ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1738 good OKT KOG1499 Posttranslational modification, protein turnover, chaperones Protein arginine N-methyltransferase PRMT1 and related enzymes
r_klactII1738 good OKT KOG1499 Signal transduction mechanisms Protein arginine N-methyltransferase PRMT1 and related enzymes
r_klactII1738 good OKT KOG1499 Transcription Protein arginine N-methyltransferase PRMT1 and related enzymes
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1738 618368 619411 348
(348 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR034c [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 567 e-162
SPAC890.07c [OKT] KOG1499 Protein arginine N-methyltransferase P... 387 e-107
7299364 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 343 2e-94
At4g29510 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 330 2e-90
HsM9789979 [OKT] KOG1499 Protein arginine N-methyltransferase PR... 321 9e-88
Hs21314692 [OKT] KOG1499 Protein arginine N-methyltransferase PR... 321 9e-88
At2g19670 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 321 1e-87
CE23297 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 320 3e-87
Hs4504497 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 264 2e-70
7299975 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 253 4e-67
SPBPI055 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT... 240 3e-63
SPBC8D2.10c [OKT] KOG1499 Protein arginine N-methyltransferase P... 240 3e-63
7295728 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 239 3e-63
7299824 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 220 3e-57
At3g20020 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 217 2e-56
Hs4504495 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 196 6e-50
At3g12270 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 194 1e-49
Hs8922515 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 191 1e-48
Hs18601084 [OK] KOG1500 Protein arginine N-methyltransferase CARM1 172 7e-43
Hs14780868 [OKT] KOG1499 Protein arginine N-methyltransferase PR... 171 2e-42
7297802 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 159 4e-39
7299276 [OK] KOG1500 Protein arginine N-methyltransferase CARM1 158 1e-38
At1g04870 [OKT] KOG1499 Protein arginine N-methyltransferase PRM... 156 4e-38
At3g06930 [OK] KOG1500 Protein arginine N-methyltransferase CARM1 154 2e-37
Hs22061930 [OKT] KOG1499 Protein arginine N-methyltransferase PR... 149 6e-36
At5g49020 [OK] KOG1500 Protein arginine N-methyltransferase CARM1 144 2e-34
7299823 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 142 9e-34
Hs18571812 [OK] KOG1500 Protein arginine N-methyltransferase CARM1 69 1e-11
Hs9506615 [R] KOG1501 Arginine N-methyltransferase 67 4e-11
7291527 [R] KOG1501 Arginine N-methyltransferase 59 1e-08
CE16546 [R] KOG1501 Arginine N-methyltransferase 55 2e-07
CE18281 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1... 50 6e-06
>YBR034c [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 348
Score = 567 bits (1462), Expect = e-162
Identities = 272/348 (78%), Positives = 303/348 (86%)
Query: 1 MSKTDVTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGK 60
MSKT V DSAT+K +L+E EQHYF SYDH+GIHEEMLQDTVRTLSYRNAI QNKD FK K
Sbjct: 1 MSKTAVKDSATEKTKLSESEQHYFNSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDK 60
Query: 61 VVLDVGCGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVV 120
+VLDVGCGTGILSMFAAK+GAKHVIGVDMSSIIEMAK++VELNG SDKITLLRGKLEDV
Sbjct: 61 IVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVH 120
Query: 121 LPYKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKG 180
LP+ KVDIIISEWMGYFLLYESM+DTVLYARD+YLVEGGLIFPDKCSIH+AGLEDS+YK
Sbjct: 121 LPFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKD 180
Query: 181 EKLNFWQDVYGFDYSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSK 240
EKLN+WQDVYGFDYSPF+PLV EP+VDTVE ++VNTT KLIEFDLNTV I DLAF S
Sbjct: 181 EKLNYWQDVYGFDYSPFVPLVLHEPIVDTVERNNVNTTSDKLIEFDLNTVKISDLAFKSN 240
Query: 241 FKLQAKRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEAN 300
FKL AKRQD ING+++WFDI FPAPKG +PV FSTG HA YTHWKQT+FY DDL+ E
Sbjct: 241 FKLTAKRQDMINGIVTWFDIVFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETG 300
Query: 301 DILEGELTCLPNKDNNRDLDIKIVYNFKASGPDGKERSRKGTNTYLMH 348
D +EGEL C PN+ NNRDL+IKI Y F+++G DG RSRK +YLMH
Sbjct: 301 DTIEGELVCSPNEKNNRDLNIKISYKFESNGIDGNSRSRKNEGSYLMH 348
>SPAC890.07c [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 339
Score = 387 bits (995), Expect = e-107
Identities = 186/314 (59%), Positives = 233/314 (73%), Gaps = 2/314 (0%)
Query: 20 EQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKN 79
+ +YF SY H+GIHEEML+D VRTLSYR+AI QN F+ K+VLDVGCGTGILSMF A+
Sbjct: 16 KDYYFDSYSHWGIHEEMLKDDVRTLSYRDAIMQNPHLFRDKIVLDVGCGTGILSMFCARA 75
Query: 80 GAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLL 139
GAKHV GVDMS II A QIVE+N LSD+ITL++GK+E++ LP +KVDII+SEWMGYFLL
Sbjct: 76 GAKHVYGVDMSEIIHKAVQIVEVNKLSDRITLIQGKMEEIQLPVEKVDIIVSEWMGYFLL 135
Query: 140 YESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFIP 199
YESMLDTVL ARD YL GL+FPD+ I +A +ED+ YK EK+ FW DVYGFD+SP
Sbjct: 136 YESMLDTVLVARDRYLAPDGLLFPDRAQIQLAAIEDADYKSEKIGFWDDVYGFDFSPIKK 195
Query: 200 LVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWFD 259
V +EPLVDTV+ +VNT C +++ DL TV DLAF S F++ A R DF++ ++WFD
