ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1632 check: MH U KOG0935 Intracellular trafficking, secretion, and vesicular transport Clathrin adaptor complex, small subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1632 583095 583538 148
(148 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR058c [U] KOG0935 Clathrin adaptor complex small subunit 202 1e-52
At1g47830 [U] KOG0935 Clathrin adaptor complex small subunit 138 3e-33
SPBC685.04c [U] KOG0935 Clathrin adaptor complex small subunit 135 3e-32
Hs4757996 [U] KOG0935 Clathrin adaptor complex small subunit 132 1e-31
7300728 [U] KOG0935 Clathrin adaptor complex small subunit 132 2e-31
CE07018 [U] KOG0935 Clathrin adaptor complex small subunit 129 1e-30
Hs18551999 [U] KOG0934 Clathrin adaptor complex small subunit 127 5e-30
SPAP27G11.06c [U] KOG0934 Clathrin adaptor complex small subunit 126 1e-29
At4g35410 [U] KOG0934 Clathrin adaptor complex small subunit 120 5e-28
Hs22027655 [U] KOG0934 Clathrin adaptor complex small subunit 119 1e-27
At2g17380 [U] KOG0934 Clathrin adaptor complex small subunit 119 1e-27
Hs4557471 [U] KOG0934 Clathrin adaptor complex small subunit 118 2e-27
CE09797 [U] KOG0934 Clathrin adaptor complex small subunit 116 9e-27
Hs22066144 [U] KOG0934 Clathrin adaptor complex small subunit 114 4e-26
7301077 [U] KOG0934 Clathrin adaptor complex small subunit 111 4e-25
Hs16950628 [U] KOG0934 Clathrin adaptor complex small subunit 107 6e-24
YLR170c [U] KOG0934 Clathrin adaptor complex small subunit 106 1e-23
At2g19790 [U] KOG0934 Clathrin adaptor complex small subunit 105 2e-23
At3g50860 [U] KOG0936 Clathrin adaptor complex small subunit 102 2e-22
HsM5901934 [U] KOG0934 Clathrin adaptor complex small subunit 97 1e-20
Hs4502861 [U] KOG0936 Clathrin adaptor complex small subunit 91 7e-19
Hs5031581 [U] KOG0936 Clathrin adaptor complex small subunit 90 9e-19
Hs11038643 [U] KOG0935 Clathrin adaptor complex small subunit 82 3e-16
SPAC30D11.05 [U] KOG0936 Clathrin adaptor complex small subunit 77 1e-14
7291698 [U] KOG0936 Clathrin adaptor complex small subunit 77 1e-14
Hs21361394 [U] KOG0934 Clathrin adaptor complex small subunit 74 9e-14
YJL024c [U] KOG0936 Clathrin adaptor complex small subunit 73 2e-13
Hs20539280 [U] KOG0934 Clathrin adaptor complex small subunit 60 1e-09
>YJR058c [U] KOG0935 Clathrin adaptor complex small subunit
Length = 147
Score = 202 bits (514), Expect = 1e-52
Identities = 98/148 (66%), Positives = 119/148 (80%), Gaps = 1/148 (0%)
Query: 1 MPVQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKH 60
M VQFILC NKQG+VRL+RWF+ + +S Q+ I Q++++IS RDH+ QSNF+EFS
Sbjct: 1 MAVQFILCFNKQGVVRLVRWFD-VHSSDPQRSQDAIAQIYRLISSRDHKHQSNFVEFSDS 59
Query: 61 TKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVM 120
TKL+Y+ YAGLYFVMGVD D+E IYL IHLFVEVLD+FFGNVCELDI+FNFYK Y++M
Sbjct: 60 TKLIYRRYAGLYFVMGVDLLDDEPIYLCHIHLFVEVLDAFFGNVCELDIVFNFYKVYMIM 119
Query: 121 DEMFIAGEIQTTSKKELLERIGQLDRLN 148
DEMFI GEIQ SK LLER+ LDRL+
Sbjct: 120 DEMFIGGEIQEISKDMLLERLSILDRLD 147
