ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1616 check: MH T KOG0583 Signal transduction mechanisms Serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1616 579089 576639 -817
(817 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR059w [T] KOG0583 Serine/threonine protein kinase 343 8e-94
YKL198c [T] KOG0583 Serine/threonine protein kinase 196 2e-49
YKL199c [T] KOG0583 Serine/threonine protein kinase 109 2e-23
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 107 1e-22
YDL214c [D] KOG0590 Checkpoint kinase and related serine/threoni... 105 3e-22
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 104 5e-22
YNL183c [D] KOG0590 Checkpoint kinase and related serine/threoni... 99 3e-20
SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/thr... 96 2e-19
YDL025c [D] KOG0590 Checkpoint kinase and related serine/threoni... 96 3e-19
YOR267c [D] KOG0590 Checkpoint kinase and related serine/threoni... 94 6e-19
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 93 2e-18
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 91 7e-18
At2g30360 [T] KOG0583 Serine/threonine protein kinase 91 7e-18
At4g30960 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
7300413 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 86 2e-16
At5g01810 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 85 4e-16
At4g18700 [T] KOG0583 Serine/threonine protein kinase 85 5e-16
At1g01140 [T] KOG0583 Serine/threonine protein kinase 84 7e-16
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 84 1e-15
At4g14580 [T] KOG0583 Serine/threonine protein kinase 84 1e-15
At2g26980 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
At2g34180 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
At5g45810 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 82 4e-15
At1g30270 [T] KOG0583 Serine/threonine protein kinase 82 4e-15
7296128 [T] KOG0583 Serine/threonine protein kinase 82 4e-15
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 81 6e-15
At5g35410 [T] KOG0583 Serine/threonine protein kinase 81 6e-15
At3g23000 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 80 2e-14
CE16081 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
At5g58380 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
At5g25110 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/thr... 79 4e-14
CE28479 [T] KOG0583 Serine/threonine protein kinase 78 5e-14
At5g01820 [T] KOG0583 Serine/threonine protein kinase 78 5e-14
At2g38490 [T] KOG0583 Serine/threonine protein kinase 78 6e-14
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 77 8e-14
At1g29230 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
At5g07070 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
At5g45820 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
7302570 [R] KOG0586 Serine/threonine protein kinase 76 2e-13
At1g48260 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
7297080 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
7303111 [T] KOG0695 Serine/threonine protein kinase 75 5e-13
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 74 7e-13
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 74 9e-13
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 9e-13
YKL168c [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 1e-12
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 74 1e-12
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 74 1e-12
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 74 1e-12
At2g25090 [T] KOG0583 Serine/threonine protein kinase 73 2e-12
CE27768 [R] KOG0586 Serine/threonine protein kinase 73 2e-12
CE23838 [R] KOG0586 Serine/threonine protein kinase 73 2e-12
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 72 3e-12
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 72 3e-12
7299437 [R] KOG0586 Serine/threonine protein kinase 72 3e-12
CE28218 [D] KOG0588 Serine/threonine protein kinase 72 4e-12
At5g10930 [T] KOG0583 Serine/threonine protein kinase 72 4e-12
7302464 [R] KOG0586 Serine/threonine protein kinase 72 4e-12
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 71 8e-12
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 71 8e-12
At4g24400 [T] KOG0583 Serine/threonine protein kinase 71 8e-12
7294217 [D] KOG0588 Serine/threonine protein kinase 71 8e-12
7303211 [T] KOG4717 Serine/threonine protein kinase 70 1e-11
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 70 2e-11
YJL165c [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 2e-11
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 70 2e-11
At3g17510 [T] KOG0583 Serine/threonine protein kinase 70 2e-11
7295638 [T] KOG0603 Ribosomal protein S6 kinase 70 2e-11
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 69 2e-11
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 69 3e-11
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 69 4e-11
7299438 [R] KOG0586 Serine/threonine protein kinase 69 4e-11
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 68 5e-11
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 68 6e-11
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 67 8e-11
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 67 1e-10
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 67 1e-10
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 67 1e-10
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 67 1e-10
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 67 1e-10
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 67 1e-10
CE02604 [T] KOG0695 Serine/threonine protein kinase 67 1e-10
YCL024w [T] KOG0583 Serine/threonine protein kinase 67 1e-10
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 66 2e-10
7290249 [R] KOG0586 Serine/threonine protein kinase 66 2e-10
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 65 3e-10
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 65 3e-10
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 65 3e-10
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 65 3e-10
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 65 3e-10
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 65 3e-10
YPL150w [T] KOG0583 Serine/threonine protein kinase 65 4e-10
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 65 4e-10
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 65 4e-10
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 65 4e-10
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 65 4e-10
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 65 4e-10
YOR233w [T] KOG0583 Serine/threonine protein kinase 65 5e-10
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 65 5e-10
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 65 5e-10
CE20717 [T] KOG0583 Serine/threonine protein kinase 65 5e-10
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 65 5e-10
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 65 5e-10
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 64 7e-10
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 64 7e-10
CE00847 [T] KOG0583 Serine/threonine protein kinase 64 7e-10
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 64 9e-10
CE17284 [T] KOG0583 Serine/threonine protein kinase 64 9e-10
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 9e-10
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 64 9e-10
YDR507c [D] KOG0588 Serine/threonine protein kinase 64 1e-09
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 64 1e-09
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 64 1e-09
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 64 1e-09
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 64 1e-09
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 64 1e-09
7302861 [T] KOG0696 Serine/threonine protein kinase 64 1e-09
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 2e-09
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 63 2e-09
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 63 2e-09
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 63 2e-09
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 63 2e-09
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 63 2e-09
CE21239 [T] KOG0583 Serine/threonine protein kinase 63 2e-09
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 63 2e-09
7290150 [T] KOG0583 Serine/threonine protein kinase 63 2e-09
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 62 3e-09
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 62 3e-09
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 62 3e-09
CE18454 [T] KOG4717 Serine/threonine protein kinase 62 3e-09
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 62 3e-09
7302913 [T] KOG1345 Serine/threonine kinase 62 3e-09
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 62 4e-09
Hs5803125 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 62 4e-09
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 62 4e-09
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 62 4e-09
Hs13649368 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 5e-09
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 62 5e-09
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 62 5e-09
CE28643 [T] KOG0583 Serine/threonine protein kinase 62 5e-09
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 62 5e-09
CE07458 [T] KOG0583 Serine/threonine protein kinase 62 5e-09
At4g22940 [D] KOG0600 Cdc2-related protein kinase 62 5e-09
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 61 6e-09
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 6e-09
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 61 6e-09
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 61 6e-09
CE24971 [T] KOG0660 Mitogen-activated protein kinase 61 6e-09
CE01583 [T] KOG0660 Mitogen-activated protein kinase 61 6e-09
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 61 6e-09
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 61 8e-09
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 61 8e-09
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 61 8e-09
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 61 8e-09
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 61 8e-09
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 61 8e-09
CE02586 [T] KOG0696 Serine/threonine protein kinase 61 8e-09
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 60 1e-08
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 60 1e-08
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 60 1e-08
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 60 1e-08
At5g44290 [D] KOG0600 Cdc2-related protein kinase 60 1e-08
At1g03740 [D] KOG0600 Cdc2-related protein kinase 60 1e-08
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 60 1e-08
YPL209c [D] KOG0580 Serine/threonine protein kinase 60 1e-08
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 60 1e-08
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 60 1e-08
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 60 1e-08
At5g57630 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
At1g33770 [D] KOG0600 Cdc2-related protein kinase 60 1e-08
7301734 [T] KOG0694 Serine/threonine protein kinase 60 1e-08
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 60 1e-08
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 60 1e-08
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 60 1e-08
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 60 2e-08
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 60 2e-08
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 60 2e-08
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 60 2e-08
CE29298 [T] KOG0690 Serine/threonine protein kinase 60 2e-08
CE27410 [T] KOG0583 Serine/threonine protein kinase 60 2e-08
CE18646 [T] KOG0690 Serine/threonine protein kinase 60 2e-08
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 60 2e-08
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 60 2e-08
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 59 2e-08
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 59 2e-08
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 59 2e-08
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 59 2e-08
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 59 2e-08
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 59 2e-08
At3g01090 [T] KOG0583 Serine/threonine protein kinase 59 2e-08
At1g54610 [D] KOG0600 Cdc2-related protein kinase 59 2e-08
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 59 2e-08
YPL141c [T] KOG0583 Serine/threonine protein kinase 59 3e-08
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 59 3e-08
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 59 3e-08
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 59 3e-08
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 59 3e-08
CE21025 [D] KOG0580 Serine/threonine protein kinase 59 3e-08
At5g39440 [T] KOG0583 Serine/threonine protein kinase 59 3e-08
At5g39420 [D] KOG0600 Cdc2-related protein kinase 59 3e-08
At1g53050 [D] KOG0600 Cdc2-related protein kinase 59 3e-08
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 59 3e-08
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 59 3e-08
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 59 4e-08
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 59 4e-08
CE26422 [D] KOG0600 Cdc2-related protein kinase 59 4e-08
CE17343 [T] KOG0583 Serine/threonine protein kinase 59 4e-08
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 59 4e-08
At2g32850 [T] KOG1989 ARK protein kinase family 59 4e-08
7300106 [T] KOG0690 Serine/threonine protein kinase 59 4e-08
7296451 [D] KOG0600 Cdc2-related protein kinase 59 4e-08
YLR096w [T] KOG0583 Serine/threonine protein kinase 58 5e-08
YKL101w [D] KOG0588 Serine/threonine protein kinase 58 5e-08
SPBC337.04 [R] KOG0586 Serine/threonine protein kinase 58 5e-08
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 58 5e-08
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 58 5e-08
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 58 5e-08
7302860 [T] KOG0696 Serine/threonine protein kinase 58 5e-08
YHR082c [T] KOG0583 Serine/threonine protein kinase 58 7e-08
YDR477w [T] KOG0583 Serine/threonine protein kinase 58 7e-08
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 58 7e-08
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 58 7e-08
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 58 7e-08
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 58 7e-08
At5g50860 [D] KOG0600 Cdc2-related protein kinase 58 7e-08
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 58 7e-08
YLR113w [T] KOG0660 Mitogen-activated protein kinase 57 9e-08
YGR052w [T] KOG0583 Serine/threonine protein kinase 57 9e-08
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 57 9e-08
Hs7662462 [T] KOG1989 ARK protein kinase family 57 9e-08
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 57 9e-08
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 57 9e-08
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 57 9e-08
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 57 9e-08
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 57 9e-08
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 57 9e-08
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 57 9e-08
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 57 9e-08
CE29020 [T] KOG0660 Mitogen-activated protein kinase 57 9e-08
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 57 9e-08
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 57 9e-08
7299793 [T] KOG0583 Serine/threonine protein kinase 57 9e-08
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 57 9e-08
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 57 9e-08
YDR122w [T] KOG0583 Serine/threonine protein kinase 57 1e-07
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 57 1e-07
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 57 1e-07
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 57 1e-07
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 57 1e-07
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 57 1e-07
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 57 1e-07
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 57 1e-07
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 57 1e-07
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 57 1e-07
At5g10270 [D] KOG0600 Cdc2-related protein kinase 57 1e-07
At3g29160 [T] KOG0583 Serine/threonine protein kinase 57 1e-07
7301004 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 57 1e-07
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 57 1e-07
SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2 57 1e-07
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 57 1e-07
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 57 1e-07
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 57 1e-07
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 57 1e-07
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 57 1e-07
At1g09600 [D] KOG0600 Cdc2-related protein kinase 57 1e-07
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 56 2e-07
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 56 2e-07
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 56 2e-07
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 56 2e-07
CE24761 [D] KOG0580 Serine/threonine protein kinase 56 2e-07
At5g64960 [D] KOG0600 Cdc2-related protein kinase 56 2e-07
At4g10010 [D] KOG0600 Cdc2-related protein kinase 56 2e-07
At3g50500 [T] KOG0583 Serine/threonine protein kinase 56 2e-07
7293601 [T] KOG0577 Serine/threonine protein kinase 56 2e-07
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 56 2e-07
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 56 3e-07
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 56 3e-07
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 56 3e-07
At1g78290 [T] KOG0583 Serine/threonine protein kinase 56 3e-07
At1g57700 [D] KOG0600 Cdc2-related protein kinase 56 3e-07
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 56 3e-07
7291043 [T] KOG0660 Mitogen-activated protein kinase 56 3e-07
Hs4885251_1 [T] KOG1989 ARK protein kinase family 56 3e-07
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 56 3e-07
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 55 3e-07
CE27220 [T] KOG0660 Mitogen-activated protein kinase 55 3e-07
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 55 3e-07
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 55 3e-07
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 55 3e-07
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 55 3e-07
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 55 3e-07
At1g18670 [D] KOG0600 Cdc2-related protein kinase 55 3e-07
7297776 [D] KOG0580 Serine/threonine protein kinase 55 3e-07
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 55 4e-07
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 55 4e-07
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 55 4e-07
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 55 4e-07
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 55 4e-07
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 55 4e-07
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 55 4e-07
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 55 4e-07
CE18699 [T] KOG0694 Serine/threonine protein kinase 55 4e-07
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 55 4e-07
At1g74330 [D] KOG0600 Cdc2-related protein kinase 55 4e-07
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 55 4e-07
7299536 [D] KOG0580 Serine/threonine protein kinase 55 4e-07
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 55 4e-07
YPL026c [T] KOG0583 Serine/threonine protein kinase 55 6e-07
YDR247w [T] KOG0583 Serine/threonine protein kinase 55 6e-07
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 55 6e-07
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 55 6e-07
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 55 6e-07
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 55 6e-07
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 55 6e-07
At3g05050 [D] KOG0600 Cdc2-related protein kinase 55 6e-07
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 54 7e-07
YBL016w [T] KOG0660 Mitogen-activated protein kinase 54 7e-07
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 54 7e-07
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 54 7e-07
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 54 7e-07
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 54 7e-07
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 54 7e-07
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 54 7e-07
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 54 7e-07
CE18366 [T] KOG0583 Serine/threonine protein kinase 54 7e-07
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 54 7e-07
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 54 7e-07
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 54 7e-07
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 54 7e-07
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 54 7e-07
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 54 1e-06
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 54 1e-06
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 54 1e-06
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 54 1e-06
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 54 1e-06
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 54 1e-06
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 54 1e-06
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 54 1e-06
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 54 1e-06
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 54 1e-06
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 54 1e-06
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 54 1e-06
At3g63260 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 1e-06
7302048 [J] KOG1035 eIF-2alpha kinase GCN2 54 1e-06
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 54 1e-06
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 54 1e-06
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 54 1e-06
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 54 1e-06
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 54 1e-06
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 54 1e-06
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 54 1e-06
CE28674 [T] KOG0201 Serine/threonine protein kinase 54 1e-06
CE07510 [T] KOG0201 Serine/threonine protein kinase 54 1e-06
At5g66880 [T] KOG0583 Serine/threonine protein kinase 54 1e-06
At5g08590 [T] KOG0583 Serine/threonine protein kinase 54 1e-06
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 54 1e-06
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 54 1e-06
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 54 1e-06
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 53 2e-06
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 53 2e-06
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 53 2e-06
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 53 2e-06
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 53 2e-06
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 53 2e-06
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 53 2e-06
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 53 2e-06
At4g40010 [T] KOG0583 Serine/threonine protein kinase 53 2e-06
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 53 2e-06
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 53 2e-06
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 53 2e-06
7301213 [R] KOG0589 Serine/threonine protein kinase 53 2e-06
YPR161c [D] KOG0600 Cdc2-related protein kinase 53 2e-06
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 53 2e-06
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 53 2e-06
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 53 2e-06
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 53 2e-06
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 53 2e-06
Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 53 2e-06
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 53 2e-06
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 53 2e-06
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 53 2e-06
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 53 2e-06
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 53 2e-06
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 53 2e-06
At2g23030 [T] KOG0583 Serine/threonine protein kinase 53 2e-06
7302050 [T] KOG0986 G protein-coupled receptor kinase 53 2e-06
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 53 2e-06
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 52 3e-06
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 52 3e-06
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 52 3e-06
CE29092 [T] KOG0694 Serine/threonine protein kinase 52 3e-06
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 52 3e-06
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 52 3e-06
At1g71530 [D] KOG0600 Cdc2-related protein kinase 52 3e-06
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 52 3e-06
7298508 [T] KOG1989 ARK protein kinase family 52 3e-06
7294770 [T] KOG0603 Ribosomal protein S6 kinase 52 3e-06
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 52 4e-06
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 52 4e-06
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 52 4e-06
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 52 4e-06
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 52 4e-06
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 52 4e-06
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 4e-06
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 52 4e-06
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 52 4e-06
YNL307c [G] KOG0658 Glycogen synthase kinase-3 52 5e-06
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 52 5e-06
YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 52 5e-06
HsM4758892 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 52 5e-06
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 52 5e-06
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 52 5e-06
Hs21361155 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 52 5e-06
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 52 5e-06
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 52 5e-06
CE06762 [T] KOG0660 Mitogen-activated protein kinase 52 5e-06
CE01554 [T] KOG0986 G protein-coupled receptor kinase 52 5e-06
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 52 5e-06
At3g50310 [T] KOG0198 MEKK and related serine/threonine protein ... 52 5e-06
At1g60940 [T] KOG0583 Serine/threonine protein kinase 52 5e-06
YHR102w [T] KOG0201 Serine/threonine protein kinase 51 6e-06
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 51 6e-06
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 51 6e-06
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 51 6e-06
Hs18677726 [T] KOG1151 Tousled-like protein kinase 51 6e-06
CE05274 [T] KOG0690 Serine/threonine protein kinase 51 6e-06
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 51 6e-06
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 6e-06
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 51 6e-06
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 51 8e-06
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 51 8e-06
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 51 8e-06
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 51 8e-06
CE15612 [T] KOG0690 Serine/threonine protein kinase 51 8e-06
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 51 8e-06
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 51 8e-06
At4g33950 [T] KOG0583 Serine/threonine protein kinase 51 8e-06
At4g32830 [D] KOG0580 Serine/threonine protein kinase 51 8e-06
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 51 8e-06
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 51 8e-06
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 51 8e-06
7301110 [T] KOG0660 Mitogen-activated protein kinase 51 8e-06
>YJR059w [T] KOG0583 Serine/threonine protein kinase
Length = 818
Score = 343 bits (879), Expect = 8e-94
Identities = 200/527 (37%), Positives = 291/527 (54%), Gaps = 36/527 (6%)
Query: 130 SKSRTRGASLLHKDREKDRDMNS--NMHVIKSSSAIPSLASHNTNPFLNSANGRIPLESL 187
+ +R R ++L +++EK+R N N H S+ASH+ F N P
Sbjct: 134 ASTRDRDRAVLDREKEKERARNKERNTHHAGLPQRSNSMASHH---FPNENIVYNPYGIS 190
Query: 188 DVHSRPPTVSQAYHXXXXXXXXXXXXXLGFYQTEGDAKGENILPLPLKNPNDFLPESMQQ 247
H+RP T L FY +G++K +LPLP+ NPNDFLPE M+Q
Sbjct: 191 PNHARPDTA------FADTLNTNKENDLSFYMHDGNSK-IRMLPLPIANPNDFLPEDMKQ 243
Query: 248 PSVMLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRC 307
SV LTDNF F D+ K +G GGSS+V V S YR+K VYALK+ + E+P+ FY RC
Sbjct: 244 YSVHLTDNFVF-DTDNKPIGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRC 302
Query: 308 ITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKP 367
EF+IAK +S++V+I TFY++K P+ + R W F+M+ V+D+F +GW P
Sbjct: 303 SKEFIIAKHLSHNVHITNTFYLLKVPTTTY-TTRGWGFIMELGVKDLFQLMERTGWKNVP 361
Query: 368 LDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPT 427
+EK+C FKQ+A+GI+ H GIAHRD+K ENVL++ G KLTDFGIS + P D T
Sbjct: 362 FNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYT 421
Query: 428 SERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCP 487
S +G GSPP+ PPEVM Y+P MD++ALGI++ ++
Sbjct: 422 SPVKTCQGMIGSPPYTPPEVMYFD---AKKHYPEKFQKPYNPLAMDSYALGIMLITMINN 478
Query: 488 FALFAEAHKDDSKYRHYIAFYEQF-NKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRV 546
F ++ D+++R + Y+ F N +PHFR G ++ GPG+E+ + +A+R+
Sbjct: 479 IIPFIDSCNTDARFREFEVSYDNFINHQNPHFRDKGCHKPGPGSEYSLARNFKNTDATRI 538
Query: 547 CLRLLDPDASTRYTIDDLFNDPWMAKIESCFXXXXXXPIKVPELRKATTXXXXXXXXXXS 606
RL DP+ +TRYT+DDLFNDP+ +IE+C ++VPELRK+T+ S
Sbjct: 539 AWRLADPNPATRYTMDDLFNDPFFQQIETCVEPNDDDLVRVPELRKSTS------TNDFS 592
Query: 607 TGSSFNEENSGLSHSTNPFLESN------------LKSPKIKSKSMI 641
S + + H++NPFL+ +SP +K KS +
Sbjct: 593 ENSLDAPHDQEVIHTSNPFLKKETLTSKPRSMLEIAESPSLKQKSKV 639
>YKL198c [T] KOG0583 Serine/threonine protein kinase
Length = 399
Score = 196 bits (497), Expect = 2e-49
Identities = 115/312 (36%), Positives = 177/312 (55%), Gaps = 11/312 (3%)
Query: 125 SPKLESKSRT--RGASLLHKDREKDRDMNSNMHVIKSSSAIPSLASHN--TNPFLNSANG 180
SPKL + +T R S H K +++ ++ + + S++ N ++ N +N
Sbjct: 60 SPKLPNSLKTSRRANSFAHTTNSKRSLSSASTKILPPAGSSTSISRGNRHSSTSRNLSNS 119
Query: 181 RIPLESLDVHSRPPTVSQAYHXXXXXXXXXXXXXLGFYQTEGDAKGENILPLPLKNPNDF 240
+ E L V++ + + LGFY +GD+K +LP+P+ +PN++
Sbjct: 120 KFSSERL-VYNPYGVSTPSTSLSSVSTSMKKDPDLGFYLHDGDSK-IRMLPIPIVDPNEY 177
Query: 241 LPESMQQPSVMLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETP 300
LP+ M++ S+ L+DNF F D KT+G GGS +V + S YRKK V+ALK+ + +ETP
Sbjct: 178 LPDEMKEASIQLSDNFVFDDEN-KTIGWGGSCEVRKIRSKYRKKDVFALKKLNMIYNETP 236