Sbjct: 196 DVWKEPLVDTVDRIAVNTNSCVILDLDLKTVKKEDLAFSSPFEITATRNDFVHAFLAWFD 255
Query: 260 IEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDL 319
IEF A +KP+ FSTG + YTHWKQTVFY DL +A + + G +TC P + N+R+L
Sbjct: 256 IEFSA--CHKPIKFSTGPFSRYTHWKQTVFYTHKDLTVKAGEYIRGTITCKPAEGNHREL 313
Query: 320 DIKIVYNFKASGPD 333
DI I Y F P+
Sbjct: 314 DIDISYTFNPREPN 327
>7299364 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 376
Score = 343 bits (880), Expect = 2e-94
Identities = 179/328 (54%), Positives = 228/328 (68%), Gaps = 9/328 (2%)
Query: 22 HYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGA 81
+YF SY HFGIHEEML+D VRT++YRNA+ NK F+GK VLDVGCGTGILSMFAAK GA
Sbjct: 55 YYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGA 114
Query: 82 KHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLP--YKKVDIIISEWMGYFLL 139
VI VD S+IIE A+Q+V N L D IT+++GK+E++ LP + VDIIISEWMGY L
Sbjct: 115 AQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLF 174
Query: 140 YESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFIP 199
YESMLDTVLYARD +L + G++FPD+ +++I +ED +YK EK+N+W DVYGFD S
Sbjct: 175 YESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRK 234
Query: 200 LVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWFD 259
+ EPLVD V+ V +T C + E DL TV DL F SKF L KR DF+ L+++F+
Sbjct: 235 VAVTEPLVDVVDPKQVVSTSCMVKEVDLYTVQKADLNFSSKFSLCIKRNDFVQALVTYFN 294
Query: 260 IEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDL 319
IEF K +K + FST +TYTHWKQTVFYL+D + + N+ + G PN+ NNRDL
Sbjct: 295 IEF--TKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDL 352
Query: 320 DIKIVYNFKASGPDGKERSRKGTNTYLM 347
D I NFK G+ + +NTY M
Sbjct: 353 DFVIDINFK-----GELSQIQESNTYRM 375
>At4g29510 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 390
Score = 330 bits (846), Expect = 2e-90
Identities = 165/322 (51%), Positives = 221/322 (68%), Gaps = 9/322 (2%)
Query: 5 DVTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLD 64
+VTD T +YF SY HFGIHEEML+D VRT +Y+N I QNK K K+VLD
Sbjct: 61 EVTDDTTSA-------DYYFDSYSHFGIHEEMLKDVVRTKTYQNVIYQNKFLIKDKIVLD 113
Query: 65 VGCGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYK 124
VG GTGILS+F AK GA HV V+ S + +MAK+IV+ NG SD IT+L+GK+E++ LP
Sbjct: 114 VGAGTGILSLFCAKAGAAHVYAVECSQMADMAKEIVKANGFSDVITVLKGKIEEIELPTP 173
Query: 125 KVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLN 184
KVD+IISEWMGYFLL+E+MLD+VLYARD +LVEGG++ PDK S+H+ +EDS+YK +K+
Sbjct: 174 KVDVIISEWMGYFLLFENMLDSVLYARDKWLVEGGVVLPDKASLHLTAIEDSEYKEDKIE 233
Query: 185 FWQDVYGFDYSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQ 244
FW VYGFD S EPLVDTV+ + + T L D++ ++ D +F + FKL
Sbjct: 234 FWNSVYGFDMSCIKKKAMMEPLVDTVDQNQIVTDSRLLKTMDISKMSSGDASFTAPFKLV 293
Query: 245 AKRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILE 304
A+R D+I+ L+++FD+ F +K + FSTG + THWKQTV YLED L + +
Sbjct: 294 AQRNDYIHALVAYFDVSF--TMCHKLLGFSTGPKSRATHWKQTVLYLEDVLTICEGETIT 351
Query: 305 GELTCLPNKDNNRDLDIKIVYN 326
G ++ PNK N RD+DIK+ Y+
Sbjct: 352 GTMSVSPNKKNPRDIDIKLSYS 373
>HsM9789979 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 334
Score = 321 bits (823), Expect = 9e-88
Identities = 159/307 (51%), Positives = 219/307 (70%), Gaps = 2/307 (0%)
Query: 22 HYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGA 81
+YF SY HFGIHEEML+D VRTL+YRN++ NK FK KVVLDVG GTGILSMFAAK GA
Sbjct: 15 YYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGA 74
Query: 82 KHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYE 141
K V G++ SSI + +++I++ N L + IT+ +GK+E+V LP +KVDIIISEWMGY L YE
Sbjct: 75 KKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYE 134
Query: 142 SMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFIPLV 201
SML+TV++ARD +L GGL+FPD+ ++++ +ED +YK K+++W++VYGFD + +
Sbjct: 135 SMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVA 194
Query: 202 KREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWFDIE 261
+EPLVD V+ V T C + E D+ TV +L+F S F LQ +R D+++ L+++F+IE
Sbjct: 195 MKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIE 254
Query: 262 FPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDLDI 321
F K +K + FST A YTHWKQTVFYLED L + + G ++ PN N RDLD
Sbjct: 255 F--TKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDF 312
Query: 322 KIVYNFK 328
+ +FK
Sbjct: 313 TVDLDFK 319
>Hs21314692 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 334
Score = 321 bits (823), Expect = 9e-88
Identities = 159/307 (51%), Positives = 219/307 (70%), Gaps = 2/307 (0%)
Query: 22 HYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGA 81
+YF SY HFGIHEEML+D VRTL+YRN++ NK FK KVVLDVG GTGILSMFAAK GA
Sbjct: 15 YYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGA 74
Query: 82 KHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYE 141
K V G++ SSI + +++I++ N L + IT+ +GK+E+V LP +KVDIIISEWMGY L YE
Sbjct: 75 KKVFGIECSSISDYSQKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYE 134
Query: 142 SMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFIPLV 201
SML+TV++ARD +L GGL+FPD+ ++++ +ED +YK K+++W++VYGFD + +
Sbjct: 135 SMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVA 194
Query: 202 KREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWFDIE 261
+EPLVD V+ V T C + E D+ TV +L+F S F LQ +R D+++ L+++F+IE
Sbjct: 195 MKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIE 254
Query: 262 FPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDLDI 321
