ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1015 good O KOG2884 Posttranslational modification, protein turnover, chaperones 26S proteasome regulatory complex, subunit RPN10/PSMD4
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1015 358055 357315 -247
(247 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR200w [O] KOG2884 26S proteasome regulatory complex subunit RP... 297 8e-81
Hs5292161 [O] KOG2884 26S proteasome regulatory complex subunit ... 189 4e-48
SPAC637.10c [O] KOG2884 26S proteasome regulatory complex subuni... 182 4e-46
At4g38630 [O] KOG2884 26S proteasome regulatory complex subunit ... 169 3e-42
7296454 [O] KOG2884 26S proteasome regulatory complex subunit RP... 164 1e-40
CE26355 [O] KOG2884 26S proteasome regulatory complex subunit RP... 151 7e-37
>YHR200w [O] KOG2884 26S proteasome regulatory complex subunit RPN10/PSMD4
Length = 268
Score = 297 bits (761), Expect = 8e-81
Identities = 151/237 (63%), Positives = 185/237 (77%), Gaps = 7/237 (2%)
Query: 1 MVLEATVLVVDNSEYARNGDFPRTRFVAQVDAVEYIFQAKRNSNPENTIGLVSAAEANPK 60
MVLEATVLV+DNSEY+RNGDFPRTRF AQ+D+VE+IFQAKRNSNPENT+GL+S A ANP+
Sbjct: 1 MVLEATVLVIDNSEYSRNGDFPRTRFEAQIDSVEFIFQAKRNSNPENTVGLISGAGANPR 60
Query: 61 VLSTFTNEFGKILSGLHDINIGGSIHFATAIQIAALTLKHXXXXXXXXXXXXFVCSPITE 120
VLSTFT EFGKIL+GLHD I G +H ATA+QIA LTLKH FVCSPI++
Sbjct: 61 VLSTFTAEFGKILAGLHDTQIEGKLHMATALQIAQLTLKHRQNKVQHQRIVAFVCSPISD 120
Query: 121 DRQDLIKMAKKLKKNSIAVDVINFGETDTNADLLEEFVETVNSGQEDSKSTLLNIDAGPK 180
R +LI++AK LKKN++AVD+INFGE + N +LL+EF+ VN+ QE++ S LL + GP+
Sbjct: 121 SRDELIRLAKTLKKNNVAVDIINFGEIEQNTELLDEFIAAVNNPQEET-SHLLTVTPGPR 179
Query: 181 LLYEHVAASPIVL-EGPAAEAGFSMGGNDD-----FMDFGVDPSLDPELAMALRLSM 231
LLYE++A+SPI+L EG + F G D FMDFGVDPS+DPELAMALRLSM
Sbjct: 180 LLYENIASSPIILEEGSSGMGAFGGSGGDSDANGTFMDFGVDPSMDPELAMALRLSM 236
>Hs5292161 [O] KOG2884 26S proteasome regulatory complex subunit RPN10/PSMD4
Length = 377
Score = 189 bits (479), Expect = 4e-48
Identities = 109/232 (46%), Positives = 150/232 (63%), Gaps = 9/232 (3%)
Query: 1 MVLEATVLVVDNSEYARNGDFPRTRFVAQVDAVEYIFQAKRNSNPENTIGLVSAAEANPK 60
MVLE+T++ VDNSEY RNGDF TR AQ DAV + +K SNPEN +GL++ A + +
Sbjct: 1 MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLAN-DCE 59
Query: 61 VLSTFTNEFGKILSGLHDINIGGSIHFATAIQIAALTLKHXXXXXXXXXXXXFVCSPITE 120
VL+T T + G+ILS LH + G I F T I++A L LKH FV SP+ +
Sbjct: 60 VLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVED 119
Query: 121 DRQDLIKMAKKLKKNSIAVDVINFGETDTNADLLEEFVETVNSGQEDSKSTLLNIDAGPK 180