Query: 301 DHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTL 360
+ FY+ EF+IAK++S+HV+I TF ++K P+ R W F+M+ ++D+F
Sbjct: 237 EKFYNAAPKEFIIAKQLSHHVHITNTFLLVKVPTTVY-TTRGWGFVMELGLRDLFAMIQK 295
Query: 361 SGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST--- 417
SGW L EK+C FKQ+A G++ H GIAHRD+K ENVL++ G KLTDFGIS
Sbjct: 296 SGWRHVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYH 355
Query: 418 YGIKDPEDPTSE 429
+G P P E
Sbjct: 356 HGSTRPVQPCQE 367
>YKL199c [T] KOG0583 Serine/threonine protein kinase
Length = 279
Score = 109 bits (272), Expect = 2e-23
Identities = 68/194 (35%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GSPP+ PPEVM YDP +D + LGI++ LV F E+
Sbjct: 3 GSPPYAPPEVMFYDSKKHYDTELQQP---YDPRALDCYGLGIILMTLVNNVIPFLESCSF 59
Query: 498 DSKYRHYIAFYEQFNK-HSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAS 556
D+ +R Y YE F + H FR G YR GPG E+ + ASRV RL DP+A+
Sbjct: 60 DTGFRDYCDAYENFIRLHDRAFRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLADPEAA 119
Query: 557 TRYTIDDLFNDPWMAKIESCFXXXXXXPIKVPELRKATTXXXXXXXXXXSTGSSFNEENS 616
TRYTIDDLF DPW IE+C K P ++ T G + +
Sbjct: 120 TRYTIDDLFEDPWFQGIETCVDANDKYVCKKPIIKTTT--------YENPRGFHIATDVA 171
Query: 617 GLSHSTNPFLESNL 630
+ ++NPFL++ +
Sbjct: 172 ATTPTSNPFLKNRV 185
>SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 781
Score = 107 bits (266), Expect = 1e-22
Identities = 88/365 (24%), Positives = 157/365 (42%), Gaps = 47/365 (12%)
Query: 228 NILPLPLKNPNDFLPESMQQPSVMLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQV- 286
NI +P K + F+P ++ L+ + D K +G G ++ + V K+
Sbjct: 415 NISEIPRKLKSGFIPPYAKRVVPRLSAKYKLVDE-TKDMGSGATAVIRIVTLKNPKENEK 473
Query: 287 ---YALKRFKL-FKDETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRS 342
+A+K ++ DET + + +E+++ ++ H N++K++ + + +
Sbjct: 474 NLRFAVKAYRRKADDETDGQYIAKLASEWLVQCRME-HPNVVKSYDLCIDSHIFPLYSDT 532
Query: 343 WAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLV 402
W +M C + + C KQI RG+ ++HS GIAHRDIK EN+L+
Sbjct: 533 WCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQILRGLNYIHSQGIAHRDIKPENILI 592
Query: 403 TDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXX 462
++YG L++TDFG +D T+ K G GS P++ PE++
Sbjct: 593 SEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFGSDPYMAPEIL-------------- 638
Query: 463 XXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFN---------- 512
Y+ F D W+ I++ L F +A ++D Y Y + ++N
Sbjct: 639 TPGSYNAFFADMWSTAIVLHCLYFRTYPFRKASQNDQLYAKYCKAWREYNLICDVQNIRI 698
Query: 513 -KHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMA 571
K P+F+ P + P + R+ L +P A R T + N P++
Sbjct: 699 SKTLPYFK--------PVNDLP-------MHMQRLFFCLANPTAEQRITAQEALNLPFVQ 743
Query: 572 KIESC 576
+IE C
Sbjct: 744 EIECC 748
>YDL214c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 699
Score = 105 bits (262), Expect = 3e-22
Identities = 90/341 (26%), Positives = 151/341 (43%), Gaps = 62/341 (18%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHR-CITEFMIAKKVSNHVNII 324
LGEG +V V + K V+ALK ++ K + Y + I+E+ IA + N NI
Sbjct: 367 LGEGSGGKVKLVQRVLDNK-VFALKEYRSKKKRESERKYIKNIISEYCIASTLKNP-NIC 424
Query: 325 KTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCC-FKQIARGIR 383
+T I+ K +++ C D+F + K E+ CC FKQ+ G++
Sbjct: 425 ETLEILYE-------KGKIFQILEYCEYDLFSLVM----SEKMHYEEICCLFKQLINGVK 473
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST---YGIKDPEDPTSERIKIRGYCGSP 440
++H +G++HRD+KL+N +VT G LKL DFG S+ Y + +S+ I+ G GS
Sbjct: 474 YLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPL------SSQMIEANGIVGSD 527
Query: 441 PHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSK 500
P++ PEV + YDP +D W++GI+ F ++ + D +
Sbjct: 528 PYLSPEVFYFN--------------EYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQ 573
Query: 501 YRHYIA--------------FYEQFNKHSPHFRKPGVYRSGPG---AEHPEFSKLGSVEA 543
++ + + + N + + GV GP PE E
Sbjct: 574 FKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPE-------ET 626
Query: 544 SRVCLRLLDPDASTRYTIDDLFNDPWMAKIESCFXXXXXXP 584
++ R+L+ R TI+ + D W+ +IE+C P
Sbjct: 627 HKIMRRILEVSPFRRITINGILQDGWIKEIETCQVVGAASP 667
>YCR008w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 603
Score = 104 bits (260), Expect = 5e-22
Identities = 80/305 (26%), Positives = 128/305 (41%), Gaps = 63/305 (20%)
Query: 282 RKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKR 341
+ +++YA+K FK E+ + + R +EF I+ + +H NI+ T + + K
Sbjct: 345 KSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSL-HHTNIVTTLDLFQDA------KG 397
Query: 342 SWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENV 400
+ +M+ C D+F +G E C FKQ+ RG+ +MH +G+ HRD+K EN+
Sbjct: 398 EYCEVMEYCAGGDLFTLVVAAG--KLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENL 455
Query: 401 LVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR---------GYCGSPPHVPPEVMILS 451
L+T G LK+TDFG SE K+ G CGS P++ PE I
Sbjct: 456 LLTHDGVLKITDFG------------NSECFKMAWEKNIHLSGGVCGSSPYIAPEEYI-- 501
Query: 452 XXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQF 511
+DP +D WA G++ + L++ A KDD Y +Y+ ++
Sbjct: 502 ------------KEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEK 549
Query: 512 NKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMA 571
+ P L V +LDP R + N W
Sbjct: 550 GGYEP------------------IESLKRARCRNVIYSMLDPVPYRRINGKQILNSEWGR 591
Query: 572 KIESC 576
+I+ C
Sbjct: 592 EIKCC 596
>YNL183c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 790
Score = 98.6 bits (244), Expect = 3e-20
Identities = 89/350 (25%), Positives = 146/350 (41%), Gaps = 62/350 (17%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKL-FKDETPDHFYHRCITEFMIAKKVSNHVNII 324
LG G V I K ++A+K F+ F++E+ + + +E+ I + NH NII
Sbjct: 444 LGAGAGGSVKLAQRISDNK-IFAVKEFRTKFENESKRDYVKKITSEYCIGTTL-NHPNII 501
Query: 325 KTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRH 384
+T I+ +M+ C D+F + + +E CCFKQI G+++
Sbjct: 502 ETIEIVYEND-------RILQVMEYCEYDLFAIVMSNKMS---YEEICCCFKQILTGVQY 551
Query: 385 MHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSER-IKIRGYCGSPPHV 443
+HS+G+AHRD+KL+N ++ + G +KL DFG + P S+ ++ G GS P++
Sbjct: 552 LHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVF----SYPFSKNLVEASGIVGSDPYL 607
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC-------------PFAL 490
PEV I + YDP +D W+ I+ ++ F L
Sbjct: 608 APEVCIFA--------------KYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKL 653
Query: 491 FAEAHKDDSKYRHYI-----AFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLG------ 539
F DS Y++ HS +KP S P +G
Sbjct: 654 FCSGRDCDSLSSLVTRTPDPPSYDE--SHSTEKKKP--ESSSNNVSDPNNVNIGPQRLLH 709
Query: 540 --SVEASRVCLRLLDPDASTRYTIDDLFNDPWMAKIESCFXXXXXXPIKV 587
E + R++D + R I+++ DPW+ I+ C KV
Sbjct: 710 SLPEETQHIVGRMIDLAPACRGNIEEIMEDPWIRSIDMCHLVEDGLSFKV 759
>SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 650
Score = 95.9 bits (237), Expect = 2e-19
Identities = 86/340 (25%), Positives = 141/340 (41%), Gaps = 60/340 (17%)
Query: 267 GEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKT 326
G GGS ++M S +++A+K F+ + + Y R +T +H NII+T
Sbjct: 311 GAGGSVRIMKRSS---DGKIFAVKEFRARRPTETEREYARKVTAEFCIGSALHHTNIIET 367
Query: 327 FYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMH 386
I++ + + +M+ DMF +SG T P E +CCFKQ+ G+ ++H
Sbjct: 368 LDIVEE-------NKKFYEVMEYAPYDMFSIV-MSGKMTMP--EVYCCFKQLLSGVAYLH 417
Query: 387 SLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPE 446
S+G+AHRD+KL+N++V +K+ DFG S K P + ++ ++ G GS P++ PE
Sbjct: 418 SMGLAHRDLKLDNLVVDSNCFVKIIDFG-SAVVFKYPFE--ADIVEATGVVGSDPYLAPE 474
Query: 447 VMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILM-------------------FNLVC- 486
++ YDP +D W+ I+ F L C
Sbjct: 475 TLV--------------RKLYDPRAVDIWSSAIIFCCMALRRFPWKYPKLSDNSFRLFCM 520
Query: 487 ---------PFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHP-EFS 536
P + A+ K + + HSP+ + P
Sbjct: 521 KQPSNDAESPSDILADIKKQRLVEQGCEPIRKTDESHSPNSKTDNSSTHKQELYGPWRLL 580
Query: 537 KLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMAKIESC 576
+L E V +L+ D RY I +F D W+ I C
Sbjct: 581 RLLPRETRAVIAHMLELDPVKRYDIHRVFADNWINDISMC 620
>YDL025c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 620
Score = 95.5 bits (236), Expect = 3e-19
Identities = 87/322 (27%), Positives = 143/322 (44%), Gaps = 52/322 (16%)
Query: 262 GRKTLGEGGSSQVMTVHSIYRKKQVYALKRFK---LFKDETPD----HFYHRCITEFMIA 314
GRK LGEG S V V K ++A K F+ L + T ++ + TEF I
Sbjct: 305 GRK-LGEGASGSVSVVERTDGK--LFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIG 361
Query: 315 KKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCC 374
+ +H NI++T ++ ++ +M+ D F+ +S T+ DE C
Sbjct: 362 STL-HHENIVETLDMLTEGD-------TYLLVMEYAPYDFFNLV-MSNLMTQ--DEVNCY 410
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
FKQ+ G+ ++HS+G+AHRD+KL+N +VT G LKL DFG S + P + T +K
Sbjct: 411 FKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFG-SAVVFQYPYEDTI--VKSH 467
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
G GS P++ PE++ YDP D W++ I+ + +V +
Sbjct: 468 GIVGSDPYLAPELL--------------KQTSYDPRVADVWSIAIIFYCMVLKRFPWKAP 513
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
K + +R F E+ R P + +L + + R+L +
Sbjct: 514 KKSFNSFR---LFTEEPEDEDDIVRGPN-----------KILRLLPRHSRTIIGRMLALE 559
Query: 555 ASTRYTIDDLFNDPWMAKIESC 576
R ++D+ D W+ + SC
Sbjct: 560 PKQRVLMNDVVKDDWLVSVPSC 581
>YOR267c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 759
Score = 94.4 bits (233), Expect = 6e-19
Identities = 66/239 (27%), Positives = 112/239 (46%), Gaps = 29/239 (12%)
Query: 267 GEGGSSQVMTVHSIYRKKQVYALKRFKLFK-DETPDHFYHRCITEFMIAKKVSNHVNIIK 325
G GGS +V+ + +A+K F+ K +E+ + +C EF I + +H N+I+
Sbjct: 224 GAGGSVKVLVRPT---DGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTL-HHPNVIE 279
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHM 385
T + S+ + + +M+ C D F + ++ CC KQ+ G++++
Sbjct: 280 TVDVF-----SDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEIN---CCLKQLTEGVKYL 331
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPP 445
HS+G+AHRD+KL+N ++T G LKL DFG + ED + G GS P++ P
Sbjct: 332 HSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVT---MAHGIVGSDPYLAP 388
Query: 446 EVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHY 504
EV+ YDP +D W++GI+ +V + D +R Y
Sbjct: 389 EVI-------------TSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLY 434
>SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 636
Score = 92.8 bits (229), Expect = 2e-18
Identities = 75/319 (23%), Positives = 130/319 (40%), Gaps = 48/319 (15%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQ----VYALKRFKLFKDETPDHFYHRCITEFMIAKKVS 318
++ +G G V H + + +YA+K F+ E+ + R +EF I+ +
Sbjct: 354 QEVIGRGAFGVVRIAHKVDPQNSGSETLYAVKEFRRKPAESQKKYTKRLTSEFCISSSL- 412
Query: 319 NHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQI 378
H N+I T +++ K + +M+ C + ++ +P++ C FKQ+
Sbjct: 413 RHPNVIHTLDLIQDG------KGDYCEVMELCSGGDLYTLIMAAGRLEPMEAD-CFFKQL 465
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCG 438
RG+ ++H +G+AHRD+K EN+L+T G+LK+TDFG E E G CG
Sbjct: 466 MRGVDYLHDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMAWE---KEAHMTCGLCG 522
Query: 439 SPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHK-D 497
S P++ PE +DP +D WA G++ + L+ A K +
Sbjct: 523 SAPYIAPE--------------EYTESEFDPRAVDVWACGVIYMAMRTGRHLWRVAKKSE 568
Query: 498 DSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAST 557
D Y Y+ + + + P L +L P+ +
Sbjct: 569 DEYYSRYLMDRKNESGYEP------------------IEMLERSRCRNTLYNILHPNPTY 610
Query: 558 RYTIDDLFNDPWMAKIESC 576
R T + W+ I C
Sbjct: 611 RLTAKQIMKSEWVRSITLC 629
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 90.9 bits (224), Expect = 7e-18
Identities = 79/305 (25%), Positives = 131/305 (42%), Gaps = 50/305 (16%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
LG+G ++V + +S K V A+K + +TP F R + M NH +IIK
Sbjct: 18 LGKGSYAKVKSAYSERLKFNV-AVKIID--RKKTPTDFVERFLPREMDILATVNHGSIIK 74
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHM 385
T+ I +T S+G R + + D+ + G + + K F+Q++ +++
Sbjct: 75 TYEIFET---SDG--RIYIIMELGVQGDLLEFIKCQGALHEDVARKM--FRQLSSAVKYC 127
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPP 445
H L I HRD+K EN+L+ +KL+DFG S ++ D I + +CGS + P
Sbjct: 128 HDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLR---DSNGRIILSKTFCGSAAYAAP 184
Query: 446 EVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYI 505
EV+ Y P D W+LG++++ +VC DDS R +
Sbjct: 185 EVL--------------QSIPYQPKVYDIWSLGVILYIMVC-----GSMPYDDSDIRKML 225
Query: 506 AFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLF 565
++ P SK + E + R+L PD S R ID++
Sbjct: 226 RIQKEHRVDFPR------------------SKNLTCECKDLIYRMLQPDVSQRLHIDEIL 267
Query: 566 NDPWM 570
+ W+
Sbjct: 268 SHSWL 272
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 90.9 bits (224), Expect = 7e-18
Identities = 83/311 (26%), Positives = 136/311 (43%), Gaps = 58/311 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K LG G ++V R Q A+K K T + E I +++S H NI
Sbjct: 25 KLLGCGAFAKVFHARD-RRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLS-HPNI 82
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQIARG 381
+K +M T +S F + V+ ++F+ + G ++ L ++ F+Q+
Sbjct: 83 VKLHEVMAT--------KSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRY--FQQLISA 132
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ + H+ G+ HRD+K EN+L+ + G LK++DFG+S + D P + CG+P
Sbjct: 133 VGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLS--ALTDQIRPDG---LLHTLCGTPA 187
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+V PE++ Y+ K+D W+ GI++F LV + F D +
Sbjct: 188 YVAPEIL--------------SKKGYEGAKVDVWSCGIVLFVLVAGYLPF----NDPNVM 229
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
Y Y+ G YR F + S + R RLLD + TR TI
Sbjct: 230 NMYKKIYK------------GEYR---------FPRWMSPDLKRFVSRLLDINPETRITI 268
Query: 562 DDLFNDPWMAK 572
D++ DPW +
Sbjct: 269 DEILKDPWFVR 279
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 86.7 bits (213), Expect = 1e-16
Identities = 60/202 (29%), Positives = 94/202 (45%), Gaps = 52/202 (25%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+Q+ + HS G+ HRD+K EN+L+ + G LK+TDFG+S + +E +K
Sbjct: 127 FQQLISAVDFCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLSAF---------TEHLKQD 177
Query: 435 GY----CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFAL 490
G CG+P +V PEV++ YD K D W+ G+++F L+ +
Sbjct: 178 GLLHTTCGTPAYVAPEVIL--------------KKGYDGAKADLWSCGVILFVLLAGYLP 223
Query: 491 FAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRL 550
F +DD+ Y Y F+ PG S +A R+ +L
Sbjct: 224 F----QDDNLVNMYRKIYR------GDFKCPGWLSS---------------DARRLVTKL 258
Query: 551 LDPDASTRYTIDDLFNDPWMAK 572
LDP+ +TR TI+ + + PW K
Sbjct: 259 LDPNPNTRITIEKVMDSPWFKK 280
>7300413 [T] KOG0583 Serine/threonine protein kinase
Length = 302
Score = 86.7 bits (213), Expect = 1e-16
Identities = 85/317 (26%), Positives = 136/317 (42%), Gaps = 63/317 (19%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCIT-EFMIAKKVSNHVNII 324
+GEG + V+T L + K + P F ++ E I K+ +H NII
Sbjct: 34 IGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPTDFVNKFFPRELEILTKI-DHSNII 92
Query: 325 KTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEK----WCCFKQIAR 380
+ I++ GPK + F+ D+ + SG P+DEK W F Q+++
Sbjct: 93 QIHSILQ-----RGPK-IFIFMRYAENGDLLSHIKRSG----PIDEKQSKIW--FFQMSK 140
Query: 381 GIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSP 440
++++H+L IAHRD+K EN+L++ +KL DFG + Y D +K YCGS
Sbjct: 141 ALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARY----CRDDNGREMKSETYCGSA 196
Query: 441 PHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMF---NLVCPFALFAEAHKD 497
+ PEV+ YDP D W+LG+++F N PF D
Sbjct: 197 AYAAPEVVC--------------GRPYDPKLADAWSLGVILFIMMNAKMPF--------D 234
Query: 498 DSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAST 557
DS + +Q N+ RK + S +A LL+P+A
Sbjct: 235 DSNLTKLLE--DQRNRKFAFRRK--------------LQETISAQAKATVSVLLEPEAHA 278
Query: 558 RYTIDDLFNDPWMAKIE 574
R+ + ++ N W+ +E
Sbjct: 279 RWNLREILNCAWLRTVE 295
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 86.3 bits (212), Expect = 2e-16
Identities = 70/258 (27%), Positives = 113/258 (43%), Gaps = 39/258 (15%)
Query: 254 DNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLF-KDETPDHFYHRCITEFM 312
D++ F ++ LGEG ++V+ V + +++A+K + KDE F E
Sbjct: 16 DSYEFIEN----LGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDEC---FMESIKRECS 68
Query: 313 IAKKVSN--HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDE 370
I K++S H+N+I F + P+ L D+F G DE
Sbjct: 69 IQKRLSKSRHLNMIHLF------EIRTNPENYQLILSYADGGDLFEKINQHGGLGS--DE 120
Query: 371 KWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST-YGIKDPEDPTSE 429
FKQ+ G+R +H G+ HRDIK EN+L+T G LK+ DFG +T + E
Sbjct: 121 AHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNGAEQ---- 176
Query: 430 RIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFA 489
+ YCGSPP++ PEV+ Y +D W+ G+++ ++
Sbjct: 177 --MLNAYCGSPPYIAPEVL--------------TGIDYRGPAVDIWSAGVVLIAMIAGAV 220
Query: 490 LFAEAHKDDSKYRHYIAF 507
+ +A D Y +F
Sbjct: 221 PWEQADHFDIFQSRYCSF 238
Score = 69.7 bits (169), Expect = 2e-11
Identities = 45/138 (32%), Positives = 70/138 (50%), Gaps = 26/138 (18%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVT------DYGALKLTDFGISTYGIKDPEDPTS 428
FKQ+ +G++ +H GI HRDIKLEN+L+ D G LK+TDFG++T KD
Sbjct: 450 FKQLIKGLKFIHEQGIVHRDIKLENLLLVYSESEDDPGTLKITDFGLATKYRKD-----G 504
Query: 429 ERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPF 488
E I + CGS P+ PEV Y +D W+ G+++ ++
Sbjct: 505 EEIMLSEDCGSKPYAAPEVC--------------TGNDYRGPPVDIWSAGVVLMTMLVGE 550
Query: 489 ALFAEAHKD-DSKYRHYI 505
+ A+K+ D+ Y ++I
Sbjct: 551 HSWKVANKEKDAAYSNWI 568
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 86.3 bits (212), Expect = 2e-16
Identities = 64/262 (24%), Positives = 113/262 (42%), Gaps = 59/262 (22%)
Query: 314 AKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWC 373
A ++ H NI++ +M T K F+M+ +G + + K+
Sbjct: 63 AMRLLRHPNIVELHEVMAT-------KSKIYFVMEHVKGGELFNKVSTGKLREDVARKY- 114
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKI 433
F+Q+ R + HS G+ HRD+K EN+L+ ++G LK++DFG+S +D +
Sbjct: 115 -FQQLVRAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGL-----L 168
Query: 434 RGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAE 493
CG+P +V PEV+ YD FK D W+ G+++F L+ + F +
Sbjct: 169 HTTCGTPAYVAPEVI--------------SRNGYDGFKADVWSCGVILFVLLAGYLPFRD 214
Query: 494 AHKDDSKYRHYIAFYEQFNKHS---PHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRL 550
+ + + Y++ K P++ PG A R+ R+
Sbjct: 215 S--------NLMELYKKIGKAEVKFPNWLAPG--------------------AKRLLKRI 246
Query: 551 LDPDASTRYTIDDLFNDPWMAK 572
LDP+ +TR + + + W K
Sbjct: 247 LDPNPNTRVSTEKIMKSSWFRK 268
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 85.1 bits (209), Expect = 4e-16
Identities = 74/311 (23%), Positives = 133/311 (41%), Gaps = 51/311 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K++G+G QV + + A+K+ +F P F + E+ I K + H NI
Sbjct: 10 KSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFG--APKEFLEQIQQEYYIQKNMK-HKNI 66
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K + + + +L Q+ V + + P+++ KQ+ G++
Sbjct: 67 VKMYGMSMDTE--------FCYLFQEFVTGGDLFEKIDFENGMPVNQVKGYLKQLMSGLK 118
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
++H GI HRDIK +N+L+ ALK+ DFG+ST I D ++ I + G+ P +
Sbjct: 119 YIHGCGIVHRDIKPDNLLINSSDALKIADFGLSTRFIVDDKE-----ILLHERIGTTPFM 173
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRH 503
PE+ + +D W+ GIL+F+L+ + E + D Y
Sbjct: 174 APELF--------------AKKKHRGPPVDIWSAGILVFSLLTGNLPWDEPKESDILYSQ 219
Query: 504 YIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDD 563
++ NK S + G+ S R +LL + + R TI++
Sbjct: 220 WMN-----NKTSKNCIWYGL----------------STPVVRFLKKLLKENVNERATIEE 258
Query: 564 LFNDPWMAKIE 574
+ +DPW+ +E
Sbjct: 259 IESDPWLEDLE 269
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 84.7 bits (208), Expect = 5e-16
Identities = 76/334 (22%), Positives = 139/334 (40%), Gaps = 64/334 (19%)
Query: 241 LPESMQQPSVMLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVY--ALKRFKLFKDE 298
LP+ P ++ + K LG G ++V ++ + V + + K+ K
Sbjct: 11 LPKERSSPQALILGRYEMG----KLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGG 66
Query: 299 TPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYT 358
H E I ++V H NI++ F +M T K F+M+
Sbjct: 67 LIAHIKR----EISILRRV-RHPNIVQLFEVMAT-------KAKIYFVMEYVRGGELFNK 114
Query: 359 TLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTY 418
G + + K+ F+Q+ + H+ G+ HRD+K EN+L+ + G LK++DFG+S
Sbjct: 115 VAKGRLKEEVARKY--FQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAV 172
Query: 419 GIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALG 478
+ +D +CG+P +V PEV+ YD K+D W+ G
Sbjct: 173 SDQIRQDGL-----FHTFCGTPAYVAPEVL--------------ARKGYDAAKVDIWSCG 213
Query: 479 ILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKL 538
+++F L+ + F + R+ +A Y++ + FR P +
Sbjct: 214 VILFVLMAGYLPFHD--------RNVMAMYKKI--YRGEFRCPRWF-------------- 249
Query: 539 GSVEASRVCLRLLDPDASTRYTIDDLFNDPWMAK 572
S E +R+ +LL+ + R+T ++ + W K
Sbjct: 250 -STELTRLLSKLLETNPEKRFTFPEIMENSWFKK 282
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 84.3 bits (207), Expect = 7e-16
Identities = 73/311 (23%), Positives = 131/311 (41%), Gaps = 59/311 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQ--VYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
+TLGEG ++V + Q + L R K+F+ + + T K+ H
Sbjct: 23 RTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREIST-----MKLIKHP 77
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
N+++ +M + ++ +++ + V + ++ DE F+Q+
Sbjct: 78 NVVEIIEVMAS--------KTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINA 129
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ + HS G+ HRD+K EN+++ G LK++DFG+S + + ED + CG+P
Sbjct: 130 VDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGL-----LHTACGTPN 184
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+V PEV+ YD D W+ G+++F L+ + F E
Sbjct: 185 YVAPEVL--------------SDKGYDGAAADVWSCGVILFVLMAGYLPFDEP------- 223
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
+ + Y++ K F P + G A RV R+L+P+ TR +I
Sbjct: 224 -NLMTLYKRICK--AEFSCPPWFSQG---------------AKRVIKRILEPNPITRISI 265
Query: 562 DDLFNDPWMAK 572
+L D W K
Sbjct: 266 AELLEDEWFKK 276
>SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 461
Score = 83.6 bits (205), Expect = 1e-15
Identities = 82/322 (25%), Positives = 134/322 (41%), Gaps = 32/322 (9%)
Query: 264 KTLGEGGSSQVMTV---HSIYRKKQVYALKRFKLFKDETPDHFYHRC--ITEFMIAKKVS 318
K++ +G +S + V I K YA K ++ K + E+ I K+
Sbjct: 124 KSIAKGATSTIKVVTHRDKITDAKIYYAAKVYRKTKTSHKKRLNTMVYFLREWSIQPKL- 182
Query: 319 NHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCFKQ 377
+H NI+K T + + + + C Q D+F L++K C KQ
Sbjct: 183 DHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEK---VLTLEDKCCYLKQ 239
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I + + ++ S IAHRD+K EN+L+ G LKLTDFG S + +P D S R + G
Sbjct: 240 ILQAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEI-VGNPGDNESIRF-VSGAV 297
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GS ++ PE Y D W+ GIL+ L + F + K
Sbjct: 298 GSLAYLAPEAF--------------HENEYCGLLADRWSCGILLKVLFTGYFPFKTSVKT 343
Query: 498 DSKYRHYIAFYEQ---FNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
D Y Y++ + + V + P + + G A ++ L LL+PD
Sbjct: 344 DLYYSKYMSILTDTCGISSTDESSFQTEVIKQIPTLQPLRYIPEG---AKKIILSLLNPD 400
Query: 555 ASTRYTIDDLFNDPWMAKIESC 576
+ R ++D + W+ K++ C
Sbjct: 401 SQNRPSLDSILGTAWVRKLDCC 422
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 83.6 bits (205), Expect = 1e-15
Identities = 79/310 (25%), Positives = 132/310 (42%), Gaps = 56/310 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYH-RCITEFMIAKKVSNHVN 322
+ LG G ++V SI + V A+K K +T D R I E +++ NH N
Sbjct: 25 RRLGSGSFAKVHVARSISTGELV-AIKIID--KQKTIDSGMEPRIIREIEAMRRLHNHPN 81
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
++K +M T S + + + ++F G + ++ F+Q+A +
Sbjct: 82 VLKIHEVMATKS------KIYLVVEYAAGGELFTKLIRFGRLNESAARRY--FQQLASAL 133
Query: 383 RHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
H GIAHRD+K +N+L+ G LK++DFG+S PE ++ + + CG+P +
Sbjct: 134 SFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSAL----PEHRSNNGL-LHTACGTPAY 188
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYR 502
PEV+ YD K D W+ G+ +F L+ + F +A
Sbjct: 189 TAPEVI--------------AQRGYDGAKADAWSCGVFLFVLLAGYVPFDDA-------- 226
Query: 503 HYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTID 562
+ +A Y + +K YR F S A + +LLDP+ TR +I+
Sbjct: 227 NIVAMYRKIHKRD--------YR---------FPSWISKPARSIIYKLLDPNPETRMSIE 269
Query: 563 DLFNDPWMAK 572
+ W K
Sbjct: 270 AVMGTVWFQK 279
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 83.2 bits (204), Expect = 1e-15
Identities = 75/309 (24%), Positives = 135/309 (43%), Gaps = 55/309 (17%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+T+GEG ++V + + V ALK L K++ H I + K+ H N+
Sbjct: 18 RTIGEGTFAKVKFARNSETGEPV-ALKI--LDKEKVLKHKMAEQIRREIATMKLIKHPNV 74
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
++ + +M + ++ F++ + V + + DE F+Q+ +
Sbjct: 75 VQLYEVMAS--------KTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVD 126
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
+ HS G+ HRD+K EN+L+ YG LK++DFG+S + +D + CG+P +V
Sbjct: 127 YCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGL-----LHTSCGTPNYV 181
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRH 503
PEV+ YD D W+ G++++ L+ + F DDS +
Sbjct: 182 APEVL--------------NDRGYDGATADMWSCGVVLYVLLAGYLPF-----DDS---N 219
Query: 504 YIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDD 563
+ Y++ + G + P S+ A ++ R+LDP+ TR T +
Sbjct: 220 LMNLYKKISS--------GEFNCPPWL---------SLGAMKLITRILDPNPMTRVTPQE 262
Query: 564 LFNDPWMAK 572
+F D W K
Sbjct: 263 VFEDEWFKK 271
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 82.8 bits (203), Expect = 2e-15
Identities = 85/348 (24%), Positives = 148/348 (42%), Gaps = 78/348 (22%)
Query: 236 NPNDFLPESMQQPSV----MLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVY--AL 289
N PES + P +L D + K LG G ++V +I+ + V +
Sbjct: 33 NKETSTPESPRSPRTPQGSILMDKYEIG----KLLGHGSFAKVYLARNIHSGEDVAIKVI 88
Query: 290 KRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQ 349
+ K+ K H E I ++V H I+ +M T ++ +++ +
Sbjct: 89 DKEKIVKSGLAGHIKR----EISILRRV-RHPYIVHLLEVMAT--------KTKIYIVME 135
Query: 350 CVQDMFHYTTLS-GWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGAL 408
V+ Y T++ G + ++ F+Q+ + HS G+ HRD+KLEN+L+ D G +
Sbjct: 136 YVRGGELYNTVARGRLREGTARRY--FQQLISSVAFCHSRGVYHRDLKLENLLLDDKGNV 193
Query: 409 KLTDFGISTYGIKDPEDPTSERIKIRG----YCGSPPHVPPEVMILSXXXXXXXXXXXXX 464
K++DFG+S SE++K G +CG+P ++ PEV+
Sbjct: 194 KVSDFGLSV---------VSEQLKQEGICQTFCGTPAYLAPEVL--------------TR 230
Query: 465 XXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVY 524
Y+ K D W+ G+++F L+ + F DD ++ + Y + K F+ P
Sbjct: 231 KGYEGAKADIWSCGVILFVLMAGYLPF-----DD---KNILVMYTKIYK--GQFKCP--- 277
Query: 525 RSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMAK 572
K S E +R+ R+LD + TR TI ++ W K
Sbjct: 278 ------------KWFSPELARLVTRMLDTNPDTRITIPEIMKHRWFKK 313
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 82.4 bits (202), Expect = 3e-15
Identities = 66/263 (25%), Positives = 114/263 (43%), Gaps = 54/263 (20%)
Query: 310 EFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLD 369
E I ++V H NI++ F +M T K F+M+ G + +
Sbjct: 76 EISILRRV-RHPNIVQLFEVMAT-------KSKIYFVMEYVKGGELFNKVAKGRLKEEMA 127
Query: 370 EKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSE 429
K+ F+Q+ + H G+ HRD+K EN+L+ + G LK++DFG+S + +D
Sbjct: 128 RKY--FQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGL-- 183
Query: 430 RIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFA 489
+CG+P +V PEV+ YD K+D W+ G+++F L+ F
Sbjct: 184 ---FHTFCGTPAYVAPEVL--------------ARKGYDGAKVDIWSCGVILFVLMAGFL 226
Query: 490 LFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLR 549
F + R+ +A Y++ + FR P + VE +R+ +R
Sbjct: 227 PFHD--------RNVMAMYKKI--YRGDFRCPRWF---------------PVEINRLLIR 261
Query: 550 LLDPDASTRYTIDDLFNDPWMAK 572
+L+ R+T+ D+ W K
Sbjct: 262 MLETKPERRFTMPDIMETSWFKK 284
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 81.6 bits (200), Expect = 4e-15
Identities = 89/358 (24%), Positives = 142/358 (38%), Gaps = 68/358 (18%)
Query: 219 QTEGDAKGENILPLPLKNPNDFLPESMQQPSVMLTDNFAFADSG----RKTLGEGGSSQV 274
QTE +GE P L P + L + M Q ++ + G R +G G SQV
Sbjct: 30 QTESSKEGEEGQPRQL-TPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQV 88
Query: 275 -MTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTP 333
+ +HS+ ++K K+ D R ++ + + + +H NII+ + +++T
Sbjct: 89 KLGIHSLTKEKVA-----IKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETL 143
Query: 334 SVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAH 392
S + +M+ ++F + G ++P E F QI ++HMH I H
Sbjct: 144 SKLH-------LVMEYAGGGELFGKISTEGKLSEP--ESKLIFSQIVSAVKHMHENQIIH 194
Query: 393 RDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSX 452
RD+K ENV T +K+ DFG ST K + +CGSPP+ PE+
Sbjct: 195 RDLKAENVFYTSNTCVKVGDFGFSTVSKKGE--------MLNTFCGSPPYAAPELF---- 242
Query: 453 XXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFN 512
Y +D WALG+L++ +V F + +K + I
Sbjct: 243 ----------RDEHYIGIYVDIWALGVLLYFMVTGTMPFRA--ETVAKLKKSIL------ 284
Query: 513 KHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWM 570
G Y P P R+ +L + RY ID + ND WM
Sbjct: 285 --------EGTYSVPPHVSEP---------CHRLIRGVLQQIPTERYGIDCIMNDEWM 325
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 81.6 bits (200), Expect = 4e-15
Identities = 75/311 (24%), Positives = 132/311 (42%), Gaps = 61/311 (19%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVY--ALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
+TLGEG ++V ++ V + + K+ K++ T K+ H
Sbjct: 35 RTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREIST-----MKLIKHP 89
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
N+I+ F +M + ++ + + + V + +S DE F+Q+
Sbjct: 90 NVIRMFEVMAS--------KTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINA 141
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ + HS G+ HRD+K EN+L+ GALK++DFG+S P E + CG+P
Sbjct: 142 VDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSAL-------PQQEDGLLHTTCGTPN 194
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+V PEV+ YD K D W+ G+++F L+ + F ++
Sbjct: 195 YVAPEVI--------------NNKGYDGAKADLWSCGVILFVLMAGYLPFEDS------- 233
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
+ + Y++ K F P P F S A ++ R+LDP+ +TR T
Sbjct: 234 -NLTSLYKKIFK--AEFTCP-----------PWF----SASAKKLIKRILDPNPATRITF 275
Query: 562 DDLFNDPWMAK 572
++ + W K
Sbjct: 276 AEVIENEWFKK 286
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 81.6 bits (200), Expect = 4e-15
Identities = 69/228 (30%), Positives = 107/228 (46%), Gaps = 44/228 (19%)
Query: 266 LGEGGSSQV-MTVHSIYRKK---QVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
+G G S+V + VH + R K +V L R L D R ++ + + +H
Sbjct: 50 IGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGL------DAKALRMLSSEIATLECVHHP 103
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCC--FKQ 377
NI++ F +++T +L+ + ++ +++++ T G PL E KQ
Sbjct: 104 NILRLFEVVET--------LGRVYLVTEWIRGGELYNHITQGG----PLREIHAAPLLKQ 151
