVLIEKQILQKI---NSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFE 408
Query: 425 EDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRTNT 483
+RA+FY AE+ L++LH IVYRD KPENILLD +G++ + D GL+ + +
Sbjct: 409 LERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGEMVRG 468
Query: 484 FCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVK 543
GT Y+APE++ D Y D++S G L++EM G +P F +K+ ++ +VK
Sbjct: 469 RVGTVGYMAPEVI-DNEKYAFSPDWFSFGCLLYEMIEGQAP-FRMRKEKVKREEVDRRVK 526
Query: 544 FPRDVLS----PEGRSFVKGLLNRNPKHRLGAID---DGRELRAHPFFN--DIDWEAVRQ 594
+ S E +S + LL ++ K RLG + G+++ AHPFF+ ++W +
Sbjct: 527 EDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEA 586
Query: 595 KKIPPPF--KPHLISETDTSNFD 615
+ PPF PH + D + +
Sbjct: 587 GMLEPPFVPDPHAVYAKDVLDIE 609
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 157 bits (398), Expect = 4e-38
Identities = 127/404 (31%), Positives = 191/404 (46%), Gaps = 74/404 (18%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIV-------------KKNE---- 366
DF+ +R+LG+G +G+V V+ +T ++YAMK L K I+ KN+
Sbjct: 127 DFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNN 186
Query: 367 ---------IAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHL 417
+ T ER+IL + P IV L +SF + LYL+ ++ GGELF+HL
Sbjct: 187 DNDDGLSKRLERTFAERSIL---SEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHL 243
Query: 418 QKEGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--- 474
++ G E FY AE+ AL +LH +VYRDLKPEN LL+ G++ L DFGLSK
Sbjct: 244 KEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSA 303
Query: 475 ----ADLKDRTN-----TFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPF 525
D +D N + GT EY APE+L+ + Y++ D++SLG L+++M G P+
Sbjct: 304 NDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKA-YSQNCDWYSLGCLLYDMLVGKPPY 362
Query: 526 FASDNQKMYQKIAFGKV--KFP-------RDVLSP-----------EGRSFVKGLLNRNP 565
S+++ + KI K K P +D+L+ + + K N P
Sbjct: 363 TGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNKP 422
Query: 566 ----KHRLGAIDDGRELRAHPFFNDIDWEAVR----QKKIPPPFKPHLISETDTSNFDPE 617
K + GA H F IDW+ + QK P P + NFD E
Sbjct: 423 TKSKKKKSGAARTSL-FTEHFIFRKIDWKLLESGQLQKTTLGPIVPVITDLELAENFDTE 481
Query: 618 FTQTS--TSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHY 659
FT S ++ + +PI +S + F GF++ + E Y
Sbjct: 482 FTSMSYEETYTDSKPININSVSKSPD-MFKGFSYKASGSYLEKY 524
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 157 bits (398), Expect = 4e-38
Identities = 102/265 (38%), Positives = 144/265 (53%), Gaps = 14/265 (5%)
Query: 313 TSTKKRQYGPQD-----FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEI 367
TS K + PQ +E+ +LLG GTF +VY R T A+KV+ K+ ++K I
Sbjct: 9 TSLPKERSSPQALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLI 68
Query: 368 AHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDR 427
AH E +IL R P IV L T +Y V +++ GGELF + K GR E+
Sbjct: 69 AHIKREISILRRVRH---PNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAK-GRLKEEV 124
Query: 428 AKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT----NT 483
A+ Y +L+ A+ + H + +RDLKPEN+LLD NGN+ + DFGLS + R +T
Sbjct: 125 ARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHT 184
Query: 484 FCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVK 543
FCGT Y+APE+L + VD WS GV++F + G+ PF + MY+KI G+ +
Sbjct: 185 FCGTPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFR 244
Query: 544 FPRDVLSPEGRSFVKGLLNRNPKHR 568
PR S E + LL NP+ R
Sbjct: 245 CPR-WFSTELTRLLSKLLETNPEKR 268
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 157 bits (398), Expect = 4e-38
Identities = 99/275 (36%), Positives = 158/275 (57%), Gaps = 19/275 (6%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G +D+ V+ L+G+G+FG+VY+ R+K T + AMK + K+ K ++ H++ + ++R
Sbjct: 2 GVEDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQG--KTDKDIHSLRQEIEILRK 59
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
+ I+ + SF+ + +VT+F G ELF L+ + E++ + +LV AL+
Sbjct: 60 LKHEN--IIEMLDSFENAREFCVVTEFAQG-ELFEILEDDKCLPEEQVQAIAKQLVKALD 116
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFC-----GTTEYLAPEL 495
YLH N I++RD+KP+NIL+ A + LCDFG ++A TNT GT Y+APEL
Sbjct: 117 YLHSNRIIHRDMKPQNILIGAGSVVKLCDFGFARA---MSTNTVVLRSIKGTPLYMAPEL 173
Query: 496 LMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRS 555
+ ++ Y + VD WSLGV+++E+ G PF+ + + + I VK+P D +S S
Sbjct: 174 VKEQP-YDRTVDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKDPVKYP-DEMSTYFES 231
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWE 590
F+KGLLN+ P RL LR HPF + E
Sbjct: 232 FLKGLLNKEPHSRL----TWPALREHPFVKETQEE 262
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 157 bits (397), Expect = 6e-38
Identities = 90/265 (33%), Positives = 152/265 (56%), Gaps = 17/265 (6%)
Query: 310 WEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAH 369
W+ +T R+ F + +LG G F +V+ V+++ T +++A+K + K + + + +
Sbjct: 12 WKKQTTNIRK----TFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN 67
Query: 370 TIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAK 429
I +L + ++ IV L+ +++ T YLV +SGGELF + + G +TE A
Sbjct: 68 EIA---VLKKIKHEN---IVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDAS 121
Query: 430 FYIAELVLALEYLHDNDIVYRDLKPENILL---DANGNIALCDFGLSKADLKDRTNTFCG 486
I +++ A++YLH+N IV+RDLKPEN+L + N I + DFGLSK + +T CG
Sbjct: 122 LVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACG 181
Query: 487 TTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR 546
T Y+APE+L + Y+K VD WS+GV+ + + CG+ PF+ K+++KI G +F
Sbjct: 182 TPGYVAPEVLAQKP-YSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFES 240
Query: 547 ---DVLSPEGRSFVKGLLNRNPKHR 568
D +S + F+ LL ++P R
Sbjct: 241 PFWDDISESAKDFICHLLEKDPNER 265
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 156 bits (395), Expect = 9e-38
Identities = 96/260 (36%), Positives = 141/260 (53%), Gaps = 10/260 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
FE+ + LGKG FG+VY ++K T I A+K L K +V+ E I K+
Sbjct: 118 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 177
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
I+ L F +YL+ +F GEL+ HL++ RF+E+ A YI ++ AL YLH
Sbjct: 178 ---ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHK 234
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYTK 504
+++RD+KPENILL +G I L DFG S +R T CGT +YL PE +++ +T+
Sbjct: 235 KHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPE-MVEGKEHTE 293
Query: 505 MVDFWSLGVLIFEMCCGWSPF-FASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
VD WSLGVL +E G PF S + Y++IA +K P + P+ R + LL
Sbjct: 294 KVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIP-SFVPPDARDLISRLLQH 352
Query: 564 NPKHRLGAIDDGRELRAHPF 583
NP+ R+ ++ HP+
Sbjct: 353 NPEKRMSL----EQVMRHPW 368
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 155 bits (391), Expect = 3e-37
Identities = 99/303 (32%), Positives = 162/303 (52%), Gaps = 26/303 (8%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G +DF+ ++G G + V DT + YA KVL+K+ ++++ ++ + E+ L +
Sbjct: 175 GIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKL 234
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
+SP +V L +FQ + LY + ++ G+ ++K G E A++Y A+++ A++
Sbjct: 235 --NNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAID 292
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA-------------DLKDRTNTFCGT 487
YLH N I++RD+KPENILLD I L DFG +K DL R+ +F GT
Sbjct: 293 YLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGT 352
Query: 488 TEYLAPELLMDE-TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR 546
EY++PELL D T Y D W+ G ++F+M G PF A++ +QK+ KV++
Sbjct: 353 AEYVSPELLNDSFTDY--RCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVM--KVQYAF 408
Query: 547 DVLSP-EGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDW-EAVRQKKIPPPFKPH 604
P R VK +L +N RL +++ H FF D+++ + K PP KP+
Sbjct: 409 TPGFPLIIRDLVKKILVKNLDRRLTI----SQIKEHHFFKDLNFKDGSVWSKTPPEIKPY 464
Query: 605 LIS 607
I+
Sbjct: 465 KIN 467
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 154 bits (389), Expect = 5e-37
Identities = 99/296 (33%), Positives = 153/296 (51%), Gaps = 24/296 (8%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF+ +LG+G++ V + T R YA+KVL K+ I+K+ + + E+ L +
Sbjct: 98 DFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKH 157
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
P + L ++FQ +LY V GEL ++ K GRF E A++Y A +V +++Y+H
Sbjct: 158 --PGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMH 215
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSK---------------ADL-KDRTNTFCGT 487
+++RDLKPENILLD N + DFG +K AD + + +F GT
Sbjct: 216 GRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGT 275
Query: 488 TEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRD 547
Y++PE+L D+ T D W+ G ++F+M G PF A + +Q I + P D
Sbjct: 276 ARYVSPEVLSDKIAGTAS-DIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPD 334
Query: 548 VLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKP 603
+ S +K LL +PK RL +D E+ HPFFN I ++ + PP KP
Sbjct: 335 I-SDVASDLIKKLLVLDPKDRL-TVD---EIHQHPFFNGIKFDNTLWELPPPRLKP 385
>CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 392
Score = 154 bits (389), Expect = 5e-37
Identities = 101/281 (35%), Positives = 155/281 (54%), Gaps = 16/281 (5%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKK---DTMRIYAMKVLSKKVIVK-KNEIAHTIGERNILV 378
+DFE+L+ +G G +G+V VRK DT IYAMKV+ K+ + K K+ + H E IL
Sbjct: 27 EDFEILKHIGSGAYGEVAAVRKLNGCDTETIYAMKVMEKRRMSKHKDMVEH---EWKILT 83
Query: 379 RTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLA 438
+PF + + +SFQT L V F GG++ ++ E E+ A FY+ ELV
Sbjct: 84 TI---HNPFFMKMSYSFQTKRHLVFVMPFAGGGDMLTMMENEC-LIEESAHFYLCELVEG 139
Query: 439 LEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELL 496
+ YLH+ IV+RD+K EN+L+ +G++ + D+GLS D +D GT +APE+
Sbjct: 140 IGYLHEKHIVHRDVKLENLLIGNDGHLMITDYGLSATGCDAEDAIQGVIGTRHTMAPEVH 199
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
+ E Y D+W++G+ +M + F +D+++ A + + P+ VLSP R F
Sbjct: 200 L-EKKYGTSCDWWAVGITYCDMRSDKAVFDGADSKEYSDSTAKKRPRLPK-VLSPRERGF 257
Query: 557 VKGLLNRNPKHRLGAIDDG-RELRAHPFFNDIDWEAVRQKK 596
V L+ R+P RLG DG ++AH F + WE V KK
Sbjct: 258 VNKLIVRDPTQRLGNGPDGTATVKAHDMFKGVVWEDVLAKK 298
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 153 bits (387), Expect = 8e-37
Identities = 100/284 (35%), Positives = 147/284 (51%), Gaps = 17/284 (5%)
Query: 318 RQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNIL 377
R + DFE+ R LGKG FG VY R+K + I A+KVL K I K+ + H + R I
Sbjct: 70 RHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEG-VEHQL-RREIE 127
Query: 378 VRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVL 437
++ A P I+ L F +YL+ ++ GEL+ LQK F E R + EL
Sbjct: 128 IQ-AHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELAD 186
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLM 497
AL Y H +++RD+KPEN+LL G + + DFG S R T CGT +YL PE++
Sbjct: 187 ALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMI- 245
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG-RSF 556
+ + + VD W +GVL +E+ G PF ++ + + Y++I +KFP V P G +
Sbjct: 246 EGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV--PTGAQDL 303
Query: 557 VKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPP 600
+ LL NP RL ++ AHP W +++ PP
Sbjct: 304 ISKLLRHNPSERLPL----AQVSAHP------WVRANSRRVLPP 337
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 153 bits (387), Expect = 8e-37
Identities = 99/284 (34%), Positives = 146/284 (50%), Gaps = 17/284 (5%)
Query: 318 RQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNIL 377
R+ DFE+ R LGKG FG VY R K++ I A+KVL K I K+ + H + R I
Sbjct: 2 RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEG-LEHQL-RREIE 59
Query: 378 VRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVL 437
++ A P I+ L F +YL+ ++ GEL+ LQK + E R I E+
Sbjct: 60 IQ-AHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVAD 118
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLM 497
AL Y HD +++RD+KPEN+LL G + + DFG S T CGT +YL PE++
Sbjct: 119 ALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKTMCGTLDYLPPEMIE 178
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG-RSF 556
T Y + VD W +GVL +E+ G+ PF ++ + + Y++I V+FP + P G R
Sbjct: 179 GRT-YDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSM--PLGARDL 235
Query: 557 VKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPP 600
+ LL P RL ++ HP W +++ PP
Sbjct: 236 ISRLLRYQPLERLPL----AQILKHP------WVQAHSRRVLPP 269
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 152 bits (385), Expect = 1e-36
Identities = 95/301 (31%), Positives = 156/301 (51%), Gaps = 35/301 (11%)
Query: 318 RQYGPQDFEVLRLLGKGTFGQVYQ-VRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
R+ P DF LG G++ V++ + KK +IYA+KV SKK I+K+ ++ + E+N
Sbjct: 4 RKRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNT 63
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
+ A K I+ L ++F +LY V DF GGEL L K G F + + + A+L+
Sbjct: 64 MNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLI 123
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA-----------------DLKD 479