>At1g47830 [U] KOG0935 Clathrin adaptor complex small subunit
Length = 142
Score = 138 bits (347), Expect = 3e-33
Identities = 70/146 (47%), Positives = 106/146 (71%), Gaps = 7/146 (4%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQ-EYIRQVFKVISQRDHRRQSNFIEFSKHT 61
++FIL N+QG RL +++ L+ S+ H+ EY +V +++ RD + +NF+EF H
Sbjct: 2 IRFILLQNRQGKTRLAKYYVPLEESE--KHKVEY--EVHRLVVNRD-AKFTNFVEFRTH- 55
Query: 62 KLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMD 121
K++Y+ YAGL+F + VD D EL YL IHLFVE+LD FF NVCELD++FNF+K YL++D
Sbjct: 56 KVIYRRYAGLFFSVCVDITDNELAYLESIHLFVEILDHFFSNVCELDLVFNFHKVYLILD 115
Query: 122 EMFIAGEIQTTSKKELLERIGQLDRL 147
E +AGE+Q TSK+ ++ER+ +L++L
Sbjct: 116 EFILAGELQETSKRAIIERMSELEKL 141
>SPBC685.04c [U] KOG0935 Clathrin adaptor complex small subunit
Length = 143
Score = 135 bits (339), Expect = 3e-32
Identities = 69/145 (47%), Positives = 99/145 (67%), Gaps = 4/145 (2%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
+QFIL N+ G RL +++ D + + I Q+ ISQR+ + Q+NF+E+ +++K
Sbjct: 2 IQFILIQNRHGKNRLSKYYVPFDDDEKVRLKARIHQL---ISQRNQKFQANFLEW-ENSK 57
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
LVY+ YAGLYF VD D +L L IH FVE+LDSFFGNVCELD++FNFYK ++DE
Sbjct: 58 LVYRRYAGLYFCFCVDSTDNDLAILEMIHFFVEILDSFFGNVCELDLIFNFYKVSAILDE 117
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
+ + GEI ++KK +LERI L++L
Sbjct: 118 IILGGEIGESNKKSVLERIEALEKL 142
>Hs4757996 [U] KOG0935 Clathrin adaptor complex small subunit
Length = 142
Score = 132 bits (333), Expect = 1e-31
Identities = 67/145 (46%), Positives = 101/145 (69%), Gaps = 5/145 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++FIL N+ G RL +W+ + D + Q+ I +V V++ RD + +NF+EF ++ K
Sbjct: 2 IRFILIQNRAGKTRLAKWYMQFDDDE---KQKLIEEVHAVVTVRD-AKHTNFVEF-RNFK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
++Y+ YAGLYF + VD D +L YL IH FVEVL+ +F NVCELD++FNFYK Y V+DE
Sbjct: 57 IIYRRYAGLYFCICVDVNDNKLAYLEGIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
MF+AGEI+ TS+ ++L+++ L L
Sbjct: 117 MFLAGEIRETSQTKVLKQLLMLQSL 141
>7300728 [U] KOG0935 Clathrin adaptor complex small subunit
Length = 142
Score = 132 bits (332), Expect = 2e-31
Identities = 68/145 (46%), Positives = 100/145 (68%), Gaps = 5/145 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++FIL N+ G RL +W+ D + Q+ I +V V++ RD + +NF+EF ++ K
Sbjct: 2 IRFILIQNRAGKTRLAKWYMNFDDDE---KQKLIEEVHAVVTVRD-AKHTNFVEF-RNFK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
+VY+ YAGLYF + VD D L YL IH FVEVL+ +F NVCELD++FNFYK Y V+DE
Sbjct: 57 IVYRRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
MF+AGEI+ TS+ ++L+++ L+ L
Sbjct: 117 MFLAGEIRETSQTKVLKQLLTLNSL 141
>CE07018 [U] KOG0935 Clathrin adaptor complex small subunit
Length = 142
Score = 129 bits (324), Expect = 1e-30
Identities = 67/145 (46%), Positives = 98/145 (67%), Gaps = 5/145 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++FIL N+ G RL +W+ D + Q+ I +V ++ RD + +NF+EF ++ K
Sbjct: 2 IRFILIQNRAGKTRLAKWYMHFDDDE---KQKLIEEVHACVTVRD-AKHTNFVEF-RNFK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