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
+ ++HMHSLG HRDIK ENVL+ LKL DFG ST I + T K+ +C
Sbjct: 152 LLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLI----NGTGANQKLDTFC 207
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
GSPP+ PE+ Y +D WALGIL++ +V
Sbjct: 208 GSPPYAAPELF--------------SDDHYIGAPVDVWALGILLYFMV 241
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 81.3 bits (199), Expect = 6e-15
Identities = 78/307 (25%), Positives = 134/307 (43%), Gaps = 54/307 (17%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
LGEG ++V + +S K V A+K + + P F + + + + NH +IIK
Sbjct: 18 LGEGSYAKVKSAYSERLKFNV-AIKIID--RKKAPADFLEKFLPREIEILAMLNHCSIIK 74
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCFKQIARGIRH 384
T+ I +T S+G +M+ VQ D+ G + DE F Q++ I++
Sbjct: 75 TYEIFET---SHGKVY---IVMELAVQGDLLELIKTRGALHE--DEARKKFHQLSLAIKY 126
Query: 385 MHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKI-RGYCGSPPHV 443
H L + HRD+K +N+L+ +KL+DF S ++D S R+ + + +CGSP +
Sbjct: 127 CHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRD----DSGRMALSKTFCGSPAYA 182
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRH 503
PEV+ Y P D W+LG++++ +VC DDS +
Sbjct: 183 APEVL--------------QGIPYQPKVYDIWSLGVILYIMVC-----GSMPYDDSNIKK 223
Query: 504 YIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDD 563
+ ++ + P SK + E + +L PD + R ID+
Sbjct: 224 MLRIQKEHRVNFPR------------------SKHLTGECKDLIYHMLQPDVNRRLHIDE 265
Query: 564 LFNDPWM 570
+ + WM
Sbjct: 266 ILSHCWM 272
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 81.3 bits (199), Expect = 6e-15
Identities = 66/257 (25%), Positives = 106/257 (40%), Gaps = 60/257 (23%)
Query: 316 KVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF 375
K+ H NI++ + ++ +PS + + L ++F G + K+ F
Sbjct: 64 KIVRHPNIVRLYEVLASPS------KIYIVLEFVTGGELFDRIVHKGRLEESESRKY--F 115
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+Q+ + H H G+ HRD+K EN+L+ G LK++DFG+S P +R
Sbjct: 116 QQLVDAVAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSAL-------PQEGVELLRT 168
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
CG+P +V PEV+ YD D W+ G+++F ++ + F+E
Sbjct: 169 TCGTPNYVAPEVL--------------SGQGYDGSAADIWSCGVILFVILAGYLPFSETD 214
Query: 496 KDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEH---PEFSKLGSVEASRVCLRLLD 552
PG+YR AE P F S E + R+LD
Sbjct: 215 ------------------------LPGLYRKINAAEFSCPPWF----SAEVKFLIHRILD 246
Query: 553 PDASTRYTIDDLFNDPW 569
P+ TR I + DPW
Sbjct: 247 PNPKTRIQIQGIKKDPW 263
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 80.1 bits (196), Expect = 1e-14
Identities = 77/311 (24%), Positives = 133/311 (42%), Gaps = 59/311 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+ LG G ++V SI ++ A+K + K R I E +++ +H NI
Sbjct: 29 RRLGSGSFAKVHLARSI-ESDELVAVKIIEK-KKTIESGMEPRIIREIDAMRRLRHHPNI 86
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQIARG 381
+K +M T +S +L+ + ++F G + ++ F+Q+A
Sbjct: 87 LKIHEVMAT--------KSKIYLVMELASGGELFSKVLRRGRLPESTARRY--FQQLASA 136
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+R H G+AHRD+K +N+L+ + G LK++DFG+S PE + + CG+P
Sbjct: 137 LRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSAL----PEH--LQNGLLHTACGTPA 190
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+ PEV+ YD K D W+ G+++F L L + DDS
Sbjct: 191 YTAPEVI--------------SRRGYDGAKADAWSCGVILFVL-----LVGDVPFDDS-- 229
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
+ A Y + ++ YR F S +A + ++LDP+ TR +I
Sbjct: 230 -NIAAMYRKIHRRD--------YR---------FPSWISKQAKSIIYQMLDPNPVTRMSI 271
Query: 562 DDLFNDPWMAK 572
+ + W K
Sbjct: 272 ETVMKTNWFKK 282
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 79.7 bits (195), Expect = 2e-14
Identities = 73/308 (23%), Positives = 130/308 (41%), Gaps = 55/308 (17%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+GEG S+V S +++V A+K + K P+ F R + + + +H NI
Sbjct: 14 KTIGEGTYSKVKEAFSKKHQRKV-AIK--VIDKMGGPEEFIQRFLPRELQIVRTLDHKNI 70
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I+ + ++++ L+ + + + + P F+Q+ IR
Sbjct: 71 IQVYEMLESADGK-------ICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIR 123
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
+ H G+AHRD+K EN L+ + LKLTDFG + P S R + +CGS +
Sbjct: 124 YCHGCGVAHRDLKCENALLQGFN-LKLTDFGFAKV------LPKSHRELSQTFCGSTAYA 176
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRH 503
PEV+ +D K D W++G++++ ++C F DD+
Sbjct: 177 APEVL--------------QGIPHDSKKGDVWSMGVVLYVMLCASLPF-----DDTDIPK 217
Query: 504 YIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDD 563
+ ++ G P + S + + RLL+PD R +I++
Sbjct: 218 ML------------------WQQQKGVSFPTHLSI-SADCQDLLKRLLEPDMILRPSIEE 258
Query: 564 LFNDPWMA 571
+ PW+A
Sbjct: 259 VSWHPWLA 266
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 79.0 bits (193), Expect = 3e-14
Identities = 69/233 (29%), Positives = 102/233 (43%), Gaps = 47/233 (20%)
Query: 264 KTLGEGGSSQV-MTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
K LG G S+V + VH + ++K K+ D + ++ + A + NH N
Sbjct: 53 KELGAGNFSKVKLGVHQLTKEKVAV-----KIMDKAKMDAKAQKLLSREIQAMEEMNHPN 107
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWAT----KPLDEKWCCFKQI 378
I+K F +++T + R + +++ Y G T KPL F QI
Sbjct: 108 IVKLFEVVETLT------RVHLVIEYASGGELYTYVHERGKLTEGDAKPL------FAQI 155
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCG 438
+ HMHS I HRDIK ENV+ + +KL DFG S + D E +R +CG
Sbjct: 156 VSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSC--LVDREQ------MLRTFCG 207
Query: 439 SPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL---VCPF 488
SPP+ PE+ Y +D WALG+L+F + V PF
Sbjct: 208 SPPYAAPELF--------------QDTSYAGELVDVWALGVLLFFMLIGVTPF 246
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 79.0 bits (193), Expect = 3e-14
Identities = 82/326 (25%), Positives = 134/326 (40%), Gaps = 61/326 (18%)
Query: 247 QPSVMLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHR 306
+PSV LTD + D GR LG+G ++V SI + V A+K K++
Sbjct: 4 KPSV-LTDKY---DVGR-LLGQGTFAKVYYGRSILTNQSV-AIKMID--KEKVMKVGLIE 55
Query: 307 CITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATK 366
I + +++ H N+++ + +M T K F+M+ C G
Sbjct: 56 QIKREISVMRIARHPNVVELYEVMAT-------KTRIYFVMEYCKGGELFNKVAKGKLRD 108
Query: 367 PLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDP 426
D W F Q+ + HS + HRDIK EN+L+ D LK++DFG+S +D
Sbjct: 109 --DVAWKYFYQLINAVDFCHSREVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDG 166
Query: 427 TSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
+ CG+P +V PEV+ YD K D W+ G+++F L+
Sbjct: 167 L-----LHTTCGTPAYVAPEVI--------------NRKGYDGTKADIWSCGVVLFVLLA 207
Query: 487 PFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRV 546
+ F ++ + + Y + K F+ P + + E R+
Sbjct: 208 GYLPFHDS--------NLMEMYRKIGK--ADFKAPSWF---------------APEVRRL 242
Query: 547 CLRLLDPDASTRYTIDDLFNDPWMAK 572
++LDP+ TR TI + W K
Sbjct: 243 LCKMLDPNPETRITIARIRESSWFRK 268
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 79.0 bits (193), Expect = 3e-14
Identities = 93/398 (23%), Positives = 159/398 (39%), Gaps = 59/398 (14%)
Query: 245 MQQPSVMLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFY 304
M++ L FA + GR LG+G +V I + V A+K KD+
Sbjct: 1 MEEEQQQLRVLFAKYEMGR-LLGKGTFGKVYYGKEITTGESV-AIKIIN--KDQVKREGM 56
Query: 305 HRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWA 364
I + ++ H NI++ +M T K F+M+ + G
Sbjct: 57 MEQIKREISIMRLVRHPNIVELKEVMAT-------KTKIFFIMEYVKGGELFSKIVKGKL 109
Query: 365 TKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPE 424
+ K+ F+Q+ + HS G++HRD+K EN+LV + G LK++DFG+S PE
Sbjct: 110 KEDSARKY--FQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSAL----PE 163
Query: 425 DPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
+ + + CG+P +V PEV+ YD K D W+ GI+++ L
Sbjct: 164 QILQDGL-LHTQCGTPAYVAPEVL--------------RKKGYDGAKGDIWSCGIILYVL 208
Query: 485 VCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEAS 544
+ F F +D++ + Y ++ ++ P F S E+
Sbjct: 209 LAGFLPF----QDENLMKMYRKIFKSEFEYPPWF---------------------SPESK 243
Query: 545 RVCLRLLDPDASTRYTIDDLFNDPWMAKIESCFXXXXXXPIKVPELRKATTXXXXXXXXX 604
R+ +LL D + R +I + PW K + +++ + T
Sbjct: 244 RLISKLLVVDPNKRISIPAIMRTPWFRKNINSPIEFKIDELEIQNVEDETPTTTATTATT 303
Query: 605 XSTGSS--FNEENSGLSHSTNPFLESNLKSPKIKSKSM 640
+T S F +S ++ F S+L K K +SM
Sbjct: 304 TTTPVSPKFFNAFEFISSMSSGFDLSSLFESKRKLRSM 341
>SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 513
Score = 78.6 bits (192), Expect = 4e-14
Identities = 76/309 (24%), Positives = 130/309 (41%), Gaps = 48/309 (15%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRC-ITEFMIAKKVSNHVNII 324
+GEG SS + ++ K +Y K F+ D + Y R I E+ A + H NII
Sbjct: 247 IGEGASSFIRVIND-RNKLPIYVAKVFRPPLDTSLLRRYVRYFIAEYTFASTL-RHPNII 304
Query: 325 KTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRH 384
K I+ + + +++ D+F + T + D+ F Q+ G+ +
Sbjct: 305 KVLDIIYK-------RHTILQIIEYVPYDLFTFITKGHCSALKADQM---FFQLLDGVAY 354
Query: 385 MHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVP 444
MHSLGIAHRDIKL+N+++ + +K+ DFG + + P + T+ + G GS P+V
Sbjct: 355 MHSLGIAHRDIKLDNIMLDENLNVKIIDFG-TAFVFHYPFESTT--LMSDGVVGSKPYVA 411
Query: 445 PEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHY 504
PEV+ YDP +D W+ I+ + + H D ++ Y
Sbjct: 412 PEVL--------------TQKPYDPSAVDVWSCAIVYCCIALKRFPWKVPHTSDKRFNLY 457
Query: 505 IAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDL 564
+ R+ P + L + + +LD D +TR +I
Sbjct: 458 V-----------------TQRNDPNTKSQLIESL-PMNSRDTIYHMLDIDFNTRCSISGA 499
Query: 565 FNDPWMAKI 573
+ WM ++
Sbjct: 500 RSTTWMQQV 508
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 78.2 bits (191), Expect = 5e-14
Identities = 48/172 (27%), Positives = 83/172 (47%), Gaps = 34/172 (19%)
Query: 316 KVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTL--SGWATKPLDEKWC 373
KV +H +I+K++ IM+ ++ +++ + Y TL G + + KW
Sbjct: 68 KVIDHPHIVKSYEIMRVDNM--------LYIVSEYCSSGELYETLIEKGRVAENVARKW- 118
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKI 433
F + A + ++HS GI HRD+K EN+L+ +K+ DFG S + D +
Sbjct: 119 -FSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQTGDQ--------LL 169
Query: 434 RGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+CGSPP+ PE+++ YD K D W++G+L++ LV
Sbjct: 170 NTWCGSPPYAAPELLL--------------GNSYDGMKADIWSMGVLLYILV 207
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 78.2 bits (191), Expect = 5e-14
Identities = 66/250 (26%), Positives = 106/250 (42%), Gaps = 53/250 (21%)
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIA 379
H +I++ F ++ T K F+M+ G + L ++ F+Q+
Sbjct: 79 HPSIVRLFEVLAT-------KSKIFFVMEFAKGGELFAKVSKGRFCEDLSRRY--FQQLI 129
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ + HS GI HRD+K EN+L+ + LK++DFG+S + D P + CG+
Sbjct: 130 SAVGYCHSRGIFHRDLKPENLLLDEKLDLKISDFGLS--ALTDQIRPDG---LLHTLCGT 184
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDS 499
P +V PEV+ YD K+D W+ GI++F L
Sbjct: 185 PAYVAPEVL--------------AKKGYDGAKIDIWSCGIILFVL--------------- 215
Query: 500 KYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRY 559
A Y FN H+ +Y+ K S + R+ RLLD + TR
Sbjct: 216 -----NAGYLPFNDHNLMVMYRKIYKG-----EFRIPKWTSPDLRRLLTRLLDTNPQTRI 265
Query: 560 TIDDLFNDPW 569
TI+++ +DPW
Sbjct: 266 TIEEIIHDPW 275
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 77.8 bits (190), Expect = 6e-14
Identities = 73/310 (23%), Positives = 134/310 (42%), Gaps = 64/310 (20%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALK--RFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
K LG G ++V + + A+K + K KD H E + +++ H
Sbjct: 32 KLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKR----EISVMRRL-RHP 86
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
+I+ ++ T K F+M+ S T+ L K+ F+Q+
Sbjct: 87 HIVLLSEVLAT-------KTKIYFVMELAKGGELFSRVTSNRFTESLSRKY--FRQLISA 137
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+R+ H+ G+ HRD+K EN+L+ + LK++DFG+S +K+ P + CG+P
Sbjct: 138 VRYCHARGVFHRDLKPENLLLDENRDLKVSDFGLS--AMKEQIHPDG---MLHTLCGTPA 192
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+V PE+++ YD K D W+ G+++F L + F +
Sbjct: 193 YVAPELLL--------------KKGYDGSKADIWSCGVVLFLLNAGYLPFRD-------- 230
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEH--PEFSKLGSVEASRVCLRLLDPDASTRY 559
P+ G+YR A++ P+++ S + ++ RLL+P+ R
Sbjct: 231 --------------PNIM--GLYRKIHKAQYKLPDWT---SSDLRKLLRRLLEPNPELRI 271
Query: 560 TIDDLFNDPW 569
T++++ DPW
Sbjct: 272 TVEEILKDPW 281
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 77.4 bits (189), Expect = 8e-14
Identities = 65/266 (24%), Positives = 104/266 (38%), Gaps = 51/266 (19%)
Query: 306 RCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWAT 365
R +E + K + H NII + + P W +++ + Q + +
Sbjct: 57 RMASEIQLHKLCNGHKNIIHFYNTAENPQ--------WRWVVLEFAQGGDLFDKIEPDVG 108
Query: 366 KPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGI-STYGIKDPE 424
D F Q+ GI MHS G+AHRD+K EN+L+ G LK++DFG S + K
Sbjct: 109 IDEDVAQFYFAQLMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKS 168
Query: 425 DPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
+ + GSPP+ PE+ YD K+D W+ GI++F L
Sbjct: 169 RLLNSPV------GSPPYAAPEI----------------TQQYDGSKVDVWSCGIILFAL 206
Query: 485 VCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEAS 544
+ + EA + Y Y E+ + H + PG Y
Sbjct: 207 LLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAY-------------------- 246
Query: 545 RVCLRLLDPDASTRYTIDDLFNDPWM 570
+ +L D RY++ + PW+
Sbjct: 247 SIITGMLRSDPFKRYSVKHVVQHPWL 272
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 77.0 bits (188), Expect = 1e-13
Identities = 74/311 (23%), Positives = 126/311 (39%), Gaps = 60/311 (19%)
Query: 264 KTLGEGGSSQVMTVHSIYR--KKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
K LG G ++V +I K + + + K+ K H E I ++V H
Sbjct: 78 KLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKR----EISILRRV-RHP 132
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
I+ F +M T K F+M+ T G + ++ F+Q+
Sbjct: 133 YIVHLFEVMAT-------KSKIYFVMEYVGGGELFNTVAKGRLPEETARRY--FQQLISS 183
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ H G+ HRD+K EN+L+ + G LK++DFG+S + +D +CG+P
Sbjct: 184 VSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHT-----FCGTPA 238
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
++ PEV+ YD K D W+ G+++F L+ F +
Sbjct: 239 YIAPEVL--------------TRKGYDAAKADVWSCGVILFVLMAGHIPFYD-------- 276
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
++ + Y++ K FR P + S + R+ RLLD + TR TI
Sbjct: 277 KNIMVMYKKIYK--GEFRCPRWFSS---------------DLVRLLTRLLDTNPDTRITI 319
Query: 562 DDLFNDPWMAK 572
++ + W K
Sbjct: 320 PEIMKNRWFKK 330
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 76.6 bits (187), Expect = 1e-13
Identities = 77/326 (23%), Positives = 134/326 (40%), Gaps = 61/326 (18%)
Query: 247 QPSVMLTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHR 306
+PSV LT+ + + LG+G ++V S + + V A+K KD+ +
Sbjct: 4 KPSV-LTERYEVG----RLLGQGTFAKVYFGRSNHTNESV-AIKMID--KDKVMRVGLSQ 55
Query: 307 CITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATK 366
I + +++ H N+++ + +M T K F+++ C G +
Sbjct: 56 QIKREISVMRIAKHPNVVELYEVMAT-------KSRIYFVIEYCKGGELFNKVAKGKLKE 108
Query: 367 PLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDP 426
D W F Q+ + HS G+ HRDIK EN+L+ D LK++DFG+S +D
Sbjct: 109 --DVAWKYFYQLISAVDFCHSRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDG 166
Query: 427 TSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
+ CG+P +V PEV+ Y+ K D W+ G+++F L+
Sbjct: 167 L-----LHTTCGTPAYVAPEVI--------------NRKGYEGTKADIWSCGVVLFVLLA 207
Query: 487 PFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRV 546
+ F + + + Y + K F+ P + + E R+
Sbjct: 208 GYLPFHDT--------NLMEMYRKIGK--ADFKCPSWF---------------APEVKRL 242
Query: 547 CLRLLDPDASTRYTIDDLFNDPWMAK 572
++LDP+ TR TI + W K
Sbjct: 243 LCKMLDPNHETRITIAKIKESSWFRK 268
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 76.3 bits (186), Expect = 2e-13
Identities = 55/198 (27%), Positives = 90/198 (44%), Gaps = 44/198 (22%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+Q+ I + HS G+ HRD+K EN+L+ + G LK++DFG+S +D +
Sbjct: 115 FQQLIGAIDYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGL-----LH 169
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
CG+P +V PEV+ YD K D W+ G++++ L+ F F E
Sbjct: 170 TTCGTPAYVAPEVI--------------GKKGYDGAKADVWSCGVVLYVLLAGFLPFHE- 214
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
++ + Y + K F+ P + PE KL S R+LDP+
Sbjct: 215 -------QNLVEMYRKITK--GEFKCPNWF-------PPEVKKLLS--------RILDPN 250
Query: 555 ASTRYTIDDLFNDPWMAK 572
++R I+ + + W K
Sbjct: 251 PNSRIKIEKIMENSWFQK 268
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 76.3 bits (186), Expect = 2e-13
Identities = 60/225 (26%), Positives = 103/225 (45%), Gaps = 38/225 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G + V +I K +V A+K K + + ++ E I K + H +I
Sbjct: 45 KTIGKGNFAVVKLATNIVTKTKV-AIKIID--KTCLNEEYLNKTFREIAILKSL-RHPHI 100
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQIARG 381
+ + +M++ S+ +L+ + ++F + +G +P E F Q+
Sbjct: 101 TRLYEVMESQSM--------IYLVTEYAPNGEIFDHLVANGRMKEP--EAARVFTQLVSA 150
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ + H G+ HRD+K ENVL+ +KL DFG S + E ++ +CGSPP
Sbjct: 151 VHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFSNH--------YEEGATLKTWCGSPP 202
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
+ PEV YD K D W+LG++++ LVC
Sbjct: 203 YAAPEVF--------------QGLEYDGPKSDIWSLGVVLYALVC 233
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 75.9 bits (185), Expect = 2e-13
Identities = 74/312 (23%), Positives = 130/312 (40%), Gaps = 67/312 (21%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+TLGEG S++V + +A+K + CIT ++ ++ +
Sbjct: 15 RTLGEGNSAKVKFAIDTLTGES-FAIKIIE-----------KSCITRLNVSFQIKREIRT 62
Query: 324 IKTFYIMKTPSVSNGPK----RSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQ 377
+K ++K P++ + ++ +++ +CV D+F G ++ K F+Q
Sbjct: 63 LK---VLKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKM--FQQ 117
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
+ G+ + H+ G+ HRD+KLENVL+ G +K+TDFG+S ED + C
Sbjct: 118 LIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGL-----LHTTC 172
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GSP +V PEV+ YD D W+ G++++ ++ F +A
Sbjct: 173 GSPNYVAPEVL--------------ANEGYDGAASDIWSCGVILYVILTGCLPFDDA--- 215
Query: 498 DSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAST 557
+ + K P P + LG A + R+LDP+ T
Sbjct: 216 -----NLAVICRKIFKGDPPI--------------PRWISLG---AKTMIKRMLDPNPVT 253
Query: 558 RYTIDDLFNDPW 569
R TI + W
Sbjct: 254 RVTIAGIKAHDW 265
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 75.9 bits (185), Expect = 2e-13
Identities = 78/308 (25%), Positives = 125/308 (40%), Gaps = 57/308 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K +G G ++V S K+V A+K K + P + + + + A K +H N+
Sbjct: 72 KVIGTGNYAKVKIGFSEEYGKRV-AVKIIS--KVKAPSEYTQKFLPREIEAVKGLHHENL 128
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQD--MFHYTTLSGWATKPLDEKWCCFKQIARG 381
I TFY S+ + +L+ Q ++ + Y + +P + FKQ+
Sbjct: 129 I-TFY----QSIETSHR---VYLIMQLAENGTLLDYVRERKFLDEP--QSRTLFKQLVSA 178
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ ++HS G+ HRDIK EN+L+ + LKL DFG + KD ++ I + +CGS
Sbjct: 179 VEYIHSKGVVHRDIKCENLLLDENWNLKLIDFG---FARKDTRTSDNQVILSKTFCGSYA 235
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+ PE++ YDPF D WA G+ VC +F D S
Sbjct: 236 YASPEIL--------------KGVAYDPFMSDIWACGV-----VCYAMVFGRLPYDGSNV 276
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
+ + V+ P A S E + + +L P RY I
Sbjct: 277 HILL----------KRINQSLVFPKSPSA---------SSECKHMIMHILAP-VKIRYNI 316
Query: 562 DDLFNDPW 569
+ DPW
Sbjct: 317 PQVKEDPW 324
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 74.7 bits (182), Expect = 5e-13
Identities = 67/250 (26%), Positives = 114/250 (44%), Gaps = 45/250 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+ +G G ++V+ V + R +++YA+K K T D TE + + SNH +
Sbjct: 265 RVIGRGSYAKVLMVE-LRRTRRIYAMKVIKKAL-VTDDEDIDWVQTEKHVFETASNHPFL 322
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQD---MFHYTTLSGWATKPLDEKWCCF--KQI 378
+ +TPS F + + V+ M+H + L E+ F +I
Sbjct: 323 VGLHSCFQTPSR--------LFFVIEFVRGGDLMYHMQR-----QRRLPEEHARFYAAEI 369
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCG 438
+ + +H GI +RD+KL+NVL+ G +KLTD+G+ GI+ P D TS +CG
Sbjct: 370 SLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIR-PGDTTST------FCG 422
Query: 439 SPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PFALFAEAH 495
+P ++ PE++ Y F +D WALG+L++ ++ PF L +
Sbjct: 423 TPNYIAPEIL--------------RGEDYG-FSVDWWALGVLLYEMLAGRSPFDLAGASE 467
Query: 496 KDDSKYRHYI 505
D Y+
Sbjct: 468 NPDQNTEDYL 477
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 74.3 bits (181), Expect = 7e-13
Identities = 58/222 (26%), Positives = 99/222 (44%), Gaps = 34/222 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+T+G+G S++V I ++V A+K K + + E I K + NH NI
Sbjct: 63 RTIGKGNSAKVKLARHILTGREV-AIKIID--KTQLNPSSLQKLFREVRIMKGL-NHPNI 118
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K F +++T K + + ++F Y G + E F+QI +
Sbjct: 119 VKLFEVIETE------KTLYLVMEYASAGEVFDYLVSHGRMKEK--EARAKFRQIVSAVH 170
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
+ H I HRD+K EN+L+ +K+ DFG S + + K+ +CGSPP+
Sbjct: 171 YCHQKNIVHRDLKAENLLLDAEANIKIADFGFS--------NEFTLGSKLDTFCGSPPYA 222
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE+ YD ++D W+LG++++ LV
Sbjct: 223 APELF--------------QGKKYDGPEVDIWSLGVILYTLV 250
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 73.9 bits (180), Expect = 9e-13
Identities = 66/252 (26%), Positives = 115/252 (45%), Gaps = 49/252 (19%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFK--LFKDETPDHFYHRCITEFMIAKKVSNHV 321
+ +G G ++V+ V + + ++YA+K K L D+ + TE + ++ SNH
Sbjct: 249 RVIGRGSYAKVLLVR-LKKTDRIYAMKVVKKELVNDDEDIDWVQ---TEKHVFEQASNHP 304
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQD---MFHYTTLSGWATKPLDEKWCCF--K 376
++ +T S F + + V MFH + L E+ F
Sbjct: 305 FLVGLHSCFQT--------ESRLFFVIEYVNGGDLMFHMQR-----QRKLPEEHARFYSA 351
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+I+ + ++H GI +RD+KL+NVL+ G +KLTD+G+ G++ P D TS +
Sbjct: 352 EISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLR-PGDTTST------F 404
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PFALFAE 493
CG+P ++ PE++ Y F +D WALG+LMF ++ PF +
Sbjct: 405 CGTPNYIAPEIL--------------RGEDYG-FSVDWWALGVLMFEMMAGRSPFDIVGS 449
Query: 494 AHKDDSKYRHYI 505
+ D Y+
Sbjct: 450 SDNPDQNTEDYL 461
>CE20636 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 687
Score = 73.9 bits (180), Expect = 9e-13
Identities = 57/238 (23%), Positives = 105/238 (43%), Gaps = 30/238 (12%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVS--NHVNI 323
LG+G +V+ + + A+K + E + E+++ K++S H N+
Sbjct: 337 LGKGTFGKVLLIELESLPGEAVAMKEIEA-SGEHVEQITLNVKKEYILTKRLSAPGHENV 395
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I+ I P FL+ + + +S + FKQ+ G+R
Sbjct: 396 IRFLSIRTMPE--------HYFLIMEYADGGDLFDKISSEYRLTSSQAHGYFKQLIAGLR 447
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
++HS G+ HRDIK EN+++T G LK+TDFG+ T I E+ + CG+P +
Sbjct: 448 YIHSKGVTHRDIKPENLMLTKAGVLKITDFGLGTLHIIKGEESLMDT-----RCGTPQYA 502
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
PEV++ Y +D W+ G+++ N++ + + +A ++Y
Sbjct: 503 APEVLV--------------GNQYRGPPVDIWSAGVVLINMLTGHSPWKKACNFKTQY 546
Score = 64.3 bits (155), Expect = 7e-10
Identities = 72/313 (23%), Positives = 116/313 (37%), Gaps = 59/313 (18%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAK---KVSNHVN 322
L EG QV S A+K+ + F TEF I K K+ H N
Sbjct: 27 LSEGTYGQVSLYESSKNPDVKIAVKQISTAGQS--ERFVEHIKTEFAIHKGLSKIGGHRN 84
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
+I + K L+++ + L + + C FKQ+ G+
Sbjct: 85 VISMMEMRKGSDCYT--------LLKEYADGGDLFKKLETEGEQYSENAQCFFKQLISGL 136
Query: 383 RHMHSLGIAHRDIKLENVLVTDY------GALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+ +H I HRDIKLEN+L+ LK+ DFG++T + D E + +
Sbjct: 137 KFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVD-----GEELMLVDN 191
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHK 496
CGSPP+ PEV + D W+ G+++ ++ + AH+
Sbjct: 192 CGSPPYAAPEV--------------YSKQGHRGPPTDVWSSGVILMAMLTAGLPWDCAHR 237
Query: 497 DDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAS 556
D Y +I FR ++ S A + ++L + S
Sbjct: 238 KDVDYAAWI---------DKKFRTDNLWND------------ISDRALALLRKILCVNVS 276
Query: 557 TRYTIDDLFNDPW 569
R +I+ + DPW
Sbjct: 277 ERVSIEQIEADPW 289
>YKL168c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 734
Score = 73.6 bits (179), Expect = 1e-12
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 40/240 (16%)
Query: 287 YALKRFKLFKDETPDHFYHRCITEFMIAKKVSNH--------VNIIKTFYIMKTPSVSNG 338
YA+K K D + F + +EF+I +S++ NI+ F I++ S
Sbjct: 462 YAVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSS---- 517
Query: 339 PKRSWAFLMQQCVQDMFHYTTLSGWATK----PLDEKWCCFKQIARGIRHMHSLGIAHRD 394
S+ +M+ C + + K PL+ C KQ+ G++ MH GIAH D
Sbjct: 518 ---SFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEAD-CFMKQLLHGVKFMHDHGIAHCD 573
Query: 395 IKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKI-RGYCGSPPHVPPEVMILSXX 453
+K EN+L +G LK+ DFG S+ + R+ +G GS P+V PE +
Sbjct: 574 LKPENILFYPHGLLKICDFGTSSVF----QTAWERRVHAQKGIIGSEPYVAPEEFV---- 625
Query: 454 XXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNK 513
YDP +D W+ G++ ++ L+ A ++ K Y FY++ +
Sbjct: 626 ---------DGEYYDPRLIDCWSCGVVYITMILGHYLWKVASRE--KDMSYDEFYKEMQR 674
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 73.6 bits (179), Expect = 1e-12
Identities = 62/225 (27%), Positives = 100/225 (43%), Gaps = 40/225 (17%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V I K+V A+K K + + E I K V NH NI
Sbjct: 24 KTIGKGNFAKVKLARHILTGKEV-AVKIID--KTQLNSSSLQKLFREVRIMK-VLNHPNI 79
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K F +++T K + + ++F Y G + E F+QI ++
Sbjct: 80 VKLFEVIETE------KTLYLVMEYASGGEVFDYLVAHGRMKEK--EARAKFRQIVSAVQ 131
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS---TYGIKDPEDPTSERIKIRGYCGSP 440
+ H I HRD+K EN+L+ +K+ DFG S T+G K+ +CGSP
Sbjct: 132 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFG-----------NKLDTFCGSP 180
Query: 441 PHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
P+ PE+ YD ++D W+LG++++ LV
Sbjct: 181 PYAAPELF--------------QGKKYDGPEVDVWSLGVILYTLV 211
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 73.6 bits (179), Expect = 1e-12
Identities = 62/225 (27%), Positives = 100/225 (43%), Gaps = 40/225 (17%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V I K+V A+K K + + E I K V NH NI
Sbjct: 24 KTIGKGNFAKVKLARHILTGKEV-AVKIID--KTQLNSSSLQKLFREVRIMK-VLNHPNI 79
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K F +++T K + + ++F Y G + E F+QI ++
Sbjct: 80 VKLFEVIETE------KTLYLVMEYASGGEVFDYLVAHGRMKEK--EARAKFRQIVSAVQ 131
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS---TYGIKDPEDPTSERIKIRGYCGSP 440
+ H I HRD+K EN+L+ +K+ DFG S T+G K+ +CGSP
Sbjct: 132 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFG-----------NKLDTFCGSP 180
Query: 441 PHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
P+ PE+ YD ++D W+LG++++ LV
Sbjct: 181 PYAAPELF--------------QGKKYDGPEVDVWSLGVILYTLV 211
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 73.6 bits (179), Expect = 1e-12
Identities = 62/225 (27%), Positives = 100/225 (43%), Gaps = 40/225 (17%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V I K+V A+K K + + E I K V NH NI
Sbjct: 57 KTIGKGNFAKVKLARHILTGKEV-AVKIID--KTQLNSSSLQKLFREVRIMK-VLNHPNI 112
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K F +++T K + + ++F Y G + E F+QI ++
Sbjct: 113 VKLFEVIETE------KTLYLVMEYASGGEVFDYLVAHGRMKEK--EARAKFRQIVSAVQ 164
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS---TYGIKDPEDPTSERIKIRGYCGSP 440
+ H I HRD+K EN+L+ +K+ DFG S T+G K+ +CGSP
Sbjct: 165 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFG-----------NKLDTFCGSP 213
Query: 441 PHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
P+ PE+ YD ++D W+LG++++ LV
Sbjct: 214 PYAAPELF--------------QGKKYDGPEVDVWSLGVILYTLV 244
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 73.2 bits (178), Expect = 2e-12
Identities = 65/262 (24%), Positives = 110/262 (41%), Gaps = 55/262 (20%)
Query: 316 KVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCC 374
++ H N+++ +M T K+ F+M+ ++F G + L K+
Sbjct: 69 RLLRHPNVVELREVMAT-------KKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKY-- 119
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTY----GIKDPEDPTSER 430
F+Q+ + HS G+ HRDIK EN+L+ G LK+TDFG+S G+ + +
Sbjct: 120 FQQLISAVDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDL 179
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFAL 490
+ R CG+P +V PEV+ YD D W+ GI+++ L+ F
Sbjct: 180 LHTR--CGTPAYVAPEVL--------------RNKGYDGAMADIWSCGIVLYALLAGFLP 223
Query: 491 FAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRL 550
F D++ Y ++ + P F S+E+ + RL
Sbjct: 224 FI----DENVMTLYTKIFKAECEFPPWF---------------------SLESKELLSRL 258
Query: 551 LDPDASTRYTIDDLFNDPWMAK 572
L PD R ++ ++ PW K
Sbjct: 259 LVPDPEQRISMSEIKMIPWFRK 280
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 72.8 bits (177), Expect = 2e-12
Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 36/223 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V + +V A+K K + E I K++ +H NI
Sbjct: 126 KTIGKGNFAKVKLAKHVITGHEV-AIKIID--KTALNPSSLQKLFREVKIMKQL-DHPNI 181
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K + +M+T + L ++F Y G + E F+QI ++
Sbjct: 182 VKLYQVMETEQTL------YLVLEYASGGEVFDYLVAHGRMKEK--EARAKFRQIVSAVQ 233
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS-TYGIKDPEDPTSERIKIRGYCGSPPH 442
++HS I HRD+K EN+L+ +K+ DFG S T+ + + K+ +CGSPP+
Sbjct: 234 YLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGN---------KLDTFCGSPPY 284
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE+ YD ++D W+LG++++ LV
Sbjct: 285 AAPELF--------------SGKKYDGPEVDVWSLGVILYTLV 313
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 72.8 bits (177), Expect = 2e-12
Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 36/223 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V + +V A+K K + E I K++ +H NI
Sbjct: 174 KTIGKGNFAKVKLAKHVITGHEV-AIKIID--KTALNPSSLQKLFREVKIMKQL-DHPNI 229
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K + +M+T + L ++F Y G + E F+QI ++
Sbjct: 230 VKLYQVMETEQTL------YLVLEYASGGEVFDYLVAHGRMKEK--EARAKFRQIVSAVQ 281
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS-TYGIKDPEDPTSERIKIRGYCGSPPH 442
++HS I HRD+K EN+L+ +K+ DFG S T+ + + K+ +CGSPP+
Sbjct: 282 YLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGN---------KLDTFCGSPPY 332
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE+ YD ++D W+LG++++ LV
Sbjct: 333 AAPELF--------------SGKKYDGPEVDVWSLGVILYTLV 361
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 72.4 bits (176), Expect = 3e-12
Identities = 67/252 (26%), Positives = 106/252 (41%), Gaps = 50/252 (19%)
Query: 254 DNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETP--DHFYHRCITEF 311
DNF F + LG+G +VM + R K+ L K+ K + D +TE
Sbjct: 352 DNFEFI----RVLGKGSFGKVM----LARVKETGDLYAVKVLKKDVILLDDDVECTMTEK 403
Query: 312 MIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQD---MFHYTTLSGWATKPL 368
I NH + + F +TP F + + V MFH ++
Sbjct: 404 RILSLARNHPFLTQLFCCFQTPDR--------LFFVMEFVNGGDLMFHIQK-----SRRF 450
