ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1164 good F KOG2056 Nucleotide transport and metabolism Equilibrative nucleoside transporter protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1164 411097 412296 400
(400 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR125c [F] KOG2056 Equilibrative nucleoside transporter protein 348 1e-95
SPCC794.11c [F] KOG2056 Equilibrative nucleoside transporter pro... 227 3e-59
Hs7661968 [F] KOG2057 Predicted equilibrative nucleoside transpo... 155 1e-37
Hs7019369 [F] KOG2056 Equilibrative nucleoside transporter protein 146 6e-35
Hs8923678 [F] KOG2056 Equilibrative nucleoside transporter protein 144 2e-34
Hs7662468 [F] KOG2056 Equilibrative nucleoside transporter protein 144 2e-34
7300848_1 [F] KOG2057 Predicted equilibrative nucleoside transpo... 142 9e-34
At2g43160 [F] KOG2056 Equilibrative nucleoside transporter protein 131 2e-30
7295219 [F] KOG2056 Equilibrative nucleoside transporter protein 129 6e-30
CE26821 [F] KOG2056 Equilibrative nucleoside transporter protein 125 8e-29
CE03062 [F] KOG2057 Predicted equilibrative nucleoside transport... 125 8e-29
At5g11710 [F] KOG2056 Equilibrative nucleoside transporter protein 125 8e-29
CE26820 [F] KOG2056 Equilibrative nucleoside transporter protein 122 9e-28
At3g59290_1 [F] KOG2056 Equilibrative nucleoside transporter pro... 122 9e-28
SPCC162.07 [F] KOG2056 Equilibrative nucleoside transporter protein 117 2e-26
Hs17456254 [F] KOG2056 Equilibrative nucleoside transporter protein 114 2e-25
YDL161w [F] KOG2056 Equilibrative nucleoside transporter protein 96 7e-20
At3g46540 [F] KOG2056 Equilibrative nucleoside transporter protein 94 5e-19
YLR206w [F] KOG2056 Equilibrative nucleoside transporter protein 91 2e-18
YLL038c [F] KOG2056 Equilibrative nucleoside transporter protein 64 3e-10
YDR153c [F] KOG2056 Equilibrative nucleoside transporter protein 62 2e-09
>YJR125c [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 408
Score = 348 bits (892), Expect = 1e-95
Identities = 207/417 (49%), Positives = 248/417 (58%), Gaps = 26/417 (6%)
Query: 1 MSLEDTITKLSLYDAKKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTY 60
MSLEDT+ +SLYDAKKYFRKAQNVVFNYTEME KVREATNNEPWGASSTLM+ I+QGTY
Sbjct: 1 MSLEDTLANMSLYDAKKYFRKAQNVVFNYTEMEGKVREATNNEPWGASSTLMDQISQGTY 60
Query: 61 NYREREEILGMIFRRFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLE 120
N+REREEIL MIFRRFTEK SEWRQIYKALQLL+YL+KHGSERFIDD R ++NL+++LE
Sbjct: 61 NFREREEILSMIFRRFTEKAGSEWRQIYKALQLLDYLIKHGSERFIDDTRNSINLIRILE 120
Query: 121 SFHYIDSQGRDQGINVRNRASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXX 180
+FHYIDSQGRDQGINVR R L++LL D +IR ERKKARET KKYK
Sbjct: 121 TFHYIDSQGRDQGINVRTRVKALIELLSDDNKIRAERKKARETAKKYK-GVAGGSASADG 179
Query: 181 NINSRAGYTKSTSHGISVSADFDSDDDEGYQKPLPYGQDNGNGMRASTEEYQPKINEETS 240
++NS+AG+T + HGISVSADFDSD+++ N N RA++ Q K +E
Sbjct: 180 SLNSKAGFTSTKVHGISVSADFDSDNEDNEDGSFSQNGYNDNASRATSTPGQGK--QEPE 237