+VY+ YAGLYF + VD D L YL IH FVEVL+ +F NVCELD++FNFYK Y V+DE
Sbjct: 57 IVYRRYAGLYFCICVDITDNNLYYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
MF+AGEI+ TS+ ++L+++ L L
Sbjct: 117 MFLAGEIRETSQTKVLKQLLMLTSL 141
>Hs18551999 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 164
Score = 127 bits (319), Expect = 5e-30
Identities = 65/145 (44%), Positives = 94/145 (64%), Gaps = 5/145 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
+ FIL ++QG +RL +W+ L + ++ R++ ++I R HR S+F+++ K K
Sbjct: 2 IHFILLFSRQGKLRLQKWYITLPDKE---RKKITREIVQIILSRGHRT-SSFVDW-KELK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
LVYK YA LYF ++ QD EL+ L +H +VE+LD +FGNVCELDI+FNF K Y ++DE
Sbjct: 57 LVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
I GEIQ TSKK ++ I D L
Sbjct: 117 FIIGGEIQETSKKIAVKAIEDSDML 141
>SPAP27G11.06c [U] KOG0934 Clathrin adaptor complex small subunit
Length = 162
Score = 126 bits (316), Expect = 1e-29
Identities = 64/141 (45%), Positives = 93/141 (65%), Gaps = 5/141 (3%)
Query: 1 MPVQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKH 60
M ++F L +++QG VRL +WF L + A + IR V ++ R + NF+E+ K
Sbjct: 1 MSIKFFLLVSRQGKVRLAKWFNTLSIKERA---KIIRDVSSLVITRKPK-MCNFVEY-KG 55
Query: 61 TKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVM 120
K+VY+ YA L+FV G+++ D ELI L IH FVE LD +FGNVCELD++FNF K Y VM
Sbjct: 56 EKIVYRRYASLFFVCGIEQDDNELIILEVIHKFVECLDKYFGNVCELDLIFNFEKAYYVM 115
Query: 121 DEMFIAGEIQTTSKKELLERI 141
+E+ +AGE+Q +SK +L +
Sbjct: 116 EELLLAGELQESSKTNVLSAV 136
>At4g35410 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 162
Score = 120 bits (302), Expect = 5e-28
Identities = 65/147 (44%), Positives = 98/147 (66%), Gaps = 9/147 (6%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQ--EYIRQVFKVISQRDHRRQSNFIEFSKH 60
+ F+L +++QG VRL +W+ S YA + + IR++ VI R + NF+E+ +
Sbjct: 2 IHFVLLVSRQGKVRLTKWY-----SPYAQKERSKVIRELSGVILNRGPKL-CNFVEWRGY 55
Query: 61 TKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVM 120
K+VYK YA LYF M +D++D EL L IH +VE+LD +FG+VCELD++FNF+K Y ++
Sbjct: 56 -KVVYKRYASLYFCMCIDQEDNELEVLEIIHHYVEILDRYFGSVCELDLIFNFHKAYYIL 114
Query: 121 DEMFIAGEIQTTSKKELLERIGQLDRL 147
DE+ IAGE+Q +SKK + I D+L
Sbjct: 115 DELLIAGELQESSKKTVARIISAQDQL 141
>Hs22027655 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 157
Score = 119 bits (299), Expect = 1e-27
Identities = 62/145 (42%), Positives = 94/145 (64%), Gaps = 5/145 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
+QF+L ++QG +RL +W+ L + ++ R++ + + R + S F+E+ + K
Sbjct: 1 MQFMLLFSRQGKLRLQKWYVPLSDKE---KKKITRELVQTVLARKPKMCS-FLEW-RDLK 55
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
+VYK YA LYF ++ QD ELI L IH +VE+LD +FG+VCELDI+FNF K Y ++DE
Sbjct: 56 IVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDE 115
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
+ GE+Q TSKK +L+ I Q D L
Sbjct: 116 FLLGGEVQETSKKNVLKAIEQADLL 140
>At2g17380 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 161
Score = 119 bits (299), Expect = 1e-27
Identities = 63/145 (43%), Positives = 94/145 (64%), Gaps = 5/145 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