+ +DL+K+AK+LKK + VD+INFGE + N + L FV T+N G++ + S L+ + GP
Sbjct: 120 NEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLN-GKDGTGSHLVTVPPGPS 178
Query: 181 LLYEHVAASPIVLEGPAAEAGFSMG-GNDDFMDFGVDPSLDPELAMALRLSM 231
L + + +SPI+ A E G +G G DF +FGVDPS DPELA+ALR+SM
Sbjct: 179 LA-DALISSPIL----AGEGGAMLGLGASDF-EFGVDPSADPELALALRVSM 224
>SPAC637.10c [O] KOG2884 26S proteasome regulatory complex subunit RPN10/PSMD4
Length = 243
Score = 182 bits (462), Expect = 4e-46
Identities = 102/247 (41%), Positives = 145/247 (58%), Gaps = 13/247 (5%)
Query: 1 MVLEATVLVVDNSEYARNGDFPRTRFVAQVDAVEYIFQAKRNSNPENTIGLVSAAEANPK 60
MVLEAT++++DNSE+ NGD+ TRF AQ D V IF K N NPEN GL++ + +P+
Sbjct: 1 MVLEATMILIDNSEWMINGDYIPTRFEAQKDTVHMIFNQKINDNPENMCGLMTIGDNSPQ 60
Query: 61 VLSTFTNEFGKILSGLHDINIGGSIHFATAIQIAALTLKHXXXXXXXXXXXXFVCSPITE 120
VLST T ++GK LS +HD+ + G+ F IQIA L LKH FV SPI E
Sbjct: 61 VLSTLTRDYGKFLSAMHDLPVRGNAKFGDGIQIAQLALKHRENKIQRQRIVAFVGSPIVE 120
Query: 121 DRQDLIKMAKKLKKNSIAVDVINFGETDTNADLLEEFVETVNSGQEDSKSTLLNIDAGPK 180
D ++LI++AK++KKN++A+D+I+ GE N L+ F++ NS L++I P+
Sbjct: 121 DEKNLIRLAKRMKKNNVAIDIIHIGELQ-NESALQHFIDAANS---SDSCHLVSIPPSPQ 176
Query: 181 LLYEHVAASPIVLEGPAAEAGFSMGGNDDFMDFGVDPSLDPELAMALRLSMXXXXXXXXX 240
LL + V SPI G + + + ++GVDP+LD ELA+AL LSM
Sbjct: 177 LLSDLVNQSPI---------GQGVVASQNQFEYGVDPNLDVELALALELSMAEERARQEV 227
Query: 241 XXXNSTE 247
S+E
Sbjct: 228 AAQKSSE 234
>At4g38630 [O] KOG2884 26S proteasome regulatory complex subunit RPN10/PSMD4
Length = 386
Score = 169 bits (429), Expect = 3e-42
Identities = 98/240 (40%), Positives = 149/240 (61%), Gaps = 15/240 (6%)
Query: 1 MVLEATVLVVDNSEYARNGDFPRTRFVAQVDAVEYIFQAKRNSNPENTIGLVSAAEANPK 60
MVLEAT++ +DNSE+ RNGD+ +R AQ +AV + AK SNPENT+G+++ A +
Sbjct: 1 MVLEATMICIDNSEWMRNGDYSPSRLQAQTEAVNLLCGAKTQSNPENTVGILTMAGKGVR 60
Query: 61 VLSTFTNEFGKILSGLHDINIGGSIHFATAIQIAALTLKHXXXXXXXXXXXXFVCSPITE 120
VL+T T++ GKIL+ +H +++GG I+ AIQIA L LKH F SPI
Sbjct: 61 VLTTPTSDLGKILACMHGLDVGGEINLTAAIQIAQLALKHRQNKNQRQRIIVFAGSPIKY 120
Query: 121 DRQDLIKMAKKLKKNSIAVDVINFGETD--TNADLLEEFVETVNSGQEDSKSTLLNIDAG 178
+++ L + K+LKKNS+++D++NFGE D LE + VN+ + S ++++ +G
Sbjct: 121 EKKALEIVGKRLKKNSVSLDIVNFGEDDDEEKPQKLEALLTAVNN---NDGSHIVHVPSG 177
Query: 179 PKLLYEHVAASPIVL--EG-----PAAEAGFSMGGNDDFMDFGVDPSLDPELAMALRLSM 231
L + + ++P+ EG AA A + GG+ DFGVDP++DPELA+ALR+SM
Sbjct: 178 ANALSDVLLSTPVFTGDEGASGYVSAAAAAAAAGGD---FDFGVDPNIDPELALALRVSM 234
