ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1759 check: MH T KOG0616 Signal transduction mechanisms cAMP-dependent protein kinase catalytic subunit (PKA)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1759 625973 624609 -455
(455 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 583 e-166
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 569 e-162
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 509 e-144
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 392 e-109
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 319 6e-87
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 318 1e-86
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 315 9e-86
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 312 8e-85
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 303 5e-82
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 298 1e-80
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 295 1e-79
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 290 2e-78
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 269 7e-72
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 269 7e-72
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 254 2e-67
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 253 4e-67
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 249 6e-66
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 247 2e-65
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 247 3e-65
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 246 4e-65
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 245 9e-65
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 245 1e-64
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 244 3e-64
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 243 3e-64
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 242 7e-64
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 241 1e-63
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 241 2e-63
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 241 2e-63
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 239 5e-63
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 237 2e-62
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 237 2e-62
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 237 3e-62
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 236 5e-62
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 235 9e-62
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 234 2e-61
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 234 2e-61
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 234 2e-61
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 233 3e-61
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 233 6e-61
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 232 8e-61
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 231 1e-60
CE29092 [T] KOG0694 Serine/threonine protein kinase 231 1e-60
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 231 2e-60
CE15612 [T] KOG0690 Serine/threonine protein kinase 230 4e-60
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 230 4e-60
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 229 5e-60
7300106 [T] KOG0690 Serine/threonine protein kinase 229 5e-60
7302860 [T] KOG0696 Serine/threonine protein kinase 228 1e-59
7301734 [T] KOG0694 Serine/threonine protein kinase 228 2e-59
7295638 [T] KOG0603 Ribosomal protein S6 kinase 227 2e-59
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 226 5e-59
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 226 7e-59
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 226 7e-59
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 224 3e-58
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 223 4e-58
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 223 5e-58
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 223 6e-58
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 223 6e-58
CE05274 [T] KOG0690 Serine/threonine protein kinase 221 1e-57
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 221 2e-57
CE02586 [T] KOG0696 Serine/threonine protein kinase 221 2e-57
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 220 3e-57
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 219 7e-57
CE17354 [T] KOG0694 Serine/threonine protein kinase 219 7e-57
CE17353 [T] KOG0694 Serine/threonine protein kinase 219 7e-57
7296166 [T] KOG0614 cGMP-dependent protein kinase 219 7e-57
CE29298 [T] KOG0690 Serine/threonine protein kinase 218 1e-56
CE18646 [T] KOG0690 Serine/threonine protein kinase 218 1e-56
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 216 4e-56
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 216 6e-56
7303111 [T] KOG0695 Serine/threonine protein kinase 215 1e-55
7302861 [T] KOG0696 Serine/threonine protein kinase 214 2e-55
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 213 4e-55
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 213 4e-55
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 213 4e-55
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 212 8e-55
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 212 1e-54
7303915 [T] KOG0694 Serine/threonine protein kinase 211 1e-54
7303914 [T] KOG0694 Serine/threonine protein kinase 211 1e-54
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 211 2e-54
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 210 3e-54
7294770 [T] KOG0603 Ribosomal protein S6 kinase 210 3e-54
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 210 4e-54
CE03979 [T] KOG0614 cGMP-dependent protein kinase 210 4e-54
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 209 9e-54
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 207 3e-53
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 207 3e-53
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 206 4e-53
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 206 8e-53
7297611 [T] KOG0614 cGMP-dependent protein kinase 204 2e-52
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 203 5e-52
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 203 5e-52
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 203 5e-52
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 202 8e-52
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 202 8e-52
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 201 1e-51
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 201 2e-51
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 201 2e-51
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 200 4e-51
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 199 5e-51
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 199 5e-51
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 199 7e-51
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 199 9e-51
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 199 9e-51
CE19898 [T] KOG0614 cGMP-dependent protein kinase 199 9e-51
CE19897 [T] KOG0614 cGMP-dependent protein kinase 199 9e-51
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 198 1e-50
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 197 3e-50
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 197 3e-50
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 196 5e-50
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 196 6e-50
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 196 8e-50
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 196 8e-50
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 194 2e-49
CE02604 [T] KOG0695 Serine/threonine protein kinase 194 2e-49
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 194 2e-49
YBL105c [T] KOG0694 Serine/threonine protein kinase 193 4e-49
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 191 1e-48
CE18699 [T] KOG0694 Serine/threonine protein kinase 191 1e-48
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 190 4e-48
7293735 [R] KOG0605 NDR and related serine/threonine kinases 190 4e-48
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 189 6e-48
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 189 7e-48
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 188 2e-47
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 188 2e-47
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 187 2e-47
At2g45490 [D] KOG0580 Serine/threonine protein kinase 186 6e-47
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 186 8e-47
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 186 8e-47
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 183 4e-46
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 182 7e-46
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 181 2e-45
CE02074 [T] KOG0986 G protein-coupled receptor kinase 179 6e-45
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 179 8e-45
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 179 8e-45
CE24761 [D] KOG0580 Serine/threonine protein kinase 178 1e-44
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 177 3e-44
YPL209c [D] KOG0580 Serine/threonine protein kinase 176 5e-44
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 175 1e-43
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 175 1e-43
7299536 [D] KOG0580 Serine/threonine protein kinase 175 1e-43
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 175 1e-43
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 174 2e-43
At4g32830 [D] KOG0580 Serine/threonine protein kinase 174 2e-43
At3g14370 [R] KOG0610 Putative serine/threonine protein kinase 174 3e-43
At2g25090 [T] KOG0583 Serine/threonine protein kinase 173 5e-43
At2g25880 [D] KOG0580 Serine/threonine protein kinase 172 7e-43
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 172 9e-43
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 172 1e-42
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 172 1e-42
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 171 2e-42
At1g30270 [T] KOG0583 Serine/threonine protein kinase 171 3e-42
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 171 3e-42
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 170 4e-42
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 169 6e-42
CE21025 [D] KOG0580 Serine/threonine protein kinase 169 8e-42
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 168 1e-41
At5g25110 [T] KOG0583 Serine/threonine protein kinase 168 2e-41
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 167 2e-41
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 167 4e-41
At4g30960 [T] KOG0583 Serine/threonine protein kinase 165 1e-40
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 164 3e-40
At2g26980 [T] KOG0583 Serine/threonine protein kinase 164 3e-40
At4g18700 [T] KOG0583 Serine/threonine protein kinase 163 6e-40
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 162 7e-40
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 162 7e-40
At5g45820 [T] KOG0583 Serine/threonine protein kinase 162 7e-40
At1g29230 [T] KOG0583 Serine/threonine protein kinase 162 1e-39
7302050 [T] KOG0986 G protein-coupled receptor kinase 162 1e-39
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 161 2e-39
At4g24400 [T] KOG0583 Serine/threonine protein kinase 161 2e-39
At5g10930 [T] KOG0583 Serine/threonine protein kinase 160 4e-39
At5g39440 [T] KOG0583 Serine/threonine protein kinase 159 8e-39
At2g30360 [T] KOG0583 Serine/threonine protein kinase 158 2e-38
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 157 2e-38
At5g45810 [T] KOG0583 Serine/threonine protein kinase 157 3e-38
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 4e-38
7297776 [D] KOG0580 Serine/threonine protein kinase 157 4e-38
At5g07070 [T] KOG0583 Serine/threonine protein kinase 156 5e-38
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 156 7e-38
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 156 7e-38
At3g01090 [T] KOG0583 Serine/threonine protein kinase 156 7e-38
CE28643 [T] KOG0583 Serine/threonine protein kinase 155 9e-38
At5g35410 [T] KOG0583 Serine/threonine protein kinase 155 9e-38
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 155 1e-37
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 155 1e-37
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 154 3e-37
At5g01810 [T] KOG0583 Serine/threonine protein kinase 154 3e-37
At1g01140 [T] KOG0583 Serine/threonine protein kinase 154 3e-37
At3g29160 [T] KOG0583 Serine/threonine protein kinase 153 4e-37
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 153 6e-37
At2g34180 [T] KOG0583 Serine/threonine protein kinase 153 6e-37
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 152 8e-37
CE07458 [T] KOG0583 Serine/threonine protein kinase 152 8e-37
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 152 1e-36
CE00847 [T] KOG0583 Serine/threonine protein kinase 152 1e-36
At5g01820 [T] KOG0583 Serine/threonine protein kinase 151 2e-36
At4g14580 [T] KOG0583 Serine/threonine protein kinase 150 3e-36
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 150 5e-36
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 150 5e-36
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 149 6e-36
7290150 [T] KOG0583 Serine/threonine protein kinase 149 6e-36
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 149 1e-35
CE01554 [T] KOG0986 G protein-coupled receptor kinase 148 1e-35
At5g58380 [T] KOG0583 Serine/threonine protein kinase 148 2e-35
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 147 2e-35
At5g57630 [T] KOG0583 Serine/threonine protein kinase 146 5e-35
At3g23000 [T] KOG0583 Serine/threonine protein kinase 146 5e-35
At2g38490 [T] KOG0583 Serine/threonine protein kinase 146 5e-35
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 146 5e-35
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 146 7e-35
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 145 9e-35
YDR477w [T] KOG0583 Serine/threonine protein kinase 145 1e-34
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 145 1e-34
7299437 [R] KOG0586 Serine/threonine protein kinase 144 3e-34
At4g40010 [T] KOG0583 Serine/threonine protein kinase 144 4e-34
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 143 5e-34
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 143 5e-34
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 143 5e-34
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 143 6e-34
CE27768 [R] KOG0586 Serine/threonine protein kinase 143 6e-34
CE23838 [R] KOG0586 Serine/threonine protein kinase 143 6e-34
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 142 8e-34
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 142 1e-33
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 142 1e-33
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 141 2e-33
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 141 2e-33
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 141 2e-33
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 141 2e-33
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 140 3e-33
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 140 3e-33
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 140 4e-33
7290249 [R] KOG0586 Serine/threonine protein kinase 140 5e-33
YKL101w [D] KOG0588 Serine/threonine protein kinase 139 7e-33
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 139 9e-33
CE28218 [D] KOG0588 Serine/threonine protein kinase 139 9e-33
At2g20040 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 139 9e-33
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 139 1e-32
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 139 1e-32
At3g17510 [T] KOG0583 Serine/threonine protein kinase 139 1e-32
YPL141c [T] KOG0583 Serine/threonine protein kinase 138 2e-32
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 138 2e-32
YOR233w [T] KOG0583 Serine/threonine protein kinase 137 3e-32
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 137 3e-32
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 137 3e-32
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 137 3e-32
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 137 4e-32
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 137 4e-32
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 137 4e-32
7294217 [D] KOG0588 Serine/threonine protein kinase 137 4e-32
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 137 4e-32
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 136 6e-32
CE28479 [T] KOG0583 Serine/threonine protein kinase 136 6e-32
7302464 [R] KOG0586 Serine/threonine protein kinase 136 6e-32
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 136 7e-32
CE29300 [T] KOG0694 Serine/threonine protein kinase 136 7e-32
CE29299 [T] KOG0694 Serine/threonine protein kinase 136 7e-32
7299438 [R] KOG0586 Serine/threonine protein kinase 136 7e-32
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 135 1e-31
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 135 1e-31
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 135 1e-31
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 135 1e-31
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 135 2e-31
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 134 2e-31
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 134 4e-31
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 133 6e-31
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 133 6e-31
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 132 8e-31
ECU10g0570 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 132 8e-31
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 132 8e-31
At1g78290 [T] KOG0583 Serine/threonine protein kinase 132 8e-31
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 8e-31
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 132 8e-31
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
YPL150w [T] KOG0583 Serine/threonine protein kinase 132 1e-30
YCL024w [T] KOG0583 Serine/threonine protein kinase 132 1e-30
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 132 1e-30
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 132 1e-30
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 131 2e-30
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 131 2e-30
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 131 2e-30
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 131 2e-30
7303211 [T] KOG4717 Serine/threonine protein kinase 131 2e-30
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 130 3e-30
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 130 4e-30
YDR507c [D] KOG0588 Serine/threonine protein kinase 130 5e-30
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 129 7e-30
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 129 7e-30
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 129 9e-30
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 129 9e-30
CE17284 [T] KOG0583 Serine/threonine protein kinase 129 9e-30
At5g08590 [T] KOG0583 Serine/threonine protein kinase 129 9e-30
At4g33950 [T] KOG0583 Serine/threonine protein kinase 129 9e-30
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 129 9e-30
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 129 1e-29
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 129 1e-29
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 128 2e-29
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 128 2e-29
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 128 2e-29
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 128 2e-29
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 128 2e-29
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 128 2e-29
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 128 2e-29
At1g48260 [T] KOG0583 Serine/threonine protein kinase 128 2e-29
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 127 3e-29
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 3e-29
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 127 3e-29
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 127 3e-29
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 3e-29
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 4e-29
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 6e-29
At5g63650 [T] KOG0583 Serine/threonine protein kinase 126 6e-29
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 6e-29
YLR096w [T] KOG0583 Serine/threonine protein kinase 126 8e-29
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 125 1e-28
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 1e-28
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 125 1e-28
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 125 2e-28
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 2e-28
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 2e-28
At1g60940 [T] KOG0583 Serine/threonine protein kinase 124 2e-28
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 124 3e-28
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 3e-28
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 124 3e-28
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 124 3e-28
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 124 4e-28
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 4e-28
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 4e-28
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 123 5e-28
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 5e-28
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 122 8e-28
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 122 1e-27
At2g23030 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 122 1e-27
7302570 [R] KOG0586 Serine/threonine protein kinase 121 2e-27
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 121 2e-27
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 121 2e-27
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 121 2e-27
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 121 2e-27
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 2e-27
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 121 2e-27
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 120 3e-27
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 120 3e-27
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 120 3e-27
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 3e-27
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 4e-27
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 120 4e-27
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 120 5e-27
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 120 5e-27
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 120 5e-27
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 120 5e-27
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 119 7e-27
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 119 7e-27
At1g10940 [T] KOG0583 Serine/threonine protein kinase 119 7e-27
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 119 9e-27
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 119 9e-27
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 9e-27
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 119 9e-27
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 119 1e-26
YDR122w [T] KOG0583 Serine/threonine protein kinase 119 1e-26
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 119 1e-26
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 118 2e-26
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 2e-26
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 118 2e-26
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 117 3e-26
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 117 3e-26
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 117 4e-26
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 117 4e-26
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 4e-26
7300413 [T] KOG0583 Serine/threonine protein kinase 117 4e-26
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 117 4e-26
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 117 5e-26
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 117 5e-26
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 117 5e-26
CE15235 [R] KOG0589 Serine/threonine protein kinase 117 5e-26
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 117 5e-26
At1g54510 [R] KOG0589 Serine/threonine protein kinase 117 5e-26
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 116 6e-26
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 116 6e-26
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 116 6e-26
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 116 6e-26
At3g52890 [R] KOG0610 Putative serine/threonine protein kinase 116 6e-26
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 8e-26
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 115 1e-25
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 115 1e-25
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 115 1e-25
Hs22065405 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 115 1e-25
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 115 1e-25
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 115 1e-25
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 1e-25
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 115 1e-25
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 115 1e-25
At5g55910 [R] KOG0610 Putative serine/threonine protein kinase 115 1e-25
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 115 2e-25
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 115 2e-25
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 115 2e-25
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 115 2e-25
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 115 2e-25
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 115 2e-25
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 114 2e-25
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 2e-25
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 114 3e-25
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 114 3e-25
At4g26610 [R] KOG0610 Putative serine/threonine protein kinase 114 3e-25
At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase 114 3e-25
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 114 4e-25
CE18454 [T] KOG4717 Serine/threonine protein kinase 114 4e-25
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 114 4e-25
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 113 5e-25
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 113 5e-25
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 113 5e-25
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 113 5e-25
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 113 5e-25
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 113 7e-25
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 113 7e-25
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 113 7e-25
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 7e-25
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 112 9e-25
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 112 9e-25
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 112 9e-25
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 112 9e-25
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 112 1e-24
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 112 1e-24
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 112 1e-24
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 112 1e-24
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 112 1e-24
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 1e-24
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 112 1e-24
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 112 1e-24
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 112 1e-24
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 112 1e-24
CE17343 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
At5g66880 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 1e-24
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 112 1e-24
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 111 2e-24
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 111 2e-24
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 111 2e-24
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 111 2e-24
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 111 2e-24
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 111 2e-24
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 111 2e-24
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 111 2e-24
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 111 2e-24
At1g79250 [R] KOG0610 Putative serine/threonine protein kinase 111 3e-24
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 110 3e-24
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 110 3e-24
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 110 3e-24
CE16081 [T] KOG0583 Serine/threonine protein kinase 110 3e-24
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 110 3e-24
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 3e-24
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 110 4e-24
At1g16440 [R] KOG0610 Putative serine/threonine protein kinase 110 4e-24
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 110 6e-24
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 6e-24
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 110 6e-24
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 110 6e-24
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 110 6e-24
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 110 6e-24
7297080 [T] KOG0583 Serine/threonine protein kinase 110 6e-24
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 109 7e-24
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 109 7e-24
At5g47750 [R] KOG0610 Putative serine/threonine protein kinase 109 7e-24
At5g40030 [R] KOG0610 Putative serine/threonine protein kinase 109 7e-24
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 7e-24
At3g04810 [R] KOG0589 Serine/threonine protein kinase 109 7e-24
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 7e-24
At2g36350 [R] KOG0610 Putative serine/threonine protein kinase 109 7e-24
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 109 1e-23
At5g03640 [R] KOG0610 Putative serine/threonine protein kinase 109 1e-23
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 108 1e-23
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 1e-23
At2g44830 [R] KOG0610 Putative serine/threonine protein kinase 108 1e-23
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 1e-23