Query: 241 DLFDFQDTPGPVSQSRDTNGNGISSHXXXXXXXXXXXXXXXXXQSATPSASTKKSGGLDD 300
D DF S+S + I QSA P + S L +
Sbjct: 238 DFVDFFS-----SESSKPSKELIQEDEKKADEEEDDDDEFSEFQSAVPVTNPANSFNLLN 292
Query: 301 LIFSNNNSFATPSHTYVPSAT-----VTPAIAETSKNSDPFGSLFSSAK------NEPFX 349
T S + S+T +TPAIAE K DPF SLFS+AK + P
Sbjct: 293 TSPIEGMPATTSSMPFYNSSTTDQGKITPAIAE-PKKVDPFSSLFSTAKASAEAPSAPKA 351
Query: 350 XXXXXXXXXLNANTNNA----SKDTDLFGDLXXXXXXXXXXXTNN--KSEEIDLLSF 400
+N+ A D D FG++ NN S+EIDLLSF
Sbjct: 352 SQAKAAASNPVSNSTTALSTDQDDDDEFGEMHGGAVQQEQNTNNNHTSSKEIDLLSF 408
>SPCC794.11c [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 476
Score = 227 bits (578), Expect = 3e-59
Identities = 148/381 (38%), Positives = 193/381 (49%), Gaps = 44/381 (11%)
Query: 2 SLEDTITKLSLYDAKKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYN 61
S++ T+ ++LYD K RKAQNVV NYT MEA+VREATNNEPWGAS++LM IAQGT+N
Sbjct: 3 SIQSTMKNINLYDIKAAVRKAQNVVMNYTSMEARVREATNNEPWGASTSLMMEIAQGTHN 62
Query: 62 YREREEILGMIFRRFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLES 121
Y + EIL MI+RRFTEKTA EWRQIYKALQLLE+LVK+GSER +DD R + +KML +
Sbjct: 63 YSQLNEILPMIYRRFTEKTAEEWRQIYKALQLLEFLVKNGSERVVDDARAHQATIKMLRN 122
Query: 122 FHYIDSQGRDQGINVRNRASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXN 181
FHYID + +DQG+NVR RA +LV+LL E+IR+ERK+AR+ K+
Sbjct: 123 FHYIDHRQKDQGLNVRTRAKELVELLNDSERIRKERKRARQNRGKF------------IG 170
Query: 182 INSRAGYTKSTSHGISVSADFDSDDDEGYQKPLPYGQ-----DNGNGMRASTEEYQPKIN 236
+ S STS S S G + YG D GNG
Sbjct: 171 VGSDGDSRISTS---SKSRFPSFGSSRGSYRTRVYGDGGGFTDYGNGY------------ 215
Query: 237 EETSDLFDFQDTPGPVSQSRDTNGNGISSHXXXXXXXXXXXXXXXXXQSATPSASTKKSG 296
++S + D +D + + +G+G SS P ++S
Sbjct: 216 HDSSSMSDSRDASDNDVEEYNEDGDGGSSDAATANSTRGSRRTTTKQSDKAPEQPKQESA 275
Query: 297 GLDDLIFSNNNSFATPSHTYVPSATVTPAIAETSKNSDPFGSLFSSAKNEPFXXXXXXXX 356
+D L N S A P T A + D FG F S+ P
Sbjct: 276 MIDLLGLDNEPSPAQPQ---------TNTSAPLAFEDDGFGD-FQSSAAAPASSTLNNAS 325
Query: 357 XXLNANTNN--ASKDTDLFGD 375
+ + T + A D D F D
Sbjct: 326 LFMGSQTASTAAKNDDDAFDD 346
>Hs7661968 [F] KOG2057 Predicted equilibrative nucleoside transporter protein
Length = 625
Score = 155 bits (391), Expect = 1e-37
Identities = 66/158 (41%), Positives = 111/158 (69%)
Query: 10 LSLYDAKKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEIL 69
L+++ ++ KA NVV NY+E+E+KVREATN++PWG S LM IA+ T+ Y + E++
Sbjct: 2 LNMWKVRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELM 61
Query: 70 GMIFRRFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQG 129
M++ R + WR++YK+L LL YL+++GSER + R ++ ++ LE++H++D G
Sbjct: 62 NMLWSRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHG 121
Query: 130 RDQGINVRNRASQLVKLLESDEQIRQERKKARETLKKY 167
+DQGIN+R + +LV+ + D+++R+ERKKA++ KY
Sbjct: 122 KDQGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKY 159
>Hs7019369 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 551