Query: 369 DEKWCCF--KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDP 426
DE F +I + +H GI +RD+KL+NVL+ G KL DFG+ GI
Sbjct: 451 DEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI------ 504
Query: 427 TSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
+ +CG+P ++ PE++ Y P +D WA+G+L++ ++C
Sbjct: 505 -CNGVTTATFCGTPDYIAPEIL--------------QEMLYGP-AVDWWAMGVLLYEMLC 548
Query: 487 PFALFAEAHKDD 498
A F ++DD
Sbjct: 549 GHAPFEAENEDD 560
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 72.4 bits (176), Expect = 3e-12
Identities = 68/263 (25%), Positives = 109/263 (40%), Gaps = 49/263 (18%)
Query: 264 KTLGEGGSSQV-MTVHSIYRKK-QVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
KTLG+G + V + VH I +K + + R KL + + KV +
Sbjct: 55 KTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSES---------------VLMKVEREI 99
Query: 322 NIIKTF---YIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQI 378
I+K +++K V K + L ++F Y G T K+ F+QI
Sbjct: 100 AILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKF--FRQI 157
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCG 438
+ HS I HRD+K EN+L+ + +++ DFG+++ + D TS CG
Sbjct: 158 VSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS--------CG 209
Query: 439 SPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDD 498
SP + PEV+ YD + D W+ G+++F L+ F DD
Sbjct: 210 SPHYACPEVI--------------KGEKYDGRRADMWSCGVILFALLVGALPF-----DD 250
Query: 499 SKYRHYIAFYEQFNKHSPHFRKP 521
R + ++ H PHF P
Sbjct: 251 DNLRQLLEKVKRGVFHMPHFIPP 273
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 72.4 bits (176), Expect = 3e-12
Identities = 61/234 (26%), Positives = 108/234 (46%), Gaps = 58/234 (24%)
Query: 264 KTLGEGGSSQV-MTVH---------SIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMI 313
KTLG+G ++V + +H + K + + R KL++ E I
Sbjct: 67 KTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYR-------------EVNI 113
Query: 314 AKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEK 371
KK+ NH NI++ ++++ +L+ + V ++F+Y +G + D +
Sbjct: 114 MKKL-NHPNIVRLLQVIESERT--------LYLVMEYVSGGELFNYLVKNG-RMRERDAR 163
Query: 372 WCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERI 431
F+Q+ I + HS I HRD+K EN+L+ LK+ DFG ST +P+ P
Sbjct: 164 -VLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFST--TFEPKAP----- 215
Query: 432 KIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+ +CGSPP+ PE+ Y ++D+W+LG++++ LV
Sbjct: 216 -LETFCGSPPYAAPELF--------------RGKKYSGPEVDSWSLGVVLYTLV 254
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 71.6 bits (174), Expect = 4e-12
Identities = 71/313 (22%), Positives = 124/313 (38%), Gaps = 69/313 (22%)
Query: 264 KTLGEGGSSQVMT-VHSIY-RKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
KTLG+G + V T H I RK + + + KL + + +KV +
Sbjct: 51 KTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSES---------------VLQKVEREI 95
Query: 322 NIIKTF---YIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQI 378
I+K +++ V K + L ++F Y G K+ F+QI
Sbjct: 96 AIMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKF--FRQI 153
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCG 438
+ H+ I HRD+K EN+L+ + +K+ DFG+++ ++ TS CG
Sbjct: 154 ISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETS--------CG 205
Query: 439 SPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDD 498
SP + PEV+ YD K D W+ G++++ L+ F DD
Sbjct: 206 SPHYACPEVI--------------RGEKYDGRKADVWSCGVILYALLVGALPF-----DD 246
Query: 499 SKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTR 558
R+ + ++ H PHF + + +++ D R
Sbjct: 247 DNLRNLLEKVKRGVFHIPHF--------------------VPADVQSLLRAMIEVDPGKR 286
Query: 559 YTIDDLFNDPWMA 571
Y++ D+F PW++
Sbjct: 287 YSLADVFKHPWVS 299
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 71.6 bits (174), Expect = 4e-12
Identities = 52/198 (26%), Positives = 87/198 (43%), Gaps = 44/198 (22%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+Q+ + + HS G++HRD+K EN+L+ + G LK++DFG+S PE + + +
Sbjct: 116 FQQLISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSAL----PEQILQDGL-LH 170
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
CG+P +V PEV+ YD K D W+ G++++ L+ F
Sbjct: 171 TQCGTPAYVAPEVL--------------KKKGYDGAKADIWSCGVVLYVLLAGCLPF--- 213
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
+D++ Y + + P F S EA R+ +LL D
Sbjct: 214 -QDENLMNMYRKIFRADFEFPPWF---------------------SPEARRLISKLLVVD 251
Query: 555 ASTRYTIDDLFNDPWMAK 572
R +I + PW+ K
Sbjct: 252 PDRRISIPAIMRTPWLRK 269
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 71.6 bits (174), Expect = 4e-12
Identities = 58/222 (26%), Positives = 100/222 (44%), Gaps = 34/222 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V + K+V A+K K + + E I K + +H NI
Sbjct: 155 KTIGKGNFAKVKLAKHLPTGKEV-AIKIID--KTQLNPGSLQKLFREVRIMKML-DHPNI 210
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K F +++T K + + ++F Y L G + E F+QI ++
Sbjct: 211 VKLFQVIETE------KTLYLIMEYASGGEVFDYLVLHGRMKEK--EARVKFRQIVSAVQ 262
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
+ H I HRD+K EN+L+ +K+ DFG S + + K+ +CGSPP+
Sbjct: 263 YCHQKRIIHRDLKAENLLLDSELNIKIADFGFS--------NEFTPGSKLDTFCGSPPYA 314
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE+ YD ++D W+LG++++ LV
Sbjct: 315 APELF--------------QGKKYDGPEVDVWSLGVILYTLV 342
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 70.9 bits (172), Expect = 8e-12
Identities = 57/223 (25%), Positives = 100/223 (44%), Gaps = 34/223 (15%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
+KT+G+G ++V + ++V A+K K + + E I K + NH N
Sbjct: 63 QKTIGKGNFAKVKLARHVLTGREV-AVKIID--KTQLNPTSLQKLFREVRIMK-ILNHPN 118
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
I+K F +++T K + + ++F Y G + E F+QI +
Sbjct: 119 IVKLFEVIETE------KTLYLVMEYASGGEVFDYLVAHGRMKEK--EARAKFRQIVSAV 170
Query: 383 RHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
++ H I HRD+K EN+L+ +K+ DFG S + + K+ +CGSPP+
Sbjct: 171 QYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFS--------NEFTVGNKLDTFCGSPPY 222
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE+ YD ++D W+LG++++ LV
Sbjct: 223 AAPELF--------------QGKKYDGPEVDVWSLGVILYTLV 251
>Hs14042966 [T] KOG0583 Serine/threonine protein kinase
Length = 273
Score = 70.9 bits (172), Expect = 8e-12
Identities = 60/223 (26%), Positives = 101/223 (44%), Gaps = 33/223 (14%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+T+GEG S+V S + K A+K + + P F ++ + + + H +I
Sbjct: 16 RTIGEGSYSKVKVATS-KKYKGTVAIK--VVDRRRAPPDFVNKFLPRELSILRGVRHPHI 72
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+ F ++ V NG +M+ D+ +G P + F QIA +R
Sbjct: 73 VHVFEFIE---VCNG---KLYIVMEAAATDLLQAVQRNGRI--PGVQARDLFAQIAGAVR 124
Query: 384 HMHSLGIAHRDIKLENVLVT-DYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
++H + HRD+K ENVL++ D +KLTDFG P+ T+ YCGS +
Sbjct: 125 YLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTT-------YCGSAAY 177
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PEV++ YDP K D W++G++++ +V
Sbjct: 178 ASPEVLL--------------GIPYDPKKYDVWSMGVVLYVMV 206
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 70.9 bits (172), Expect = 8e-12
Identities = 52/198 (26%), Positives = 83/198 (41%), Gaps = 46/198 (23%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F Q+ G+ + HS G+ HRD+K EN+L+ G LK++DFG+S P ++
Sbjct: 113 FHQLIDGVDYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLSAL-------PEQGVTILK 165
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
CG+P +V PEV+ Y+ D W+ G++++ L+ + F E
Sbjct: 166 TTCGTPNYVAPEVL--------------SHKGYNGAVADIWSCGVILYVLMAGYLPFDEM 211
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
Y + +K F P + G A + R+LDP+
Sbjct: 212 DLP--------TLYSKIDK--AEFSCPSYFALG---------------AKSLINRILDPN 246
Query: 555 ASTRYTIDDLFNDPWMAK 572
TR TI ++ D W K
Sbjct: 247 PETRITIAEIRKDEWFLK 264
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 70.9 bits (172), Expect = 8e-12
Identities = 71/284 (25%), Positives = 116/284 (40%), Gaps = 51/284 (17%)
Query: 245 MQQPSVMLTDNFAFADSGR--KTLGEGGSSQV-MTVHSIYRKK-QVYALKRFKLFKDETP 300
MQ+ + + +N F R KTLG+G + V + VH + KK + + R KL +
Sbjct: 1 MQKENNVTAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSES--- 57
Query: 301 DHFYHRCITEFMIAKKVSNHVNIIKTF---YIMKTPSVSNGPKRSWAFLMQQCVQDMFHY 357
+ KV + I+K +++ V K + L ++F Y
Sbjct: 58 ------------VLMKVEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDY 105
Query: 358 TTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST 417
G T K+ F+QI + HS I HRD+K EN+L+ + +K+ DFG+++
Sbjct: 106 LVKKGRLTPKEARKF--FRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMAS 163
Query: 418 YGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWAL 477
P ++ CGSP + PEV+ YD K D W+
Sbjct: 164 L------QPAGSMLETS--CGSPHYACPEVI--------------RGEKYDGRKADVWSC 201
Query: 478 GILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKP 521
G++++ L+ F DD R + ++ H PHF P
Sbjct: 202 GVILYALLVGALPF-----DDDNLRQLLEKVKRGVFHIPHFVPP 240
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 70.1 bits (170), Expect = 1e-11
Identities = 62/242 (25%), Positives = 110/242 (44%), Gaps = 44/242 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYR--KKQVYALKRFKLFKDETPDHFYH--RCITEFMIAKKVSN 319
+TLG G + V ++ K V + + KL D + H + RC+ K+
Sbjct: 24 ETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKL-DDVSKAHLFQEVRCM-------KLVQ 75
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTL-SGWATKPLDEKWCCFKQI 378
H N+++ + ++ T + + + L D++ Y ++ L K+ F+QI
Sbjct: 76 HPNVVRLYEVIDTQT------KLYLVLELGDGGDLYDYIMKHDSGLSEELARKY--FRQI 127
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTD-YGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
R I + H L + HRD+K ENV+ + G +KLTDFG S + K+ +C
Sbjct: 128 LRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQ--------KLETFC 179
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GS + PE+++ YD +D W+LG++++ LVC A F +A+
Sbjct: 180 GSLAYSAPEILL--------------GDSYDAPAVDIWSLGVILYMLVCGQAPFEKANDS 225
Query: 498 DS 499
++
Sbjct: 226 ET 227
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 69.7 bits (169), Expect = 2e-11
Identities = 53/196 (27%), Positives = 83/196 (42%), Gaps = 52/196 (26%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
FKQ+ I+H+H GI HRDIK ENV+V +G +KL DFG + Y P D
Sbjct: 956 FKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDV-------- 1007
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
+ G+ + PEV+ Y D WALG+L++ ++
Sbjct: 1008 -FVGTMDYAAPEVL--------------GGSSYKGKPQDIWALGVLLYTII--------- 1043
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
+K++ Y ++ + F K +EH S E + R+L +
Sbjct: 1044 YKENPYYN-----IDEILEGELRFDK---------SEHV------SEECISLIKRILTRE 1083
Query: 555 ASTRYTIDDLFNDPWM 570
R TID+++ D W+
Sbjct: 1084 VDKRPTIDEIYEDKWL 1099
>YJL165c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 855
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/220 (27%), Positives = 93/220 (42%), Gaps = 36/220 (16%)
Query: 361 SGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGI 420
SG PL+ C KQ+ G+++MH GIAH D+K EN+L G LK+ DFG S+
Sbjct: 656 SGSPLHPLEAD-CFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVF- 713
Query: 421 KDPEDPTSERIKIR-GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGI 479
+ + + + G GS P+V PE I YDP +D W+ GI
Sbjct: 714 ---QTAWEKHVHFQSGAMGSEPYVAPEEFI-------------RDAEYDPRLVDCWSCGI 757
Query: 480 LMFNLVCPFALFAEA-HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEH--PEFS 536
+ +V L+ A + DS ++ +++ + G + H E +
Sbjct: 758 VYCTMVMGQYLWKIAIPEKDSLFKSFLS----------EIKDDGQFYLFEELRHVSSELN 807
Query: 537 KLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMAKIESC 576
+L + R D + R TI+ L WM K + C
Sbjct: 808 RLRKI----ALYRTFQVDPTKRITIEQLLQSSWMRKTKCC 843
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 69.7 bits (169), Expect = 2e-11
Identities = 58/222 (26%), Positives = 98/222 (44%), Gaps = 34/222 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V I ++V A+K K + + E I K + NH NI
Sbjct: 60 KTIGKGNFAKVKLARHILTGREV-AIKIID--KTQLNPTSLQKLFREVRIMK-ILNHPNI 115
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
+K F +++T K + + +F Y G + E F+QI ++
Sbjct: 116 VKLFEVIETQ------KTLYLIMEYASGGKVFDYLVAHGRMKEK--EARSKFRQIVSAVQ 167
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
+ H I HRD+K EN+L+ +K+ DFG S + + K+ +CGSPP+
Sbjct: 168 YCHQKRIVHRDLKAENLLLDADMNIKIADFGFS--------NEFTVGGKLDTFCGSPPYA 219
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE+ YD ++D W+LG++++ LV
Sbjct: 220 APELF--------------QGKKYDGPEVDVWSLGVILYTLV 247
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 69.7 bits (169), Expect = 2e-11
Identities = 56/195 (28%), Positives = 84/195 (42%), Gaps = 44/195 (22%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+Q+ GI + HS G+ HRD+KLENVL+ G +K+TDFG+S +D +
Sbjct: 124 FQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGL-----LH 178
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
CGSP +V PEV+ YD D W+ G++++ ++ F
Sbjct: 179 TTCGSPNYVAPEVL--------------ANRGYDGAASDIWSCGVILYVILTGCLPF--- 221
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
DD R+ Y++ K P P PGA + R+LDP+
Sbjct: 222 --DD---RNLAVLYQKICKGDP----PIPRWLSPGAR-------------TMIKRMLDPN 259
Query: 555 ASTRYTIDDLFNDPW 569
TR T+ + W
Sbjct: 260 PVTRITVVGIKASEW 274
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/224 (26%), Positives = 101/224 (44%), Gaps = 36/224 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQ--VYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
+ LGEG +V V I K +YA+K K + D R E I V H
Sbjct: 203 RVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRV--RSTNERKILADVG-HA 259
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
I++ Y +TP +L+ ++ +T LS ++ ++A
Sbjct: 260 FIVRLHYAFQTPGK--------LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 311
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ H+H+LGI +RD+K EN+L+ ++G + LTDFG+S K P D + K +CG+
Sbjct: 312 MNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLS----KQPLDGS----KTYSFCGTVE 363
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++ PE++ +D F D W+ G+LM+ ++
Sbjct: 364 YMAPEIV--------------NRKGHD-FAADWWSFGVLMYEML 392
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 69.3 bits (168), Expect = 2e-11
Identities = 78/317 (24%), Positives = 128/317 (39%), Gaps = 69/317 (21%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDET--PDHFYH--RCITEFMIAKKVSN 319
KTLG G + V ++ ++V A+K K +T H + RC+ K+
Sbjct: 20 KTLGRGHFAVVKLARHVFTGEKV-AVKVIDKTKLDTLATGHLFQEVRCM-------KLVQ 71
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTL-SGWATKPLDEKWCCFKQI 378
H NI++ + ++ T + + + L DMF Y + L +K+ F QI
Sbjct: 72 HPNIVRLYEVIDTQT------KLYLILELGDEGDMFDYIMKHEEGLNEDLPKKY--FAQI 123
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTD-YGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I + H L + HRD+K ENV+ + G +KLTDFG S + TS C
Sbjct: 124 VHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTS--------C 175
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GS + PE+++ YD +D W+LG+++F LVC F EA+
Sbjct: 176 GSLAYSAPEILL--------------GDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDS 221
Query: 498 DSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAST 557
++ Y H K E + R+L D
Sbjct: 222 ETLTMIMDCKYTV----PSHVSK---------------------ECKDLITRMLQRDPKR 256
Query: 558 RYTIDDLFNDPWMAKIE 574
R +++++ N PW+ ++
Sbjct: 257 RASLEEIENHPWLQGVD 273
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 68.9 bits (167), Expect = 3e-11
Identities = 57/224 (25%), Positives = 97/224 (42%), Gaps = 35/224 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRK--KQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
K LG+G +V V I +Q+YA+K K + D + + ++ NH
Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEV---NHP 128
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
I+K Y +T +L+ ++ +T LS ++ ++A
Sbjct: 129 FIVKLHYAFQTEGK--------LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 180
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ H+HSLGI +RD+K EN+L+ + G +KLTDFG+S I + K +CG+
Sbjct: 181 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEK-------KAYSFCGTVE 233
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++ PEV+ D W+ G+LMF ++
Sbjct: 234 YMAPEVVNRRGHTQSA---------------DWWSFGVLMFEML 262
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 68.6 bits (166), Expect = 4e-11
Identities = 60/224 (26%), Positives = 97/224 (42%), Gaps = 35/224 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQ--VYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
K LG+G +V V + R +YA+K K + D R E I V NH
Sbjct: 66 KVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRV--RTKMERDILADV-NHP 122
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
++K Y +T +L+ ++ +T LS ++ ++A G
Sbjct: 123 FVVKLHYAFQTEGK--------LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALG 174
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ H+HSLGI +RD+K EN+L+ + G +KLTDFG+S I + K +CG+
Sbjct: 175 LDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEK-------KAYSFCGTVE 227
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++ PEV+ D W+ G+LMF ++
Sbjct: 228 YMAPEVVNRQGHSHSA---------------DWWSYGVLMFEML 256
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 68.6 bits (166), Expect = 4e-11
Identities = 55/233 (23%), Positives = 110/233 (46%), Gaps = 56/233 (24%)
Query: 264 KTLGEGGSSQV-MTVH---------SIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMI 313
KTLG+G ++V + +H + K Q+ R KL+++ +
Sbjct: 102 KTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYRE--------------VK 147
Query: 314 AKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKW 372
K+ NH NI++ F ++++ +R+ +M+ + ++F + +G + D +
Sbjct: 148 IMKLLNHPNIVRLFQVIES-------ERTLYLVMEYASRGELFDHLVKNG-RMRERDAR- 198
Query: 373 CCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIK 432
F+Q+ I++ HS + HRD+K EN+L+ + +K+ DFG + DP ++
Sbjct: 199 VIFRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFG-----NTFDPNAQ--- 250
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+ +CGSPP+ PE+ + Y ++D W+LG++++ LV
Sbjct: 251 LETFCGSPPYAAPELFM--------------GRKYAGPEVDAWSLGVVLYTLV 289
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 68.2 bits (165), Expect = 5e-11
Identities = 67/242 (27%), Positives = 107/242 (43%), Gaps = 44/242 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDET--PDHFYH--RCITEFMIAKKVSN 319
KTLG G + V ++ ++V A+K K +T H + RC+ K+
Sbjct: 20 KTLGRGHFAVVKLARHVFTGEKV-AVKVIDKTKLDTLATGHLFQEVRCM-------KLVQ 71
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTL-SGWATKPLDEKWCCFKQI 378
H NI++ + ++ T + + + L DMF Y + L +K+ F QI
Sbjct: 72 HPNIVRLYEVIDTQT------KLYLILELGDGGDMFDYIMKHEEGLNEDLAKKY--FAQI 123
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTD-YGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I + H L + HRD+K ENV+ + G +KLTDFG S + TS C
Sbjct: 124 VHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTS--------C 175
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GS + PE+++ YD +D W+LG+++F LVC F EA+
Sbjct: 176 GSLAYSAPEILL--------------GDEYDAPAVDIWSLGVILFMLVCEQPPFQEANDS 221
Query: 498 DS 499
++
Sbjct: 222 ET 223
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 67.8 bits (164), Expect = 6e-11
Identities = 71/308 (23%), Positives = 130/308 (42%), Gaps = 60/308 (19%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+T+G GG ++V I + V K+ T R TE K + H +I
Sbjct: 15 ETIGTGGFAKVKLACHILTGEMV----AIKIMDKNTLGSDLPRIKTEIEALKNL-RHQHI 69
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
+ +++++T + +++ C ++F Y ++ +E F+QI +
Sbjct: 70 CQLYHVLETAN-------KIFMVLEYCPGGELFDYIISQDRLSE--EETRVVFRQIVSAV 120
Query: 383 RHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
++HS G AHRD+K EN+L +Y LKL DFG+ + ++ ++ CGS +
Sbjct: 121 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCA------KPKGNKDYHLQTCCGSLAY 174
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYR 502
PE++ Y + D W++GIL++ L+C F F DD
Sbjct: 175 AAPELI--------------QGKSYLGSEADVWSMGILLYVLMCGFLPF-----DDD--- 212
Query: 503 HYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTID 562
+ +A Y++ + G Y + K S + + ++L D R ++
Sbjct: 213 NVMALYKKIMR--------GKY---------DVPKWLSPSSILLLQQMLQVDPKKRISMK 255
Query: 563 DLFNDPWM 570
+L N PW+
Sbjct: 256 NLLNHPWI 263
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 67.4 bits (163), Expect = 8e-11
Identities = 56/203 (27%), Positives = 80/203 (38%), Gaps = 66/203 (32%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
FKQ+ GI+H+H GI HRDIK ENV+V G +K+ DFG + Y P D
Sbjct: 1211 FKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDV-------- 1262
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PFALF 491
+ G+ + PEV+ Y+ D WA+GIL++ +V PF
Sbjct: 1263 -FVGTIDYAAPEVL--------------GGNPYEGQPQDIWAIGILLYTVVFKENPFYNI 1307
Query: 492 AEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRL- 550
E + D K+ + + E S C+ L
Sbjct: 1308 DEILEGDLKFNN------------------------------------AEEVSEDCIELI 1331
Query: 551 ---LDPDASTRYTIDDLFNDPWM 570
L+ R TIDD+ ND W+
Sbjct: 1332 KSILNRCVPKRPTIDDINNDKWL 1354
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 67.0 bits (162), Expect = 1e-10
Identities = 36/111 (32%), Positives = 58/111 (51%), Gaps = 22/111 (19%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+QI + + H G+ HRD+KLEN+L+ D +K+ DFG+S KD ++
Sbjct: 159 FRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDK--------FLQ 210
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+CGSP + PE++ Y ++D+WALG+L++ LV
Sbjct: 211 TFCGSPLYASPEIV--------------NGRPYRGPEVDSWALGVLLYTLV 247
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 67.0 bits (162), Expect = 1e-10
Identities = 57/228 (25%), Positives = 98/228 (42%), Gaps = 43/228 (18%)
Query: 264 KTLGEGGSSQVMTVHSIYRKK------QVYALKRFKLFKDETPDHFYHRCITEFMIAKKV 317
K LG+G +V V RKK Q+YA+K K + D + + ++
Sbjct: 77 KVLGQGSFGKVFLV----RKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEV-- 130
Query: 318 SNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQ 377
NH I+K Y +T +L+ ++ +T LS ++ +
Sbjct: 131 -NHPFIVKLHYAFQTEGK--------LYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAE 181
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
+A + H+H LGI +RD+K EN+L+ + G +KLTDFG+S ++ + K +C
Sbjct: 182 LALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLS-------KESVDQEKKAYSFC 234
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
G+ ++ PEV+ D W+ G+LMF ++
Sbjct: 235 GTVEYMAPEVVNRRGHSQSA---------------DWWSYGVLMFEML 267
>Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 400
Score = 67.0 bits (162), Expect = 1e-10
Identities = 58/202 (28%), Positives = 85/202 (41%), Gaps = 51/202 (25%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTD---YGALKLTDFGISTYGIKDPEDPTSERIK 432
K I I+++HS+ IAHRD+K EN+L T LKLTDFG + T+
Sbjct: 168 KSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFA--------KETTSHNS 219
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFA 492
+ C +P +V PEV+ YD D W+LG++M+ L+C + F
Sbjct: 220 LTTPCYTPYYVAPEVL--------------GPEKYDK-SCDMWSLGVIMYILLCGYPPFY 264
Query: 493 EAH----KDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
H K R + YE N PE+S++ S E +
Sbjct: 265 SNHGLAISPGMKTRIRMGQYEFPN--------------------PEWSEV-SEEVKMLIR 303
Query: 549 RLLDPDASTRYTIDDLFNDPWM 570
LL + + R TI + N PW+
Sbjct: 304 NLLKTEPTQRMTITEFMNHPWI 325
>Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 370
Score = 67.0 bits (162), Expect = 1e-10
Identities = 58/202 (28%), Positives = 85/202 (41%), Gaps = 51/202 (25%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTD---YGALKLTDFGISTYGIKDPEDPTSERIK 432
K I I+++HS+ IAHRD+K EN+L T LKLTDFG + T+
Sbjct: 168 KSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFA--------KETTSHNS 219
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFA 492
+ C +P +V PEV+ YD D W+LG++M+ L+C + F
Sbjct: 220 LTTPCYTPYYVAPEVL--------------GPEKYDK-SCDMWSLGVIMYILLCGYPPFY 264
Query: 493 EAH----KDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
H K R + YE N PE+S++ S E +
Sbjct: 265 SNHGLAISPGMKTRIRMGQYEFPN--------------------PEWSEV-SEEVKMLIR 303
Query: 549 RLLDPDASTRYTIDDLFNDPWM 570
LL + + R TI + N PW+
Sbjct: 304 NLLKTEPTQRMTITEFMNHPWI 325
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 67.0 bits (162), Expect = 1e-10
Identities = 61/238 (25%), Positives = 100/238 (41%), Gaps = 35/238 (14%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQ--VYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
K LG+G +V V + + VYA+K K + D R E I +S H
Sbjct: 108 KVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR--QRTKLERNILAHIS-HP 164
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
I+K Y +T +L+ ++ +T LS D+ ++
Sbjct: 165 FIVKLHYAFQTEGK--------LYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLA 216
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ H+HSLGI +RD+K EN+L+ G +K+TDFG+S I + K +CG+
Sbjct: 217 LEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEK-------KTYSFCGTVE 269
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDS 499
++ PEV+ D W+LG+LMF ++ F ++D+
Sbjct: 270 YMAPEVINRRGHSMAA---------------DFWSLGVLMFEMLTGHLPFQGRDRNDT 312
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 67.0 bits (162), Expect = 1e-10
Identities = 61/238 (25%), Positives = 100/238 (41%), Gaps = 35/238 (14%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQ--VYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
K LG+G +V V + + VYA+K K + D R E I +S H
Sbjct: 51 KVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR--QRTKLERNILAHIS-HP 107
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
I+K Y +T +L+ ++ +T LS D+ ++
Sbjct: 108 FIVKLHYAFQTEGK--------LYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLA 159
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ H+HSLGI +RD+K EN+L+ G +K+TDFG+S I + K +CG+
Sbjct: 160 LEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEK-------KTYSFCGTVE 212
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDS 499
++ PEV+ D W+LG+LMF ++ F ++D+
Sbjct: 213 YMAPEVINRRGHSMAA---------------DFWSLGVLMFEMLTGHLPFQGRDRNDT 255
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 67.0 bits (162), Expect = 1e-10
Identities = 64/246 (26%), Positives = 110/246 (44%), Gaps = 53/246 (21%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFK--LFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+G G ++V+ + +Q+YA+K K +F ++ + TE + + SN+ +
Sbjct: 259 IGRGSYAKVVQAEHV-STRQIYAIKIIKKEMFNEDEDIDWVQ---TEKSVFEAASNYPFL 314
Query: 324 IKTFYIMKTPS-----VSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFK-- 376
+ +T S + P F MQQ + L E+ F
Sbjct: 315 VGLHSCFQTESRLFFVIEFVPGGDLMFHMQQ---------------QRKLPEEHARFYSG 359
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+I + +HS GI +RD+KL+NVL+ G +KLTD+G+ IKD D TS +
Sbjct: 360 EIILALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKD-GDLTST------F 412
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PFALFAE 493
CG+P ++ PE++ Y F +D WALG+LMF ++ PF +
Sbjct: 413 CGTPNYIAPEIL--------------RGDEYG-FSVDWWALGVLMFEMMAGRSPFDIVGM 457
Query: 494 AHKDDS 499
+ +++
Sbjct: 458 QNSEEN 463
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 66.6 bits (161), Expect = 1e-10
Identities = 42/174 (24%), Positives = 80/174 (45%), Gaps = 30/174 (17%)
Query: 312 MIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEK 371
++ K+ +H N++ + + +T + +L+ + + + L P E
Sbjct: 78 IVIMKLLSHPNVLSLYDVWET--------NNNLYLILEYAEKGELFNLLVDHGPLPEREA 129
Query: 372 WCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERI 431
CF+QI GI + H+LGI HRD+K EN+L+ + +K+ DFG++ ++
Sbjct: 130 INCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAAL--------QTDAD 181
Query: 432 KIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+ CGSP + PE++ Y+ F D W+ G+++F L+
Sbjct: 182 LLETSCGSPHYAAPEIV--------------SGLPYEGFASDVWSCGVILFALL 221
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 66.6 bits (161), Expect = 1e-10
Identities = 52/184 (28%), Positives = 86/184 (46%), Gaps = 38/184 (20%)
Query: 316 KVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWC 373
K+ H +IIK + ++ TPS F++ + V ++F Y +G LDEK
Sbjct: 71 KLFRHPHIIKLYQVISTPSD--------IFMVMEYVSGGELFDYICKNG----RLDEKES 118
Query: 374 --CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERI 431
F+QI G+ + H + HRD+K ENVL+ + K+ DFG+S + S+
Sbjct: 119 RRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS--------NMMSDGE 170
Query: 432 KIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALF 491
+R CGSP + PEV+ Y ++D W+ G++++ L+C F
Sbjct: 171 FLRTSCGSPNYAAPEVI--------------SGRLYAGPEVDIWSSGVILYALLCGTLPF 216
Query: 492 AEAH 495
+ H
Sbjct: 217 DDDH 220
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 66.2 bits (160), Expect = 2e-10
Identities = 40/138 (28%), Positives = 68/138 (48%), Gaps = 33/138 (23%)
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSE---------RIK 432
I ++HS GI HRD+K +N+L+T G +KLTDFG+S G+ + +E + +
Sbjct: 469 IEYLHSYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQ 528
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV------- 485
+ CG+P ++ PEV++ +D WALGI+++ +
Sbjct: 529 DKQLCGTPEYIAPEVILRRGYGK---------------PVDWWALGIILYEFLVGIVPFF 573
Query: 486 --CPFALFAEAHKDDSKY 501
P ALF++ +D +Y
Sbjct: 574 GETPEALFSKVISEDVEY 591
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 65.9 bits (159), Expect = 2e-10
Identities = 77/311 (24%), Positives = 124/311 (39%), Gaps = 67/311 (21%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+T+G+G + V K +V K D+T +R E I K++ H +I
Sbjct: 145 RTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYR---EVEIMKRLK-HPHI 200
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFK--QIA 379
IK + +M+T ++ +++ + ++F Y G + E FK QI
Sbjct: 201 IKLYQVMET--------KNMIYIVSEYASQGEIFDYIAKYG----RMSESAARFKFWQII 248
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ + H GI HRD+K EN+L+ +K+ DFG S + K E + +CGS
Sbjct: 249 SAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNH-FKPGE-------LLATWCGS 300
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDS 499
PP+ PEV Y ++D W+LG++++ LVC F +
Sbjct: 301 PPYAAPEVF--------------EGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSL 346
Query: 500 KYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRY 559
+ R S FR P S E + R+L + + RY
Sbjct: 347 RDRVL----------SGRFRIPFFMSS---------------ECEHLIRRMLVLEPTRRY 381
Query: 560 TIDDLFNDPWM 570
TID + WM
Sbjct: 382 TIDQIKRHRWM 392
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 65.5 bits (158), Expect = 3e-10
Identities = 57/228 (25%), Positives = 104/228 (45%), Gaps = 38/228 (16%)
Query: 262 GRKTLGEGGSSQVMT-VHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNH 320
G + LGEG ++V +H + +K + K K +T + + + +++ H
Sbjct: 64 GSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDT---YVTKNLRREGQIQQMIRH 120
Query: 321 VNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWC--CFKQI 378
NI + I++T + S+ +M+ C + + K L+E +Q+
Sbjct: 121 PNITQLLDILET-------ENSYYLVMELCPGGNLMHKI---YEKKRLEESEARRYIRQL 170
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST-YGIKDPEDPTSERIKIRGYC 437
+ H+H G+ HRD+K+EN+L+ + +KL DFG+S GI DP S + C
Sbjct: 171 ISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQ------C 224
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
GSP + PE++ Y P K+D W++G+ M+ ++