At5g28290 [R] KOG0589 Serine/threonine protein kinase 108 2e-23
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 108 2e-23
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 108 2e-23
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 108 2e-23
At3g20860 [R] KOG0589 Serine/threonine protein kinase 108 2e-23
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 108 2e-23
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 107 3e-23
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 107 3e-23
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 107 3e-23
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 107 3e-23
CE23001 [R] KOG0589 Serine/threonine protein kinase 107 3e-23
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 107 3e-23
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 3e-23
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 107 3e-23
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 583 bits (1504), Expect = e-166
Identities = 276/325 (84%), Positives = 294/325 (89%)
Query: 131 LKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHT 190
L+ R TSGKY+L DFQILRTLGTGSFGRVHL+RSNHNGRFYA+ EHT
Sbjct: 74 LQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHT 133
Query: 191 NDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA 250
NDER MLSIVSHPFIIRMWGTFQDSQQ+FM+MDYIEGGELFSLLRKSQRFPNPVAKFYAA
Sbjct: 134 NDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA 193
Query: 251 EVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPE 310
EVCLALEYLHSK IIYRDLKPENILLDKNGHIK+TDFGFAKYVPDVTYTLCGTPDYIAPE
Sbjct: 194 EVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPE 253
Query: 311 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDL 370
VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFY+SNT+KTYENILNA ++FPPFFH DAQDL
Sbjct: 254 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDL 313
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQY 430
+ KLITRDLS+RLGNLQNGSEDVKNHPWF+EV+WEKLL + IETPYEPPIQ GQGDTSQ+
Sbjct: 314 LKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQF 373
Query: 431 DRYPEEEVNYGIQGEDPYHSIFTNF 455
DRYPEEE NYGIQGEDPY + F
Sbjct: 374 DRYPEEEFNYGIQGEDPYMDLMKEF 398
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 569 bits (1466), Expect = e-162
Identities = 266/324 (82%), Positives = 291/324 (89%)
Query: 132 KARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTN 191
+ARVT G +FQILRTLGTGSFGRVHL+RS HNGR+YAM EHTN
Sbjct: 74 QARVTVGSIVYKNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTN 133
Query: 192 DERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 251
DER MLSIV+HPFIIRMWGTFQD+QQ+FMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAE
Sbjct: 134 DERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 193
Query: 252 VCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEV 311
VCLALEYLHSK IIYRDLKPENILLDKNGHIK+TDFGFAKYVPDVTYTLCGTPDYIAPEV
Sbjct: 194 VCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEV 253
Query: 312 VSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
VSTKPYNKS+DWWSFG+LIYEMLAGYTPFYDSNT+KTYE ILNA +RFPPFF+ D +DL+
Sbjct: 254 VSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLL 313
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
S+LITRDLSQRLGNLQNG+EDVKNHPWF EVVWEKLL +NIETPYEPPIQ GQGDTSQ+D
Sbjct: 314 SRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFD 373
Query: 432 RYPEEEVNYGIQGEDPYHSIFTNF 455
+YPEE++NYG+QGEDPY +F +F
Sbjct: 374 KYPEEDINYGVQGEDPYADLFRDF 397
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 509 bits (1310), Expect = e-144
Identities = 236/324 (72%), Positives = 274/324 (83%)
Query: 132 KARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTN 191
K+ V+ GKY L+DFQI+RTLGTGSFGRVHLVRS HNGR+YA+ EHTN
Sbjct: 57 KSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTN 116
Query: 192 DERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 251
DER ML +V HPF+IRMWGTFQD++ +FM+MDYIEGGELFSLLRKSQRFPNPVAKFYAAE
Sbjct: 117 DERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 176
Query: 252 VCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEV 311
V LALEYLH+ IIYRDLKPENILLD+NGHIK+TDFGFAK V VT+TLCGTPDYIAPEV
Sbjct: 177 VILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEV 236
Query: 312 VSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
++TKPYNKSVDWWS GVLIYEMLAGYTPFYD+ +KTYE IL V +PP+FH D DL+
Sbjct: 237 ITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLL 296
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
SKLIT DL++R+GNLQ+GS D+K HPWFSEVVWE+LL K+IETPYEPPI +G GDTS +D
Sbjct: 297 SKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFD 356
Query: 432 RYPEEEVNYGIQGEDPYHSIFTNF 455
+YPEE+++YGIQG+DPY F +F
Sbjct: 357 QYPEEQLDYGIQGDDPYAEYFQDF 380
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 392 bits (1008), Expect = e-109
Identities = 184/321 (57%), Positives = 231/321 (71%), Gaps = 1/321 (0%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
T +Y + DF L+TLGTGSFGRVHLV+SNHN +YA+ EHT DER
Sbjct: 192 TKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERY 251
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+LS V HPFI +WGTFQD++ LFM+MD+ EGGELFSLLRK RFP VAKFYAAEV LA
Sbjct: 252 ILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILA 311
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT-YTLCGTPDYIAPEVVST 314
L+YLH I+YRDLKPEN+LLD+ GH+K+ DFGFAK V TLCGTPDY+APE++S
Sbjct: 312 LDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPEIISL 371
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKL 374
KPYNK+ DWWS G+LI+EMLAGY PFY N +K YENIL V +P +F + DL+S L
Sbjct: 372 KPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHL 431
Query: 375 ITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYP 434
+ RD++ R GNL++GS D+ HPWF ++ W+K+L + IE PY PPIQAG GD+SQ+D Y
Sbjct: 432 LQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDAYA 491
Query: 435 EEEVNYGIQGEDPYHSIFTNF 455
+ +YG + + SIF +F
Sbjct: 492 DVATDYGTSEDPEFTSIFKDF 512
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 319 bits (817), Expect = 6e-87
Identities = 151/316 (47%), Positives = 212/316 (66%), Gaps = 1/316 (0%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
Y+L DF L T+GTG+FGRVHLV+ F+A+ +H ++E+++L
Sbjct: 44 YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKE 103
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
VSHPF+IR++ T+ D + L+M+M+Y+ GGELFS LR RF + FY+AE+ A+EYL
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
HSK I+YRDLKPENILLD++GHIKLTDFGFAK + D T+TLCGTP+Y+APEV+ +K + +
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGR 223
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+VDWW+ G+LI+EML+G+ PF+D N Y+ IL + FP +DLI KL+ D
Sbjct: 224 AVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDR 283
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEVN 439
++RLGN++NG+ DVK+H WF V WE + + ++ P P I AG GDTS ++ YPE + +
Sbjct: 284 TRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKI-AGDGDTSNFETYPENDWD 342
Query: 440 YGIQGEDPYHSIFTNF 455
IF NF
Sbjct: 343 TAAPVPQKDLEIFKNF 358
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 318 bits (814), Expect = 1e-86
Identities = 148/301 (49%), Positives = 206/301 (68%), Gaps = 1/301 (0%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L F+ ++TLGTGSFGRV LV+ G YAM EHT +E+ +L V+
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
PF++++ +F+D+ L+M+M+Y+ GGE+FS LR+ RF P A+FYAA++ L EYLHS
Sbjct: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 321
+IYRDLKPEN+L+D+ G+I++TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+V
Sbjct: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
DWW+ GVLIYEM AGY PF+ I+ YE I++ VRFP F SD +DL+ L+ DL++
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTK 280
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEVNYG 441
R GNL+NG D+KNH WF+ W + + +E P+ P + G GDTS +D Y EEE+
Sbjct: 281 RFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVS 339
Query: 442 I 442
I
Sbjct: 340 I 340
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 315 bits (807), Expect = 9e-86
Identities = 148/307 (48%), Positives = 205/307 (66%), Gaps = 1/307 (0%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
T L DF+ +TLGTGSFGRV LV+ ++YAM EHT +E+
Sbjct: 35 TQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKR 94
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+L V+ PF++R+ F+D+ L+M+M+Y+ GGE+FS LR+ RF P A+FYAA++ L
Sbjct: 95 ILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTK 315
EYLHS +IYRDLKPEN+L+D G+I++TDFGFAK V T+TLCGTP+Y+APE++ +K
Sbjct: 155 FEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSK 214
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
YNK+VDWW+ GVLIYEM AGY PF+ I+ YE I++ VRFP F SD +DL+ L+
Sbjct: 215 GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPE 435
DL++R GNL+NG D+K H WF+ W + + +E P+ P + G GDTS +D Y E
Sbjct: 275 QVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFR-GSGDTSNFDDYEE 333
Query: 436 EEVNYGI 442
E++ I
Sbjct: 334 EDIRVSI 340
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 312 bits (799), Expect = 8e-85
Identities = 148/314 (47%), Positives = 207/314 (65%), Gaps = 3/314 (0%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF ++TLGTGSFGRV LV+ +G +YAM EHT +E+ +L +
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAID 108
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
PF++ M +F+D+ L+M++++I GGE+FS LR+ RF P ++FYAA++ LA EYLHS
Sbjct: 109 FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHS 168
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 321
+IYRDLKPEN+L+D G++K+TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+V
Sbjct: 169 LDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 228
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
DWW+ GVLIYEM AGY PF+ I+ YE I++ V+FP F ++ +DL+ L+ DL++
Sbjct: 229 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTK 288
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEVNYG 441
R GNL+NG D+KNH WF W + K IE P+ P + G GD S +D Y EE +
Sbjct: 289 RYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCR-GPGDASNFDDYEEEPLR-- 345
Query: 442 IQGEDPYHSIFTNF 455
I G + F F
Sbjct: 346 ISGTEKCAKEFAEF 359
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 303 bits (775), Expect = 5e-82
Identities = 143/296 (48%), Positives = 199/296 (66%), Gaps = 1/296 (0%)
Query: 141 ALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
AL DF+ ++TLGTGSFGRV +V+ +YAM EHT +E+ +L +
Sbjct: 42 ALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI 101
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
PF++ + F+D+ L+M+++Y+ GGE+FS LRK RF P ++FYAA++ LA EYLH
Sbjct: 102 QFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLH 161
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKS 320
+IYRDLKPEN+L+D G++K+TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+
Sbjct: 162 YLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKA 221
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VDWW+ GVL+YEM AGY PF+ I+ YE I++ VRFP F SD +DL+ L+ DL+
Sbjct: 222 VDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLT 281
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
+R GNL+ G D+KN WF+ W + K IE P+ P + G GDTS +D Y EE
Sbjct: 282 KRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCK-GPGDTSNFDDYEEE 336
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 298 bits (762), Expect = 1e-80
Identities = 141/298 (47%), Positives = 198/298 (66%), Gaps = 1/298 (0%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ LRTLG GSFGRV LVR G YAM EH +E+ +L + PF
Sbjct: 44 FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPF 103
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++++ +F+D+ L+++M+Y+ GGE+FS L++ RF P A FYAA+V LA++YLHS +
Sbjct: 104 LVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDL 163
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWW 324
I+RDLKPEN+L+D+ G++++TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+VDWW
Sbjct: 164 IHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWW 223
Query: 325 SFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQRLG 384
+ GVLIYEM G+ PFY I+ YE I++ VRFP SD + L+ L+ DL++R G
Sbjct: 224 ALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFG 283
Query: 385 NLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEVNYGI 442
NL+NG D+KNH WF+ W + K +E P+ P G GD S +D Y EEE+ I
Sbjct: 284 NLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPK-YTGPGDASNFDDYEEEELRISI 340
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 295 bits (754), Expect = 1e-79
Identities = 143/327 (43%), Positives = 202/327 (61%), Gaps = 13/327 (3%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF ++TLGTGSFGRV LV+ +G +YAM EHT +E+ +L +
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAID 108
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
PF++ M +F+D+ L+M++++I GGE+FS LR+ RF P ++FYAA++ LA EYLHS
Sbjct: 109 FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHS 168
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 321
+IYRDLKPEN+L+D G++K+TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+V
Sbjct: 169 LDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 228
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
DWW+ GVLIYEM AGY PF+ I+ YE I++ V+FP F ++ +DL+ L+ DL++
Sbjct: 229 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTK 288
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETP-----------YEP--PIQAGQGDTS 428
R GNL+NG D+KNH WF W + K I P +E P G DT
Sbjct: 289 RYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPPSFSKGESNGRLFEALYPRVDGPADTR 348
Query: 429 QYDRYPEEEVNYGIQGEDPYHSIFTNF 455
+ +E + I +F F
Sbjct: 349 HFVEEVQEPTEFVIAATPQLEELFVEF 375
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 290 bits (743), Expect = 2e-78
Identities = 134/301 (44%), Positives = 198/301 (65%), Gaps = 1/301 (0%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
T ++L + + T+G G+FGRV L R G YA+ +H ++E+
Sbjct: 54 TRESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKR 113
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+L + HPFI++M+ + +DS L+MIM+++ GGE+FS LR S+ F N +A+FYA+E+ A
Sbjct: 114 VLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCA 173
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTK 315
LEY+HS GI+YRDLKPEN++L K GHIK+ DFGFAK + D TYT+CGTPDY+APE ++
Sbjct: 174 LEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGTPDYLAPESLART 233
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
+NK VDWW+ G+LIYEM+ G PF T + Y+ I+ ++FP F+ A+DL+ KL+
Sbjct: 234 GHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVKKLL 293
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPE 435
D +QR+G ++NG++DVK+H WF +V W+ L +E P P + GDT +D Y E
Sbjct: 294 EVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLY-HPGDTGNFDDYEE 352
Query: 436 E 436
+
Sbjct: 353 D 353
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 269 bits (687), Expect = 7e-72
Identities = 120/249 (48%), Positives = 177/249 (70%), Gaps = 1/249 (0%)
Query: 188 EHTNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKF 247
+H ++E+ +L + HPFI++M+ + +DS L+MIM+++ GGE+FS LR S+ F N +A+F
Sbjct: 5 QHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARF 64
Query: 248 YAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYI 307
YA+E+ ALEY+HS GI+YRDLKPEN++L K GHIK+ DFGFAK + D TYT+CGTPDY+
Sbjct: 65 YASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGTPDYL 124
Query: 308 APEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDA 367
APE ++ +NK VDWW+ G+LIYEM+ G PF T + Y+ I+ ++FP F+ A
Sbjct: 125 APESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAA 184
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDT 427
+DL+ KL+ D +QR+G ++NG++DVK+H WF +V W+ L +E P P + GDT
Sbjct: 185 KDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLY-HPGDT 243
Query: 428 SQYDRYPEE 436
+D Y E+
Sbjct: 244 GNFDDYEED 252
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 269 bits (687), Expect = 7e-72
Identities = 127/297 (42%), Positives = 189/297 (62%), Gaps = 3/297 (1%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L D++I TLG+GSFG+V LVR +G +YA H E+N+L ++
Sbjct: 44 LDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMT 103
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
P + + +++D L++++ I GGELF+ RK ++F A+FYAA+V LALEYLH
Sbjct: 104 FPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHH 163
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 321
++YRDLKPENI++DKNG++K+TDFGFAK V T TLCGTP+Y+ PE++ +KPY SV
Sbjct: 164 CSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQSKPYGTSV 223
Query: 322 DWWSFGVLIYEMLAGYTPF--YDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
DWW+FGVL++E +AG++PF ++ + + Y I A + P +F + L+ L+ DL
Sbjct: 224 DWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDL 283
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
S+R GNL NG+ D+K H WF +V W LL + + PY P I + D S +D+ ++
Sbjct: 284 SKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNI-SNPEDISNFDKVSDK 339
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 254 bits (649), Expect = 2e-67
Identities = 127/290 (43%), Positives = 182/290 (61%), Gaps = 6/290 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F++L+ +G GSFG+V VR R YA+ +HT ER +L+ V++PF
Sbjct: 230 FELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNNPF 289
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+ + +FQ +L++++ ++ GGELF L++ F AKFY AE+ +ALE LH +
Sbjct: 290 IVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNV 349
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPYNKSV 321
IYRDLKPENILLD GHI L DFG K D T T CGTP+Y+APE++ Y K V
Sbjct: 350 IYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYTKVV 409
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
DWW+ GVL+YEM+ G PFYD N + Y IL P+RFP A+DL+S L+TR +
Sbjct: 410 DWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRAPEK 469
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
RLG+ G++++KNHP+F ++ W+KL K I+ P++P +++ DTS +D
Sbjct: 470 RLGS--GGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAI-DTSNFD 516
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 253 bits (646), Expect = 4e-67
Identities = 128/291 (43%), Positives = 182/291 (61%), Gaps = 6/291 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF +L+ +G GSFG+V VR + YA+ HT ER +L+ V P
Sbjct: 346 DFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCP 405
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
FI+ + +FQ ++L+ ++ +I GGELF L+K RF A+FY AE+ AL+ LH
Sbjct: 406 FIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLD 465
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPYNKS 320
++YRDLKPENILLD GHI L DFG K D T T CGTP+Y+APE++ Y K+
Sbjct: 466 VVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKA 525
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VDWW+ GVL+YEML G P+YD + K Y+ IL P+ FP F DA+DL+ L++RD +
Sbjct: 526 VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPT 585
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+RLG NG+++++NHP+FS++ W++LL K PY+P + + DTS +D
Sbjct: 586 RRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAV-SNSMDTSNFD 633
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 249 bits (636), Expect = 6e-66
Identities = 131/309 (42%), Positives = 189/309 (60%), Gaps = 8/309 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN-MLSIVSH 202
DF L+ +G GSFG+V L R FYA+ +H ERN +L V H
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 203 PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
PF++ + +FQ + +L+ ++DYI GGELF L++ + F P A+FYAAE+ AL YLHS
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYNK 319
I+YRDLKPENILLD GHI LTDFG K + T T CGTP+Y+APEV+ +PY++
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+VDWW G ++YEML G PFY NT + Y+NILN P++ P + A+ L+ L+ +D
Sbjct: 277 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 336
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD-RYPEEEV 438
++RLG ++ ++K+H +FS + W+ L+ K I P+ P + +G + +D + EE V
Sbjct: 337 TKRLG-AKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNV-SGPNELRHFDPEFTEEPV 394
Query: 439 NYGIQGEDP 447
I G+ P
Sbjct: 395 PNSI-GKSP 402
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 247 bits (631), Expect = 2e-65
Identities = 124/292 (42%), Positives = 183/292 (62%), Gaps = 6/292 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF +L+ +G GSFG+V VR + YA+ HT ER +L+ V P
Sbjct: 343 DFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCP 402
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
FI+ + +FQ ++L++++ +I GGELF L+ RF ++FY AE+ AL+ LH
Sbjct: 403 FIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLD 462
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPYNKS 320
+IYRDLKPENILLD GHI L DFG K D T T CGTP+Y+APE++ + Y K+
Sbjct: 463 VIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKT 522
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VDWW+ G+L+YEM+ G P+YD N Y+ IL P+ FP F A+DL+ L++RD S
Sbjct: 523 VDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPS 582
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
+RLG NG+++++NHP+F ++ W+KLL K PY+P +++ + DT+ +D+
Sbjct: 583 RRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKS-EIDTANFDQ 631
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 247 bits (630), Expect = 3e-65
Identities = 124/294 (42%), Positives = 181/294 (61%), Gaps = 8/294 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXX-XEHTNDERNMLSIV 200
F++LR LG G +G+V VR + G+ +AM HT ERN+L V
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
HPFI+ + FQ +L++I++Y+ GGELF L + F A FY AE+ +AL +LH
Sbjct: 151 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 210
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPY 317
KGIIYRDLKPENI+L+ GH+KLTDFG K + VT+T CGT +Y+APE++ +
Sbjct: 211 QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGH 270
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
N++VDWWS G L+Y+ML G PF N KT + IL + PP+ +A+DL+ KL+ R
Sbjct: 271 NRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKR 330
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+ + RLG + +V+ HP+F + WE+LL + +E P++P +Q+ + D SQ+D
Sbjct: 331 NAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQS-EEDVSQFD 383
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 246 bits (629), Expect = 4e-65
Identities = 128/304 (42%), Positives = 184/304 (60%), Gaps = 7/304 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN-MLSIVSH 202
DF L+ +G G++G+V L + +G FYA+ H ER+ +L V H
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 203 PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
PF++ + +FQ ++L+ ++DY+ GGELF L++ +RF P A+FYAAEV A+ YLHS
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
IIYRDLKPENILLD GH+ LTDFG K D T T CGTP+Y+APEV+ +PY++
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+VDWW G ++YEML G PFY + + YENIL+ P++ P A DL+ L+ +D
Sbjct: 274 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 333
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD-RYPEEEV 438
QRLG+ + E +KNH +FS + W+ L K + P+ P + G D +D + +E V
Sbjct: 334 RQRLGSKADFLE-IKNHVFFSPINWDDLYHKRLTPPFNPNV-TGPADLKHFDPEFTQEAV 391
Query: 439 NYGI 442
+ I
Sbjct: 392 SKSI 395
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 245 bits (626), Expect = 9e-65
Identities = 121/293 (41%), Positives = 181/293 (61%), Gaps = 6/293 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNML-SIVSH 202
DF L T+G GSFGRV+ VR + YAM +H ERN+L + H
Sbjct: 93 DFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFKH 152
Query: 203 PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
PF++ + +FQ+ ++L+ ++D++ GGELFS L++ + F ++FYAAE+ AL YLH K
Sbjct: 153 PFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEK 212
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
IIYRDLKPEN+LLD G++ LTDFG K T T CGTP+Y+APE++ KPY+K
Sbjct: 213 NIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDK 272
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+VDWW G ++YEM+ G PFY + + Y+ I+N P+R +LI+ L+ +D
Sbjct: 273 TVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDR 332
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
S+RLG+ +N D+++HP+F V W+KLL + ++ P+ P ++ DTS +
Sbjct: 333 SKRLGH-RNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAM-DTSNISK 383
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 245 bits (625), Expect = 1e-64
Identities = 124/304 (40%), Positives = 184/304 (59%), Gaps = 7/304 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN-MLSIVSH 202
DF L+ +G GSFG+V L + +G+ YA+ +H ERN +L V H
Sbjct: 43 DFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 102
Query: 203 PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
PF++ + +FQ +++L+ ++D++ GGELF L++ + FP A+FYAAE+ AL YLHS
Sbjct: 103 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 162
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
I+YRDLKPENIL+D GH+ LTDFG K + D T T CGTP+Y+APEV+ +PY+
Sbjct: 163 KIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 222
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+VDWW G ++YEML G PFY + + Y+NIL+ P+ P A ++ +L+ +D
Sbjct: 223 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLRAWSILEELLEKDR 282
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD-RYPEEEV 438
RLG ++ E ++NHP+F + W L+ K I P+ P + AG D +D + EE V
Sbjct: 283 QNRLGAKEDFLE-IQNHPFFESLSWADLVQKKIPPPFNPNV-AGPDDIRNFDTAFTEETV 340
Query: 439 NYGI 442
Y +
Sbjct: 341 PYSV 344
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 244 bits (622), Expect = 3e-64
Identities = 125/294 (42%), Positives = 178/294 (60%), Gaps = 8/294 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXX-XEHTNDERNMLSIV 200
F++LR LG G +G+V VR + G+ YAM HT ERN+L V
Sbjct: 80 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 139
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
HPFI+ + FQ +L++I++ + GGELF+ L + F A FY AE+ LAL +LH
Sbjct: 140 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 199
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPY 317
S+GIIYRDLKPENI+L GHIKLTDFG K + VT+T CGT +Y+APE++ +
Sbjct: 200 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 259
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
N++VDWWS G L+Y+ML G PF N KT + I+ + PP+ DA+DL+ K + R
Sbjct: 260 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 319
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+ SQR+G + DV+ HP+F + W+ LL ++ P+ P +Q+ + D SQ+D
Sbjct: 320 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQS-EEDVSQFD 372
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 243 bits (621), Expect = 3e-64
Identities = 111/221 (50%), Positives = 156/221 (70%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
Y L D L T+GTG+FGRVHLV+ F+A+ +H ++E+++L
Sbjct: 44 YRLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKE 103
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
VSHPF+IR++ T+ + + L+M+M+Y+ GGELFS LR F + FY+AE+ A+EYL
Sbjct: 104 VSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYL 163
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
HSK I+YRDLKPENILLD++GHIKLTDFGFAK + D T+TLCGTP+Y+APEV+ +K + +
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGR 223
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP 360
+VDWW+ G+LI+EML+G+ PF+D N Y+ IL + FP
Sbjct: 224 AVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFP 264
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 242 bits (618), Expect = 7e-64
Identities = 137/311 (44%), Positives = 187/311 (60%), Gaps = 10/311 (3%)
Query: 129 STLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXE 188
+T+ ++ Y DF L+ +G G+FG+V+LVR R YAM
Sbjct: 250 NTVFQPLSQHSYGPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVA 309
Query: 189 HTNDERNML---SIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVA 245
HT ER++L S PFI+ + +FQ + L+++ DY+ GGELF L+KS RFP A
Sbjct: 310 HTVGERDILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERA 369
Query: 246 KFYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCG 302
KFY AE+ LAL+ LH +GI+YRDLKPENILLD GHI L DFG +K V T T CG
Sbjct: 370 KFYIAELLLALQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCG 429
Query: 303 TPDYIAPEVVSTKP-YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPP 361
T DY+APEV+ + Y+ VD+WS GVL+YEM G++PFY NT + Y+NI+ VRFP
Sbjct: 430 TTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPR 489
Query: 362 FFHS-DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPI 420
S +A+DLI L+ R+ RLG E+V HP+F + W+KL K I P++P +
Sbjct: 490 GLLSVEARDLIKLLLNRNPKHRLG-AHGDVEEVMKHPFFDGIDWKKLAAKEISPPFKPIV 548
Query: 421 QAGQGDTSQYD 431
+ G+ D S +D
Sbjct: 549 E-GEIDVSNFD 558
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 241 bits (616), Expect = 1e-63
Identities = 132/322 (40%), Positives = 194/322 (59%), Gaps = 15/322 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
F++L+ LG GSFG+V LVR +G YAM T ER++L+ V+
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVR-TKMERDILADVN 120
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HPF++++ FQ +L++I+D++ GG+LF+ L K F KFY AE+ L L++LHS
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYN 318
GIIYRDLKPENILLD+ GHIKLTDFG +K D Y+ CGT +Y+APEVV+ + ++
Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS 240
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
S DWWS+GVL++EML G PF + +T IL A + P F ++AQ L+ L R+
Sbjct: 241 HSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRN 300
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD-----RY 433
+ RLG+ +G+E++K H ++S + W KL + I+ P++P + A DT +D R
Sbjct: 301 PANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAV-AQPDDTFYFDTEFTSRT 359
Query: 434 PEEEVNYGIQGEDPYHSIFTNF 455
P++ + GI H +F F
Sbjct: 360 PKD--SPGIPPSAGAHQLFRGF 379
Score = 123 bits (308), Expect = 6e-28
Identities = 76/222 (34%), Positives = 124/222 (55%), Gaps = 23/222 (10%)
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+L HP II + + D + ++++ + + GGEL + + + F A F +
Sbjct: 463 LLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKT 522
Query: 256 LEYLHSKGIIYRDLKPENIL-LDKNGH---IKLTDFGFAKYV---PDVTYTLCGTPDYIA 308
+EYLHS+G+++RDLKP NIL +D++G+ +++ DFGFAK + + T C T +++A
Sbjct: 523 VEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVA 582
Query: 309 PEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHS--- 365
PEV+ + Y++ D WS G+L+Y MLAGYTPF + + T E IL + F S
Sbjct: 583 PEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPS-DTPEEILTR-IGSGKFTLSGGN 640
Query: 366 ------DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
A+DL+SK++ D QRL ++ V HPW ++
Sbjct: 641 WNTVSETAKDLVSKMLHVDPHQRL-----TAKQVLQHPWVTQ 677
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 241 bits (615), Expect = 2e-63
Identities = 124/301 (41%), Positives = 180/301 (59%), Gaps = 6/301 (1%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
+S + + +F+ +R LG GSFG+V L R G YA+ E T E+
Sbjct: 345 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKR 404
Query: 196 MLSIV-SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCL 254