ALE++H + I++RDLKPEN+LLD +G + + DFG + KD
Sbjct: 124 DALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKD 183
Query: 480 RTN--TFCGTTEYLAPELLM-DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQK 536
N +F GT EY++PELL+ ++ GY D W+LG +I++ G PF + K ++K
Sbjct: 184 NQNCASFVGTAEYVSPELLLYNQCGYGS--DIWALGCMIYQFVQGQPPFRGENELKTFEK 241
Query: 537 IAF--------GKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDID 588
I ++ ++P + V+ +L R+ +++ HP+F+ +D
Sbjct: 242 IVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISL----EQIKRHPYFSKVD 297
Query: 589 W 589
W
Sbjct: 298 W 298
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 152 bits (383), Expect = 2e-36
Identities = 90/226 (39%), Positives = 129/226 (56%), Gaps = 8/226 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ RLLG GTF +VY R + A+KV+ K+ ++K IAH E +IL R
Sbjct: 28 YEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHIKREISILRRVRH-- 85
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L T + +Y V +++ GGELF + K GR E+ A+ Y +L+ A+ + H
Sbjct: 86 -PNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAK-GRLKEEMARKYFQQLISAVSFCHF 143
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT----NTFCGTTEYLAPELLMDET 500
+ +RDLKPEN+LLD NGN+ + DFGLS + R +TFCGT Y+APE+L +
Sbjct: 144 RGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKG 203
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR 546
VD WS GV++F + G+ PF + MY+KI G + PR
Sbjct: 204 YDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGDFRCPR 249
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 152 bits (383), Expect = 2e-36
Identities = 93/268 (34%), Positives = 152/268 (56%), Gaps = 10/268 (3%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
++Q+ DFE+ R LGKG FG+VY R+ + I A+KV+ K+ I +K +I H + R +
Sbjct: 14 EKQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQI-EKYKIHHQL-RREM 71
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
++T+ + P I+ L F ++L+ ++ GGEL+ L++ G TE +A YIA L
Sbjct: 72 EIQTSLRH-PNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLS 130
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELL 496
AL Y H +++RD+KPEN+LLD G + + DFG S ++ T CGT +YLAPE +
Sbjct: 131 QALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWS-VQSSNKRKTMCGTLDYLAPE-M 188
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFP-RDVLSPEGRS 555
++ + VD W+LG+L +E G PF A + +++I + FP +S E ++
Sbjct: 189 VENRDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKN 248
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPF 583
+ LL ++P RL ++ HP+
Sbjct: 249 LISQLLVKDPSKRLSI----EKIMQHPW 272
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 151 bits (382), Expect = 3e-36
Identities = 100/294 (34%), Positives = 157/294 (53%), Gaps = 12/294 (4%)
Query: 303 TGDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIV 362
T +IH K + DFE+ + LGKG FG+VY VR + T I A+KV+ K+ I+
Sbjct: 82 TSSKMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEII 141
Query: 363 KKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGR 422
K N R + ++T S + P + F +YL+ +++ GE++ L+ G
Sbjct: 142 KYN--LQKQFRREVEIQT-SLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGP 198
Query: 423 FTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKAD-LKDRT 481
F + A YI ++ AL+Y+H +I++RD+KPENIL+ N I L DFG S + ++R
Sbjct: 199 FNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRR 258
Query: 482 NTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK 541
T CGT +YL+PE +++ Y +D W+LGVL FE+ G PF Y++IA
Sbjct: 259 KTVCGTIDYLSPE-MVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALD 317
Query: 542 VKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFF--NDIDWEAVR 593
+K P ++ S + + + LL +PK R+ D ++ HP+ N WE R
Sbjct: 318 IKMPSNI-SQDAQDLILKLLKYDPKDRMRLGD----VKMHPWILRNKPFWENKR 366
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 151 bits (382), Expect = 3e-36
Identities = 96/266 (36%), Positives = 156/266 (58%), Gaps = 19/266 (7%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+ + VL ++G+G+FG+VY+ R+K + ++ A+K + K +K E+ + E I+
Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEK-ELRNLQREIEIM---RG 57
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
P IV + SF+T ++ +VTD+ G ELF L+ +G+ ED+ + A+LV AL YL
Sbjct: 58 LRHPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYL 116
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFC-----GTTEYLAPELLM 497
H + I++RD+KP+NILL G I LCDFG ++A TNT GT Y++PE L+
Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIKLCDFGFARA---MSTNTMVLTSIKGTPLYMSPE-LV 172
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
+E Y D WS+G +++E+ G PF+A+ ++ I V++P +SP ++F+
Sbjct: 173 EERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWP-STISPCFKNFL 231
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPF 583
+GLL ++P+ RL D L HPF
Sbjct: 232 QGLLTKDPRQRLSWPD----LLYHPF 253
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 151 bits (381), Expect = 4e-36
Identities = 91/251 (36%), Positives = 142/251 (56%), Gaps = 13/251 (5%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
FE LG G F +V +K T +++A+K + KK + K E I V K
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSI----ENEIAVLRKIKH 78
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
IV L+ +++P LYLV +SGGELF + ++G +TE A I +++ A+ YLH
Sbjct: 79 EN-IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHR 137
Query: 445 NDIVYRDLKPENILL---DANGNIALCDFGLSKADLK-DRTNTFCGTTEYLAPELLMDET 500
IV+RDLKPEN+L D I + DFGLSK + K D +T CGT Y+APE+L +
Sbjct: 138 MGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR---DVLSPEGRSFV 557
Y+K VD WS+GV+ + + CG+ PF+ ++ K++++I + +F D +S + F+
Sbjct: 198 -YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
Query: 558 KGLLNRNPKHR 568
+ L+ ++P R
Sbjct: 257 RNLMEKDPNKR 267
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 150 bits (380), Expect = 5e-36
Identities = 91/266 (34%), Positives = 152/266 (56%), Gaps = 11/266 (4%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF+V R LGKG FG V+ R+K T RI A+KVL K +++ ++H + +R I ++ +
Sbjct: 43 DFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLG-VSHQL-KREIEIQYHLR 100
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEG--RFTEDRAKFYIAELVLALEY 441
P I+ L F ++++ D+ S GELF LQ + + E A ++ +L AL Y
Sbjct: 101 H-PNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHY 159
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETG 501
H +++RD+KPEN+LLD+ N+ L DFG S + +T CGT +YLAPE++ ++
Sbjct: 160 CHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHSKRHTLCGTMDYLAPEMVSNQP- 218
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
+ VD W++G+L+FEM G++PF K+ +I K+ P V++ S + ++
Sbjct: 219 HDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIP-SVVTDGAASLINAII 277
Query: 562 NRNPKHRLGAIDDGRELRAHPFFNDI 587
+ P+ RL +D + AHP+ ++
Sbjct: 278 KKEPQERLPLVD----IMAHPWIKEM 299
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 150 bits (380), Expect = 5e-36
Identities = 100/303 (33%), Positives = 158/303 (52%), Gaps = 27/303 (8%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
KR+ G +EV R +G+GTF +V R +T A+K+L K+ ++K +++A I R I
Sbjct: 8 KRRVGK--YEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLK-HKMAEQI-RREI 63
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
K P +V L + T ++++ ++++GGELF + +GR ED A+ Y +L+
Sbjct: 64 ATMKLIKH-PNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLI 122
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR----TNTFCGTTEYLA 492
A++Y H + +RDLKPEN+LLD+ GN+ + DFGLS + R +T CGT Y+A
Sbjct: 123 HAVDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVA 182
Query: 493 PELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPE 552
PE+L D D WS GV+++ + G+ PF S+ +Y+KI+ G+ P LS
Sbjct: 183 PEVLNDRGYDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFNCP-PWLSLG 241
Query: 553 GRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTS 612
+ +L+ NP R + F D +W +KP + E D S
Sbjct: 242 AMKLITRILDPNPMTR---------VTPQEVFED-EW-------FKKDYKPPVFEERDDS 284
Query: 613 NFD 615
N D
Sbjct: 285 NMD 287
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 150 bits (379), Expect = 7e-36
Identities = 93/294 (31%), Positives = 155/294 (52%), Gaps = 19/294 (6%)
Query: 322 PQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
P D+ ++G G+F +V + K + + YA+KVL KK IVK+N++ + ER+ ++R
Sbjct: 51 PADYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRL- 109
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
P I L +FQ LY V + GEL +++K E+ +FY AE++ ++EY
Sbjct: 110 -NGFPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEY 168
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSK---------ADLKDRTNTFCGTTEYLA 492
+H I++RDLKPENIL D N ++ + DFG +K D ++F GT EY+A
Sbjct: 169 MHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVA 228
Query: 493 PELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPE 552
PELL + +K D W+ ++++M G PF S+ +++KI + + P+ +L P+
Sbjct: 229 PELLSRQV-VSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPK-LLPPD 286
Query: 553 GRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPP--PFKPH 604
L P R ++++ PFF I W+ + + PP F+P+
Sbjct: 287 IVPLFSHLFRIQPSDR----STTQQIKQFPFFATITWDNLWTQDPPPMQSFRPN 336
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 150 bits (379), Expect = 7e-36
Identities = 91/256 (35%), Positives = 137/256 (52%), Gaps = 7/256 (2%)
Query: 320 YGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVR 379
+ P+DFE+ LG+G FG+VY R++ + + AMKV+ K+ + K + E I R
Sbjct: 48 WSPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSR 107
Query: 380 TASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQ--KEGRFTEDRAKFYIAELVL 437
P I+ L F + +YL + S GELF HL+ RF E R+ Y ++
Sbjct: 108 L---KHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVAN 164
Query: 438 ALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLM 497
AL Y H N++++RDLKPENILL + ++ L DFG S ++ T CGT +YL PE ++
Sbjct: 165 ALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLPPE-MV 223
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
D Y VD W LG+L +E G PF ++ + Y KI ++ +P LS + +
Sbjct: 224 DGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSH-LSKGCKELI 282
Query: 558 KGLLNRNPKHRLGAID 573
GLL + K R+ +D
Sbjct: 283 GGLLRKESKGRITLVD 298
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 150 bits (378), Expect = 9e-36
Identities = 94/279 (33%), Positives = 149/279 (52%), Gaps = 17/279 (6%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
++Q P + V R+LG GT+ V + +T ++YA K+++KK++ KK + +
Sbjct: 23 QKQLLPCKYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDF---VKNEIA 79
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
+++ S P I+ L F+T +LYL+T+ +GGELF + +G F E A +
Sbjct: 80 ILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTT 139
Query: 437 LALEYLHDNDIVYRDLKPENILL---DANGNIALCDFGLS---KADLKDRTNTFCGTTEY 490
A++YLHDN IV+RDLKPEN+L D N ++ + DFGLS + T CGT EY
Sbjct: 140 SAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEY 199
Query: 491 LAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV-- 548
+APE+ TGY K VD W++GV+ + + G++PF ++ + I + F
Sbjct: 200 MAPEVFR-RTGYGKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWS 258
Query: 549 -LSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFND 586
+S + F+K L +P RL A D HPF ++
Sbjct: 259 GISETAKDFIKKCLENDPSKRLTAAD----ALKHPFLSE 293
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 150 bits (378), Expect = 9e-36
Identities = 108/355 (30%), Positives = 183/355 (51%), Gaps = 33/355 (9%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI--LVRTAS 382
+E+ RLLGKGTFG+VY ++ T A+K+++K + ++ + E +I LVR
Sbjct: 15 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVR--- 71
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
P IV LK T T ++ + +++ GGELF + K G+ ED A+ Y +L+ A+++
Sbjct: 72 --HPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVK-GKLKEDSARKYFQQLISAVDFC 128
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLS---KADLKD-RTNTFCGTTEYLAPELLMD 498
H + +RDLKPEN+L+D NG++ + DFGLS + L+D +T CGT Y+APE+L
Sbjct: 129 HSRGVSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRK 188
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVK 558
+ D WS G++++ + G+ PF + KMY+KI + ++P SPE + +
Sbjct: 189 KGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYP-PWFSPESKRLIS 247
Query: 559 GLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEF 618
LL +P R+ + P+F +K I P + I E + N + E
Sbjct: 248 KLLVVDPNKRISI----PAIMRTPWF---------RKNINSPIE-FKIDELEIQNVEDE- 292
Query: 619 TQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNNRKFLQNSY 673
T T+ TP+SP F F F+ + ++ + +++ L++ +
Sbjct: 293 --TPTTTATTATTTTTPVSPKF---FNAFEFISSMSSGFDLSSLFESKRKLRSMF 342
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 149 bits (376), Expect = 1e-35
Identities = 93/279 (33%), Positives = 152/279 (54%), Gaps = 14/279 (5%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++++ R LG G+FG+V T A+K+L+++ I K E+ + ++R
Sbjct: 18 NYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKI-KNMEMEEKVRREIKILRLFMH 76
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