Sbjct: 225 GSPAYAAPELL--------------ARKKYGP-KIDVWSIGVNMYAML 257
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 65.5 bits (158), Expect = 3e-10
Identities = 65/241 (26%), Positives = 110/241 (44%), Gaps = 51/241 (21%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFK---LFKDETPDHFYHRCITEFMIAKKVSNH 320
+ +G G ++V+ V + + Q+YA+K K + DE D TE + ++ S++
Sbjct: 256 RVIGRGSYAKVLLVR-LKKNDQIYAMKVVKKELVHDDEDIDWVQ----TEKHVFEQASSN 310
Query: 321 VNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQD---MFHYTTLSGWATKPLDEKWCCF-- 375
++ +T S FL+ + V MFH + L E+ F
Sbjct: 311 PFLVGLHSCFQTTSR--------LFLVIEYVNGGDLMFHMQR-----QRKLPEEHARFYA 357
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+I + +H GI +RD+KL+NVL+ G +KLTD+G+ G+ P D TS
Sbjct: 358 AEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGL-GPGDTTST------ 410
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PFALFA 492
+CG+P ++ PE++ Y F +D WALG+LMF ++ PF +
Sbjct: 411 FCGTPNYIAPEIL--------------RGEEYG-FSVDWWALGVLMFEMMAGRSPFDIIT 455
Query: 493 E 493
+
Sbjct: 456 D 456
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 65.5 bits (158), Expect = 3e-10
Identities = 65/241 (26%), Positives = 110/241 (44%), Gaps = 51/241 (21%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFK---LFKDETPDHFYHRCITEFMIAKKVSNH 320
+ +G G ++V+ V + + Q+YA+K K + DE D TE + ++ S++
Sbjct: 256 RVIGRGSYAKVLLVR-LKKNDQIYAMKVVKKELVHDDEDIDWVQ----TEKHVFEQASSN 310
Query: 321 VNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQD---MFHYTTLSGWATKPLDEKWCCF-- 375
++ +T S FL+ + V MFH + L E+ F
Sbjct: 311 PFLVGLHSCFQTTSR--------LFLVIEYVNGGDLMFHMQR-----QRKLPEEHARFYA 357
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+I + +H GI +RD+KL+NVL+ G +KLTD+G+ G+ P D TS
Sbjct: 358 AEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGL-GPGDTTST------ 410
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PFALFA 492
+CG+P ++ PE++ Y F +D WALG+LMF ++ PF +
Sbjct: 411 FCGTPNYIAPEIL--------------RGEEYG-FSVDWWALGVLMFEMMAGRSPFDIIT 455
Query: 493 E 493
+
Sbjct: 456 D 456
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 65.5 bits (158), Expect = 3e-10
Identities = 63/224 (28%), Positives = 100/224 (44%), Gaps = 37/224 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+ +G G QV + + Q+ A+K + +DE + E + KK S+H N+
Sbjct: 25 EVVGNGTYGQVYKGRHV-KTAQLAAIKIMNINEDEEDE-----IKLEINMLKKHSHHRNV 78
Query: 324 IKTF--YIMKTPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF-- 375
+ +I K PS + + W +M+ C + D+ T L E+W +
Sbjct: 79 ATYYGAFIKKLPSSTGKHDQLW-LVMEFCGSGSITDLVKNTKGGS-----LKEEWIAYIC 132
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
++I RG+ H+H + HRDIK +NVL+TD +KL DFG+S D T R
Sbjct: 133 REILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSA-----QLDKTVGRRNT-- 185
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGI 479
+ G+P + PEV+ YD + D W+LGI
Sbjct: 186 FIGTPYWMAPEVIACD---------ESPEATYDS-RSDLWSLGI 219
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 65.5 bits (158), Expect = 3e-10
Identities = 63/224 (28%), Positives = 100/224 (44%), Gaps = 37/224 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+ +G G QV + + Q+ A+K + +DE + E + KK S+H N+
Sbjct: 25 EVVGNGTYGQVYKGRHV-KTAQLAAIKIMNINEDEEDE-----IKLEINMLKKHSHHRNV 78
Query: 324 IKTF--YIMKTPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF-- 375
+ +I K PS + + W +M+ C + D+ T L E+W +
Sbjct: 79 ATYYGAFIKKLPSSTGKHDQLW-LVMEFCGSGSITDLVKNTKGGS-----LKEEWIAYIC 132
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
++I RG+ H+H + HRDIK +NVL+TD +KL DFG+S D T R
Sbjct: 133 REILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSA-----QLDKTVGRRNT-- 185
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGI 479
+ G+P + PEV+ YD + D W+LGI
Sbjct: 186 FIGTPYWMAPEVIACD---------ESPEATYDS-RSDLWSLGI 219
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 65.5 bits (158), Expect = 3e-10
Identities = 63/224 (28%), Positives = 100/224 (44%), Gaps = 37/224 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+ +G G QV + + Q+ A+K + +DE + E + KK S+H N+
Sbjct: 25 EVVGNGTYGQVYKGRHV-KTAQLAAIKIMNINEDEEDE-----IKLEINMLKKHSHHRNV 78
Query: 324 IKTF--YIMKTPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF-- 375
+ +I K PS + + W +M+ C + D+ T L E+W +
Sbjct: 79 ATYYGAFIKKLPSSTGKHDQLW-LVMEFCGSGSITDLVKNTKGGS-----LKEEWIAYIC 132
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
++I RG+ H+H + HRDIK +NVL+TD +KL DFG+S D T R
Sbjct: 133 REILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSA-----QLDKTVGRRNT-- 185
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGI 479
+ G+P + PEV+ YD + D W+LGI
Sbjct: 186 FIGTPYWMAPEVIACD---------ESPEATYDS-RSDLWSLGI 219
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 65.1 bits (157), Expect = 4e-10
Identities = 35/128 (27%), Positives = 63/128 (48%), Gaps = 22/128 (17%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F QI+ + + HS+ HRD+KLEN+L+ G KLTDFG + + +
Sbjct: 138 FAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTR--------ECMTKTTLE 189
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
CG+ ++ PE++ YD FK+D W+LG++++ L+ + F +
Sbjct: 190 TVCGTTVYMAPELI--------------ERRTYDGFKIDIWSLGVILYTLITGYLPFDDD 235
Query: 495 HKDDSKYR 502
+ +K++
Sbjct: 236 DEAKTKWK 243
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 65.1 bits (157), Expect = 4e-10
Identities = 74/308 (24%), Positives = 121/308 (39%), Gaps = 61/308 (19%)
Query: 263 RKTLGEGGSSQV-MTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
R+TLGEG +V + H Y+ +Q ALK + D H + + K+ H
Sbjct: 37 RETLGEGSFGKVKLATH--YKTQQKVALKFISRQLLKKSD--MHMRVEREISYLKLLRHP 92
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
+IIK + ++ TP+ +++ ++F Y T+ DE F+QI
Sbjct: 93 HIIKLYDVITTPT-------DIVMVIEYAGGELFDYIVEKKRMTE--DEGRRFFQQIICA 143
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
I + H I HRD+K EN+L+ D +K+ DFG+S ++ ++ CGSP
Sbjct: 144 IEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNI--------MTDGNFLKTSCGSPN 195
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+ PEV+ Y ++D W+ GI+++ + L DD
Sbjct: 196 YAAPEVI--------------NGKLYAGPEVDVWSCGIVLYVM-----LVGRLPFDDEFI 236
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
+ P F PG A + R++ D R TI
Sbjct: 237 PNLFKKVNSCVYVMPDFLSPG--------------------AQSLIRRMIVADPMQRITI 276
Query: 562 DDLFNDPW 569
++ DPW
Sbjct: 277 QEIRRDPW 284
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 65.1 bits (157), Expect = 4e-10
Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 34/219 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+TLG+G ++V ++V ALK ++ DE D + + + + +H NI
Sbjct: 27 RTLGQGNLAKVKLGKHFQTNEKV-ALKM--VYNDELEDKDTWKRLQREVTILRQLHHPNI 83
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I + + + P + + ++ + + L T+ + F+QI I
Sbjct: 84 ITLYQVFRVPKYT---VLALEYMDTDLHSMVVKHNRLDECTTRKI------FRQIVHAID 134
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
+ H +AHRD+KLEN+L+ +KLTDFG+S + + TS CG+P +
Sbjct: 135 YCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGSFLSTS--------CGTPHYA 186
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMF 482
PEV+ YD +D W GIL++
Sbjct: 187 APEVI--------------QGRYYDGCDVDVWGCGILLY 211
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 65.1 bits (157), Expect = 4e-10
Identities = 71/298 (23%), Positives = 124/298 (40%), Gaps = 61/298 (20%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFK---LFKDETPDHFYHRCITEFMIAKKVSNH 320
K LG+G +VM + K +VYA+K K + +D+ D +TE I H
Sbjct: 412 KVLGKGSFGKVMLAE-LKGKDEVYAVKVLKKDVILQDDDVDC----TMTEKRILALARKH 466
Query: 321 VNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQI 378
+ + + +T + F + + V D+ S +P + ++
Sbjct: 467 PYLTQLYCCFQT--------KDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAA--EV 516
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCG 438
+ +H G+ +RD+KL+N+L+ G KL DFG+ GI + T+ +CG
Sbjct: 517 TSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTT-------FCG 569
Query: 439 SPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PFA------ 489
+P ++ PE++ Y P +D WALG+LM+ ++ PF
Sbjct: 570 TPDYIAPEIL--------------QELEYGP-SVDWWALGVLMYEMMAGQPPFEADNEDD 614
Query: 490 LFAEAHKDDSKY-----RHYIAFYEQFNKHSPHFRKPGVYRSGPG----AEHPEFSKL 538
LF DD Y + ++ + F +PH ++ G S G +HP F ++
Sbjct: 615 LFESILHDDVLYPVWLSKEAVSILKAFMTKNPH-KRLGCVASQNGEDAIKQHPFFKEI 671
>CE12478 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 484
Score = 65.1 bits (157), Expect = 4e-10
Identities = 70/298 (23%), Positives = 129/298 (42%), Gaps = 43/298 (14%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K LG+G QV V + + + ALKR + + + E I + ++ H N+
Sbjct: 29 KPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQDR--EYIDAIRKEITIQESLTGHENV 86
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I+ + + + FL D+ Y ++ + L+E FKQ+ G++
Sbjct: 87 IQVL------GKESDAQFCYMFLEYADGGDL--YEKITSGCSFSLEEAHSYFKQLVNGLK 138
Query: 384 HMHSLGIAHRDIKLENVLVTDYGA-----LKLTDFGIST-YGIKDPEDPTSERIKIRGYC 437
+H +AHRDIK EN+++T G LK+ DFG++T Y K E +R C
Sbjct: 139 FLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAELIFEQR------C 192
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GS +V PE+ Y ++D W+ G+++ ++ +
Sbjct: 193 GSVEYVAPEI--------------YTGAQYRGPQIDIWSAGVVLLAMLTRQLPWEFPCMT 238
Query: 498 DSKY----RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLL 551
+ +Y ++ +A + +N+ S +K PG+E+ + + +++S C RLL
Sbjct: 239 NKRYFFWMKNRVAHIDAWNELSCRAKKLLWKMLSPGSENR--ATIEEIQSS-ACNRLL 293
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 65.1 bits (157), Expect = 4e-10
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 30/167 (17%)
Query: 319 NHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQI 378
NH NII+ + + + + L+ + Y +S + P E F+QI
Sbjct: 131 NHPNIIQIYEVFEN--------KDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQI 182
Query: 379 ARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCG 438
+ + H +AHRD+KLEN+L+ K+ DFG+S Y +++ + +CG
Sbjct: 183 TSAVLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNY--------FADKNLLTTFCG 234
Query: 439 SPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
SP + PE++ Y ++D W+LGIL++ LV
Sbjct: 235 SPLYASPEII--------------NGTPYKGPEVDCWSLGILLYTLV 267
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 64.7 bits (156), Expect = 5e-10
Identities = 36/132 (27%), Positives = 65/132 (48%), Gaps = 22/132 (16%)
Query: 368 LDEKWCC--FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPED 425
L E C F Q+ G+ +MH G+ HRD+KLEN+L+ + L +TDFG +D E
Sbjct: 147 LKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNE- 205
Query: 426 PTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++ CGSP + PE+++ Y+ K D W+ G++++ ++
Sbjct: 206 ------LMKTSCGSPCYAAPELVV-------------STKAYEARKADVWSCGVILYAML 246
Query: 486 CPFALFAEAHKD 497
+ + + H++
Sbjct: 247 AGYLPWDDDHEN 258
>Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 382
Score = 64.7 bits (156), Expect = 5e-10
Identities = 56/198 (28%), Positives = 85/198 (42%), Gaps = 44/198 (22%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSERIK 432
+ I I+ +HS IAHRD+K EN+L T LKLTDFG + ++ T ++
Sbjct: 148 RDIGTAIQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFA-------KETTQNALQ 200
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFA 492
C +P +V PEV+ YD D W+LG++M+ L+C F
Sbjct: 201 TP--CYTPYYVAPEVL--------------GPEKYDK-SCDMWSLGVIMYILLCGFP--- 240
Query: 493 EAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLD 552
FY + K + G +PE+S++ S +A ++ LL
Sbjct: 241 -------------PFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEV-SEDAKQLIRLLLK 286
Query: 553 PDASTRYTIDDLFNDPWM 570
D + R TI N PW+
Sbjct: 287 TDPTERLTITQFMNHPWI 304
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 64.7 bits (156), Expect = 5e-10
Identities = 58/224 (25%), Positives = 97/224 (42%), Gaps = 35/224 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRKK--QVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHV 321
K LG+G +V V + Q+YA+K K + D R E I +V NH
Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRV--RSKMERDILAEV-NHP 119
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
I+K Y +T +L+ ++ +T LS ++ ++A
Sbjct: 120 FIVKLHYAFQTEGK--------LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALA 171
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ H+HSLGI +RD+K EN+L+ + G +K+TDFG+S I + + +CG+
Sbjct: 172 LDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDK-------RAYSFCGTIE 224
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++ PEV+ D W+ G+LMF ++
Sbjct: 225 YMAPEVVNRRGHTQSA---------------DWWSFGVLMFEML 253
>CE20717 [T] KOG0583 Serine/threonine protein kinase
Length = 301
Score = 64.7 bits (156), Expect = 5e-10
Identities = 33/111 (29%), Positives = 55/111 (48%), Gaps = 22/111 (19%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+Q+ I ++H GI HRD+KLEN+L+ G +KL DFG + + R + R
Sbjct: 130 FRQLIEAINYLHKRGIVHRDVKLENILIDGNGDIKLIDFGFARH--------IERRERSR 181
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+CG+ P+ P++ Y+ + D +A GI++F +V
Sbjct: 182 SFCGTQPYTCPQI--------------TKYRPYEAYAADYYACGIVLFTMV 218
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 64.7 bits (156), Expect = 5e-10
Identities = 65/258 (25%), Positives = 108/258 (41%), Gaps = 40/258 (15%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K LG+G +V + ++V A+K K K E R E I V +H NI
Sbjct: 86 KKLGQGTYGKVQLGINKETGQEV-AIKTIKKCKIEAEADLV-RIRREVQIMSSV-HHPNI 142
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I + + + R L+ + Y LS +E F+Q+A +
Sbjct: 143 IHIYEVFEN--------REKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVY 194
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
+ H I HRD+KLEN+L+ + G K+ DFG+S + ++ + +CGSP +
Sbjct: 195 YCHKHKICHRDLKLENILLDEKGNAKIADFGLS--------NVFDDQRLLGTFCGSPLYA 246
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRH 503
PE++ Y ++D W+LG+L++ LV + D S ++
Sbjct: 247 SPEIV--------------EGTPYQGPEVDCWSLGVLLYTLV-----YGSMPFDGSNFKR 287
Query: 504 YIAFYEQFNKHSPHFRKP 521
+ Q + + P RKP
Sbjct: 288 LVKQISQGDYYEP--RKP 303
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 64.7 bits (156), Expect = 5e-10
Identities = 50/199 (25%), Positives = 87/199 (43%), Gaps = 44/199 (22%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLV---TDYGALKLTDFGISTYGIKDPEDPTSERI 431
F Q+ ++++H GI HRD+K +NVL+ + LK++DFG+S + KD
Sbjct: 267 FYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDS-------- 318
Query: 432 KIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALF 491
+R CG+P +V PEV+I K+D W+LG+++F +
Sbjct: 319 VMRTLCGTPLYVAPEVLITGGREAYTK------------KVDIWSLGVVLFTCL------ 360
Query: 492 AEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLL 551
+ F +++ + K G + G HP + + S A + ++L
Sbjct: 361 ----------SGTLPFSDEYGTPAAQQIKKGRFAYG----HPSWKSV-SQRAKLLINQML 405
Query: 552 DPDASTRYTIDDLFNDPWM 570
D R +IDD+ W+
Sbjct: 406 IVDPERRPSIDDVLQSSWL 424
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 64.3 bits (155), Expect = 7e-10
Identities = 47/197 (23%), Positives = 87/197 (43%), Gaps = 47/197 (23%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+QI + ++H + HRD+K+EN+L++ G +K+ DFG+S + ++R
Sbjct: 248 RQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNL--------YRRQSRLRT 299
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
+CGS PE++ Y ++D W+ GI+++ LVC F
Sbjct: 300 FCGSLYFAAPELL--------------NAQPYIGPEVDVWSFGIVLYVLVCGKVPF---- 341
Query: 496 KDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDA 555
DD ++ A + + K + E+P + S + + R+L D
Sbjct: 342 -DD---QNMSALHAKIKKGT--------------VEYPSYL---SSDCKGLLSRMLVTDP 380
Query: 556 STRYTIDDLFNDPWMAK 572
R T++++ N PWM +
Sbjct: 381 LKRATLEEVLNHPWMIR 397
>CE27899 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 318
Score = 64.3 bits (155), Expect = 7e-10
Identities = 72/313 (23%), Positives = 116/313 (37%), Gaps = 59/313 (18%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAK---KVSNHVN 322
L EG QV S A+K+ + F TEF I K K+ H N
Sbjct: 27 LSEGTYGQVSLYESSKNPDVKIAVKQISTAGQS--ERFVEHIKTEFAIHKGLSKIGGHRN 84
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
+I + K L+++ + L + + C FKQ+ G+
Sbjct: 85 VISMMEMRKGSDCYT--------LLKEYADGGDLFKKLETEGEQYSENAQCFFKQLISGL 136
Query: 383 RHMHSLGIAHRDIKLENVLVTDY------GALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+ +H I HRDIKLEN+L+ LK+ DFG++T + D E + +
Sbjct: 137 KFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVD-----GEELMLVDN 191
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHK 496
CGSPP+ PEV + D W+ G+++ ++ + AH+
Sbjct: 192 CGSPPYAAPEV--------------YSKQGHRGPPTDVWSSGVILMAMLTAGLPWDCAHR 237
Query: 497 DDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAS 556
D Y +I FR ++ S A + ++L + S
Sbjct: 238 KDVDYAAWI---------DKKFRTDNLWND------------ISDRALALLRKILCVNVS 276
Query: 557 TRYTIDDLFNDPW 569
R +I+ + DPW
Sbjct: 277 ERVSIEQIEADPW 289
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 64.3 bits (155), Expect = 7e-10
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 34/169 (20%)
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQ 377
H +I + F ++ TPS FL+ + V ++F Y T G P+ E F+Q
Sbjct: 81 HPHITRLFRVISTPSD--------IFLVMELVSGGELFSYITRKG--ALPIRESRRYFQQ 130
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I G+ + H+ I HRD+K EN+L+ +K+ DFG+S Y ++ + C
Sbjct: 131 IISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNY--------MTDGDLLSTAC 182
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
GSP + PE++ Y ++D W+ G++++ ++C
Sbjct: 183 GSPNYAAPELI--------------SNKLYVGPEVDLWSCGVILYAMLC 217
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 63.9 bits (154), Expect = 9e-10
Identities = 40/120 (33%), Positives = 60/120 (49%), Gaps = 23/120 (19%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+I + H+H LGI +RD+KLENVL+ G + LTDFG+S E T E+ + +
Sbjct: 144 EIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLS------KEFLTEEKERTFSF 197
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV---CPFALFAE 493
CG+ ++ PE++ +D W+LGIL+F L+ PF L E
Sbjct: 198 CGTIEYMAPEIIRSKTGHGKA--------------VDWWSLGILLFELLTGASPFTLEGE 243
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 63.9 bits (154), Expect = 9e-10
Identities = 57/221 (25%), Positives = 95/221 (42%), Gaps = 33/221 (14%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
LG GG +V + ++V K+ + H R TE + +S H NI +
Sbjct: 17 LGSGGFGKVRLATHLLTNQKV----AIKIIDKKQLGHDLPRVQTEMDALRNLS-HQNICR 71
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCFKQIARGIRH 384
++ ++T + +M+ C +MF Y + E F+Q+ I
Sbjct: 72 LYHYIETED-------KFFIVMEYCSGGEMFDYIVRKERLEE--SEARHFFRQLVSAIAF 122
Query: 385 MHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVP 444
+HS G AHRD+K EN+L+T+ LKL DFG+ E ++ + CGSP +
Sbjct: 123 VHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCA----KTEKGRIDKHNLDTCCGSPAYAA 178
Query: 445 PEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE++ Y + D W++GIL++ L+
Sbjct: 179 PELI--------------QGLQYKGNEADVWSMGILLYTLL 205
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 63.9 bits (154), Expect = 9e-10
Identities = 56/199 (28%), Positives = 83/199 (41%), Gaps = 51/199 (25%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
FK + I + H +G+ HRDIK EN+L+T G ++L DFG++ K +
Sbjct: 205 FKDLMLVINYCHEMGVVHRDIKPENILLTAAGKIQLADFGLAMRIAKGQ--------TLS 256
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL---VCPFALF 491
G GSP +V PEV+ + K+D W+ G+L++ L V PF
Sbjct: 257 GLAGSPAYVAPEVLSENYSE----------------KVDVWSAGVLLYALLSGVLPF--- 297
Query: 492 AEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLL 551
K DS A +E F GV+ S S A + R+L
Sbjct: 298 ----KGDS----LDAIFEAIKNVKLDF-NTGVWES------------VSKPARDLLARML 336
Query: 552 DPDASTRYTIDDLFNDPWM 570
+ S R T D++ PW+
Sbjct: 337 TREESARITADEVLRHPWI 355
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 63.9 bits (154), Expect = 9e-10
Identities = 65/240 (27%), Positives = 107/240 (44%), Gaps = 46/240 (19%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+T+G+G + V ++ YALK K K +H E I ++V H NI
Sbjct: 50 RTIGDGNFAVVKECVERSTARE-YALKIIKKSKCRGKEHMIQN---EVSILRRVK-HPNI 104
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQIARG 381
+ M P+ +L+ + V+ D+F T + T+ D + +A
Sbjct: 105 VLLIEEMDVPTE--------LYLVMELVKGGDLFDAITSTNKYTER-DASGMLYN-LASA 154
Query: 382 IRHMHSLGIAHRDIKLENVLVTDY----GALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I+++HSL I HRDIK EN+LV ++ +LKL DFG++T + P + C
Sbjct: 155 IKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-VDGP---------LYTVC 204
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
G+P +V PE++ + K+D WA G++ + L+C F F + D
Sbjct: 205 GTPTYVAPEIIAETGYG---------------LKVDIWAAGVITYILLCGFPPFRGSGDD 249
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 63.5 bits (153), Expect = 1e-09
Identities = 48/187 (25%), Positives = 83/187 (43%), Gaps = 31/187 (16%)
Query: 299 TPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYT 358
TPD + E +I K + NH N+++ + + +T + +L+ + + +
Sbjct: 70 TPDALPYGIEREIIIMKLL-NHPNVLRLYDVWET--------NTDLYLVLEYAEKGELFN 120
Query: 359 TLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTY 418
L P E F+QI G+ + H+LGI HRD+K EN+L+ +K+ DFG++
Sbjct: 121 LLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL 180
Query: 419 GIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALG 478
+ TS CGSP + PE++ Y F D W+ G
Sbjct: 181 ETEGKLLETS--------CGSPHYAAPEIV--------------SGIPYQGFASDVWSCG 218
Query: 479 ILMFNLV 485
+++F L+
Sbjct: 219 VILFALL 225
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 63.5 bits (153), Expect = 1e-09
Identities = 42/158 (26%), Positives = 76/158 (47%), Gaps = 30/158 (18%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+IA G+ + S GI +RD+KL+NV++ G +K+ DFG+ I D + + +
Sbjct: 449 EIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWD-------GVTTKTF 501
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPF--KMDTWALGILMFNLVCPFALFAEA 494
CG+P ++ PE++ Y P+ +D WA G+L++ ++ A F
Sbjct: 502 CGTPDYIAPEII-----------------AYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 544
Query: 495 HKDD---SKYRHYIAFYEQFNKHSPHFRKPGVYRSGPG 529
+D+ S H +A+ + +K + K G+ PG
Sbjct: 545 DEDELFQSIMEHNVAYPKSMSKEAVAICK-GLMTKHPG 581
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 63.5 bits (153), Expect = 1e-09
Identities = 57/194 (29%), Positives = 89/194 (45%), Gaps = 46/194 (23%)
Query: 309 TEFMIAKKVS-----NHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLS 361
TE +I +VS H NII M+T + FL+ + V+ D+F T S
Sbjct: 255 TEHLIENEVSILRRVKHPNIIMLVEEMETATE--------LFLVMELVKGGDLFDAITSS 306
Query: 362 GWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDY----GALKLTDFGIST 417
T+ + +A +R++H L I HRDIK EN+LV +Y +LKL DFG++T
Sbjct: 307 TKYTER--DGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLAT 364
Query: 418 YGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWAL 477
++ P + CG+P +V PE++ + K+D WA
Sbjct: 365 V-VEGP---------LYTVCGTPTYVAPEIIAETGYG---------------LKVDIWAA 399
Query: 478 GILMFNLVCPFALF 491
G++ + L+C F F
Sbjct: 400 GVITYILLCGFPPF 413
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 63.5 bits (153), Expect = 1e-09
Identities = 35/136 (25%), Positives = 62/136 (44%), Gaps = 23/136 (16%)
Query: 358 TTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST 417
T + P+D F + + ++H+ GI HRD+K +N+LVT G +KLTDFG+S
Sbjct: 126 TLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSK 185
Query: 418 YGIKDPE--------DPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDP 469
G+ + + + CG+P ++ PEV++
Sbjct: 186 VGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGK-------------- 231
Query: 470 FKMDTWALGILMFNLV 485
+D WA+GI+++ +
Sbjct: 232 -PVDWWAMGIILYEFL 246
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 63.5 bits (153), Expect = 1e-09
Identities = 42/158 (26%), Positives = 76/158 (47%), Gaps = 30/158 (18%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+IA G+ + S GI +RD+KL+NV++ G +K+ DFG+ I D + + +
Sbjct: 449 EIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWD-------GVTTKTF 501
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPF--KMDTWALGILMFNLVCPFALFAEA 494
CG+P ++ PE++ Y P+ +D WA G+L++ ++ A F
Sbjct: 502 CGTPDYIAPEII-----------------AYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 544
Query: 495 HKDD---SKYRHYIAFYEQFNKHSPHFRKPGVYRSGPG 529
+D+ S H +A+ + +K + K G+ PG
Sbjct: 545 DEDELFQSIMEHNVAYPKSMSKEAVAICK-GLMTKHPG 581
>ECU08g1480 [R] KOG0586 Serine/threonine protein kinase
Length = 467
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/196 (25%), Positives = 85/196 (42%), Gaps = 48/196 (24%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F Q+ R + ++H+ I HRD+KLENV+++ +K+ DFG+ST+ D +S +R
Sbjct: 109 FIQMLRAVDYLHTHSIVHRDLKLENVMISG-ETVKICDFGLSTF-----YDSSS---VLR 159
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
YCG+P PPE+M Y ++D W LG++++ +V F +
Sbjct: 160 DYCGTPQCAPPEIM--------------NGIPYIGPEVDIWCLGVILYAMVHGKLPFEDG 205
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
S RH I + ++ S E + + ++PD
Sbjct: 206 DTKLSS-RHAIVSKMRIDESL------------------------SSELRDLIRKTIEPD 240
Query: 555 ASTRYTIDDLFNDPWM 570
S R +D + PW+
Sbjct: 241 RSMRIKMDQMMEHPWI 256
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 63.5 bits (153), Expect = 1e-09
Identities = 40/140 (28%), Positives = 69/140 (48%), Gaps = 27/140 (19%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
++A + +H I +RD+KL+N+L+ G +KL DFG+S G+ +ER R +
Sbjct: 478 EVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGV-------TERQTTRTF 530
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKM--DTWALGILMFNLVCPFALFAEA 494
CG+P ++ PE++ YDP+ + D W+ G+L+F + A F E
Sbjct: 531 CGTPNYMAPEIV-----------------SYDPYSIAADWWSFGVLLFEFMAGQAPF-EG 572
Query: 495 HKDDSKYRHYIAFYEQFNKH 514
+ + +R+ F KH
Sbjct: 573 DDETTVFRNIKDKKAVFPKH 592
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 63.2 bits (152), Expect = 2e-09
Identities = 75/319 (23%), Positives = 129/319 (39%), Gaps = 74/319 (23%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
R LG G S+V+ R +++ A+K CI + + K + N
Sbjct: 23 RDVLGTGAFSEVILAED-KRTQKLVAIK----------------CIAKEALEGKEGSMEN 65
Query: 323 IIKTFYIMKTPSV--------SNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKW 372
I + +K P++ S G +L+ Q V ++F G+ T+ D
Sbjct: 66 EIAVLHKIKHPNIVALDDIYESGGH----LYLIMQLVSGGELFDRIVEKGFYTER-DASR 120
Query: 373 CCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIK 432
F Q+ ++++H LGI HRD+K EN+L Y + + IS +G+ EDP S
Sbjct: 121 LIF-QVLDAVKYLHDLGIVHRDLKPENLLY--YSLDEDSKIMISDFGLSKMEDPGS---V 174
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFA 492
+ CG+P +V PEV+ +D W++G++ + L+C + F
Sbjct: 175 LSTACGTPGYVAPEVLAQKPYSKA---------------VDCWSIGVIAYILLCGYPPFY 219
Query: 493 EAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLD 552
+ ++D+K +EQ K F P Y +F + L++
Sbjct: 220 D--ENDAK------LFEQILKAEYEFDSP--YWDDISDSAKDFIR-----------HLME 258
Query: 553 PDASTRYTIDDLFNDPWMA 571
D R+T + PW+A
Sbjct: 259 KDPEKRFTCEQALQHPWIA 277
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/171 (25%), Positives = 79/171 (45%), Gaps = 30/171 (17%)
Query: 316 KVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF 375
K+ +H +IIK + +M+T +S +L+ + ++ + L+ E F
Sbjct: 72 KMLDHPHIIKLYQVMET--------KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKF 123
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
QI + + H I HRD+K EN+L+ + +K+ DFG + K E +
Sbjct: 124 WQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNF-FKSGE-------LLAT 175
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
+CGSPP+ PEV Y+ ++D W++G++++ LVC
Sbjct: 176 WCGSPPYAAPEVF--------------EGQQYEGPQLDIWSMGVVLYVLVC 212
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 63.2 bits (152), Expect = 2e-09
Identities = 37/141 (26%), Positives = 65/141 (45%), Gaps = 33/141 (23%)
Query: 358 TTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST 417
T L P+D F + + ++H+ GI HRD+K +N+L+T G +KLTDFG+S
Sbjct: 599 TLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSK 658
Query: 418 YGI-------------KDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXX 464
G+ KD + +++ CG+P ++ PEV++
Sbjct: 659 MGLMSLTTNLYEGHIEKDAREFLDKQV-----CGTPEYIAPEVILRQGYGK--------- 704
Query: 465 XXYDPFKMDTWALGILMFNLV 485
+D WA+GI+++ +
Sbjct: 705 ------PVDWWAMGIILYEFL 719
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 62.8 bits (151), Expect = 2e-09
Identities = 59/203 (29%), Positives = 93/203 (45%), Gaps = 46/203 (22%)
Query: 375 FKQIARGIRHMH-SLGIAHRDIKLENVLVTDYGALKLTDFGI-STYGIKDPEDPTSERIK 432
F+Q+ I ++H G+AHRDIK EN+L+ G LKL DFG+ S + KD S +
Sbjct: 122 FQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQR 181
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV---CPFA 489
GSPP++ PEV+ Y + D W++GIL+F L+ P+
Sbjct: 182 -----GSPPYMAPEVL-------------YSEEGYYADRTDIWSIGILLFVLLTGQTPWE 223
Query: 490 LFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLR 549
L + ++D ++ F E G GP ++ EF+ L + +
Sbjct: 224 LPSLENED------FVFFIE----------NDGNLNWGPWSK-IEFTHLNLLR------K 260
Query: 550 LLDPDASTRYTIDDLFNDPWMAK 572
+L PD + R T+ L PW+ +
Sbjct: 261 ILQPDPNKRVTLKALKLHPWVLR 283
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 62.8 bits (151), Expect = 2e-09
Identities = 55/221 (24%), Positives = 96/221 (42%), Gaps = 29/221 (13%)
Query: 266 LGEGGSSQVMTV--HSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
LGEG +V V ++ V LK+ KL + + + E + +++ H N+
Sbjct: 55 LGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKK---EIQLLRRL-RHKNV 110
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I+ ++ N K+ +M+ CV M P+ + F Q+ G+
Sbjct: 111 IQLVDVLY-----NEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLE 165
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
++HS GI H+DIK N+L+T G LK++D G++ + P + R GSP
Sbjct: 166 YLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVA-----EALHPFAADDTCRTSQGSPAFQ 220
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
PPE+ + FK+D W+ G+ ++N+
Sbjct: 221 PPEI-------------ANGLDTFSGFKVDIWSAGVTLYNI 248
>CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 370
Score = 62.8 bits (151), Expect = 2e-09
Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 38/198 (19%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
KQ+ G+ +MH+ I HRD+KLEN+L D + ++DFG +T + P K+R
Sbjct: 27 KQLFDGVEYMHARDIVHRDLKLENILCIDEERIVISDFGFAT---RIPRGK-----KLRD 78
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
CG+P ++ PE + ++D WALG++M+ L+ A F
Sbjct: 79 LCGTPGYLAPETIRCQWYDNAEGYS---------LEVDEWALGVIMYTLLAGCAPF---- 125
Query: 496 KDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDA 555
+R + + FR + +++ + + EA + +LL DA
Sbjct: 126 ----YHRKQLMMLRLIQQGKFEFR------------NEQWANI-TAEAKNLITQLLQVDA 168
Query: 556 STRYTIDDLFNDPWMAKI 573
+ R + + WM I
Sbjct: 169 TKRISSKECLAHEWMIPI 186
>CE21239 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 62.8 bits (151), Expect = 2e-09
Identities = 39/109 (35%), Positives = 58/109 (52%), Gaps = 23/109 (21%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
Q+ RG++ MHS+ IAHRDIKLEN+++ D +KL+DFG + K E S +
Sbjct: 200 QLIRGLQFMHSINIAHRDIKLENIILFD-NCVKLSDFG---FVRKMDESALSST-----F 250
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
CGS + PE++ Y+PF D W+LG++ F +V
Sbjct: 251 CGSKSYSAPELL--------------RGIVYNPFLSDVWSLGVVGFVMV 285
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 62.8 bits (151), Expect = 2e-09