F K +K + FST A YTHWKQTVFYLED L + + G ++ PN N RDLD
Sbjct: 255 F--TKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDF 312
Query: 322 KIVYNFK 328
+ +FK
Sbjct: 313 TVDLDFK 319
>At2g19670 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 366
Score = 321 bits (822), Expect = 1e-87
Identities = 162/325 (49%), Positives = 217/325 (65%), Gaps = 9/325 (2%)
Query: 2 SKTDVTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKV 61
+ DV D T +YF SY HFGIHEEML+D VRT SY++ I +NK K K+
Sbjct: 34 NNADVADDITSA-------DYYFDSYSHFGIHEEMLKDVVRTKSYQDVIYKNKFLIKDKI 86
Query: 62 VLDVGCGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVL 121
VLDVG GTGILS+F AK GA HV V+ S + + AK+IV+ NG SD IT+L+GK+E++ L
Sbjct: 87 VLDVGAGTGILSLFCAKAGAAHVYAVECSQMADTAKEIVKSNGFSDVITVLKGKIEEIEL 146
Query: 122 PYKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGE 181
P KVD+IISEWMGYFLLYE+MLDTVLYAR+ +LV+GG++ PDK S+++ +ED+ YK +
Sbjct: 147 PVPKVDVIISEWMGYFLLYENMLDTVLYARNKWLVDGGIVLPDKASLYVTAIEDAHYKDD 206
Query: 182 KLNFWQDVYGFDYSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKF 241
K+ FW DVYGFD S EPLVDTV+ + + T L D++ + D +F + F
Sbjct: 207 KVEFWDDVYGFDMSCIKRRAITEPLVDTVDGNQIVTDSKLLKTMDISKMAAGDASFTAPF 266
Query: 242 KLQAKRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEAND 301
KL A+R D I+ L+++FD+ F +K + FSTG + THWKQTV YLED L +
Sbjct: 267 KLVAQRNDHIHALVAYFDVSF--TMCHKKMGFSTGPKSRATHWKQTVLYLEDVLTICEGE 324
Query: 302 ILEGELTCLPNKDNNRDLDIKIVYN 326
+ G +T NK N RD+DIK+ Y+
Sbjct: 325 TITGSMTIAQNKKNPRDVDIKLSYS 349
>CE23297 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 348
Score = 320 bits (819), Expect = 3e-87
Identities = 170/347 (48%), Positives = 225/347 (63%), Gaps = 11/347 (3%)
Query: 5 DVTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLD 64
D +A KEL + +YF SY HFGIHEEML+D VRT +YRN+I N FK KVV+D
Sbjct: 10 DAPVAAPAAKELTS-KDYYFDSYAHFGIHEEMLKDEVRTTTYRNSIYHNSHLFKDKVVMD 68
Query: 65 VGCGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDV-VLP- 122
VG GTGILSMFAAK GAK V ++ S++ +++I+ N L + +++ K+EDV LP
Sbjct: 69 VGSGTGILSMFAAKAGAKKVFAMEFSNMALTSRKIIADNNLDHIVEVIQAKVEDVHELPG 128
Query: 123 -YKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGE 181
+KVDIIISEWMGY L YESML+TVL ARD +L G++FPDK +++ +ED +YK +
Sbjct: 129 GIEKVDIIISEWMGYCLFYESMLNTVLVARDRWLAPNGMLFPDKARLYVCAIEDRQYKED 188
Query: 182 KLNFWQDVYGFDYSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKF 241
K+++W VYGF+ S + +EPLVD V+N+ VNT C L + DL TV I DL F S F
Sbjct: 189 KIHWWDSVYGFNMSAIKNVAIKEPLVDIVDNAQVNTNNCLLKDVDLYTVKIEDLTFKSDF 248
Query: 242 KLQAKRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEAND 301
KL+ R D+I +++F +EF K +K FSTG YTHWKQTVFYL+D L + +
Sbjct: 249 KLRCTRSDYIQAFVTFFTVEF--SKCHKKTGFSTGPDVQYTHWKQTVFYLKDALTVKKGE 306
Query: 302 ILEGELTCLPNKDNNRDLDIKIVYNFKASGPDGKERSRKGTNTYLMH 348
+ G PNK+N RDLDI I ++FK D E+ NTY MH
Sbjct: 307 EITGSFEMAPNKNNERDLDINISFDFKGEVCDLNEQ-----NTYTMH 348
>Hs4504497 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 360
Score = 264 bits (674), Expect = 2e-70
Identities = 141/310 (45%), Positives = 196/310 (62%), Gaps = 5/310 (1%)
Query: 20 EQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKN 79
+ +YF SY HFGIHEEML+D VRTL+YRN++ N+ FK KVVLDVG GTGIL MFAAK
Sbjct: 40 KDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKA 99
Query: 80 GAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKV-DIIISEWMGYFL 138
GA+ VIG+ SSI + A +IV+ N L +T+++GK+E+V LP +KV S W
Sbjct: 100 GARKVIGIVCSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVASSSASGWA--TA 157
Query: 139 LYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFI 198
S T + GLIFPD+ ++++ +ED +YK K+++W++VYGFD S
Sbjct: 158 SSTSPCSTPCSMPGTSVAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIK 217
Query: 199 PLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWF 258
+ +EPLVD V+ + T C + E D+ TV + DL F S F LQ KR D+++ L+++F
Sbjct: 218 DVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYF 277
Query: 259 DIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRD 318
+IEF + +K FST + YTHWKQTVFY+ED L + + + G + PN NNRD
Sbjct: 278 NIEF--TRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRD 335
Query: 319 LDIKIVYNFK 328
LD I +FK
Sbjct: 336 LDFTIDLDFK 345
>7299975 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 516
Score = 253 bits (645), Expect = 4e-67
Identities = 129/304 (42%), Positives = 188/304 (61%), Gaps = 4/304 (1%)
Query: 20 EQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKN 79
+ YF SY HFGIH EML D VRT +YR ++ QN+ +GK VLDVGCGTGILS+FA+K
Sbjct: 205 DNEYFKSYAHFGIHHEMLSDKVRTSTYRASLLQNEAVVRGKTVLDVGCGTGILSIFASKA 264
Query: 80 GAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLL 139
GA V+G+D S I+ A I+ N + + + L++G+LED LP K DIIISEWMGYFLL
Sbjct: 265 GAARVVGIDNSDIVYTAMDIIRKNKV-ENVELIKGRLEDTDLPETKYDIIISEWMGYFLL 323
Query: 140 YESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFIP 199
YESMLD+++YAR+N+L G+I P +C++ + G D +++ FW +VY D S
Sbjct: 324 YESMLDSIIYARENHLNPNGIILPSRCTLSLLGYGDDTLYADEVEFWSNVYEVDMSDLRK 383
Query: 200 LVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWFD 259
EPL+ V+ + T ++ FD+ TV + F +F L+ + ++ + +F+
Sbjct: 384 QSIEEPLMQVVDAEFMLTEPEQIANFDIMTVDMNYPNFTHQFSLKVTKPGRLSAFVGYFE 443
Query: 260 IEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDL 319
F P PV FST AT THWKQTVF++E+ + D++ G++T +K++ R L
Sbjct: 444 TLFELP---SPVMFSTSPSATPTHWKQTVFFIENPQVVKEGDVICGKITSRRHKEDVRGL 500
