ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1634 good F KOG3327 Nucleotide transport and metabolism Thymidylate kinase/adenylate kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1634 584164 583541 -208
(208 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR057w [F] KOG3327 Thymidylate kinase/adenylate kinase 221 7e-58
At5g59440 [F] KOG3327 Thymidylate kinase/adenylate kinase 166 3e-41
SPCC70.07c [F] KOG3327 Thymidylate kinase/adenylate kinase 160 1e-39
Hs22042064 [F] KOG3327 Thymidylate kinase/adenylate kinase 145 4e-35
Hs6912340 [F] KOG3327 Thymidylate kinase/adenylate kinase 140 9e-34
7302676 [F] KOG3327 Thymidylate kinase/adenylate kinase 126 2e-29
CE03571 [F] KOG3327 Thymidylate kinase/adenylate kinase 124 1e-28
ECU04g1220 [F] KOG3327 Thymidylate kinase/adenylate kinase 102 5e-22
>YJR057w [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 216
Score = 221 bits (562), Expect = 7e-58
Identities = 112/207 (54%), Positives = 149/207 (71%), Gaps = 5/207 (2%)
Query: 1 MVRGKLILIEGLDRTGKSTQCENVVNALGNDAVLIKFPDRTTKIGQLINQYLTDKDFELP 60
M RGKLILIEGLDRTGK+TQC + L + L+KFP+R+T+IG LIN+YLTD F+L
Sbjct: 2 MGRGKLILIEGLDRTGKTTQCNILYKKLQPNCKLLKFPERSTRIGGLINEYLTDDSFQLS 61
Query: 61 AQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAYSAAKGIQGMDISWCFNPDK 120
Q+IHLLFSANRWE+ ++I L GK++V+DRYVYSGVAYSAAKG GMD+ WC PD
Sbjct: 62 DQAIHLLFSANRWEIVDKIKKDLLEGKNIVMDRYVYSGVAYSAAKGTNGMDLDWCLQPDV 121
Query: 121 GLLKPDLTLFFSNS--SNMRDREGFGEERYEKVEFQRQVRDTFFNVFD-QIK--DSNRIV 175
GLLKPDLTLF S N ++ GFG+ERYE V+FQ +V+ TF + D +I+ D + +
Sbjct: 122 GLLKPDLTLFLSTQDVDNNAEKSGFGDERYETVKFQEKVKQTFMKLLDKEIRKGDESITI 181
Query: 176 IDVSDKSIDEVFSEIKPLIHDVINKEL 202
+DV++K I EV + I ++ V++ +
Sbjct: 182 VDVTNKGIQEVEALIWQIVEPVLSTHI 208
>At5g59440 [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 224
Score = 166 bits (419), Expect = 3e-41
Identities = 91/202 (45%), Positives = 135/202 (66%), Gaps = 13/202 (6%)
Query: 3 RGKLILIEGLDRTGKSTQCENVV---NALGNDAVLIKFPDRTTKIGQLINQYLTDKDFEL 59
RG LI++EGLDR+GKSTQC ++ N LG+ L +FPDR T +GQ+I+ YL++K +L
Sbjct: 19 RGALIVLEGLDRSGKSTQCAKLLSFLNGLGHPTELWRFPDRETSVGQMISAYLSNKS-QL 77
Query: 60 PAQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAYSAAKGIQGMDISWCFNPD 119
+IHLLFSANRWE + + LK G +++DRY YSGVA+S+AK G+DI WC P+
Sbjct: 78 DDHTIHLLFSANRWEKRSLMEEKLKTGTTLIVDRYSYSGVAFSSAK---GLDIEWCKAPE 134
Query: 120 KGLLKPDLTLFFSNS-SNMRDREGFGEERYEKVEFQRQVRDTFFNVFDQIKDSNRIVIDV 178
GLL PD L+ S +R G+G+ERYE+VEFQ++V D + + DS+ +I+
Sbjct: 135 IGLLAPDSVLYLDISPERAAERGGYGDERYERVEFQKKVAD----FYQTLGDSSWKIINA 190
Query: 179 SDKSIDEVFSEIKPLIHDVINK 200
SD +++EV +I+ ++ D + +
Sbjct: 191 SD-AMEEVEKKIQQVVLDQVKE 211
>SPCC70.07c [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 210
Score = 160 bits (404), Expect = 1e-39