P I+ L +TPTD+YLV ++++ GELF ++ ++GR ED A+ + +++ +EY H
Sbjct: 77 --PHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 134
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLMDETG 501
N +V+RDLKPEN+LLD+ N+ + DFGLS ++D T CG+ Y APE++ +
Sbjct: 135 RNMVVHRDLKPENLLLDSKCNVKIADFGLSNI-MRDGHFLKTSCGSPNYAAPEVISGKLY 193
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
VD WS GV+++ + CG PF + +++KI G P LSP R + +L
Sbjct: 194 AGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSH-LSPGARDLIPRML 252
Query: 562 NRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPP 600
+P R+ E+R HP+F R +PPP
Sbjct: 253 VVDPMKRVTI----PEIRQHPWFQA---HLPRYLAVPPP 284
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 148 bits (374), Expect = 3e-35
Identities = 93/268 (34%), Positives = 142/268 (52%), Gaps = 9/268 (3%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
+K +DFE+ R LGKG FG VY R+K + I A+KVL K + K + H + R
Sbjct: 123 QKEAVALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG-VEHQL-RRE 180
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
+ +++ + P I+ L F T +YL+ ++ G ++ LQK +F E R +
Sbjct: 181 VEIQSHLRH-PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRI 239
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPEL 495
AL Y H +++RD+KPEN+LL + G + + DFG S R T CGT +YL PE+
Sbjct: 240 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 299
Query: 496 LMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRS 555
+ + + + VD WSLGVL +E G PF A+ Q+ Y++I+ + FP D ++ R
Sbjct: 300 I-EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFP-DFVTEGARD 357
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPF 583
+ LL NP R RE+ HP+
Sbjct: 358 LISRLLKHNPSQRPML----REVLEHPW 381
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 148 bits (374), Expect = 3e-35
Identities = 92/249 (36%), Positives = 139/249 (54%), Gaps = 9/249 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ +LLG GTF +VY + + A+KV+ K+ I+K +AH E +IL R
Sbjct: 74 YELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRH-- 131
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P+IV L T + +Y V +++ GGELF + K GR E+ A+ Y +L+ ++ + H
Sbjct: 132 -PYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAK-GRLPEETARRYFQQLISSVSFCHG 189
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR----TNTFCGTTEYLAPELLMDET 500
+ +RDLKPEN+LLD GN+ + DFGLS + R +TFCGT Y+APE+L +
Sbjct: 190 RGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKG 249
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
D WS GV++F + G PF+ + MY+KI G+ + PR S R + L
Sbjct: 250 YDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTR-L 308
Query: 561 LNRNPKHRL 569
L+ NP R+
Sbjct: 309 LDTNPDTRI 317
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 148 bits (373), Expect = 3e-35
Identities = 88/278 (31%), Positives = 154/278 (54%), Gaps = 10/278 (3%)
Query: 307 LIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNE 366
+++ + ++++ DF++ + LG+G FG VY R+K + I A+KVL K + ++++
Sbjct: 1 MLYQAASEAAQKRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQL-QQSQ 59
Query: 367 IAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTED 426
+ H + R + +++ + P I+ L F +YL+ ++ GEL+ LQK F+E
Sbjct: 60 VEHQL-RREVEIQSHLRH-PNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSER 117
Query: 427 RAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCG 486
RA Y+A L AL Y H +++RD+KPEN+L+ A G + + DFG S +R T CG
Sbjct: 118 RAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWS-VHTFNRRRTMCG 176
Query: 487 TTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF-P 545
T +YL PE +++ + VD WSLG+L +E G PF A ++ + Y++I +KF P
Sbjct: 177 TLDYLPPE-MVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPP 235
Query: 546 RDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPF 583
+ ++S + + +L + RL +L HP+
Sbjct: 236 KPIVSSSAKDLISQMLVKESTQRLAL----HKLLEHPW 269
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 147 bits (372), Expect = 4e-35
Identities = 95/249 (38%), Positives = 136/249 (54%), Gaps = 9/249 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ RLLG GTF +VY R T + AMKV+ K+ +VK + +R I V K
Sbjct: 24 YELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQI--KREISVMRMVKH 81
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L + + +Y + + GGELF + K GR ED A+ Y +L+ A+++ H
Sbjct: 82 -PNIVELHEVMASKSKIYFAMELVRGGELFAKVAK-GRLREDVARVYFQQLISAVDFCHS 139
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLS--KADLKD--RTNTFCGTTEYLAPELLMDET 500
+ +RDLKPEN+LLD GN+ + DFGLS LK +T CGT Y+APE+++ +
Sbjct: 140 RGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKG 199
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
D WS GV++F + G+ PF + MY+KI G K P LS + R V L
Sbjct: 200 YDGAKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCP-GWLSSDARRLVTKL 258
Query: 561 LNRNPKHRL 569
L+ NP R+
Sbjct: 259 LDPNPNTRI 267
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 147 bits (371), Expect = 6e-35
Identities = 90/256 (35%), Positives = 140/256 (54%), Gaps = 8/256 (3%)
Query: 316 KKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
K R+ G +EV R +G+GTF +V R DT A+K+++K I+K + E +
Sbjct: 4 KMRRVGK--YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREIS 61
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
I+ P IV L +P+ +Y+V +F++GGELF + +GR E ++ Y +L
Sbjct: 62 IMKIVRH---PNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQL 118
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAP 493
V A+ + H + +RDLKPEN+LLD NGN+ + DFGLS + + T CGT Y+AP
Sbjct: 119 VDAVAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAP 178
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
E+L + D WS GV++F + G+ PF +D +Y+KI + P S E
Sbjct: 179 EVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCP-PWFSAEV 237
Query: 554 RSFVKGLLNRNPKHRL 569
+ + +L+ NPK R+
Sbjct: 238 KFLIHRILDPNPKTRI 253
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 147 bits (371), Expect = 6e-35
Identities = 93/249 (37%), Positives = 141/249 (56%), Gaps = 8/249 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ RLLGKGTF +VY ++ A+KV++K ++K+ + I +R I + +
Sbjct: 12 YEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQI-KREISIMKLVRH 70
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV LK T T ++ V +F+ GGELF + K G+ ED A+ Y +L+ A++Y H
Sbjct: 71 -PNIVELKEVMATKTKIFFVMEFVKGGELFCKISK-GKLHEDAARRYFQQLISAVDYCHS 128
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLS---KADLKD-RTNTFCGTTEYLAPELLMDET 500
+ +RDLKPEN+LLD NG++ + DFGLS + L+D +T CGT Y+APE+L +
Sbjct: 129 RGVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKG 188
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
D WS GV+++ + G PF + MY+KI +FP SPE R + L
Sbjct: 189 YDGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFP-PWFSPEARRLISKL 247
Query: 561 LNRNPKHRL 569
L +P R+
Sbjct: 248 LVVDPDRRI 256
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 147 bits (371), Expect = 6e-35
Identities = 84/254 (33%), Positives = 145/254 (57%), Gaps = 6/254 (2%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
++++ DF++ + LG+G FG VY R+K + + A+KVL K + +++++ H + R +
Sbjct: 23 QKRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQL-QQSQVEHQL-RREV 80
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
+++ + P I+ L F +YL+ ++ + GEL+ LQK F+E RA Y+A L
Sbjct: 81 EIQSHLRH-PNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLA 139
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELL 496
AL Y H +++RD+KPEN+L+ A G + + DFG S +R T CGT +YL PE +
Sbjct: 140 RALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWS-VHTFNRRRTMCGTLDYLPPE-M 197
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF-PRDVLSPEGRS 555
++ + VD WSLG+L +E G PF A ++ Y++I +KF P+ ++S +
Sbjct: 198 VESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKD 257
Query: 556 FVKGLLNRNPKHRL 569
+ +L + RL
Sbjct: 258 LISQMLVKESSQRL 271
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 147 bits (370), Expect = 7e-35
Identities = 93/253 (36%), Positives = 140/253 (54%), Gaps = 17/253 (6%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVK---KNEIAHTIGERNILVRTA 381
+EV + LG+GTF +VY R T A+KV+ K+ I+K +I I +L
Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLL---- 67
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
P IV L T + +Y V + + GGELF + G+ ED A+ Y +LV A+++
Sbjct: 68 --RHPNIVELHEVMATKSKIYFVMEHVKGGELF-NKVSTGKLREDVARKYFQQLVRAVDF 124
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR----TNTFCGTTEYLAPELLM 497
H + +RDLKPEN+LLD +GN+ + DFGLS R +T CGT Y+APE++
Sbjct: 125 CHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVI- 183
Query: 498 DETGYTKM-VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSF 556
GY D WS GV++F + G+ PF S+ ++Y+KI +VKFP + L+P +
Sbjct: 184 SRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFP-NWLAPGAKRL 242
Query: 557 VKGLLNRNPKHRL 569
+K +L+ NP R+
Sbjct: 243 LKRILDPNPNTRV 255
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 146 bits (369), Expect = 1e-34
Identities = 93/249 (37%), Positives = 134/249 (53%), Gaps = 9/249 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ +LLG G+F +VY R + A+KV+ K+ IVK H E +IL R
Sbjct: 57 YEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVRH-- 114
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P+IV L T T +Y+V +++ GGEL+ + GR E A+ Y +L+ ++ + H
Sbjct: 115 -PYIVHLLEVMATKTKIYIVMEYVRGGELY-NTVARGRLREGTARRYFQQLISSVAFCHS 172
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLS--KADLKDR--TNTFCGTTEYLAPELLMDET 500
+ +RDLK EN+LLD GN+ + DFGLS LK TFCGT YLAPE+L +
Sbjct: 173 RGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKG 232
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
D WS GV++F + G+ PF + MY KI G+ K P+ SPE V +
Sbjct: 233 YEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPK-WFSPELARLVTRM 291
Query: 561 LNRNPKHRL 569
L+ NP R+
Sbjct: 292 LDTNPDTRI 300
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 146 bits (369), Expect = 1e-34
Identities = 97/262 (37%), Positives = 149/262 (56%), Gaps = 15/262 (5%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+ V ++G+G+FG VY+ +KD ++ A+KV+SK+ K E+ + E +I R
Sbjct: 4 YAVSSMVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATK-ELKNLRRECDIQARL---K 59
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P ++ + SF++ TDL++VT+F +L +L G E+ A+ LV AL YLH
Sbjct: 60 HPHVIEMIESFESKTDLFVVTEFALM-DLHRYLSYNGAMGEEPARRVTGHLVSALYYLHS 118
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFC---GTTEYLAPELLMDETG 501
N I++RDLKP+N+LLD N + LCDFGL++ ++ T+ GT Y+APELL ++
Sbjct: 119 NRILHRDLKPQNVLLDKNMHAKLCDFGLAR-NMTLGTHVLTSIKGTPLYMAPELLAEQP- 176
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y D WSLG + +E G PF AS + + I VK+P L+ E RSF++GLL
Sbjct: 177 YDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWP-STLTSECRSFLQGLL 235
Query: 562 NRNPKHRLGAIDDGRELRAHPF 583
++P R+ +L HPF
Sbjct: 236 EKDPGLRI----SWTQLLCHPF 253
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 145 bits (367), Expect = 2e-34
Identities = 93/305 (30%), Positives = 164/305 (53%), Gaps = 28/305 (9%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRT 380
G +DF+ LG G++ V +D+ + YA+KVLSK+ ++++ ++ + E+ L +
Sbjct: 121 GIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKL 180
Query: 381 ASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALE 440
F L F+FQ LY + ++ G+ ++K G E A++Y ++++ A++
Sbjct: 181 NGTKGIF--KLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVD 238
Query: 441 YLHDNDIVYRDLKPENILLDANGNIALCDFGLSKA---------------DLKDRTNTFC 485
LH+ I++RD+KPENILLD N + L DFG +K DL ++ +F
Sbjct: 239 SLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFV 298
Query: 486 GTTEYLAPELLMDETGYT-KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF 544
GT EY++PELL D YT D W+ G ++++M G PF A++ +QK+ K+++
Sbjct: 299 GTAEYVSPELLND--NYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVM--KIQY 354
Query: 545 PRDVLSPE-GRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWE-AVRQKKIPPPFK 602
P+ + VK LL R+P RL ++++AH FF+++++E PP +
Sbjct: 355 AFTAGFPQIVKDLVKKLLVRDPNDRLTI----KQIKAHLFFHEVNFEDGSVWDDNPPEIQ 410
Query: 603 PHLIS 607
P+ I+
Sbjct: 411 PYKIN 415
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 145 bits (365), Expect = 3e-34
Identities = 71/163 (43%), Positives = 109/163 (66%), Gaps = 3/163 (1%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHT 370
++ ++ + +DF ++++GKG FG+V V+KKDT +IYAMK L K + KK+++AH
Sbjct: 338 QFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHV 397
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
ER++L A SP++V L +SFQ LYL+ +F+ GG+L L + FTED +F
Sbjct: 398 KAERDVL---AGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRF 454
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS 473
Y+AE +LA+E +H ++RD+KP+NIL+D G+I L DFGLS
Sbjct: 455 YMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 497
Score = 89.0 bits (219), Expect = 2e-17
Identities = 49/132 (37%), Positives = 77/132 (58%), Gaps = 7/132 (5%)
Query: 486 GTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VK 543
GT +Y+APE+ + + GY + D+WSLG +++E GW PF + Q+ Y+KI + ++
