ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1647 good TZ KOG4203 Cytoskeleton Armadillo/beta-Catenin/plakoglobin
r_klactII1647 good TZ KOG4203 Signal transduction mechanisms Armadillo/beta-Catenin/plakoglobin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1647 588821 589447 209
(209 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR020c [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 181 6e-46
At3g27190 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 70 3e-12
YNR012w [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 67 1e-11
At1g55810 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 65 5e-11
At5g40870 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 64 1e-10
At3g27440 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 64 2e-10
Hs18699734 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 57 1e-08
CE20700 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 57 2e-08
CE05666 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 57 2e-08
Hs8923487 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 56 3e-08
7301141 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 56 4e-08
7302796 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 54 1e-07
Hs13899253 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin 50 2e-06
>YDR020c [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 232
Score = 181 bits (459), Expect = 6e-46
Identities = 98/223 (43%), Positives = 151/223 (66%), Gaps = 17/223 (7%)
Query: 4 RIVINIAGGHYAGALQTTKEIESKLLGIFKH-DVRVIDLDERAIAP-RQYSDKDYDFESI 61
RIVI+I GGH G ++++ ++ ++RVI+LD + Y++ DYDF++I
Sbjct: 10 RIVISIGGGHATGVGAIALDLQNTFKSLYNSINIRVINLDNMIEGNIKSYNNNDYDFDNI 69
Query: 62 ---IHEIKNVSSKGDLV---------IILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLI 109
++E V+S+ D++ +I+VCGCY+L+D ++ ++S LKVF+DSD DKRLI
Sbjct: 70 LNLVYEKHAVTSQNDMIQHDYEDPIDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLI 129
Query: 110 NLIQQKHVITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIPSANDALGTAIIVDGI 169
+LI++K+V + + L I+ YMDHLRPEM YI+P++T AD+IIPS N+ LG A++VDGI
Sbjct: 130 SLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPSTNENLGRAVLVDGI 189
Query: 170 VKVVE--QYQGGGSNDTKKLFPQL-DFNLERMELQKERYYELS 209
VK +E + Q G+N K+ P+L DF E M+L+K+RYY+LS
Sbjct: 190 VKAIEDTKSQIEGNNTNNKIRPRLWDFEAETMDLEKDRYYDLS 232
>At3g27190 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 483
Score = 69.7 bits (169), Expect = 3e-12
Identities = 53/194 (27%), Positives = 95/194 (48%), Gaps = 12/194 (6%)
Query: 3 HRIVINIAGGHYAGALQTTKEIESKLLGIFKHD-----VRVIDLDERAIAPRQYSDKDYD 57
HRIV+ Y G T++E+E F H +++ + + + Y YD
Sbjct: 89 HRIVLVNQDSFYRGL--TSEELEHVQEYNFDHPDAFDTEQLLHCVDILKSGQPYQIPIYD 146
Query: 58 FESIIHEIKNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQKHV 117
F++ ++ +I++ G DS++ DL ++K+FVD+D D RL I++ V
Sbjct: 147 FKTHQRKVDAFRQVNACDVIILEGILVFHDSRVRDLMNMKIFVDTDADVRLARRIRRDTV 206
Query: 118 ITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIPSANDALGTAIIVDGIVKVVEQYQ 177
G D++S + Y ++P +++ PSK AD+IIP D + VD IV+ + +
Sbjct: 207 ERGRDVDSVLEQYAKFVKPAFDDFVLPSKKYADVIIPRGGD---NHVAVDLIVQHI--HT 261
Query: 178 GGGSNDTKKLFPQL 191
G +D K++P +
Sbjct: 262 KLGQHDLCKIYPNV 275
>YNR012w [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 501
Score = 67.4 bits (163), Expect = 1e-11
Identities = 37/110 (33%), Positives = 62/110 (55%), Gaps = 2/110 (1%)
Query: 66 KNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQKHVITGDDLES 125
KN+ G V+++ G Y+L+D +L DL LK++VD+D D L + + V G DL+
Sbjct: 152 KNIVIYGASVVVIE-GIYALYDRRLLDLMDLKIYVDADLDVCLARRLSRDIVSRGRDLDG 210