Identities = 91/201 (45%), Positives = 130/201 (64%), Gaps = 11/201 (5%)
Query: 3 RGKLILIEGLDRTGKSTQCENVVNALGND---AVLIKFPDRTTKIGQLINQYLTDKDFEL 59
RG+LI+IEGLDR+GKSTQC+ +V+ L + A L KFPDRTT IG+ I+ YL + +L
Sbjct: 6 RGRLIVIEGLDRSGKSTQCQLLVDKLISQHEKAELFKFPDRTTAIGKKIDDYLKES-VQL 64
Query: 60 PAQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAYSAAKGIQGMDISWCFNPD 119
Q IHLLFSANRWE + I+ + G +LDRY +SG+A+SAAK G+D WC +PD
Sbjct: 65 NDQVIHLLFSANRWETIQYIYEQINKGVTCILDRYAFSGIAFSAAK---GLDWEWCKSPD 121
Query: 120 KGLLKPDLTLFFSNSSNMRDREG-FGEERYEKVEFQRQVRDTFFNVFDQIKDSNR--IVI 176
+GL +PDL +F + + G +GEERYEK+E Q +V F + + ++ I +
Sbjct: 122 RGLPRPDLVIFLNVDPRIAATRGQYGEERYEKIEMQEKVLKNFQRLQKEFREEGLEFITL 181
Query: 177 DVSDKSIDEVFSEIKPLIHDV 197
D S S+++V S+I L+ +V
Sbjct: 182 DAS-SSLEDVHSQIVDLVSNV 201
>Hs22042064 [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 212
Score = 145 bits (366), Expect = 4e-35
Identities = 92/212 (43%), Positives = 126/212 (59%), Gaps = 17/212 (8%)
Query: 3 RGKLILIEGLDRTGKSTQCENVVNAL---GNDAVLIKFPDRTTKIGQLINQYLTDKDFEL 59
RG LI++EG+DR GKSTQ +V AL G+ A L++FP+R+T+IG+L++ YL K ++
Sbjct: 5 RGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKS-DV 63
Query: 60 PAQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAYSAAKGIQGMDISWCFNPD 119
S+HLLFSANRWE I L G +V+DRY +SGVA++ AK + + WC PD
Sbjct: 64 EDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAK--ENFSLDWCKQPD 121
Query: 120 KGLLKPDLTLFFS-NSSNMRDREGFGEERYEKVEFQRQVRDTFFNVFDQIKDS--NRIVI 176
GL KPDL LF ++ R FG ERYE FQ + F + +KD+ N ++
Sbjct: 122 VGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL---MKDTTLNWKMV 178
Query: 177 DVSDKSIDEVFSEIKPLIHDVI----NKELGE 204
D S KSI+ V +I+ L D I K LGE
Sbjct: 179 DAS-KSIEAVHEDIRVLSEDAIRTATEKPLGE 209
>Hs6912340 [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 211
Score = 140 bits (354), Expect = 9e-34
Identities = 89/211 (42%), Positives = 123/211 (58%), Gaps = 16/211 (7%)
Query: 3 RGKLILIEGLDRTGKSTQCENVVNAL--GNDAVLIKFPDRTTKIGQLINQYLTDKDFELP 60
RG LI++EG+DR GKSTQ +V AL G L++FP+R+T+IG+L++ YL K ++
Sbjct: 5 RGALIVLEGVDRAGKSTQSRKLVEALSRGPPPELLRFPERSTEIGKLLSSYLQKKS-DVE 63
Query: 61 AQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAYSAAKGIQGMDISWCFNPDK 120
S+HLLFSANRWE I L G +V+DRY +SGVA++ AK + + WC PD
Sbjct: 64 DHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAK--ENFSLDWCKQPDV 121
Query: 121 GLLKPDLTLFFS-NSSNMRDREGFGEERYEKVEFQRQVRDTFFNVFDQIKDS--NRIVID 177
GL KPDL LF ++ R FG ERYE FQ + F + +KD+ N ++D
Sbjct: 122 GLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQL---MKDTTLNWKMVD 178
Query: 178 VSDKSIDEVFSEIKPLIHDVI----NKELGE 204
S K ++ V E++ L D I K LGE
Sbjct: 179 AS-KRLEAVHEELRVLSEDAIRTATEKPLGE 208
>7302676 [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 171
Score = 126 bits (316), Expect = 2e-29