+LS+ +HPF+ +++ FQ +LF +M+++ GG+L ++KS+RF A+FYAAE+
Sbjct: 405 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIIS 464
Query: 255 ALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEV 311
AL +LH KGIIYRDLK +N+LLD GH KL DFG K T T CGTPDYIAPE+
Sbjct: 465 ALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEI 524
Query: 312 VSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
+ Y +VDWW+ GVL+YEML G+ PF N +E ILN V +P + H DA ++
Sbjct: 525 LQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGIL 584
Query: 372 SKLITRDLSQRLGNL-QNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQY 430
+T++ + RLG+L Q G + HP+F E+ W +L + IE P+ P I++ + D S +
Sbjct: 585 KSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSRE-DVSNF 643
Query: 431 D 431
D
Sbjct: 644 D 644
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 241 bits (615), Expect = 2e-63
Identities = 129/300 (43%), Positives = 179/300 (59%), Gaps = 6/300 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVR-SNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
L DF I+ TLG G FGRV LV+ + + +AM EH E+ ++
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
FI+R++ TF+DS+ L+M+M+ GGEL+++LR F + +FY A V A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV--PDVTYTLCGTPDYIAPEVVSTKPYN 318
SKGIIYRDLKPEN++LD G+ KL DFGFAK + T+T CGTP+Y+APE++ K ++
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNA--PVRFPPFFHSDAQDLISKLIT 376
S D+WS G+L+YE+L G PF + +KTY IL + FP +A +LI KL
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 377 RDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
+ S+RLGNL+NG +D++ H WF WE L K TP P A DTS +D +PE+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLR-KGTLTPPIIPSVASPTDTSNFDSFPED 670
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 239 bits (611), Expect = 5e-63
Identities = 127/320 (39%), Positives = 189/320 (58%), Gaps = 16/320 (5%)
Query: 144 DFQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXX-XEHTNDERNMLSI 199
DFQ+L+ LG G +G+V VR + NG+ +AM HT ERN+L
Sbjct: 82 DFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNILEA 141
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
V PFI + FQ +L++I++Y+ GGELF L + F VAKFY +E+ ++LE+L
Sbjct: 142 VKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEHL 201
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV---PDVTYTLCGTPDYIAPEVVSTKP 316
H +GIIYRDLKPENILLD GH+KLTDFG K T+T CGT +Y+APE++
Sbjct: 202 HQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMRCG 261
Query: 317 YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLIT 376
+ K+VDWWS G L+++ML G PF N KT + IL + P + ++A+DLI KL+
Sbjct: 262 HGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKLLK 321
Query: 377 RDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD-RYPE 435
R + RLG + +E++K+H +F W + + +E P++P I+ + DTS +D R+ +
Sbjct: 322 RHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDE-DTSLFDARFTK 380
Query: 436 E-------EVNYGIQGEDPY 448
E N+ + G++P+
Sbjct: 381 MTPVDSPCETNFSLNGDNPF 400
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 237 bits (605), Expect = 2e-62
Identities = 125/293 (42%), Positives = 182/293 (61%), Gaps = 8/293 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
F++L+ LG GSFG+V LVR +G YAM + T ERN+L+ +S
Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR-QRTKLERNILAHIS 162
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HPFI+++ FQ +L++I+D++ GG+LF+ L K F KFY AE+ LALE+LHS
Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 222
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYN 318
GI+YRDLKPENILLD +GHIK+TDFG +K D TY+ CGT +Y+APEV++ + ++
Sbjct: 223 LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 282
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+ D+WS GVL++EML G+ PF + T IL A + P F +AQ L+ L R+
Sbjct: 283 MAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRN 342
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
RLG +G E++K H +F+++ + KLL K I+ P++P + TS +D
Sbjct: 343 SQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALST-VDSTSYFD 394
Score = 103 bits (256), Expect = 7e-22
Identities = 77/274 (28%), Positives = 131/274 (47%), Gaps = 28/274 (10%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
D++IL +G G+ VH + R YA+ + T + +L H
Sbjct: 453 DYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVF------DATEEVDILLRHSHHQ 506
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVCLALEYLHS 261
F+++++ ++D ++MI + EGGEL L +KS VA A + A++YLHS
Sbjct: 507 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA-NLLNAVQYLHS 565
Query: 262 KGIIYRDLKPENILLD-KNGH---IKLTDFGFAKYVP---DVTYTLCGTPDYIAPEVVST 314
+ + +RDL NIL K+G +++ DFGFAK + T C T ++APEV+
Sbjct: 566 QQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRK 625
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFY-------DSNTIKTYENILNAPVRFPPFFHSDA 367
+ Y++S D WS GVL++ ML G TPF D + + ++ +A
Sbjct: 626 QGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEA 685
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
+DL+ K++ D ++R+ ++ H W +
Sbjct: 686 KDLVRKMLDVDPNRRV-----TAKQALQHKWIGQ 714
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 237 bits (605), Expect = 2e-62
Identities = 125/293 (42%), Positives = 182/293 (61%), Gaps = 8/293 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
F++L+ LG GSFG+V LVR +G YAM + T ERN+L+ +S
Sbjct: 47 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR-QRTKLERNILAHIS 105
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HPFI+++ FQ +L++I+D++ GG+LF+ L K F KFY AE+ LALE+LHS
Sbjct: 106 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 165
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYN 318
GI+YRDLKPENILLD +GHIK+TDFG +K D TY+ CGT +Y+APEV++ + ++
Sbjct: 166 LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 225
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+ D+WS GVL++EML G+ PF + T IL A + P F +AQ L+ L R+
Sbjct: 226 MAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRN 285
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
RLG +G E++K H +F+++ + KLL K I+ P++P + TS +D
Sbjct: 286 SQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALST-VDSTSYFD 337
Score = 103 bits (256), Expect = 7e-22
Identities = 77/274 (28%), Positives = 131/274 (47%), Gaps = 28/274 (10%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
D++IL +G G+ VH + R YA+ + T + +L H
Sbjct: 396 DYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVF------DATEEVDILLRHSHHQ 449
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVCLALEYLHS 261
F+++++ ++D ++MI + EGGEL L +KS VA A + A++YLHS
Sbjct: 450 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA-NLLNAVQYLHS 508
Query: 262 KGIIYRDLKPENILLD-KNGH---IKLTDFGFAKYVP---DVTYTLCGTPDYIAPEVVST 314
+ + +RDL NIL K+G +++ DFGFAK + T C T ++APEV+
Sbjct: 509 QQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRK 568
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFY-------DSNTIKTYENILNAPVRFPPFFHSDA 367
+ Y++S D WS GVL++ ML G TPF D + + ++ +A
Sbjct: 569 QGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEA 628
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
+DL+ K++ D ++R+ ++ H W +
Sbjct: 629 KDLVRKMLDVDPNRRV-----TAKQALQHKWIGQ 657
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 237 bits (604), Expect = 3e-62
Identities = 131/311 (42%), Positives = 184/311 (59%), Gaps = 10/311 (3%)
Query: 130 TLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEH 189
T+ + +Y DF LR +G G+FG+V+LVR N R YAM H
Sbjct: 287 TIYEHIEHVRYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTH 346
Query: 190 TNDERNML---SIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAK 246
T ERN+L S+ PFI+ + +FQ + L++I DY+ GGELF L+ RFP AK
Sbjct: 347 TLGERNILVRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAK 406
Query: 247 FYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGT 303
FY AE+ LALE+LH IIYRDLKPENILLD +GHI L DFG +K T T CGT
Sbjct: 407 FYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGT 466
Query: 304 PDYIAPEV-VSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPP- 361
+Y+APEV + K Y K VD+WS GVL++EM G++PFY + + Y NI VRFP
Sbjct: 467 TEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKG 526
Query: 362 FFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQ 421
S+ + + L+ R+ + RLG + + +E +K HP+F+++ W+ L K ++ P++P +Q
Sbjct: 527 VLSSEGRSFVRGLLNRNPNHRLGAVADTTE-LKEHPFFADINWDLLSKKKVQPPFKPNVQ 585
Query: 422 AGQGDTSQYDR 432
D S +D+
Sbjct: 586 -NDLDVSNFDK 595
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 236 bits (602), Expect = 5e-62
Identities = 125/293 (42%), Positives = 180/293 (60%), Gaps = 8/293 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
F++L+ LG GS+G+V LVR + G+ YAM + ER++L+ V+
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR-SKMERDILAEVN 117
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HPFI+++ FQ +L++I+D++ GG+LF+ L K F KFY AE+ LAL++LHS
Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 177
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYN 318
GIIYRDLKPENILLD+ GHIK+TDFG +K D Y+ CGT +Y+APEVV+ + +
Sbjct: 178 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 237
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+S DWWSFGVL++EML G PF + +T IL A + P F +AQ L+ L R+
Sbjct: 238 QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRN 297
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
RLG +G E++K HP+F + W L K I+ P++P + + DT +D
Sbjct: 298 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPE-DTFHFD 349
Score = 117 bits (293), Expect = 4e-26
Identities = 75/219 (34%), Positives = 120/219 (54%), Gaps = 23/219 (10%)
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+L HP II + + D + ++++M+ + GGEL + + + F A +
Sbjct: 460 LLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKT 519
Query: 256 LEYLHSKGIIYRDLKPENILL-DKNG---HIKLTDFGFAKYV---PDVTYTLCGTPDYIA 308
++YLHS+G+++RDLKP NIL D++G I++ DFGFAK + + T C T +++A
Sbjct: 520 MDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVA 579
Query: 309 PEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD-- 366
PEV+ + Y+ + D WS G+L+Y MLAG+TPF + T E IL A + + S
Sbjct: 580 PEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPD-DTPEEIL-ARIGSGKYALSGGN 637
Query: 367 -------AQDLISKLITRDLSQRLGNLQNGSEDVKNHPW 398
A+D++SK++ D QRL +Q V HPW
Sbjct: 638 WDSISDAAKDVVSKMLHVDPHQRLTAMQ-----VLKHPW 671
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 235 bits (600), Expect = 9e-62
Identities = 124/313 (39%), Positives = 187/313 (59%), Gaps = 7/313 (2%)
Query: 131 LKARVT--SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXE 188
LK +V S + +I+ TLG G FGRV LV+ + +AM E
Sbjct: 437 LKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQE 496
Query: 189 HTNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFY 248
H E+ +L + PFI++++ TF+D++ ++M+++ GGEL+S+LR F P +KF
Sbjct: 497 HVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFC 556
Query: 249 AAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV--PDVTYTLCGTPDY 306
A V A +YLH GIIYRDLKPEN++LD G++KL DFGFAK + T+T CGTP+Y
Sbjct: 557 VACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEY 616
Query: 307 IAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNA--PVRFPPFFH 364
+APEV+ K ++ SVD+WS G+L+YE+L G PF + + TY IL + FP
Sbjct: 617 VAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKIT 676
Query: 365 SDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQ 424
+DLI +L ++ ++RLGNL+NG D+K H W + WE L +++ +P + ++ G
Sbjct: 677 RRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELK-GP 735
Query: 425 GDTSQYDRYPEEE 437
D S +D+YP E+
Sbjct: 736 IDHSYFDKYPPEK 748
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 234 bits (598), Expect = 2e-61
Identities = 124/298 (41%), Positives = 180/298 (59%), Gaps = 9/298 (3%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K + DF + + LG GSFG+V L +F+A+ E T E+ +LS
Sbjct: 374 KLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLS 433
Query: 199 IV-SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 257
+ HPF+ M+ TFQ + LF +M+Y+ GG+L ++ +F A FYAAE+ L L+
Sbjct: 434 LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQ 493
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK--YVPDV-TYTLCGTPDYIAPEVVST 314
+LHSKGI+YRDLK +NILLDK+GHIK+ DFG K + D T T CGTPDYIAPE++
Sbjct: 494 FLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLG 553
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKL 374
+ YN SVDWWSFGVL+YEML G +PF+ + + + +I +P + +A+DL+ KL
Sbjct: 554 QKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKL 613
Query: 375 ITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
R+ +RLG D++ HP F E+ WE+L K I+ P+ P +++ D S +D+
Sbjct: 614 FVREPEKRLG----VRGDIRQHPLFREINWEELERKEIDPPFRPKVKS-PFDCSNFDK 666
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 234 bits (598), Expect = 2e-61
Identities = 117/291 (40%), Positives = 175/291 (59%), Gaps = 4/291 (1%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF L+ LG G+FG+V LVR +G++YAM HT E +L HP
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F+ + +FQ +L +M+Y+ GGELF L + + F +FY AE+ AL+YLHS
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY-VPDVT--YTLCGTPDYIAPEVVSTKPYNKS 320
I+YRDLK EN++LDK+GHIK+TDFG K + D T CGTP+Y+APEV+ Y ++
Sbjct: 267 IVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRA 326
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VDWW GV++YEM+ G PFY+ + K +E IL ++FP SDA+ L+S L+ +D +
Sbjct: 327 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPN 386
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+RLG + ++++ H +FS V W+ + K + P++P + + DT +D
Sbjct: 387 KRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV-TSETDTRYFD 436
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 234 bits (598), Expect = 2e-61
Identities = 134/322 (41%), Positives = 190/322 (58%), Gaps = 15/322 (4%)
Query: 145 FQILRTLGTGSFGRVHLVR--SNHNGR-FYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
F++L+ LG GSFG+V LV+ S + R YAM T ER++L V+
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEVN 126
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HPFI+++ FQ +L++I+D++ GG+LF+ L K F KFY AE+ LAL++LHS
Sbjct: 127 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 186
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYN 318
GIIYRDLKPENILLD+ GHIKLTDFG +K D Y+ CGT +Y+APEVV+ + +
Sbjct: 187 LGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT 246
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+S DWWSFGVL++EML G PF + +T IL A + P F +AQ L+ L R+
Sbjct: 247 QSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRN 306
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD-----RY 433
+ RLG +G E++K H +FS + W KL + I P++P + DT +D +
Sbjct: 307 PANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPE-DTFYFDPEFTAKT 365
Query: 434 PEEEVNYGIQGEDPYHSIFTNF 455
P++ + GI H +F F
Sbjct: 366 PKD--SPGIPPSANAHQLFRGF 385
Score = 118 bits (296), Expect = 2e-26
Identities = 80/234 (34%), Positives = 127/234 (54%), Gaps = 25/234 (10%)
Query: 190 TNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYA 249
T + +L HP II + + D + ++++ + ++GGEL + + + F A
Sbjct: 461 TEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVL 520
Query: 250 AEVCLALEYLHSKGIIYRDLKPENIL-LDKNGH---IKLTDFGFAKYV---PDVTYTLCG 302
+ +EYLH++G+++RDLKP NIL +D++G+ I++ DFGFAK + + T C
Sbjct: 521 FTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCY 580
Query: 303 TPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPF 362
T +++APEV+ + Y+ + D WS GVL+Y ML GYTPF + T E IL A + F
Sbjct: 581 TANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPD-DTPEEIL-ARIGSGKF 638
Query: 363 FHS---------DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKL 407
S A+DL+SK++ D QRL + V HPW V W++L
Sbjct: 639 SLSGGYWNSVSDTAKDLVSKMLHVDPHQRL-----TAALVLRHPWI--VHWDQL 685
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 233 bits (595), Expect = 3e-61
Identities = 124/306 (40%), Positives = 181/306 (58%), Gaps = 10/306 (3%)
Query: 135 VTSGKYAL--YDFQILRTLGTGSFGRVHLVRSNHN---GRFYAMXXXXXXXXXXXXX-XE 188
V GK L DF++ + LG G +G+V VR +++AM
Sbjct: 65 VNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTA 124
Query: 189 HTNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFY 248
HT ERN+L V HPFI+ + FQ +L++I++Y+ GGELF L + F FY
Sbjct: 125 HTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFY 184
Query: 249 AAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK-YVPD--VTYTLCGTPD 305
+E+ LAL +LH GIIYRDLKPENILLD GH+KLTDFG K ++ + VT+T CGT +
Sbjct: 185 LSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIE 244
Query: 306 YIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHS 365
Y+APE+++ + K+VDWWS G L+++ML G PF N KT E IL A + P +
Sbjct: 245 YMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTP 304
Query: 366 DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG 425
+A+DL+ +L+ R QRLG+ + V+ HP+F V W+ +L + +E P +P +++ +
Sbjct: 305 EARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRS-ED 363
Query: 426 DTSQYD 431
D SQ+D
Sbjct: 364 DVSQFD 369
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 233 bits (593), Expect = 6e-61
Identities = 109/290 (37%), Positives = 177/290 (60%), Gaps = 3/290 (1%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
SG + DF++L+ +G G+FG+V+ VR YAM E+ ER++
Sbjct: 132 SGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDI 191
Query: 197 LSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 256
L+ + HPFI+++ +FQ +L++++D+I GG LF L F +A+ Y AE+ A+
Sbjct: 192 LTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAV 251
Query: 257 EYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT--YTLCGTPDYIAPEVVST 314
+LH KGI++RDLKPENIL+D +GH+ LTDFG AK + T ++CGT +Y+APE+V
Sbjct: 252 SHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRG 311
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKL 374
K ++K+ DWWS G+L+YEML G PF S K + I+ ++ P F ++A L+ L
Sbjct: 312 KGHDKAADWWSVGILLYEMLTGKPPFLGSKG-KIQQKIVKDKIKLPQFLSNEAHALLKGL 370
Query: 375 ITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQ 424
+ ++ +RLG+ +G+E++K H WF + W+KL + ++ ++P + Q
Sbjct: 371 LQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQ 420
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 232 bits (592), Expect = 8e-61
Identities = 116/296 (39%), Positives = 174/296 (58%), Gaps = 4/296 (1%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K + DF L+ LG G+FG+V LVR GR+YAM HT E +L
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
HPF+ + FQ +L +M+Y GGELF L + + F A+FY AE+ ALEY
Sbjct: 206 NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEY 265
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY-VPD--VTYTLCGTPDYIAPEVVSTK 315
LHS+ ++YRD+K EN++LDK+GHIK+TDFG K + D T CGTP+Y+APEV+
Sbjct: 266 LHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDN 325
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
Y ++VDWW GV++YEM+ G PFY+ + + +E IL +RFP +A+ L++ L+
Sbjct: 326 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLL 385
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+D QRLG + +++V H +F + W+ ++ K + P++P + + DT +D
Sbjct: 386 KKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQV-TSEVDTRYFD 440
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 231 bits (590), Expect = 1e-60
Identities = 119/280 (42%), Positives = 176/280 (62%), Gaps = 9/280 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHN---GRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
F++L+ LG GSFG+V LVR G+ YAM T ER++L V+
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR-TKMERDILVEVN 131
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HPFI+++ FQ +L++I+D++ GG++F+ L K F KFY AE+ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYN 318
GI+YRDLKPENILLD+ GHIKLTDFG +K D Y+ CGT +Y+APEVV+ + ++
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+S DWWS+GVL++EML G PF + +T IL A + P F ++AQ L+ L R+
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP 418
+ RLG+ G E++K H +F+ + W+KL + ++ P++P
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKP 349
Score = 110 bits (275), Expect = 4e-24
Identities = 70/213 (32%), Positives = 111/213 (51%), Gaps = 19/213 (8%)
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HP II + F D + ++++ D ++GGEL + K + F A + ++YLH
Sbjct: 477 HPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHC 536
Query: 262 KGIIYRDLKPENIL-LDKNG---HIKLTDFGFAKYV---PDVTYTLCGTPDYIAPEVVST 314
+G+++RDLKP NIL +D++ I++ DFGFAK + + T C T +++APEV+
Sbjct: 537 QGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQ 596
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN-APVRFP------PFFHSDA 367
+ Y+ + D WS GVL Y MLAGYTPF + E +L +F A
Sbjct: 597 QGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGA 656
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFS 400
+DL+S ++ D QR +E + H W +
Sbjct: 657 KDLLSHMLHMDPHQRY-----TAEQILKHSWIT 684
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 231 bits (590), Expect = 1e-60
Identities = 116/310 (37%), Positives = 185/310 (59%), Gaps = 7/310 (2%)
Query: 128 TSTLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXX 187
+S ++V G +++DF ++ LG GSFG+V L YA+
Sbjct: 361 SSRSASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDV 420
Query: 188 EHTNDERNMLSIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAK 246
E T E+ +LS+ + HPF+ + +FQ S +LF +M+Y+ GG+L ++++++F A+
Sbjct: 421 ECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRAR 480
Query: 247 FYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGT 303
FYAAEV AL++LH +IYRDLK +NILLD GH +L DFG K ++T T CGT
Sbjct: 481 FYAAEVTCALQFLHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGT 540
Query: 304 PDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFF 363
PDYIAPE++ Y SVDWW+ GVL+YEM+AG PF N +E ILN V +P +
Sbjct: 541 PDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWL 600
Query: 364 HSDAQDLISKLITRDLSQRLGNL--QNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQ 421
+A +++ +T++ +RLG + Q G + ++ HP+F E+ W+ L + ++ P++P I+
Sbjct: 601 SKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIK 660
Query: 422 AGQGDTSQYD 431
+ + D + +D
Sbjct: 661 S-KRDANNFD 669
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 231 bits (588), Expect = 2e-60
Identities = 116/297 (39%), Positives = 176/297 (59%), Gaps = 5/297 (1%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
+ + +F+ L+ LG G+FG+V LV+ GR+YAM HT E +L
Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ 203
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
HPF+ + +FQ +L +M+Y GGELF L + + F A+FY AE+ AL+Y
Sbjct: 204 NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDY 263
Query: 259 LHS-KGIIYRDLKPENILLDKNGHIKLTDFGFAKY-VPD--VTYTLCGTPDYIAPEVVST 314
LHS K ++YRDLK EN++LDK+GHIK+TDFG K + D T CGTP+Y+APEV+
Sbjct: 264 LHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLED 323
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKL 374
Y ++VDWW GV++YEM+ G PFY+ + K +E IL +RFP +A+ L+S L
Sbjct: 324 NDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGL 383
Query: 375 ITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+ +D QRLG ++++ H +F+ +VW+ + K + P++P + + DT +D
Sbjct: 384 LKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV-TSETDTRYFD 439
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 230 bits (586), Expect = 4e-60
Identities = 118/296 (39%), Positives = 168/296 (55%), Gaps = 4/296 (1%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K + DF L+ LG G+FG+V L + + YA+ HT E +L
Sbjct: 187 KITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQ 246
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
HPF+ + +FQ+ L +M + GGELF+ +RK F P A+FY AE+ LAL Y
Sbjct: 247 RCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGY 306
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTK 315
LH I+YRD+K EN+LLDK+GHIK+ DFG K D T T CGTP+Y+APEV+
Sbjct: 307 LHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDH 366
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
Y + VDWW GV++YEM+ G PFY + K +E I+ +RFP +A+ L++ L+
Sbjct: 367 DYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTLLTGLL 426
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+D +QRLG + ++ +F V WE K IE PY+P +Q+ + DTS +D
Sbjct: 427 VKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQS-ETDTSYFD 481
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 230 bits (586), Expect = 4e-60
Identities = 114/325 (35%), Positives = 191/325 (58%), Gaps = 8/325 (2%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
SG + DF++++ +G G+FG+V+ VR YAM E+ ER++
Sbjct: 126 SGVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDI 185
Query: 197 LSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 256
L+ + HPFI+++ +FQ +L++++D+I GG LF L F +A+ Y AE+ A+
Sbjct: 186 LTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAV 245
Query: 257 EYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT--YTLCGTPDYIAPEVVST 314
+LH KGI++RDLKPENIL+D +GH+ LTDFG AK + T ++CGT +Y+APE+V
Sbjct: 246 SHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRG 305
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKL 374
K ++K+ DWWS G+L+YEML G PF S K + I+ ++ P F ++A ++ L
Sbjct: 306 KGHDKAADWWSVGILLYEMLTGKPPFLGSKG-KIQQKIVKDKIKLPQFLSNEAHAILKGL 364
Query: 375 ITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYP 434
+ ++ +RLG+ +G+E++K H WF + W+KL + + ++P + +G+ + +D+
Sbjct: 365 LQKEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEV-SGRQCIANFDKCW 423
Query: 435 EE----EVNYGIQGEDPYHSIFTNF 455
+ + DP + FTNF
Sbjct: 424 TDMSVLDSPASSPSSDPKANPFTNF 448
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 229 bits (585), Expect = 5e-60
Identities = 126/298 (42%), Positives = 177/298 (59%), Gaps = 8/298 (2%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
Y DF++LR LG G+FG+V+ V+ R YAM HT ERN+L
Sbjct: 407 YGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVT 466
Query: 200 V---SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 256
S PFI+ + +FQ L+++ DY+ GGELF L+K RF AKFY AE+ LAL
Sbjct: 467 TASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLAL 526
Query: 257 EYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY-VPDVTYTLCGTPDYIAPEVVSTK 315
E+LH I+YRDLKPENILLD NG+I L DFG +K + D T T CGT +Y+APE++ +
Sbjct: 527 EHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDE 586
Query: 316 P-YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP-PFFHSDAQDLISK 373
Y K VD+WS GVLI+EM G++PF+ N K Y+ I V+FP + + +
Sbjct: 587 TGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKG 646
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
L+ R+ RLG + +G E ++ HP+F+++ WE L K I P++P + + DTS +D
Sbjct: 647 LLNRNPKHRLGAIDDGRE-LRAHPFFADIDWEALKQKKIPPPFKPHL-VSETDTSNFD 702
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 229 bits (585), Expect = 5e-60
Identities = 117/299 (39%), Positives = 176/299 (58%), Gaps = 8/299 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K L +F+ L+ LG G+FG+V L R + YA+ HT E +L
Sbjct: 179 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLK 238
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
+HPF+I + +FQ + +L +M Y+ GGELF L + F +FY AE+ AL Y
Sbjct: 239 STNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGY 298
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY-----TLCGTPDYIAPEVVS 313
LHS+GIIYRDLK EN+LLDK+GHIK+ DFG K D+TY T CGTP+Y+APEV+
Sbjct: 299 LHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGTPEYLAPEVLD 356
Query: 314 TKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISK 373
Y ++VDWW GV++YEM+ G PFY+ + + IL V+FP +A++L++
Sbjct: 357 DNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAG 416
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
L+ +D +RLG ++ ++++ HP+F+ + W L+ K I P++P + DT +D+
Sbjct: 417 LLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQV-TSDTDTRYFDK 474
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 228 bits (581), Expect = 1e-59
Identities = 114/293 (38%), Positives = 177/293 (59%), Gaps = 5/293 (1%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF ++ LG GSFG+V L + YA+ E T E+ +L++ P
Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408
Query: 204 -FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
F++++ FQ +LF +M+Y+ GG+L +++ +F PVA FYAAE+ L +LH+K
Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAK--YVPD-VTYTLCGTPDYIAPEVVSTKPYNK 319
GI+YRDLK +N+LLD +GH+K+ DFG K V D T T CGTPDYIAPE++ +PY K
Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGK 528
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
SVDWW++GVL+YEML G PF + + + I + V +P +A++ +T+
Sbjct: 529 SVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQP 588
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
++RLG +G EDV+ HP+F + WEK+ + ++ P++P I+ + D S +D+
Sbjct: 589 NKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIK-HRKDVSNFDK 640
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 228 bits (580), Expect = 2e-59
Identities = 114/298 (38%), Positives = 179/298 (59%), Gaps = 6/298 (2%)
Query: 138 GKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNML 197
GK +L DF ++ LG GSFG+V L YA+ + T E+ +L
Sbjct: 401 GKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRIL 460
Query: 198 SIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 256
++ + HPF+ + FQ +LF +M+Y+ GG+L ++K++RF A FYAAEV LAL
Sbjct: 461 ALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLAL 520
Query: 257 EYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVS 313
++LH+ G+IYRDLK +NILLD+ GH KL DFG K +T T CGTPDYIAPE++
Sbjct: 521 QFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILK 580
Query: 314 TKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISK 373
+ Y SVDWW+ GVL+YEM+AG PF N + +++I++ V +P + +A ++
Sbjct: 581 EQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKG 640
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+T++ QRLG +++ HP+F+++ W++L +NI+ P+ P ++ D + +D
Sbjct: 641 FLTKNPEQRLG-CTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMK-NPRDANNFD 696
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 227 bits (579), Expect = 2e-59
Identities = 128/319 (40%), Positives = 176/319 (55%), Gaps = 11/319 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
F++LR LG GSFG+V LVR G YAM TN ER +L+ V
Sbjct: 199 FELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTN-ERKILADVG 257
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
H FI+R+ FQ +L++I+D++ GG+LF+ L K F KFY AE+ LA+ +LH+
Sbjct: 258 HAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHT 317
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNK 319
GIIYRDLKPENILLD++GHI LTDFG +K D TY+ CGT +Y+APE+V+ K ++
Sbjct: 318 LGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIVNRKGHDF 377
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+ DWWSFGVL+YEML G PF+ +T IL + + P +AQ L+ L R+
Sbjct: 378 AADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSPEAQSLLRALFKRNP 437
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG---DTSQYDRYPEE 436