Sbjct: 573 GTPDYIAPEIFLYQ-GYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 631
Query: 544 FPRDV-LSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFK 602
FP D+ +S E ++ LL + RLG E+++HPFF +DW +RQ + P+
Sbjct: 632 FPDDIHISYEAEDLIRRLLT-HADQRLGRHGGADEIKSHPFFRGVDWNTIRQ--VEAPYI 688
Query: 603 PHLISETDTSNF 614
P L S TDT F
Sbjct: 689 PKLSSITDTRFF 700
>At2g34650 [R] KOG0610 Putative serine/threonine protein kinase
Length = 438
Score = 145 bits (365), Expect = 3e-34
Identities = 107/357 (29%), Positives = 164/357 (44%), Gaps = 70/357 (19%)
Query: 311 EYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVR-----KKDTMRIYAMKVLSKKVIVKKN 365
E KK+ +DF ++R +G G G VY R ++ +AMKV+ K+ + K
Sbjct: 61 EIRRRKKQGLTFRDFRLMRRIGAGDIGTVYLCRLAGDEEESRSSYFAMKVVDKEALALKK 120
Query: 366 EIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGEL--FWHLQKEGRF 423
++ E+ IL PF+ L F+ +V ++ SGG+L H Q RF
Sbjct: 121 KMHRAEMEKTILKML---DHPFLPTLYAEFEASHFSCIVMEYCSGGDLHSLRHRQPHRRF 177
Query: 424 TEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS---------- 473
+ A+FY AE+++ALEYLH I+YRDLKPENIL+ ++G+I L DF LS
Sbjct: 178 SLSSARFYAAEVLVALEYLHMLGIIYRDLKPENILVRSDGHIMLSDFDLSLCSDSIAAVE 237
Query: 474 -------------------------------KADLKDRTNTF------------CGTTEY 490
K + T F GT EY
Sbjct: 238 SSSSSPENQQLRSPRRFTRLARLFQRVLRSKKVQTLEPTRLFVAEPVTARSGSFVGTHEY 297
Query: 491 LAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRD--- 547
+APE+ + + VD+W+ GV ++EM G +PF A N + + I ++ FP D
Sbjct: 298 VAPEVASGGS-HGNAVDWWAFGVFLYEMIYGKTPFVAPTNDVILRNIVKRQLSFPTDSPA 356
Query: 548 -VLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKP 603
+ R+ + GLLN++P RLG+ E++ HPFF +++ +R + PP P
Sbjct: 357 TMFELHARNLISGLLNKDPTKRLGSRRGAAEVKVHPFFKGLNFALIR--TLTPPEIP 411
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 144 bits (364), Expect = 4e-34
Identities = 85/247 (34%), Positives = 136/247 (54%), Gaps = 6/247 (2%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ R LG+GTF +V R + A+KV+ K+ ++K IA +R I K
Sbjct: 31 YELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQI--KREISTMKLIKH 88
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P ++ + + T +Y V +F++GGELF + GR ED A+ Y +L+ A++Y H
Sbjct: 89 -PNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHS 147
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKD--RTNTFCGTTEYLAPELLMDETGY 502
+ +RDLKPEN+LLDANG + + DFGLS ++ +T CGT Y+APE++ ++
Sbjct: 148 RGVYHRDLKPENLLLDANGALKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVINNKGYD 207
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN 562
D WS GV++F + G+ PF S+ +Y+KI + P S + +K +L+
Sbjct: 208 GAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCP-PWFSASAKKLIKRILD 266
Query: 563 RNPKHRL 569
NP R+
Sbjct: 267 PNPATRI 273
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 144 bits (362), Expect = 6e-34
Identities = 88/246 (35%), Positives = 142/246 (56%), Gaps = 13/246 (5%)
Query: 330 LLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIV 389
+LG G F +V K T ++ A+K ++K+ + K E I V K P IV
Sbjct: 25 VLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSM----ENEIAVLHKIKH-PNIV 79
Query: 390 GLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVY 449
L +++ LYL+ +SGGELF + ++G +TE A I +++ A++YLHD IV+
Sbjct: 80 ALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVH 139
Query: 450 RDLKPENIL---LDANGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLMDETGYTKM 505
RDLKPEN+L LD + I + DFGLSK D +T CGT Y+APE+L + Y+K
Sbjct: 140 RDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKP-YSKA 198
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR---DVLSPEGRSFVKGLLN 562
VD WS+GV+ + + CG+ PF+ ++ K++++I + +F D +S + F++ L+
Sbjct: 199 VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLME 258
Query: 563 RNPKHR 568
++P+ R
Sbjct: 259 KDPEKR 264
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 144 bits (362), Expect = 6e-34
Identities = 97/295 (32%), Positives = 157/295 (52%), Gaps = 22/295 (7%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E R++G G F V + R ++T + YAMK++ K + K ++ + IL+ S S
Sbjct: 284 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMV----DSEILI-IQSLS 338
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L ++T ++YL+ +++ GG+LF + + +F E A I +L AL ++HD
Sbjct: 339 HPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHD 398
Query: 445 NDIVYRDLKPENILL----DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDET 500
IV+RDLKPEN+L+ D + + L DFGL+K ++ T CGT Y+APE+L E
Sbjct: 399 KSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRP-IFTVCGTPTYVAPEIL-SEK 456
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFA--SDNQKMYQKIAFGKVKFPR---DVLSPEGRS 555
GY VD W+ GV+++ + CG+ PF + D +++ I G +F D +S +
Sbjct: 457 GYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKD 516
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDW--EAVRQKKIPPPFKPHLISE 608
V LL +PK R A ++ HP+ RQK++ P + H S+
Sbjct: 517 LVSRLLVVDPKKRYTA----HQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQ 567
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 142 bits (358), Expect = 2e-33
Identities = 88/256 (34%), Positives = 135/256 (52%), Gaps = 5/256 (1%)
Query: 313 TSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIG 372
T K ++ DFE+ R LGKG FG VY R K A+KVL K ++ + H +
Sbjct: 18 TPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGG-VEHQL- 75
Query: 373 ERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYI 432
ER I +++ + P I+ L F +YLV ++ GGE++ L RF+E A Y+
Sbjct: 76 EREIEIQS-HLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYM 134
Query: 433 AELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLA 492
E+ AL Y H ++++RD+KPEN+L+ + G + + DFG S ++ T CGT +YL
Sbjct: 135 YEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLP 194
Query: 493 PELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPE 552
PE +++ ++ VD W++GVL +E G PF D K Y I + +P D +
Sbjct: 195 PE-MVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYP-DSVKKG 252
Query: 553 GRSFVKGLLNRNPKHR 568
R + LL +PK R
Sbjct: 253 ARDLIGRLLVVDPKAR 268
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 142 bits (358), Expect = 2e-33
Identities = 87/251 (34%), Positives = 137/251 (53%), Gaps = 13/251 (5%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI--LVRTAS 382
+E+ RLLG+GTF +VY R T A+KV+ K+ + K I E ++ LVR
Sbjct: 12 YELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVR--- 68
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
P +V L + T +Y +++ GGELF + K G+ E+ A+ Y +L+ A++Y
Sbjct: 69 --HPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSK-GKLKENIARKYFQQLIGAIDYC 125
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLS----KADLKDRTNTFCGTTEYLAPELLMD 498
H + +RDLKPEN+LLD NG++ + DFGLS +T CGT Y+APE++
Sbjct: 126 HSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGK 185
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVK 558
+ D WS GV+++ + G+ PF + +MY+KI G+ K P + PE + +
Sbjct: 186 KGYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCP-NWFPPEVKKLLS 244
Query: 559 GLLNRNPKHRL 569
+L+ NP R+
Sbjct: 245 RILDPNPNSRI 255
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 142 bits (358), Expect = 2e-33
Identities = 81/249 (32%), Positives = 137/249 (54%), Gaps = 10/249 (4%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI--LVRTAS 382
+E+ R +G+GTF +V + +T AMK++ + I+K+ + E +I LVR
Sbjct: 9 YELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVR--- 65
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
P +V L + T +Y++ ++++GGELF + + GR +E A+ Y +L+ ++Y
Sbjct: 66 --HPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYC 123
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRT--NTFCGTTEYLAPELLMDET 500
H + +RDLKPEN+LLD+ GN+ + DFGLS + T T CGT Y+APE+L +
Sbjct: 124 HSKGVYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKG 183
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
+ D WS GV+++ + G+ PF D +Y KI + P + +S + +
Sbjct: 184 YNGAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCP-SYFALGAKSLINRI 242
Query: 561 LNRNPKHRL 569
L+ NP+ R+
Sbjct: 243 LDPNPETRI 251
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 142 bits (358), Expect = 2e-33
Identities = 99/354 (27%), Positives = 169/354 (46%), Gaps = 34/354 (9%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+ + RLLG G F +VY + T A+KV+ K + K+ + I ER I V +
Sbjct: 15 YNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQI-EREIAVMRLLRH 73
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P +V L+ T ++ V ++++GGELF + ++G+ ED A+ Y +L+ A+++ H
Sbjct: 74 -PNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHS 132
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLS-----------KADLKDRTNTFCGTTEYLAP 493
+ +RD+KPEN+LLD G++ + DFGLS + D +T CGT Y+AP
Sbjct: 133 RGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAP 192
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEG 553
E+L ++ M D WS G++++ + G+ PF + +Y KI + +FP S E
Sbjct: 193 EVLRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFP-PWFSLES 251
Query: 554 RSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSN 613
+ + LL +P+ R+ E++ P+F +K P I ET S
Sbjct: 252 KELLSRLLVPDPEQRISM----SEIKMIPWF----------RKNFTPSVAFSIDETIPSP 297
Query: 614 FDPEFTQTSTSFMNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNNRK 667
+P + K+ A+P S F F F+ + +N + ++
Sbjct: 298 PEPPTKKKKKDLNEKEDDGASPRS------FNAFQFITSMSSGFDLSNLFEIKR 345
>Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 147
Score = 142 bits (357), Expect = 2e-33
Identities = 74/150 (49%), Positives = 101/150 (67%), Gaps = 6/150 (4%)
Query: 360 VIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQK 419
++ + AHT E NIL PFIV L ++FQT LYL+ +++SGGELF L++
Sbjct: 2 IVRNAKDTAHTKAEWNILEEVRH---PFIVDLTYAFQTGGKLYLILEYLSGGELFMQLER 58
Query: 420 EGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKD 479
EG F ED A FY+AE+ +AL +LH I+YRDLKPENI+L+ G++ L DFGL K + D
Sbjct: 59 EGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIILNHQGHMKLTDFGLRKESIHD 118
Query: 480 R--TNTFCGTTEYLAPELLMDETGYTKMVD 507
T+TFCGT EY+APE+LM +G+ + VD
Sbjct: 119 GTVTHTFCGTIEYMAPEILM-RSGHNRAVD 147
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 141 bits (355), Expect = 4e-33
Identities = 92/250 (36%), Positives = 144/250 (56%), Gaps = 11/250 (4%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
++V RLLG+GTF +VY R T + A+K++ K+ ++K I +R I V ++
Sbjct: 12 YDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQI--KREISVMRIARH 69
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P +V L T T +Y V ++ GGELF + K G+ +D A Y +L+ A+++ H
Sbjct: 70 -PNVVELYEVMATKTRIYFVMEYCKGGELFNKVAK-GKLRDDVAWKYFYQLINAVDFCHS 127
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDR---TNTFCGTTEYLAPELLMDET 500
++ +RD+KPEN+LLD N N+ + DFGLS AD K + +T CGT Y+APE++ +
Sbjct: 128 REVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVI-NRK 186
Query: 501 GYT-KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
GY D WS GV++F + G+ PF S+ +MY+KI K P +PE R +
Sbjct: 187 GYDGTKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAP-SWFAPEVRRLLCK 245
Query: 560 LLNRNPKHRL 569
+L+ NP+ R+
Sbjct: 246 MLDPNPETRI 255
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 140 bits (354), Expect = 5e-33
Identities = 78/245 (31%), Positives = 137/245 (55%), Gaps = 6/245 (2%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ LGKGT+G+V + ++ + R+ A+K + K I + ++ H E I+ +S +
Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIM---SSLN 111
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ + F+ + ++ ++ S GEL+ ++ + R +E + + ++V A+ Y H
Sbjct: 112 HPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHK 171
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPELLMDETGYT 503
N +V+RDLK ENILLD N NI + DFGLS KD+ TFCG+ Y +PE++
Sbjct: 172 NGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRG 231
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
VD W+LGVL++ + G PF D++ + ++I+ G+ + P + R ++ +L
Sbjct: 232 PEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ--PSDARGLIRWMLMV 289
Query: 564 NPKHR 568
NP R
Sbjct: 290 NPDRR 294
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 140 bits (353), Expect = 7e-33
Identities = 95/253 (37%), Positives = 147/253 (57%), Gaps = 17/253 (6%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
FEV LG+G VY+ ++K T + YA+KVL KK + KK I T E +L+R S
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVL-KKTVDKK--IVRT--EIGVLLRL---S 97
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ LK F+TPT++ LV + ++GGELF + ++G ++E A + +++ A+ YLH+
Sbjct: 98 HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHE 157
Query: 445 NDIVYRDLKPENILLDA---NGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLMDET 500
N IV+RDLKPEN+L + + + DFGLSK + + T CGT Y APE+L
Sbjct: 158 NGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRG-C 216
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFF-ASDNQKMYQKIAFGKVKFPR---DVLSPEGRSF 556
Y VD WS+G++ + + CG+ PF+ +Q M+++I + F D +S +
Sbjct: 217 AYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDL 276
Query: 557 VKGLLNRNPKHRL 569
V+ L+ +PK RL