Score = 146 bits (368), Expect = 6e-35
Identities = 70/147 (47%), Positives = 100/147 (67%), Gaps = 1/147 (0%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R+ +N+V NY+E E KVREAT+N+PWG SS+LM IA TYN EI+ MI++R +
Sbjct: 8 RQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDH 67
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
WR +YKA+ L+EYL+K GSER + N+ V+ L+ F Y+D G+DQG+NVR +
Sbjct: 68 -GKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREK 126
Query: 140 ASQLVKLLESDEQIRQERKKARETLKK 166
A QLV LL ++++R+ER A +T +K
Sbjct: 127 AKQLVALLRDEDRLREERAHALKTKEK 153
>Hs8923678 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 632
Score = 144 bits (364), Expect = 2e-34
Identities = 69/147 (46%), Positives = 101/147 (67%), Gaps = 1/147 (0%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R+ +N+V NY+E E KVREAT+N+PWG S+LM IA T+N E++GM++RR +
Sbjct: 8 RQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLND- 66
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
+ WR +YKAL LL+YL+K GSER R NL ++ L+ F YID G+DQG+NVR +
Sbjct: 67 SGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREK 126
Query: 140 ASQLVKLLESDEQIRQERKKARETLKK 166
Q++ LL+ +E++RQER A +T ++
Sbjct: 127 VKQVMALLKDEERLRQERTHALKTKER 153
>Hs7662468 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 641
Score = 144 bits (363), Expect = 2e-34
Identities = 70/147 (47%), Positives = 101/147 (68%), Gaps = 1/147 (0%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R+ +N+V NY+E E KVREAT+N+PWG SS+LM IA TYN EI+ M+++R +
Sbjct: 8 RQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDH 67
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
WR +YKAL LL+YL+K GSER R N+ ++ L+ F YID G+DQGINVR +
Sbjct: 68 -GKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREK 126
Query: 140 ASQLVKLLESDEQIRQERKKARETLKK 166
+ QLV LL+ +E+++ ER +A +T ++
Sbjct: 127 SKQLVALLKDEERLKAERAQALKTKER 153
>7300848_1 [F] KOG2057 Predicted equilibrative nucleoside transporter protein
Length = 651
Score = 142 bits (358), Expect = 9e-34
Identities = 93/349 (26%), Positives = 155/349 (43%), Gaps = 38/349 (10%)
Query: 28 NYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEKTASEWRQI 87
NYTE E KVREATN++PWG + LM+ +A T++Y E++ M+++R + + WR+
Sbjct: 2 NYTETEGKVREATNDDPWGPTGPLMQELAYSTFSYETFPEVMSMLWKRMLQDNKTNWRRT 61
Query: 88 YKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNRASQLVKLL 147
YK+L LL YLV++GSER + R ++ ++ LE++ + D G+DQGINVR++ +L+ +
Sbjct: 62 YKSLLLLNYLVRNGSERVVTSSREHIYDLRSLENYTFTDEGGKDQGINVRHKVRELIDFI 121
Query: 148 ESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKSTSHGISVSADFDSDDD 207
+ D+++R+ERKKA++ KY +GY+ + G S ++ D
Sbjct: 122 QDDDRLREERKKAKKNKDKY---IGMSSDAMGMRSGGYSGYSGGSGGGGGGSGGYNDGD- 177
Query: 208 EGYQKPLPYGQDNGNGMRASTEEYQPKINEETSDLFDFQDTPGPVSQSRDTNGNGISSHX 267
Y G+ Y K ++ + + D P + + + ++ +
Sbjct: 178 --------YRSSRGDNW------YSDKSADKDRRNYRYNDRASPAEVASEAKPSSLNMNI 223