Identities = 61/203 (30%), Positives = 92/203 (45%), Gaps = 38/203 (18%)
Query: 285 QVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTF--YIMKTPSVSNGPKRS 342
Q+ A+K + +DE + E + KK SNH NI + +I K+P G
Sbjct: 56 QLAAIKVMDVTEDEEEE-----IKLEINVLKKYSNHRNIATYYGAFIKKSPP---GKDDQ 107
Query: 343 WAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIRHMHSLGIAHRDIK 396
+M+ C V D+ T + L E+W + ++I RG+ ++HS + HRDIK
Sbjct: 108 LWLVMEYCGAGSVTDLVKSTK-----GQSLKEEWIAYICREILRGLSYLHSNKVIHRDIK 162
Query: 397 LENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXX 456
+NVL+TD +KL DFG+S D T R + G+P + PEV+
Sbjct: 163 GQNVLLTDNAEVKLVDFGVSA-----QLDRTIGRRNT--FIGTPYWMAPEVIACD----- 210
Query: 457 XXXXXXXXXXYDPFKMDTWALGI 479
YD + D W+LGI
Sbjct: 211 ----ENPDATYDN-RSDLWSLGI 228
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 62.8 bits (151), Expect = 2e-09
Identities = 49/182 (26%), Positives = 84/182 (45%), Gaps = 34/182 (18%)
Query: 316 KVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWC 373
K+ H +IIK + ++ TPS F++ + V ++F Y G + ++
Sbjct: 81 KLFRHPHIIKLYQVISTPSD--------IFMIMEYVSGGELFDYIVKHGKLQEHQARRF- 131
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKI 433
F+QI G+ + H I HRD+K EN+L+ +K+ DFG+S + D E +
Sbjct: 132 -FQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNM-MLDGE-------FL 182
Query: 434 RGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAE 493
R CGSP + PEV+ Y ++D W+ G++++ L+C F +
Sbjct: 183 RTSCGSPNYAAPEVI--------------SGKLYAGPEVDIWSCGVILYALLCGTLPFDD 228
Query: 494 AH 495
H
Sbjct: 229 EH 230
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 62.4 bits (150), Expect = 3e-09
Identities = 59/237 (24%), Positives = 94/237 (38%), Gaps = 58/237 (24%)
Query: 353 DMFHYTTLSGWATKPLDEKWCC--FKQIARGIRHMHSLGIAHRDIKLENVLV-TDYGALK 409
++FHY G PL E+ QI + H H HRD+KLEN+L+ + +K
Sbjct: 89 ELFHYIRKHG----PLSEREAAHYLSQILDAVAHCHRFRFRHRDLKLENILIKVNEQQIK 144
Query: 410 LTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDP 469
+ DFG++T +P D E YCGS ++ PE++ Y
Sbjct: 145 IADFGMATV---EPNDSCLE-----NYCGSLHYLAPEIV--------------SHKPYRG 182
Query: 470 FKMDTWALGILMFNLVCPFALFAEAHKD--DSKYRHYIAFYEQFNKHSPHFRKPGVYRSG 527
D W+ G+++++L+ F + D +K RH G Y
Sbjct: 183 APADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRH------------------GAY--- 221
Query: 528 PGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMAKIESCFXXXXXXP 584
+ S A + R+LD + STR TI ++F+ P++ S P
Sbjct: 222 ------DLPSSISSAAQDLLHRMLDVNPSTRITIPEVFSHPFLMGCTSLSSMDSTTP 272
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 62.4 bits (150), Expect = 3e-09
Identities = 36/141 (25%), Positives = 64/141 (44%), Gaps = 33/141 (23%)
Query: 358 TTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST 417
T L P+D F + + ++H+ GI HRD+K +N+L+T G +KLTDFG+S
Sbjct: 284 TLLKNMGPLPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSK 343
Query: 418 YGI-------------KDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXX 464
G+ KD + +++ CG+P ++ PEV+
Sbjct: 344 IGLMSMATNLYEGHIEKDAREFIDKQV-----CGTPEYIAPEVIFRQGYGK--------- 389
Query: 465 XXYDPFKMDTWALGILMFNLV 485
+D WA+G++++ +
Sbjct: 390 ------PVDWWAMGVVLYEFL 404
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 62.4 bits (150), Expect = 3e-09
Identities = 75/311 (24%), Positives = 128/311 (41%), Gaps = 59/311 (18%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G G S+V+ V +Q YA+K + E + C +E + ++V H NII+
Sbjct: 104 IGRGSFSRVVRVEH-RATRQPYAIKMIETKYREGREV----CESELRVLRRV-RHANIIQ 157
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHM 385
+ +T +R + + ++F G T+ + + + G+R++
Sbjct: 158 LVEVFETQ------ERVYMVMELATGGELFDRIIAKGSFTER--DATRVLQMVLDGVRYL 209
Query: 386 HSLGIAHRDIKLENVLVTDYGA---LKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
H+LGI HRD+K EN+L G + +TDFG+++ K + ++ CG+P +
Sbjct: 210 HALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKK------GDDCLMKTTCGTPEY 263
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYR 502
+ PEV++ +D WALG++ + L+ F +DD++ R
Sbjct: 264 IAPEVLVRKPYTN---------------SVDMWALGVIAYILLSGTMPF----EDDNRTR 304
Query: 503 HYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTID 562
Y Q + G Y S G P S L A RLL D R T
Sbjct: 305 ----LYRQILR--------GKY-SYSGEPWPSVSNL----AKDFIDRLLTVDPGARMTAL 347
Query: 563 DLFNDPWMAKI 573
PW+ +
Sbjct: 348 QALRHPWVVSM 358
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 62.4 bits (150), Expect = 3e-09
Identities = 58/239 (24%), Positives = 102/239 (42%), Gaps = 39/239 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G + V ++ + V K+ D I + + K+ H NI
Sbjct: 31 KTIGQGHFAVVKLAKHVFTGEMVAV----KIIDKTKMDEASTSQIMKEVRCMKLVQHANI 86
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSG--WATKPLDEKWCCFKQIARG 381
++ + ++ T ++ FL+ + H + + L +++ C QI
Sbjct: 87 VRLYEVLDT--------QTKIFLILELGDYDLHDFIIKHEKGVCESLAQQYFC--QIMTA 136
Query: 382 IRHMHSLGIAHRDIKLENVLVTD-YGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSP 440
I + H L + HRD+K ENV+ + G +KLTDFG S + TS CGS
Sbjct: 137 IDYCHQLHVVHRDLKPENVVFFEKLGMVKLTDFGFSNSYEPGEQLNTS--------CGSL 188
Query: 441 PHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDS 499
+ PE+++ YD +D W+LG++++ LVC F EA+ ++
Sbjct: 189 AYSAPEILL--------------GDSYDAPAVDVWSLGVILYMLVCGRLPFQEANDSET 233
>CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 294
Score = 62.4 bits (150), Expect = 3e-09
Identities = 57/221 (25%), Positives = 90/221 (39%), Gaps = 29/221 (13%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K +G+G S+V + V ALK+ ++F + C+ E + K++ NHVN+
Sbjct: 27 KKIGKGQFSEVFRAQCTWVDLHV-ALKKIQVF-EMVDQKARQDCLKEIDLLKQL-NHVNV 83
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I+ + + N L + G P W F Q+AR +
Sbjct: 84 IRYY----ASFIDNNQLNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALA 139
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
HMHS I HRDIK NV +T G +KL D G+ + +S+ G+P ++
Sbjct: 140 HMHSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFF-------SSKTTAAHSLVGTPYYM 192
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
PE + S FK D W+ G L++ +
Sbjct: 193 SPERIQESGYN---------------FKSDLWSTGCLLYEM 218
>7302913 [T] KOG1345 Serine/threonine kinase
Length = 577
Score = 62.4 bits (150), Expect = 3e-09
Identities = 58/202 (28%), Positives = 87/202 (42%), Gaps = 38/202 (18%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLV--TDYGALKLTDFGISTYGIKDPEDPTSERIKI 433
KQ+A I +MHS I HRDIKL+NVL+ +D+ +KL DFG S PT ++
Sbjct: 128 KQLASAIDYMHSKDIVHRDIKLDNVLIYRSDFQRIKLCDFGESF--------PTGSTVER 179
Query: 434 RGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAE 493
R P+ PPEV+ + DP D W GI++F + + +
Sbjct: 180 RNEW--LPYSPPEVLEIKPEGSYKA---------DP-SHDVWQFGIVIFVCLTGCLPWQK 227
Query: 494 AHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDP 553
A DD +Y Y+A+ G P P KL + A R+ R
Sbjct: 228 AASDDPRYVRYLAW-------------QGGLMMMPLRRTPRLFKLLTSNAQRMFKRFFAR 274
Query: 554 DASTRYTIDDL---FNDPWMAK 572
++ ++ D+ +D W+AK
Sbjct: 275 ISNRPKSLADVTKFLDDRWLAK 296
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 62.0 bits (149), Expect = 4e-09
Identities = 52/201 (25%), Positives = 85/201 (41%), Gaps = 51/201 (25%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
QI G+ + H L I HRD+K EN+ + +G++K+ +FG+++ I+ P ++
Sbjct: 116 QILCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMAS--IQQPGK------LLQTS 167
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHK 496
CGSP + PE+++ YD D W+ GI+ F L L +
Sbjct: 168 CGSPHYASPEIIM--------------GRSYDGCASDIWSCGIIFFAL-----LTGKLPF 208
Query: 497 DDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAS 556
DD R + Q P P +A + R+LD D+S
Sbjct: 209 DDDNIRSLLLKVCQGQFEMPSNISP--------------------QAQHLLYRMLDVDSS 248
Query: 557 TRYTIDDLFNDPWMAKIESCF 577
TR T++ + P++ SCF
Sbjct: 249 TRITMEQIREHPFL----SCF 265
>Hs5803125 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 62.0 bits (149), Expect = 4e-09
Identities = 58/222 (26%), Positives = 87/222 (39%), Gaps = 61/222 (27%)
Query: 352 QDMFHYTTLSGWATKPLDE--KWCCFKQIARGIRHMHSLGIAHRDIKLENVLV-TDYGAL 408
QD+F Y T G PL E C F Q+ I+H HS G+ HRDIK EN+L+ G
Sbjct: 123 QDLFDYITEKG----PLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCA 178
Query: 409 KLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYD 468
KL DFG G ++P ++ + G+ + PPE + Y
Sbjct: 179 KLIDFG---SGALLHDEPYTD------FDGTRVYSPPEWI--------------SRHQYH 215
Query: 469 PFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGP 528
W+LGIL++++VC F + H+ A
Sbjct: 216 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHV-------------------- 255
Query: 529 GAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWM 570
S + + R L P S+R +++++ DPWM
Sbjct: 256 -----------SPDCCALIRRCLAPKPSSRPSLEEILLDPWM 286
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 62.0 bits (149), Expect = 4e-09
Identities = 35/111 (31%), Positives = 60/111 (53%), Gaps = 22/111 (19%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+QI G++++H GI HRD+KL N +T+ LK+ DFG++ ++ PE + +
Sbjct: 128 RQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAA-RLEPPEQ------RKKT 180
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
CG+P +V PEV++ + P + D W+LG +M+ L+C
Sbjct: 181 ICGTPNYVAPEVLL--------------RQGHGP-EADVWSLGCVMYTLLC 216
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 62.0 bits (149), Expect = 4e-09
Identities = 54/226 (23%), Positives = 99/226 (42%), Gaps = 37/226 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKK--QVYALKRFKLFK--DETPDHFYHRCITEFMIAKKVSN 319
+ LG+GG +V V + ++YA+K + K D + R + + K
Sbjct: 84 RVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVK--- 140
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIA 379
H I++ Y +T G K +L+ +C+ +T L D +I
Sbjct: 141 HPFIVELAYAFQT-----GGK---LYLILECLSGGELFTHLEREGIFLEDTACFYLAEIT 192
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ H+HS GI +RD+K EN++++ G +KLTDFG+ ++ E +CG+
Sbjct: 193 LALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLC-------KESIHEGAVTHTFCGT 245
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++ PE+++ S +D W+LG LM++++
Sbjct: 246 IEYMAPEILVRSGHNRA---------------VDWWSLGALMYDML 276
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 62.0 bits (149), Expect = 4e-09
Identities = 62/266 (23%), Positives = 103/266 (38%), Gaps = 57/266 (21%)
Query: 309 TEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPL 368
+E +I + +S H NI+K + +T +L+ + VQ + + P
Sbjct: 329 SEILIIQSLS-HPNIVKLHEVYETDME--------IYLILEYVQGGDLFDAIIESVKFPE 379
Query: 369 DEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLV----TDYGALKLTDFGISTYGIKDPE 424
+ + + + HMH I HRD+K EN+LV LKL DFG++ + ++
Sbjct: 380 PDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVR--- 436
Query: 425 DPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
I CG+P +V PE++ ++D WA G++++ L
Sbjct: 437 -------PIFTVCGTPTYVAPEILSEKGYG---------------LEVDMWAAGVILYIL 474
Query: 485 VCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEAS 544
+C F F +D E FN + + G P + S A
Sbjct: 475 LCGFPPFRSPERDQD---------ELFN----------IIQLGHFEFLPPYWDNISDAAK 515
Query: 545 RVCLRLLDPDASTRYTIDDLFNDPWM 570
+ RLL D RYT + PW+
Sbjct: 516 DLVSRLLVVDPKKRYTAHQVLQHPWI 541
>Hs13649368 [T] KOG0583 Serine/threonine protein kinase
Length = 311
Score = 62.0 bits (149), Expect = 4e-09
Identities = 58/222 (26%), Positives = 87/222 (39%), Gaps = 61/222 (27%)
Query: 352 QDMFHYTTLSGWATKPLDE--KWCCFKQIARGIRHMHSLGIAHRDIKLENVLV-TDYGAL 408
QD+F Y T G PL E C F Q+ I+H HS G+ HRDIK EN+L+ G
Sbjct: 123 QDLFDYITEKG----PLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCA 178
Query: 409 KLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYD 468
KL DFG G ++P ++ + G+ + PPE + Y
Sbjct: 179 KLIDFG---SGALLHDEPYTD------FDGTRVYSPPEWI--------------SRHQYH 215
Query: 469 PFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGP 528
W+LGIL++++VC F + H+ A
Sbjct: 216 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHV-------------------- 255
Query: 529 GAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWM 570
S + + R L P S+R +++++ DPWM
Sbjct: 256 -----------SPDCCALIRRCLAPKPSSRPSLEEILLDPWM 286
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 61.6 bits (148), Expect = 5e-09
Identities = 70/314 (22%), Positives = 127/314 (40%), Gaps = 64/314 (20%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
++TLG G S+V+ + +K L K + E + +K+ H N
Sbjct: 26 KETLGTGAFSEVV----LAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIK-HEN 80
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQIAR 380
I+ I ++P+ +L+ Q V ++F G+ T+ + +Q+
Sbjct: 81 IVALEDIYESPN--------HLYLVMQLVSGGELFDRIVEKGFYTEK--DASTLIRQVLD 130
Query: 381 GIRHMHSLGIAHRDIKLENVLV---TDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
+ ++H +GI HRD+K EN+L + + ++DFG+S K T+ C
Sbjct: 131 AVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTA--------C 182
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
G+P +V PEV+ +D W++G++ + L+C + F + ++
Sbjct: 183 GTPGYVAPEVLAQKPYSKA---------------VDCWSIGVIAYILLCGYPPFYD--EN 225
Query: 498 DSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAST 557
DSK +EQ K F P Y +F + L++ D +
Sbjct: 226 DSK------LFEQILKAEYEFDSP--YWDDISDSAKDFIR-----------NLMEKDPNK 266
Query: 558 RYTIDDLFNDPWMA 571
RYT + PW+A
Sbjct: 267 RYTCEQAARHPWIA 280
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 61.6 bits (148), Expect = 5e-09
Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 45/210 (21%)
Query: 366 KPLDEKWC--CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYG---ALKLTDFGISTYGI 420
K L E C F Q+ ++++H GI HRD+K ENVL++ +K+TDFG S
Sbjct: 317 KRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKI-- 374
Query: 421 KDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGIL 480
E +R CG+P ++ PEV++ Y+ +D W+LG++
Sbjct: 375 ------LGETSLMRTLCGTPTYLAPEVLV-----------SVGTAGYNR-AVDCWSLGVI 416
Query: 481 MFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGS 540
+F +C ++ Y F++H SG PE S
Sbjct: 417 LF--IC------------------LSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVS 456
Query: 541 VEASRVCLRLLDPDASTRYTIDDLFNDPWM 570
+A + +LL D R+T ++ PW+
Sbjct: 457 EKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 61.6 bits (148), Expect = 5e-09
Identities = 61/231 (26%), Positives = 102/231 (43%), Gaps = 37/231 (16%)
Query: 263 RKTLGEGGSSQVMT-VHSIYRKKQVYALKRFKL-----FKDETPDHFYHRCITEFMIAKK 316
++ LG G SS V +H Q YA+K + F E + E I +K
Sbjct: 23 KEILGRGVSSVVRRCIHK--PTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRK 80
Query: 317 VSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCC 374
VS H NII+ +T ++ FL+ ++ ++F Y T ++ K
Sbjct: 81 VSGHPNIIQLKDTYET--------NTFFFLVFDLMKRGELFDYLTEKVTLSEKETRK--I 130
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
+ + I +H L I HRD+K EN+L+ D +KLTDFG S +P + ++R
Sbjct: 131 MRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQ--LEPGE------RLR 182
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
CG+P ++ PE++ S ++D W+ G++M+ L+
Sbjct: 183 EVCGTPSYLAPEIIECSMNEDHPGYGK---------EVDMWSTGVIMYTLL 224
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 61.6 bits (148), Expect = 5e-09
Identities = 44/178 (24%), Positives = 81/178 (44%), Gaps = 34/178 (19%)
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQ 377
H +II+ + ++ TPS F++ + V ++F Y G ++ F+Q
Sbjct: 82 HPHIIRLYQVISTPSD--------IFMIMEHVSGGELFDYIVKHGRLKTAEARRF--FQQ 131
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I G+ + H + HRD+K EN+L+ + +K+ DFG+S ++ +R C
Sbjct: 132 IISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNI--------MTDGDFLRTSC 183
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
GSP + PEV+ Y ++D W+ G++++ L+C F + H
Sbjct: 184 GSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILYALLCGTLPFDDEH 227
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 61.6 bits (148), Expect = 5e-09
Identities = 65/244 (26%), Positives = 106/244 (42%), Gaps = 45/244 (18%)
Query: 265 TLGEGGSSQVMTVHSIYRK--KQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
+LG+GG +V+ Y+K + V A+K+ F RC + + N V
Sbjct: 175 SLGKGGFGKVLLG---YKKSDRSVVAIKQLNT-------QFSTRCSRAIAKTRDIRNEVE 224
Query: 323 IIKTFYIMKTPSVSNG---PKRSWAFLMQQCVQDMFHYTTLSGWATKPLDE---KWCCFK 376
++K ++ + K S+ + + F S + L E K+ F
Sbjct: 225 VMKKLSHPNIVAIYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYNRMGLGESLGKYFAF- 283
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYG---ALKLTDFGISTYGIKDPEDPTSERIKI 433
Q+ I ++HS+GI HRDIK EN+L +D LKLTDFG++ + R+K
Sbjct: 284 QLIDAILYLHSVGICHRDIKPENILCSDKAERCILKLTDFGMAKNSV--------NRMKT 335
Query: 434 RGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAE 493
R CG+P + PE++ Y P K+D W+LG ++F + F+E
Sbjct: 336 R--CGTPSYNAPEIV------------ANEGVEYTP-KVDIWSLGCVLFITFSGYPPFSE 380
Query: 494 AHKD 497
+ D
Sbjct: 381 EYTD 384
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 61.6 bits (148), Expect = 5e-09
Identities = 44/178 (24%), Positives = 81/178 (44%), Gaps = 34/178 (19%)
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQ 377
H +II+ + ++ TPS F++ + V ++F Y G ++ F+Q
Sbjct: 82 HPHIIRLYQVISTPSD--------IFMIMEHVSGGELFDYIVKHGRLKTAEARRF--FQQ 131
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I G+ + H + HRD+K EN+L+ + +K+ DFG+S ++ +R C
Sbjct: 132 IISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNI--------MTDGDFLRTSC 183
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
GSP + PEV+ Y ++D W+ G++++ L+C F + H
Sbjct: 184 GSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILYALLCGTLPFDDEH 227
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 61.6 bits (148), Expect = 5e-09
Identities = 48/187 (25%), Positives = 90/187 (47%), Gaps = 15/187 (8%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
++ +G G S+V + R K V ALKR + + + +CI +I + +H N
Sbjct: 106 QEQIGGGTFSKVFKARDLLRNKTV-ALKRIRFDINNSESI---KCIAREIIILRKLDHPN 161
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
+IK +M S+ + + + D+ ++L G K C +Q+ RG+
Sbjct: 162 VIKLEGLMLVDHDSS----TLYLIFEYMEHDLLGLSSLLGVHFSEPQVK-CYMRQLLRGL 216
Query: 383 RHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
H H+ + HRD+K N+L+ G LK+ DFG++T+ DP + + + + + +
Sbjct: 217 DHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLATF--FDPHN----SVPLTTHVATLWY 270
Query: 443 VPPEVMI 449
PPE+++
Sbjct: 271 RPPELLL 277
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 61.2 bits (147), Expect = 6e-09
Identities = 60/239 (25%), Positives = 103/239 (42%), Gaps = 40/239 (16%)
Query: 264 KTLGEGGSSQVMTVHSI--YRKKQVYALKRFK----LFKDETPDHFYHRCITEFMIAKKV 317
K LG G +V V I + ++YA+K K + K +T +H TE + + +
Sbjct: 53 KVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTR----TERQVLEHI 108
Query: 318 SNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQ 377
++ Y +T + + L+ + +T LS E +
Sbjct: 109 RQSPFLVTLHYAFQTETKLH--------LILDYINGGELFTHLSQRERFTEHEVQIYVGE 160
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I + H+H LGI +RDIKLEN+L+ G + LTDFG+S + D E + +C
Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVAD------ETERAYSFC 214
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV---CPFALFAE 493
G+ ++ P+++ +D +D W+LG+LM+ L+ PF + E
Sbjct: 215 GTIEYMAPDIV------------RGGDSGHDK-AVDWWSLGVLMYELLTGASPFTVDGE 260
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 61.2 bits (147), Expect = 6e-09
Identities = 68/250 (27%), Positives = 109/250 (43%), Gaps = 56/250 (22%)
Query: 266 LGEGGSSQVMTVHSIYRKKQV-----YALKRFKLFKDETPDHFYHRCITEFMIAKKVSNH 320
LG G +S V YR KQ YALK K +T D R TE + ++S H
Sbjct: 52 LGRGATSIV------YRCKQKGTQKPYALKVLK----KTVDKKIVR--TEIGVLLRLS-H 98
Query: 321 VNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQI 378
NIIK I +TP+ + L+ + V ++F G+ ++ + KQI
Sbjct: 99 PNIIKLKEIFETPTEIS--------LVLELVTGGELFDRIVEKGYYSER--DAADAVKQI 148
Query: 379 ARGIRHMHSLGIAHRDIKLENVLV---TDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+ ++H GI HRD+K EN+L LK+ DFG+S ++ ++
Sbjct: 149 LEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKI--------VEHQVLMKT 200
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
CG+P + PE++ Y P ++D W++GI+ + L+C F F +
Sbjct: 201 VCGTPGYCAPEIL--------------RGCAYGP-EVDMWSVGIITYILLCGFEPFYDER 245
Query: 496 KDDSKYRHYI 505
D +R +
Sbjct: 246 GDQFMFRRIL 255
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 61.2 bits (147), Expect = 6e-09
Identities = 31/110 (28%), Positives = 58/110 (52%), Gaps = 22/110 (20%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+I + ++HS + +RDIKLEN+++ G +K+TDFG+ GI S+ ++ +
Sbjct: 258 EIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI-------SDGATMKTF 310
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
CG+P ++ PEV+ + +D W LG++M+ ++C
Sbjct: 311 CGTPEYLAPEVLEDNDYGRA---------------VDWWGLGVVMYEMMC 345
>Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 505
Score = 61.2 bits (147), Expect = 6e-09
Identities = 64/273 (23%), Positives = 107/273 (38%), Gaps = 62/273 (22%)
Query: 306 RCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHY-TTLSGWA 364
R E I KK+ +HVN++K ++ P+ N V D+ +
Sbjct: 195 RVYQEIAILKKL-DHVNVVKLIEVLDDPAEDN----------LYLVFDLLRKGPVMEVPC 243
Query: 365 TKPLDEKWC--CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKD 422
KP E+ + + G+ ++H I HRDIK N+L+ D G +K+ DFG+S
Sbjct: 244 DKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVS------ 297
Query: 423 PEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMF 482
++ G+P + PE + + +D WA G+ ++
Sbjct: 298 -NQFEGNDAQLSSTAGTPAFMAPEAI------------SDSGQSFSGKALDVWATGVTLY 344
Query: 483 NLV---CPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLG 539
V CPF DD +A + + +P V+ E PE S+
Sbjct: 345 CFVYGKCPFI-------DD----FILALHRKIK------NEPVVF-----PEEPEISE-- 380
Query: 540 SVEASRVCLRLLDPDASTRYTIDDLFNDPWMAK 572
E + L++LD + TR + D+ PW+ K
Sbjct: 381 --ELKDLILKMLDKNPETRIGVPDIKLHPWVTK 411
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 61.2 bits (147), Expect = 6e-09
Identities = 57/232 (24%), Positives = 102/232 (43%), Gaps = 32/232 (13%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+GEG V + + +V A+K+ F+ +T F R + E I + H NII
Sbjct: 102 IGEGAYGMVASALDTITRDRV-AIKKISPFEHQT---FCQRTLREIKILNRFK-HENIIN 156
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIR 383
I+++ +V + + QC+ + Y L T+ L C+ QI RG++
Sbjct: 157 IQEIIRSETVDSLKD----IYIVQCLMETDLYKLLK---TQKLSNDHVCYFLYQILRGLK 209
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
++HS + HRD+K N+L+ LK+ DFG++ + DP+ T + Y + +
Sbjct: 210 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR--VTDPQ--TDHTGFLTEYVATRWYR 265
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
PE+M+ S +D W++G ++ ++ LF H
Sbjct: 266 APEIMLNSKGYTK--------------SIDVWSVGCILAEMLSNRPLFPGKH 303
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 61.2 bits (147), Expect = 6e-09
Identities = 57/232 (24%), Positives = 102/232 (43%), Gaps = 32/232 (13%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+GEG V + + +V A+K+ F+ +T F R + E I + H NII
Sbjct: 34 IGEGAYGMVASALDTITRDRV-AIKKISPFEHQT---FCQRTLREIKILNRFK-HENIIN 88
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIR 383
I+++ +V + + QC+ + Y L T+ L C+ QI RG++
Sbjct: 89 IQEIIRSETVDSLKD----IYIVQCLMETDLYKLLK---TQKLSNDHVCYFLYQILRGLK 141
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
++HS + HRD+K N+L+ LK+ DFG++ + DP+ T + Y + +
Sbjct: 142 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR--VTDPQ--TDHTGFLTEYVATRWYR 197
Query: 444 PPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
PE+M+ S +D W++G ++ ++ LF H
Sbjct: 198 APEIMLNSKGYTK--------------SIDVWSVGCILAEMLSNRPLFPGKH 235
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 61.2 bits (147), Expect = 6e-09
Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 32/161 (19%)
Query: 358 TTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST 417
T L P D F + + ++HS GI HRD+K +N+L+T G +KLTDFG+S
Sbjct: 922 TLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSK 981
Query: 418 YGIKDPE--------DPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDP 469
G+ D + + + G+P ++ PEV++
Sbjct: 982 MGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGK-------------- 1027
Query: 470 FKMDTWALGILMFNLV---CPF------ALFAEAHKDDSKY 501
+D W++GI+++ + PF LFA DD ++
Sbjct: 1028 -PVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEW 1067
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 60.8 bits (146), Expect = 8e-09
Identities = 54/233 (23%), Positives = 87/233 (37%), Gaps = 78/233 (33%)
Query: 369 DEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLV----------TDYG---------ALK 409
DE FKQ+ G++++H I HRDIK EN+L+ G +K
Sbjct: 303 DESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVK 362
Query: 410 LTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDP 469
+ DFG++ + T E CG+P +V PEV+
Sbjct: 363 IADFGLAKF--------TGEMQFTNTLCGTPSYVAPEVLTKKGYTS-------------- 400
Query: 470 FKMDTWALGILMFNLVCPFALFAEAHKDDS--------KYRHYIAFYEQFNKHSPHFRKP 521
K+D W+ G++++ +C F F++ S KY Y ++++ + H
Sbjct: 401 -KVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISN 459
Query: 522 GVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMAKIE 574
L +L+PD RY ID+ N PW I+
Sbjct: 460 --------------------------LLVLNPD--ERYNIDEALNHPWFNDIQ 484
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 60.8 bits (146), Expect = 8e-09
Identities = 58/237 (24%), Positives = 99/237 (41%), Gaps = 41/237 (17%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
KT+G+G ++V I ++V A+K K + + E I K + NH NI
Sbjct: 60 KTIGKGNFAKVKLARHILTGREV-AIKIID--KTQLNPTSLQKLFREVRIMK-ILNHPNI 115
Query: 324 IKTFYIMKTPSV--------SNGPKRSWAF----LMQQCVQDMFHYTTLSGWATK---PL 368
+K F +++T S G + + ++ + F +G K
Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSF 175
Query: 369 DEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTS 428
D F I +++ H I HRD+K EN+L+ +K+ DFG S + +
Sbjct: 176 DLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFS--------NEFT 227
Query: 429 ERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
K+ +CGSPP+ PE+ YD ++D W+LG++++ LV
Sbjct: 228 VGGKLDTFCGSPPYAAPELF--------------QGKKYDGPEVDVWSLGVILYTLV 270
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 60.8 bits (146), Expect = 8e-09
Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 22/109 (20%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
++A I ++HSL I +RD+K EN+L+ G + LTDFG+ G+ +PED TS +
Sbjct: 202 EVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGV-EPEDTTST------F 254
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
CG+P ++ PEV+ YD +D W LG +++ ++
Sbjct: 255 CGTPEYLAPEVL--------------RKEPYDR-AVDWWCLGAVLYEML 288
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 60.8 bits (146), Expect = 8e-09
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 35/182 (19%)
Query: 276 TVHSIYRKKQVYA--LKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTF--YIMK 331
T +Y+ + V+ L K+ K E D F I + + K H NI+ F Y+ +
Sbjct: 30 TYGDVYKARNVHTGELAAVKIIKLEPGDDF--SLIQQEIFMVKECKHCNIVAYFGSYLSR 87
Query: 332 TPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIRHM 385
++ W M+ C +QD++H T PL E + ++ +G+ ++
Sbjct: 88 --------EKLW-ICMEYCGGGSLQDIYH-------VTGPLSELQIAYVCRETLQGLAYL 131
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPP 445
H+ G HRDIK N+L+TD+G +KL DFG++ T+ K + + G+P + P
Sbjct: 132 HTKGKMHRDIKGANILLTDHGDVKLADFGVAA-------KITATIAKRKSFIGTPYWMAP 184
Query: 446 EV 447
EV
Sbjct: 185 EV 186
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 60.8 bits (146), Expect = 8e-09
Identities = 72/315 (22%), Positives = 125/315 (38%), Gaps = 72/315 (22%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFK---LFKDETPDHFYHRCITEFMIAKKVSNH 320
+ LG G S+V V K ++ALK K F+D + ++ E + KK+ H
Sbjct: 27 EVLGSGAFSEVFLVKQRLTGK-LFALKCIKKSPAFRDSSLEN-------EIAVLKKIK-H 77
Query: 321 VNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQI 378
NI+ I ++ + +L+ Q V ++F G T+ + +Q+
Sbjct: 78 ENIVTLEDIYESTT--------HYYLVMQLVSGGELFDRILERGVYTEK--DASLVIQQV 127
Query: 379 ARGIRHMHSLGIAHRDIKLENVLV---TDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
++++H GI HRD+K EN+L + + +TDFG+S + +
Sbjct: 128 LSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLS---------KMEQNGIMST 178
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
CG+P +V PEV+ +D W++G++ + L+C
Sbjct: 179 ACGTPGYVAPEVLAQKPYSKA---------------VDCWSIGVITYILLC--------- 214
Query: 496 KDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDA 555
Y FYE+ K G Y E P + + +C LL+ D
Sbjct: 215 -------GYPPFYEETESKLFEKIKEGYYE----FESPFWDDISESAKDFIC-HLLEKDP 262
Query: 556 STRYTIDDLFNDPWM 570
+ RYT + + PW+
Sbjct: 263 NERYTCEKALSHPWI 277
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 60.8 bits (146), Expect = 8e-09
Identities = 64/263 (24%), Positives = 113/263 (42%), Gaps = 49/263 (18%)
Query: 266 LGEGGSSQVMTVHSIYRK--KQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
LG+GG +V+ Y+K + V A+K+ F RC + + N V +
Sbjct: 175 LGKGGFGKVLLG---YKKSDRSVVAIKQLNT-------QFSTRCSRAIAKTRDIQNEVEV 224
Query: 324 IKTFY---IMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDE---KWCCFKQ 377
+K I+ K S+ + + F S + L E K+ F Q
Sbjct: 225 MKKLSHPNIVAIYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKYFAF-Q 283
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYG---ALKLTDFGISTYGIKDPEDPTSERIKIR 434
+ + ++HS+GI HRDIK EN+L ++ LKLTDFG++ + +++
Sbjct: 284 LIDAVLYLHSVGICHRDIKPENILCSNKAERCILKLTDFGMAKNSVN----------RMK 333
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
+CG+P + PE++ Y P K+D W+LG ++F + F+E
Sbjct: 334 THCGTPSYCAPEIV------------ANQGVEYTP-KVDIWSLGCVLFITFSGYPPFSEE 380
Query: 495 H----KDDSKYRHYIAFYEQFNK 513
+ D+ + F+EQ+++
Sbjct: 381 YTDLKMDEQVLTGRLFFHEQWHR 403
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 60.8 bits (146), Expect = 8e-09
Identities = 35/111 (31%), Positives = 61/111 (54%), Gaps = 26/111 (23%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+IA G+ +HS GI +RD+KL+NV++ G +K+TDFG+ I D T+ + +
Sbjct: 520 EIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFG--DATT-----KTF 572
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPF--KMDTWALGILMFNLV 485
CG+P ++ PE+++ Y P+ +D WA G+L+F ++
Sbjct: 573 CGTPDYIAPEIIL-----------------YQPYGKSVDWWAYGVLLFEML 606
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 60.5 bits (145), Expect = 1e-08
Identities = 57/227 (25%), Positives = 101/227 (44%), Gaps = 39/227 (17%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
+KT+G G +V V +I ++ ALK + T R E ++ + + H N
Sbjct: 56 KKTIGAGSMGKVKLVVNILTGEKA-ALKMIPFTPNNTSQTV--RVQREALLGRLL-RHPN 111
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQIAR 380
I + ++TP+ + +++ + V + Y G + L + Q+
Sbjct: 112 ICRVIDCIRTPACT--------YILFEYVPGGQLLEYILARGKLDEDLARSFAM--QLIN 161
Query: 381 GIRHMHSLGIAHRDIKLENVLVT-DYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ ++H I HRD+K+ENVL+T D +KL DFG+S + KD +R YCGS
Sbjct: 162 ALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDD--------LLRTYCGS 213
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
PE++ Y ++D W+LG++++ +VC
Sbjct: 214 LYFAAPELL--------------DAKPYIGPEVDVWSLGVVIYVMVC 246
>SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase
Length = 470
Score = 60.5 bits (145), Expect = 1e-08
Identities = 65/247 (26%), Positives = 94/247 (37%), Gaps = 23/247 (9%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G G V IY +YA+K L KD + E + +VS+H II
Sbjct: 24 IGAGAYGVVYKAEDIY-DGTLYAVKA--LCKDGLNEKQKKLQARELALHARVSSHPYIIT 80