Query: 126 CISYYMDHLRPEMINYIDPSKTKADIIIPSAND-ALGTAIIVDGIVKVVE 174
CI + ++P + ++ P+ AD IIPS +D A +I++ I +E
Sbjct: 211 CIQQWEKFVKPNAVKFVKPTMKNADAIIPSMSDNATAVNLIINHIKSKLE 260
>At1g55810 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 466
Score = 65.5 bits (158), Expect = 5e-11
Identities = 41/137 (29%), Positives = 72/137 (51%), Gaps = 5/137 (3%)
Query: 55 DYDFESIIHEIKNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQ 114
+YDF+S + + +I++ G D ++ DL ++K+FVD+D D RL I++
Sbjct: 126 NYDFKSYKNNVFPPRRVNPSDVIILEGILIFHDPRVRDLMNMKIFVDADADVRLARRIKR 185
Query: 115 KHVITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIPSANDALGTAIIVDGIVKVVE 174
V G D+ + + Y ++P ++I P+K ADIIIP D + +D IV+ +
Sbjct: 186 DTVEKGRDIATVLDQYSKFVKPAFEDFILPTKKYADIIIPRGGD---NHVAIDLIVQHI- 241
Query: 175 QYQGGGSNDTKKLFPQL 191
+ G +D K++P L
Sbjct: 242 -HTKLGQHDLCKIYPNL 257
>At5g40870 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 486
Score = 64.3 bits (155), Expect = 1e-10
Identities = 50/194 (25%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 3 HRIVINIAGGHYAGALQTTKEIESKLLGIFKHD-----VRVIDLDERAIAPRQYSDKDYD 57
HR+V+ Y G T++E++ F H +++ E + + Y YD
Sbjct: 89 HRVVLVNQDSFYRGL--TSEELQRVQEYNFDHPDAFDTEQLLHCAETLKSGQPYQVPIYD 146
Query: 58 FESIIHEIKNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQKHV 117
F++ +I++ G DS++ +L ++K+FVD+D D RL I++ V
Sbjct: 147 FKTHQRRSDTFRQVNASDVIILEGILVFHDSRVRNLMNMKIFVDTDADVRLARRIRRDTV 206
Query: 118 ITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIPSANDALGTAIIVDGIVKVVEQYQ 177
G D+ S + Y ++P +++ PSK AD+IIP D + VD I + + +
Sbjct: 207 ERGRDVNSVLEQYAKFVKPAFDDFVLPSKKYADVIIPRGGD---NHVAVDLITQHI--HT 261
Query: 178 GGGSNDTKKLFPQL 191
G +D K++P +
Sbjct: 262 KLGQHDLCKIYPNV 275
>At3g27440 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 465
Score = 63.5 bits (153), Expect = 2e-10
Identities = 40/106 (37%), Positives = 59/106 (54%), Gaps = 7/106 (6%)
Query: 56 YDFESIIHEIKNVSSK---GDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLI 112
YDF+ IH+ SS GD++I+ G L D ++ DL ++K+FVD+D D RL I
Sbjct: 112 YDFK--IHQSIESSSPVNPGDVIILE--GILVLNDPRVRDLMNMKIFVDTDADVRLSRRI 167
Query: 113 QQKHVITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIPSAND 158
Q+ V G ++++ + Y ++P YI PS ADIIIP D
Sbjct: 168 QRDTVERGRNIQNVLEQYTKFVKPSFDEYIQPSMKYADIIIPRGGD 213
>Hs18699734 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 261
Score = 57.4 bits (137), Expect = 1e-08
Identities = 32/105 (30%), Positives = 56/105 (52%), Gaps = 3/105 (2%)
Query: 76 IILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQKHVITGDDLESCISYYMDHLR 135
++L G + + ++ DL +K+FVD+D D RL + + G DLE +S Y+ ++
Sbjct: 131 VVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVK 190
Query: 136 PEMINYIDPSKTKADIIIPSANDALGTAIIVDGIVKVVEQYQGGG 180
P + P+K AD+IIP D L + ++ IV+ ++ GG
Sbjct: 191 PAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGG 232
>CE20700 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 555
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/122 (29%), Positives = 60/122 (48%), Gaps = 3/122 (2%)
Query: 56 YDFESIIHEIKNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQK 115
YDF + + + G V+I G + D ++ +L +KVFVD+DGD RL I +
Sbjct: 189 YDFNTHSRDPNSKMMYGADVLIFE-GILAFHDERIKNLMDMKVFVDTDGDLRLARRIVRD 247
Query: 116 HVITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIP--SANDALGTAIIVDGIVKVV 173
G D++ + Y ++P YI P AD+I+P ND I+ + + ++V
Sbjct: 248 VTDRGRDIDGIMEQYFTFVKPAFDKYIAPCMDSADLIVPRGGENDVAIDMIVQNVMAQLV 307
Query: 174 EQ 175
E+
Sbjct: 308 ER 309