Query: 268 XXXXXXXXXXXXXXXXQSATPSASTKKSGGLDDLIFSNNNSFATPSHTYVPSATVTPAIA 327
SA P+ S KK DL + N P + +P
Sbjct: 224 RSKTVSSPVSKQPTSTASAKPALSQKKI----DLGAAANFGKPAPGGA---AGIHSPTHR 276
Query: 328 ETSKNSDPFGSLFSSAKNEPFXXXXXXXXXXLNANTNNASKDTDLFGDL 376
+T + D G S AN N S + DL DL
Sbjct: 277 DTPTSVDLMGGASPSPSTS-------------KANNNTQSNNNDLLDDL 312
>At2g43160 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 267
Score = 131 bits (329), Expect = 2e-30
Identities = 76/207 (36%), Positives = 110/207 (52%), Gaps = 19/207 (9%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R+ V +E KV +AT+NEPWG +L+ +AQ + NY E + I+ +I++R ++
Sbjct: 14 REVNKKVLKVPGVEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMVVIWKRLSD- 72
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
T WR +YKAL +LEY+V HGSER ID++R + L F YIDS GRDQG NVR +
Sbjct: 73 TGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKK 132
Query: 140 ASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKSTSHGISVS 199
+ LV L+ E+I + R+KA KY+ +S G S G
Sbjct: 133 SQSLVALVNDKERIAEVRQKAAANRDKYR--------------SSAPGGMYKPSGGYGDK 178
Query: 200 ADFDSDDDE----GYQKPLPYGQDNGN 222
D+ S D+E G ++ Y D+ N
Sbjct: 179 YDYGSRDEERSSYGREREYGYRDDDRN 205
>7295219 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 810
Score = 129 bits (325), Expect = 6e-30
Identities = 63/148 (42%), Positives = 98/148 (65%), Gaps = 2/148 (1%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R +N+ NY++ + KVREAT+N+PWG S+ +M IA+ TYN EI+ MI++R +
Sbjct: 10 RNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDH 69
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
WR +YKAL LLEYL+K GSE+ + N+ ++ L F Y + +G+DQG +VR +
Sbjct: 70 -GKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREK 127
Query: 140 ASQLVKLLESDEQIRQERKKARETLKKY 167
A QLV LL+ DE+++ ER KA++ +++
Sbjct: 128 AKQLVTLLKDDERLKNERVKAQKAKERF 155
>CE26821 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 469
Score = 125 bits (315), Expect = 8e-29
Identities = 94/342 (27%), Positives = 157/342 (45%), Gaps = 38/342 (11%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R+ +NV +N+++ + KVREAT+N+PWG S+ LM IA T+N EI+ ++++R +
Sbjct: 8 RQVKNVAYNFSDAQVKVREATSNDPWGPSTALMSEIADLTHNPMAFTEIMSIVWKRLND- 66
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
+ WR +YK+L LL++L+K G E+ R N+ ++ L+ F +++ RDQG+N+R +
Sbjct: 67 SGKNWRHVYKSLVLLDFLIKCGHEKVAQQCRENVFTIETLKDFQHVE-DNRDQGLNIREK 125
Query: 140 ASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKSTSHGISVS 199
A Q+ LL DE+++ ER + T K+K N H S
Sbjct: 126 AKQITSLLSDDERLKNERTRFILTRNKFKQNNPGPVGAESRRSNRH--------HVTDAS 177
Query: 200 ADFDSDD-------DEGYQKPLPYGQ-----DNGNGMRASTEEYQPKINEETSDLFDFQD 247
D + +D +E Q + + + MR S + EE+ L QD
Sbjct: 178 LDPEYEDARPSTATEEEMQLQIALALSREECEKADEMRKSDDARLQMALEESQKL---QD 234
Query: 248 TPGPVSQSRDTNGNGISSHXXXXXXXXXXXXXXXXXQSATPSASTKKSGGLDD------- 300
+ + T +G + + PS+S+ + G++D
Sbjct: 235 ADRLATTKQGTVSSGQLTQSALDDLLSLGVGELVSGNNDQPSSSS--AWGMNDPWGAPQA 292