Identities = 66/167 (39%), Positives = 106/167 (62%), Gaps = 7/167 (4%)
Query: 35 IKFPDRTTKIGQLINQYLTDKDFELPAQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRY 94
+ FP+R++ IGQ+IN YLT+ +LP + IHL+FSANRWE ++ L G +V+DRY
Sbjct: 1 MNFPERSSSIGQVINSYLTNSK-DLPDEVIHLMFSANRWEHINQVKEKLLEGTTLVVDRY 59
Query: 95 VYSGVAYSAAKGIQGMDISWCFNPDKGLLKPDLTLFFSNSSN-MRDREGFGEERYEKVEF 153
+SGVAYSAAK G+D WC+ P++GL+KPD + N + R +G+ERYEKVEF
Sbjct: 60 SFSGVAYSAAK---GLDFDWCYAPERGLIKPDAVFYLRAPPNDLTHRGQYGKERYEKVEF 116
Query: 154 QRQVRDTFFNVFDQIKDSNRIVIDVSDKSIDEVFSEIKPLIHDVINK 200
Q +V + F + K+ + + +S++++ ++I + +++ K
Sbjct: 117 QGRVAEVFNRICS--KEGSYFHQFDARQSVEDLHAQIASITEELLPK 161
>CE03571 [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 218
Score = 124 bits (310), Expect = 1e-28
Identities = 74/168 (44%), Positives = 99/168 (58%), Gaps = 17/168 (10%)
Query: 3 RGKLILIEGLDRTGKSTQCENVVNALGN------------DAVLIKFPDRTTKIGQLINQ 50
RG LI+ EGLDR+GKSTQ + +V ++ AVL FPDR++ IG+LI+Q
Sbjct: 7 RGLLIVFEGLDRSGKSTQAKRLVESINKKSTESGDASSSPSAVLQAFPDRSSSIGKLIDQ 66
Query: 51 YLTDKDFELPAQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAYSAAKGIQGM 110
YL K+ ++ ++HLLFSA+R+ + I + G V+ DRY YSGVAYS AKG+
Sbjct: 67 YLR-KEIDMDEHALHLLFSADRFSKNQMIRDNIAKGIDVICDRYCYSGVAYSLAKGLPE- 124
Query: 111 DISWCFNPDKGLLKPDLTLFFSNSSNM-RDREGFGEERYEKVEFQRQV 157
W + D GL KPD LFF S + R GFGEER E Q++V
Sbjct: 125 --QWVRSSDVGLPKPDAVLFFDVSPEVAAQRGGFGEERLETATIQQKV 170
>ECU04g1220 [F] KOG3327 Thymidylate kinase/adenylate kinase
Length = 191
Score = 102 bits (253), Expect = 5e-22
Identities = 65/180 (36%), Positives = 105/180 (58%), Gaps = 10/180 (5%)
Query: 1 MVRGKLILIEGLDRTGKSTQCENVVNALGN--DAVLIKFPDRTTKIGQLINQYLTDKDFE 58
M +GK ++ EGLDR+GK+T ++ +L I+FP+R+ +G++I+ YL K
Sbjct: 1 MSKGKFVVFEGLDRSGKTTIVGSLYESLLPIVPTSKIRFPNRSGPVGKIIDGYL-QKKTN 59
Query: 59 LPAQSIHLLFSANRWELKEEIHSMLKAGKHVVLDRYVYSGVAYSAAKGIQGMDISWCFNP 118
L +++IHLLFSA+R+E + I L+ ++ DRY SG+AYS AK G+ + WC
Sbjct: 60 LESETIHLLFSADRYEHRLMIEE-LRRDTIILCDRYSMSGIAYSVAK---GLSLDWCIAS 115
Query: 119 DKGLLKPDLTLFFS-NSSNMRDREGFGEERYEKVEFQRQVRDTFFNVFDQIKDSNRIVID 177
+ L KPDLT+F + R+GFG E ++ V F ++V + + K+ N +V+D
Sbjct: 116 EALLPKPDLTIFIDVPMDEICRRKGFGTEIHDTVPFLKKVLSAYQALLK--KEENTLVVD 173
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.140 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,229,912
Number of Sequences: 60738
Number of extensions: 515765
Number of successful extensions: 1433
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1397
Number of HSP's gapped (non-prelim): 8
length of query: 208
length of database: 30,389,216
effective HSP length: 102
effective length of query: 106
effective length of database: 24,193,940
effective search space: 2564557640
effective search space used: 2564557640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)