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCFKQIARGIRH 384
+++T ++Q C D+F Y T F Q+ + H
Sbjct: 81 LHRVLETEDAIY-------VVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEH 133
Query: 385 MHSLGIAHRDIKLENVLV-TDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
HS+GI HRD+K EN++V D + L DFG++T +P S P
Sbjct: 134 CHSVGIYHRDLKPENIMVGNDVNTVYLADFGLAT------TEPYSSDFGCGSLFYMSPEC 187
Query: 444 PPEVMILSXXXXXXXXX----XXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA-HKDD 498
EV LS + D WALGI++ NL C + A + D
Sbjct: 188 QREVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWKRACSQTD 247
Query: 499 SKYRHYI 505
YR Y+
Sbjct: 248 GTYRSYV 254
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 60.5 bits (145), Expect = 1e-08
Identities = 47/182 (25%), Positives = 82/182 (44%), Gaps = 34/182 (18%)
Query: 316 KVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWC 373
K+ H +IIK + ++ TP+ F++ + V ++F Y G + E
Sbjct: 69 KLFRHPHIIKLYQVISTPTDF--------FMVMEYVSGGELFDYICKHGRVEEM--EARR 118
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKI 433
F+QI + + H + HRD+K ENVL+ + K+ DFG+S + S+ +
Sbjct: 119 LFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS--------NMMSDGEFL 170
Query: 434 RGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAE 493
R CGSP + PEV+ Y ++D W+ G++++ L+C F +
Sbjct: 171 RTSCGSPNYTAPEVI--------------SGRLYAGPEVDIWSCGVILYALLCGTLPFDD 216
Query: 494 AH 495
H
Sbjct: 217 EH 218
>Hs4505811 [T] KOG0583 Serine/threonine protein kinase
Length = 313
Score = 60.5 bits (145), Expect = 1e-08
Identities = 58/224 (25%), Positives = 88/224 (38%), Gaps = 57/224 (25%)
Query: 351 VQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLV-TDYGALK 409
VQD+F + T G + L + F Q+ +RH H+ G+ HRDIK EN+L+ + G LK
Sbjct: 126 VQDLFDFITERGALQEELARSF--FWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELK 183
Query: 410 LTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDP 469
L DFG +KD + G+ + PPE + Y
Sbjct: 184 LIDFGSGAL-LKD--------TVYTDFDGTRVYSPPEWI--------------RYHRYHG 220
Query: 470 FKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPG 529
W+LGIL++++VC F D+ R + F ++ + H
Sbjct: 221 RSAAVWSLGILLYDMVCGDIPF---EHDEEIIRGQVFFRQRVSSECQHL----------- 266
Query: 530 AEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWMAKI 573
R CL L D R T +++ N PWM +
Sbjct: 267 --------------IRWCLALRPSD---RPTFEEIQNHPWMQDV 293
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 60.5 bits (145), Expect = 1e-08
Identities = 59/242 (24%), Positives = 109/242 (44%), Gaps = 42/242 (17%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G G S+V+ V KK +A+K + + E + C++E + ++VS+
Sbjct: 69 IGTGSFSRVVRVEQKTTKKP-FAIKVMETREREGRE----ACVSELSVLRRVSHR----- 118
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHM 385
YI++ + + + + ++F G T+ + + +A GIR++
Sbjct: 119 --YIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTER--DAVRILQMVADGIRYL 174
Query: 386 HSLGIAHRDIKLENVLVTDYG---ALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
H+L I HR++K EN+L G + +TDFG++ Y K D T + + CG+P +
Sbjct: 175 HALQITHRNLKPENLLYYHPGEESKILITDFGLA-YSGKKSGDWTMKTL-----CGTPEY 228
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYR 502
+ PEV++ +D WALG++ + L+ F F D+S+ R
Sbjct: 229 IAPEVLLRKPYTSA---------------VDMWALGVITYALLSGFLPF----DDESQTR 269
Query: 503 HY 504
Y
Sbjct: 270 LY 271
>CE26076 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 503
Score = 60.5 bits (145), Expect = 1e-08
Identities = 68/308 (22%), Positives = 127/308 (41%), Gaps = 52/308 (16%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVS--NHV 321
+TLGEG +V+ + + + A+K+ + +++ D F E+++ K+VS H
Sbjct: 28 QTLGEGAFGEVLLIVNTKNPEVAAAMKKINI-ANKSKD-FIDNIRKEYLLQKRVSAVGHD 85
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
N+I+ + N P+ + FL ++F + + + FKQ+ G
Sbjct: 86 NVIRMI------GMRNDPQFYYLFLEYADGGELFDKIEPDCGMSPVFAQFY--FKQLICG 137
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
++ +H + HRDIK EN+L+T LK++DFG++T E ER+ + CG+ P
Sbjct: 138 LKFIHDNDVVHRDIKPENLLLTGTHVLKISDFGMATLYRNKGE----ERL-LDLSCGTIP 192
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKY 501
+ PE+ Y +D W+ GI++ ++ + A Y
Sbjct: 193 YAAPELC--------------AGKKYRGPPVDVWSSGIVLIAMLTGELPWDRASDASQSY 238
Query: 502 RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTI 561
+I S + + K+ V A + +++ R TI
Sbjct: 239 MGWI--------------------SNTSLDERPWKKI-DVRALCMLRKIVTDKTDKRATI 277
Query: 562 DDLFNDPW 569
+ + DPW
Sbjct: 278 EQIQADPW 285
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 60.5 bits (145), Expect = 1e-08
Identities = 33/109 (30%), Positives = 61/109 (55%), Gaps = 23/109 (21%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
Q+A G++H+H+L I HRD+KL N+ + ++ +K+ DFG++T+ K +E+ RG
Sbjct: 141 QVAEGVKHLHNLQIIHRDLKLGNLFLNEHLQVKIGDFGLATFCEK------NEKKMTRG- 193
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
G+P ++ PEV+ F++D WA+G +++ L+
Sbjct: 194 -GTPNYIAPEVL---------------NETGHAFEVDIWAIGCILYVLL 226
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 60.5 bits (145), Expect = 1e-08
Identities = 51/186 (27%), Positives = 89/186 (47%), Gaps = 20/186 (10%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G+G S V + K + ALKR + + D + + +I + +H N++K
Sbjct: 143 IGQGTYSSVYKARDLTNNK-IVALKRVRF---DLSDLESVKFMAREIIVMRRLDHPNVLK 198
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHM 385
++ T SVS+ S + + D+ ++ G K C +Q+ G+ H
Sbjct: 199 LEGLI-TASVSS----SLYLVFEYMDHDLVGLASIPGIKFSEPQVK-CYMQQLLSGLHHC 252
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPED--PTSERIKIRGYCGSPPHV 443
HS G+ HRDIK N+L+ G LK+ DFG++T+ DP++ P + R+ Y
Sbjct: 253 HSRGVLHRDIKGSNLLIDSNGVLKIADFGLATF--FDPQNCVPLTSRVVTLWY------R 304
Query: 444 PPEVMI 449
PPE+++
Sbjct: 305 PPELLL 310
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 60.5 bits (145), Expect = 1e-08
Identities = 49/186 (26%), Positives = 92/186 (49%), Gaps = 20/186 (10%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKL-FKDETPDHFYHRCITEFMIAKKVSNHVNII 324
+G+G S V + K + ALK+ + D F R E ++ +++ +H N++
Sbjct: 219 IGQGTYSSVYRARDLLHNK-IVALKKVRFDLNDMESVKFMAR---EIIVMRRL-DHPNVL 273
Query: 325 KTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWA-TKPLDEKWCCFKQIARGIR 383
K ++ P S S + + D+ ++L G T+P + C +Q+ G+
Sbjct: 274 KLEGLITAPVSS-----SLYLVFEYMDHDLLGLSSLPGVKFTEP--QVKCYMRQLLSGLE 326
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHV 443
H HS G+ HRDIK N+L+ G LK+ DFG++T+ DP ++ + + + + +
Sbjct: 327 HCHSRGVLHRDIKGSNLLIDSKGVLKIADFGLATF--FDP----AKSVSLTSHVVTLWYR 380
Query: 444 PPEVMI 449
PPE+++
Sbjct: 381 PPELLL 386
>7299507 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 1142
Score = 60.5 bits (145), Expect = 1e-08
Identities = 83/330 (25%), Positives = 131/330 (39%), Gaps = 67/330 (20%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
LGEG + V T +IY + YA+K D+ P H R E H+ I++
Sbjct: 124 LGEGAYASVQTCVNIYTDLE-YAVKVI----DKIPGHARARVFREVETFHHCQGHLGILQ 178
Query: 326 T---------FYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFK 376
FY++ ++ GP S +Q+ ++ E K
Sbjct: 179 LIEFFEDDEKFYLV-FEKINGGPLLSR-------IQEHICFSE---------HEASQIIK 221
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGAL---KLTDFGISTYGIKDPEDPTSERI-- 431
+IA G+ +H GIAHRD+K EN+L +L K+ DF + + GIK D +S
Sbjct: 222 EIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGS-GIKFTTDISSPAATP 280
Query: 432 KIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALF 491
++ GS + PEV+ L Y + D W+LG++ + L+C + F
Sbjct: 281 QLLTPVGSAEFMAPEVVDL----------FVGEAHYYDKRCDLWSLGVIAYILLCGYPPF 330
Query: 492 AEAHKDDSKYRH-------YIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEAS 544
+ +D + +E + HF S P AE + S EA
Sbjct: 331 SGNCGEDCGWNRGENCRTCQELLFESIQE--GHF-------SFPEAEWHDVSD----EAK 377
Query: 545 RVCLRLLDPDASTRYTIDDLFNDPWMAKIE 574
+ LL AS R + + + N PW+ E
Sbjct: 378 DLISNLLVKKASNRLSAEAVLNHPWIRMCE 407
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 60.1 bits (144), Expect = 1e-08
Identities = 43/126 (34%), Positives = 60/126 (47%), Gaps = 23/126 (18%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
QIA + +MH I HRDIK EN+L+ +KLTDFG S I PE+ + +
Sbjct: 210 QIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSI--INPPEN------RRKTV 261
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHK 496
CG+ ++ PE++ YD +D WALG+L F L+ F E K
Sbjct: 262 CGTIDYLSPEMV--------------ESREYD-HTIDAWALGVLAFELLTGAPPFEEEMK 306
Query: 497 DDSKYR 502
D + R
Sbjct: 307 DTTYKR 312
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 60.1 bits (144), Expect = 1e-08
Identities = 51/203 (25%), Positives = 90/203 (44%), Gaps = 50/203 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI + H H +G+ HRD+K EN+L+ A+KL DFG++ + E+
Sbjct: 115 CIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAI-------EVEGEQ 167
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPF--KMDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 168 QAWFGFAGTPGYLSPEVL-----------------RKDPYGKPVDLWACGVILYILLVGY 210
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y+Q K G Y PE+ + + EA +
Sbjct: 211 PPF----WDEDQHR----LYQQI--------KAGAY----DFPSPEWDTV-TPEAKDLIN 249
Query: 549 RLLDPDASTRYTIDDLFNDPWMA 571
++L + S R T + PW++
Sbjct: 250 KMLTINPSKRITAAEALKHPWIS 272
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 60.1 bits (144), Expect = 1e-08
Identities = 36/126 (28%), Positives = 62/126 (48%), Gaps = 31/126 (24%)
Query: 370 EKWCCF--KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPT 427
E CF Q+ ++++HSL + HRD+K EN+L+ G L++TDFG
Sbjct: 141 EPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGF------------ 188
Query: 428 SERIKIRGY--CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++R+K R + CG+P ++ PE+++ +D WALG+L++ +
Sbjct: 189 AKRVKGRTWTLCGTPEYLAPEIILSKGYNKA---------------VDWWALGVLIYEMA 233
Query: 486 CPFALF 491
F F
Sbjct: 234 VGFPPF 239
>CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 829
Score = 60.1 bits (144), Expect = 1e-08
Identities = 58/219 (26%), Positives = 96/219 (43%), Gaps = 47/219 (21%)
Query: 276 TVHSIYRKKQVYA--LKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTF--YIMK 331
T +Y+ + + + L K+ K E D+F I + ++ + +H NII F YI +
Sbjct: 25 TYGEVYKARDIRSDSLAAVKVVKLEAGDNF--AVIQQEIMVIRECSHPNIIAYFGSYIRR 82
Query: 332 TPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIRHM 385
R W +M+ C +QD++H T PL E F ++ RG+ ++
Sbjct: 83 D--------RLW-IVMEYCGGGSLQDIYHLTG-------PLSELQIAFVCRETLRGLNYL 126
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPP 445
H++G HRDIK N+L++ G +KL DFG++ T+ K + + G+P + P
Sbjct: 127 HNMGKIHRDIKGANILLSSSGDVKLADFGVAA-------QITATIGKRKSFIGTPYWMAP 179
Query: 446 EVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
EV + + D WA GI L
Sbjct: 180 EVACVEKRGGYG------------MQCDVWATGITAIEL 206
>CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 357
Score = 60.1 bits (144), Expect = 1e-08
Identities = 47/178 (26%), Positives = 79/178 (43%), Gaps = 30/178 (16%)
Query: 310 EFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLD 369
E I KK+S H N++K ++ + P ++ +++ + V+ + L KPLD
Sbjct: 91 EIAILKKLS-HPNVVKLVEVL------DDPNDNYLYMVFEFVEKG---SILEIPTDKPLD 140
Query: 370 EK--WCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPT 427
E W F+ G+ ++H I HRDIK N+L++D G +K+ DFG+S +
Sbjct: 141 EDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADFGVSC-------EFE 193
Query: 428 SERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+ G G+P + PE + Y D W+LGI ++ V
Sbjct: 194 GIDAFLSGTAGTPAFMAPEAL-----------TEGANHFYSGRAQDIWSLGITLYAFV 240
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 60.1 bits (144), Expect = 1e-08
Identities = 48/196 (24%), Positives = 88/196 (44%), Gaps = 48/196 (24%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+Q+ + + H+ G+ HRD+K +N+L+ G LK++DFG+S P S + +
Sbjct: 115 FQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAV-------PKSGDM-LS 166
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEA 494
CGSP ++ PE+++ Y +D W+ G+++F L
Sbjct: 167 TACGSPCYIAPELIM--------------NKGYSGAAVDVWSCGVILFEL---------- 202
Query: 495 HKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPD 554
+A Y F+ H+ P +Y+ A++ F + E R+ +LDP+
Sbjct: 203 ----------LAGYPPFDDHT----LPVLYKKILRADY-TFPPGFTGEQKRLIFNILDPN 247
Query: 555 ASTRYTIDD-LFNDPW 569
+R T+ + + D W
Sbjct: 248 PLSRITLAEIIIKDSW 263
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 60.1 bits (144), Expect = 1e-08
Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 21/115 (18%)
Query: 373 CCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIK 432
C KQ+ G+ H HS GI HRDIK N+LV + G LK+ DFG++++ D + P + R+
Sbjct: 244 CFMKQLLCGLEHCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPLTSRVV 303
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL-VC 486
Y PE+++ S Y P +D W++G ++ L VC
Sbjct: 304 TLWYRA------PELLLGS-------------TEYGP-AIDLWSVGCILAELFVC 338
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 60.1 bits (144), Expect = 1e-08
Identities = 45/176 (25%), Positives = 77/176 (43%), Gaps = 36/176 (20%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
++ ++ +H+ G+ +RD+KL+N+L+ G KL DFG+ GI + T+ +
Sbjct: 515 EVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTT-------F 567
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC---PF----- 488
CG+P ++ PE++ +D WALG+LM+ ++ PF
Sbjct: 568 CGTPDYIAPEILKEQEYGA---------------SVDWWALGVLMYEMMAGQPPFEADNE 612
Query: 489 -ALFAEAHKDDSKY-----RHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKL 538
LF DD Y R ++ + F +P R +HP F+KL
Sbjct: 613 DELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCTGDENEIRKHPFFAKL 668
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 60.1 bits (144), Expect = 1e-08
Identities = 56/226 (24%), Positives = 97/226 (42%), Gaps = 35/226 (15%)
Query: 263 RKTLGEGGSSQVMTVHSIYRK--KQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNH 320
+K LG+GG +V V + + +A+K K T E I + V H
Sbjct: 80 KKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVK-H 138
Query: 321 VNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF-KQIA 379
I++ Y +T + + L ++F + G L++ C + +I
Sbjct: 139 PFIVELVYAFQTDG------KLYLILEYLSGGELFMHLEREGIF---LEDTTCFYLSEII 189
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ H+H LGI +RD+K EN+L+ G +KLTDFG+ ++ E I +CG+
Sbjct: 190 LALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLC-------KEHIQEGIVTHTFCGT 242
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
++ PE++ S +D W+LG LMF+++
Sbjct: 243 IEYMAPEILTRSGHGKA---------------VDWWSLGALMFDML 273
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 60.1 bits (144), Expect = 1e-08
Identities = 50/197 (25%), Positives = 87/197 (43%), Gaps = 35/197 (17%)
Query: 297 DETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLM-QQCVQ-DM 354
+ P H E I ++V H II + ++ + + FL+ + C + ++
Sbjct: 64 ETNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDA--------FVFLVFELCPKGEL 115
Query: 355 FHYTTLSGWATKPLDEKWC--CFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTD 412
F Y T + L EK +QI G+ ++H+ I HRD+K EN+L+ + +K+TD
Sbjct: 116 FDYLT----SVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITD 171
Query: 413 FGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKM 472
FG + E K+ CG+P ++ PE + + ++
Sbjct: 172 FGFA--------KQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQ---------EV 214
Query: 473 DTWALGILMFNLV--CP 487
D WA G++MF L+ CP
Sbjct: 215 DIWACGVIMFTLLVGCP 231
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 60.1 bits (144), Expect = 1e-08
Identities = 47/169 (27%), Positives = 79/169 (45%), Gaps = 12/169 (7%)
Query: 255 NFAFADSGRK-----TLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCIT 309
+F + D K +G+G +V K+ A+K K+ D + F +
Sbjct: 40 DFPYCDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMK--KVLMDNEKEGFPITALR 97
Query: 310 EFMIAKKVSNHVNIIKTFYIMKTPSVS-NGPKRSWAFLMQQCVQDMFHYTTLSGWATK-P 367
E I + + H N++ I +T + + NG + ++ + C D+ LS K
Sbjct: 98 EIRILQLLK-HENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGL--LSNMNVKFS 154
Query: 368 LDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS 416
L E +Q+ G+ ++HS I HRD+K NVL+T +G LKL DFG++
Sbjct: 155 LGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLA 203
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 59.7 bits (143), Expect = 2e-08
Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 51/235 (21%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G+G S VM SI KK+ YA K E++I +K +V+I K
Sbjct: 185 IGDGAYSTVMLATSIDTKKR-YAAKVLN---------------KEYLIRQKKVKYVSIEK 228
Query: 326 TFY--IMKTPSVSN-----GPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF--K 376
T + +PSV + S FL++ F + + + + LDE +
Sbjct: 229 TALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDF-LSLMKKYGS--LDETCARYYAA 285
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGI------STYGIKDPEDPTSER 430
QI I ++HS GI HRDIK EN+L+ +KLTDFG + + PE S R
Sbjct: 286 QIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTR 345
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
K + G+ +V PE++ + ++ D WA G ++F ++
Sbjct: 346 SK--SFVGTAEYVSPELL---------------NDSFTDYRCDIWAFGCILFQMI 383
>Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 59.7 bits (143), Expect = 2e-08
Identities = 55/223 (24%), Positives = 90/223 (39%), Gaps = 30/223 (13%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K +G GGSS+V V + KKQ+YA+K L +E + E K+ H +
Sbjct: 513 KQIGSGGSSKVFQV--LNEKKQIYAIKYVNL--EEADNQTLDSYRNEIAYLNKLQQHSDK 568
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLD----EKWCCFKQIA 379
I Y + + +++ +C L+ W K E+ +K +
Sbjct: 569 IIRLYDYEITD-------QYIYMVMECGN-----IDLNSWLKKKKSIDPWERKSYWKNML 616
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ +H GI H D+K N L+ D G LKL DFGI+ + P + + G+
Sbjct: 617 EAVHTIHQHGIVHSDLKPANFLIVD-GMLKLIDFGIA-----NQMQPDTTSVVKDSQVGT 670
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMF 482
++PPE + P K D W+LG +++
Sbjct: 671 VNYMPPEAI---KDMSSSRENGKSKSKISP-KSDVWSLGCILY 709
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 59.7 bits (143), Expect = 2e-08
Identities = 42/136 (30%), Positives = 64/136 (46%), Gaps = 28/136 (20%)
Query: 351 VQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIRHMHSLGIAHRDIKLENVLVTDYGAL 408
+Q+++H AT PL+E+ + ++ +G+ H+HS G HRDIK N+L+T G +
Sbjct: 98 LQEIYH-------ATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDV 150
Query: 409 KLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYD 468
KL DFG+S + T+ K R + G+P + PEV +
Sbjct: 151 KLADFGVS-------GELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNEL--------- 194
Query: 469 PFKMDTWALGILMFNL 484
D WALGI L
Sbjct: 195 ---CDVWALGITAIEL 207
>Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 59.7 bits (143), Expect = 2e-08
Identities = 55/223 (24%), Positives = 90/223 (39%), Gaps = 30/223 (13%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
K +G GGSS+V V + KKQ+YA+K L +E + E K+ H +
Sbjct: 513 KQIGSGGSSKVFQV--LNEKKQIYAIKYVNL--EEADNQTLDSYRNEIAYLNKLQQHSDK 568
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLD----EKWCCFKQIA 379
I Y + + +++ +C L+ W K E+ +K +
Sbjct: 569 IIRLYDYEITD-------QYIYMVMECGN-----IDLNSWLKKKKSIDPWERKSYWKNML 616
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ +H GI H D+K N L+ D G LKL DFGI+ + P + + G+
Sbjct: 617 EAVHTIHQHGIVHSDLKPANFLIVD-GMLKLIDFGIA-----NQMQPDTTSVVKDSQVGT 670
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMF 482
++PPE + P K D W+LG +++
Sbjct: 671 VNYMPPEAI---KDMSSSRENGKSKSKISP-KSDVWSLGCILY 709
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 59.7 bits (143), Expect = 2e-08
Identities = 67/287 (23%), Positives = 117/287 (40%), Gaps = 66/287 (22%)
Query: 220 TEGDAKGE---NILPLPLKNPNDFL--------PESMQQPSVMLTDNFAFADSGRKTLGE 268
T G+ GE N+ ++ NDF PE + + + + D+F F K LG+
Sbjct: 133 TNGNPSGESDVNMDATSTRSDNDFESTVMNIDEPEEVPRKNTVTMDDFDFL----KVLGQ 188
Query: 269 GGSSQVMTVHSIYRKKQVYALK---------RFKLFKDETPDHFYHRCITEFMIAKKVSN 319
G +V+ K +YA+K R ++ T + + C+ F+ K S
Sbjct: 189 GTFGKVILCREKSSDK-LYAIKIIRKEMVVDRSEVAHTLTENRVLYACVHPFLTLLKYSF 247
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIA 379
++I +NG + +Q+C T G +I
Sbjct: 248 QAQ----YHICFVMEFANGGELFTH--LQRCKTFSEARTRFYG-------------SEII 288
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ ++H I +RD+KLEN+L+ G +K+TDFG+ IK + K +CG+
Sbjct: 289 LALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGD-------KTSTFCGT 341
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
P ++ PEV+ YD +D W +G++M+ ++C
Sbjct: 342 PEYLAPEVI--------------EDIDYDR-SVDWWGVGVVMYEMMC 373
>CE27410 [T] KOG0583 Serine/threonine protein kinase
Length = 617
Score = 59.7 bits (143), Expect = 2e-08
Identities = 49/220 (22%), Positives = 93/220 (42%), Gaps = 24/220 (10%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G G +V +Y + A+K K K + + +E I +++ NH N+IK
Sbjct: 189 IGTGSYGKVKECIDMYTLTR-RAVKIMKYDKLRKITNGWENIRSEMSILRRM-NHRNVIK 246
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHM 385
I P+ K + + C+ + + + E F ++ +G+ ++
Sbjct: 247 LIEIFNIPA-----KGKVYMVFEYCIGSVQQLLDMEPARRLTIGESHAIFIELCQGLNYL 301
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPP 445
HS ++H+DIK N+LV+ +K+ DFG++ D ++ G+P PP
Sbjct: 302 HSKRVSHKDIKPGNLLVSIDFTVKICDFGVAEQINLFQRDGRCTKVN-----GTPKFQPP 356
Query: 446 EVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
E + +D +K D W+ G+ ++NLV
Sbjct: 357 ECI------------YGNHDFFDGYKADMWSAGVTLYNLV 384
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 59.7 bits (143), Expect = 2e-08
Identities = 67/287 (23%), Positives = 117/287 (40%), Gaps = 66/287 (22%)
Query: 220 TEGDAKGE---NILPLPLKNPNDFL--------PESMQQPSVMLTDNFAFADSGRKTLGE 268
T G+ GE N+ ++ NDF PE + + + + D+F F K LG+
Sbjct: 133 TNGNPSGESDVNMDATSTRSDNDFESTVMNIDEPEEVPRKNTVTMDDFDFL----KVLGQ 188
Query: 269 GGSSQVMTVHSIYRKKQVYALK---------RFKLFKDETPDHFYHRCITEFMIAKKVSN 319
G +V+ K +YA+K R ++ T + + C+ F+ K S
Sbjct: 189 GTFGKVILCREKSSDK-LYAIKIIRKEMVVDRSEVAHTLTENRVLYACVHPFLTLLKYSF 247
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIA 379
++I +NG + +Q+C T G +I
Sbjct: 248 QAQ----YHICFVMEFANGGELFTH--LQRCKTFSEARTRFYG-------------SEII 288
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
+ ++H I +RD+KLEN+L+ G +K+TDFG+ IK + K +CG+
Sbjct: 289 LALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGD-------KTSTFCGT 341
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
P ++ PEV+ YD +D W +G++M+ ++C
Sbjct: 342 PEYLAPEVI--------------EDIDYDR-SVDWWGVGVVMYEMMC 373
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 59.7 bits (143), Expect = 2e-08
Identities = 51/234 (21%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 254 DNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQ--VYALKRFKLFKDETPDHFYHRCITEF 311
+NFA + LG+G +V V + K +YA+K + + T + E
Sbjct: 15 ENFALL----RVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAER 70
Query: 312 MIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEK 371
+ +++ ++ FY +T + + ++ + V+ +T L L+
Sbjct: 71 QVLERLRGTPFLVNLFYAFQTDTKLH--------IVMEYVRGGELFTHLCSRGHFDLEAA 122
Query: 372 WCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERI 431
++ I +H + +RD+KLEN+L+ + G +KLTDFG+S + D
Sbjct: 123 RFVIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGELD------ 176
Query: 432 KIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+ YCG+ ++ PEV+ +D W+LG++ F L+
Sbjct: 177 RANSYCGTIEYMSPEVINRPEGGYSDV-------------VDWWSLGVISFELL 217
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 59.7 bits (143), Expect = 2e-08
Identities = 44/170 (25%), Positives = 84/170 (48%), Gaps = 14/170 (8%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+GEG V R ++ ALK+ ++ D+ D + E MI K+ +H NI++
Sbjct: 59 VGEGSYGIVYRARDT-RSNEIVALKKVRM--DQEKDGLPISGLREIMILKQC-HHENIVR 114
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKW--CCFKQIARGIR 383
++ S+ S +M C QD+ ++ ++P E C Q+ + ++
Sbjct: 115 LREVVVGKSLD-----SIFLVMDFCEQDL---ASVLDNMSQPFTESEVKCITLQVLKALK 166
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKI 433
++HS + HRD+K+ N+L+TD G +K+ DFG++ P+ T + + +
Sbjct: 167 YLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTL 216
>YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 655
Score = 59.3 bits (142), Expect = 2e-08
Identities = 46/168 (27%), Positives = 77/168 (45%), Gaps = 36/168 (21%)
Query: 350 CVQDMFHYTTLS--GWATKPLDEKWCCF--KQIARGIRHMHSLGIAHRDIKLENVLVTDY 405
C+ D+ S G + PL+E + K+ +G++ +H+ I HRDIK +N+L+
Sbjct: 459 CLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQ 518
Query: 406 GALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXX 465
G +K+TDFG + T +R K G+P + PE++
Sbjct: 519 GLVKITDFGFCV-------ELTEKRSKRATMVGTPYWMAPEIV--------------NQK 557
Query: 466 XYDPFKMDTWALGILMFNLV---CPF-------ALFAEAHKDDSKYRH 503
YD K+D W+LGI++ ++ P+ AL+ A+ K RH
Sbjct: 558 GYDE-KVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRH 604
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 59.3 bits (142), Expect = 2e-08
Identities = 62/220 (28%), Positives = 97/220 (43%), Gaps = 31/220 (14%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNI 323
+ +G G QV + + Q+ A+K + +DE + E + KK S+H NI
Sbjct: 29 EVVGNGTYGQVYKGRHV-KTGQLAAIKVMDVTEDEEEE-----IKQEINMLKKYSHHRNI 82
Query: 324 IKTFYIMKTPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCFKQIA 379
+ S + W +M+ C V D+ T G A K + C ++I
Sbjct: 83 ATYYGAFIKKSPPGNDDQLW-LVMEFCGAGSVTDLVKNT--KGNALKEDCIAYIC-REIL 138
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGS 439
RG+ H+H+ + HRDIK +NVL+T+ +KL DFG+S D T R + G+
Sbjct: 139 RGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSA-----QLDRTVGRRNT--FIGT 191
Query: 440 PPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGI 479
P + PEV+ YD ++ D W+LGI
Sbjct: 192 PYWMAPEVIACD---------ENPDATYD-YRSDIWSLGI 221
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 59.3 bits (142), Expect = 2e-08
Identities = 35/144 (24%), Positives = 70/144 (48%), Gaps = 29/144 (20%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+I+ G+ +H GI +RD+KL+NV++ G +K+ DFG+ ++ + + R +
Sbjct: 446 EISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMC-------KEHMMDGVTTRTF 498
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPF--KMDTWALGILMFNLVC---PFALF 491
CG+P ++ PE++ Y P+ +D WA G+L++ ++ PF
Sbjct: 499 CGTPDYIAPEII-----------------AYQPYGKSVDWWAYGVLLYEMLAGQPPFDGE 541
Query: 492 AEAHKDDSKYRHYIAFYEQFNKHS 515
E S H +++ + +K +
Sbjct: 542 DEDELFQSIMEHNVSYPKSLSKEA 565
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 59.3 bits (142), Expect = 2e-08
Identities = 57/233 (24%), Positives = 101/233 (42%), Gaps = 34/233 (14%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+GEG V + + RK +V A+K+ F+ +T + R + E I + H N+I
Sbjct: 48 IGEGAYGMVSSAYDHVRKTRV-AIKKISPFEHQT---YCQRTLREIQILLRF-RHENVIG 102
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIR 383
I++ ++ A VQD+ ++ L C+ QI RG++
Sbjct: 103 IRDILRASTLE-------AMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLK 155
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPE-DPTSERIKIRGYCGSPPH 442
++HS + HRD+K N+L+ LK+ DFG++ I DPE D T + Y + +
Sbjct: 156 YIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR--IADPEHDHTG---FLTEYVATRWY 210
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
PE+M+ S +D W++G ++ ++ +F H
Sbjct: 211 RAPEIMLNSKGYTK--------------SIDIWSVGCILAEMLSNRPIFPGKH 249
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 59.3 bits (142), Expect = 2e-08
Identities = 57/230 (24%), Positives = 104/230 (44%), Gaps = 41/230 (17%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRF--KLFKDETPDHFYHRC---ITEFMIAKKVS 318
K LG G SS+V+ + R + A+K ++ ET D RC + +I V
Sbjct: 62 KQLGTGSSSKVVLGRDV-RSGEKVAIKIIPRRVNGGETGD-MEMRCDQRVFREVIISSVL 119
Query: 319 NHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEK--WCCFK 376
NH +I + + +P+ FL+ + V+ Y + ++ PL EK F+
Sbjct: 120 NHPHIARLKNFLYSPT--------HYFLIFEYVKGRQLYDIII--SSGPLKEKEGQRYFR 169
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
Q+ I ++H + HRD+K+EN+L+ + +KL DFG+S + + + +
Sbjct: 170 QLLSAIDYIHRNSVVHRDLKIENILIDENDNVKLIDFGLSNF--------YDNKTLLNTF 221
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
CGS PE++ Y ++D W+LG++++ ++C
Sbjct: 222 CGSLYFAAPELL--------------QGQRYCGPEIDVWSLGVVLYAILC 257
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 59.3 bits (142), Expect = 2e-08
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 15/109 (13%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+++ +G+ + H G HRDIK N+L+ D G +++ DFG+S + D + ++++
Sbjct: 171 REVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDLSRQKVR-HT 229
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
+ G+P + PEVM YD FK D W+LGIL L
Sbjct: 230 FVGTPCWMAPEVM-------------EQVQGYD-FKADIWSLGILAIEL 264
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 59.3 bits (142), Expect = 2e-08
Identities = 52/234 (22%), Positives = 97/234 (41%), Gaps = 33/234 (14%)
Query: 262 GRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDH------FYHRCITEFMIAK 315
G T G ++ + + R + + R K+ + H R I + +
Sbjct: 3 GSGTGSRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEE 62
Query: 316 KVSNHVNIIKTF---YIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKW 372
KV + I++ F +I++ V P + + ++F Y G + DE
Sbjct: 63 KVRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQE--DEAR 120
Query: 373 CCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIK 432
F+QI G+ + H + HRD+K EN+L+ +K+ DFG+S ++D
Sbjct: 121 NFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNI-MRDGH-------F 172
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
++ CGSP + PEV+ Y ++D W+ G++++ L+C
Sbjct: 173 LKTSCGSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILYALLC 212
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 59.3 bits (142), Expect = 2e-08
Identities = 29/77 (37%), Positives = 45/77 (57%), Gaps = 5/77 (6%)
Query: 360 LSGWATKPL-----DEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFG 414
L+G A+ P+ E C +Q+ G+ H HS G+ HRDIK N+L+ D G LK+ DFG
Sbjct: 203 LAGLASSPVVKFSESEVKCLMRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFG 262
Query: 415 ISTYGIKDPEDPTSERI 431
++T + + P + R+
Sbjct: 263 LATIFDPNHKRPMTSRV 279
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 59.3 bits (142), Expect = 2e-08
Identities = 35/120 (29%), Positives = 60/120 (49%), Gaps = 22/120 (18%)
Query: 367 PLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIST-YGIKDPED 425
P E F Q+ G+ ++H GIAHRD+K EN+L+ ++ +K++DFG++T + K E
Sbjct: 118 PQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKER 177
Query: 426 PTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+R CG+ P+V PEV+ Y D W+ G+++ ++
Sbjct: 178 LLDKR------CGTLPYVAPEVL---------------QKAYHAQPADLWSCGVILVTML 216
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 58.9 bits (141), Expect = 3e-08
Identities = 44/178 (24%), Positives = 76/178 (41%), Gaps = 29/178 (16%)
Query: 316 KVSNHVNIIKTFY---IMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKW 372
K+ +N +K I+K V + L C + + Y + L E
Sbjct: 96 KIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKK----RRLKEMN 151
Query: 373 CC--FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSER 430
C F Q+ G+ ++HS G+ HRD+KLEN+L+ L +TDFG + S
Sbjct: 152 ACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGF-------VNEFCSRN 204
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPF 488