Query: 301 --LIFSNNNSFATPSHTYVPSATVTPA--IAETSKNSDPFGS 338
+ +N+ FA P AT T A +A T+ NSDPF S
Sbjct: 293 SASLNTNDQMFANSMSNNDPWATSTVAQPVAATAPNSDPFAS 334
>CE03062 [F] KOG2057 Predicted equilibrative nucleoside transporter protein
Length = 483
Score = 125 bits (315), Expect = 8e-29
Identities = 92/323 (28%), Positives = 148/323 (45%), Gaps = 37/323 (11%)
Query: 16 KKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGM---I 72
+K + + NY + VREATN +PWG + M+ I + T + R E+ + +
Sbjct: 26 RKVTESMNDAIMNYPKAMMDVREATNEDPWGPTGPQMKKICEYTRS-RYMEDFYNVYTPL 84
Query: 73 FRRFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQ 132
F+R E WR++YK+L LL+YL+K+GSERF+ + R ++ LES+ YID +G+DQ
Sbjct: 85 FQRMLENNKDAWRRVYKSLILLDYLLKNGSERFVQEAREKAYELRRLESYKYIDEKGKDQ 144
Query: 133 GINVRNRASQLVKLLESDEQIRQERKKARETLK-KYKXXXXXXXXXXXXNI-NSRAGYTK 190
GIN+R+R Q+++++ DE ++ ER+KA K KY+ + +S +GY
Sbjct: 145 GINIRHRVKQILEMMNDDELLQAERQKANSDDKSKYRGFDQYDMKMSGSSFKSSNSGYDN 204
Query: 191 STSHGISVSADFDSDDDEGYQKPLPYGQDNGNGMRASTEEYQPKINEETSDLFDFQDTPG 250
S S+ D+ Y+ S + +N S F D
Sbjct: 205 KWDKEDSFSSSVTKKYDDQYK-----------SKEVSNFSFSSNVNRSPSPELGFVD-DS 252
Query: 251 PVSQSRDTNGNGISSHXXXXXXXXXXXXXXXXXQSATPSASTKKSGGLDDLIFSNNNSFA 310
D G+ +SS +S+ P A+T KS F ++ A
Sbjct: 253 KKKDDDDGFGDFVSS------------------RSSQP-AATNKSKPNPSKSFFDDPIPA 293
Query: 311 TPSHTYVPSATVTPAIAETSKNS 333
P + PS V P ++ SKN+
Sbjct: 294 IPPPSGAPSNYVAPPLSPVSKNA 316
>At5g11710 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 577
Score = 125 bits (315), Expect = 8e-29
Identities = 70/215 (32%), Positives = 111/215 (51%), Gaps = 4/215 (1%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R+ V EME KV +AT+NEPWG T + IAQ T + E + ++ +++ R +E
Sbjct: 16 REVNLKVLKVPEMEQKVLDATDNEPWGPHGTALAEIAQATKKFSECQMVMSVLWTRLSE- 74
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
T +WR +YKAL +++YL+ +GSER +D++ + + L SF Y++ G+D GINVR +
Sbjct: 75 TGKDWRYVYKALAVIDYLISNGSERAVDEIIEHTYQISSLTSFEYVEPNGKDVGINVRKK 134
Query: 140 ASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKSTSHGISVS 199
A +V LL + E+I + R KA KY + S G +S S
Sbjct: 135 AENIVALLNNKEKISEIRDKAVANRNKYVGLSSTGITYKSGSSASFGGSFQSGSSNFDSY 194
Query: 200 ADFDSDDDEGYQKPLPYGQDNGNGMRASTEEYQPK 234
D DS +D+ + Q + G++ + Y K
Sbjct: 195 KDRDSREDKNDYESF---QKSRRGVKTEEQSYTSK 226
>CE26820 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 467
Score = 122 bits (306), Expect = 9e-28
Identities = 92/342 (26%), Positives = 156/342 (44%), Gaps = 40/342 (11%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R+ +NV +N+++ + KVREAT+N+PWG S+ LM IA T+N EI+ ++++R +
Sbjct: 8 RQVKNVAYNFSDAQVKVREATSNDPWGPSTALMSEIADLTHNPMAFTEIMSIVWKRLND- 66
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
+ WR +YK+L LL++L+K G E+ R N+ ++ L+ F +++ RDQG+N+R +
Sbjct: 67 SGKNWRHVYKSLVLLDFLIKCGHEKVAQQCRENVFTIETLKDFQHVE-DNRDQGLNIREK 125
Query: 140 ASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKSTSHGISVS 199