Sbjct: 277 VRKLIVLDPKKRL 289
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 139 bits (351), Expect = 1e-32
Identities = 89/270 (32%), Positives = 146/270 (53%), Gaps = 12/270 (4%)
Query: 317 KRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNI 376
KR GP + + LG+G+FG+V T + A+K +S++++ K + H ER I
Sbjct: 28 KRHIGP--YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSD--MHMRVEREI 83
Query: 377 LVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
+ P I+ L TPTD+ +V ++ +GGELF ++ ++ R TED + + +++
Sbjct: 84 SYLKLLRH-PHIIKLYDVITTPTDIVMVIEY-AGGELFDYIVEKKRMTEDEGRRFFQQII 141
Query: 437 LALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPEL 495
A+EY H + IV+RDLKPEN+LLD N N+ + DFGLS T CG+ Y APE+
Sbjct: 142 CAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEV 201
Query: 496 LMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRS 555
+ + VD WS G++++ M G PF +++K+ P D LSP +S
Sbjct: 202 INGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMP-DFLSPGAQS 260
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPFFN 585
++ ++ +P R+ +E+R P+FN
Sbjct: 261 LIRRMIVADPMQRITI----QEIRRDPWFN 286
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 139 bits (349), Expect = 2e-32
Identities = 105/363 (28%), Positives = 179/363 (48%), Gaps = 28/363 (7%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTAS 382
+D+ LG+G F + +Q+ K D+ I+A K ++K I + + E I S
Sbjct: 80 KDYHRGHFLGEGGFARCFQI-KDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQI---HKS 135
Query: 383 KSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYL 442
S P IV F+ +++Y++ + G L L++ TE +F+ ++ A++Y+
Sbjct: 136 MSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYM 195
Query: 443 HDNDIVYRDLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELLMDE- 499
H +++RDLK NI D+N N+ + DFGL+ A+ +R T CGT Y+APE+LM +
Sbjct: 196 HSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKH 255
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRD-VLSPEGRSFVK 558
+G++ VD WSLGV+++ + G PF A D +Y++I FPRD +S EG+ ++
Sbjct: 256 SGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIR 315
Query: 559 GLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDPEF 618
+L+ +P R P +I + PP ++SE PE
Sbjct: 316 DILSLDPIER-------------PSLTEIMDYVWFRGTFPPSIPSTVMSEAPNFEDIPE- 361
Query: 619 TQTSTSF---MNKQPIAATPLSPAMQAKFVGFTFVDESAIDEHYNNAYNNRKFLQNSYFM 675
Q+ +F M K + + S +Q + + +S+ID+ + NR FL +S +
Sbjct: 362 EQSLVNFKDCMEKSLLLESMSSDKIQRQKRDYISSIKSSIDK-LEEYHQNRPFLPHS--L 418
Query: 676 EPG 678
PG
Sbjct: 419 SPG 421
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 139 bits (349), Expect = 2e-32
Identities = 90/249 (36%), Positives = 137/249 (54%), Gaps = 9/249 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+EV +L+G G F +VY R T + A+KV+SK+ + K + E I+ R
Sbjct: 22 YEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQREIAIMHRLRH-- 79
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L T + ++ V +F GGELF + K GRF ED ++ Y +L+ A+ Y H
Sbjct: 80 -PSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSK-GRFCEDLSRRYFQQLISAVGYCHS 137
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR----TNTFCGTTEYLAPELLMDET 500
I +RDLKPEN+LLD ++ + DFGLS + R +T CGT Y+APE+L +
Sbjct: 138 RGIFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKG 197
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
+D WS G+++F + G+ PF + MY+KI G+ + P+ SP+ R + L
Sbjct: 198 YDGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPK-WTSPDLRRLLTRL 256
Query: 561 LNRNPKHRL 569
L+ NP+ R+
Sbjct: 257 LDTNPQTRI 265
>SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 338
Score = 138 bits (348), Expect = 3e-32
Identities = 97/301 (32%), Positives = 153/301 (50%), Gaps = 31/301 (10%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGE-RNILVRTASK 383
F++ ++GKG++ V+ V+ + T + +A+K ++KK K +E H I + RN ++ S
Sbjct: 30 FKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKK---KHDE--HKIKKLRNEVLLLQSL 84
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+ P + F+ T +YLVTD M GG+L +H+ + +F E + ++ ELV AL Y+H
Sbjct: 85 NHPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHISQR-KFNESVIRIWMVELVSALIYIH 143
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGL-------SKADLKDRTNTFCGTTEYLAPELL 496
+++RD+KP+NILLD G+ L DF + S + T GT Y+APE L
Sbjct: 144 SKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPVYMAPETL 203
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPF---------FASDNQKMYQKIAFGK-VKFPR 546
+ Y K D+WSLG+ +E PF AS+ +K + R
Sbjct: 204 IHAVSY-KESDWWSLGITFYECLFQVRPFPNHLLINWIRASEEEKASSADRLSSALHISR 262
Query: 547 D----VLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFK 602
D +S + RS V L + K RLG ++L+ HPFF I E V + + P F+
Sbjct: 263 DKKLTTISKDARSAVMAFLEMDIKKRLG--HSSKKLQTHPFFCSISLETVSKGNLTPIFR 320
Query: 603 P 603
P
Sbjct: 321 P 321
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 138 bits (348), Expect = 3e-32
Identities = 91/263 (34%), Positives = 146/263 (54%), Gaps = 14/263 (5%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
FE+ RLLG+G FGQV+ R+++ I A+K++ K I + E A I R I + + K
Sbjct: 10 FEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEI-QTVETARQI-RREIEIHSNLKH 67
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQ-KEGRFTEDRAKFYIAELVLALEYLH 443
P I+ + F ++YL+ ++ GE F L + G+F E YI +++LAL Y+
Sbjct: 68 -PNILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSLYIRQVMLALTYMK 126
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDETGYT 503
+ ++++RD+KPEN+LL ++ + + DFG + + R TFCGT EYLAPE++ ++ +
Sbjct: 127 ECNVIHRDIKPENLLLGSDNQLKIADFGWAVYNADKRRMTFCGTMEYLAPEMVNNDI-HD 185
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKM---YQKIAFGKVKFPRDVLSPEGRSFVKGL 560
+D W LG+L +E G +P F S N+ M Y+KI K P + +S F+ L
Sbjct: 186 SGIDLWCLGILTYEFLMGKTP-FESKNRNMREAYKKINSLKYTIP-ETISSNASDFISRL 243
Query: 561 LNRNPKHRLGAIDDGRELRAHPF 583
L +P R+ + E HPF
Sbjct: 244 LVLSPGDRM----ELTEALNHPF 262
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 138 bits (347), Expect = 3e-32
Identities = 88/258 (34%), Positives = 145/258 (56%), Gaps = 20/258 (7%)
Query: 329 RLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFI 388
R+LGKG+FG V + K+T +A+K ++K+ K A + ER + + + K I
Sbjct: 120 RILGKGSFGIVIEATDKETETKWAIKKVNKE---KAGSSAVKLLEREVNILKSVKHE-HI 175
Query: 389 VGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIV 448
+ L+ F+TP +YLV + GEL L ++G F+E+ ++ I L A+ YLH+NDIV
Sbjct: 176 IHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIV 235
Query: 449 YRDLKPENILL---------DANGNIALCDFGLS---KADLKDRTNTFCGTTEYLAPELL 496
+RDLK ENI++ + N NI + DFGL+ ++ + CGT Y+APE++
Sbjct: 236 HRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVI 295
Query: 497 MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV---LSPEG 553
Y++ D WS+GV+++ + G PF AS +K+++ I G++ F V +S
Sbjct: 296 -SAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCA 354
Query: 554 RSFVKGLLNRNPKHRLGA 571
+S +K L+ +P HR+ A
Sbjct: 355 KSVLKQLMKVDPAHRITA 372
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 137 bits (346), Expect = 5e-32
Identities = 84/258 (32%), Positives = 140/258 (53%), Gaps = 13/258 (5%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKK-DTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
+ ++ +LG G F +V+ K D ++YA+K + KK + K E E +L +
Sbjct: 20 EKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLEN--EIKVLRKLR 77
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
+ IV L ++ +YLV + ++GGELF + +G +TE A I +++ A+ +
Sbjct: 78 HNN---IVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGF 134
Query: 442 LHDNDIVYRDLKPENILL---DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMD 498
+HDN +V+RDLKPEN+L D + I + DFGLSK + T CGT Y+APE+L
Sbjct: 135 MHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSGVMATACGTPGYVAPEVLQQ 194
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR---DVLSPEGRS 555
+ Y K VD WS+GV+ + + CG+ PF+ + ++ +I G+ +F D +S +
Sbjct: 195 KP-YGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKD 253
Query: 556 FVKGLLNRNPKHRLGAID 573
F+ L+ +P+ R D
Sbjct: 254 FITHLMCCDPEARFTCQD 271
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 137 bits (346), Expect = 5e-32
Identities = 91/271 (33%), Positives = 144/271 (52%), Gaps = 20/271 (7%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
++V R +G G F V + ++ T R YA+K++ K K + E +IL R
Sbjct: 46 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQN--EVSILRRV---K 100
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L PT+LYLV + + GG+LF + ++TE A + L A++YLH
Sbjct: 101 HPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHS 160
Query: 445 NDIVYRDLKPENILL----DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLMDET 500
+IV+RD+KPEN+L+ D + ++ L DFGL+ + T CGT Y+APE++ ET
Sbjct: 161 LNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-VDGPLYTVCGTPTYVAPEIIA-ET 218
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFAS--DNQKMYQKIAFGKVKFPR---DVLSPEGRS 555
GY VD W+ GV+ + + CG+ PF S D + ++ +I G+V FP D +S +
Sbjct: 219 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 278
Query: 556 FVKGLLNRNPKHRLGAIDDGRELRAHPFFND 586
+ +L + R A+ ++ HP+ ND
Sbjct: 279 LITMMLLVDVDQRFSAV----QVLEHPWVND 305
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 137 bits (345), Expect = 6e-32
Identities = 85/250 (34%), Positives = 133/250 (53%), Gaps = 9/250 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ R LG G+F +V+ R T + A+K++ K+ + I E + R +
Sbjct: 21 YELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRL--HN 78
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P ++ + T + +YLV ++ +GGELF L + GR E A+ Y +L AL + H
Sbjct: 79 HPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCHR 138
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTN-----TFCGTTEYLAPELLMDE 499
+ I +RD+KP+N+LLD GN+ + DFGLS A + R+N T CGT Y APE++
Sbjct: 139 DGIAHRDVKPQNLLLDKQGNLKVSDFGLS-ALPEHRSNNGLLHTACGTPAYTAPEVIAQR 197
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
D WS GV +F + G+ PF ++ MY+KI +FP + P RS +
Sbjct: 198 GYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYRFPSWISKP-ARSIIYK 256
Query: 560 LLNRNPKHRL 569
LL+ NP+ R+
Sbjct: 257 LLDPNPETRM 266
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 137 bits (345), Expect = 6e-32
Identities = 83/251 (33%), Positives = 138/251 (54%), Gaps = 22/251 (8%)
Query: 330 LLGKGTFGQVYQVRKKDTM-RIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK----- 383
LLG G F +V KD+ +A+K++ KK + K E E +L R ++
Sbjct: 36 LLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLEN--EIRVLRRFSANHFDGK 93
Query: 384 -------SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELV 436
+ P IV L +++ + +YLV + ++GGELF + ++G +TE A I +++
Sbjct: 94 CLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQIL 153
Query: 437 LALEYLHDNDIVYRDLKPENILL---DANGNIALCDFGLSKADLKDRTNTFCGTTEYLAP 493
A++Y+H+ +V+RDLKPEN+L D + I + DFGLSK + T CGT Y+AP
Sbjct: 154 EAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGYVAP 213
Query: 494 ELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPR---DVLS 550
E+L + Y K VD WS+GV+ + + CG+ PF+ ++ ++ +I G +F D +S
Sbjct: 214 EVLAQKP-YGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEIS 272
Query: 551 PEGRSFVKGLL 561
+ F+K L+
Sbjct: 273 ESAKHFIKNLM 283
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 137 bits (344), Expect = 8e-32
Identities = 81/245 (33%), Positives = 138/245 (56%), Gaps = 7/245 (2%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E L LGKGT+G+V + R+ R+ A+K + K I + ++ H E I+ +S +
Sbjct: 53 YEFLETLGKGTYGKVKKARESSG-RLVAIKSIRKDKIKDEQDLMHIRREIEIM---SSLN 108
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ + F+ + + +V ++ S G+L+ ++ + + +E A+ + ++V A+ Y H
Sbjct: 109 HPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQ 168
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPELLMDETGYT 503
N +V+RDLK ENILLDANGNI + DFGLS + + TFCG+ Y +PE++ +
Sbjct: 169 NRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTG 228
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
VD WSLGVL++ + G PF D++ + ++I+ G + P + ++ LL
Sbjct: 229 PEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPK--PSDACGLIRWLLMV 286
Query: 564 NPKHR 568
NP R
Sbjct: 287 NPTRR 291
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 136 bits (343), Expect = 1e-31
Identities = 92/316 (29%), Positives = 149/316 (47%), Gaps = 48/316 (15%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF L+ +G+G + QV++ R+ T ++A+KVL K + + ++ I E+NIL + +
Sbjct: 68 DFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQE 127
Query: 384 SS--PFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
PF+ L F +Y V + G+L L G F +KF+ +E++ L++
Sbjct: 128 CGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQF 187
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFG---------LSKADLKD------------- 479
LHDN IV+RD+KP+N+L+ +G+I + DFG LS+ D
Sbjct: 188 LHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSGS 247
Query: 480 ----------------RTNTFCGTTEYLAPELLMD-ETGYTKMVDFWSLGVLIFEMCCGW 522
R TF GT Y++PE+L D + G D W LG ++F+ G
Sbjct: 248 PPPTRFYSDEEEENTARRTTFVGTALYVSPEMLADGDVG--PQTDIWGLGCILFQCLAGQ 305