Query: 320 DIKI 323
+ I
Sbjct: 501 SVDI 504
>SPBPI055 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 348
Score = 240 bits (612), Expect = 3e-63
Identities = 139/332 (41%), Positives = 187/332 (55%), Gaps = 9/332 (2%)
Query: 2 SKTDVTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKV 61
S+T S T KK N+ +YF SY IH ML D+VRT YR+ + NK F GK
Sbjct: 6 SQTTDQLSVTPKKADND--SYYFESYAGNDIHFLMLNDSVRTEGYRDFVYHNKHIFAGKT 63
Query: 62 VLDVGCGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVL 121
VLDVGCGTGILSMF AK GAK V VD S II+MA NGL+D+IT +RGK+ED+ L
Sbjct: 64 VLDVGCGTGILSMFCAKAGAKKVYAVDNSDIIQMAISNAFENGLADQITFIRGKIEDISL 123
Query: 122 PYKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGE 181
P KVDIIISEWMGY L +ESM+D+VL ARD +L G++ P + + + +++ E
Sbjct: 124 PVGKVDIIISEWMGYALTFESMIDSVLVARDRFLAPSGIMAPSETRLVLTATTNTELLEE 183
Query: 182 KLNFWQDVYGFDYSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKF 241
++FW DVYGF + + V V + VN F+++T + D++F S F
Sbjct: 184 PIDFWSDVYGFKMNGMKDASYKGVSVQVVPQTYVNAKPVVFARFNMHTCKVQDVSFTSPF 243
Query: 242 KLQAKRQDFINGLISWFDIEF------PAPKG-NKPVTFSTGAHATYTHWKQTVFYLEDD 294
L + + WFD F P P+ ++ F+TG T THWKQ V L +
Sbjct: 244 SLIIDNEGPLCAFTLWFDTYFTTKRTQPIPEAIDEACGFTTGPQGTPTHWKQCVLLLRNR 303
Query: 295 LECEANDILEGELTCLPNKDNNRDLDIKIVYN 326
+ +EG ++ NK NNRDLDI + +N
Sbjct: 304 PFLQKGTRVEGTISFSKNKKNNRDLDISVHWN 335
>SPBC8D2.10c [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 543
Score = 240 bits (612), Expect = 3e-63
Identities = 139/332 (41%), Positives = 187/332 (55%), Gaps = 9/332 (2%)
Query: 2 SKTDVTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKV 61
S+T S T KK N+ +YF SY IH ML D+VRT YR+ + NK F GK
Sbjct: 201 SQTTDQLSVTPKKADND--SYYFESYAGNDIHFLMLNDSVRTEGYRDFVYHNKHIFAGKT 258
Query: 62 VLDVGCGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVL 121
VLDVGCGTGILSMF AK GAK V VD S II+MA NGL+D+IT +RGK+ED+ L
Sbjct: 259 VLDVGCGTGILSMFCAKAGAKKVYAVDNSDIIQMAISNAFENGLADQITFIRGKIEDISL 318
Query: 122 PYKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGE 181
P KVDIIISEWMGY L +ESM+D+VL ARD +L G++ P + + + +++ E
Sbjct: 319 PVGKVDIIISEWMGYALTFESMIDSVLVARDRFLAPSGIMAPSETRLVLTATTNTELLEE 378
Query: 182 KLNFWQDVYGFDYSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKF 241
++FW DVYGF + + V V + VN F+++T + D++F S F
Sbjct: 379 PIDFWSDVYGFKMNGMKDASYKGVSVQVVPQTYVNAKPVVFARFNMHTCKVQDVSFTSPF 438
Query: 242 KLQAKRQDFINGLISWFDIEF------PAPKG-NKPVTFSTGAHATYTHWKQTVFYLEDD 294
L + + WFD F P P+ ++ F+TG T THWKQ V L +
Sbjct: 439 SLIIDNEGPLCAFTLWFDTYFTTKRTQPIPEAIDEACGFTTGPQGTPTHWKQCVLLLRNR 498
Query: 295 LECEANDILEGELTCLPNKDNNRDLDIKIVYN 326
+ +EG ++ NK NNRDLDI + +N
Sbjct: 499 PFLQKGTRVEGTISFSKNKKNNRDLDISVHWN 530
>7295728 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 355
Score = 239 bits (611), Expect = 3e-63
Identities = 132/334 (39%), Positives = 201/334 (59%), Gaps = 13/334 (3%)
Query: 7 TDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVG 66
TD+ K+ E+HYF Y IHE +L+D+VR +YR AI Q+ +FF+ K VLDVG
Sbjct: 17 TDANQIIKDRRRQEEHYFKLYGRIEIHEWLLKDSVRIKAYREAI-QHNEFFRHKTVLDVG 75
Query: 67 CGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLP--YK 124
CG G+LSMFAAK G+K V+ V+ ++I E A+Q+V+ N I +++GK+ED+ LP K
Sbjct: 76 CGMGVLSMFAAKAGSKRVLAVEAATISEFAQQVVQDNEFGRVIQVIQGKVEDIELPDGIK 135
Query: 125 KVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLN 184
KVDII+ +WMG L +ML+++L+ARD +L G I+PD +++A + K + + L
Sbjct: 136 KVDIIVCDWMGSCLFSGNMLESLLFARDKWLSATGHIYPDTAQLYLAAI---KGRDQDLG 192
Query: 185 FWQDVYGFDYSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQ 244
FW DV+GFD S + + +V+ V + + C + DL T S F+L+
Sbjct: 193 FWHDVHGFDLSAIRRRCESKAVVEHVTGDQMMSRVCLVKSLDLYTEPRQSAKSRSLFELK 252
Query: 245 AKRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILE 304
R +++GL+++FD+ F K + ++FST A +THW QTVFYLE L A + ++
Sbjct: 253 VSRNGWVHGLVAYFDVGF--SKSTQRISFSTSPSAPWTHWNQTVFYLETPLPVRAGECIK 310
Query: 305 GELTCLPNKDNNRDLDIKIVYNFKASGPDGKERS 338
G LT P++D+ D + I NF DG+E+S
Sbjct: 311 GVLTMKPSEDSIFDTEFDIFVNF-----DGREKS 339
>7299824 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 341
Score = 220 bits (560), Expect = 3e-57
Identities = 117/311 (37%), Positives = 183/311 (58%), Gaps = 3/311 (0%)
Query: 20 EQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKN 79
+ YF SY H ML+D+VR ++R+AI Q+ F+ K+VLDVGCGTGILS+FAA+
Sbjct: 16 DSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKIVLDVGCGTGILSLFAAEA 75
Query: 80 GAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLP--YKKVDIIISEWMGYF 137
GA VI V+ + I ++A++I+ N + + +++G +E V LP +KVDII+SEWMG
Sbjct: 76 GASKVIAVECTDIADIAEEIIRDNQKENVVKVVKGLVEQVELPDGIEKVDIIVSEWMGNA 135
Query: 138 LLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPF 197
L E+M+++VL+ARD +L GG I P ++ + G D ++ LNFW +V G D
Sbjct: 136 LYMEAMINSVLFARDKWLTRGGRILPSTGNLWLMGAYD-PHRRTNLNFWCNVEGIDMGCV 194
Query: 198 IPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISW 257
+EPLV+ V + T +C + +L + F S F+L+ R IN L+ +
Sbjct: 195 RKPFSQEPLVEFVPIQQLLTDECFIHSTNLAVARNQPVEFQSNFQLKVMRTGIINMLVLY 254
Query: 258 FDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNR 317
FD+ FP+ K NK V+ +T H+ +THW+QTV +L++ L D + G L P + R
Sbjct: 255 FDVLFPSGKSNKSVSLTTSPHSPWTHWEQTVLHLDEPLYVRIRDRVRGVLAMTPTGQDGR 314
Query: 318 DLDIKIVYNFK 328
++ + +F+
Sbjct: 315 GMNFDLHISFR 325
>At3g20020 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 409