+ F+L +++QG VRL +W+ + + IR++ VI R + NFIE+ + K
Sbjct: 2 IHFVLLVSRQGKVRLTKWYSPYTQKE---RSKVIRELSGVILNRGPKL-CNFIEWRGY-K 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
+VYK YA LYF M +D+ D EL L IH +VE+LD +FG+VCELD++FNF+K Y ++DE
Sbjct: 57 VVYKRYASLYFCMCIDEADNELEVLEIIHHYVEILDRYFGSVCELDLIFNFHKAYYILDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
+ IAGE+Q +SKK + I D+L
Sbjct: 117 LLIAGELQESSKKTVARIISAQDQL 141
>Hs4557471 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 158
Score = 118 bits (296), Expect = 2e-27
Identities = 63/145 (43%), Positives = 97/145 (66%), Gaps = 5/145 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++F+L ++QG +RL +W+ L TS ++ +R++ +V+ R + S F+E+ + K
Sbjct: 2 MRFMLLFSRQGKLRLQKWY--LATSD-KERKKMVRELMQVVLARKPKMCS-FLEW-RDLK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
+VYK YA LYF ++ QD ELI L IH +VE+LD +FG+VCELDI+FNF K Y ++DE
Sbjct: 57 VVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
+ G++Q TSKK +L+ I Q D L
Sbjct: 117 FLMGGDVQDTSKKSVLKAIEQADLL 141
>CE09797 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 157
Score = 116 bits (291), Expect = 9e-27
Identities = 61/143 (42%), Positives = 92/143 (63%), Gaps = 5/143 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
+Q++L ++QG +RL +W+ Q ++ R++ I R + + F+E+ K K
Sbjct: 2 MQYMLLFSRQGKLRLQKWYTAYPDKQ---KKKICRELITQILARKPKMCA-FLEY-KDLK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
+VYK YA LYF +++ D ELI L IH +VE+LD +FG+VCELDI+FNF K Y ++DE
Sbjct: 57 VVYKRYASLYFCCAIEQNDNELITLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLD 145
+AGEIQ TSKK++L+ I D
Sbjct: 117 FLLAGEIQETSKKQVLKAIAAQD 139
>Hs22066144 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 269
Score = 114 bits (286), Expect = 4e-26
Identities = 59/141 (41%), Positives = 91/141 (63%), Gaps = 5/141 (3%)
Query: 7 LCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTKLVYK 66
+ +++QG +RL +W+ L + ++ R++ + + R + S F+E+ + K+VYK
Sbjct: 114 ISISRQGKLRLQKWYVPLSDKE---KKKITRELVQTVLARKPKMCS-FLEW-RDLKIVYK 168
Query: 67 GYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDEMFIA 126
YA LYF ++ QD ELI L IH +VE+LD +FG+VCELDI+FNF K Y ++DE +
Sbjct: 169 RYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG 228
Query: 127 GEIQTTSKKELLERIGQLDRL 147
GE+Q TSKK +L+ I Q D L
Sbjct: 229 GEVQETSKKNVLKAIEQADLL 249
>7301077 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 153
Score = 111 bits (277), Expect = 4e-25
Identities = 60/142 (42%), Positives = 88/142 (61%), Gaps = 5/142 (3%)
Query: 6 ILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTKLVY 65
+L ++QG +RL +W+ ++ R++ I R + S F+E+ K K+VY
Sbjct: 1 MLLFSRQGKLRLQKWYMAYPDK---VKKKITRELVTTILARKPKMCS-FLEW-KDCKIVY 55
Query: 66 KGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDEMFI 125
K YA LYF +++ D EL+ L IH +VE+LD +FG+VCELDI+FNF K Y ++DE+ I
Sbjct: 56 KRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLI 115
Query: 126 AGEIQTTSKKELLERIGQLDRL 147
GEIQ TSKK +L+ I D L
Sbjct: 116 GGEIQETSKKNVLKAIASQDLL 137