Query: 523 SPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHP 582
PF A + + ++I FP + E + +L R+P R+ +EL AH
Sbjct: 306 PPFRAVNQYHLLKRIQELDFSFP-EGFPEEASEIIAKILVRDPSTRI----TSQELMAHK 360
Query: 583 FFNDIDWEAVRQKKIP 598
FF ++DW + K P
Sbjct: 361 FFENVDWVNIANIKPP 376
>CE29300 [T] KOG0694 Serine/threonine protein kinase
Length = 431
Score = 136 bits (342), Expect = 1e-31
Identities = 95/282 (33%), Positives = 149/282 (52%), Gaps = 14/282 (4%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRK-KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
+ F + R LG+G+FG VY D+ R +A+K+ K+ I+ K + +R ++
Sbjct: 119 KSFVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQV--KREASIQRL 176
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSG--GELFWHLQKEGRFTEDRAKFYIAELVLAL 439
S PFI ++QT T LY + + +G G+LF ++ G +E + AEL A+
Sbjct: 177 LPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAI 236
Query: 440 EYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLM 497
++LH ND++YRD+K EN++LD G+ L DFGL+K LK T T CGT +Y++P++
Sbjct: 237 DFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAK-KLKQGSSTGTICGTLQYMSPDVAS 295
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
T Y+ VD+WSLGVL+ + G P + + + + F P S E + +
Sbjct: 296 GGT-YSHYVDWWSLGVLLHILLTGIYP-YPNSEATHHANLKFIDYSTPIG-CSREFANLM 352
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPP 599
+L + HRL + L AHPFF ID+ + QK P
Sbjct: 353 DRMLAVSITHRLCSF---TVLHAHPFFRSIDFSKLEQKDYTP 391
>CE29299 [T] KOG0694 Serine/threonine protein kinase
Length = 436
Score = 136 bits (342), Expect = 1e-31
Identities = 95/282 (33%), Positives = 149/282 (52%), Gaps = 14/282 (4%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRK-KDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
+ F + R LG+G+FG VY D+ R +A+K+ K+ I+ K + +R ++
Sbjct: 119 KSFVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQV--KREASIQRL 176
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSG--GELFWHLQKEGRFTEDRAKFYIAELVLAL 439
S PFI ++QT T LY + + +G G+LF ++ G +E + AEL A+
Sbjct: 177 LPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAI 236
Query: 440 EYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLM 497
++LH ND++YRD+K EN++LD G+ L DFGL+K LK T T CGT +Y++P++
Sbjct: 237 DFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAK-KLKQGSSTGTICGTLQYMSPDVAS 295
Query: 498 DETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFV 557
T Y+ VD+WSLGVL+ + G P + + + + F P S E + +
Sbjct: 296 GGT-YSHYVDWWSLGVLLHILLTGIYP-YPNSEATHHANLKFIDYSTPIG-CSREFANLM 352
Query: 558 KGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPP 599
+L + HRL + L AHPFF ID+ + QK P
Sbjct: 353 DRMLAVSITHRLCSF---TVLHAHPFFRSIDFSKLEQKDYTP 391
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 136 bits (342), Expect = 1e-31
Identities = 87/265 (32%), Positives = 140/265 (52%), Gaps = 12/265 (4%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++ + + LG G+F +V T A+K+L++ I KN +R I +
Sbjct: 18 NYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKI--KNMGIEIKVQREIKI-LRFL 74
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
P I+ +TP D+Y+V +++ GELF ++ ++G+ ED A+ +++ +EY H
Sbjct: 75 MHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCH 134
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLMDETG 501
N IV+RDLKPEN+LLD+ NI + DFGLS + D T CG+ Y APE++ +
Sbjct: 135 RNMIVHRDLKPENVLLDSQCNIKIVDFGLSNV-MHDGHFLKTSCGSPNYAAPEVISGKP- 192
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
Y VD WS GV+++ + CG PF + +++KI G P LS R + +L
Sbjct: 193 YGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNH-LSHFARDLIPRML 251
Query: 562 NRNPKHRLGAIDDGRELRAHPFFND 586
+P R+ E+R HP+FN+
Sbjct: 252 MVDPTMRISI----TEIRQHPWFNN 272
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 136 bits (342), Expect = 1e-31
Identities = 101/298 (33%), Positives = 151/298 (49%), Gaps = 29/298 (9%)
Query: 295 SRALGEHVTGDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRK-KDTMRIYAM 353
S ++ +VTGD K +G D +LLG G F +VYQ ++ A+
Sbjct: 8 SESIIVNVTGD--------DNKSALFGKYDLG--KLLGSGAFAKVYQAEDLQNGGESVAI 57
Query: 354 KVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGEL 413
KV+ KK + K AH E +++ R P IV L T T +Y V + GGEL
Sbjct: 58 KVVQKKRL-KDGLTAHVKREISVMRRLRH---PHIVLLSEVLATKTKIYFVMELAKGGEL 113
Query: 414 FWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS 473
F + RFTE ++ Y +L+ A+ Y H + +RDLKPEN+LLD N ++ + DFGLS
Sbjct: 114 FSRVTSN-RFTESLSRKYFRQLISAVRYCHARGVFHRDLKPENLLLDENRDLKVSDFGLS 172
Query: 474 KADLKDR------TNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFA 527
+K++ +T CGT Y+APELL+ + D WS GV++F + G+ PF
Sbjct: 173 A--MKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDGSKADIWSCGVVLFLLNAGYLPFRD 230
Query: 528 SDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFN 585
+ +Y+KI + K P D S + R ++ LL NP+ R+ E+ P+FN
Sbjct: 231 PNIMGLYRKIHKAQYKLP-DWTSSDLRKLLRRLLEPNPELRITV----EEILKDPWFN 283
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 135 bits (341), Expect = 2e-31
Identities = 92/268 (34%), Positives = 144/268 (53%), Gaps = 22/268 (8%)
Query: 312 YTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIV-KKNEIAHT 370
Y + KK +G + LG GTFG V Q + +T A+K+L KK + K ++
Sbjct: 31 YVNKKKYVFG-------KTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEAL 83
Query: 371 IGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKF 430
E +IL R P IV K F++ Y++T GGELF + K+G+FTE+ A
Sbjct: 84 YDELDILQRL---HHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVR 140
Query: 431 YIAELVLALEYLHDNDIVYRDLKPENIL-LDANGN--IALCDFGLSKADLKDRTNTF--C 485
+ E++ A++Y+H +IV+RDLKPEN+L +D + + + DFG++K D +
Sbjct: 141 ILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPA 200
Query: 486 GTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VK 543
G+ Y+APE+L + G+ K D WS+GV+ + + CG+S F A Q + G+ VK
Sbjct: 201 GSLGYVAPEVLTQD-GHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVK 259
Query: 544 FPR---DVLSPEGRSFVKGLLNRNPKHR 568
F R D +S + + F+ LN +P R
Sbjct: 260 FHRPYWDSVSNKAKQFILKALNLDPSKR 287
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 135 bits (341), Expect = 2e-31
Identities = 92/318 (28%), Positives = 149/318 (45%), Gaps = 50/318 (15%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
DF L+ +G+G + QV++ R+ T ++A+KVL K + + ++ I E+NIL + +
Sbjct: 68 DFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQE 127
Query: 384 SS--PFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
PF+ L F +Y V + G+L L G F +KF+ +E++ L++
Sbjct: 128 CGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQF 187
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFG---------LSKADLKD------------- 479
LHDN IV+RD+KP+N+L+ +G+I + DFG LS+ D
Sbjct: 188 LHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSGS 247
Query: 480 ------------------RTNTFCGTTEYLAPELLMD-ETGYTKMVDFWSLGVLIFEMCC 520
R TF GT Y++PE+L D + G D W LG ++F+
Sbjct: 248 PPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVG--PQTDIWGLGCILFQCLA 305
Query: 521 GWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRA 580
G PF A + + ++I FP + E + +L R+P R+ +EL A
Sbjct: 306 GQPPFRAVNQYHLLKRIQELDFSFP-EGFPEEASEIIAKILVRDPSTRI----TSQELMA 360
Query: 581 HPFFNDIDWEAVRQKKIP 598
H FF ++DW + K P
Sbjct: 361 HKFFENVDWVNIANIKPP 378
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 135 bits (339), Expect = 3e-31
Identities = 80/246 (32%), Positives = 129/246 (51%), Gaps = 5/246 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
+F + +GKG FG V + T A+K+L++ + + T RN +
Sbjct: 23 NFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKT---RNEIDNLQKL 79
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+ P I L TP+D++LV + +SGGELF ++ ++G ++ Y +++ + Y H
Sbjct: 80 THPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCH 139
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLK-DRTNTFCGTTEYLAPELLMDETGY 502
++ IV+RDLKPEN+LLDAN NI + DFGLS D +T CG+ Y APEL+ ++
Sbjct: 140 NHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNKLYV 199
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN 562
VD WS GV+++ M CG PF + ++ KI G+ P + + + +L
Sbjct: 200 GPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYS-MEKQAADLISTMLQ 258
Query: 563 RNPKHR 568
+P R
Sbjct: 259 VDPVKR 264
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 134 bits (338), Expect = 4e-31
Identities = 81/245 (33%), Positives = 134/245 (54%), Gaps = 6/245 (2%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+++L+ +GKG F +V + T A+K++ K + + + E I+ +
Sbjct: 122 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTAL-NPSSLQKLFREVKIMKQL---D 177
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L +T LYLV ++ SGGE+F +L GR E A+ ++V A++YLH
Sbjct: 178 HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHS 237
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKA-DLKDRTNTFCGTTEYLAPELLMDETGYT 503
+I++RDLK EN+LLD + NI + DFG S L ++ +TFCG+ Y APEL +
Sbjct: 238 KNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDG 297
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
VD WSLGV+++ + G PF + +++ +++ GK + P +S + + +K L
Sbjct: 298 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP-FYMSTDCENLLKKFLVI 356
Query: 564 NPKHR 568
NP+ R
Sbjct: 357 NPQRR 361
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 134 bits (338), Expect = 4e-31
Identities = 81/245 (33%), Positives = 134/245 (54%), Gaps = 6/245 (2%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+++L+ +GKG F +V + T A+K++ K + + + E I+ +
Sbjct: 170 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTAL-NPSSLQKLFREVKIMKQL---D 225
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L +T LYLV ++ SGGE+F +L GR E A+ ++V A++YLH
Sbjct: 226 HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHS 285
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKA-DLKDRTNTFCGTTEYLAPELLMDETGYT 503
+I++RDLK EN+LLD + NI + DFG S L ++ +TFCG+ Y APEL +
Sbjct: 286 KNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDG 345
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
VD WSLGV+++ + G PF + +++ +++ GK + P +S + + +K L
Sbjct: 346 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP-FYMSTDCENLLKKFLVI 404
Query: 564 NPKHR 568
NP+ R
Sbjct: 405 NPQRR 409
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 134 bits (338), Expect = 4e-31
Identities = 88/249 (35%), Positives = 140/249 (55%), Gaps = 9/249 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+EV RLLG+GTF +VY R T A+K++ K +++ ++ I +R I V +K
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVG-LSQQI-KREISVMRIAKH 69
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P +V L T + +Y V ++ GGELF + K G+ ED A Y +L+ A+++ H
Sbjct: 70 -PNVVELYEVMATKSRIYFVIEYCKGGELFNKVAK-GKLKEDVAWKYFYQLISAVDFCHS 127
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDR---TNTFCGTTEYLAPELLMDET 500
+ +RD+KPEN+LLD N N+ + DFGLS AD K + +T CGT Y+APE++ +
Sbjct: 128 RGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKG 187
Query: 501 GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGL 560
D WS GV++F + G+ PF ++ +MY+KI K P +PE + + +
Sbjct: 188 YEGTKADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKIGKADFKCP-SWFAPEVKRLLCKM 246
Query: 561 LNRNPKHRL 569
L+ N + R+
Sbjct: 247 LDPNHETRI 255
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 134 bits (338), Expect = 4e-31
Identities = 80/250 (32%), Positives = 135/250 (54%), Gaps = 8/250 (3%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++E+ R LG+G+F +V + T A+K+L ++ + + + +R I K
Sbjct: 18 NYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQL--KREISTMKLIK 75
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
P +V + + T +Y+V + ++GGELF + ++GR ED A+ Y +L+ A++Y H
Sbjct: 76 H-PNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVDYCH 134
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR----TNTFCGTTEYLAPELLMDE 499
+ +RDLKPEN++LDANG + + DFGLS + R +T CGT Y+APE+L D+
Sbjct: 135 SRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEVLSDK 194
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKG 559
D WS GV++F + G+ PF + +Y++I + P S + +K
Sbjct: 195 GYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCP-PWFSQGAKRVIKR 253
Query: 560 LLNRNPKHRL 569
+L NP R+
Sbjct: 254 ILEPNPITRI 263
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 134 bits (337), Expect = 5e-31
Identities = 84/259 (32%), Positives = 142/259 (54%), Gaps = 12/259 (4%)
Query: 331 LGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVG 390
+G+G F + ++V K + IYA KV++K+ + GE + S S P IVG
Sbjct: 47 IGEGGFARCFRV-KDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKV---HQSMSHPNIVG 102
Query: 391 LKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYR 450
F+ T++YL+ + L L+K + TE ++ + +++ AL+Y+H +++R
Sbjct: 103 FIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHR 162
Query: 451 DLKPENILLDANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELLMD-ETGYTKMVD 507
DLK NI+LD + N+ + DFGL+ D ++R T CGT Y+APE+L + + G++ VD
Sbjct: 163 DLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVD 222
Query: 508 FWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV-LSPEGRSFVKGLLNRNPK 566