RLG G D+K H +F+ + W +L K + P+ P + D + P +
Sbjct: 438 QNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAVSRDDAFYFDVEYTSKSPRD 497
Query: 437 EVNYGIQGEDPYHSIFTNF 455
I H IF F
Sbjct: 498 SPGGPISAS--AHEIFRGF 514
Score = 105 bits (262), Expect = 1e-22
Identities = 59/207 (28%), Positives = 103/207 (49%), Gaps = 10/207 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXX---XXXXXXXXXXXXEHTNDERNMLSIV 200
++ +L+ LG G+F L + + YA+ + + ML
Sbjct: 567 EYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYG 626
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
+HP I+ ++ ++D+ +++M+ ++GGEL + + A + A+ YLH
Sbjct: 627 NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLH 686
Query: 261 SKGIIYRDLKPENILLDKNGH----IKLTDFGFAKYV---PDVTYTLCGTPDYIAPEVVS 313
G+++RDLKP N++ +KL D GFAK + + T C T +++APEV+
Sbjct: 687 EHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLK 746
Query: 314 TKPYNKSVDWWSFGVLIYEMLAGYTPF 340
+ Y+ + D WS GVL+Y ML+G TPF
Sbjct: 747 RQGYDLACDIWSLGVLLYIMLSGRTPF 773
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 226 bits (576), Expect = 5e-59
Identities = 118/321 (36%), Positives = 183/321 (56%), Gaps = 12/321 (3%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
+ L DF L LG G+FG+V L + YA+ E T E+ +
Sbjct: 677 RIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFL 736
Query: 199 IVS---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+ + HPF++ + FQ +++ +MD++ GG+L +++ Q F A+FYAAEVCLA
Sbjct: 737 VANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQ-FSRRRAQFYAAEVCLA 795
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVV 312
L+Y H GIIYRDLK +NILL +GH+K+ D+G K + + T T CGTP+++APE++
Sbjct: 796 LKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEIL 855
Query: 313 STKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLIS 372
+ Y +SVDWW+FGVLIY+ML G +PF + + ++ IL+ +P D+ ++
Sbjct: 856 LEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSILQ 915
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
+L+TRD +RLG+ N +EDV HP+FS + W+ + K + PY P + + DT +D
Sbjct: 916 QLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNS-PTDTKYFD- 973
Query: 433 YPEEEVNYGIQGEDPYHSIFT 453
EE + P +SI T
Sbjct: 974 ---EEFTRELPVLTPVNSILT 991
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 226 bits (575), Expect = 7e-59
Identities = 118/296 (39%), Positives = 171/296 (56%), Gaps = 6/296 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF L LG GSFG+V L YA+ E T E+ +L++
Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398
Query: 202 HP-FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
P F+ ++ FQ +L+ +M+Y+ GG+L +++ RF P A FYAAE+ + L +L
Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPY 317
SKGIIYRDLK +N++LD GHIK+ DFG K + T T CGTPDYIAPE+++ +PY
Sbjct: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPY 518
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
KSVDWW+FGVL+YEMLAG PF + + +++I+ V +P +A + L+T+
Sbjct: 519 GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTK 578
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRY 433
+RLG G D+K H +F + WEKL K I+ PY+P +A + +DR+
Sbjct: 579 HPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKP--KACGRNAENFDRF 632
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 226 bits (575), Expect = 7e-59
Identities = 118/296 (39%), Positives = 171/296 (56%), Gaps = 6/296 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF L LG GSFG+V L YA+ E T E+ +L++
Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398
Query: 202 HP-FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
P F+ ++ FQ +L+ +M+Y+ GG+L +++ RF P A FYAAE+ + L +L
Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPY 317
SKGIIYRDLK +N++LD GHIK+ DFG K + T T CGTPDYIAPE+++ +PY
Sbjct: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPY 518
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
KSVDWW+FGVL+YEMLAG PF + + +++I+ V +P +A + L+T+
Sbjct: 519 GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTK 578
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRY 433
+RLG G D+K H +F + WEKL K I+ PY+P +A + +DR+
Sbjct: 579 HPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKP--KACGRNAENFDRF 632
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 224 bits (570), Expect = 3e-58
Identities = 115/300 (38%), Positives = 176/300 (58%), Gaps = 7/300 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
+ L +F ++ LG GSFG+V L YA+ + T E+ +L+
Sbjct: 402 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILA 461
Query: 199 IV-SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 257
+ HP++ +++ FQ +LF +M+Y+ GG+L +++S++F P ++FYAAEV AL
Sbjct: 462 LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALM 521
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVST 314
+LH G+IYRDLK +NILLD GH KL DFG K T T CGTPDYIAPE++
Sbjct: 522 FLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQE 581
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKL 374
Y SVDWW+ GVL+YEM+AG PF N +E+IL+ V +P + +A ++
Sbjct: 582 LEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAF 641
Query: 375 ITRDLSQRLGNL--QNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
+T++ +RLG + QNG + +K HP+F E+ W L K I+ P++P I+ + D + +D+
Sbjct: 642 MTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKT-KRDVNNFDQ 700
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 223 bits (569), Expect = 4e-58
Identities = 114/296 (38%), Positives = 176/296 (58%), Gaps = 6/296 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF L LG GSFG+V L YA+ E T E+ +L+++
Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395
Query: 202 HP-FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
P F+ ++ FQ +L+ +M+Y+ GG+L +++ +F P A FYAAE+ + L +LH
Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLH 455
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAK-YVPD--VTYTLCGTPDYIAPEVVSTKPY 317
+GIIYRDLK +N++LD GHIK+ DFG K ++ D T T CGTPDYIAPE+++ +PY
Sbjct: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPY 515
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
KSVDWW++GVL+YEMLAG PF + + +++I+ V +P +A + L+T+
Sbjct: 516 GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTK 575
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRY 433
++RLG G DV+ H +F + WEKL + I+ P++P + G+G +D++
Sbjct: 576 HPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKV-CGKG-AENFDKF 629
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 223 bits (568), Expect = 5e-58
Identities = 122/308 (39%), Positives = 175/308 (56%), Gaps = 8/308 (2%)
Query: 135 VTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXX-EHTNDE 193
V SGK DFQ L LG GS+G+V LV+ + GR +A E T +E
Sbjct: 81 VPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNE 140
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
R +L V HPFI R++ FQD +L++I+ Y GGELFS L + + P V FY AE+
Sbjct: 141 RQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELT 200
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT--YTLCGTPDYIAPEV 311
LAL +LH GI+YRDLKPEN LLD GHI LTDFG +K + + GT +Y APE+
Sbjct: 201 LALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFVGTEEYCAPEI 260
Query: 312 VSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
+ +PY+ +VDWWS G+LI+++L G PF +N + E I A P + SDA+D+I
Sbjct: 261 LLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARDII 320
Query: 372 SKLITRDLSQRLG--NLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPI---QAGQGD 426
+K + ++ QRLG + G + +K H + + W KL + + P P I +A +
Sbjct: 321 NKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENF 380
Query: 427 TSQYDRYP 434
+ ++ + P
Sbjct: 381 SVEFTKLP 388
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 223 bits (567), Expect = 6e-58
Identities = 118/317 (37%), Positives = 181/317 (56%), Gaps = 12/317 (3%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF ++R +G GS+ +V LVR N + YAM + E+++ S
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 202 -HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
+PF++ + FQ + +LF++++Y+ GG+L +++ ++ P A+FYAAE+C+AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPY 317
+GIIYRDLK +N+LLD +GHIKLTD+G K D T T CGTP+YIAPE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 318 NKSVDWWSFGVLIYEMLAGYTPF------YDSNTIK-TYENILNAPVRFPPFFHSDAQDL 370
SVDWW+ GVL++EM+AG +PF D NT ++ IL P+R P F A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 371 ISKLITRDLSQRLG-NLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQ 429
+ + +D +RLG Q G D+K+H +F + W+ L K P++P I G +
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 430 YDRYPEEEVNYGIQGED 446
++ E V ED
Sbjct: 549 DTQFTSEPVQLTPDDED 565
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 223 bits (567), Expect = 6e-58
Identities = 118/317 (37%), Positives = 181/317 (56%), Gaps = 12/317 (3%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF ++R +G GS+ +V LVR N + YAM + E+++ S
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 202 -HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
+PF++ + FQ + +LF++++Y+ GG+L +++ ++ P A+FYAAE+C+AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPY 317
+GIIYRDLK +N+LLD +GHIKLTD+G K D T T CGTP+YIAPE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 318 NKSVDWWSFGVLIYEMLAGYTPF------YDSNTIK-TYENILNAPVRFPPFFHSDAQDL 370
SVDWW+ GVL++EM+AG +PF D NT ++ IL P+R P F A +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 371 ISKLITRDLSQRLG-NLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQ 429
+ + +D +RLG Q G D+K+H +F + W+ L K P++P I G +
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 430 YDRYPEEEVNYGIQGED 446
++ E V ED
Sbjct: 549 DTQFTSEPVQLTPDDED 565
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 221 bits (564), Expect = 1e-57
Identities = 115/301 (38%), Positives = 170/301 (56%), Gaps = 9/301 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K + DF L+ LG G+FG+V L + + YA+ HT E +L
Sbjct: 187 KITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQ 246
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKS-----QRFPNPVAKFYAAEVC 253
HPF+ + +FQ + +L +M++ GG+L+ L + + F P A+FY +E+
Sbjct: 247 RCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGSEIV 306
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPE 310
LAL YLH+ I+YRDLK EN+LLDK+GHIK+ DFG K D T T CGTP+Y+APE
Sbjct: 307 LALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPE 366
Query: 311 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDL 370
V+ Y + VDWW GV++YEM+ G PFY + K +E I+ +RFP +A+ L
Sbjct: 367 VLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTL 426
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQY 430
++ L+ +D +QRLG + ++ +F V WE K IE PY+P +Q+ + DTS +
Sbjct: 427 LTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQS-ETDTSYF 485
Query: 431 D 431
D
Sbjct: 486 D 486
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 221 bits (562), Expect = 2e-57
Identities = 122/323 (37%), Positives = 186/323 (56%), Gaps = 14/323 (4%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRS---NHNGRFYAMXXXXXXXXXXXXXX-EHTNDER 194
K ++ +F++L+ LGTG++G+V LVR + G+ YAM EHT ER
Sbjct: 27 KVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86
Query: 195 NMLSIVSH-PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
++L +V PF++ + FQ +L +I+DY+ GGE+F+ L + Q F + Y E+
Sbjct: 87 SVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIV 146
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV----PDVTYTLCGTPDYIAP 309
LALE+LH GIIYRDLK EN+LLD GHI LTDFG +K + T++ CGT +Y+AP
Sbjct: 147 LALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAP 206
Query: 310 EVVSTKP-YNKSVDWWSFGVLIYEMLAGYTPFY---DSNT-IKTYENILNAPVRFPPFFH 364
E++ +K + K+VDWWS G+L++E+L G +PF + NT + IL FPP
Sbjct: 207 EIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIG 266
Query: 365 SDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQ 424
AQDL+ +L+ +D +RLG G+++V+NHP+F + W L + I P+ P I++
Sbjct: 267 PVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSEL 326
Query: 425 GDTSQYDRYPEEEVNYGIQGEDP 447
+ + + E Y G P
Sbjct: 327 DVGNFAEEFTRLEPVYSPPGSPP 349
Score = 103 bits (256), Expect = 7e-22
Identities = 61/201 (30%), Positives = 101/201 (49%), Gaps = 19/201 (9%)
Query: 151 LGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI---VSHPFIIR 207
LG GSF R +G+ +A+ N +R + ++ SHP ++
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRL--------EANTQREVAALRLCQSHPNVVN 468
Query: 208 MWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK-GIIY 266
+ D +++++ + GGEL +RK + F A + A+ ++H + G+++
Sbjct: 469 LHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVH 528
Query: 267 RDLKPENILLDKN---GHIKLTDFGFAKYVPDVT----YTLCGTPDYIAPEVVSTKPYNK 319
RDLKPENIL + +K+ DFGFA+ P T C T Y APE+++ + Y++
Sbjct: 529 RDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDE 588
Query: 320 SVDWWSFGVLIYEMLAGYTPF 340
S D WS GV++Y ML+G PF
Sbjct: 589 SCDLWSLGVILYMMLSGQVPF 609
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 221 bits (562), Expect = 2e-57
Identities = 117/328 (35%), Positives = 186/328 (56%), Gaps = 18/328 (5%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF L LG GSFG+V L +A+ E T E+ +L++ P
Sbjct: 412 DFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKP 471
Query: 204 -FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
F++ + FQ +L+ +M+++ GG+L +++ +F PVA FYAAE+ + L +LHSK
Sbjct: 472 SFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSK 531
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
GIIYRDLK +N++L+++GHIK+TDFG K + T T CGTPDYIAPE++ +PY K
Sbjct: 532 GIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGK 591
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
SVDWW++GVL++EMLAG PF + + + I V +P +A L L+ ++
Sbjct: 592 SVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNP 651
Query: 380 SQRL---GNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRY--- 433
S+RL G+ ++ S D+K HP+F + W K+ + I+ P++P ++ + T +D
Sbjct: 652 SKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDR-STENFDHSFLK 710
Query: 434 -------PEEEVNYGIQGEDPYHSIFTN 454
P+ EV ++G++ + F N
Sbjct: 711 LPTKMTPPDWEVLENLKGDEFSNFSFVN 738
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 220 bits (561), Expect = 3e-57
Identities = 116/309 (37%), Positives = 180/309 (57%), Gaps = 11/309 (3%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R + L DF L LG G+FG+V L N +FYA+ E E
Sbjct: 561 REKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTE 620
Query: 194 RNMLSIVS---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA 250
+++ + + HPF++ ++ +FQ S +++ +M+YI GG+L +++ Q+F A+FY A
Sbjct: 621 KHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQR-QQFSVKRARFYGA 679
Query: 251 EVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYI 307
EVCLAL+Y H GI YRDLK +NILL +GHI++ D+G K + + T T CGTP+++
Sbjct: 680 EVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTSTFCGTPEFM 739
Query: 308 APEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDA 367
APE++ + Y+K VDWW+FGVL+Y+ML G +PF + + ++ IL+ FP +DA
Sbjct: 740 APEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPADA 799
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDT 427
L+ L+TRD +QRLG+ + +V HP+F+ +VW+ L K E Y+P I D
Sbjct: 800 VSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKPLI----NDP 855
Query: 428 SQYDRYPEE 436
+ + EE
Sbjct: 856 RDLNNFDEE 864
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 219 bits (558), Expect = 7e-57
Identities = 119/332 (35%), Positives = 181/332 (53%), Gaps = 14/332 (4%)
Query: 129 STLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXE 188
+T ++ S L DF +LR +G GS+ +V LVR R YAM +
Sbjct: 229 NTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDID 288
Query: 189 HTNDERNMLSIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKF 247
E+++ S HPF++ + FQ +LF +++Y+ GG+L +++ ++ P A+F
Sbjct: 289 WVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARF 348
Query: 248 YAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTP 304
Y+AE+ LAL YLH +GIIYRDLK +N+LLD GHIKLTD+G K D T T CGTP
Sbjct: 349 YSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTP 408
Query: 305 DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF--------YDSNTIK-TYENILNA 355
+YIAPE++ + Y SVDWW+ GVL++EM+AG +PF D NT ++ IL
Sbjct: 409 NYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEK 468
Query: 356 PVRFPPFFHSDAQDLISKLITRDLSQRLG-NLQNGSEDVKNHPWFSEVVWEKLLCKNIET 414
+R P A ++ + +D +RLG + Q G D++ HP+F V W+ + K +
Sbjct: 469 QIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVP 528
Query: 415 PYEPPIQAGQGDTSQYDRYPEEEVNYGIQGED 446
P++P I G + ++ E V +D
Sbjct: 529 PFKPNISGEFGLDNFDSQFTNEPVQLTPDDDD 560
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 219 bits (558), Expect = 7e-57
Identities = 114/298 (38%), Positives = 178/298 (59%), Gaps = 6/298 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K+AL F +L+ LG GSFG+V LV FYAM E T ER +L
Sbjct: 232 KFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLI 291
Query: 199 IVSH-PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 257
+ S PF+ +++ +FQ ++ LF +M+Y+ GG+L +++ ++F +FYA E+ +AL+
Sbjct: 292 LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQ 351
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD----VTYTLCGTPDYIAPEVVS 313
+LH+ IIYRDLK +N+LLD +GHIKL DFG AK + + T CGTPDYI+PE++
Sbjct: 352 FLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIK 411
Query: 314 TKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISK 373
+ YN++VD+WSFGVL+YEML G +PF+ + +++ILN FP +A +S
Sbjct: 412 GQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLSA 471
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
L R+ + RLG + ++ H +F V W++ + + P++P I++ D S +D
Sbjct: 472 LFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKS-NSDASNFD 528
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 219 bits (558), Expect = 7e-57
Identities = 114/298 (38%), Positives = 178/298 (59%), Gaps = 6/298 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K+AL F +L+ LG GSFG+V LV FYAM E T ER +L
Sbjct: 369 KFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLI 428
Query: 199 IVSH-PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 257
+ S PF+ +++ +FQ ++ LF +M+Y+ GG+L +++ ++F +FYA E+ +AL+
Sbjct: 429 LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQ 488
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD----VTYTLCGTPDYIAPEVVS 313
+LH+ IIYRDLK +N+LLD +GHIKL DFG AK + + T CGTPDYI+PE++
Sbjct: 489 FLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIK 548
Query: 314 TKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISK 373
+ YN++VD+WSFGVL+YEML G +PF+ + +++ILN FP +A +S
Sbjct: 549 GQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLSA 608
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
L R+ + RLG + ++ H +F V W++ + + P++P I++ D S +D
Sbjct: 609 LFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKS-NSDASNFD 665
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 219 bits (558), Expect = 7e-57
Identities = 114/299 (38%), Positives = 177/299 (59%), Gaps = 7/299 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGR--FYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
L D +++ TLG G FGRV LV+++H R +A+ EH ER+++
Sbjct: 454 LTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLS 513
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
PFI R++ TF+D + ++M+++ GGE++++LR F + A+F V A EYL
Sbjct: 514 SRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYL 573
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV--PDVTYTLCGTPDYIAPEVVSTKPY 317
H++GIIYRDLKPEN++LD+ G++K+ DFGFAK + T+T CGTP+Y+APE++ K +
Sbjct: 574 HARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGH 633
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNA--PVRFPPFFHSDAQDLISKLI 375
+++VD+W+ G+LI+E+L G PF + ++TY IL + FP A LI +L
Sbjct: 634 DRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLC 693
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYP 434
S+RLG G +D+K H WF W+ L + + P+ PI A D +DR+P
Sbjct: 694 RDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPI-AHPTDVRYFDRFP 751
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 218 bits (556), Expect = 1e-56
Identities = 112/292 (38%), Positives = 168/292 (57%), Gaps = 4/292 (1%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF L+ LG G+FG+V L R + + YA+ HT E +L HP
Sbjct: 179 DFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACVHP 238
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F+ + +FQ + +M++ GGELF+ L++ + F +FY +E+ LAL YLH +
Sbjct: 239 FLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRN 298
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPYNKS 320
I+YRD+K EN+LLD++GHIK+TDFG K D T T CGTP+Y+APEV+ Y++S
Sbjct: 299 IVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRS 358
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VDWW GV++YEM+ G PF K +E I ++FP +A L+S L+ R +
Sbjct: 359 VDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVTLLSGLLERVPA 418
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
+RLG + + +V +F +V WE L K +E P++P + + + DTS +DR
Sbjct: 419 KRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMS-ETDTSFFDR 469
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 218 bits (556), Expect = 1e-56
Identities = 112/292 (38%), Positives = 168/292 (57%), Gaps = 4/292 (1%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF L+ LG G+FG+V L R + + YA+ HT E +L HP
Sbjct: 179 DFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACVHP 238
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F+ + +FQ + +M++ GGELF+ L++ + F +FY +E+ LAL YLH +
Sbjct: 239 FLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRN 298
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPYNKS 320
I+YRD+K EN+LLD++GHIK+TDFG K D T T CGTP+Y+APEV+ Y++S
Sbjct: 299 IVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRS 358
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VDWW GV++YEM+ G PF K +E I ++FP +A L+S L+ R +
Sbjct: 359 VDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVTLLSGLLERVPA 418
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
+RLG + + +V +F +V WE L K +E P++P + + + DTS +DR
Sbjct: 419 KRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMS-ETDTSFFDR 469
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 216 bits (551), Expect = 4e-56
Identities = 123/358 (34%), Positives = 189/358 (52%), Gaps = 61/358 (17%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ K ++ DF++L +G G+FG V L R +G YAM EH E
Sbjct: 83 RLKRNKISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMVMRGQVEHVRAE 142
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
RN+L+ V +I++++ +FQD + L++IM+Y+ GG++ +LL + VA+FY A+
Sbjct: 143 RNLLAEVESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLREDVARFYIAQSV 202
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV-------------------- 293
LA+E +H I+RD+KP+N+LLDK+GH+KL+DFG K +
Sbjct: 203 LAIESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQENRATDDETMS 262
Query: 294 ---------PD-----------------------VTYTLCGTPDYIAPEVVSTKPYNKSV 321
PD + ++ GTPDYIAPEV+ K Y
Sbjct: 263 EPMDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDYIAPEVLLKKGYGMEC 322
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN--APVRFP--PFFHSDAQDLISKLITR 377
DWWS G ++YEML GY PFY + I T I++ ++FP F S+A+DLI +L+
Sbjct: 323 DWWSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPEDAKFSSEAKDLICRLLC- 381
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPE 435
++ RLG G++ +K+HPWF +VVWEKL +E Y+P + + DT + ++ E
Sbjct: 382 NVDHRLGT-GGGAQQIKDHPWFKDVVWEKLY--EMEAAYKPEVN-DELDTQNFMKFDE 435
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 216 bits (550), Expect = 6e-56
Identities = 121/317 (38%), Positives = 187/317 (58%), Gaps = 15/317 (4%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVR--SNHN-GRFYAMXXXXXXXXXXXX-XXEHTNDER 194
K + +F++L+ LGTG++G+V LVR S H+ G+ YAM EHT ER
Sbjct: 43 KVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTER 102
Query: 195 NMLS-IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
+L I PF++ + FQ +L +I+DYI GGELF+ L + +RF + Y E+
Sbjct: 103 QVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIV 162
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK-YVPDVT---YTLCGTPDYIAP 309
LALE+LH GIIYRD+K ENILLD NGH+ LTDFG +K +V D T Y+ CGT +Y+AP
Sbjct: 163 LALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAP 222
Query: 310 EVV--STKPYNKSVDWWSFGVLIYEMLAGYTPF----YDSNTIKTYENILNAPVRFPPFF 363
++V ++K+VDWWS GVL+YE+L G +PF ++ + IL + +P
Sbjct: 223 DIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEM 282
Query: 364 HSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAG 423
+ A+DLI +L+ +D +RLG ++++K H +F ++ W+ L K + P++P I+
Sbjct: 283 SALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDE 342
Query: 424 QGDTSQYDRYPEEEVNY 440
++ + + E + Y
Sbjct: 343 LDVSNFAEEFTEMDPTY 359
Score = 115 bits (289), Expect = 1e-25
Identities = 67/199 (33%), Positives = 105/199 (52%), Gaps = 17/199 (8%)
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HP I+++ F D F++M+ + GGELF LRK + F A + ++ AL ++H
Sbjct: 478 HPNIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHD 537
Query: 262 KGIIYRDLKPENILL---DKNGHIKLTDFGFAKYVPDVTYTL---CGTPDYIAPEVVSTK 315
G+++RDLKPEN+L + N IK+ DFGFA+ P L C T PE+++
Sbjct: 538 LGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQN 597
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYD-------SNTIKTYENILNAPVRFP----PFFH 364
Y++S D WS GV++Y ML+G PF ++ ++ + I F
Sbjct: 598 GYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVS 657
Query: 365 SDAQDLISKLITRDLSQRL 383
+A+DLI L+T D ++RL
Sbjct: 658 QEAKDLIQGLLTVDPNKRL 676
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 215 bits (547), Expect = 1e-55
Identities = 112/301 (37%), Positives = 173/301 (57%), Gaps = 14/301 (4%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
T +Y+L DF+++R +G GS+ +V +V R YAM + E++
Sbjct: 252 TQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKH 311
Query: 196 MLSIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCL 254
+ S HPF++ + FQ +LF +++++ GG+L +++ +R P A+FYAAE+ L
Sbjct: 312 VFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISL 371
Query: 255 ALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEV 311
AL +LH KGIIYRDLK +N+LLD GHIKLTD+G K D T T CGTP+YIAPE+
Sbjct: 372 ALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEI 431
Query: 312 VSTKPYNKSVDWWSFGVLIYEMLAGYTPF--------YDSNTIK-TYENILNAPVRFPPF 362
+ + Y SVDWW+ GVL+YEMLAG +PF D NT ++ IL +R P
Sbjct: 432 LRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRS 491
Query: 363 FHSDAQDLISKLITRDLSQRLG-NLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQ 421
A ++ + ++ + RLG + ++ D+ +HP+F + WE L K + P++P +
Sbjct: 492 LSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLD 551
Query: 422 A 422
+
Sbjct: 552 S 552
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 214 bits (545), Expect = 2e-55
Identities = 110/300 (36%), Positives = 169/300 (55%), Gaps = 4/300 (1%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF ++ +G GSFG+V L YA+ E +E+ +L++ P
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429
Query: 204 -FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
F++ M FQ +LF +M+Y +GG+L +++ RF VA FYA EV +AL +LH +
Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPYNK 319
IIYRDLK +NILLD GH+KL DFG +K T T CGTP+Y+APE+VS PY+
Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSI 549
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+ DWWSFGVL++E +AG PF + + NI + FP F +A D+I+ +T+
Sbjct: 550 AADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKP 609
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEVN 439
+ RLG + +++ HP+F V W+K +E P +P I+ + ++ D + +E+ +
Sbjct: 610 NNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTD 669
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 213 bits (543), Expect = 4e-55
Identities = 110/296 (37%), Positives = 174/296 (58%), Gaps = 8/296 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF+ L LG G FG+V L +G +A+ E E+ +L+ V+
Sbjct: 612 LEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVT 671
Query: 202 ---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
HPF++ ++G FQ + + +M+Y GG+L + S F P A FY+A V L L++
Sbjct: 672 SAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFYSACVVLGLQF 730
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTK 315
LH I+YRDLK +N+LLD G++K+ DFG K D T T CGTP+++APEV++
Sbjct: 731 LHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDT 790
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
Y ++VDWW GVL+YEML G +PF + + +++I+N VR+P F ++A ++ +L+
Sbjct: 791 SYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLL 850
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
R+ +RLG+ + +EDVK P+F + WE LL + + P+ P + +G+ D S +D
Sbjct: 851 RRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTL-SGRTDVSNFD 905
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 213 bits (543), Expect = 4e-55
Identities = 110/296 (37%), Positives = 174/296 (58%), Gaps = 8/296 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF+ L LG G FG+V L +G +A+ E E+ +L+ V+
Sbjct: 612 LEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVT 671
Query: 202 ---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
HPF++ ++G FQ + + +M+Y GG+L + S F P A FY+A V L L++
Sbjct: 672 SAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFYSACVVLGLQF 730
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTK 315
LH I+YRDLK +N+LLD G++K+ DFG K D T T CGTP+++APEV++
Sbjct: 731 LHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDT 790
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
Y ++VDWW GVL+YEML G +PF + + +++I+N VR+P F ++A ++ +L+
Sbjct: 791 SYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLL 850
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
R+ +RLG+ + +EDVK P+F + WE LL + + P+ P + +G+ D S +D
Sbjct: 851 RRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTL-SGRTDVSNFD 905
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 213 bits (543), Expect = 4e-55
Identities = 121/355 (34%), Positives = 182/355 (51%), Gaps = 57/355 (16%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ K + DF++L +G G+FG V L R YAM EH E
Sbjct: 91 RLQRRKIGIDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKKTEMLSRGQVEHVRSE 150
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
RN+L+ V +I++++ +FQDS+ L++IM+Y+ GG++ +LL + VA+FY AE
Sbjct: 151 RNLLAEVDSRYIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMREDILSEDVARFYIAESI 210
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD------------------ 295
LA+ +H ++RD+KP+N++LDK+GH+KL+DFG K + D
Sbjct: 211 LAIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLCKPLDDKYSSLLLEDDEMLSQDSE 270
Query: 296 -----------------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSF 326
+ Y+ GT DY+APEV+ K Y DWWS
Sbjct: 271 NQSGKSDADKAPWQMPKEQLLQWKRNRRALAYSTVGTLDYMAPEVLLKKGYGMECDWWSL 330
Query: 327 GVLIYEMLAGYTPFYDSNTIKTYENILNAPV--RFP--PFFHSDAQDLISKLITRDLSQR 382