>7296454 [O] KOG2884 26S proteasome regulatory complex subunit RPN10/PSMD4
Length = 396
Score = 164 bits (414), Expect = 1e-40
Identities = 91/231 (39%), Positives = 142/231 (61%), Gaps = 6/231 (2%)
Query: 1 MVLEATVLVVDNSEYARNGDFPRTRFVAQVDAVEYIFQAKRNSNPENTIGLVSAAEANPK 60
MVLE+T++ DNS++ RNGD+ TR + Q D + + K SNPEN +GL++ + +
Sbjct: 1 MVLESTMICFDNSDFQRNGDYFPTRLIVQRDGINLVCLTKLRSNPENNVGLMTLSNT-VE 59
Query: 61 VLSTFTNEFGKILSGLHDINIGGSIHFATAIQIAALTLKHXXXXXXXXXXXXFVCSPITE 120
VL+T T++ G+I S +H + G I+ T I+IA L LKH FV SPI
Sbjct: 60 VLATLTSDAGRIFSKMHLVQPKGEINLLTGIRIAHLVLKHRQGKNHKMRIVVFVGSPINH 119
Query: 121 DRQDLIKMAKKLKKNSIAVDVINFGETDTNADLLEEFVETVNSGQEDSKSTLLNIDAGPK 180
+ DL+K AK+LKK + VD+++FG+ N ++L F+ +N G++ + S L+++ G
Sbjct: 120 EEGDLVKQAKRLKKEKVNVDIVSFGDHGNNNEILTAFINALN-GKDGTGSHLVSVPRG-S 177
Query: 181 LLYEHVAASPIVLEGPAAEAGFSMGGNDDFMDFGVDPSLDPELAMALRLSM 231
+L + + +SPI+ +G G +GGN +FGVDP+ DPELA+ALR+SM
Sbjct: 178 VLSDALLSSPII-QGEDGMGGAGLGGN--VFEFGVDPNEDPELALALRVSM 225
>CE26355 [O] KOG2884 26S proteasome regulatory complex subunit RPN10/PSMD4
Length = 346
Score = 151 bits (382), Expect = 7e-37
Identities = 93/233 (39%), Positives = 137/233 (57%), Gaps = 6/233 (2%)
Query: 1 MVLEATVLVVDNSEYARNGDFPRTRFVAQVDAVEYIFQAKRNSNPENTIGLVSAAEANPK 60
MV E+T++ VDNSEY RNGDF TR +Q DAV + Q K +NPEN +G++S A + +
Sbjct: 1 MVQESTMICVDNSEYMRNGDFQPTRLQSQQDAVNLVTQCKLRANPENAVGILSMAN-SVQ 59
Query: 61 VLSTFTNEFGKILSGLHDINIGGSIHFATAIQIAALTLKHXXXXXXXXXXXXFVCSPITE 120
VLS+ + E G+++ H I G +F I+IA L LKH F+ SP+ E
Sbjct: 60 VLSSLSTEQGRLMMKNHSIEPFGKCNFIAGIKIAHLALKHRQNRNHKMRVVLFIGSPLEE 119
Query: 121 -DRQDLIKMAKKLKKNSIAVDVINFGETDTNA-DLLEEFVETVNSGQEDSKSTLLNIDAG 178
+ +L+K+AKK+KK + DVI FGE +++ + FV+T+N G+E S S+L+ + G
Sbjct: 120 IEMNELVKIAKKMKKEKVLCDVIMFGENESDGHEKFSTFVDTLN-GKEGSGSSLIVVPQG 178
Query: 179 PKLLYEHVAASPIVLEGPAAEAGFSMGGNDDFMDFGVDPSLDPELAMALRLSM 231
L + +S V + +A F GGN FG+D DP+LA+ALR+SM
Sbjct: 179 SSLTDALLQSS--VCKNEDGQAAFGGGGNGMDNAFGMDVENDPDLALALRVSM 229
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,386,894
Number of Sequences: 60738
Number of extensions: 474642
Number of successful extensions: 1223
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1205
Number of HSP's gapped (non-prelim): 6
length of query: 247
length of database: 30,389,216
effective HSP length: 104
effective length of query: 143
effective length of database: 24,072,464
effective search space: 3442362352
effective search space used: 3442362352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)