A Q+ LL DE+++ ER + T K+K N H S
Sbjct: 126 AKQITSLLSDDERLKNERTRFILTRNKFKQNNPGPVGAESRRSNRH--------HVTDAS 177
Query: 200 ADFDSDD-------DEGYQKPLPYGQ-----DNGNGMRASTEEYQPKINEETSDLFDFQD 247
D + +D +E Q + + + MR S + EE+ +D
Sbjct: 178 LDPEYEDARPSTATEEEMQLQIALALSREECEKADEMRKSDDARLQMALEESQ-----KD 232
Query: 248 TPGPVSQSRDTNGNGISSHXXXXXXXXXXXXXXXXXQSATPSASTKKSGGLDD------- 300
+ + T +G + + PS+S+ + G++D
Sbjct: 233 ADRLATTKQGTVSSGQLTQSALDDLLSLGVGELVSGNNDQPSSSS--AWGMNDPWGAPQA 290
Query: 301 --LIFSNNNSFATPSHTYVPSATVTPA--IAETSKNSDPFGS 338
+ +N+ FA P AT T A +A T+ NSDPF S
Sbjct: 291 SASLNTNDQMFANSMSNNDPWATSTVAQPVAATAPNSDPFAS 332
>At3g59290_1 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 392
Score = 122 bits (306), Expect = 9e-28
Identities = 91/321 (28%), Positives = 133/321 (41%), Gaps = 22/321 (6%)
Query: 20 RKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEK 79
R V +E KV +AT+NE WG +L+ IA + NY E + +G++++R ++
Sbjct: 14 RGVNKKVLKVPGIEQKVLDATSNESWGPHGSLLADIAHASRNYHEYQITMGVLWKRLSD- 72
Query: 80 TASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNR 139
+ WR +YKAL +LEY+V HGSER I++V+ + + L F YIDS G+DQG NVR +
Sbjct: 73 SGKNWRHVYKALTVLEYMVGHGSERVIEEVKEHAYQITTLSGFQYIDSSGKDQGSNVRKK 132
Query: 140 ASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKSTSHGISVS 199
A LV L+ E+I + R+KA KY + Y
Sbjct: 133 AQSLVALVNDKERITEVREKAAANRDKYHNSMHRPSGGYGDKYDYEGRY----------- 181
Query: 200 ADFDSDDDEG---YQKPLPYGQDNGNGMRASTEEYQPKINEETSDLFDFQDTPGPVSQSR 256
D DEG Y K YG + + + Y + + D S+S
Sbjct: 182 ----GDRDEGRSSYGKEREYGYRDDDRNSRDGDRYSRDSEDRYGRDGNTDDEYRGRSRSV 237
Query: 257 DTNGNGISSHXXXXXXXXXXXXXXXXXQSATPS--ASTKKSGGLDDLIFSNNNSFATPSH 314
D N NG S P+ S GGL+ N A PS+
Sbjct: 238 D-NYNGSRGRSSDRERPIEDDGQSSSRDSGAPADDHSQDGRGGLERKFSEQNIGAAPPSY 296
Query: 315 TYVPSATVTPAIAETSKNSDP 335
S + +P +E P
Sbjct: 297 EEAVSESRSPVYSERDGGETP 317
>SPCC162.07 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 706
Score = 117 bits (294), Expect = 2e-26
Identities = 66/195 (33%), Positives = 104/195 (52%), Gaps = 5/195 (2%)
Query: 13 YDAKKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMI 72
+ A Y A+N YT+ + KVR AT N+ WG S T M IA+ TY+ E E++ +I
Sbjct: 3 FSALAYNLLAKNFSKGYTDTQIKVRNATTNDSWGPSGTAMAEIAELTYDQNEMLEVMDII 62
Query: 73 FRRFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQ 132
RR +K WR ++K+L LLEY + +GSE + + N+ ++ L F Y+D G DQ
Sbjct: 63 DRRLNDK-GKNWRHVFKSLSLLEYCLHNGSENVVRWAKDNIYIITTLREFVYVDDNGHDQ 121
Query: 133 GINVRNRASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKS- 191
G NVR +A ++ LLE + +++ R +RE + + + + RA Y +S
Sbjct: 122 GQNVRTKAKEITSLLEDEHALKEARGDSRE---RDRDRDRTRSSRFDDDDDDRAPYEESR 178
Query: 192 TSHGISVSADFDSDD 206
S S ++ +D DD
Sbjct: 179 LSRAPSRASRYDDDD 193
>Hs17456254 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 129
Score = 114 bits (286), Expect = 2e-25
Identities = 57/129 (44%), Positives = 84/129 (64%), Gaps = 1/129 (0%)