Score = 217 bits (552), Expect = 2e-56
Identities = 111/253 (43%), Positives = 164/253 (63%), Gaps = 6/253 (2%)
Query: 18 EYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAA 77
+++ YF SY H GIHEEM++D RT +YR AI Q++ +GKVV+DVGCGTGILS+F A
Sbjct: 78 DFDVAYFHSYAHVGIHEEMIKDRARTETYREAIMQHQSLIEGKVVVDVGCGTGILSIFCA 137
Query: 78 KNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYF 137
+ GAK V VD S I AK++V+ NGLSDK+ +L G++EDV + ++VD+IISEWMGY
Sbjct: 138 QAGAKRVYAVDASDIAVQAKEVVKANGLSDKVIVLHGRVEDVEID-EEVDVIISEWMGYM 196
Query: 138 LLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPF 197
LLYESML +V+ ARD +L GGLI P ++++A + ++FW++VYG D S
Sbjct: 197 LLYESMLGSVITARDRWLKPGGLILPSHATLYMAPISHPDRYSHSIDFWRNVYGIDMSAM 256
Query: 198 IPLVKR----EPLVDTVENSSVNTTKCKLIEFDLNTVTIPDL-AFHSKFKLQAKRQDFIN 252
+ L K+ EP V+++ +V T + D T+ I +L + +++K + + ++
Sbjct: 257 MQLAKQCAFEEPSVESISGENVLTWPEVVKHIDCKTIKIQELDSVTARYKFNSMMRAPMH 316
Query: 253 GLISWFDIEFPAP 265
G WFD+EF P
Sbjct: 317 GFAFWFDVEFSGP 329
>Hs4504495 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 433
Score = 196 bits (497), Expect = 6e-50
Identities = 110/325 (33%), Positives = 175/325 (53%), Gaps = 16/325 (4%)
Query: 14 KELNEYE-------QHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVG 66
K ++EY+ + YF SY +H EML D RT Y + I QNK+ KV+LDVG
Sbjct: 86 KHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVG 145
Query: 67 CGTGILSMFAAKNGA-KHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKK 125
CGTGI+S+F A + V V+ S + + Q+V NG +D IT+ + K+EDVVLP +K
Sbjct: 146 CGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EK 204
Query: 126 VDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNF 185
VD+++SEWMG LL+E M++++LYARD +L E G+I+P ++H+ + K+ F
Sbjct: 205 VDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADRIIVAKVLF 264
Query: 186 WQDVYGFDYSPFIPLVKREPLVDTVENSSVN-----TTKCKLIEFDLNTVTIPDL-AFHS 239
W + Y F+ S L +E N + + C +++ D+ TV I DL
Sbjct: 265 WDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRG 324
Query: 240 KFKLQAKRQDFINGLISWFDIEFPA-PKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECE 298
+ + ++ ++G +WF + F + +G P STG THWKQT+F ++D +
Sbjct: 325 ELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVH 384
Query: 299 ANDILEGELTCLPNKDNNRDLDIKI 323
D++ G + N R + + +
Sbjct: 385 TGDVVTGSVVLQRNPVWRRHMSVAL 409
>At3g12270 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 590
Score = 194 bits (494), Expect = 1e-49
Identities = 113/314 (35%), Positives = 165/314 (51%), Gaps = 18/314 (5%)
Query: 6 VTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDV 65
V D + + + ++YF SY FGIH EML D VRT +YR+A+ +N G VV+DV
Sbjct: 224 VCDGRLVNRNIRKVNENYFGSYSSFGIHREMLSDKVRTEAYRDALLKNPTLLNGSVVMDV 283
Query: 66 GCGTGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLED----VVL 121
GCGTGILS+FAAK GA V+ V+ S + ++ N + + + +E+ + +
Sbjct: 284 GCGTGILSLFAAKAGASRVVAVEASEKMAKDNKVFNDNEHNGVLEVAHSMVEELDKSIQI 343
Query: 122 PYKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGE 181
VD+++SEWMGY LLYESML +VLYARD +L GG I PD ++ +AG
Sbjct: 344 QPHSVDVLVSEWMGYCLLYESMLSSVLYARDRWLKPGGAILPDTATMFVAGFGKG---AT 400
Query: 182 KLNFWQDVYGFDYSPFIPLV----KREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAF 237
L FW+DVYGFD S + R P+VD + + T L FDL T+ ++ F
Sbjct: 401 SLPFWEDVYGFDMSSIGKEIHDDTTRLPIVDVIAERDLVTQPTLLQTFDLATMKPDEVDF 460
Query: 238 HSKFKLQAKRQD----FINGLISWFDIEFPAP--KGNKPVTFSTGAHATYTHWKQTVFYL 291
+ L+ + +G++ WFD F + K N P ST + THW QT+
Sbjct: 461 TATATLEPTESEAKTRLCHGVVLWFDTGFTSRFCKEN-PTVLSTSPYTPPTHWAQTILTF 519
Query: 292 EDDLECEANDILEG 305
++ + +L G
Sbjct: 520 QEPISVAPASVLSG 533
>Hs8922515 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 316
Score = 191 bits (485), Expect = 1e-48
Identities = 111/302 (36%), Positives = 166/302 (54%), Gaps = 14/302 (4%)
Query: 36 MLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGAKHVIGVDMSSIIEM 95
M+ D VRT +YR I +N +GK VLDVG GTGILS+F A+ GA+ V V+ S+I +
Sbjct: 1 MIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQ 60
Query: 96 AKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYESMLDTVLYARDNYL 155
A+++V NGL D++ +L G +E V LP ++VD I+SEWMGY LL+ESML +VL+AR +L
Sbjct: 61 AREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWMGYGLLHESMLSSVLHARTKWL 119
Query: 156 VEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDV---YGFDYSPFIPLVKR------EPL 206
EGGL+ P + IA + D + +L FW V YG D S R E +
Sbjct: 120 KEGGLLLPASAELFIAPISDQMLEW-RLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIV 178
Query: 207 VDTVENSSVNTTKCKLIEFDLNTVTIP---DLAFHSKFKLQAKRQDFINGLISWFDIEFP 263
V + V + + +L+ + + +F+ ++G WF + FP
Sbjct: 179 VQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFP 238
Query: 264 APKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDLDIKI 323
+ KP+ ST THWKQ + YL + ++ E + + GE+T LP++DN R L + +
Sbjct: 239 GGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLL 298
Query: 324 VY 325
Y
Sbjct: 299 RY 300
>Hs18601084 [OK] KOG1500 Protein arginine N-methyltransferase CARM1
Length = 608
Score = 172 bits (436), Expect = 7e-43
Identities = 115/321 (35%), Positives = 168/321 (51%), Gaps = 21/321 (6%)
Query: 23 YFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGAK 82
YF Y + + M+QD VRT +Y+ AI QN FK K+VLDVGCG+GILS FAA+ GA+
Sbjct: 149 YFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGAR 208