WS GV+++ + G PF + + +Y+KI FP +V +S E + + LL +P
Sbjct: 223 LWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDPS 282
Query: 567 HRLGAIDDGRELRAHPFFN 585
R +IDD + H FF+
Sbjct: 283 IR-PSIDD---IVDHEFFH 297
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 134 bits (337), Expect = 5e-31
Identities = 84/263 (31%), Positives = 143/263 (53%), Gaps = 11/263 (4%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++++ + LG G+FG+V T A+K+L+++ I K E+ + ++R
Sbjct: 19 NYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKI-KNMEMEEKVRREIKILRLFMH 77
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
P I+ +T +D+Y+V +++ GELF ++ ++GR ED A+ + +++ +EY H
Sbjct: 78 --PHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 135
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLMDETG 501
N +V+RDLKPEN+LLD+ NI + DFGLS ++D T CG+ Y APE++ +
Sbjct: 136 RNMVVHRDLKPENLLLDSRCNIKIADFGLSNV-MRDGHFLKTSCGSPNYAAPEVISGKLY 194
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
VD WS GV+++ + CG PF + +++KI G P LS E R + +L
Sbjct: 195 AGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSH-LSSEARDLIPRML 253
Query: 562 NRNPKHRLGAIDDGRELRAHPFF 584
+P R+ E+R H +F
Sbjct: 254 IVDPVKRITI----PEIRQHRWF 272
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 134 bits (337), Expect = 5e-31
Identities = 81/248 (32%), Positives = 131/248 (52%), Gaps = 6/248 (2%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+E+ R LG G+F +V+ R ++ + A+K++ KK ++ I E + + R +
Sbjct: 25 YELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEPRIIREIDAMRRL--RH 82
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ + T + +YLV + SGGELF + + GR E A+ Y +L AL + H
Sbjct: 83 HPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARRYFQQLASALRFSHQ 142
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKAD---LKDRTNTFCGTTEYLAPELLMDETG 501
+ + +RD+KP+N+LLD GN+ + DFGLS +T CGT Y APE++
Sbjct: 143 DGVAHRDVKPQNLLLDEQGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEVISRRGY 202
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLL 561
D WS GV++F + G PF S+ MY+KI +FP +S + +S + +L
Sbjct: 203 DGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHRRDYRFP-SWISKQAKSIIYQML 261
Query: 562 NRNPKHRL 569
+ NP R+
Sbjct: 262 DPNPVTRM 269
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 134 bits (336), Expect = 7e-31
Identities = 100/323 (30%), Positives = 155/323 (47%), Gaps = 21/323 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKK--VIVKKNEIAHTIGERNILVRTA 381
++ + + LG G G+V ++ T + A+K++SK+ I E + +
Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILK 278
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
+ P I+ +K +F D Y+V + M GGELF + R E K Y +++LA++Y
Sbjct: 279 KLNHPCIIKIK-NFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 442 LHDNDIVYRDLKPENILLDANGN---IALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLM 497
LH+N I++RDLKPEN+LL + I + DFG SK T CGT YLAPE+L+
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 498 D--ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQ-KMYQKIAFGKVKFPRDV---LSP 551
GY + VD WSLGV++F G+ PF Q + +I GK F +V +S
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 552 EGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFK----PHLIS 607
+ VK LL +PK R E HP+ D D + Q + + P +++
Sbjct: 458 KALDLVKKLLVVDPKARFTT----EEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLA 513
Query: 608 ETDTSNFDPEFTQTSTSFMNKQP 630
+ TS P + + K+P
Sbjct: 514 QPSTSRKRPREGEAEGAETTKRP 536
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 134 bits (336), Expect = 7e-31
Identities = 87/245 (35%), Positives = 130/245 (52%), Gaps = 6/245 (2%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+++++ LGKG F +V T R A+K++ K + N IA R + + +
Sbjct: 63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTAL---NTIARQKLYREVNIMK-KLN 118
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P IV L ++ LYLV +++SGGELF +L K GR E A+ +LV A+EY H
Sbjct: 119 HPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHS 178
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSKA-DLKDRTNTFCGTTEYLAPELLMDETGYT 503
IV+RDLK EN+LLD + + DFG S + K TFCG+ Y APEL +
Sbjct: 179 KSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSG 238
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
VD WSLGV+++ + G PF ++ +++ ++ GK + P V S E S ++ L
Sbjct: 239 PEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYV-SIECESLIRKFLVL 297
Query: 564 NPKHR 568
NP R
Sbjct: 298 NPTQR 302
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 133 bits (335), Expect = 9e-31
Identities = 110/389 (28%), Positives = 178/389 (45%), Gaps = 33/389 (8%)
Query: 331 LGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVG 390
LG GTFG+V + T A+K+L+++ I K ++ I R + P I+
Sbjct: 34 LGTGTFGKVKIGEHQITRVKVAVKILNRQKI-KSLDVVGKI--RREIQNLKLFRHPHIIK 90
Query: 391 LKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYR 450
L TP+D++++ +++SGGELF ++ K G+ E +A+ + +++ ++Y H + IV+R
Sbjct: 91 LYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHR 150
Query: 451 DLKPENILLDANGNIALCDFGLSKADLK-DRTNTFCGTTEYLAPELLMDETGYTKMVDFW 509
DLKPEN+LLD N ++ + DFGLS L + T CG+ Y APE++ + VD W
Sbjct: 151 DLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIW 210
Query: 510 SLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKHRL 569
S GV+++ + CG PF +++KI G P + L+ + + V +L +P R
Sbjct: 211 SCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIP-EYLNKQVVNLVCQMLQVDPLKRA 269
Query: 570 GAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKPHLISETDTSNFDP-EFTQTSTSFMNK 628
E++ H +F QK +P P I E D++ D + T F K
Sbjct: 270 NI----EEIKKHEWF---------QKDLPAYLFPSSI-EQDSNVIDTYAVAEVCTKFGVK 315
Query: 629 QPIAATPL---SPAMQAKFVGFTFVDESAIDEHYNNAYNNRKFLQNSYFMEPGSFIPGNP 685
+ L P Q +D + N N N++ F+ G+P
Sbjct: 316 ETEVHNSLLSGDPHDQLAIAYHLIIDNKRFADDAANQINE----INNF------FVAGSP 365
Query: 686 NLPPXXXXXXXXXXXXXRLAAVKGSGGIS 714
PP LA V GG S
Sbjct: 366 PPPPPPPVPQSSMDHQAPLATVTVGGGTS 394
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 132 bits (333), Expect = 1e-30
Identities = 87/293 (29%), Positives = 151/293 (50%), Gaps = 18/293 (6%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++++++ LG+G+FG+V T + A+K+++KKV+ K + ER I +
Sbjct: 54 NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRI--EREISYLRLLR 111
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
P I+ L ++ ++ +V ++ +G ELF ++ + + +E A+ + +++ A+EY H
Sbjct: 112 H-PHIIKLYDVIKSKDEIIMVIEY-AGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCH 169
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPELLMDETGY 502
+ IV+RDLKPEN+LLD + N+ + DFGLS T CG+ Y APE++ +
Sbjct: 170 RHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA 229
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN 562
VD WS GV+++ M C PF +++ I+ G P+ LSP +K +L
Sbjct: 230 GPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPK-FLSPGAAGLIKRMLI 288
Query: 563 RNPKHRLGAIDDGRELRAHPFFNDIDWEAV--RQKKIPPPFKPHLISETDTSN 613
NP +R+ H D DW V + +PP KPH E + ++
Sbjct: 289 VNPLNRIS---------IHEIMQD-DWFKVDLPEYLLPPDLKPHPEEENENND 331
>At1g16440 [R] KOG0610 Putative serine/threonine protein kinase
Length = 431
Score = 132 bits (333), Expect = 1e-30
Identities = 111/383 (28%), Positives = 172/383 (43%), Gaps = 82/383 (21%)
Query: 301 HVTGDILIHWEYTSTKKRQ---YGPQDFEVLRLLGKGTFGQVYQVRKK--DTMRIYAMKV 355
H GDI W+ ++ K + G DF VL+ LG G G VY V K + +AMKV
Sbjct: 20 HTGGDI--RWDAVNSLKSRGIKLGISDFRVLKRLGYGDIGSVYLVELKGANPTTYFAMKV 77
Query: 356 LSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFW 415
+ K +V +N++ ER IL + PF+ L F+T LV +F SGG L+
Sbjct: 78 MDKASLVSRNKLLRAQTEREIL---SQLDHPFLPTLYSHFETDKFYCLVMEFCSGGNLYS 134
Query: 416 HLQKEGR--FTEDRAKFYIAELVLALEY----------LHDNDIVYRD------------ 451
QK+ FTED A+F+ +E++LALEY L +++ RD
Sbjct: 135 LRQKQPNKCFTEDAARFFASEVLLALEYLHMLGIVYRDLKPENVLVRDDGHIMLSDFDLS 194
Query: 452 ----LKPENI----------LLDANGNIALC----------------------DFGLSKA 475
+ P + ++D N + C DF S
Sbjct: 195 LRCSVNPTLVKSFNGGGTTGIIDDNAAVQGCYQPSAFFPRMLQSSKKNRKSKSDFDGSLP 254
Query: 476 DLK-DRTN----TFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDN 530
+L + TN +F GT EYLAPE++ +E G+ VD+W+ G+ I+E+ G +PF N
Sbjct: 255 ELMAEPTNVKSMSFVGTHEYLAPEIIKNE-GHGSAVDWWTFGIFIYELLHGATPFKGQGN 313
Query: 531 QKMYQKIAFGKVKFPR-DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDW 589
+ + ++FP +S + +KGLL + P++R+ E++ HPFF ++W
Sbjct: 314 KATLYNVIGQPLRFPEYSQVSSTAKDLIKGLLVKEPQNRIAYKRGATEIKQHPFFEGVNW 373
Query: 590 EAVRQKKIPPPFKPHLISETDTS 612
+R + PHL D S
Sbjct: 374 ALIRGET-----PPHLPEPVDFS 391
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 132 bits (333), Expect = 1e-30
Identities = 88/283 (31%), Positives = 141/283 (49%), Gaps = 14/283 (4%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+++ R +GKG F V R + T A+K++ K + + N + E I+ R
Sbjct: 141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTN-LQKVYREVEIMKRL---K 196
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ L +T +Y+V+++ S GE+F ++ K GR +E A+F +++ A+EY H
Sbjct: 197 HPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHK 256
Query: 445 NDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLMDETGYT 503
IV+RDLK EN+LLD N NI + DFG S + T+CG+ Y APE+ +
Sbjct: 257 KGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTG 316
Query: 504 KMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNR 563
+D WSLGV+++ + CG PF S Q + ++ G+ + P +S E ++ +L
Sbjct: 317 PEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIP-FFMSSECEHLIRRMLVL 375
Query: 564 NPKHRLGAIDDGR-------ELRAHPFFNDIDWEAVRQKKIPP 599
P R ID + EL H + A RQ + P
Sbjct: 376 EPTRRY-TIDQIKRHRWMCPELLEHVLIAKYNLGAERQTSVEP 417
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 132 bits (332), Expect = 2e-30
Identities = 102/292 (34%), Positives = 150/292 (50%), Gaps = 33/292 (11%)
Query: 323 QDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVL--------SKKVIVKKNEIAHTIGER 374
+++E +LG+G V + K T + YA+KV+ S + + + E T+ E
Sbjct: 18 ENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREA--TLKEV 75
Query: 375 NILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAE 434
+IL + + P I+ LK +++T T +LV D M GELF +L ++ +E + +
Sbjct: 76 DILRKVSGH--PNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 133
Query: 435 LVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRTNTFCGTTEYLAP 493
L+ + LH +IV+RDLKPENILLD N NI L DFG S + + +R CGT YLAP
Sbjct: 134 LLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAP 193
Query: 494 ELL-----MDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDV 548
E++ D GY K VD WS GV+++ + G PF+ M + I G +F
Sbjct: 194 EIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFG--- 250
Query: 549 LSPEGRSF---VKGLLNR----NPKHRLGAIDDGRELRAHPFFNDIDWEAVR 593
SPE + VK L++R P++R A E AHPFF E VR
Sbjct: 251 -SPEWDDYSDTVKDLVSRFLVVQPQNRYTA----EEALAHPFFQQYLVEEVR 297
>At5g63650 [T] KOG0583 Serine/threonine protein kinase
Length = 360
Score = 132 bits (332), Expect = 2e-30
Identities = 88/268 (32%), Positives = 136/268 (49%), Gaps = 19/268 (7%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+EV++ LG G FG +R K+T + AMK + + + +N I R++
Sbjct: 4 YEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSL-------R 56
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
P I+ K TPT L +V ++ SGGELF + GRF+E A+++ +L+ ++Y H
Sbjct: 57 HPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHS 116
Query: 445 NDIVYRDLKPENILLDANGN--IALCDFGLSKAD-LKDRTNTFCGTTEYLAPELLMDETG 501
I +RDLK EN LLD + + +CDFG SK+ L R + GT Y+APE+L
Sbjct: 117 LQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREY 176
Query: 502 YTKMVDFWSLGVLIFEMCCGWSPFFASDN----QKMYQKIAFGKVKFPRDV-LSPEGRSF 556
K D WS GV ++ M G PF D+ +K Q+I + K P V +S E R
Sbjct: 177 DGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHL 236
Query: 557 VKGLLNRNPKHRLGAIDDGRELRAHPFF 584
+ + N R+ +E++ HP++
Sbjct: 237 LSRIFVTNSAKRITL----KEIKKHPWY 260
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 132 bits (332), Expect = 2e-30
Identities = 86/269 (31%), Positives = 138/269 (50%), Gaps = 22/269 (8%)
Query: 321 GPQDFEVLRLLGKGTFGQVYQ-----VRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERN 375
GP E + LGKG G V + KK ++I + LS+ V++K ER
Sbjct: 16 GPYRLE--KTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKV--------ERE 65
Query: 376 ILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAEL 435
I + P ++GL ++ LYL+ + +SGGELF +L K+GR T A+ + ++
Sbjct: 66 IAIMKLI-DHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQI 124
Query: 436 VLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGL-SKADLKDRTNTFCGTTEYLAPE 494
+ AL++ H + I +RDLKPEN+LLD NI + DFG+ S T CG+ Y PE
Sbjct: 125 ISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPE 184
Query: 495 LLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGR 554
++ E + D WS GV+++ + G PF + +++ +K+ G P V P+ +
Sbjct: 185 VIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFV-PPDCQ 243
Query: 555 SFVKGLLNRNPKHRLGAIDDGRELRAHPF 583
S ++G++ NP RL E+ HP+
Sbjct: 244 SLLRGMIEVNPDRRLTL----AEINRHPW 268
>7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 483
Score = 132 bits (331), Expect = 2e-30