G ++YEML GY PF + T I+N V +FP P +A+DLI +L+ D+ R
Sbjct: 331 GAILYEMLVGYPPFCSDDPRITCRKIINWRVCLKFPEEPKISDEARDLICRLLC-DVDSR 389
Query: 383 LGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEE 437
LG G E++K+HPWF W+KL ++E Y PI G+ DT ++++PE E
Sbjct: 390 LGT--RGVEEIKSHPWFKGTPWDKLY--DMEAAYR-PIVDGELDTQNFEKFPEVE 439
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 212 bits (540), Expect = 8e-55
Identities = 108/290 (37%), Positives = 165/290 (56%), Gaps = 9/290 (3%)
Query: 138 GKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNML 197
G+ + DF L LG GSFG+V L + YA+ + T E+ +L
Sbjct: 344 GRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVL 403
Query: 198 SIVSHP------FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 251
++ F+ ++ TFQ +L+ +M+Y+ GG+L +++ +F P A FYAAE
Sbjct: 404 ALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAE 463
Query: 252 VCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIA 308
+ + L +LH++GIIYRDLK +N++LD GHIK+TDFG K + T T CGTPDYIA
Sbjct: 464 IAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIA 523
Query: 309 PEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQ 368
PE+++ +PY KSVDWWSFGVL+YEMLAG PF + + ++ I+ V +P +A
Sbjct: 524 PEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAV 583
Query: 369 DLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP 418
+ +T+ +RLG+ +G ++ H +F + WE+L I P+ P
Sbjct: 584 AICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRP 633
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 212 bits (539), Expect = 1e-54
Identities = 113/300 (37%), Positives = 175/300 (57%), Gaps = 9/300 (3%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
S K + +F + LG GSFG+V L G ++A+ E T E+ +
Sbjct: 341 SSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRV 400
Query: 197 LSIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
L++ + +PF+ + TFQ LF +M+++ GG+L ++ RF A FYAAE+
Sbjct: 401 LTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCG 460
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVV 312
L++LHSKGIIYRDLK +N+LLD++GHIK+ DFG K + T CGTPDYIAPE++
Sbjct: 461 LQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEIL 520
Query: 313 STKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLIS 372
Y SVDWWSFGVL+YEML G +PF+ + + +E+I +P + +++D++
Sbjct: 521 QGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILE 580
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
KL R+ ++RLG N +K HP+F + W L + +E P+ P +++ + D S +D+
Sbjct: 581 KLFEREPTKRLGVTGN----IKIHPFFKTINWTLLEKRRLEPPFRPKVKSPR-DYSNFDQ 635
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 211 bits (538), Expect = 1e-54
Identities = 111/319 (34%), Positives = 180/319 (55%), Gaps = 8/319 (2%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
+G ++ +F++L LG G FG+V L + N ++YA+ E E+ +
Sbjct: 255 AGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRI 314
Query: 197 LSIVS---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
+ + HPF++ ++ FQ Q + +M+Y GG+L + + F P A FYAA V
Sbjct: 315 FEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIH-TDVFLEPRAVFYAACVV 373
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPE 310
L L+YLH IIYRDLK +N+LLD G++K+ DFG K D T T CGTP+++APE
Sbjct: 374 LGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPE 433
Query: 311 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDL 370
V++ Y ++VDWW GVLI+EML G +PF + + +++I+N VR+P F +A +
Sbjct: 434 VLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAV 493
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQY 430
+ +L+ ++ +RLG+ + +EDVK +F +VW+ LL + ++ P+ P I + D S +
Sbjct: 494 MRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLE-DVSNF 552
Query: 431 DRYPEEEVNYGIQGEDPYH 449
D E ++P H
Sbjct: 553 DEEFTSEKAQLTPPKEPRH 571
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 211 bits (538), Expect = 1e-54
Identities = 111/319 (34%), Positives = 180/319 (55%), Gaps = 8/319 (2%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
+G ++ +F++L LG G FG+V L + N ++YA+ E E+ +
Sbjct: 949 AGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRI 1008
Query: 197 LSIVS---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
+ + HPF++ ++ FQ Q + +M+Y GG+L + + F P A FYAA V
Sbjct: 1009 FEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIH-TDVFLEPRAVFYAACVV 1067
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPE 310
L L+YLH IIYRDLK +N+LLD G++K+ DFG K D T T CGTP+++APE
Sbjct: 1068 LGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPE 1127
Query: 311 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDL 370
V++ Y ++VDWW GVLI+EML G +PF + + +++I+N VR+P F +A +
Sbjct: 1128 VLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAV 1187
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQY 430
+ +L+ ++ +RLG+ + +EDVK +F +VW+ LL + ++ P+ P I + D S +
Sbjct: 1188 MRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLE-DVSNF 1246
Query: 431 DRYPEEEVNYGIQGEDPYH 449
D E ++P H
Sbjct: 1247 DEEFTSEKAQLTPPKEPRH 1265
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 211 bits (536), Expect = 2e-54
Identities = 107/250 (42%), Positives = 152/250 (60%), Gaps = 3/250 (1%)
Query: 136 TSGKYALYDFQILRT-LGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDER 194
T Y + I R LG GSFG V LVR +YA H ++E+
Sbjct: 35 TQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEK 94
Query: 195 NMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCL 254
++L+ PF+I + + + L++I+ + GGELFS R+ ++F A+FYAA+V L
Sbjct: 95 HVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVAL 154
Query: 255 ALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVST 314
ALEY+H ++YRDLKPENILLD+ G+IK+TDFGF K V T TLCGTP+Y+APE+V
Sbjct: 155 ALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQL 214
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPF--YDSNTIKTYENILNAPVRFPPFFHSDAQDLIS 372
+PYNKSVDWW+FG+L+YE +AG +PF ++ + I Y I + P +F S + L+
Sbjct: 215 RPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVE 274
Query: 373 KLITRDLSQR 382
L+ D S+R
Sbjct: 275 SLMQVDTSKR 284
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 210 bits (535), Expect = 3e-54
Identities = 113/300 (37%), Positives = 174/300 (57%), Gaps = 9/300 (3%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
S K + +F + LG GSFG+V L G + A+ E T E+ +
Sbjct: 341 SSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRV 400
Query: 197 LSIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
L++ + +PF+ + TFQ LF +M+++ GG+L ++ RF A FYAAE+
Sbjct: 401 LTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCG 460
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVV 312
L++LHSKGIIYRDLK +N+LLD++GHIK+ DFG K + T CGTPDYIAPE++
Sbjct: 461 LQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEIL 520
Query: 313 STKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLIS 372
Y SVDWWSFGVL+YEML G +PF+ + + +E+I +P + +++D++
Sbjct: 521 QGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILE 580
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
KL R+ ++RLG N +K HP+F + W L + +E P+ P +++ + D S +D+
Sbjct: 581 KLFEREPTKRLGMTGN----IKIHPFFKTINWTLLEKRRLEPPFRPKVKSPR-DYSNFDQ 635
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 210 bits (535), Expect = 3e-54
Identities = 119/316 (37%), Positives = 184/316 (57%), Gaps = 21/316 (6%)
Query: 141 ALYDFQILRTLGTGSFGRVHLVR--SNHN-GRFYAMXXXXXXXXXXXX-XXEHTNDERNM 196
+L DF+I+R LGTG++GRV LVR + H+ G+ YAM EHT ER +
Sbjct: 257 SLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVV 316
Query: 197 LSIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
L + +PF++ + FQ S +L++++D+ GGELF+ L S+ F + Y AEV LA
Sbjct: 317 LEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLA 376
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV----TYTLCGTPDYIAPEV 311
LE LH GIIYRD+K ENILLD GHI L+DFG +K + ++ CGT +Y+APE+
Sbjct: 377 LEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEI 436
Query: 312 VSTKP--YNKSVDWWSFGVLIYEMLAGYTPFYDSN----TIKTYENILNAPVRFPPFFHS 365
+ T P ++ +VDWWS GVL +E+L G +PF S+ + I P F +
Sbjct: 437 IRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSA 496
Query: 366 DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG 425
+A+D + K++ ++ +RLG + ++K HP+F+ + W++L K + PY+P + A +
Sbjct: 497 NARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTA-ED 555
Query: 426 DTSQY-----DRYPEE 436
D + D+ PE+
Sbjct: 556 DVQNFSNEFTDQVPED 571
Score = 73.9 bits (180), Expect = 5e-13
Identities = 46/156 (29%), Positives = 82/156 (52%), Gaps = 20/156 (12%)
Query: 197 LSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 256
L +H I+ GTF++ + +++M+Y+ G EL + +R + + ++ +A+
Sbjct: 672 LDTTNHKNIVSYHGTFREKCETWIVMEYLSGPELTASIRMDEDSCREIF----LQLVMAV 727
Query: 257 EYLHSKGIIYRDLKPENILLD--KNGHIKLTDFG-------FAKYVPDVTYTLCGTPDYI 307
++HSK I+ DLKPENI+ + ++ +KL DFG F + YTL DY
Sbjct: 728 RHIHSKHFIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRYTL----DYA 783
Query: 308 APEVVSTK---PYNKSVDWWSFGVLIYEMLAGYTPF 340
PE+++ Y+ +VD + G +Y ML G+ P+
Sbjct: 784 PPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPY 819
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 210 bits (534), Expect = 4e-54
Identities = 108/299 (36%), Positives = 170/299 (56%), Gaps = 8/299 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
++ L DF+ LG G FG+V L + +A+ + E+ +
Sbjct: 651 QFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFE 710
Query: 199 IVS---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
V+ HPF++ ++ FQ + + +M+Y GG+L + + F P A FYAA V L
Sbjct: 711 TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIH-TDVFSEPRAVFYAACVVLG 769
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVV 312
L+YLH I+YRDLK +N+LLD G +K+ DFG K D T T CGTP+++APEV+
Sbjct: 770 LQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVL 829
Query: 313 STKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLIS 372
+ Y ++VDWW GVLIYEML G +PF + + +++I+N VR+P F ++A ++
Sbjct: 830 TETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMR 889
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+L+ R+ +RLG + +EDVK HP+F + W L+ K ++ P+ P I+ G+ D S +D
Sbjct: 890 RLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIR-GREDVSNFD 947
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 210 bits (534), Expect = 4e-54
Identities = 117/297 (39%), Positives = 174/297 (58%), Gaps = 8/297 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L D Q + TLG G FGRV LVRS + R YA+ H ER +L
Sbjct: 271 LEDLQRVSTLGMGGFGRVELVRSA-SSRTYALKIMNKAHIVETKQESHVVSERRILMQCD 329
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
+ +I+RM+ T++DS++++M+M+ GGE++++LRK RF N + +FY A ALEYLH
Sbjct: 330 NDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYLHR 389
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNK 319
K I+YRDLKPEN+LLD+NG KL DFGFAK + + T+T CGT +Y+APE+V K ++
Sbjct: 390 KNIVYRDLKPENMLLDRNGWPKLVDFGFAKKLKNGGRTWTFCGTAEYVAPEIVLNKGHDL 449
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVR--FPPFFHSDAQDLISKLITR 377
SVD W+ G+ + E+L G PF ++ + TY IL + +P F +A D++ L
Sbjct: 450 SVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAIDMMLSLCKY 509
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYP 434
+ ++RLG G ++++H WF + I P+ P + A DTS +D +P
Sbjct: 510 EPTERLGFGDIG--EIRHHIWFDNFDFVGFRAHRIRPPFIPSV-ANDIDTSNFDTFP 563
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 209 bits (531), Expect = 9e-54
Identities = 120/351 (34%), Positives = 183/351 (51%), Gaps = 53/351 (15%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ K DF++L +G G+FG V +VR + G +AM EH E
Sbjct: 126 RLQRHKMGADDFELLTMIGKGAFGEVRVVREINTGHVFAMKKLKKSEMLRRGQVEHVRAE 185
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
RN+L+ V I++++ +FQD++ L++IM+Y+ GG++ +LL + AKFY AE
Sbjct: 186 RNLLAEVDSNCIVKLYCSFQDNEYLYLIMEYLPGGDMMTLLMRKDTLSEDEAKFYIAESV 245
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV-------PDVT--------- 297
LA+E +H++ I+RD+KP+N+LLD+ GH++L+DFG K + D T
Sbjct: 246 LAIESIHNRNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSVIDGEDFTVGNAGSGGG 305
Query: 298 ---------------------------YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLI 330
Y+ GTPDYIAPEV+ K Y DWWS G ++
Sbjct: 306 SESVSTTPKRSQQEQLEHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 365
Query: 331 YEMLAGYTPFYDSNTIKTYENILN--APVRFP--PFFHSDAQDLISKLITRDLSQRLGNL 386
YEML GY PFY + + T I+N ++FP A+DLI KL+ ++QRLG+
Sbjct: 366 YEMLVGYPPFYADDPMSTCRKIVNWKTHLKFPEESRLSRGARDLIGKLLC-SVNQRLGS- 423
Query: 387 QNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEE 437
G+ +K HPWF V WEK+ +E + P + DT ++++ EE+
Sbjct: 424 -TGASQIKAHPWFEGVQWEKIY--QMEAAFIPEVN-DDLDTQNFEKFDEED 470
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 207 bits (526), Expect = 3e-53
Identities = 106/279 (37%), Positives = 167/279 (58%), Gaps = 4/279 (1%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGR-FYAMXXXXXXXXXXXXXXEHTNDERNMLS-I 199
+ DF+ ++ +G G+FG+VHLVR + +AM + +E ++L I
Sbjct: 4 IQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRI 63
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
PF+ +++ T ++ +IM+Y+ GGELF L+K RF +A+FYAAE+ AL ++
Sbjct: 64 YGCPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFI 123
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
H +GI+YRDLKPENIL+ GHIKL DFGF+ Y + Y + GTP+Y++PE + ++ +
Sbjct: 124 HGRGILYRDLKPENILITSTGHIKLIDFGFSVYESENIYMISGTPEYMSPEKLRSEDDGR 183
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+ D+W GV+IYEML G PFYDS+ Y IL + V FP + A+ LI+ L+ ++
Sbjct: 184 ASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVARCLITGLLDKNR 243
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP 418
+ RLG G ++ HP+F + W ++ + IE P+ P
Sbjct: 244 ATRLGT--KGICEIMGHPFFKGIDWHEVESRRIEPPFIP 280
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 207 bits (526), Expect = 3e-53
Identities = 104/295 (35%), Positives = 169/295 (57%), Gaps = 13/295 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSN---HNGRFYAMXXXXXXXXXXXXXX-EHTNDERNMLSI 199
DF+ L+ +G G +G+V VR G YAM H DER +L
Sbjct: 22 DFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILET 81
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
++ PF+ + FQ +++L+++++++ GGEL++LL + +P A+FY +E+ LA+E+L
Sbjct: 82 INSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEHL 141
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKP 316
H I+YRDLKP+N++L+ GH+ LTDFG KY + T T CGT +Y+APE++
Sbjct: 142 HGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFCGTHEYMAPEMIRKVG 201
Query: 317 YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLIT 376
++ +VD W+ G+L+Y+M G PF ++IL VR PP + +DLI ++I
Sbjct: 202 HDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSASGKDLIKRIIK 261
Query: 377 RDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
RD + R+ D+K H +F E+ W+KL+ + E P++P + A D S +D
Sbjct: 262 RDPTLRI-----TIPDIKEHEFFEEIDWDKLMAHDFEPPFKPTL-ANLEDVSHFD 310
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 206 bits (525), Expect = 4e-53
Identities = 110/302 (36%), Positives = 172/302 (56%), Gaps = 35/302 (11%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
+ ++ DF+I++ + G+FG+V L R G F+A+ E ERN+L
Sbjct: 664 RISIDDFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNILI 723
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
V +PF++R + +F L+++M+Y+ GG+L+SLL+K +A+ Y AE+ LALEY
Sbjct: 724 TVRYPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLALEY 783
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK------------YVPDVT--------- 297
LHS I++RDLKP+N+L+ NGHIKLTDFG +K + DV+
Sbjct: 784 LHSLKIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGLINNTIDLSGHESDVSPRTNSHHFQ 843
Query: 298 ---------YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKT 348
++ GTPDY+APE++ + + DWWS G++++E+L G PF S K
Sbjct: 844 KNQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTGIPPFTASRPEKI 903
Query: 349 YENILNAPVRFPPF---FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWE 405
++NILN + +P +AQDLI++L+ + +RLG NG+ +VK+HP+F V WE
Sbjct: 904 FDNILNGKMPWPDVPGEMSYEAQDLINRLLVHEPEKRLG--ANGAAEVKSHPFFQGVDWE 961
Query: 406 KL 407
L
Sbjct: 962 NL 963
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 206 bits (523), Expect = 8e-53
Identities = 130/355 (36%), Positives = 178/355 (49%), Gaps = 53/355 (14%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ +R LG G G+V LVR R YA+ + E+ +L+ +HPF
Sbjct: 496 FEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPF 555
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVCLALEYLHSK 262
I+ ++ +FQ L++ M+Y GGE F L RK++ A+FYA+EV ALEYLH
Sbjct: 556 IVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLL 615
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV------------------------TY 298
G IYRDLKPENILL ++GHI L+DF + D T
Sbjct: 616 GFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTN 675
Query: 299 TLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVR 358
+ GT +YIAPEV+ + +VDWW+ G+LIYEML G+TPF NT +T+ NIL V
Sbjct: 676 SFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVS 735
Query: 359 FP--PFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPY 416
FP +DLI KL+T++ S+RLG + G+ DVK HP+F +V W L +N E P
Sbjct: 736 FPNNNEISRTCKDLIKKLLTKNESKRLG-CKMGAADVKKHPFFKKVQWS--LLRNQEPPL 792
Query: 417 EPPI----------------QAGQGDTSQYDRYP----EEEVNYG--IQGEDPYH 449
P + Q Q D EE V Y + +DP+H
Sbjct: 793 IPVLSEDGYDFAKLSSNKKRQTSQDSHKHLDEQEKNMFEERVEYDDEVSEDDPFH 847
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 204 bits (520), Expect = 2e-52
Identities = 106/300 (35%), Positives = 177/300 (58%), Gaps = 7/300 (2%)
Query: 128 TSTLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXX 187
T +L+ + A+ + + + TLG G+FGRV LV +N + A+
Sbjct: 677 TKSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVA--YNQQALALKIIKKIEVVKQDQI 734
Query: 188 EHTNDERN-MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAK 246
EH +E+N M+ PFI++++ T+++ + ++ +M+ GG++++++ K Q F AK
Sbjct: 735 EHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAK 794
Query: 247 FYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV--PDVTYTLCGTP 304
F A V A +YLHS IYRDLKPEN++L +G+ KL DFGFAK+V + T T GTP
Sbjct: 795 FIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTP 854
Query: 305 DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNA--PVRFPPF 362
+Y+APE++ + ++++VD+W+ G+L+YE+L G TPF N IK Y+ IL+ + P
Sbjct: 855 EYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSR 914
Query: 363 FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
AQ L+ L + ++RLG + G D+K H WF + W++L K + +P + P+++
Sbjct: 915 IPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKS 974
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 203 bits (516), Expect = 5e-52
Identities = 111/350 (31%), Positives = 179/350 (50%), Gaps = 52/350 (14%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ K + DF +L +G G+FG V + R G+ YAM EH E
Sbjct: 113 RLQRHKLGVADFDLLTMIGKGAFGEVRVCREKTTGQVYAMKKLKKAEMLRRGQVEHVRAE 172
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
RN+L+ V +I++++ +FQD L+++M+Y+ GG++ +LL + AKFY AE
Sbjct: 173 RNLLAEVDSNYIVKLYCSFQDDDHLYLVMEYLPGGDMMTLLMRKDTLTEEEAKFYVAETV 232
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP------------------- 294
LA+E +H I+RD+KP+N+LLD+ GH++L+DFG K +
Sbjct: 233 LAIESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSAIGENDFSNNSNGSTEQ 292
Query: 295 -----------------------DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIY 331
+ Y+ GTPDYIAPEV+ K Y DWWS G ++Y
Sbjct: 293 EAGSTAPKRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 352
Query: 332 EMLAGYTPFYDSNTIKTYENILN--APVRFP--PFFHSDAQDLISKLITRDLSQRLGNLQ 387
EML GY PFY + + T I+N + ++FP +A+DLI+ L+ + +RLG+
Sbjct: 353 EMLVGYPPFYSDDPMSTCRKIVNWKSHLKFPEEAILSREAKDLINSLLC-SVRRRLGS-- 409
Query: 388 NGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEE 437
G++++K H WF V W+ + +++ + P + DT ++++ E E
Sbjct: 410 KGADELKAHTWFETVDWDTIF--DMDAAFVPEVN-DDLDTQNFEKFDESE 456
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 203 bits (516), Expect = 5e-52
Identities = 114/354 (32%), Positives = 179/354 (50%), Gaps = 58/354 (16%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ K + DF++L +G G+FG V + + G YAM EH E
Sbjct: 109 RLQRQKMGVDDFELLSIIGRGAFGEVRICKEKSTGSVYAMKKLKKSEMLRRGQVEHVKAE 168
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
RN+L+ V PFI+++ +FQD + L++IM+Y+ GG++ +LL + +FY A+
Sbjct: 169 RNVLAEVDSPFIVKLCYSFQDDEHLYLIMEYLPGGDMMTLLMRKDTLREDETRFYVAQTI 228
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV-----PD------------- 295
LA+E +H ++RD+KP+N+L+ +NGHIKL+DFG +K + PD
Sbjct: 229 LAIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLSKSLESKNFPDFKAELVDRSTKPA 288
Query: 296 ------------------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWS 325
+ ++ GTPDYIAPEV+ K Y DWWS
Sbjct: 289 AEHDRLSKPPSAPRRTQQEQLLHWQQNRRTLAFSTVGTPDYIAPEVLLKKGYGMECDWWS 348
Query: 326 FGVLIYEMLAGYTPFYDSNTIKTYENILN--APVRFP--PFFHSDAQDLISKLITRDLSQ 381
G +++EML G+ PFY + T I+N ++FP + +DLI +L+ ++ Q
Sbjct: 349 LGAIMFEMLVGFPPFYSEEPLATCRKIVNWKTCLKFPDEAKLSIEVKDLIRRLLC-NVEQ 407
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPE 435
RLG G ++K HPWF V WE+L N PY P ++ + DT ++++ E
Sbjct: 408 RLGT--KGVHEIKAHPWFRGVEWERLYESN--APYIPQVK-HELDTQNFEKFDE 456
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 203 bits (516), Expect = 5e-52
Identities = 113/325 (34%), Positives = 182/325 (55%), Gaps = 27/325 (8%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF I++ + G++G V+LV+ + +AM E ER++LS +P
Sbjct: 834 DFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNP 893
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F++ M+ +F+ + L ++M+Y+EGG+ +LL+ P +A+FY AE LA+EYLHS G
Sbjct: 894 FVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYG 953
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAK-------------YVPDVT-----YTLCGTPD 305
I++RDLKP+N+L+ GHIKLTDFG +K Y+ T + GTP+
Sbjct: 954 IVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPE 1013
Query: 306 YIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPF--- 362
YIAPEV+ + Y K VDWWS G+++YE L G PF+ T + + + +N + +P
Sbjct: 1014 YIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDW 1073
Query: 363 -FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQ 421
++A+D+IS+L+ ++ RLG Q+G+ ++K H +F + W LL + E P
Sbjct: 1074 PVQAEAKDIISQLLQQNPRDRLGT-QSGALEMKEHEYFLGMDWNSLLRQKAEF---VPQL 1129
Query: 422 AGQGDTSQYDRYPEEEVNYGIQGED 446
+ DTS +D + N+ + GED
Sbjct: 1130 SHDDDTSYFDT-RMDRYNHDLGGED 1153
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 202 bits (514), Expect = 8e-52
Identities = 120/332 (36%), Positives = 170/332 (51%), Gaps = 40/332 (12%)
Query: 143 YDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSH 202
+ F+ +R LG G G+V+LVR N R +AM E+ +L+ H
Sbjct: 153 HSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKH 212
Query: 203 PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQR--FPNPVAKFYAAEVCLALEYLH 260
PFI+ ++ +FQ L++ M+Y GGE F L + P A FYAAEV ALEYLH
Sbjct: 213 PFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLH 272
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY---------------------- 298
G IYRDLKPENILL ++GHI L+DF +K + VT+
Sbjct: 273 LMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDTNS 332
Query: 299 --------TLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYE 350
+ GT +YIAPEV+ + + +VDWW+ G+ IYE+L G TPF N T+
Sbjct: 333 YFSNFRTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNRHATFS 392
Query: 351 NILNAPVRFP-----PFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWE 405
NIL + V FP P S + LI +L+ +D S+R G++ G+ D+K HP+F + W
Sbjct: 393 NILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVA-GASDIKQHPFFRHIQW- 450
Query: 406 KLLCKNIETPYEPPIQAGQGDTSQYDRYPEEE 437
L ++++ P P I+ G D EEE
Sbjct: 451 -ALLRSMKPPIIPKIEDGMEAVEPSDNDNEEE 481
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 202 bits (514), Expect = 8e-52
Identities = 117/348 (33%), Positives = 174/348 (49%), Gaps = 50/348 (14%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ + L DF+ L+ +G G+FG V LV+ G YAM H E
Sbjct: 79 RLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAE 138
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
R++L ++++M+ +FQD + L++IM+++ GG++ +LL K +FY +E
Sbjct: 139 RDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETV 198
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFG------------------------- 288
LA++ +H G I+RD+KP+N+LLD GH+KL+DFG
Sbjct: 199 LAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDF 258
Query: 289 -------------FAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLA 335
+ K + Y+ GTPDYIAPEV YNK DWWS GV++YEML
Sbjct: 259 SFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLI 318
Query: 336 GYTPFYDSNTIKTYENILN--APVRFPPF--FHSDAQDLISKLITRDLSQRLGNLQNGSE 391
GY PF +TY ++N + FPP A+DLI + D R+GN +G E
Sbjct: 319 GYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCI-DSENRIGN--SGVE 375
Query: 392 DVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQ-GDTSQYDRYPEEEV 438
++K HP+F V WE + E P PI+ DTS +D +PE ++
Sbjct: 376 EIKGHPFFEGVDWEHIR----ERPAAIPIEIKSIDDTSNFDDFPESDI 419
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 201 bits (512), Expect = 1e-51
Identities = 103/300 (34%), Positives = 170/300 (56%), Gaps = 33/300 (11%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
+ ++ DF++++++ G+FG V L R N G +A+ E ER++L
Sbjct: 822 RISIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDILI 881
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
+PF++R + +F S+ L+++M+Y+ GG+ +S+LRK A+ Y AEV LALEY
Sbjct: 882 NARNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIAEVVLALEY 941
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY-------------------------- 292
LHS+G+++RDLKP+N+L+ +GH+KLTDFG +K
Sbjct: 942 LHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPK 1001
Query: 293 VPDVTY--TLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYE 350
+P + + + GTPDY+APE++ + + DWWS G+++YE L G PF + + ++
Sbjct: 1002 LPTLDHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVGIPPFNADHPQQIFD 1061
Query: 351 NILNAPVRFPPF---FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKL 407
NILN +++PP +A+DLI +L+T D QRLG G+ +VK H +F ++ W L
Sbjct: 1062 NILNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQRLG--ARGAAEVKQHSFFKDIDWNTL 1119
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 201 bits (510), Expect = 2e-51
Identities = 113/301 (37%), Positives = 169/301 (55%), Gaps = 28/301 (9%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ +R LG G G+V+L+R + +A+ + E+ +L+ HPF
Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPF 383
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVCLALEYLHSK 262
I+ ++ +FQ L++ M+Y GGE F L RKS+ AKFYA+EV ALEYLH
Sbjct: 384 IVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLL 443
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA--------KYVPDVTY-------------TLC 301
G IYRDLKPENILL ++GH+ L+DF + + D TY +
Sbjct: 444 GFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFV 503
Query: 302 GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP- 360
GT +Y+APEV+ + +VDWW+ G+LIYEML G TPF N+ +T+ NIL V+FP
Sbjct: 504 GTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPH 563
Query: 361 -PFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPP 419
+ +DLI KL+ ++ ++RLG+ ++G+ D+K HP+F +V W L +N + P P
Sbjct: 564 DKEVSKNCKDLIKKLLNKNEAKRLGS-KSGAADIKRHPFFKKVQWSFL--RNQDPPLIPA 620
Query: 420 I 420
+
Sbjct: 621 L 621
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 201 bits (510), Expect = 2e-51
Identities = 109/324 (33%), Positives = 179/324 (54%), Gaps = 26/324 (8%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ ++ + G++G V+LVR + +A+ + ER++L+ +P
Sbjct: 196 DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENP 255
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F++ M+ +F+ + L M+M+Y+EGG+ +LL+ P +A+ Y AE LALEYLH+ G
Sbjct: 256 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYG 315
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY------------------VPDVTYTLCGTPD 305
I++RDLKP+N+L+ GHIKLTDFG +K + +CGTP+
Sbjct: 316 IVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPE 375
Query: 306 YIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP---PF 362
YIAPEV+ + Y K VDWW+ GV++YE L G PF+ + + +++ + +P
Sbjct: 376 YIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEA 435
Query: 363 FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
+DAQDLI++L+ + RLG G+ +VK HP+F + W LL E + P ++A
Sbjct: 436 LPADAQDLITRLLRQSPLDRLGT--GGTHEVKQHPFFLALDWAGLLRHKAE--FVPQLEA 491
Query: 423 GQGDTSQYDRYPEEEVNYGIQGED 446
+ DTS +D E + G + ++
Sbjct: 492 -EDDTSYFDTRSERYRHLGSEDDE 514
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 200 bits (508), Expect = 4e-51
Identities = 118/339 (34%), Positives = 183/339 (53%), Gaps = 41/339 (12%)
Query: 141 ALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
++ DF+I++ + G+FGRV L + G +A+ E ERN+L V
Sbjct: 750 SIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAERNILISV 809
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
+PF++R + +F + L+++M+Y+ GG+LFSLLR +A+ Y AEV LALEYLH
Sbjct: 810 RNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALEYLH 869
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKY-----VPDVT------------------ 297
S II+RDLKP+N+L++++GHIKLTDFG +K D++
Sbjct: 870 SVNIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAEDGSKA 929
Query: 298 -----------YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTI 346
+ + GTPDY+APE++ + K+ DWWS GV+++E+L G PF
Sbjct: 930 QHSQGKDSRKKHAVVGTPDYLAPEILLGMGHGKTADWWSVGVILFEVLVGIPPFNAETPQ 989
Query: 347 KTYENILNAPVRFPPF---FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVV 403
+ +ENI+N + +P +A DLI+KL+T + QRLG G+ +VK H +F ++
Sbjct: 990 QIFENIINRDIPWPNVPEEISYEAHDLINKLLTENPVQRLG--ATGAGEVKQHHFFKDIN 1047
Query: 404 WEKLL-CKNIETPYEPPIQAGQGDTSQYDRYPEEEVNYG 441
W+ L K + P P Q S+Y PE+E +G
Sbjct: 1048 WDTLARQKAMFVPSAEP-QDTSYFMSRYIWNPEDENVHG 1085
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 199 bits (507), Expect = 5e-51
Identities = 106/296 (35%), Positives = 162/296 (53%), Gaps = 8/296 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L DF+ L LG G FG+V LV+ G++YA+ E E+ +L V
Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615
Query: 202 ---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
HPF++ + FQ S + +++ GG+L + + FP P A+FY A V L L++
Sbjct: 616 CTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHEDV-FPEPQARFYVACVVLGLQF 674
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTK 315
LH K IIYRDLK +N+LLD G +K+ DFG K D T T CGTP+++APEV++ +
Sbjct: 675 LHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQE 734
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
Y ++VDWW+ GVL+YEML G PF + ++ I+N +P F + I KL+
Sbjct: 735 AYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLL 794
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+ +RLG + +E++K P+F W+ LL + I+ P+ P + G D ++
Sbjct: 795 QKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTL-CGPADLRYFE 849