Query: 83 HVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYES 142
+ V+ S++ + A+ +V+ N L+D+I ++ GK+E+V LP ++VDIIISE MGY L E
Sbjct: 209 KIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNER 267
Query: 143 MLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGE---KLNFW--QDVYGFDYSPF 197
ML++ L+A+ YL G +FP +H+A D + E K NFW +G D S
Sbjct: 268 MLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSAL 326
Query: 198 ----IPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHS---KFKLQAKRQDF 250
+ R+P+VDT + + K +++ +N + + H FK
Sbjct: 327 RGAAVDEYFRQPVVDTFD---IRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGL 383
Query: 251 INGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCL 310
++GL WFD+ F V ST THW Q + L +A D L G TCL
Sbjct: 384 VHGLAFWFDVAFIG--SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSG--TCL 439
Query: 311 PNKDNNRDLDIKIVYNFKASG 331
+ + DI IV +G
Sbjct: 440 LIANKRQSYDISIVAQVDQTG 460
>Hs14780868 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 375
Score = 171 bits (432), Expect = 2e-42
Identities = 98/284 (34%), Positives = 154/284 (53%), Gaps = 15/284 (5%)
Query: 14 KELNEYE-------QHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVG 66
K ++EY+ + YF SY +H EML D RT Y + I QNK+ KV+LDVG
Sbjct: 86 KHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVG 145
Query: 67 CGTGILSMFAAKNGA-KHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKK 125
CGTGI+S+F A + V V+ S + + Q+V NG +D IT+ + K+EDVVLP +K
Sbjct: 146 CGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EK 204
Query: 126 VDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNF 185
VD+++SEWMG LL+E M++++LYARD +L E G+I+P ++H+ K K+ F
Sbjct: 205 VDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLF 264
Query: 186 WQDVYGFDYSPFIPLVKREPLVDTVENSSVN-----TTKCKLIEFDLNTVTIPDL-AFHS 239
W + Y F+ S L +E N + + C +++ D+ TV I DL
Sbjct: 265 WDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRG 324
Query: 240 KFKLQAKRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTH 283
+ + ++ ++G +WF + F + + +P S +T H
Sbjct: 325 ELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQCSAPGPSTPPH 368
>7297802 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 324
Score = 159 bits (403), Expect = 4e-39
Identities = 100/271 (36%), Positives = 151/271 (54%), Gaps = 17/271 (6%)
Query: 36 MLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGAKHVIGVDMSSII-E 94
ML+D R +Y NAI NKD FK K+V+DVG GTGILS F AK GA+ V V+ S++ +
Sbjct: 1 MLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLVYAVEASNVATK 60
Query: 95 MAKQIVELNGLSDKITLLRGKLEDVVLPYK--KVDIIISEWMGYFLLYESMLDTVLYARD 152
+A ++E NGL++ + +++ ++E+ VLP + KVDII+SEWMG++LL+E MLD+VL ARD
Sbjct: 61 VALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLLARD 120
Query: 153 NYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFIPLVKRE----PLVD 208
+L EGGL+FP +C+I +A + W +V G F ++ + P +
Sbjct: 121 KFLKEGGLLFPSECTIFVAPCSVPSL----FDDWHNVDGIKMDTFARKLRTQKSSRPEIT 176
Query: 209 TVENSSVNTTKCKLIEFDLNTVTIPDL-AFHSKFKLQAKRQDFINGLISWFDIEFPAPKG 267
+ + +L V DL + K + A++ G WFD++FP
Sbjct: 177 QLNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAGNHQGFCIWFDVQFP---- 232
Query: 268 NKPVTFSTGAHATYTHWKQTVFYLEDDLECE 298
+ ST + THWKQ V L ++ CE
Sbjct: 233 GEDFVLSTSPLSPPTHWKQCVVVLPEE-SCE 262
>7299276 [OK] KOG1500 Protein arginine N-methyltransferase CARM1
Length = 530
Score = 158 bits (400), Expect = 1e-38
Identities = 113/329 (34%), Positives = 168/329 (50%), Gaps = 28/329 (8%)
Query: 11 TQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTG 70
+Q+ E + Q YF Y + + M+QD VRT +Y+ AI N F+ K+VLDVG G+G
Sbjct: 133 SQRTEESSASQ-YFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSG 191
Query: 71 ILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIII 130
ILS FA + GA V ++ S++ + A+Q+VE N + KI+++ GK+E++ LP +KVD+II
Sbjct: 192 ILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELP-EKVDVII 250
Query: 131 SEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGE---KLNFWQ 187
SE MGY L E ML+T L+AR +L G ++P +HIA D E K NFW
Sbjct: 251 SEPMGYMLYNERMLETYLHAR-KWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWY 309
Query: 188 D--VYGFDYSPF----IPLVKREPLVDTVENSSVNTTKCKLI-------EFDLNTVTIPD 234
+G D + + R+P+VDT + + + E DL+ ++IP
Sbjct: 310 QSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISIP- 368
Query: 235 LAFHSKFKLQAKRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDD 294
L FH + +GL WFD+EF N V ST A THW Q L
Sbjct: 369 LEFH------ILQTGICHGLAFWFDVEFSGSSQN--VWLSTSPTAPLTHWYQVRCLLPMP 420
Query: 295 LECEANDILEGELTCLPNKDNNRDLDIKI 323
+ + L G + N+ + D+ I +
Sbjct: 421 IFIKQGQTLTGRVLLEANRRQSYDVTIDL 449
>At1g04870 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 383
Score = 156 bits (395), Expect = 4e-38
Identities = 112/369 (30%), Positives = 187/369 (50%), Gaps = 50/369 (13%)
Query: 9 SATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCG 68
SA KE+ +Y Q YF +Y ++ML D VR +Y NA+ QNK F+GK VLDVG G
Sbjct: 23 SAPVDKEV-DYAQ-YFCTYSFLYHQKDMLSDRVRMDAYFNAVFQNKHHFEGKTVLDVGTG 80
Query: 69 TGILSMFAAKNGAKHVIGVDMSSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDI 128
+GIL++++A+ GA+ V V+ + + + A+ +V+ N L + ++ G +ED+ LP +KVD+
Sbjct: 81 SGILAIWSAQAGARKVYAVEATKMADHARALVKANNLDHIVEVIEGSVEDISLP-EKVDV 139
Query: 129 IISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNF--- 185
IISEWMGYFLL ESM D+V+ ARD +L G+++P + +A ++ + ++ +F