Query: 23 QNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFTEKTAS 82
+N+V NY+E E KV+EAT+N+PWG SS+LM IA TYN I+ M+++R + + +
Sbjct: 2 KNIVKNYSEAEIKVQEATSNDPWGPSSSLMTEIADLTYNMVAFSGIMSMMWKRLNDHSKN 61
Query: 83 EWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNRASQ 142
W+ +YK L LL+Y +K GSE R + ++ L+ F YID G+DQGINV ++ Q
Sbjct: 62 -WQHVYKELLLLDYPIKTGSECMAQQCREIIFAIQTLKDFQYIDQDGKDQGINVHEKSKQ 120
Query: 143 LVKLLESDE 151
LV LL+ +E
Sbjct: 121 LVALLKDEE 129
>YDL161w [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 454
Score = 96.3 bits (238), Expect = 7e-20
Identities = 51/143 (35%), Positives = 86/143 (59%), Gaps = 1/143 (0%)
Query: 15 AKKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFR 74
+K++ R A+N+V Y+ + VR AT+N+ S + +A+ +Y+ + EI+ M+ +
Sbjct: 2 SKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAEKSYDSADFFEIMDMLDK 61
Query: 75 RFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGI 134
R +K WR I KAL +++YL++ GSE + R NL ++K L+ F + D +G DQG
Sbjct: 62 RLNDK-GKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYIIKTLKEFRHEDDEGIDQGQ 120
Query: 135 NVRNRASQLVKLLESDEQIRQER 157
VR +A +L LL DE++ +ER
Sbjct: 121 IVRVKAKELTALLSDDERLNEER 143
>At3g46540 [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 307
Score = 93.6 bits (231), Expect = 5e-19
Identities = 58/268 (21%), Positives = 129/268 (47%), Gaps = 16/268 (5%)
Query: 7 ITKLSLYDAKKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYRERE 66
+ K + + K+ + A+ + + T ++ EAT+ E G ++ + I++ + + +
Sbjct: 21 LKKQASFFFKEKLKTARLALTDVTPLQLMTEEATDGESCGPNTQTLGSISKAAFEFEDYL 80
Query: 67 EILGMIFRRFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYID 126
I+ ++ +R + WR Y +L ++E+L+ HG E D+ + +++++ +++F ID
Sbjct: 81 AIVEVLHKRLAKFDKRNWRMAYNSLIVVEHLLTHGPESVSDEFQGDIDVISQMQTFQQID 140
Query: 127 SQGRDQGINVRNRASQLVKLLESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRA 186
+G + G+ VR +A +++KLLE E +++ERK+ARE + + +++
Sbjct: 141 EKGFNWGLAVRKKAEKVLKLLEKGELLKEERKRARELSRGIQGFGSFNHKSSSHSLSEHE 200
Query: 187 GYTKSTSH---GISVSADFDSDDDEG----------YQKPL--PYGQDNGNGMRASTEEY 231
+ST + + + ++D DD E + +PL +++ GM+ + +
Sbjct: 201 VLQESTVYRKCNSNFTKNYDEDDQENTMVSPNDANLFPQPLVADPSEESRTGMKENMDPE 260
Query: 232 QPKINEETSDLFDFQDTPGPVSQSRDTN 259
+ N E + L F G D N
Sbjct: 261 DDE-NTEVNPLLGFSKKEGQELAGEDEN 287
>YLR206w [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 613
Score = 91.3 bits (225), Expect = 2e-18
Identities = 48/143 (33%), Positives = 86/143 (59%), Gaps = 1/143 (0%)
Query: 15 AKKYFRKAQNVVFNYTEMEAKVREATNNEPWGASSTLMEHIAQGTYNYREREEILGMIFR 74
+K++ R A+N++ Y+ + VR+AT N+ S ++ +AQ +Y+ + EI+ M+ +
Sbjct: 2 SKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDK 61
Query: 75 RFTEKTASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGI 134
R +K WR + K+L +L+YLV+ GSE + R N ++K L F + + G D+G
Sbjct: 62 RLNDK-GKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQ 120
Query: 135 NVRNRASQLVKLLESDEQIRQER 157