>Hs16950628 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 133
Score = 107 bits (267), Expect = 6e-24
Identities = 56/131 (42%), Positives = 88/131 (66%), Gaps = 5/131 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++F+L ++QG +RL +W+ L TS ++ +R++ +V+ R + S F+E+ + K
Sbjct: 2 MRFMLLFSRQGKLRLQKWY--LATSD-KERKKMVRELMQVVLARKPKMCS-FLEW-RDLK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
+VYK YA LYF ++ QD ELI L IH +VE+LD +FG+VCELDI+FNF K Y ++DE
Sbjct: 57 VVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDE 116
Query: 123 MFIAGEIQTTS 133
+ G++Q TS
Sbjct: 117 FLMGGDVQDTS 127
>YLR170c [U] KOG0934 Clathrin adaptor complex small subunit
Length = 156
Score = 106 bits (264), Expect = 1e-23
Identities = 56/147 (38%), Positives = 94/147 (63%), Gaps = 7/147 (4%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++++L +++QG +RL +W+ + + A + ++ + I R + N IE++ H K
Sbjct: 4 LKYLLLVSRQGKIRLKKWYTAMSAGEKA---KIVKDLTPTILARKPK-MCNIIEYNDH-K 58
Query: 63 LVYKGYAGLYFVMGVDKQ-DEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMD 121
+VYK YA LYF++G+ D EL+ L IH FVE +D++FGNVCELDI+FNF K Y +++
Sbjct: 59 VVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVCELDIIFNFSKVYDILN 118
Query: 122 EMFIA-GEIQTTSKKELLERIGQLDRL 147
EM + G I +S+KE+L + +D +
Sbjct: 119 EMIMCDGSIAESSRKEVLHHVTVMDTM 145
>At2g19790 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 143
Score = 105 bits (262), Expect = 2e-23
Identities = 60/147 (40%), Positives = 92/147 (61%), Gaps = 7/147 (4%)
Query: 1 MPVQFILCLNKQGIVRLLRWFEKLDTSQY-ATHQEYIRQVFKVISQRDHRRQSNFIEFSK 59
M ++FIL +NKQG RL +++E L + A E +R K +++ D +Q +F+E
Sbjct: 1 MGIRFILMVNKQGQTRLAQYYEWLTLEERRALEGEIVR---KCLARND--QQCSFVEHRN 55
Query: 60 HTKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLV 119
+ K+VY+ YA L+F++GVD + EL L IHL VE +D FGNVCELDI+F+ K + +
Sbjct: 56 Y-KIVYRRYASLFFMVGVDDDENELAILEFIHLLVETMDKHFGNVCELDIMFHLEKAHFM 114
Query: 120 MDEMFIAGEIQTTSKKELLERIGQLDR 146
++EM + G I TSK +L I +D+
Sbjct: 115 LEEMVMNGCIVETSKANILSPIQLMDK 141
>At3g50860 [U] KOG0936 Clathrin adaptor complex small subunit
Length = 145
Score = 102 bits (253), Expect = 2e-22
Identities = 56/148 (37%), Positives = 87/148 (57%), Gaps = 8/148 (5%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIE----FS 58
++ ++ +N QG RL ++++ L + QE IR VF V+ R SNF+E F
Sbjct: 2 IKAVMMMNTQGKPRLAKFYDYLPVEK---QQELIRGVFSVLCSRPEN-VSNFLEIESLFG 57
Query: 59 KHTKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYL 118
++LVYK YA LYFV+ D + EL L I + VE LD F NVCELDI+FN+ K +
Sbjct: 58 PDSRLVYKHYATLYFVLVFDGSENELAMLDLIQVLVETLDKCFSNVCELDIVFNYSKMHA 117
Query: 119 VMDEMFIAGEIQTTSKKELLERIGQLDR 146
V+DE+ G++ TS E+++ + ++ +
Sbjct: 118 VLDEIVFGGQVLETSSAEVMKAVEEISK 145
>HsM5901934 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 144
Score = 96.7 bits (239), Expect = 1e-20
Identities = 54/146 (36%), Positives = 89/146 (59%), Gaps = 5/146 (3%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++F L +NKQG RL +++E +D ++ + +V K R + Q +FIE+ K K
Sbjct: 2 IKFFLMVNKQGQTRLSKYYEHVDINKRTLLET---EVIKSCLSRSNE-QCSFIEY-KDFK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