>CE05666 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 515
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/122 (29%), Positives = 60/122 (48%), Gaps = 3/122 (2%)
Query: 56 YDFESIIHEIKNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQK 115
YDF + + + G V+I G + D ++ +L +KVFVD+DGD RL I +
Sbjct: 149 YDFNTHSRDPNSKMMYGADVLIFE-GILAFHDERIKNLMDMKVFVDTDGDLRLARRIVRD 207
Query: 116 HVITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIP--SANDALGTAIIVDGIVKVV 173
G D++ + Y ++P YI P AD+I+P ND I+ + + ++V
Sbjct: 208 VTDRGRDIDGIMEQYFTFVKPAFDKYIAPCMDSADLIVPRGGENDVAIDMIVQNVMAQLV 267
Query: 174 EQ 175
E+
Sbjct: 268 ER 269
>Hs8923487 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 548
Score = 56.2 bits (134), Expect = 3e-08
Identities = 30/98 (30%), Positives = 52/98 (52%), Gaps = 3/98 (3%)
Query: 76 IILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQKHVITGDDLESCISYYMDHLR 135
+I+ G + D L +L +K+FVD+D D RL+ +++ G D+E I Y ++
Sbjct: 202 VIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVK 261
Query: 136 PEMINYIDPSKTKADIIIPSANDALGTAIIVDGIVKVV 173
P YI P+ ADI++P + G + ++ IV+ V
Sbjct: 262 PSFDQYIQPTMRLADIVVPRGS---GNTVAINLIVQHV 296
>7301141 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 260
Score = 55.8 bits (133), Expect = 4e-08
Identities = 34/133 (25%), Positives = 68/133 (50%), Gaps = 1/133 (0%)
Query: 56 YDFESIIHEIKNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQK 115
YD+ + + +NV ++L G + K+ +L +K+FVD+D D RL + +
Sbjct: 119 YDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRD 178
Query: 116 HVITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIP-SANDALGTAIIVDGIVKVVE 174
G DL++ ++ YM ++P + P+K AD+IIP A++ + +IV I +++
Sbjct: 179 INERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRGADNTVAIDLIVHHIGEILA 238
Query: 175 QYQGGGSNDTKKL 187
++T ++
Sbjct: 239 TTNSAQHSNTVRV 251
>7302796 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 614
Score = 54.3 bits (129), Expect = 1e-07
Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Query: 56 YDFESIIHEIKNVSSKGDLVIILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQK 115
Y+F + E + + G VII G + ++ L +K+FVD+D D RL +++
Sbjct: 259 YNFVTHGRESQTKTMYGANVIIFE-GILTFHSPEVLKLLDMKIFVDTDPDIRLARRLRRD 317
Query: 116 HVITGDDLESCISYYMDHLRPEMINYIDPSKTKADIIIPSAND 158
G DL+ + Y++ ++P NYI P+ ADII+P D
Sbjct: 318 ISQRGRDLKGVLKQYLNMVKPSYCNYIAPTMAHADIIVPRGGD 360
>Hs13899253 [TZ] KOG4203 Armadillo/beta-Catenin/plakoglobin
Length = 277
Score = 50.1 bits (118), Expect = 2e-06
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 6/112 (5%)
Query: 76 IILVCGCYSLFDSKLCDLSSLKVFVDSDGDKRLINLIQQKHVITGDDLESCISYYMDHLR 135
++L G + ++ D+ L++FVD+D D RL + + V G DLE ++ Y ++
Sbjct: 134 VVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVL-RDVRRGRDLEQILTQYTTFVK 192
Query: 136 PEMINYIDPSKTKADIIIP-SANDALGTAIIVDGIVKVVE----QYQGGGSN 182
P + P+K AD+IIP ++ + +IV I ++ ++ GGSN
Sbjct: 193 PAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSN 244
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.141 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,724,192
Number of Sequences: 60738
Number of extensions: 531143
Number of successful extensions: 1346
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1330
Number of HSP's gapped (non-prelim): 13
length of query: 209
length of database: 30,389,216
effective HSP length: 102
effective length of query: 107
effective length of database: 24,193,940
effective search space: 2588751580
effective search space used: 2588751580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)