Sbjct: 140 IISEWMGYFLLRESMFDSVISARDRWLKPTGVMYPSHARMWLAPIKSNIADRKRNDFDGA 199
Query: 186 ---WQDV-------YGFDYSPFIPLVKREPLVDTVENSSVNT-------------TKCKL 222
W + YG D V +P + E + T T +
Sbjct: 200 MADWHNFSDEIKSYYGVDMG-----VLTKPFAEEQEKYYIQTAMWNDLNPQQIIGTPTIV 254
Query: 223 IEFDLNTVTIPDLAFHSKFKLQAKRQDFIN-------GLISWFDIEFPAPK---GNKPVT 272
E D T ++ ++ ++++ IN G WFD++F K + +
Sbjct: 255 KEMDCLTASVSEIE-----EVRSNVTSVINMEHTRLCGFGGWFDVQFSGRKEDPAQQEIE 309
Query: 273 FSTGAHATY-THWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDLDIKIVYNFKASG 331
+T + THW Q VF + + + E D L L +K+N+R ++I++ K +
Sbjct: 310 LTTAPSEQHCTHWGQQVFIMSNPINVEEGDNLNLGLLMSRSKENHRLMEIELNCEIKEAS 369
Query: 332 PDGKERSRK 340
+ KE +K
Sbjct: 370 GNPKESFKK 378
>At3g06930 [OK] KOG1500 Protein arginine N-methyltransferase CARM1
Length = 388
Score = 154 bits (389), Expect = 2e-37
Identities = 112/331 (33%), Positives = 169/331 (50%), Gaps = 29/331 (8%)
Query: 23 YFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGAK 82
YF Y + MLQD VRT +Y A+ +N F G+VV+DVG G+GILSMFAA+ GAK
Sbjct: 2 YFHYYGQLLHQQNMLQDYVRTGTYYAAVMENHSDFAGRVVVDVGAGSGILSMFAAQAGAK 61
Query: 83 HVIGVDMSSIIEMAKQIVELNGL-SDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYE 141
HV V+ S + E A++++ N L +D+IT+++GK+ED+ LP +K DI+ISE MG L+ E
Sbjct: 62 HVYAVEASEMAEYARKLIAGNPLFADRITVIKGKVEDIELP-EKADILISEPMGTLLVNE 120
Query: 142 SMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLN---FW--QDVYGFDYSP 196
ML++ + ARD ++ G +FP IH+A D E N FW Q+ YG D +P
Sbjct: 121 RMLESYVIARDRFMTPKGKMFPTVGRIHMAPFSDEFLFIEMANKAMFWQQQNYYGVDLTP 180
Query: 197 FIPLVKR----EPLVDTVE-NSSVNTTKCKLIEF------DLNTVTIPDLAFHSKFKLQA 245
+ +P+VD + V + +I+F D + IP K A
Sbjct: 181 LYGSAHQGYFSQPVVDAFDPRLLVASPMFHMIDFTQMKEEDFYEIDIP-------LKFTA 233
Query: 246 KRQDFINGLISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEG 305
++GL WFD+ F + +T + GA THW Q L + A + G
Sbjct: 234 SMCTRMHGLACWFDVLFDGSTVQRWLTTAPGAPT--THWYQIRCVLSQPIYVMAGQEITG 291
Query: 306 ELTCLPNKDNNRDLDIKIVYNFKASGPDGKE 336
L + + + +D+ + + K GP +
Sbjct: 292 RLHLIAHSAQSYTIDLTL--SAKMWGPGASQ 320
>Hs22061930 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 201
Score = 149 bits (376), Expect = 6e-36
Identities = 76/193 (39%), Positives = 112/193 (57%), Gaps = 1/193 (0%)
Query: 134 MGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFD 193
MGYFLL+ESMLD+VLYA++ YL +GG ++PD C+I + + D +++ FW DVYGF
Sbjct: 1 MGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFK 60
Query: 194 YSPFIPLVKREPLVDTVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFING 253
S V E +V+ ++ ++ + C + D +T +I DL F S F L+ R
Sbjct: 61 MSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTA 120
Query: 254 LISWFDIEFPAPKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNK 313
+ +FDI F N+ V FSTG +T THWKQTVF LE +A + L+G++T NK
Sbjct: 121 IAGYFDIYFEKNCHNR-VVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNK 179
Query: 314 DNNRDLDIKIVYN 326
+ R L + + N
Sbjct: 180 KDPRSLTVTLTLN 192
>At5g49020 [OK] KOG1500 Protein arginine N-methyltransferase CARM1
Length = 577
Score = 144 bits (363), Expect = 2e-34
Identities = 114/373 (30%), Positives = 172/373 (45%), Gaps = 64/373 (17%)
Query: 23 YFTSYDHFGIHEEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGAK 82
YF Y + MLQD VRT +Y A+ +N+ F G+VV+DVG G+GILSMFAA GAK
Sbjct: 151 YFHYYGQLLHQQNMLQDYVRTGTYHAAVMENRSDFSGRVVVDVGAGSGILSMFAALAGAK 210
Query: 83 HVIGVDMSSIIEMAKQIVELNG-LSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYE 141
HV V+ S + E A++++ N L+++IT+++GK+ED+ LP +K D++ISE MG L+ E
Sbjct: 211 HVYAVEASEMAEYARKLIAGNPLLAERITVIKGKIEDIELP-EKADVLISEPMGTLLVNE 269
Query: 142 SMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLN---FW--QDVYGFDYSP 196
ML+T + ARD +L G +FP IH+A D E N FW Q+ YG D +P
Sbjct: 270 RMLETYVIARDRFLSPNGKMFPTVGRIHMAPFADEFLFVEMANKALFWQQQNYYGVDLTP 329
Query: 197 FIPLVKR----EPLVDTVE-NSSVNTTKCKLIEF-------------------------- 225
+ +P+VD + V + +I+F
Sbjct: 330 LYVSAHQGYFSQPVVDAFDPRLLVAPSMFHVIDFTMMTVKLFPTLDSVPRCFLKIEDTFL 389
Query: 226 ---------------DLNTVTIPDLAFHSKF-------KLQAKRQDFINGLISWFDIEFP 263
D N++T+ + +F K A I+GL WFD+ F
Sbjct: 390 SCYFYVQSSLFSEWHDPNSITVKFFSQEEQFYEIDIPLKFTASVCTRIHGLACWFDVLFD 449
Query: 264 APKGNKPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDLDIKI 323
+ F+T A THW Q L + A + G L + + + + I +
Sbjct: 450 GSTVQR--WFTTAPGAPTTHWYQIRCVLSQPIHVMAGQEITGRLHLIAH--SAQSYTINL 505
Query: 324 VYNFKASGPDGKE 336
+ K GP +
Sbjct: 506 TLSAKMWGPGANQ 518
>7299823 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 313
Score = 142 bits (357), Expect = 9e-34
Identities = 88/292 (30%), Positives = 149/292 (50%), Gaps = 9/292 (3%)
Query: 34 EEMLQDTVRTLSYRNAIAQNKDFFKGKVVLDVGCGTGILSMFAAKNGAKHVIGVDMSSII 93
+ ML D + T +Y + + FK K+VLDVGC +G+LS+ + + GA V+ +
Sbjct: 13 DSMLNDVISTRAYEWVFKRYERLFKDKIVLDVGCRSGLLSLMSVEAGAVKVMALGNRESA 72
Query: 94 EMAKQIVELNGLSDKITLLRGKLEDVVLP--YKKVDIIISEWMGYFLLYESMLDTVLYAR 151
E + D + G + ++VLP KKVDII+SEW+G+ + +S+ V++AR
Sbjct: 73 EFVSKAFIGTEKEDIFEFIDGDIHEIVLPCGLKKVDIIVSEWVGHSVFVDSLFKEVIFAR 132
Query: 152 DNYLVEGGLIFPDKCSIHIAGLEDSKYKGEKLNFWQDVYGFDYSPFIPLVKREP---LVD 208
+ +LV+GG I P+ + + G+ D K ++N DY P + REP + D
Sbjct: 133 EKWLVKGGFIIPNVAQLFVCGIADHPRKTVEVNILPQ---SDY-PGRSYMVREPVSLIED 188
Query: 209 TVENSSVNTTKCKLIEFDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWFDIEFPAPKGN 268
V + T K L DL T I D +F FKL+ R + ++ + DI P+G