+R +A +LV LL +E++R+ER
Sbjct: 121 IIRVKAKELVSLLNDEERLREER 143
>YLL038c [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 247
Score = 64.3 bits (155), Expect = 3e-10
Identities = 41/138 (29%), Positives = 76/138 (54%), Gaps = 6/138 (4%)
Query: 27 FNYTEMEAKVREATN-NEPWGASSTLMEHIAQGTYNYREREEILGMIFRRFT-----EKT 80
F + E+KV++ATN +E GA+ TLM I+ TY+ + EI+ +I +R +
Sbjct: 10 FIQSPTESKVKQATNEDETSGATGTLMNEISILTYSPKTVREIIQVIRKRLLLGQNRRNS 69
Query: 81 ASEWRQIYKALQLLEYLVKHGSERFIDDVRTNLNLVKMLESFHYIDSQGRDQGINVRNRA 140
Q+ K L L+ YL+ +GS FI ++ N+ L+++LE F D + + +++ +
Sbjct: 70 HRNCIQVMKTLTLVSYLMNNGSNEFIKWLKGNMILIEILEDFQVQDPRDERKAEDIQKLS 129
Query: 141 SQLVKLLESDEQIRQERK 158
++ LL+ D + ++RK
Sbjct: 130 RNVLGLLQDDGLLEKQRK 147
>YDR153c [F] KOG2056 Equilibrative nucleoside transporter protein
Length = 411
Score = 61.6 bits (148), Expect = 2e-09
Identities = 89/417 (21%), Positives = 150/417 (35%), Gaps = 83/417 (19%)
Query: 2 SLEDTITKLSLYDAKKYFRKAQNVVFNYTEMEAKVREATNNEPWGAS------------- 48
SL I L ++D + R AQNV+ Y + +R ATN + WG +
Sbjct: 3 SLSKKIQNLGIHDIRNAARFAQNVIVQYEPYQIDIRRATNTDAWGPTPKHLAKVLRNRYQ 62
Query: 49 -----------STLMEHIAQGTYNYREREEILGMIFRRFTEKTASEWRQIYKALQLLEYL 97
L++HIA N E+ R+ SEWR + K L ++E+L
Sbjct: 63 VPLYLMTEYTLKRLVDHIATRPKNLYEKA-------RKDYVNYGSEWRVVLKCLVVIEFL 115
Query: 98 ---VKHGSERFIDDVRTNL-----NLVKMLESFHYIDSQGRDQGIN---VRNRASQLVKL 146
V G E ++ +R+ L L + + F S I+ +R + +++
Sbjct: 116 LLNVDTGDE--LNQIRSCLLTHKHILTREIAQFKVKFSNDGKMEIHERGIRKKGELILQY 173
Query: 147 LESDEQIRQERKKARETLKKYKXXXXXXXXXXXXNINSRAGYTKSTSHGISVSAD-FDSD 205
LE + +++ER K ++ K + I++ A Y AD FDS+
Sbjct: 174 LEDSQFLKKERAKNKKNALKIR-QQGESSIYNANQISTSASYDNIDDDEFDADADGFDSE 232
Query: 206 DD----EGYQKPLPYGQDNGNGMRASTEEYQPKINE--------------------ETSD 241
D + P+ ++ R+ EE + + E D
Sbjct: 233 MDANNVTNFNVPVETEANSNTRRRSHMEEQRRQRREILREQIKNKEQQRKRKQQQDSIPD 292
Query: 242 LFDFQDTPGPVSQSRDTNGNGISSHXXXXXXXXXXXXXXXXXQSAT-PSASTKKSGG--L 298
L D D+ + NGN + + QS T P + K+ +
Sbjct: 293 LIDLDDSTSTTNNITIDNGNNDNKNNNINSNSDDDDDEFGDFQSETSPDTTAPKTSNSKI 352
Query: 299 DDLIF----SNNNSFATPSHTYVPSA------TVTPAIAETSKNSDPFGSLFSSAKN 345
DDL+ ++ + T +P A A + SK +D F LFS +K+
Sbjct: 353 DDLLDWDGPKSDTDTTAAAQTSLPFAEKKQQKARPQATKDKSKGNDAFSDLFSYSKS 409
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.310 0.127 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,655,461
Number of Sequences: 60738
Number of extensions: 814934
Number of successful extensions: 2188
Number of sequences better than 1.0e-05: 21
Number of HSP's better than 0.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2140
Number of HSP's gapped (non-prelim): 26
length of query: 400
length of database: 30,389,216
effective HSP length: 109
effective length of query: 291
effective length of database: 23,768,774
effective search space: 6916713234
effective search space used: 6916713234
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)