L+Y+ YA L+ V+GV+ + E+ IH FVEVLD +F V ELDI+FN K ++++DE
Sbjct: 57 LIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDE 116
Query: 123 MFIAGEIQTTSKKELLERIGQLDRLN 148
M + G I T++ +L + LD+++
Sbjct: 117 MVLNGCIVETNRARILAPLLILDKMS 142
>Hs4502861 [U] KOG0936 Clathrin adaptor complex small subunit
Length = 193
Score = 90.5 bits (223), Expect = 7e-19
Identities = 53/150 (35%), Positives = 83/150 (55%), Gaps = 9/150 (6%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFS---- 58
++ IL N G RL ++++ T Q+ IR+ F ++S+RD NF+E
Sbjct: 2 IKAILIFNNHGKPRLSKFYQPYSED---TQQQIIRETFHLVSKRDEN-VCNFLEGGLLIG 57
Query: 59 -KHTKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTY 117
KL+Y+ YA LYFV VD + EL L I +FVE LD F NVCELD++F+ K +
Sbjct: 58 GSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVH 117
Query: 118 LVMDEMFIAGEIQTTSKKELLERIGQLDRL 147
++ EM + G + T+ E++ +I ++L
Sbjct: 118 NILAEMVMGGMVLETNMNEIVTQIDAQNKL 147
>Hs5031581 [U] KOG0936 Clathrin adaptor complex small subunit
Length = 193
Score = 90.1 bits (222), Expect = 9e-19
Identities = 52/150 (34%), Positives = 83/150 (54%), Gaps = 9/150 (6%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSK--- 59
+Q IL N G RL+R++++ Q+ +R+ F ++ +RD NF+E
Sbjct: 2 IQAILVFNNHGKPRLVRFYQRFPEE---IQQQIVRETFHLVLKRDDNI-CNFLEGGSLIG 57
Query: 60 --HTKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTY 117
KL+Y+ YA LYFV VD + EL L I +FVE LD F NVCELD++F+ K +
Sbjct: 58 GSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVH 117
Query: 118 LVMDEMFIAGEIQTTSKKELLERIGQLDRL 147
++ E+ + G + T+ E++ +I +RL
Sbjct: 118 YILQEVVMGGMVLETNMNEIVAQIEAQNRL 147
>Hs11038643 [U] KOG0935 Clathrin adaptor complex small subunit
Length = 104
Score = 82.0 bits (201), Expect = 3e-16
Identities = 50/145 (34%), Positives = 75/145 (51%), Gaps = 43/145 (29%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++FIL N+ G RL +W+ + D + Q+ I +V V++ RD +KHT
Sbjct: 2 IRFILIQNRAGKTRLAKWYMQFDDDE---KQKLIEEVHAVVTVRD----------AKHTN 48
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
FVEVL+ +F NVCELD++FNFYK Y V+DE
Sbjct: 49 ------------------------------FVEVLNEYFHNVCELDLVFNFYKVYTVVDE 78
Query: 123 MFIAGEIQTTSKKELLERIGQLDRL 147
MF+AGEI+ TS+ ++L+++ L L
Sbjct: 79 MFLAGEIRETSQTKVLKQLLMLQSL 103
>SPAC30D11.05 [U] KOG0936 Clathrin adaptor complex small subunit
Length = 165
Score = 76.6 bits (187), Expect = 1e-14
Identities = 44/136 (32%), Positives = 74/136 (54%), Gaps = 7/136 (5%)
Query: 6 ILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIE---FSKHTK 62
+ N +G RL +++ +D S Q+ I ++ +S R NF+E + +
Sbjct: 5 VFIFNNKGKPRLTKFYTPIDES---IQQKLIGDIYAAVSTRPPTA-CNFLESNLIAGKNR 60
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDE 122
++Y+ YA LYFV VD+ + EL L I +FVE LD F NVCELD++F F + + ++ E
Sbjct: 61 IIYRQYATLYFVFVVDEGESELGILDLIQVFVEALDRCFNNVCELDLVFKFQEIHAILAE 120
Query: 123 MFIAGEIQTTSKKELL 138
+ G + T+ E++
Sbjct: 121 VVSGGLVLETNLNEIV 136
>7291698 [U] KOG0936 Clathrin adaptor complex small subunit
Length = 210
Score = 76.6 bits (187), Expect = 1e-14