Sbjct: 189 YVAKEQLITEKYLLKTIDLCTAHINDESFRVPFKLRGLRDSQLGAVVLYSDIGLCRPRGK 248
Query: 269 KPVTFSTGAHATYTHWKQTVFYLEDDLECEANDILEGELTCLPNKDNNRDLD 320
+ FSTG T+ +QT+ ++++ +E +++ GEL D +R+++
Sbjct: 249 FRLMFSTGPKRPRTYVRQTILFMDNPVEVAKCELVIGELGMYYKPDEHREVE 300
>Hs18571812 [OK] KOG1500 Protein arginine N-methyltransferase CARM1
Length = 90
Score = 68.6 bits (166), Expect = 1e-11
Identities = 41/91 (45%), Positives = 57/91 (62%), Gaps = 5/91 (5%)
Query: 99 IVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEG 158
+V+ N LSDKI +L GK EDV LP + VD+IISE MGY L E ML++ L+++ +L
Sbjct: 2 LVKNNHLSDKIIVLPGKTEDVSLP-EAVDVIISEPMGYMLFNERMLESYLHSK-KWLKSN 59
Query: 159 GLIFPDKCSIHIAGLEDSKYKGE---KLNFW 186
G++FP IH+A D + E + NFW
Sbjct: 60 GMMFPTFSDIHLAPFSDEQLYVEHFSRANFW 90
>Hs9506615 [R] KOG1501 Arginine N-methyltransferase
Length = 692
Score = 67.0 bits (162), Expect = 4e-11
Identities = 80/351 (22%), Positives = 149/351 (41%), Gaps = 49/351 (13%)
Query: 28 DHFGIHEE--------MLQDTVRTLSY----RNAIAQNKDFFKGKVVLDVGCGTGILSMF 75
+H+ H+E ML D R + Y R A+++ KD + +VLD+G GTG+LSM
Sbjct: 22 EHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMM 81
Query: 76 AAKNGAKHVIGVDM-SSIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYK-----KVDII 129
A GA +++ + + A +IVE NG SDKI ++ +V + + + +I+
Sbjct: 82 AVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANIL 141
Query: 130 ISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSK-YKGEKLNFWQD 188
++E L+ E L + +A + + E P + +++ +E + + KL
Sbjct: 142 VTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHV 201
Query: 189 VYGFDYSPFIPLVKRE-----PLVDTVENSSVN-------TTKCKLIEFDLNTVTIPDLA 236
+P V E P V ++ + V+ + + D + A
Sbjct: 202 QTSLGEQVIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAA 261
Query: 237 FHSKFKLQAKRQDFINGLISWFDIEFPAPKGNKPVTFST-GAHAT------YTHWKQTVF 289
HS+ + + ++SW+DIE P+G T + AH+ HW Q V+
Sbjct: 262 CHSR-RFEPLTSGRAQVVLSWWDIEMD-PEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVY 319
Query: 290 YLEDDLECEANDILEGELTCLPNKDNNRDLDIKIVYNFKASGPDGKERSRK 340
+L + +++G L + D + Y+ + + P+ ER R+
Sbjct: 320 FLPQE-----EPVVQGSALYLVAHHD----DYCVWYSLQRTSPEKNERVRQ 361
>7291527 [R] KOG1501 Arginine N-methyltransferase
Length = 406
Score = 58.9 bits (141), Expect = 1e-08
Identities = 72/332 (21%), Positives = 130/332 (38%), Gaps = 46/332 (13%)
Query: 6 VTDSATQKKELNEYEQHYFTSYDHFGIHEEMLQDTVRTLSY----RNAIAQNKDFFKGKV 61
+T + ++ ++Y+ H + FG +ML D R Y R IA ++ +
Sbjct: 11 ITGQNSWQERGDDYDYHLEVANAGFG---DMLHDWERNQKYFAALRKTIAGMREAGREVH 67
Query: 62 VLDVGCGTGILSMFAAKNGAKHVIGVD-MSSIIEMAKQIVELNGLSDKITLLRGKLEDVV 120
VLD+G GTGILSM A GA V + + A++I+ NG DK+ L+R + ++
Sbjct: 68 VLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGAGDKVRLIRKRSTEIQ 127
Query: 121 LPY---KKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIFPDKCSIHIAGLEDSK 177
+ +K +++++E + L+ E + +A L E L P + + A + S
Sbjct: 128 VGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCY-AQVAQSP 186
Query: 178 YKGEKLNFWQDVYGFDYSPF------IPLVKREPLVDTVENSSVN-------TTKCKLIE 224
+ N + + D P + + E + V+ S + T ++ +
Sbjct: 187 LAAQ-WNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQ 245
Query: 225 FDLNTVTIPDLAFHSKFKLQAKRQDFINGLISWFDIEFP---------APKGNKPVTFST 275
FD + KLQ+K+ + W+DI+ AP P
Sbjct: 246 FDFQRKQEREKQRSQLLKLQSKQPGAAELVFYWWDIQLDDDGEILLSCAPYWAHPQLKEL 305
Query: 276 GAHAT-----------YTHWKQTVFYLEDDLE 296
A HW Q ++Y+ L+
Sbjct: 306 AAEKAKDHPLPNVVPWRDHWMQAIYYIPKPLQ 337
>CE16546 [R] KOG1501 Arginine N-methyltransferase
Length = 630
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/137 (31%), Positives = 71/137 (51%), Gaps = 4/137 (2%)
Query: 47 RNAIAQNK-DFFKGKV-VLDVGCGTGILSMFAAKNGAKHVIGVDM-SSIIEMAKQIVELN 103
+ IA+ K + GKV VLD+G GTG+LS+ AA+ GA V +++ + + A+ I +
Sbjct: 51 KTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNS 110
Query: 104 GLSDKITLLRGKLEDV-VLPYKKVDIIISEWMGYFLLYESMLDTVLYARDNYLVEGGLIF 162
SDKIT++ + DV + + DII++E L+ E L T A + G +
Sbjct: 111 PWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVV 170
Query: 163 PDKCSIHIAGLEDSKYK 179
P +++I +E K
Sbjct: 171 PSTGNVYIVPVESHLLK 187
>CE18281 [OKT] KOG1499 Protein arginine N-methyltransferase PRMT1 and
related enzymes
Length = 680
Score = 49.7 bits (117), Expect = 6e-06
Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 6/140 (4%)
Query: 33 HEEMLQDTVRTLSYRNAIAQNKDFFKGK--VVLDVGCGTGILSMFAAKNGAKHVIGVDMS 90
H M+ D R ++ A+ D K + VV D+G GTGILS AA+ +
Sbjct: 142 HIRMINDVKRNEAFAKAL---NDTIKSRITVVFDIGSGTGILSAIAARKTNLVTALEENM 198
Query: 91 SIIEMAKQIVELNGLSDKITLLRGKLEDVVLPYKKVDIIISEWMGYFLLYESMLDTVLYA 150
+ ++K++++ NG+ ++ + K +K DI++SE + + E +++T L A
Sbjct: 199 CLTMISKEVLKRNGVESRVN-VHAKNSTYFETCEKADIVVSETLDCCVFGEKIVETFLDA 257
Query: 151 RDNYLVEGGLIFPDKCSIHI 170
+ + + P + ++++
Sbjct: 258 HVRFSHDRTIFIPHQATVYV 277
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,043,289
Number of Sequences: 60738
Number of extensions: 993939
Number of successful extensions: 2391
Number of sequences better than 1.0e-05: 32
Number of HSP's better than 0.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2299
Number of HSP's gapped (non-prelim): 34
length of query: 348
length of database: 30,389,216
effective HSP length: 107
effective length of query: 241
effective length of database: 23,890,250
effective search space: 5757550250
effective search space used: 5757550250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)