Identities = 80/202 (39%), Positives = 117/202 (57%), Gaps = 8/202 (3%)
Query: 325 FEVLRLLGKGTFGQVYQVRKK-DTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
+ + L+ KG FG V++V K D + YA+KVL K +++ N + E +I +
Sbjct: 159 YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADI--QKVCG 216
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
PFIV +Q +L+++++++ GELF K F+ D + YI E+ LAL++LH
Sbjct: 217 HHPFIVKQIDLWQNRHNLHILSEYVPNGELF---SKITHFSIDLVRLYIGEIALALDFLH 273
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLSK-ADLKDRTNTFCGTTEYLAPELLMDETGY 502
+ I+YRD KPENILL +I L DFGLSK L T T CGT +Y+APE+L E Y
Sbjct: 274 NAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKYMAPEILCGEP-Y 332
Query: 503 TKMVDFWSLGVLIFEMCCGWSP 524
VD+W+LGV+ +M SP
Sbjct: 333 GHAVDWWALGVIACQMLTQKSP 354
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 131 bits (330), Expect = 3e-30
Identities = 84/256 (32%), Positives = 137/256 (52%), Gaps = 16/256 (6%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+++ L+G G+F +V +V +K T + +A+KV+ + ++ + E ++L R + +
Sbjct: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETR---EREGREACVSELSVLRRVSHR- 118
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
+IV L F+T +Y+V + +GGELF L +G FTE A + + + YLH
Sbjct: 119 --YIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHA 176
Query: 445 NDIVYRDLKPENILLDANG---NIALCDFGLSKADLKD---RTNTFCGTTEYLAPELLMD 498
I +R+LKPEN+L G I + DFGL+ + K T CGT EY+APE+L+
Sbjct: 177 LQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLR 236
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKF---PRDVLSPEGRS 555
+ YT VD W+LGV+ + + G+ PF ++Y+KI GK + P +S +
Sbjct: 237 KP-YTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
Query: 556 FVKGLLNRNPKHRLGA 571
F+ LL HR+ A
Sbjct: 296 FIDKLLILEAGHRMSA 311
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 131 bits (330), Expect = 3e-30
Identities = 90/275 (32%), Positives = 139/275 (49%), Gaps = 12/275 (4%)
Query: 295 SRALGEHVTGDILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMK 354
SR+LG I S + Q ++ +LR +GKG +V R T R A+K
Sbjct: 35 SRSLGARCRNSI------ASCPEEQPHVGNYRLLRTIGKGNSAKVKLARHILTGREVAIK 88
Query: 355 VLSKKVIVKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELF 414
++ K + + + E I+ + P IV L +T LYLV ++ S GE+F
Sbjct: 89 IIDKTQL-NPSSLQKLFREVRIM---KGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVF 144
Query: 415 WHLQKEGRFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS- 473
+L GR E A+ ++V A+ Y H +IV+RDLK EN+LLDA NI + DFG S
Sbjct: 145 DYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN 204
Query: 474 KADLKDRTNTFCGTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKM 533
+ L + +TFCG+ Y APEL + VD WSLGV+++ + G PF + +++
Sbjct: 205 EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKEL 264
Query: 534 YQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNPKHR 568
+++ GK + P +S + S ++ L NP R
Sbjct: 265 RERVLRGKYRVP-FYMSTDCESILRRFLVLNPAKR 298
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 131 bits (330), Expect = 3e-30
Identities = 87/254 (34%), Positives = 140/254 (54%), Gaps = 18/254 (7%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKS 384
+EVL ++GKG+F QV +V+ + T + +A+KV++ NE+ NIL R S
Sbjct: 71 YEVLAVVGKGSFSQVLRVQHRVTRKYFAVKVVNGDCGAVNNEL-------NILSRL---S 120
Query: 385 SPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHD 444
PF++ L+ F++ + L++V SGGE++ + +GR++E+ A+ + L+ L YLH
Sbjct: 121 HPFVIRLEEVFKSSSKLFIVMQMASGGEMYDRVVAKGRYSEEEARNALKMLLTGLTYLHS 180
Query: 445 NDIVYRDLKPENILL---DANGNIALCDFGLS-KADLKDRTNT-FCGTTEYLAPELLMDE 499
+ +RDLKPEN+L + + DFGL+ +A + T T CGT EY+APELL+
Sbjct: 181 IRVTHRDLKPENLLYADSRPEARLLITDFGLAYQATKPNETMTETCGTPEYIAPELLL-R 239
Query: 500 TGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK-VKFPRDVLSPE-GRSFV 557
YT+ VD W++GV+ + + G PF ++Y I V +P+ E + FV
Sbjct: 240 VPYTQKVDMWAVGVIAYILMSGIMPFDDDCRSRLYTHIITANYVYYPQFWSGSELAKQFV 299
Query: 558 KGLLNRNPKHRLGA 571
LL N RL +
Sbjct: 300 DSLLETNSVERLSS 313
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 131 bits (329), Expect = 4e-30
Identities = 87/251 (34%), Positives = 133/251 (52%), Gaps = 15/251 (5%)
Query: 329 RLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKN-EIAHTIGERNILVRTASKSSPF 387
R LG G+FG V Q RK T A+K+L KK + N ++ E +IL + S P
Sbjct: 51 RTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKL---SHPN 107
Query: 388 IVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDNDI 447
IV K F++ Y+VT +GGELF + G+FTE A I +++ A+EY+H ++
Sbjct: 108 IVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNV 167
Query: 448 VYRDLKPENILL---DANGNIALCDFGLSK--ADLKDRTNTFCGTTEYLAPELLMDETGY 502
V+RDLKPEN+L N + + DFG++K +D G+ Y+APE+L + G+
Sbjct: 168 VHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQD-GH 226
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGK--VKFPR---DVLSPEGRSFV 557
K D WS+GV+ + + CG+SPF A + ++ + V F D +S + + F+
Sbjct: 227 GKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFI 286
Query: 558 KGLLNRNPKHR 568
L NP R
Sbjct: 287 LKALRLNPADR 297
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 131 bits (329), Expect = 4e-30
Identities = 87/250 (34%), Positives = 128/250 (50%), Gaps = 16/250 (6%)
Query: 325 FEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK- 383
++V R +GKG F T+RI K+ KV +K +++ E I + K
Sbjct: 16 YDVGRAIGKGNFA---------TVRIARHKIAKTKVAIKSIDVSALDRENLIKLEREVKI 66
Query: 384 ----SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLAL 439
P IV + LY+V+++ S GEL+ L ++GR E+ A+ + +E A+
Sbjct: 67 VKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKWFSETASAV 126
Query: 440 EYLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR-TNTFCGTTEYLAPELLMD 498
YLH IV+RDLK ENILL N NI + DFG S D+ NT+CG+ Y APELL+
Sbjct: 127 AYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQTGDQLLNTWCGSPPYAAPELLLG 186
Query: 499 ETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVK 558
+ D WS+GVL++ + G PF + K+ + + G VK P V S E F++
Sbjct: 187 NSYDGMKADIWSMGVLLYILVAGGFPFPSDSVNKLKRSVLSGLVKIPYWV-SVECADFIR 245
Query: 559 GLLNRNPKHR 568
+L NP R
Sbjct: 246 KMLVLNPGKR 255
>7300437 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 866
Score = 131 bits (329), Expect = 4e-30
Identities = 66/157 (42%), Positives = 107/157 (68%), Gaps = 4/157 (2%)
Query: 323 QDFEVLRLLGKGTFGQVYQ-VRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTA 381
+DF +++ + +G FG+V+ + D+ R++A+KV+ K ++ KN ++ I ERN L A
Sbjct: 55 KDFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQVITERNAL---A 111
Query: 382 SKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEY 441
S F V L +S Q+ + +YLV ++M GG+L L G F E A+FY+AE+V+AL+Y
Sbjct: 112 LSRSQFCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMALQY 171
Query: 442 LHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK 478
LH + IV+RD+KP+N+LL ++G++ L DFGLSK D++
Sbjct: 172 LHQHGIVHRDIKPDNMLLSSSGHVKLTDFGLSKIDMR 208
Score = 73.2 bits (178), Expect = 1e-12
Identities = 48/132 (36%), Positives = 69/132 (51%), Gaps = 9/132 (6%)
Query: 486 GTTEYLAPELLMDETGYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFP 545
GT +YLAPELL+ + G+ VD+W+LGV +E G PF QK++ I +++P
Sbjct: 725 GTPDYLAPELLLKQ-GHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVFDNILNKNIEWP 783
Query: 546 R--DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFNDIDWEAVRQKKIPPPFKP 603
+ LS E V+ LL +P R A +E++ F IDWE + + PPF P
Sbjct: 784 EGDEALSVESMEAVELLLTMDPNERPAA----KEVQQMRHFACIDWENIGNTE--PPFVP 837
Query: 604 HLISETDTSNFD 615
+ TDT FD
Sbjct: 838 TPDNPTDTGYFD 849
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 130 bits (328), Expect = 6e-30
Identities = 82/246 (33%), Positives = 133/246 (53%), Gaps = 6/246 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++ +L+ +GKG F +V R T + A+K++ K + + + E I+
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIM---KVL 74
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+ P IV L +T LYLV ++ SGGE+F +L GR E A+ ++V A++Y H
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRTNTFCGTTEYLAPELLMDETGY 502
IV+RDLK EN+LLDA+ NI + DFG S + ++ +TFCG+ Y APEL +
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN 562
VD WSLGV+++ + G PF + +++ +++ GK + P +S + + +K L
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP-FYMSTDCENLLKKFLI 253
Query: 563 RNPKHR 568
NP R
Sbjct: 254 LNPSKR 259
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 130 bits (328), Expect = 6e-30
Identities = 82/246 (33%), Positives = 133/246 (53%), Gaps = 6/246 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++ +L+ +GKG F +V R T + A+K++ K + + + E I+
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIM---KVL 74
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+ P IV L +T LYLV ++ SGGE+F +L GR E A+ ++V A++Y H
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRTNTFCGTTEYLAPELLMDETGY 502
IV+RDLK EN+LLDA+ NI + DFG S + ++ +TFCG+ Y APEL +
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN 562
VD WSLGV+++ + G PF + +++ +++ GK + P +S + + +K L
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP-FYMSTDCENLLKKFLI 253
Query: 563 RNPKHR 568
NP R
Sbjct: 254 LNPSKR 259
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 130 bits (328), Expect = 6e-30
Identities = 82/246 (33%), Positives = 133/246 (53%), Gaps = 6/246 (2%)
Query: 324 DFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASK 383
++ +L+ +GKG F +V R T + A+K++ K + + + E I+
Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIM---KVL 107
Query: 384 SSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLH 443
+ P IV L +T LYLV ++ SGGE+F +L GR E A+ ++V A++Y H
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167
Query: 444 DNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDRTNTFCGTTEYLAPELLMDETGY 502
IV+RDLK EN+LLDA+ NI + DFG S + ++ +TFCG+ Y APEL +
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYD 227
Query: 503 TKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLN 562
VD WSLGV+++ + G PF + +++ +++ GK + P +S + + +K L
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP-FYMSTDCENLLKKFLI 286
Query: 563 RNPKHR 568
NP R
Sbjct: 287 LNPSKR 292
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 130 bits (328), Expect = 6e-30
Identities = 83/245 (33%), Positives = 125/245 (50%), Gaps = 14/245 (5%)
Query: 331 LGKGTFGQVYQVRKKDTMRIYAMKVLSKKVIVKKNEIAHTIGERNILVRTASKSS----P 386
+G G F QV T A+K+L K + +K + +L R S P
Sbjct: 80 IGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQ--------RLLSREISSMEKLHHP 131
Query: 387 FIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEGRFTEDRAKFYIAELVLALEYLHDND 446
I+ L +T + L+LV ++ GGELF + EG+ +E +K +++V A++++H+N
Sbjct: 132 NIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQ 191
Query: 447 IVYRDLKPENILLDANGNIALCDFGLSKADLK-DRTNTFCGTTEYLAPELLMDETGYTKM 505
I++RDLK EN+ +N + + DFG S K + NTFCG+ Y APEL DE
Sbjct: 192 IIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIY 251
Query: 506 VDFWSLGVLIFEMCCGWSPFFASDNQKMYQKIAFGKVKFPRDVLSPEGRSFVKGLLNRNP 565
VD W+LGVL++ M G PF A K+ + I G P V P R ++G+L + P
Sbjct: 252 VDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHR-LIRGVLQQIP 310
Query: 566 KHRLG 570
R G
Sbjct: 311 TERYG 315
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 130 bits (327), Expect = 7e-30
Identities = 94/292 (32%), Positives = 148/292 (50%), Gaps = 21/292 (7%)
Query: 305 DILIHWEYTSTKKRQYGPQDFEVLRLLGKGTFGQVYQVRKKDTMRIYAMKVL---SKKVI 361
D L W ++Y P+D ++G+G V + + T +A+K++ ++++
Sbjct: 9 DELPDWAAAKEFYQKYDPKD-----VIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLS 63
Query: 362 VKKNEIAHTIGERNILVRTASKSSPFIVGLKFSFQTPTDLYLVTDFMSGGELFWHLQKEG 421
++ E R + P I+ L S+++ + ++LV D M GELF +L ++
Sbjct: 64 PEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKV 123
Query: 422 RFTEDRAKFYIAELVLALEYLHDNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKDR 480
+E + + L+ A+ +LH N+IV+RDLKPENILLD N I L DFG S + ++
Sbjct: 124 ALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEK 183
Query: 481 TNTFCGTTEYLAPELL---MDET--GYTKMVDFWSLGVLIFEMCCGWSPFFASDNQKMYQ 535
CGT YLAPE+L MDET GY K VD W+ GV++F + G PF+ M +
Sbjct: 184 LRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLR 243
Query: 536 KIAFGKVKFPR---DVLSPEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFF 584
I G+ +F D S + + LL +P+ RL A + HPFF
Sbjct: 244 MIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTA----EQALQHPFF 291
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,672,496
Number of Sequences: 60738
Number of extensions: 1890194
Number of successful extensions: 10353
Number of sequences better than 1.0e-05: 1641
Number of HSP's better than 0.0 without gapping: 562
Number of HSP's successfully gapped in prelim test: 1079
Number of HSP's that attempted gapping in prelim test: 6125
Number of HSP's gapped (non-prelim): 1972
length of query: 734
length of database: 30,389,216
effective HSP length: 114
effective length of query: 620
effective length of database: 23,465,084
effective search space: 14548352080
effective search space used: 14548352080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)