Identities = 50/169 (29%), Positives = 85/169 (49%), Gaps = 28/169 (16%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSK--- 59
++ IL N G RL ++++ D S Q+ I++ F+++S+RD NF+E
Sbjct: 2 IKAILVFNNHGKPRLSKFYQYFDES---LQQQIIKETFQLVSKRDDN-VCNFLEGGSLIG 57
Query: 60 --HTKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNF---- 113
KL+Y+ YA LYFV VD + EL L I +FVE LD F NVCELD++F+
Sbjct: 58 GSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHADAVH 117
Query: 114 ---------------YKTYLVMDEMFIAGEIQTTSKKELLERIGQLDRL 147
+ + + E+ + G + T+ +++ RI + +++
Sbjct: 118 HILSGWESYFGNPFRFSYHEFVSELVMGGMVLQTNMNDIMARIEEQNKI 166
>Hs21361394 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 159
Score = 73.6 bits (179), Expect = 9e-14
Identities = 42/109 (38%), Positives = 65/109 (59%), Gaps = 5/109 (4%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEFSKHTK 62
++F L +NKQG RL +++E +D ++ + +V K R + Q +FIE+ K K
Sbjct: 2 IKFFLMVNKQGQTRLSKYYEHVDINKRTLLET---EVIKSCLSRSNE-QCSFIEY-KDFK 56
Query: 63 LVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILF 111
L+Y+ YA L+ V+GV+ + E+ IH FVEVLD +F V ELD+ F
Sbjct: 57 LIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDVSF 105
>YJL024c [U] KOG0936 Clathrin adaptor complex small subunit
Length = 194
Score = 72.8 bits (177), Expect = 2e-13
Identities = 46/160 (28%), Positives = 83/160 (51%), Gaps = 19/160 (11%)
Query: 3 VQFILCLNKQGIVRLLRWFEKLDTSQYATHQEYIRQVFKVISQRDHRRQSNFIEF----- 57
+ +L NK+ RL++++ +D + + + QV+++ISQR+ QS+F+
Sbjct: 2 IHAVLIFNKKCQPRLVKFYTPVDLPK---QKLLLEQVYELISQRNSDFQSSFLVTPPSLL 58
Query: 58 -----------SKHTKLVYKGYAGLYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCE 106
++ +++YK YA LYF VD Q+ EL L I FVE LD F V E
Sbjct: 59 LSNENNNDEVNNEDIQIIYKNYATLYFTFIVDDQESELAILDLIQTFVESLDRCFTEVNE 118
Query: 107 LDILFNFYKTYLVMDEMFIAGEIQTTSKKELLERIGQLDR 146
LD++FN+ V++E+ G + T+ ++ + +L++
Sbjct: 119 LDLIFNWQTLESVLEEIVQGGMVIETNVNRIVASVDELNK 158
>Hs20539280 [U] KOG0934 Clathrin adaptor complex small subunit
Length = 185
Score = 60.1 bits (144), Expect = 1e-09
Identities = 27/69 (39%), Positives = 45/69 (65%), Gaps = 5/69 (7%)
Query: 71 LYFVMGVDKQDEELIYLSQIHLFVEVLDSFFGNVCELDILFNFYKTYLVMDEMFIAGEIQ 130
L+ VMG EL L IH ++E+L+ +FG+VCELD++FNF + Y ++DE F+ G++
Sbjct: 114 LHGVMG-----NELTALETIHHYMELLNKYFGSVCELDVVFNFEEVYFILDEFFLEGKLG 168
Query: 131 TTSKKELLE 139
+K + +
Sbjct: 169 NLQEKAIAQ 177
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.328 0.143 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,326,270
Number of Sequences: 60738
Number of extensions: 327089
Number of successful extensions: 1037
Number of sequences better than 1.0e-05: 28
Number of HSP's better than 0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 988
Number of HSP's gapped (non-prelim): 29
length of query: 148
length of database: 30,389,216
effective HSP length: 96
effective length of query: 52
effective length of database: 24,558,368
effective search space: 1277035136
effective search space used: 1277035136
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)