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 199 bits (507), Expect = 5e-51
Identities = 112/342 (32%), Positives = 173/342 (49%), Gaps = 56/342 (16%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ L +G G+FG V + R G YAM EH ERN+L+ V
Sbjct: 119 DFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSN 178
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I++++ +FQD + L++IM+Y+ GG++ +LL + A+FY E LA+E +H
Sbjct: 179 CIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYVGETVLAIESIHKHN 238
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVP----------------------------- 294
I+RD+KP+N+LLD++GH+KL+DFG K +
Sbjct: 239 YIHRDIKPDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAHNLSGALQSDGRPVAPR 298
Query: 295 -----------------DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGY 337
+ Y+ GTPDYIAPEV+ K Y DWWS G ++YEML G+
Sbjct: 299 RTRSQMEQLQNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGF 358
Query: 338 TPFYDSNTIKTYENILNAP--VRFPP--FFHSDAQDLISKLITRDLSQRLGNLQNGSEDV 393
PFY + T I+N ++FP +A+DLI +L+ ++ QR+G G+ ++
Sbjct: 359 PPFYSDEPMTTCRKIVNWKNYLKFPDEVRLSPEAKDLICRLLC-NVEQRIGT--KGANEI 415
Query: 394 KNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPE 435
K HPWFS V WEKL ++ + P + + DT ++++ E
Sbjct: 416 KEHPWFSGVEWEKLY--QMKAAFIPQVN-DELDTQNFEKFEE 454
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 199 bits (506), Expect = 7e-51
Identities = 121/313 (38%), Positives = 165/313 (52%), Gaps = 40/313 (12%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ + LG G GRV+LVR +G+FYAM + E+++L+ +HPF
Sbjct: 195 FEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPF 254
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVCLALEYLHSK 262
I+ ++ +FQ + L++ M+Y GGE F L R + AKFY AEV ALEYLH
Sbjct: 255 IVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLM 314
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAK----------------------YVPDV---- 296
G IYRDLKPENILL ++GHI L+DF +K Y D
Sbjct: 315 GFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCI 374
Query: 297 ----TYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENI 352
T + GT +YIAPEV+ + +VDWW+ G+L YEML TPF N T+ NI
Sbjct: 375 ADFRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNI 434
Query: 353 LNAPVRFP-----PFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKL 407
L+ V FP P S ++LI KL+ +D + RLG+ Q G+ DVK HP+F V W
Sbjct: 435 LHKDVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGS-QAGAADVKLHPFFKNVQW--A 491
Query: 408 LCKNIETPYEPPI 420
L ++ E P P +
Sbjct: 492 LLRHTEPPIIPKL 504
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 199 bits (505), Expect = 9e-51
Identities = 116/303 (38%), Positives = 170/303 (55%), Gaps = 21/303 (6%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+IL+ +G G+FG V +V+ + + +AM +ER++L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCLALEYLHSK 262
+I + FQD L+++MDY GG+L +LL K + R P +A+FY AE+ +A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPDVTY---TLCGTPDYIAPEVVSTKP-- 316
++RD+KP+NIL+D NGHI+L DFG K + D T GTPDYI+PE++
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 317 ---YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP-----PFFHSDAQ 368
Y DWWS GV +YEML G TPFY + ++TY I+N RF +A+
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 369 DLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTS 428
DLI +LI RLG QNG ED K HP+FS + W+ + +N E PY P + + DTS
Sbjct: 316 DLIRRLIC-SREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEV-SSPTDTS 369
Query: 429 QYD 431
+D
Sbjct: 370 NFD 372
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 199 bits (505), Expect = 9e-51
Identities = 108/324 (33%), Positives = 182/324 (55%), Gaps = 26/324 (8%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ ++ + G++G V+ VR + + +AM + ER++L+ +P
Sbjct: 38 DFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 97
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F++ M+ +F+ + L M+M+Y+EGG+ +L++ P +A+ Y AE LALEYLH+ G
Sbjct: 98 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 157
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY-VPDVTYTL-----------------CGTPD 305
I++RDLKP+N+L+ GHIKLTDFG +K + +T L CGTP+
Sbjct: 158 IVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPE 217
Query: 306 YIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHS 365
YIAPEV+ + Y K VDWW+ G+++YE L G PF+ + + +++ + +P +
Sbjct: 218 YIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEA 277
Query: 366 ---DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
DAQDLI+ L+ ++ +RLG G+ +VK H +F + W LL + E + P +++
Sbjct: 278 PPPDAQDLITLLLRQNPLERLGT--GGAYEVKQHRFFRSLDWNSLLRQKAE--FIPQLES 333
Query: 423 GQGDTSQYDRYPEEEVNYGIQGED 446
+ DTS +D E+ + + ED
Sbjct: 334 -EDDTSYFDTRSEKYHHMETEEED 356
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 199 bits (505), Expect = 9e-51
Identities = 108/295 (36%), Positives = 166/295 (55%), Gaps = 7/295 (2%)
Query: 148 LRTLGTGSFGRVHLVRSNHN-GRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPFII 206
L TLG G FGRV LV N + + +A+ EH ERN++ S +I+
Sbjct: 429 LATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIV 488
Query: 207 RMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIY 266
+++ TF+D + ++M+++ GGEL++ LR F + A+FY A V LEYLH K I+Y
Sbjct: 489 KLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVY 548
Query: 267 RDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNKSVDWW 324
RDLKPEN LL G++KL DFGFAK + T+T CGTP+Y++PE++ K ++++ D+W
Sbjct: 549 RDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYW 608
Query: 325 SFGVLIYEMLAGYTPFYDSNTIKTYENILNA--PVRFP-PFFHSDAQDLISKLITRDLSQ 381
+ G+ I E++ G PF S+ +KTY IL + P A L+ KL + +
Sbjct: 609 ALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGE 668
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
RLG+ G D++ H WF WE L + ++ P P + + D + +D YP +
Sbjct: 669 RLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKV-SNPADVTNFDNYPPD 722
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 199 bits (505), Expect = 9e-51
Identities = 108/295 (36%), Positives = 166/295 (55%), Gaps = 7/295 (2%)
Query: 148 LRTLGTGSFGRVHLVRSNHN-GRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPFII 206
L TLG G FGRV LV N + + +A+ EH ERN++ S +I+
Sbjct: 472 LATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIV 531
Query: 207 RMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIY 266
+++ TF+D + ++M+++ GGEL++ LR F + A+FY A V LEYLH K I+Y
Sbjct: 532 KLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVY 591
Query: 267 RDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNKSVDWW 324
RDLKPEN LL G++KL DFGFAK + T+T CGTP+Y++PE++ K ++++ D+W
Sbjct: 592 RDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYW 651
Query: 325 SFGVLIYEMLAGYTPFYDSNTIKTYENILNA--PVRFP-PFFHSDAQDLISKLITRDLSQ 381
+ G+ I E++ G PF S+ +KTY IL + P A L+ KL + +
Sbjct: 652 ALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGE 711
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
RLG+ G D++ H WF WE L + ++ P P + + D + +D YP +
Sbjct: 712 RLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKV-SNPADVTNFDNYPPD 765
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 198 bits (504), Expect = 1e-50
Identities = 114/303 (37%), Positives = 168/303 (54%), Gaps = 21/303 (6%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+I++ +G G+FG V +V+ + R YAM +ER++L
Sbjct: 75 DFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQ 134
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCLALEYLHSK 262
+I + FQD L+++MDY GG+L +LL K + + P +A+FY E+ LA++ +H
Sbjct: 135 WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQL 194
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD----VTYTLCGTPDYIAPEVVSTK--- 315
++RD+KP+N+LLD NGHI+L DFG + D + GTPDYI+PE++
Sbjct: 195 HYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDG 254
Query: 316 --PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFH-----SDAQ 368
Y DWWS GV +YEML G TPFY + ++TY I+N RF H +A+
Sbjct: 255 MGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAK 314
Query: 369 DLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTS 428
DLI +LI +RLG QNG ED K H +F + WE + +N+E PY P + + DTS
Sbjct: 315 DLIQRLIC-SRERRLG--QNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDV-SSPSDTS 368
Query: 429 QYD 431
+D
Sbjct: 369 NFD 371
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 197 bits (501), Expect = 3e-50
Identities = 110/306 (35%), Positives = 174/306 (55%), Gaps = 17/306 (5%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
D+++++ +G G+FG V LVR + YAM +ER++++ + P
Sbjct: 75 DYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSP 134
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
++++++ FQD + L+M+M+Y+ GG+L +L+ + P A+FY AEV LAL+ +HS G
Sbjct: 135 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM-SNYDVPEKWARFYTAEVVLALDAIHSMG 193
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLC----GTPDYIAPEVVSTKP--- 316
I+RD+KP+N+LLDK+GH+KL DFG + C GTPDYI+PEV+ ++
Sbjct: 194 FIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDG 253
Query: 317 -YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN--APVRFPP--FFHSDAQDLI 371
Y + DWWS GV +YEML G TPFY + + TY I+N + FP +A++LI
Sbjct: 254 YYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLI 313
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+T D RLG +NG E++K H +F W ++ P P + + DTS +D
Sbjct: 314 CAFLT-DREVRLG--RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDL-SSDIDTSNFD 369
Query: 432 RYPEEE 437
E++
Sbjct: 370 DLEEDK 375
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 197 bits (501), Expect = 3e-50
Identities = 113/342 (33%), Positives = 174/342 (50%), Gaps = 54/342 (15%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ L +G G+FG V + R G YAM EH ERN+L+ V
Sbjct: 42 DFEPLTMIGKGAFGEVRICREKGTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSN 101
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I++++ +FQD + L++IM+Y+ GG++ +LL + A+FY E LA+E +H
Sbjct: 102 CIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYIGETVLAIESIHKHN 161
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYV-------PDVT------------------- 297
I+RD+KP+N+LLDK+GH+KL+DFG K + D T
Sbjct: 162 YIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCSNLQEKDFTVARNVSGALQSDGRPVATR 221
Query: 298 ------------------YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTP 339
Y+ GTPDYIAPEV+ K Y DWWS G ++YEML G+ P
Sbjct: 222 RTQQEQLLNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGFPP 281
Query: 340 FYDSNTIKTYENILN--APVRFPP--FFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKN 395
FY + + T I+N ++FP +A+DLI +L+ ++ QRLG G++++K
Sbjct: 282 FYSDDPMTTCRKIVNWRNYLKFPDEVRLSPEAKDLICRLLC-NVEQRLGT--KGADEIKG 338
Query: 396 HPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEE 437
HPWF W KL ++ + P + + DT ++++ E +
Sbjct: 339 HPWFRGTEWGKLY--QMKAAFIPQVN-DELDTQNFEKFEETD 377
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 196 bits (499), Expect = 5e-50
Identities = 106/315 (33%), Positives = 169/315 (53%), Gaps = 15/315 (4%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
+ +DF++ + G GS+ +V + NG YA+ + ER +L
Sbjct: 37 FTYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQ 96
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
+ HP I++++ TFQD+Q L+M ++ EGGELF + + R A+FY+AEV ALEY+
Sbjct: 97 LEHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALEYI 156
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTL-------------CGTPDY 306
H+ G+I+RD+KPEN+LL +GHIK+ DFG K + D T+ GT Y
Sbjct: 157 HNMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAY 216
Query: 307 IAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD 366
+ PEV+++ P D W+ G +Y+ML+G +PF D++ ++ I+ ++FP F
Sbjct: 217 VPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEA 276
Query: 367 AQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGD 426
A+DLI +L+ D S+R G G + +K HP+F V W+ L ++ P P A Q
Sbjct: 277 ARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWKNL--RSQTPPKLAPDPASQSA 334
Query: 427 TSQYDRYPEEEVNYG 441
+ + D P + G
Sbjct: 335 SPERDGSPWNPTHVG 349
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 196 bits (498), Expect = 6e-50
Identities = 108/313 (34%), Positives = 174/313 (55%), Gaps = 26/313 (8%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ ++ + G++G V LVR + +AM + ER++L+ +P
Sbjct: 511 DFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 570
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F++ M+ +F + L M+M+Y+EGG+ +LL+ P + + Y AE LALEYLH+ G
Sbjct: 571 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 630
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY-VPDVTYTL-----------------CGTPD 305
I++RDLKP+N+L+ GHIKLTDFG +K + +T L CGTP+
Sbjct: 631 IVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPE 690
Query: 306 YIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP---PF 362
YIAPEV+ + Y K VDWW+ G+++YE L G PF+ + + +++ + +P
Sbjct: 691 YIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDEA 750
Query: 363 FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
DAQDL SKL+ ++ +RLG + +VK HP+F+ + W LL + E + P +++
Sbjct: 751 LPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE--FIPQLES 806
Query: 423 GQGDTSQYDRYPE 435
+ DTS +D E
Sbjct: 807 -EDDTSYFDTRSE 818
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 196 bits (497), Expect = 8e-50
Identities = 108/306 (35%), Positives = 175/306 (56%), Gaps = 17/306 (5%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
D+ +++ +G G+FG V LVR + + YAM +ER++++ + P
Sbjct: 91 DYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSP 150
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
++++++ FQD + L+M+M+Y+ GG+L +L+ + P AKFY AEV LAL+ +HS G
Sbjct: 151 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM-SNYDVPEKWAKFYTAEVVLALDAIHSMG 209
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLC----GTPDYIAPEVVSTKP--- 316
+I+RD+KP+N+LLDK+GH+KL DFG + + C GTPDYI+PEV+ ++
Sbjct: 210 LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
Query: 317 -YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN--APVRFP--PFFHSDAQDLI 371
Y + DWWS GV +YEML G TPFY + + TY I++ + FP A++LI
Sbjct: 270 FYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLI 329
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+T D RLG +NG E+++ HP+F W + P P + + D+S +D
Sbjct: 330 CAFLT-DREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPEL-SSDIDSSNFD 385
Query: 432 RYPEEE 437
+++
Sbjct: 386 DIEDDK 391
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 196 bits (497), Expect = 8e-50
Identities = 108/306 (35%), Positives = 175/306 (56%), Gaps = 17/306 (5%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
D+ +++ +G G+FG V LVR + + YAM +ER++++ + P
Sbjct: 91 DYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSP 150
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
++++++ FQD + L+M+M+Y+ GG+L +L+ + P AKFY AEV LAL+ +HS G
Sbjct: 151 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM-SNYDVPEKWAKFYTAEVVLALDAIHSMG 209
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLC----GTPDYIAPEVVSTKP--- 316
+I+RD+KP+N+LLDK+GH+KL DFG + + C GTPDYI+PEV+ ++
Sbjct: 210 LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
Query: 317 -YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN--APVRFP--PFFHSDAQDLI 371
Y + DWWS GV +YEML G TPFY + + TY I++ + FP A++LI
Sbjct: 270 FYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLI 329
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+T D RLG +NG E+++ HP+F W + P P + + D+S +D
Sbjct: 330 CAFLT-DREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPEL-SSDIDSSNFD 385
Query: 432 RYPEEE 437
+++
Sbjct: 386 DIEDDK 391
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 194 bits (494), Expect = 2e-49
Identities = 103/270 (38%), Positives = 152/270 (56%), Gaps = 6/270 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ + LG GSF V L R R YA+ + ER+++S + HP
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F ++++ TFQD ++L+ + Y + GEL +RK F +FY AE+ ALEYLH KG
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT-----YTLCGTPDYIAPEVVSTKPYN 318
II+RDLKPENILL+++ HI++TDFG AK + + + GT Y++PE+++ K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
KS D W+ G +IY+++AG PF N ++ I+ FP F A+DL+ KL+ D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 379 LSQRLG-NLQNGSEDVKNHPWFSEVVWEKL 407
++RLG G +K HP+F V WE L
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 194 bits (494), Expect = 2e-49
Identities = 108/320 (33%), Positives = 176/320 (54%), Gaps = 19/320 (5%)
Query: 137 SGKYA--LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDER 194
S K+A L DF++L +G GS+ +V + YA+ + E+
Sbjct: 243 SSKWAVSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEK 302
Query: 195 NMLSIVS-HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
++ S +PF++ + FQ +LF +++++ GG+L +++ ++ P A+FY+ E+
Sbjct: 303 SVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEII 362
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPE 310
LAL +LHS+GIIYRDLK +N+L+D GHIKLTD+G K D+T T CGTP+YIAPE
Sbjct: 363 LALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPE 422
Query: 311 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYEN--------ILNAPVRFPPF 362
++ Y SVDWW+ GVL++EM+AG +PF + EN IL +R P
Sbjct: 423 ILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRS 482
Query: 363 FHSDAQDLISKLITRDLSQRLG---NLQNGSEDVKNHPWFSEVV-WEKLLCKNIETPYEP 418
A ++ + +D ++RLG ++ G D+K H +F + WE L K + PY P
Sbjct: 483 LSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHP 542
Query: 419 PIQAGQGDTSQYDRYPEEEV 438
+++ + D + +D +E+
Sbjct: 543 AVESDR-DLTHFDHQFTDEL 561
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 194 bits (493), Expect = 2e-49
Identities = 109/324 (33%), Positives = 175/324 (53%), Gaps = 30/324 (9%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF +R + G++G V+LVR + +A+ + ER++L++ +P
Sbjct: 357 DFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNP 416
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F++ +G+F+ Q L M+M+Y+EGG+ +LL+ + P + + Y AE LA+EYLHS G
Sbjct: 417 FVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSYG 476
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY------------VPDVTYT-------LCGTP 304
I++RDLKP+N+L+ GHIKLTDFG +K V T LCGTP
Sbjct: 477 IVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTP 536
Query: 305 DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP---P 361
+YIAPEV+ + Y K VDWW+ G+++YE L G PF+ + +++ V +P
Sbjct: 537 EYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEEDE 596
Query: 362 FFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQ 421
+A DL +L+ ++ ++RLG L NG+ + H +F + + LL + E + P +
Sbjct: 597 ALPPEAADLCRRLLEKNPAERLGTL-NGAAQLMAHEFFILLDFTSLLRQKAE--FVPQLD 653
Query: 422 AGQGDTSQY----DRYPEEEVNYG 441
+ DTS + DRY E + G
Sbjct: 654 -NEEDTSYFDTRTDRYNHEAESCG 676
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 193 bits (491), Expect = 4e-49
Identities = 104/300 (34%), Positives = 172/300 (56%), Gaps = 8/300 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K +L +F +L+ LG G+FG+V L +S + R A+ E E+ +
Sbjct: 818 KVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFL 877
Query: 199 IVS---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+ + HPF+ ++ +FQ +++ M++I GG+L ++ +QR AKFYAAEV LA
Sbjct: 878 LATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQ-NQRLSVRRAKFYAAEVLLA 936
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK---YVPDVTYTLCGTPDYIAPEVV 312
L+Y H G+IYRDLK ENILL GHIK+ D+G K + + T T CGTP+++APE++
Sbjct: 937 LKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEIL 996
Query: 313 STKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLIS 372
+ Y K+VDWW+FGVL+Y+ML +PF + + + IL +P + +
Sbjct: 997 KEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQ 1056
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDR 432
L+T+D +RLG +++V P+F + ++ +L ++ PY P I++ + DTS +++
Sbjct: 1057 GLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPE-DTSYFEQ 1115
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 191 bits (486), Expect = 1e-48
Identities = 113/353 (32%), Positives = 172/353 (48%), Gaps = 55/353 (15%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ + + DF+ L+ +G G+FG V LV+ + G YAM H E
Sbjct: 69 RLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAE 128
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
R++LS ++++M+ +FQD L+++M+++ GG++ +LL K +FY AE
Sbjct: 129 RDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQFYIAEAA 188
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGF-----------------AKYVPD- 295
LA++++HS G I+RD+KP+N+LLD GH+KL+DFG + PD
Sbjct: 189 LAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWPSTLPPDF 248
Query: 296 --------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLA 335
Y+ GTPDYIAPEV Y KS DWWS GV++YEML
Sbjct: 249 ISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLI 308
Query: 336 GYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLIS-----KLITRDLSQRLGNLQNGS 390
GY PF +TY ++N F SD I K + +RLGN G
Sbjct: 309 GYPPFCSELPQETYRKVINWQQTL--VFPSDVPISIEAKATIKRFCCEAERRLGN-HGGL 365
Query: 391 EDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA---GQGDTSQYDRYPEEEVNY 440
+++K P+ + W + E P PPI+ DTS +D +P+E++ +
Sbjct: 366 DEIKQCPFVKRIDWNHIR----ERP--PPIRVTVKSIDDTSNFDDFPDEDLTW 412
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 191 bits (486), Expect = 1e-48
Identities = 103/305 (33%), Positives = 171/305 (55%), Gaps = 11/305 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS--- 201
F+++ LG G FG+V L + N +YA+ E E+ + + S
Sbjct: 690 FRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSRAR 749
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HPF++ + G FQ ++ +F M+Y GG+L + F FYAA V L L++LH
Sbjct: 750 HPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDV-FDEVRGCFYAACVVLGLDFLHK 808
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYN 318
IIYRD+K +N+LLD+ G++K+ DFG K D T T CGTP+++APEV+S Y
Sbjct: 809 HNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDSSYT 868
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+++DWW GVLI+EML G PF + + +++I++ VR+P + ++ ++ +L+ +
Sbjct: 869 RAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLLRKV 928
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWE--KLLCKNIETPYEPPIQAGQGDTSQYD-RYPE 435
+RLG + +ED+K +F + WE KLL + I P++P I+ + D S +D + +
Sbjct: 929 PEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPE-DVSNFDLEFTQ 987
Query: 436 EEVNY 440
E+ +
Sbjct: 988 EKARF 992
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 190 bits (482), Expect = 4e-48
Identities = 101/301 (33%), Positives = 163/301 (53%), Gaps = 39/301 (12%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+I++ + G+FGRV L + G +A+ E ER++L V +P
Sbjct: 889 DFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNAVESILAERDILINVRNP 948
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
F++R + +F L+++M+Y+ GG+L+SLLR + + Y AEV LALEYLHS+G
Sbjct: 949 FVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLALEYLHSEG 1008
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKY----------VPDVTYT-------------- 299
+++RDLKP+N+L+ +GHIKLTDFG +K P V+ T
Sbjct: 1009 VVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLAASE 1068
Query: 300 ----------LCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTY 349
GTPDY+APE++ + + DWWS G++++E++ G PF + + +
Sbjct: 1069 EQLERRKKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILFELIVGIPPFNAEHPQQIF 1128
Query: 350 ENILNAPVRFPPF---FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEK 406
+NILN + +P ++A D+I + +T D QRLG G+ +VK H +F ++ W+
Sbjct: 1129 DNILNRKIPWPHVPEEMSAEAHDIIDRFLTEDPHQRLG--ARGAAEVKQHIFFKDINWDT 1186
Query: 407 L 407
L
Sbjct: 1187 L 1187
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 190 bits (482), Expect = 4e-48
Identities = 110/338 (32%), Positives = 166/338 (48%), Gaps = 52/338 (15%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ L+ +G G+FG V LV+ G YAM H ER++L H
Sbjct: 92 DFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEADHQ 151
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
++++M+ +FQD L++IM+++ GG++ +LL K +FY +E LA++ +H G
Sbjct: 152 WVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLG 211
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---------------------------- 295
I+RD+KP+N+LLD GH+KL+DFG +
Sbjct: 212 FIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASPMDS 271
Query: 296 -------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYD 342
+ Y+ GTPDYIAPEV Y + DWWS GV++YEML GY PF
Sbjct: 272 KRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCS 331
Query: 343 SNTIKTYENILN--APVRFPPF--FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPW 398
N TY ++N + FPP +A++ I + +RLG+ Q G ED+K+ P+
Sbjct: 332 DNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCC-EADRRLGS-QRGLEDLKSVPF 389
Query: 399 FSEVVWEKLLCKNIETPYEPPIQAGQ-GDTSQYDRYPE 435
F V WE + E P P++ DTS +D +P+
Sbjct: 390 FRGVDWEHIR----ERPAAIPVEVRSIDDTSNFDEFPD 423
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 189 bits (481), Expect = 6e-48
Identities = 109/300 (36%), Positives = 164/300 (54%), Gaps = 17/300 (5%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+ L+ +G G+FG VHLVR YAM +ER++++ +
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSE 126
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
+I+R+ FQD + L+M+M+Y+ GG+L +L+ S +FY AE+ AL LHS G
Sbjct: 127 WIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMT-SYEVSEKWTRFYTAEIVEALAALHSMG 185
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLC----GTPDYIAPEVVSTK---- 315
I+RD+KP+N+L+ +GHIKL DFG + C GTPDYI+PEV+ +
Sbjct: 186 YIHRDVKPDNMLISISGHIKLADFGTCVKMNANGVVRCSTAVGTPDYISPEVLRNQGQDA 245
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN--APVRFP--PFFHSDAQDLI 371
+ K VDWWS GV IYEML G TPFY + TY NI+N ++FP P + A+D+I
Sbjct: 246 EFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQAKDII 305
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
K ++ RLG +N +D++NH +F W + P P +++ DT+ ++
Sbjct: 306 KKFLSA-APDRLG--RNSVDDIRNHKFFVNDEWTFATLREASPPVIPSLKS-DDDTTHFE 361
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 189 bits (480), Expect = 7e-48
Identities = 114/358 (31%), Positives = 180/358 (49%), Gaps = 58/358 (16%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ K + F ++ +G G+FG+V LVR N + YAM H E
Sbjct: 491 RLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAE 550
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
R++L+ P+I+R++ +FQD L+ IM+Y+ GG++ +LL + F +A+FY AE+
Sbjct: 551 RDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAELA 610
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK----------YVPD-------- 295
A+EY+H+ G I+RDLKP+NIL+D++GHIKLTDFG Y P+
Sbjct: 611 CAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDS 670
Query: 296 --------------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVL 329
++L GT +Y+APEV++ +N+S DWWS GV+
Sbjct: 671 FSLPPEVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVI 730
Query: 330 IYEMLAGYTPFYD------SNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQRL 383
+YEM+ G PF+D + IK + N L+ + + +I +LI D S RL
Sbjct: 731 LYEMVFGRVPFHDDTPGGTQHRIKNWRNFLD--FTYCGNLSKECLMMIQQLIC-DASSRL 787
Query: 384 G----NLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEE 437
G ++ + VKNHPWF + W L + Y P + + DTS ++ + + +
Sbjct: 788 GSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHDE-DTSNFETFQDND 844
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 188 bits (477), Expect = 2e-47
Identities = 106/297 (35%), Positives = 170/297 (56%), Gaps = 17/297 (5%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRS----NHNGRFYAMXXXXXXXXXXXXXXEHTNDER 194
K ++ +F +LR LG G++G+V LVR +HN + EHT ER
Sbjct: 11 KVSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAER 70
Query: 195 NMLS-IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
+L + PF++ ++ FQ +L ++M+Y+ GGELF+ L F A+F AE+
Sbjct: 71 QVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELV 130
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAK-YVP---DVTYTLCGTPDYIAP 309
+A++ LH + +IYRDLK ENILLD+ GH+KLTDFG +K ++P D + CGT +Y++P
Sbjct: 131 VAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMSP 190
Query: 310 EVVSTKP--YNKSVDWWSFGVLIYEMLAGYTPF----YDSNTIKTYENILNAPVRFPPFF 363
EV++ Y+ VDWWS GV+ +E+L G +PF +++ + I+ V FP
Sbjct: 191 EVINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTM 250
Query: 364 HSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPI 420
DA+D I +L+ + L +RLG NG +++KNH + S + W+ + + ++ P I
Sbjct: 251 DVDARDFIGQLLEKKLEKRLG--YNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRI 305
Score = 110 bits (275), Expect = 4e-24
Identities = 82/309 (26%), Positives = 138/309 (44%), Gaps = 57/309 (18%)
Query: 151 LGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPFIIRMWG 210
LG G+F V +G +A+ + + R + + HP I+++
Sbjct: 388 LGKGAFSVVRRCERVVDGAQFAVKIVSQKFAS-----QAQREARILEMVQGHPNIVQLHD 442
Query: 211 TFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIYRDLK 270
D +++M+ + G EL +RK +RF A ++ A++YLH K I++RDLK
Sbjct: 443 VHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVHRDLK 502
Query: 271 PENIL---LDKNGHIKLTDFGFAKYVPDV-------------------------TYTLCG 302
PENIL +D + ++L DFGFA+ +P+ + T C
Sbjct: 503 PENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPCF 562
Query: 303 TPDYIAPEVV----STKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVR 358
T Y APEV+ S YN+ D WS GV+++ ML+G PF+ + ++ I+ R
Sbjct: 563 TLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRICR 622
Query: 359 FPPFF--------HSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCK 410
F +DA++LI+ L+T D +RL +++ H W
Sbjct: 623 AEFSFTGDAWTNVSADAKNLITGLLTVDPKKRL-----SMQELTAHMWLKS-------SA 670
Query: 411 NIETPYEPP 419
+++TP + P
Sbjct: 671 SMDTPLQTP 679
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 188 bits (477), Expect = 2e-47
Identities = 104/315 (33%), Positives = 164/315 (52%), Gaps = 21/315 (6%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
+ +DF+ + G GS+ +V + G YA+ + ER +L
Sbjct: 36 FTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQ 95
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
+ HP II+++ TFQD+ L+M ++ EGGELF + + R A+FY AEV ALEY+
Sbjct: 96 LEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYI 155
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTL-------------CGTPDY 306
HS G+I+RD+KPEN+LL +GHIK+ DFG K + D T+ GT Y
Sbjct: 156 HSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAY 215
Query: 307 IAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD 366
+ PEV+++ P D W+ G +Y+ML+G +PF D++ ++ I+ ++FP F
Sbjct: 216 VPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEA 275
Query: 367 AQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGD 426
A+DLI +L+ + S+R G G +K HP+F+ V W KN+ + P + D
Sbjct: 276 ARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDW-----KNLRSQTPPKLAP---D 327