++ CGSP + PE++I Y+ K D W+ G++++ ++ +
Sbjct: 205 ELMKTSCGSPCYAAPELVI-------------SAEPYEARKADIWSCGVILYAILAGY 249
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 445
Score = 58.9 bits (141), Expect = 3e-08
Identities = 76/319 (23%), Positives = 123/319 (37%), Gaps = 61/319 (19%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
++ LG GG S++ Q YA K K T F E I +K+ +H N
Sbjct: 163 QRLLGIGGFSRIYMAMDNNTGGQ-YACKIIDKKKISTKRFFEDH---EMTILRKL-DHPN 217
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQIAR 380
IIK + + F+ ++ V D+F Y T G T P QI +
Sbjct: 218 IIKVNMEYNS--------ETQFFIFEEMVTGGDLFSYLTKLG--TVPEVTTLFIMFQILQ 267
Query: 381 GIRHMHSLGIAHRDIKLENVLVTDYG----ALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
G++++H I HRD+KLEN+L+ + LTDFG++ K ++ +
Sbjct: 268 GLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGK--------RLSTF 319
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHK 496
G+P + PE+ L ++D W+LG++MF L+
Sbjct: 320 VGTPEYTAPEIQRLKGRSQVEKENSSGYGK----EVDLWSLGVIMFLLL----------- 364
Query: 497 DDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAS 556
+ +SP F GV P + + S +A + LL +
Sbjct: 365 ---------------SGNSPSF-ADGVKEKQVDFRDPVWKSV-SRQAKDLISNLLKTNPP 407
Query: 557 TRYTIDDLFNDPWMAKIES 575
R+T+ + PW A+ S
Sbjct: 408 DRFTVKQCLSHPWFARHSS 426
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 58.9 bits (141), Expect = 3e-08
Identities = 42/136 (30%), Positives = 64/136 (46%), Gaps = 28/136 (20%)
Query: 351 VQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIRHMHSLGIAHRDIKLENVLVTDYGAL 408
+Q+++H AT PL+E+ + ++ +G+ H+HS G HRDIK N+L+T G +
Sbjct: 97 LQEIYH-------ATGPLEERQIAYVCRERLKGLHHLHSQGKIHRDIKGANLLLTLQGDV 149
Query: 409 KLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYD 468
KL DFG+S + T+ K R + G+P + PEV +
Sbjct: 150 KLADFGVS-------GELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNEL--------- 193
Query: 469 PFKMDTWALGILMFNL 484
D WALGI L
Sbjct: 194 ---CDVWALGITAIEL 206
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 58.9 bits (141), Expect = 3e-08
Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 22/110 (20%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+I + ++HS I +RD+KLEN+++ G +K+TDFG+ GI D ++ +
Sbjct: 254 EIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITD-------AATMKTF 306
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
CG+P ++ PEV+ + +D W LG++M+ ++C
Sbjct: 307 CGTPEYLAPEVLEDNDYGRA---------------VDWWGLGVVMYEMMC 341
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 58.9 bits (141), Expect = 3e-08
Identities = 83/326 (25%), Positives = 137/326 (41%), Gaps = 71/326 (21%)
Query: 276 TVHSIYRKKQVYA--LKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTF--YIMK 331
T +Y+ + V L K+ K E + F + + +I K H NI+ F Y+ +
Sbjct: 26 TYGDVYKARNVNTGELAAIKVIKLEPGEDF--AVVQQEIIMMKDCKHPNIVAYFGSYLRR 83
Query: 332 TPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIRHM 385
+ W M+ C +QD++H T PL E + ++ +G+ ++
Sbjct: 84 D--------KLW-ICMEFCGGGSLQDIYH-------VTGPLSELQIAYVSRETLQGLYYL 127
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPP 445
HS G HRDIK N+L+TD G +KL DFG+S T+ K + + G+P + P
Sbjct: 128 HSKGKMHRDIKGANILLTDNGHVKLADFGVSA-------QITATIAKRKSFIGTPYWMAP 180
Query: 446 EVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGIL----------MFNLVCPFALF--AE 493
EV + D WA+GI MF+L ALF +
Sbjct: 181 EVAAVERKGGYNQL------------CDLWAVGITAIELAELQPPMFDLHPMRALFLMTK 228
Query: 494 AHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRS---GPGAE----HPEFSK-LGSVEASR 545
++ K + + + F+ HF K + ++ P AE HP ++ L A
Sbjct: 229 SNFQPPKLKDKMKWSNSFH----HFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIE 284
Query: 546 VCLRLLDPDASTRYTIDDLFNDPWMA 571
+ ++ +PD ST + DD +P +A
Sbjct: 285 LLDKVNNPDHSTYHDFDDDDPEPLVA 310
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 58.9 bits (141), Expect = 3e-08
Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 24/122 (19%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
+Q+A + + HS G+ HRDIK EN+L+ LKL DFG S ++ K
Sbjct: 151 RQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSV---------VADHSKRHT 201
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
CG+ ++ PE++ F +D WA+GIL+F ++ +A FA
Sbjct: 202 LCGTMDYLAPEMV---------------SNQPHDFNVDIWAIGILLFEMLVGYAPFANQT 246
Query: 496 KD 497
D
Sbjct: 247 GD 248
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 58.9 bits (141), Expect = 3e-08
Identities = 44/169 (26%), Positives = 80/169 (47%), Gaps = 35/169 (20%)
Query: 320 HVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLDEKWCCFKQ 377
H +II+ + +++TP+ +++ + V+ ++F Y G + DE F+Q
Sbjct: 76 HPHIIRQYEVIETPND--------IYVVMEYVKSGELFDYIVEKGKLQE--DEARHLFQQ 125
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
I G+ + H I HRD+K ENVL+ +K+ DFG+S + + ++ C
Sbjct: 126 IISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLS--------NVMHDGHFLKTSC 177
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
GSP + PEV+ Y P +D W+ G++++ L+C
Sbjct: 178 GSPNYAAPEVI--------------SGKPYGP-DVDIWSCGVILYALLC 211
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 58.9 bits (141), Expect = 3e-08
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 26/174 (14%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G+G S V + K V ALK+ K D E +I +K+ NH NI+K
Sbjct: 111 IGQGTYSSVFRAREVETGKMV-ALKKVKF--DNLQPESIRFMAREILILRKL-NHPNIMK 166
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTT--LSGWATKPLDEKW------CCFKQ 377
I+ + + S+ + +F Y L+G ++ P D ++ C KQ
Sbjct: 167 LEGIVTSRASSS-------------IYLVFEYMEHDLAGLSSNP-DIRFTEPQIKCYMKQ 212
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERI 431
+ G+ H H G+ HRDIK N+LV + G LKL DFG++ ++ + R+
Sbjct: 213 LLWGLEHCHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSRV 266
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 58.9 bits (141), Expect = 3e-08
Identities = 54/200 (27%), Positives = 90/200 (45%), Gaps = 32/200 (16%)
Query: 259 ADSGRKT--LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKK 316
ADS K +G+G S V + +KK + ALK+ + D E I ++
Sbjct: 131 ADSFEKLDKIGQGTYSNVYRARDLDQKK-IVALKKVRF--DNLEPESVRFMAREIQILRR 187
Query: 317 VSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTT--LSGWATKPL-----D 369
+ +H NIIK ++ + M + +F Y L+G A+ P
Sbjct: 188 L-DHPNIIKLEGLVTSR-------------MSCSLYLVFEYMEHDLAGLASHPAIKFSES 233
Query: 370 EKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSE 429
+ C +Q+ G+ H HS G+ HRDIK N+L+ + G LK+ DFG++++ P +
Sbjct: 234 QVKCYLQQLLHGLDHCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQTQPLTS 293
Query: 430 RIKIRGYCGSPPHVPPEVMI 449
R+ Y PPE+++
Sbjct: 294 RVVTLWY------RPPELLL 307
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 58.9 bits (141), Expect = 3e-08
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 35/182 (19%)
Query: 276 TVHSIYRKKQVYA--LKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTF--YIMK 331
T +Y+ K++ + L K+ K E D + I + +I + H NII + Y+ +
Sbjct: 36 TYGDVYKAKRIQSNELAAIKVIKLEPSDDI--QIIQQEIIMMRDCRHPNIIAYYGSYLRR 93
Query: 332 TPSVSNGPKRSWAFLMQQC----VQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIRHM 385
+ W M+ C +QD++ T PL E + ++ +G+ ++
Sbjct: 94 D--------KLW-ICMEFCGGGSLQDIYQ-------VTGPLTEVQIAYMCRETLKGLEYL 137
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPP 445
HS+G HRDIK N+L+T+YG +KL DFG+S T+ K + + G+P + P
Sbjct: 138 HSMGKMHRDIKGANILLTEYGDVKLADFGVSA-------QITATINKRKSFIGTPYWMAP 190
Query: 446 EV 447
EV
Sbjct: 191 EV 192
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 58.9 bits (141), Expect = 3e-08
Identities = 75/324 (23%), Positives = 141/324 (43%), Gaps = 44/324 (13%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRC-ITEFMIAKKVSNHV 321
++ LG G V KQV K ++FK+++ +C + E I +++S H
Sbjct: 47 QENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTA----KCALREIRITRELS-HE 101
Query: 322 NIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWC--CFKQIA 379
NII + ++ S G + +M D+ + + L+EK F QI
Sbjct: 102 NIINSTDVLMRES---GSGQDIYIVMDLMETDLLSVLK----SNQTLNEKHFQYFFYQIL 154
Query: 380 RGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDP-TSERIKIRG--- 435
+G++++HS GI HRD+K N+L+ + +LK+ DFG+S G P TS I G
Sbjct: 155 KGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLS 214
Query: 436 -YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFN--LVCPFALFA 492
Y + + PE+++ YD ++D W+ G ++ L+ P
Sbjct: 215 QYVSTLWYRAPEILL-------------SMGEYDT-QVDIWSAGCILAEMLLLRPIFTGT 260
Query: 493 EAHKDDSKYRHYIAFYEQFNKHSPHFRKPGV--YRSGPGAEHP-EFSKL---GSVEASRV 546
+++ Y+ ++ + + P + Y S G + P F+ + S+EA +
Sbjct: 261 DSYSQIQLLIEYLGTPDE--QVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNI 318
Query: 547 CLRLLDPDASTRYTIDDLFNDPWM 570
++L R++ + L +P++
Sbjct: 319 VSKMLQISPWKRFSAEQLLEEPFV 342
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 58.5 bits (140), Expect = 4e-08
Identities = 60/223 (26%), Positives = 97/223 (42%), Gaps = 33/223 (14%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHR-CITEFMIAKKVSNHVN 322
K +G G S+V + +K V ALK+ ++F E D + C+ E + K++ NH N
Sbjct: 49 KKIGRGQFSEVYKATCLLDRKTV-ALKKVQIF--EMMDAKARQDCVKEIGLLKQL-NHPN 104
Query: 323 IIKTF-YIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARG 381
IIK ++ ++ + + A + Q ++ L P W F Q+
Sbjct: 105 IIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLI-----PERTVWKYFVQLCSA 159
Query: 382 IRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPP 441
+ HMHS + HRDIK NV +T G +KL D G+ + +SE G+P
Sbjct: 160 VEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF-------SSETTAAHSLVGTPY 212
Query: 442 HVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
++ PE Y+ FK D W+LG L++ +
Sbjct: 213 YMSPE--------------RIHENGYN-FKSDIWSLGCLLYEM 240
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 58.5 bits (140), Expect = 4e-08
Identities = 32/111 (28%), Positives = 56/111 (49%), Gaps = 22/111 (19%)
Query: 375 FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIR 434
F+QI + + H + HRD+KLEN+L+ G +K+ DFG+S + ++
Sbjct: 156 FRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNL--------YHQGKFLQ 207
Query: 435 GYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
+CGSP + PE++ Y ++D+W+LG+L++ LV
Sbjct: 208 TFCGSPLYASPEIV--------------NGKPYTGPEVDSWSLGVLLYILV 244
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 58.5 bits (140), Expect = 4e-08
Identities = 99/401 (24%), Positives = 158/401 (38%), Gaps = 63/401 (15%)
Query: 125 SPKLESKSRTR----GASLLHKDREKDRDMNSN-MHVIKSSSAIPSLASHNTNPF--LNS 177
S K + KSR R +S D ++SN M+V +AIP S N NPF + S
Sbjct: 149 SSKSKKKSRKRRKHSSSSSSSSGEAMDLPVSSNGMNV----TAIPPPPSFNINPFQPMFS 204
Query: 178 ANGRIPL----ESLDVHSRPPTV-------SQAYHXXXXXXXXXXXXXLGFYQTEGDA-- 224
PL + + RPP S H QT+G A
Sbjct: 205 QPPPPPLPPNSQFMTPPPRPPPAPFSIPPPSVDIHFAATASFSLSSIPPPPPQTDGGASS 264
Query: 225 -KGENILPLPLKNPNDFLPESMQQPSVMLTDNFAFADSGRKT----------LGEGGSSQ 273
K ++ LP+P + + T+ + +DS KT +GEG Q
Sbjct: 265 SKRQDPLPMPPDSKRIATRPVITTRRGHATNRPSDSDSWYKTNLTHYTMLDQIGEGTYGQ 324
Query: 274 VMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTP 333
V + +QV ALKR +L ++ + F I E I +++ +H NI++ I+
Sbjct: 325 VYKAVNNLTGEQV-ALKRVRLENEK--EGFPITAIREIKILRQL-HHKNIVRLMDIVIDD 380
Query: 334 SVSNGPKRSWA---FLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMHSLGI 390
+ KR+ A + + D+ D+ FKQ+ G+ ++H+ G
Sbjct: 381 ISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGF 440
Query: 391 AHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMIL 450
HRDIK N+LV + G LK+ D G++ K+ T+ I + + PPE+++
Sbjct: 441 LHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLW-------YRPPELLL- 492
Query: 451 SXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALF 491
Y P +D W+ G ++ L LF
Sbjct: 493 ------------GDERYGP-AIDVWSTGCMLGELFTRKPLF 520
>CE17343 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 58.5 bits (140), Expect = 4e-08
Identities = 78/350 (22%), Positives = 129/350 (36%), Gaps = 63/350 (18%)
Query: 229 ILPLPLKNPNDFLPESMQQPSVMLTDNFAFADS--------GRKTLGEGGSSQVMTVHSI 280
I+ + +N D + E+ ++P + AFA + K LG G S+V +
Sbjct: 31 IVEMATENNTD-VSENQEEPDELSPKTKAFAPTLEKVWKLKFEKVLGSGSYSRVARA-TF 88
Query: 281 YRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPK 340
KK A K + + + + + K+ H NI + + ++
Sbjct: 89 GEKKLEVAAKIINITPTREKEDYIKKFLPREKEIVKLLKHDNICRLYEMISFQD------ 142
Query: 341 RSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENV 400
F+ + C A K D K+ F+Q+ + H+ S I HRD+K EN+
Sbjct: 143 -HIIFVNEYCAGGDLLRKMKDIVAMKEEDAKFT-FRQLIAALTHLQSYNIVHRDLKCENI 200
Query: 401 LVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXX 460
+ +G +KL DFG S +K E K +CGS +V PE+
Sbjct: 201 FMDKHGNVKLGDFGFSRI-LKPGE-------KSGTFCGSRAYVAPEIF------------ 240
Query: 461 XXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRK 520
Y +D W+ G++++ ++ F DD R I E+ H F K
Sbjct: 241 --RGREYSGNAVDVWSTGVILYIMLAGSMPF-----DDRDPRKMI---ERQLAHKIKFPK 290
Query: 521 PGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDASTRYTIDDLFNDPWM 570
S SV + + L +L P A R T + W+
Sbjct: 291 ---------------SCTSSVFSKALVLEILQPHAPNRPTYKAICESEWL 325
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 58.5 bits (140), Expect = 4e-08
Identities = 44/137 (32%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Query: 282 RKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKR 341
R ++ ALKR K+ K++ + F + E + K NH NI+ I+ SN K
Sbjct: 377 RTDEIVALKRLKMEKEK--EGFPITALREINMLLKAGNHPNIVNVKEILLG---SNMDKI 431
Query: 342 SWAFLMQQCVQDMFHYTTLSGWATK--PLDEKWCCFKQIARGIRHMHSLGIAHRDIKLEN 399
A M+ DM K + E+ +Q+ GI HMH L I HRD+K N
Sbjct: 432 YMA--MEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLWILHRDLKTSN 489
Query: 400 VLVTDYGALKLTDFGIS 416
+L++ G LK+ DFG++
Sbjct: 490 LLMSHKGILKIADFGLA 506
>At2g32850 [T] KOG1989 ARK protein kinase family
Length = 693
Score = 58.5 bits (140), Expect = 4e-08
Identities = 61/231 (26%), Positives = 93/231 (39%), Gaps = 25/231 (10%)
Query: 263 RKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
R + EGG S V + + YALK +E+ + + E + K + H N
Sbjct: 30 RNVIAEGGFSSVYLAQDVNHASKQYALKHMICNDEESLE----LVMKEISVLKSLKGHPN 85
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
++ T Y + K + M C + + G + F+ + +
Sbjct: 86 VV-TLYAHGILDMGRNKKEA-LLAMDFCGKSLVDVLENRGAGYFEEKQALTIFRDVCNAV 143
Query: 383 RHMH--SLGIAHRDIKLENVLVTDYGALKLTDFG-ISTYG--IKDPEDPTSERIKIRGYC 437
MH S IAHRD+K EN+L++ G KL DFG +ST + E+ E IR Y
Sbjct: 144 FAMHCQSPRIAHRDLKAENLLLSSDGQWKLCDFGSVSTNHKIFERAEEMGIEEDNIRKYT 203
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPF 488
+P + PE+ L K+D WALG L+F +C F
Sbjct: 204 -TPTYRAPEMWDLFRREMISE------------KVDIWALGCLLFR-ICYF 240
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 58.5 bits (140), Expect = 4e-08
Identities = 62/237 (26%), Positives = 104/237 (43%), Gaps = 45/237 (18%)
Query: 254 DNFAFADSGRKTLGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDET---PDHFYHRCITE 310
+NF F K LG+G +V+ + R+K L K+ K E D H +TE
Sbjct: 183 ENFEFL----KVLGKGTFGKVI----LCREKATAKLYAIKILKKEVIIQKDEVAHT-LTE 233
Query: 311 FMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLD 369
+ K +NH +I Y +T F+MQ ++F + + T+ D
Sbjct: 234 SRVLKS-TNHPFLISLKYSFQTND-------RLCFVMQYVNGGELFWHLSHERIFTE--D 283
Query: 370 EKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSE 429
+I + ++HS GI +RD+KLEN+L+ G +K+ DFG+ ED T
Sbjct: 284 RTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLC------KEDITYG 337
Query: 430 RIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
R + +CG+P ++ PEV+ + +D W G++M+ ++C
Sbjct: 338 R-TTKTFCGTPEYLAPEVLDDNDYGQA---------------VDWWGTGVVMYEMIC 378
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 58.5 bits (140), Expect = 4e-08
Identities = 80/329 (24%), Positives = 130/329 (39%), Gaps = 58/329 (17%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+GEG QV + V ALK+ +L + + F + E I +++ NH NI+
Sbjct: 810 IGEGTYGQVYKARDHHTNDMV-ALKKVRL--EHEKEGFPITAVREIKILRQL-NHRNIVN 865
Query: 326 TFYIM--KTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIR 383
I+ K +V + +L+ + + SG + KQ+ G+
Sbjct: 866 LHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLN 925
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS-TYGIKDPEDPTSERIKIRGYCGSPPH 442
+ H HRDIK N+L+ + G +KL DFG++ Y D E P + ++ Y
Sbjct: 926 YCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWY------ 979
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKDDSKYR 502
PPE+++ Y P +D W+ G ++ L LF +A+ +
Sbjct: 980 RPPELLL-------------GEERYGP-SIDVWSCGCILGELFVKRPLF-QANAE----- 1019
Query: 503 HYIAFYEQFNK--HSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLR----------- 549
+A E +K SP P V+ + + P F L + R LR
Sbjct: 1020 --MAQLETISKICGSP---VPAVWPN--VIKLPLFHTLKQKKTHRRRLREDFEFMPAPAL 1072
Query: 550 -----LLDPDASTRYTIDDLFNDPWMAKI 573
+LD D R T +D PW+ KI
Sbjct: 1073 DLLDKMLDLDPDKRITAEDALRSPWLRKI 1101
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 58.2 bits (139), Expect = 5e-08
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 47/193 (24%)
Query: 378 IARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYC 437
IA ++++H+ I HRD+K+EN++++ G +K+ DFG+S R ++ +C
Sbjct: 232 IASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNI--------FDYRKQLHTFC 283
Query: 438 GSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAHKD 497
GS PE++ Y ++D W+ GI+++ LVC F + +
Sbjct: 284 GSLYFAAPELL--------------KAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSS 329
Query: 498 DSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCLRLLDPDAST 557
+E+ K ++P S+E + R++ D
Sbjct: 330 --------ILHEKIKKGK--------------VDYPSHL---SIEVISLLTRMIVVDPLR 364
Query: 558 RYTIDDLFNDPWM 570
R T+ ++ PWM
Sbjct: 365 RATLKNVVEHPWM 377
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 58.2 bits (139), Expect = 5e-08
Identities = 46/177 (25%), Positives = 79/177 (43%), Gaps = 35/177 (19%)
Query: 312 MIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ--DMFHYTTLSGWATKPLD 369
++ K+ +H N++ F + + +S +L+ + V ++F Y G P
Sbjct: 165 IVIMKLISHTNVMALFEVWEN--------KSELYLVLEYVDGGELFDYLVSKG--KLPER 214
Query: 370 EKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYG-ALKLTDFGISTYGIKDPEDPTS 428
E FKQI G+ + HS I HRD+K EN+L+ +K+ DFG++ + + TS
Sbjct: 215 EAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTS 274
Query: 429 ERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
CGSP + PE+++ Y D W+ GI++F L+
Sbjct: 275 --------CGSPHYASPEIVM--------------GRPYHGGPSDVWSCGIVLFALL 309
>SPBC337.04 [R] KOG0586 Serine/threonine protein kinase
Length = 413
Score = 58.2 bits (139), Expect = 5e-08
Identities = 43/166 (25%), Positives = 76/166 (44%), Gaps = 30/166 (18%)
Query: 353 DMFHYTTLSGWATKPLDEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTD-YGALKLT 411
D++HYT + L+ F ++ + ++HS + HRD+KLEN+L+T Y +K
Sbjct: 191 DLYHYTK-KHHSDFSLEFVGRIFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTI 249
Query: 412 D---------FGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXX 462
D IS + + D S+ ++ CGS + PPEV +
Sbjct: 250 DNWKNYPNALIQISDFELSIFVD--SKNHLVQSSCGSQEYAPPEVYM------------- 294
Query: 463 XXXXYDPFKMDTWALGILMFNLV---CPFALFAEAHKDDSKYRHYI 505
+D F+ D W+LGI++F L+ PF + ++ + + Y+
Sbjct: 295 -GIAHDGFRADAWSLGIVLFALLEGRLPFDSYPTLDPENVRIKRYV 339
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 51/206 (24%)
Query: 374 CFKQIARGIRHMHSLGIAHRDIKLENVLVTDY---GALKLTDFGISTYGIKDPEDPTSER 430
C +QI I + HS GI HRD+K EN+L+ A+KL DFG++ + D E
Sbjct: 114 CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLA-IEVNDSE------ 166
Query: 431 IKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFK--MDTWALGILMFNLVCPF 488
G+ G+P ++ PEV+ DP+ +D WA G++++ L+ +
Sbjct: 167 -AWHGFAGTPGYLSPEVL-----------------KKDPYSKPVDIWACGVILYILLVGY 208
Query: 489 ALFAEAHKDDSKYRHYIAFYEQFNKHSPHFRKPGVYRSGPGAEHPEFSKLGSVEASRVCL 548
F D+ ++R Y K G Y PE+ + + EA +
Sbjct: 209 PPF----WDEDQHRLYAQI------------KAGAY----DYPSPEWDTV-TPEAKSLID 247
Query: 549 RLLDPDASTRYTIDDLFNDPWMAKIE 574
+L + R T D PW+ E
Sbjct: 248 SMLTVNPKKRITADQALKVPWICNRE 273
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 58.2 bits (139), Expect = 5e-08
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 22/109 (20%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+I + H+H GI +RD+K EN+L+ YG +KLTDFG+ I+ + K +
Sbjct: 193 EIVVSLEHLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQ-------KTHTF 245
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
CG+ ++ PE+++ +D W+LG LMF+++
Sbjct: 246 CGTIEYMAPEILMRCGHGKA---------------VDWWSLGALMFDML 279
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 58.2 bits (139), Expect = 5e-08
Identities = 82/340 (24%), Positives = 136/340 (39%), Gaps = 73/340 (21%)
Query: 264 KTLGEGGSSQVMTVHSIYRKKQ---VYALK----RFKLFKDETPDHFYHRCITEFMIAKK 316
K G G S+V+ +KK+ VYALK +F +++T R + + +
Sbjct: 45 KIYGVGSYSKVVRA----KKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQL---- 96
Query: 317 VSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQ-DMFHYTTLSGWATKPLDEKWCCF 375
H IIK ++ + S S ++ C ++F T G ++ DE
Sbjct: 97 --EHPGIIKLYFTFQDTS-------SLYMALESCEGGELFDQITRKGRLSE--DEARFYT 145
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPE----DPTSERI 431
++ + ++HS+G+ HRDIK EN+L+T G +K+ DFG S ++D + +
Sbjct: 146 AEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFG-SVKPMQDSQITVLPNAASDD 204
Query: 432 KIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALF 491
K + G+ +VPPEV+ S F D WALG ++ ++ + F
Sbjct: 205 KACTFVGTAAYVPPEVLNSSPAT---------------FGNDLWALGCTLYQMLSGTSPF 249
Query: 492 AEAHKDDSKYRHYIAFYEQFNKHSPHF-----------------RKPGVYRSGPGA--EH 532
KD S++ + + K HF R+PG G A H
Sbjct: 250 ----KDASEWLIFQRIIARDIKFPNHFSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRH 305
Query: 533 PEFSKLGSVEASRVCLRLLDPDASTRYTI---DDLFNDPW 569
P F+ + L PD +++ DD PW
Sbjct: 306 PFFNGVDWKNLRSQTPPKLAPDPASQTASPERDDTHGSPW 345
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 58.2 bits (139), Expect = 5e-08
Identities = 33/111 (29%), Positives = 60/111 (53%), Gaps = 26/111 (23%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGY 436
+IA G+ +H+ GI +RD+KL+NVL+ G +K+ DFG+ I D T+ + +
Sbjct: 457 EIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVG--DKTT-----KTF 509
Query: 437 CGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPF--KMDTWALGILMFNLV 485
CG+P ++ PE+++ Y P+ +D WA G+L++ ++
Sbjct: 510 CGTPDYIAPEIIL-----------------YQPYGKSVDWWAYGVLLYEML 543
>YHR082c [T] KOG0583 Serine/threonine protein kinase
Length = 1029
Score = 57.8 bits (138), Expect = 7e-08
Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 17/131 (12%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYG-ALKLTDFGISTYGIKDPEDPTSERIKIRG 435
QI I ++H+ GI HRDIK EN+L++ +KLTD+G++ T+++ +
Sbjct: 190 QIMDAIEYVHNKGIYHRDIKPENILISGIDWTIKLTDWGLA----------TTDKTSMDR 239
Query: 436 YCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
GS ++ PE+ YD K+D WA+GI+ N+V F+ A+
Sbjct: 240 NVGSERYMSPELF------DSNLDIKERKEPYDCAKVDLWAMGIVFLNIVFHKNPFSIAN 293
Query: 496 KDDSKYRHYIA 506
+ D + ++ A
Sbjct: 294 QSDKSFCYFAA 304
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 57.8 bits (138), Expect = 7e-08
Identities = 49/224 (21%), Positives = 98/224 (42%), Gaps = 36/224 (16%)
Query: 264 KTLGEGGSSQV-MTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVN 322
KTLGEG +V + H+ +K + K+ R I+ + + H +
Sbjct: 59 KTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR----HPH 114
Query: 323 IIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGI 382
IIK + ++K+ K +++ ++F Y ++ ++ F+QI +
Sbjct: 115 IIKLYDVIKS-------KDEIIMVIEYAGNELFDYIVQRDKMSEQEARRF--FQQIISAV 165
Query: 383 RHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPH 442
+ H I HRD+K EN+L+ ++ +K+ DFG+S ++ ++ CGSP +
Sbjct: 166 EYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNI--------MTDGNFLKTSCGSPNY 217
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVC 486
PEV+ Y ++D W+ G++++ ++C
Sbjct: 218 AAPEVI--------------SGKLYAGPEVDVWSCGVILYVMLC 247
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 57.8 bits (138), Expect = 7e-08
Identities = 57/211 (27%), Positives = 92/211 (43%), Gaps = 29/211 (13%)
Query: 252 LTDNFAFADSGRKTLGEGGSSQVMTVHSIYRKK--QVYALKRFKLFKDETPDHFYHRCIT 309
LTD G T GE SQ R+K +VYALKR + ++ + F I
Sbjct: 33 LTDYHLMEKLGEGTFGEVYKSQ--------RRKDGKVYALKRILMHTEK--EGFPITAIR 82
Query: 310 EFMIAKKVSNHVNIIKTFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPL- 368
E I K + H NII + + +R +++ + LSG P
Sbjct: 83 EIKILKSIK-HENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDH-----DLSGLLENPSV 136
Query: 369 ----DEKWCCFKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGIS------TY 418
+ C KQ+ G +++H I HRD+K N+L+ ++G LK+ DFG++ +Y
Sbjct: 137 KFTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESY 196
Query: 419 GIKDPEDPTSERIKIRGYCGSPPHVPPEVMI 449
K+P P R + G + + PE+++
Sbjct: 197 ANKNPGLPPPNRREYTGCVVTRWYRSPELLL 227
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 57.8 bits (138), Expect = 7e-08
Identities = 56/233 (24%), Positives = 100/233 (42%), Gaps = 34/233 (14%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+GEG V + + K +V A+K+ F+ +T + R + E I + H NII
Sbjct: 31 IGEGAYGMVCSAYDNVNKVRV-AIKKISPFEHQT---YCQRTLREIKILLRF-RHENIIG 85
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIR 383
I++ P++ VQD+ T+ L C+ QI RG++
Sbjct: 86 INDIIRAPTIEQMKD-------VYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLK 138
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPE-DPTSERIKIRGYCGSPPH 442
++HS + HRD+K N+L+ LK+ DFG++ + DP+ D T + Y + +
Sbjct: 139 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR--VADPDHDHTG---FLTEYVATRWY 193
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
PE+M+ S +D W++G ++ ++ +F H
Sbjct: 194 RAPEIMLNSKGYTK--------------SIDIWSVGCILAEMLSNRPIFPGKH 232
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 57.8 bits (138), Expect = 7e-08
Identities = 56/233 (24%), Positives = 100/233 (42%), Gaps = 34/233 (14%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+GEG V + + K +V A+K+ F+ +T + R + E I + H NII
Sbjct: 31 IGEGAYGMVCSAYDNVNKVRV-AIKKISPFEHQT---YCQRTLREIKILLRF-RHENIIG 85
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCF--KQIARGIR 383
I++ P++ VQD+ T+ L C+ QI RG++
Sbjct: 86 INDIIRAPTIEQMKD-------VYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLK 138
Query: 384 HMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPE-DPTSERIKIRGYCGSPPH 442
++HS + HRD+K N+L+ LK+ DFG++ + DP+ D T + Y + +
Sbjct: 139 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR--VADPDHDHTG---FLTEYVATRWY 193
Query: 443 VPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAEAH 495
PE+M+ S +D W++G ++ ++ +F H
Sbjct: 194 RAPEIMLNSKGYTK--------------SIDIWSVGCILAEMLSNRPIFPGKH 232
>CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 521
Score = 57.8 bits (138), Expect = 7e-08
Identities = 38/119 (31%), Positives = 57/119 (46%), Gaps = 26/119 (21%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYG---ALKLTDFGISTYGIKDPEDPTSERIK 432
+QI + ++H + IAHRDIKLEN+L + G KL D+G + K PE +
Sbjct: 248 RQIGNAVMYLHDMNIAHRDIKLENILCSGTGDNCVYKLGDYGFA----KRPE----RNVL 299
Query: 433 IRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALF 491
+ C +P + PPEV+ YD D W+LG+ M+ L+C + F
Sbjct: 300 MESPCCTPFYAPPEVL--------------GRERYDK-SCDMWSLGVAMYILLCGYPPF 343
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 57.8 bits (138), Expect = 7e-08
Identities = 54/221 (24%), Positives = 94/221 (42%), Gaps = 32/221 (14%)
Query: 266 LGEGGSSQVMTVHSIYRKKQVYALKRFKLFKDETPDHFYHRCITEFMIAKKVSNHVNIIK 325
+G+G S V + K + ALK+ + D E ++ +++ NH N+IK
Sbjct: 120 IGQGTYSNVYKAKDLLSGK-IVALKKVRF--DNLEAESVKFMAREILVLRRL-NHPNVIK 175
Query: 326 TFYIMKTPSVSNGPKRSWAFLMQQCVQDMFHYTTLSGWATKPLDEKWCCFKQIARGIRHM 385
+ V++ S + + D+ G L + C KQ+ G+ H
Sbjct: 176 LQGL-----VTSRVSCSLYLVFEYMEHDLSGLAATQGLKFD-LPQVKCFMKQLLSGLEHC 229
Query: 386 HSLGIAHRDIKLENVLVTDYGALKLTDFGIST-YGIKDPEDPTSERIKIRGYCGSPPHVP 444
HS G+ HRDIK N+L+ + G LK+ DFG++T Y K + TS + + + P
Sbjct: 230 HSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSRVVTLW-------YRP 282
Query: 445 PEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLV 485
PE+++ + +D W+ G +M L+
Sbjct: 283 PELLLGATSYGTG--------------VDLWSAGCIMAELL 309
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 57.8 bits (138), Expect = 7e-08
Identities = 35/143 (24%), Positives = 62/143 (42%), Gaps = 39/143 (27%)
Query: 377 QIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTS-------- 428
++ + ++HS G+ HRD+K +N+L+ G +KLTDFG+S G+ + D +
Sbjct: 996 EVVLALEYLHSEGVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTS 1055
Query: 429 ----------------ERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKM 472
ER K R G+P ++ PE+++ +
Sbjct: 1056 LLDEEESRLAASEEQLERRKKRSAVGTPDYLAPEILLGTGHGATA--------------- 1100
Query: 473 DTWALGILMFNLVCPFALFAEAH 495
D W++GI++F L+ F H
Sbjct: 1101 DWWSVGIILFELIVGIPPFNAEH 1123
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 57.4 bits (137), Expect = 9e-08
Identities = 33/107 (30%), Positives = 62/107 (57%), Gaps = 18/107 (16%)
Query: 351 VQDMFHYTTLSGW------ATKPLDEKWCCF--KQIARGIRHMHSLGIAHRDIKLENVLV 402
++D++ T L G T+PL++++ + QI RG++++HS G+ HRD+K N+L+
Sbjct: 93 LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILI 152
Query: 403 TDYGALKLTDFGISTYGIKDPEDPTSERIKIRGYCGSPPHVPPEVMI 449
+ LK+ DFG++ I+DP+ + GY + + PE+M+
Sbjct: 153 NENCDLKICDFGLAR--IQDPQ--------MTGYVSTRYYRAPEIML 189
>YGR052w [T] KOG0583 Serine/threonine protein kinase
Length = 369
Score = 57.4 bits (137), Expect = 9e-08
Identities = 43/140 (30%), Positives = 65/140 (45%), Gaps = 15/140 (10%)
Query: 376 KQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPEDPTSERIKIRG 435
KQ+ I HSLGIAHRDIK EN+L+T G +KL D+G + + P S +I
Sbjct: 115 KQLCSAISFAHSLGIAHRDIKPENILLTINGDIKLADWGHAI------QSPKSNDFQI-- 166
Query: 436 YCGSPPHVPPEVMI--LSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNLVCPFALFAE 493
G+ + PE +S Y+ ++ D W+LG +F L+ LF
Sbjct: 167 --GTDNYRAPETFSGRVSNSCFKKNFDRSSAPLYNTYQADYWSLGATIFYLMFGDCLF-- 222
Query: 494 AHKDDSKYRHYIAFYEQFNK 513
SK ++ +++F K
Sbjct: 223 -RVSKSKKVQHLKNFDEFEK 241
>HsM5454174 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 57.4 bits (137), Expect = 9e-08
Identities = 40/120 (33%), Positives = 60/120 (49%), Gaps = 24/120 (20%)
Query: 367 PLDEKWCC--FKQIARGIRHMHSLGIAHRDIKLENVLVTDYGALKLTDFGISTYGIKDPE 424
PL+E + ++I +G+ ++HS HRDIK NVL+++ G +KL DFG++
Sbjct: 111 PLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVA-------G 163
Query: 425 DPTSERIKIRGYCGSPPHVPPEVMILSXXXXXXXXXXXXXXXYDPFKMDTWALGILMFNL 484
T +IK + G+P + PEV+ S YD FK D W+LGI L
Sbjct: 164 QLTDTQIKRNTFVGTPFWMAPEVIKQS--------------AYD-FKADIWSLGITAIEL 208
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.132 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,577,557
Number of Sequences: 60738
Number of extensions: 1637407
Number of successful extensions: 6777
Number of sequences better than 1.0e-05: 463
Number of HSP's better than 0.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 412
Number of HSP's that attempted gapping in prelim test: 6048
Number of HSP's gapped (non-prelim): 555
length of query: 817
length of database: 30,389,216
effective HSP length: 115
effective length of query: 702
effective length of database: 23,404,346
effective search space: 16429850892
effective search space used: 16429850892
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)