Query: 427 TSQYDRYPEEEVNYG 441
+ PE + +G
Sbjct: 328 PASQTASPERDDTHG 342
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 187 bits (476), Expect = 2e-47
Identities = 111/348 (31%), Positives = 170/348 (47%), Gaps = 50/348 (14%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ + L DF+ L+ +G G+FG V LV+ G YAM H E
Sbjct: 78 RLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAE 137
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
R++L ++++M+ +FQD L++IM+++ GG++ +LL K +FY AE
Sbjct: 138 RDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETV 197
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP------------------- 294
LA++ +H G I+RD+KP+N+LLD GH+KL+DFG +
Sbjct: 198 LAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDF 257
Query: 295 -------------------DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLA 335
+ ++ GTPDYIAPEV YNK DWWS GV++YEML
Sbjct: 258 TFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLI 317
Query: 336 GYTPFYDSNTIKTYENILN--APVRFPPF--FHSDAQDLISKLITRDLSQRLGNLQNGSE 391
GY PF +TY+ ++N + FPP A+DLI + + R+G G E
Sbjct: 318 GYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCC-EWEHRIG--APGVE 374
Query: 392 DVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQ-GDTSQYDRYPEEEV 438
++K++ +F V WE + E P I+ DTS +D +PE ++
Sbjct: 375 EIKSNSFFEGVDWEHIR----ERPAAISIEIKSIDDTSNFDEFPESDI 418
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 186 bits (472), Expect = 6e-47
Identities = 98/280 (35%), Positives = 158/280 (56%), Gaps = 7/280 (2%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
T +++L DF+I R LG G FGRV+L R + A+ E
Sbjct: 13 TEKQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREME 72
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+ + + HP I+R++G F D++++F+I++Y GGEL+ +L+++ A Y A + A
Sbjct: 73 IQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQA 132
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTK 315
L Y H K +I+RD+KPEN+LLD G +K+ DFG++ + T+CGT DY+APE+V +
Sbjct: 133 LAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQSSNKRKTMCGTLDYLAPEMVENR 192
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP--PFFHSDAQDLISK 373
++ +VD W+ G+L YE L G PF + T++ IL + FP P +A++LIS+
Sbjct: 193 DHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQ 252
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIE 413
L+ +D S+RL E + HPW + K +C +I+
Sbjct: 253 LLVKDPSKRL-----SIEKIMQHPWIVKNADPKGVCASID 287
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 186 bits (471), Expect = 8e-47
Identities = 110/361 (30%), Positives = 179/361 (49%), Gaps = 57/361 (15%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
+ +L DF ++ +G G+FG V LV+ G+ YAM H ER++L
Sbjct: 87 RLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLV 146
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
P+++ ++ FQDS L++IM+++ GG+L ++L F V +FY AE LA+
Sbjct: 147 ESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIAD 206
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGF----------AKYVPDVT----------- 297
+H G I+RD+KP+NIL+D++GHIKL+DFG A Y+ T
Sbjct: 207 VHRMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVD 266
Query: 298 -----------------------YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML 334
Y+ GTPDYIAPE+ + Y + DWWS G +++E L
Sbjct: 267 AIWLTMSSKDKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECL 326
Query: 335 AGYTPFYDSNTIKTYENILN--APVRFPPFFH--SDAQDLISKLITRDLSQRLGNLQNGS 390
G+ PF N+ +TY I+N + FP H +A+DL+ +L+T D RLG + G+
Sbjct: 327 IGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLMT-DSEHRLG--RGGA 383
Query: 391 EDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA----GQGDTSQYDRYPEEEVNYGIQGED 446
++ HP+F+ + W+ + + P+ P +++ + ++ PE+ V D
Sbjct: 384 IEIMQHPFFTGIDWDHI--RETAAPFIPNLKSITDTHYFPVDELEQVPEQPVTQQPASVD 441
Query: 447 P 447
P
Sbjct: 442 P 442
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 186 bits (471), Expect = 8e-47
Identities = 118/348 (33%), Positives = 174/348 (49%), Gaps = 63/348 (18%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F ++TLG G+FG V L YAM H ER++L+ + +
Sbjct: 668 FVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERDILAEADNEW 727
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
+++++ +FQD L+ +MDYI GG++ SLL + + FP +A+FY AE+ LA+E +H G
Sbjct: 728 VVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGF 787
Query: 265 IYRDLKPENILLDKNGHIKLTDFGF---------AKYVPD-------------------- 295
I+RD+KP+NIL+D +GHIKLTDFG +KY
Sbjct: 788 IHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSN 847
Query: 296 ---------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML 334
+ ++L GTP+YIAPEV+ K Y + DWWS GV+++EML
Sbjct: 848 CRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEML 907
Query: 335 AGYTPFYDSNTIKT------YENILNAPVRFPPFFHSDAQDLISKLITRDLSQRLGNLQN 388
G PF +T +EN L+ P + +A+DLI+KL RLG +N
Sbjct: 908 VGQPPFLAPTPTETQLKVINWENTLHIPAQVK--LSPEARDLITKLCC-SADHRLG--RN 962
Query: 389 GSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
G++D+K HP+FS + + + K PY P I DTS +D EE
Sbjct: 963 GADDLKAHPFFSAIDFSSDIRKQ-PAPYVPTISHPM-DTSNFDPVDEE 1008
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 183 bits (465), Expect = 4e-46
Identities = 99/256 (38%), Positives = 146/256 (56%), Gaps = 7/256 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+I + LG G FGRV+L + G A+ + E + S + H
Sbjct: 118 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 177
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+R++G F D +++++I+++ GEL+ LR+++RF VA Y ++ AL YLH K +
Sbjct: 178 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 237
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVP-DVTYTLCGTPDYIAPEVVSTKPYNKSVDW 323
I+RD+KPENILL +G IKL+DFG++ + P + TLCGT DY+ PE+V K + + VD
Sbjct: 238 IHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDL 297
Query: 324 WSFGVLIYEMLAGYTPFYD-SNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQR 382
WS GVL YE L G PF D S TY+ I ++ P F DA+DLIS+L+ + +R
Sbjct: 298 WSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEKR 357
Query: 383 LGNLQNGSEDVKNHPW 398
+ E V HPW
Sbjct: 358 M-----SLEQVMRHPW 368
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 182 bits (463), Expect = 7e-46
Identities = 109/305 (35%), Positives = 162/305 (52%), Gaps = 23/305 (7%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF++L+ +G G+FG V +VR G YAM +ER++L
Sbjct: 82 DFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRR 141
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKS-QRFPNPVAKFYAAEVCLALEYLHSK 262
+I + FQD + L+ +MDY GG++ +LL K P +AKFY AE+ LA++ LH
Sbjct: 142 WITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRL 201
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPD---VTYTLCGTPDYIAPEVVSTKP-- 316
G ++RD+KP+N+LLD GHI+L DFG + + D + GTPDYI+PE++
Sbjct: 202 GYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRAMEDG 261
Query: 317 ---YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAP--VRFPP-----FFHSD 366
Y K DWWS G+ +YEML G TPFY + TY I++ + FP +
Sbjct: 262 RGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWVVSEE 321
Query: 367 AQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGD 426
A+DLI +LI R G +NG D + HP+F + W + ++ PY P + + + D
Sbjct: 322 AKDLIRQLICSS-DVRFG--RNGLSDFQLHPFFEGIDWNTI--RDSNPPYVPEVSSPE-D 375
Query: 427 TSQYD 431
TS +D
Sbjct: 376 TSNFD 380
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 181 bits (459), Expect = 2e-45
Identities = 109/310 (35%), Positives = 167/310 (53%), Gaps = 22/310 (7%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF ++ +G G+FG V LVR + + YAM +ER++++ +
Sbjct: 86 DFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSE 145
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
+I+++ FQD++ L+M+MD++ GG++ SL+ P A FY EV LAL+ +H+ G
Sbjct: 146 WIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYD-IPEKWAIFYTMEVVLALDTIHNMG 204
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYV----PDVTYTLCGTPDYIAPEVVSTK---- 315
++RD+KP+N+LLD GH+KL DFG + V+ GTPDYI+PEV+ ++
Sbjct: 205 FVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDN 264
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN--APVRFPP--FFHSDAQDLI 371
Y + DWWS G+ +YEML G TPFY + + TY I++ + FPP A+ LI
Sbjct: 265 EYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALI 324
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQY- 430
+T D +QRLG + G ED+K HP+F W + P P + + DT +
Sbjct: 325 RAFLT-DRTQRLG--RYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPEL-SSDDDTRNFE 380
Query: 431 ----DRYPEE 436
D PEE
Sbjct: 381 DIERDEKPEE 390
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 179 bits (455), Expect = 6e-45
Identities = 111/325 (34%), Positives = 169/325 (51%), Gaps = 16/325 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSH- 202
DF + R +G G FG V+ R G+ YAM +ER MLS+VS
Sbjct: 190 DFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG 249
Query: 203 ---PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
PFI+ M FQ +L I+D + GG+L L + F FYA+EV L LE++
Sbjct: 250 QDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILGLEHM 309
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPDVTYTLCGTPDYIAPEVVST-KPY 317
H++ ++YRDLKP NILLD+NGH++++D G A Y + GT Y+APEV++ Y
Sbjct: 310 HNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHASVGTHGYMAPEVLAKGVAY 369
Query: 318 NKSVDWWSFGVLIYEMLAGYTPF-----YDSNTIKTYENILNAPVRFP-PFFHSDAQDLI 371
+ S DW+S G ++Y++L G++PF D N I + L + P D +DL+
Sbjct: 370 DSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEID--KMTLTQDIELPNEGLSKDCRDLL 427
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPI-QAGQGDTSQY 430
L+ RD+ RLG G +VK HP+F +V W+ + + + P PP + D
Sbjct: 428 EGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAADAFDI 487
Query: 431 DRYPEEEVNYGIQGEDPYHSIFTNF 455
+ ++EV G++ +D ++ NF
Sbjct: 488 GNFDDDEVK-GVKLQDGDSDLYKNF 511
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 179 bits (454), Expect = 8e-45
Identities = 107/324 (33%), Positives = 170/324 (52%), Gaps = 16/324 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSH- 202
DF + R +G G FG V+ R G+ YAM +ER MLS+VS
Sbjct: 190 DFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG 249
Query: 203 --PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
PFI+ M F +L I+D + GG+L L + F +FYAAE+ L LE++H
Sbjct: 250 DCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMH 309
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPDVTYTLCGTPDYIAPEVVST-KPYN 318
++ ++YRDLKP NILLD++GH++++D G A + + GT Y+APEV+ Y+
Sbjct: 310 NRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYD 369
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYE---NILNAPVRFPPFFHSDAQDLISKLI 375
S DW+S G +++++L G++PF T +E L V P F + L+ L+
Sbjct: 370 SSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELHSLLEGLL 429
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYP- 434
RD+++RLG L G+++VK P+F + W+ + + Y PP+ +G+ + D +
Sbjct: 430 QRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQR----YPPPLIPPRGEVNAADAFDI 485
Query: 435 ---EEEVNYGIQGEDPYHSIFTNF 455
+EE GI+ D ++ NF
Sbjct: 486 GSFDEEDTKGIKLLDSDQELYRNF 509
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 179 bits (454), Expect = 8e-45
Identities = 110/306 (35%), Positives = 162/306 (51%), Gaps = 24/306 (7%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF IL+ +G G+FG V +V+ + YAM +ER++L
Sbjct: 99 DFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQ 158
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCLALEYLHSK 262
+I + FQD+ L+++MDY GG+L +LL K + + P +AKFY E+ LA+ +H
Sbjct: 159 WITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQI 218
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPDVTY---TLCGTPDYIAPEVVSTKP-- 316
++RD+KP+N+LLDK GH++L DFG + D T GTPDYI+PE++
Sbjct: 219 RYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDG 278
Query: 317 ---YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTY------ENILNAPVRFPPFF--HS 365
Y DWWS GV +YEML G TPFY + ++TY +N N P + +
Sbjct: 279 KGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSE 338
Query: 366 DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG 425
+QDL+ KLI RLG QNG +D +HPWF + W+ + + PY P + +
Sbjct: 339 TSQDLLCKLICIP-ENRLG--QNGIQDFMDHPWFVGIDWKNI--RQGPAPYVPEV-SSPT 392
Query: 426 DTSQYD 431
DTS +D
Sbjct: 393 DTSNFD 398
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 178 bits (452), Expect = 1e-44
Identities = 98/280 (35%), Positives = 152/280 (54%), Gaps = 8/280 (2%)
Query: 130 TLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEH 189
T+ GK+ + DF+I R LG G FG V+L R+ G F+ EH
Sbjct: 15 TVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTK-TGHFHVAIKVLFKSQLISGGVEH 73
Query: 190 TND-ERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFY 248
+ E + S ++HP II+++ F D+++++++++Y GGE++ L S+RF P A Y
Sbjct: 74 QLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKY 133
Query: 249 AAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP-DVTYTLCGTPDYI 307
E+ AL Y H K +I+RD+KPEN+L+ G +K+ DFG++ + P + T+CGT DY+
Sbjct: 134 MYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYL 193
Query: 308 APEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDA 367
PE+V+ ++ +VD W+ GVL YE L G PF + KTY I A +P A
Sbjct: 194 PPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGA 253
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKL 407
+DLI +L+ D R E VK H W ++ K+
Sbjct: 254 RDLIGRLLVVDPKARC-----TLEQVKEHYWIQGMMEAKI 288
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 177 bits (449), Expect = 3e-44
Identities = 112/341 (32%), Positives = 167/341 (48%), Gaps = 59/341 (17%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F ++TLG G+FG V L R YA H ER++L+ + +
Sbjct: 705 FVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEW 764
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++R++ +FQD L+ +MDYI GG++ SLL + FP +A+FY AE+ A+E +H G
Sbjct: 765 VVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGF 824
Query: 265 IYRDLKPENILLDKNGHIKLTDFGF---------AKYVPD-------------------- 295
I+RD+KP+NIL+D++GHIKLTDFG +KY
Sbjct: 825 IHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSS 884
Query: 296 ---------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML 334
+ ++L GTP+YIAPEV+ Y + DWWS GV+++EML
Sbjct: 885 CRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEML 944
Query: 335 AGYTPFYDSNTIKTYENILN--APVRFPP--FFHSDAQDLISKLITRDLSQRLGNLQNGS 390
G PF ++T ++N + PP +A DLI KL R RLG +NG+
Sbjct: 945 VGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKL-CRGPEDRLG--KNGA 1001
Query: 391 EDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
+++K HP+F + + L + Y P I DTS +D
Sbjct: 1002 DEIKAHPFFKTIDFSSDL-RQQSASYIPKI-THPTDTSNFD 1040
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 176 bits (447), Expect = 5e-44
Identities = 95/269 (35%), Positives = 152/269 (56%), Gaps = 9/269 (3%)
Query: 141 ALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
+L DF++ + LG G FG+V+ VR G A+ + E + + +
Sbjct: 100 SLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSL 159
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
+HP + + +G F D ++++++M+Y+ GE++ LLR F + +A Y ++ AL+Y+H
Sbjct: 160 NHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMH 219
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYN 318
K II+RD+KPENIL+ N IKLTDFG++ P + T+CGT DY++PE+V ++ Y+
Sbjct: 220 KKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYD 279
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
++D W+ GVL +E+L G PF + TY+ I ++ P DAQDLI KL+ D
Sbjct: 280 HTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYD 339
Query: 379 LSQRLGNLQNGSEDVKNHPWF--SEVVWE 405
R+ DVK HPW ++ WE
Sbjct: 340 PKDRM-----RLGDVKMHPWILRNKPFWE 363
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 175 bits (444), Expect = 1e-43
Identities = 97/277 (35%), Positives = 148/277 (53%), Gaps = 6/277 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
++AL DF+I R LG G FG V+L R + A+ E + S
Sbjct: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
+ HP I+R++G F D+ ++++I++Y G ++ L+K +F Y E+ AL Y
Sbjct: 187 HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSY 246
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-TYTLCGTPDYIAPEVVSTKPY 317
HSK +I+RD+KPEN+LL G +K+ DFG++ + P TLCGT DY+ PE++ + +
Sbjct: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMH 306
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
++ VD WS GVL YE L G PF + +TY+ I FP F A+DLIS+L+
Sbjct: 307 DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKH 366
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIET 414
+ SQR +V HPW + + C+N E+
Sbjct: 367 NPSQR-----PMLREVLEHPWITANSSKPSNCQNKES 398
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 175 bits (444), Expect = 1e-43
Identities = 103/307 (33%), Positives = 160/307 (51%), Gaps = 17/307 (5%)
Query: 137 SGKYA--LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDER 194
SGK A L F ++R++G G+FG+V +V+ +++A+ + E
Sbjct: 18 SGKSAPCLQHFSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRCIEKGVAANVIREL 77
Query: 195 NMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCL 254
+LS +SHPFI+ +W TFQD ++M+ D + GG+L L + +F AK Y E+CL
Sbjct: 78 TLLSKMSHPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRAKLYLCEICL 137
Query: 255 ALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVV 312
A+EYLH I++RD+KPENILLD+ GH LTD A + D + + GT Y+APE+
Sbjct: 138 AVEYLHEMKIVHRDIKPENILLDEQGHAHLTDLNLATQLEDDQLATSYSGTRPYMAPEIY 197
Query: 313 ST-----KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIK---TYENILNAPVRFPPFFH 364
+T Y+ VDWW+ GV YEML G TPF S+ K Y + + +P +
Sbjct: 198 ATYLEIEDGYDSRVDWWALGVCFYEMLRGRTPFEFSSRTKPEEAYVAFRESSIPYPAHWP 257
Query: 365 SDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQ 424
+D I+ ++ D +RL G E +K H + + ++ + K +P P + G
Sbjct: 258 TDLIQFINSMLKFDKEKRL----VGLEAIKKHSYTERIDFKSVFEKK-PSPVFIPCKEGL 312
Query: 425 GDTSQYD 431
Y+
Sbjct: 313 NCDPMYE 319
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 175 bits (444), Expect = 1e-43
Identities = 96/262 (36%), Positives = 141/262 (53%), Gaps = 8/262 (3%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
+ L +F I R LG G FG V+L R + A+ E + S
Sbjct: 149 WELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSH 208
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLALE 257
+ HP I+R++ F D ++++I++Y G LF+ L+ +RF + Y +C AL
Sbjct: 209 LRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALL 268
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD-VTYTLCGTPDYIAPEVVSTKP 316
YLH + II+RD+KPEN+LL G +K+ DFG++ + P+ + TLCGT DY+ PE+V KP
Sbjct: 269 YLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEPNSMRMTLCGTVDYLPPEMVQGKP 328
Query: 317 YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLIT 376
+ K+VD WS GVL +E+L G+ PFY N +TY+ IL + P A LISKL+
Sbjct: 329 HTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLV 388
Query: 377 RDLSQRLGNLQNGSEDVKNHPW 398
+ RL + V HPW
Sbjct: 389 LNPQHRL-----PLDQVMVHPW 405
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 175 bits (444), Expect = 1e-43
Identities = 109/310 (35%), Positives = 162/310 (52%), Gaps = 35/310 (11%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF I +G G FG VHLV YAM E ER+++SI +
Sbjct: 112 DFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQVKE----ERDIMSIRNSE 167
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
++I + FQD+ L+++M+Y+ GG+L SL+ + F +A+FY AE+ +AL LH G
Sbjct: 168 WLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMG 227
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTL----CGTPDYIAPEVVST----- 314
++RD+KPENIL+D+ GHIKL DFG A + + L GTPDYIAPE++ T
Sbjct: 228 YVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYK 287
Query: 315 ---KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN--------APVRFPPFF 363
++ S D+WS G++ YE++ TPF++ N +TY IL+ + FP
Sbjct: 288 LSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADL 347
Query: 364 HSDA--QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQ 421
++LI L+T S+RL E +KNHP+FSE+ W + + P P
Sbjct: 348 KVSVNYRNLIESLVTNP-SKRL-----SYERIKNHPFFSEIPWGSI---RSQVPPIIPTV 398
Query: 422 AGQGDTSQYD 431
DTS ++
Sbjct: 399 RSDDDTSNFE 408
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 174 bits (442), Expect = 2e-43
Identities = 107/324 (33%), Positives = 168/324 (51%), Gaps = 16/324 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSH- 202
+F + R +G G FG V+ R G+ YAM +ER MLS+VS
Sbjct: 190 EFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG 249
Query: 203 --PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
PFI+ M F +L I+D + GG+L L + F +FYA E+ L LE++H
Sbjct: 250 DCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHVH 309
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPDVTYTLCGTPDYIAPEVVST-KPYN 318
++ ++YRDLKP NILLD++GH +++D G A + + GT Y+APEV+ Y+
Sbjct: 310 NRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYD 369
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYE---NILNAPVRFPPFFHSDAQDLISKLI 375
S DW+S G +++++L G++PF T +E L V P F + + L+ L+
Sbjct: 370 SSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEGLL 429
Query: 376 TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYP- 434
RD+S+RLG GS++VK H +F V W+ + + Y PP+ +G+ + D +
Sbjct: 430 QRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQK----YPPPLIPPRGEVNAADAFDI 485
Query: 435 ---EEEVNYGIQGEDPYHSIFTNF 455
+EE GI+ D ++ NF
Sbjct: 486 GSFDEEDTKGIKLLDCDQELYKNF 509
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 174 bits (441), Expect = 2e-43
Identities = 93/272 (34%), Positives = 144/272 (52%), Gaps = 7/272 (2%)
Query: 129 STLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXE 188
S A ++ L DF I + LG G FG V+L R + A+
Sbjct: 15 SDASAAAAQKRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEH 74
Query: 189 HTNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFY 248
E + S + HP I+R++G F D +++++I++Y GEL+ L+K + F A Y
Sbjct: 75 QLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATY 134
Query: 249 AAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIA 308
A + AL Y H K +I+RD+KPEN+L+ G +K+ DFG++ + + T+CGT DY+
Sbjct: 135 VASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLP 194
Query: 309 PEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP--PFFHSD 366
PE+V + ++ SVD WS G+L YE L G PF TY I+ ++FP P +
Sbjct: 195 PEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISAS 254
Query: 367 AQDLISKLITRDLSQRLGNLQNGSEDVKNHPW 398
A+DLIS+++ ++ SQRL + HPW
Sbjct: 255 AKDLISQMLVKESSQRL-----PLHKLLEHPW 281
>At3g14370 [R] KOG0610 Putative serine/threonine protein kinase
Length = 480
Score = 174 bits (440), Expect = 3e-43
Identities = 107/339 (31%), Positives = 163/339 (47%), Gaps = 62/339 (18%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
+ G L +++R LGTG+ GRV L + +A+ E
Sbjct: 79 SDGNIHLRHLKLIRHLGTGNLGRVFLCNLRDSSARFALKVIDRNCLTTEKKLSQVETEAE 138
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVC 253
+LS++ HPF+ ++ +S +++DY G+L SLLRK R P +F+AAEV
Sbjct: 139 ILSLLDHPFLPTLYARIDESHYTCLLIDYAPNGDLHSLLRKQPGNRLPIQPVRFFAAEVL 198
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGF------------------------ 289
+ALEYLH+ GI+YRDLKPEN+LL ++GH+ L+DF
Sbjct: 199 VALEYLHAMGIVYRDLKPENVLLREDGHVMLSDFDLCFKSDVVPTFKSRRYRRSSSSPSL 258
Query: 290 --------------------------AKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDW 323
A+ V + + GT +Y+APE+VS + VDW
Sbjct: 259 RRRRSGCFSVAAEKKYEREEIVSEFAAEPVTAFSRSCVGTHEYLAPELVSGNGHGSGVDW 318
Query: 324 WSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD-----AQDLISKLITRD 378
W+FG+ +YE+L G TPF + +T NI++ FH D A+DLI KL+ +D
Sbjct: 319 WAFGIFLYELLYGTTPFKGESKEQTLRNIVSTTK--TASFHMDGDLDEARDLIEKLLVKD 376
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYE 417
+RLG G++D+K HP+F + W L ++ + P E
Sbjct: 377 PRKRLG-CARGAQDIKRHPFFDGIKWP--LIRHYKPPEE 412
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 173 bits (438), Expect = 5e-43
Identities = 94/306 (30%), Positives = 166/306 (53%), Gaps = 23/306 (7%)
Query: 142 LYD-FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXX-EHTNDERNMLSI 199
L+D + I R LGTG+F +V+ G A+ E E ++ +
Sbjct: 11 LFDKYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRL 70
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
+ HP ++ + +++F +M+Y+ GGELF ++ + + P +A+ Y ++ A+++
Sbjct: 71 LRHPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFC 130
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV------------PDVTYTLCGTPDYI 307
HS+G+ +RD+KPEN+LLD G +K+TDFG + + D+ +T CGTP Y+
Sbjct: 131 HSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYV 190
Query: 308 APEVVSTKPYNKSV-DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD 366
APEV+ K Y+ ++ D WS G+++Y +LAG+ PF D N + Y I A FPP+F +
Sbjct: 191 APEVLRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLE 250
Query: 367 AQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKL---LCKNIETPYEPPIQAG 423
+++L+S+L+ D QR+ ++K PWF + + + + I +P EPP +
Sbjct: 251 SKELLSRLLVPDPEQRI-----SMSEIKMIPWFRKNFTPSVAFSIDETIPSPPEPPTKKK 305
Query: 424 QGDTSQ 429
+ D ++
Sbjct: 306 KKDLNE 311
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 172 bits (437), Expect = 7e-43
Identities = 90/262 (34%), Positives = 143/262 (54%), Gaps = 7/262 (2%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
++ DF I + LG G FG V+L R + A+ E + S
Sbjct: 13 RWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQS 72
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEY 258
+ HP I+R++G F D +++++I++Y GEL+ L+K + F A Y A + AL Y
Sbjct: 73 HLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALIY 132
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYN 318
H K +I+RD+KPEN+L+ G +K+ DFG++ + + T+CGT DY+ PE+V + ++
Sbjct: 133 CHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLPPEMVESVEHD 192
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP--PFFHSDAQDLISKLIT 376
SVD WS G+L YE L G PF +TY+ I+ ++FP P S A+DLIS+++
Sbjct: 193 ASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAKDLISQMLV 252
Query: 377 RDLSQRLGNLQNGSEDVKNHPW 398
++ +QRL + HPW
Sbjct: 253 KESTQRL-----ALHKLLEHPW 269
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 172 bits (436), Expect = 9e-43
Identities = 106/306 (34%), Positives = 163/306 (52%), Gaps = 25/306 (8%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+IL+ +G G+F V +V+ G+ YAM +ER++L
Sbjct: 70 DFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRR 129
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRK-SQRFPNPVAKFYAAEVCLALEYLHSK 262
+I ++ FQD L+++M+Y GG+L +LL K +R P +A+FY AE+ +A++ +H
Sbjct: 130 WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRL 189
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPDVT---YTLCGTPDYIAPEVV------ 312
G ++RD+KP+NILLD+ GHI+L DFG K D T GTPDY++PE++
Sbjct: 190 GYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGG 249
Query: 313 -STKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENI------LNAPVRFPPFFHS 365
T Y DWW+ GV YEM G TPFY +T +TY I L+ P+
Sbjct: 250 PGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPL-VDEGVPE 308
Query: 366 DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG 425
+A+D I +L+ RLG + G+ D + HP+F + W+ L ++ P+ P + G
Sbjct: 309 EARDFIQRLLCPP-ETRLG--RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFE-GAT 362
Query: 426 DTSQYD 431
DT +D
Sbjct: 363 DTCNFD 368
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 172 bits (435), Expect = 1e-42
Identities = 92/256 (35%), Positives = 139/256 (53%), Gaps = 6/256 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+I R LG G FG V+L R + A+ E + + + HP
Sbjct: 8 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 67
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I+R++ F D++++++I++Y GEL+ L+KS++ EV AL Y H K
Sbjct: 68 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHDKK 127
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVP-DVTYTLCGTPDYIAPEVVSTKPYNKSVD 322
+I+RD+KPEN+LL G +K+ DFG++ + P T+CGT DY+ PE++ + Y++ VD
Sbjct: 128 VIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKTMCGTLDYLPPEMIEGRTYDEKVD 187
Query: 323 WWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQR 382
W GVL YE+L GY PF ++ +TY IL VRFP A+DLIS+L+ +R
Sbjct: 188 LWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLER 247
Query: 383 LGNLQNGSEDVKNHPW 398
L Q + HPW
Sbjct: 248 LPLAQ-----ILKHPW 258
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 172 bits (435), Expect = 1e-42
Identities = 101/286 (35%), Positives = 152/286 (52%), Gaps = 8/286 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ R LG G FG V + G+ YA +E+ +L V+ F
Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRF 245
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGEL-FSLLRKSQR-FPNPVAKFYAAEVCLALEYLHSK 262
++ + ++ L +++ + GG+L F + Q FP A FYAAE+C LE LH +
Sbjct: 246 VVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRE 305
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYNKS 320
I+YRDLKPENILLD +GHI+++D G A +VP+ GT Y+APEVV + Y S
Sbjct: 306 RIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFS 365
Query: 321 VDWWSFGVLIYEMLAGYTPFYD-SNTIKTYE---NILNAPVRFPPFFHSDAQDLISKLIT 376
DWW+ G L+YEM+AG +PF IK E + P + F A+ L S+L+
Sbjct: 366 PDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLC 425
Query: 377 RDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
+D ++RLG + +VK HP F ++ +++L +E P++P QA
Sbjct: 426 KDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQA 471
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 171 bits (434), Expect = 2e-42
Identities = 92/260 (35%), Positives = 142/260 (54%), Gaps = 6/260 (2%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
+ + DF+I R LG G FG V+L R + A+ E + +
Sbjct: 72 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
+ HP I+R++ F D +++++I++Y GEL+ L+KS F E+ AL Y
Sbjct: 132 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC 191
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY-TLCGTPDYIAPEVVSTKPYN 318
H K +I+RD+KPEN+LL G +K+ DFG++ + P + T+CGT DY+ PE++ + +N
Sbjct: 192 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN 251
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+ VD W GVL YE+L G PF ++ +TY I+ ++FP + AQDLISKL+ +
Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311
Query: 379 LSQRLGNLQNGSEDVKNHPW 398
S+RL Q V HPW
Sbjct: 312 PSERLPLAQ-----VSAHPW 326
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 171 bits (432), Expect = 3e-42
Identities = 88/277 (31%), Positives = 154/277 (54%), Gaps = 9/277 (3%)
Query: 129 STLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXE 188
ST + G+ + +++ RTLG G+F +V R+ NG A+
Sbjct: 15 STPSGSSSGGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIA 74
Query: 189 HTNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFY 248
E + + ++ HP +IRM+ +++ +++++ GGELF + + R A+ Y
Sbjct: 75 QIKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKY 134
Query: 249 AAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFA---KYVPDVTYTLCGTPD 305
++ A++Y HS+G+ +RDLKPEN+LLD NG +K++DFG + + + +T CGTP+
Sbjct: 135 FQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQQEDGLLHTTCGTPN 194
Query: 306 YIAPEVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFH 364
Y+APEV++ K Y+ D WS GV+++ ++AGY PF DSN Y+ I A PP+F
Sbjct: 195 YVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFS 254
Query: 365 SDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
+ A+ LI +++ + + R+ +E ++N WF +
Sbjct: 255 ASAKKLIKRILDPNPATRI----TFAEVIENE-WFKK 286
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 171 bits (432), Expect = 3e-42
Identities = 112/348 (32%), Positives = 175/348 (50%), Gaps = 64/348 (18%)
Query: 145 FQILRTLGTGSFGRVHLVR----SNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
F L+ +G G+FG V LV SNH YAM H ER++L+
Sbjct: 719 FVKLKPIGVGAFGEVTLVSKIDTSNH---LYAMKTLRKADVLKRNQVAHVKAERDILAEA 775
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
+ ++++++ +FQD L+ +MDYI GG+L SLL K F +A+FY AEV A++ +H
Sbjct: 776 DNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVH 835
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGF---------AKYVPD---------------- 295
G I+RD+KP+NIL+D++GHIKLTDFG +KY +
Sbjct: 836 KMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEY 895
Query: 296 ---------------------VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML 334
+ ++L GTP+YIAPEV+ Y + D+WS GV++YEML
Sbjct: 896 SENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEML 955
Query: 335 AGYTPFYDSNTIKTYENILN--APVRFPP--FFHSDAQDLISKLITRDLSQRLGNLQNGS 390
G PF ++ ++T + ++N + PP +A DLI +L +RLG
Sbjct: 956 VGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATDLIRRLCA-SADKRLG---KSV 1011
Query: 391 EDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEV 438
++VK+H +F + + + + + PY P I+ DTS +D E++
Sbjct: 1012 DEVKSHDFFKGIDFADM--RKQKAPYIPEIK-HPTDTSNFDPVDPEKL 1056
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 170 bits (431), Expect = 4e-42
Identities = 94/285 (32%), Positives = 155/285 (53%), Gaps = 16/285 (5%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
FQILR +G GSFG+V +V+ + YAM + E ++ + HPF
Sbjct: 23 FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPF 82
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++ +W +FQD + +FM++D + GG+L L+++ F K Y E+ LALEYL I
Sbjct: 83 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHI 142
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYV--PDVTYTLCGTPDYIAPEVVST-----KPY 317
I+RD+KP+NILLD++GH+ +TDF A V + ++ GT Y+APEV Y
Sbjct: 143 IHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGY 202
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILN----APVRFPPFFHSDAQDLISK 373
+ VDWWS G+ YE+L G+ P Y+ +++ + ILN V + + L+ K
Sbjct: 203 SYPVDWWSLGITAYELLRGWRP-YEIHSVTPIDEILNMFKVERVHYSSTWCKGMVALLRK 261
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP 418
L+T+D R+ +L D+++ P+ +++ W+ + K + + P
Sbjct: 262 LLTKDPESRVSSL----HDIQSVPYLADMNWDAVFKKALMPGFVP 302
>At1g53700 [R] KOG0610 Putative serine/threonine protein kinase
Length = 476
Score = 169 bits (429), Expect = 6e-42
Identities = 116/339 (34%), Positives = 169/339 (49%), Gaps = 63/339 (18%)
Query: 136 TSGKYALYDFQILRTLGTGSFGRVHL--VRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
+ G+ L F+++R LGTG+ GRV L +R N +A+ H E
Sbjct: 84 SDGRLHLRHFKLVRHLGTGNLGRVFLCHLRDCPNPTGFALKVIDRDVLTAKKIS-HVETE 142
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRK--SQRFPNPVAKFYAAE 251
+LS++ HPF+ ++ S +++DY G+L SLLRK + R P +F+AAE
Sbjct: 143 AEILSLLDHPFLPTLYARIDASHYTCLLIDYCPNGDLHSLLRKQPNNRLPISPVRFFAAE 202
Query: 252 VCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGF---AKYVP-------------- 294
V +ALEYLH+ GI+YRDLKPENIL+ ++GHI L+DF A VP
Sbjct: 203 VLVALEYLHALGIVYRDLKPENILIREDGHIMLSDFDLCFKADVVPTFRSRRFRRTSSSP 262
Query: 295 ------------DVTY-------------------TLCGTPDYIAPEVVSTKPYNKSVDW 323
+V Y + GT +Y+APE+V+ + VDW
Sbjct: 263 RKTRRGGGCFSTEVEYEREEIVAEFAAEPVTAFSKSCVGTHEYLAPELVAGNGHGSGVDW 322
Query: 324 WSFGVLIYEMLAGYTPFYDSNTIKTYENIL-NAPVRFPPFFHS--DAQDLISKLITRDLS 380
W+FG+ +YEML G TPF +T NI+ N V F +A+DLI KL+ +D
Sbjct: 323 WAFGIFLYEMLYGTTPFKGGTKEQTLRNIVSNDDVAFTLEEEGMVEAKDLIEKLLVKDPR 382
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPP 419
+RLG G++D+K H +F + W L +N Y+PP
Sbjct: 383 KRLG-CARGAQDIKRHEFFEGIKWP--LIRN----YKPP 414
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 169 bits (428), Expect = 8e-42
Identities = 91/266 (34%), Positives = 143/266 (53%), Gaps = 8/266 (3%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
++L DF + R LG G FG V + R R A+ E +
Sbjct: 39 WSLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYH 98
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLALE 257
+ HP I+ ++G F D +++F+I+DY GELF++L+ + +A + ++ AL
Sbjct: 99 LRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALH 158
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP-DVTYTLCGTPDYIAPEVVSTKP 316
Y HSKG+I+RD+KPEN+LLD ++KL DFG++ +TLCGT DY+APE+VS +P
Sbjct: 159 YCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHSKRHTLCGTMDYLAPEMVSNQP 218
Query: 317 YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLIT 376
++ +VD W+ G+L++EML GY PF + K I + P A LI+ +I
Sbjct: 219 HDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDGAASLINAIIK 278
Query: 377 RDLSQRLGNLQNGSEDVKNHPWFSEV 402
++ +RL + D+ HPW E+
Sbjct: 279 KEPQERLPLV-----DIMAHPWIKEM 299
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 168 bits (426), Expect = 1e-41
Identities = 95/275 (34%), Positives = 144/275 (51%), Gaps = 6/275 (2%)
Query: 141 ALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
AL DF+I R LG G FG V+L R + A+ E + S +
Sbjct: 128 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 187
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
HP I+R++G F D+ ++++I++Y G ++ L+K +F + AL Y H
Sbjct: 188 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANALSYCH 247
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-TYTLCGTPDYIAPEVVSTKPYNK 319
SK +I+RD+KPEN+LL G +K+ DFG++ + P TLCGT DY+ PE++ + +++
Sbjct: 248 SKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDE 307
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
VD WS GVL YE L G PF + +TY+ I FP F A+DLIS+L+ +
Sbjct: 308 KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNP 367
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIET 414
SQR +V HPW + + C+N E+
Sbjct: 368 SQR-----PMLREVLEHPWITANSSKPSNCQNKES 397
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 168 bits (425), Expect = 2e-41
Identities = 92/279 (32%), Positives = 153/279 (53%), Gaps = 21/279 (7%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ R LG G+FG+V+ + G A+ E E +++ +V HP
Sbjct: 15 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVRHPN 74
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+ + ++F IM+Y++GGELFS + K + A+ Y ++ A+++ HS+G+
Sbjct: 75 IVELKEVMATKTKIFFIMEYVKGGELFSKIVKG-KLKEDSARKYFQQLISAVDFCHSRGV 133
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT-----YTLCGTPDYIAPEVVSTKPYNK 319
+RDLKPEN+L+D+NG +K++DFG + + +T CGTP Y+APEV+ K Y+
Sbjct: 134 SHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYDG 193
Query: 320 SV-DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+ D WS G+++Y +LAG+ PF D N +K Y I + +PP+F +++ LISKL+ D
Sbjct: 194 AKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPWFSPESKRLISKLLVVD 253
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYE 417
++R+ + PWF KNI +P E
Sbjct: 254 PNKRI-----SIPAIMRTPWFR---------KNINSPIE 278
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 167 bits (424), Expect = 2e-41
Identities = 94/283 (33%), Positives = 154/283 (54%), Gaps = 43/283 (15%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXX-------------- 187
L+DF+ +R LG G++G+V LV+ + + YAM
Sbjct: 125 LHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGN 184
Query: 188 ------------EHTNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLR 235
E T ER++LS + HP I++++ +F D+ +L++++ YI GGELF L+
Sbjct: 185 NNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLK 244
Query: 236 KSQRFPNPVAKFYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP- 294
+ FYAAE+ AL +LH+KG++YRDLKPEN LL++ GH+ LTDFG +K
Sbjct: 245 EHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSAN 304
Query: 295 ------------DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYD 342
+ Y++ GTP+Y APE++ K Y+++ DW+S G L+Y+ML G P+
Sbjct: 305 DSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTG 364
Query: 343 SNTIKTYENILNAPVRFP--PFFHSDA-QDLISKLITRDLSQR 382
SN K N + + P PF+ S+ +D+++ L+ ++ ++R
Sbjct: 365 SNH-KVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKR 406
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 167 bits (422), Expect = 4e-41
Identities = 111/357 (31%), Positives = 169/357 (47%), Gaps = 71/357 (19%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DFQ + +G G +G V L R A+ H ER++L+ +
Sbjct: 207 DFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLTERDILTTANSE 266
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
+++R+ FQD+ +++ M+++ GG+ +LL S + AKFYA E+ LA++ LH G
Sbjct: 267 WLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFLAIDALHQLG 326
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYV------------------------------ 293
I+RDLKPEN L+ +GHIKLTDFG + +
Sbjct: 327 YIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIESMKIRLQEVNNVVVPERSMRERR 386
Query: 294 ----------PDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDS 343
P +++ G+PDY+APEV+ + YN SVD+WS G ++YE L+G+ PF S
Sbjct: 387 QVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNHSVDYWSLGCIMYECLSGFPPFSGS 446
Query: 344 NTIKTYENILNAPVRF--PPF---------FHSDAQDLISKLITRDLSQRLGNLQNGSED 392
N +T+ N+ N F P + + DA D + IT D R +L +
Sbjct: 447 NVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAWDFVCHCIT-DPKDRFCSL----KQ 501
Query: 393 VKNHPWFSEVVWEKLLCKNIETPYEPP--------IQAGQGD--TSQYDRYPEEEVN 439
V HP+FS++ W KN+ T Y PP I AG D T++ D +EV+
Sbjct: 502 VMQHPYFSKIDW-----KNVRTAYRPPFVPDLNSEIDAGYFDDFTNENDMSKYKEVH 553
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 165 bits (417), Expect = 1e-40
Identities = 86/263 (32%), Positives = 145/263 (54%), Gaps = 12/263 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ R LG G+F +V+ R+ G+ AM + E +++ +V HP
Sbjct: 24 YELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPN 83
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+ + +++ M+ + GGELF+ + K R VA+ Y ++ A+++ HS+G+
Sbjct: 84 IVELHEVMASKSKIYFAMELVRGGELFAKVAKG-RLREDVARVYFQQLISAVDFCHSRGV 142
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYV-----PDVTYTLCGTPDYIAPEVVSTKPYN- 318
+RDLKPEN+LLD+ G++K+TDFG + + + +T CGTP Y+APEV+ K Y+
Sbjct: 143 YHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDG 202
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
D WS GV+++ +LAGY PF D N + Y I + P + SDA+ L++KL+ +
Sbjct: 203 AKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRLVTKLLDPN 262
Query: 379 LSQRLGNLQNGSEDVKNHPWFSE 401
+ R+ E V + PWF +
Sbjct: 263 PNTRI-----TIEKVMDSPWFKK 280
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 164 bits (415), Expect = 3e-40
Identities = 94/283 (33%), Positives = 149/283 (52%), Gaps = 21/283 (7%)
Query: 151 LGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN-MLSIVSHPFIIRMW 209
+G GSF +V + + YA+ ++ N ER+ M+ + P I R++
Sbjct: 60 IGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGFPGISRLF 119
Query: 210 GTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIYRDL 269
TFQD +L+ +++ GEL ++K + +FYAAE+ ++EY+HS GII+RDL
Sbjct: 120 HTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSCGIIHRDL 179
Query: 270 KPENILLDKNGHIKLTDFGFA-----KYVPDVTYT-----LCGTPDYIAPEVVSTKPYNK 319
KPENIL D N H+K+TDFG A KYV YT GT +Y+APE++S + +K
Sbjct: 180 KPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELLSRQVVSK 239
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
S D W+F ++Y+M+ G PF+ SN ++ I++ P D L S L
Sbjct: 240 SSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPKLLPPDIVPLFSHLFRIQP 299
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
S R + ++ +K P+F+ + W+ N+ T PP+Q+
Sbjct: 300 SDR-----STTQQIKQFPFFATITWD-----NLWTQDPPPMQS 332
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 164 bits (415), Expect = 3e-40
Identities = 87/293 (29%), Positives = 154/293 (51%), Gaps = 24/293 (8%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ RT+G G+F +V R++ G A+ E E + ++ HP
Sbjct: 14 YEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPN 73
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
+++++ ++F+I++Y+ GGELF + R A+ Y ++ A++Y HS+G+
Sbjct: 74 VVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRGV 133
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-----TYTLCGTPDYIAPEVVSTKPYN- 318
+RDLKPEN+LLD G++K++DFG + V +T CGTP+Y+APEV++ + Y+
Sbjct: 134 YHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYDG 193
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+ D WS GV++Y +LAGY PF DSN + Y+ I + PP+ A LI++++ +
Sbjct: 194 ATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFNCPPWLSLGAMKLITRILDPN 253
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
R+ ++V WF + Y+PP+ + D++ D
Sbjct: 254 PMTRV-----TPQEVFEDEWFKK-------------DYKPPVFEERDDSNMDD 288
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 163 bits (412), Expect = 6e-40
Identities = 88/280 (31%), Positives = 154/280 (54%), Gaps = 12/280 (4%)
Query: 128 TSTLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXX 187
TS K R + L +++ + LG G+F +V+L R+ A+
Sbjct: 9 TSLPKERSSPQALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLI 68
Query: 188 EHTNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKF 247
H E ++L V HP I++++ +++ +M+Y+ GGELF+ + K R VA+
Sbjct: 69 AHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKG-RLKEEVARK 127
Query: 248 YAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT-----YTLCG 302
Y ++ A+ + H++G+ +RDLKPEN+LLD+NG++K++DFG + + +T CG
Sbjct: 128 YFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCG 187
Query: 303 TPDYIAPEVVSTKPYNKS-VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPP 361
TP Y+APEV++ K Y+ + VD WS GV+++ ++AGY PF+D N + Y+ I R P
Sbjct: 188 TPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPR 247
Query: 362 FFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
+F ++ L+SKL+ + +R ++ + WF +
Sbjct: 248 WFSTELTRLLSKLLETNPEKRF-----TFPEIMENSWFKK 282
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 162 bits (411), Expect = 7e-40
Identities = 94/283 (33%), Positives = 145/283 (51%), Gaps = 23/283 (8%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS-H 202
DF+ LG GS+ V N R YA+ ++ N E+ L I+S H
Sbjct: 98 DFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKH 157
Query: 203 PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 262
P I+++ TFQD+ L+ ++ GEL + K RF A++YAA + +++Y+H +
Sbjct: 158 PGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGR 217
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-----------------TYTLCGTPD 305
G+I+RDLKPENILLD N K+TDFG AK + + + GT
Sbjct: 218 GVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTAR 277
Query: 306 YIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHS 365
Y++PEV+S K + D W+FG ++++MLAG PF N T+++IL+ PP
Sbjct: 278 YVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPDISD 337
Query: 366 DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLL 408
A DLI KL+ D RL +++ HP+F+ + ++ L
Sbjct: 338 VASDLIKKLLVLDPKDRL-----TVDEIHQHPFFNGIKFDNTL 375
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 162 bits (411), Expect = 7e-40
Identities = 100/305 (32%), Positives = 154/305 (49%), Gaps = 22/305 (7%)
Query: 135 VTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDER 194
V K D++I++ + G +G V LVR + YAM E+
Sbjct: 35 VVEAKTKPSDYEIVKNVAKGGYGEVFLVRRE---KIYAMKRVSKELVLKQPHTALFMAEK 91
Query: 195 N-MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
M+ + +++ T QD + L+ +MD+I GG+ LL K +FYAAE+
Sbjct: 92 EAMVDCIGSEWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEEDWVRFYAAEIV 151
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPE 310
AL+ LH G I+RDLKP+N+L+ +GH+KL DFG + D + GTPDY++P+
Sbjct: 152 AALDELHKLGWIHRDLKPDNVLIGIDGHVKLADFGSCIKMKDGKARSSITVGTPDYVSPD 211
Query: 311 VVSTK----PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD 366
V+ + Y + VD+W+ GV+IYEM+ G TPFY ++TY I FP +
Sbjct: 212 VLCSVNEECEYGEDVDFWTLGVIIYEMIYGTTPFYSDTLMETYRRITRVEFGFPFKVSPE 271
Query: 367 AQDLISKLI-TRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG 425
LI LI +D R+ E++K+H +F V W +L K ++ P+ P + G
Sbjct: 272 LTSLIEGLIAAKDRRMRI-------EEIKSHAFFEGVDWSRL--KELKPPFVPEVN-GDS 321
Query: 426 DTSQY 430
DTS +
Sbjct: 322 DTSHF 326
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 162 bits (411), Expect = 7e-40
Identities = 87/288 (30%), Positives = 155/288 (53%), Gaps = 18/288 (6%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
+G + +++ R LG G+F +V+ R+ G A+ + E ++
Sbjct: 4 NGIVLMRKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISV 63
Query: 197 LSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 256
+ +V HP ++ + +++ M+Y++GGELF + K + N +A+ Y ++ A+
Sbjct: 64 MRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLKEN-IARKYFQQLIGAI 122
Query: 257 EYLHSKGIIYRDLKPENILLDKNGHIKLTDFGF-----AKYVPDVTYTLCGTPDYIAPEV 311
+Y HS+G+ +RDLKPEN+LLD+NG +K++DFG +K + +T CGTP Y+APEV
Sbjct: 123 DYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEV 182
Query: 312 VSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDL 370
+ K Y+ D WS GV++Y +LAG+ PF++ N ++ Y I + P +F + + L
Sbjct: 183 IGKKGYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKL 242
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP 418
+S+++ + + R+ E + + WF + K IETP P
Sbjct: 243 LSRILDPNPNSRI-----KIEKIMENSWFQKGF------KKIETPKSP 279
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 162 bits (409), Expect = 1e-39
Identities = 87/296 (29%), Positives = 157/296 (52%), Gaps = 19/296 (6%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ + LG G+F +V+L ++ +G A+ H E ++L V HP+
Sbjct: 74 YELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPY 133
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+ ++ +++ +M+Y+ GGELF+ + K R P A+ Y ++ ++ + H +G+
Sbjct: 134 IVHLFEVMATKSKIYFVMEYVGGGELFNTVAKG-RLPEETARRYFQQLISSVSFCHGRGV 192
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPD-----VTYTLCGTPDYIAPEVVSTKPYNK 319
+RDLKPEN+LLD G++K++DFG + + +T CGTP YIAPEV++ K Y+
Sbjct: 193 YHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDA 252
Query: 320 S-VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+ D WS GV+++ ++AG+ PFYD N + Y+ I R P +F SD L+++L+ +
Sbjct: 253 AKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTN 312
Query: 379 LSQRLGNLQNGSEDVKNHPWFSE-------VVWEKLLCKNIETPYEPPIQAGQGDT 427
R+ ++ + WF + + + LC+ E E +G+ T
Sbjct: 313 PDTRI-----TIPEIMKNRWFKKGFKHVKFYIEDDKLCREDEDEEEEASSSGRSST 363
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 162 bits (409), Expect = 1e-39
Identities = 93/287 (32%), Positives = 152/287 (52%), Gaps = 13/287 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F++ R LG G FG V + G+ YA E+ +L ++ PF
Sbjct: 309 FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPF 368
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGEL-FSLLRKSQR--FPNPVAKFYAAEVCLALEYLHS 261
++ + ++ L +++ + GG+L F + F A+FYAAEV L++LH
Sbjct: 369 VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHK 428
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYNK 319
+GI+YRD KPENILLD +GH++++D G A +P ++ GT Y+APEV+ + Y
Sbjct: 429 QGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGEMVRGRVGTVGYMAPEVIDNEKYAF 488
Query: 320 SVDWWSFGVLIYEMLAGYTPF-YDSNTIKTYE---NILNAPVRFPPFFHSDAQDLISKLI 375
S DW+SFG L+YEM+ G PF +K E + P ++ F+ +A+ + +L+
Sbjct: 489 SPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLL 548
Query: 376 TRDLSQRLG--NLQNGSEDVKNHPWF--SEVVWEKLLCKNIETPYEP 418
+ + QRLG N + G +DV HP+F +++ W +L +E P+ P
Sbjct: 549 AKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEAGMLEPPFVP 595
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 161 bits (407), Expect = 2e-39
Identities = 95/273 (34%), Positives = 138/273 (49%), Gaps = 11/273 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ TLGTG+F V L G+ +A+ +E +L + H
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESS--IENEIAVLRKIKHEN 80
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+ + ++ L+++M + GGELF + + + A +V A+ YLH GI
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140
Query: 265 IYRDLKPENILL---DKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYNK 319
++RDLKPEN+L D+ I ++DFG +K DV T CGTP Y+APEV++ KPY+K
Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
+VD WS GV+ Y +L GY PFYD N K +E IL A F + D D I R+L
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI-RNL 259
Query: 380 SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNI 412
++ N + E HPW + + L KNI
Sbjct: 260 MEKDPNKRYTCEQAARHPW---IAGDTALNKNI 289
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 161 bits (407), Expect = 2e-39
Identities = 83/260 (31%), Positives = 146/260 (55%), Gaps = 11/260 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ RT+G G+F +V ++ G AM + E +++ +V HP
Sbjct: 9 YELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPC 68
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++R++ ++++I++YI GGELF + ++ R A+ Y ++ ++Y HSKG+
Sbjct: 69 VVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGV 128
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPD----VTYTLCGTPDYIAPEVVSTKPYNKS 320
+RDLKPEN+LLD G++K++DFG + +P+ + T CGTP+Y+APEV+S K YN +
Sbjct: 129 YHRDLKPENLLLDSQGNLKISDFGLSA-LPEQGVTILKTTCGTPNYVAPEVLSHKGYNGA 187
Query: 321 V-DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
V D WS GV++Y ++AGY PF + + Y I A P +F A+ LI++++ +
Sbjct: 188 VADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCPSYFALGAKSLINRILDPNP 247
Query: 380 SQRLGNLQNGSEDVKNHPWF 399
R+ +++ WF
Sbjct: 248 ETRI-----TIAEIRKDEWF 262
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 160 bits (405), Expect = 4e-39
Identities = 90/257 (35%), Positives = 142/257 (55%), Gaps = 13/257 (5%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXX-XXXEHTND 192
RV GKY ++ R LG G+F +V+ + G A+ E
Sbjct: 6 RVLFGKY-----EMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKR 60
Query: 193 ERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEV 252
E +++ +V HP I+ + ++F +M++++GGELF + K + A+ Y ++
Sbjct: 61 EISIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKG-KLHEDAARRYFQQL 119
Query: 253 CLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT-----YTLCGTPDYI 307
A++Y HS+G+ +RDLKPEN+LLD+NG +K++DFG + + +T CGTP Y+
Sbjct: 120 ISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAYV 179
Query: 308 APEVVSTKPYNKS-VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD 366
APEV+ K Y+ + D WS GV++Y +LAG PF D N + Y I A FPP+F +
Sbjct: 180 APEVLKKKGYDGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPWFSPE 239
Query: 367 AQDLISKLITRDLSQRL 383
A+ LISKL+ D +R+
Sbjct: 240 ARRLISKLLVVDPDRRI 256
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 159 bits (402), Expect = 8e-39
Identities = 85/261 (32%), Positives = 134/261 (50%), Gaps = 7/261 (2%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L +++I +TLG GSF +V L G A+ E +L +
Sbjct: 16 LPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLM 75
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HP IIR + + ++++M+Y++ GELF + + + A+ ++ +EY H
Sbjct: 76 HPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHR 135
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPYNK 319
I++RDLKPEN+LLD +IK+ DFG + + D + T CG+P+Y APEV+S KPY
Sbjct: 136 NMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGP 195
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDL 379
VD WS GV++Y +L G PF D N +E I P A+DLI +++ D
Sbjct: 196 DVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDP 255
Query: 380 SQRLGNLQNGSEDVKNHPWFS 400
+ R+ +++ HPWF+
Sbjct: 256 TMRI-----SITEIRQHPWFN 271
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 158 bits (399), Expect = 2e-38
Identities = 81/262 (30%), Positives = 146/262 (54%), Gaps = 12/262 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXX-XXXEHTNDERNMLSIVSHP 203
+++ + LG G+F +V R G+ A+ + E +++ +SHP
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I+++ ++F M++++GGELF+ + K R +++ Y ++ A+ Y H++G
Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYV----PD-VTYTLCGTPDYIAPEVVSTKPY- 317
+ +RDLKPEN+L+D+NG++K++DFG + PD + +TLCGTP Y+APE++S K Y
Sbjct: 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE 200
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
VD WS G++++ ++AGY PF D N + Y+ I RFP + D + +S+L+
Sbjct: 201 GAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDI 260
Query: 378 DLSQRLGNLQNGSEDVKNHPWF 399
+ R+ +++ PWF
Sbjct: 261 NPETRI-----TIDEILKDPWF 277
>Hs4885347 [T] KOG0986 G protein-coupled receptor kinase
Length = 500
Score = 157 bits (398), Expect = 2e-38
Identities = 95/282 (33%), Positives = 141/282 (49%), Gaps = 8/282 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ R LG G FG V + G+ YA +E+ +L V F
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRF 214
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGEL-FSLLRKSQR-FPNPVAKFYAAEVCLALEYLHSK 262
++ + ++ L +++ + GG+L F + F A FYAAE+C LE L +
Sbjct: 215 VVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRE 274
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYT--LCGTPDYIAPEVVSTKPYNKS 320
I+YRDLKPENILLD GHI+++D G A +P+ GT Y+APEVV+ + Y S
Sbjct: 275 RIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFS 334
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYE----NILNAPVRFPPFFHSDAQDLISKLIT 376
DWW G LIYEM+ G++PF +E I N + F DA+ + L+T
Sbjct: 335 PDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLT 394
Query: 377 RDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP 418
++ S+RLG G+ VK HP F ++ + +L +E P+ P
Sbjct: 395 KNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 157 bits (397), Expect = 3e-38
Identities = 81/263 (30%), Positives = 145/263 (54%), Gaps = 12/263 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ R LG G+F +V+L R+ +G A+ H E ++L V HP
Sbjct: 28 YEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHIKREISILRRVRHPN 87
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I++++ +++ +M+Y++GGELF+ + K R +A+ Y ++ A+ + H +G+
Sbjct: 88 IVQLFEVMATKSKIYFVMEYVKGGELFNKVAKG-RLKEEMARKYFQQLISAVSFCHFRGV 146
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPDVT-----YTLCGTPDYIAPEVVSTKPYN- 318
+RDLKPEN+LLD+NG++K++DFG + + +T CGTP Y+APEV++ K Y+
Sbjct: 147 YHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYDG 206
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
VD WS GV+++ ++AG+ PF+D N + Y+ I R P +F + L+ +++
Sbjct: 207 AKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGDFRCPRWFPVEINRLLIRMLETK 266
Query: 379 LSQRLGNLQNGSEDVKNHPWFSE 401
+R D+ WF +
Sbjct: 267 PERRF-----TMPDIMETSWFKK 284
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 157 bits (396), Expect = 4e-38
Identities = 98/280 (35%), Positives = 143/280 (51%), Gaps = 21/280 (7%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
+YDF+ + LGTG+F V L + A+ +E +L +
Sbjct: 19 IYDFRDV--LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS--MENEIAVLHKIK 74
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HP I+ + ++ L++IM + GGELF + + + A +V A++YLH
Sbjct: 75 HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHD 134
Query: 262 KGIIYRDLKPENIL---LDKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKP 316
GI++RDLKPEN+L LD++ I ++DFG +K V T CGTP Y+APEV++ KP
Sbjct: 135 LGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKP 194
Query: 317 YNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD----AQDLIS 372
Y+K+VD WS GV+ Y +L GY PFYD N K +E IL A F + D A+D I
Sbjct: 195 YSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIR 254
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNI 412
L+ +D +R E HPW + + L KNI
Sbjct: 255 HLMEKDPEKRF-----TCEQALQHPW---IAGDTALDKNI 286
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 157 bits (396), Expect = 4e-38
Identities = 91/268 (33%), Positives = 133/268 (48%), Gaps = 8/268 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF++ LG G FGRV+L R H+ AM E + S + HP
Sbjct: 52 DFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHP 111
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLR--KSQRFPNPVAKFYAAEVCLALEYLHS 261
I+R+ F D ++++ ++ GELF LR + RF P + Y +V AL Y H
Sbjct: 112 HILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHL 171
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD-VTYTLCGTPDYIAPEVVSTKPYNKS 320
+I+RDLKPENILL +KL DFG++ + P+ TLCGT DY+ PE+V Y+ S
Sbjct: 172 NNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLPPEMVDGNSYDDS 231
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VD W G+L YE + G PF ++T TY I + +P ++LI L+ ++
Sbjct: 232 VDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLRKESK 291
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLL 408
R+ + DV H W + E+ L
Sbjct: 292 GRITLV-----DVMTHYWVKAGMAEREL 314
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 156 bits (395), Expect = 5e-38
Identities = 80/261 (30%), Positives = 144/261 (54%), Gaps = 12/261 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ R LG G+F +V+ RSNH A+ + E +++ I HP
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKREISVMRIAKHPN 71
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++ ++ +++ +++Y +GGELF+ + K + VA Y ++ A+++ HS+G+
Sbjct: 72 VVELYEVMATKSRIYFVIEYCKGGELFNKVAKG-KLKEDVAWKYFYQLISAVDFCHSRGV 130
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFA-----KYVPDVTYTLCGTPDYIAPEVVSTKPY-N 318
+RD+KPEN+LLD N ++K++DFG + K + +T CGTP Y+APEV++ K Y
Sbjct: 131 YHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYEG 190
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
D WS GV+++ +LAGY PF+D+N ++ Y I A + P +F + + L+ K++ +
Sbjct: 191 TKADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKIGKADFKCPSWFAPEVKRLLCKMLDPN 250
Query: 379 LSQRLGNLQNGSEDVKNHPWF 399
R+ + +K WF
Sbjct: 251 HETRITIAK-----IKESSWF 266
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 156 bits (394), Expect = 7e-38
Identities = 93/286 (32%), Positives = 146/286 (50%), Gaps = 8/286 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F+ R LG G FG V + G+ YA +E+ +L V+ F
Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQF 245
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGEL-FSLLRKSQR-FPNPVAKFYAAEVCLALEYLHSK 262
++ + ++ L +++ + GG+L F + F A FYAAE+ LE LH +
Sbjct: 246 VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRE 305
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYNKS 320
+YRDLKPENILLD GHI+++D G A +P D+ GT Y+APEV++ + Y S
Sbjct: 306 NTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLS 365
Query: 321 VDWWSFGVLIYEMLAGYTPFYD-SNTIKTYE---NILNAPVRFPPFFHSDAQDLISKLIT 376
D+W G LIYEM+ G +PF +K E +L + F +A+ + L+T
Sbjct: 366 PDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLT 425
Query: 377 RDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
+D QRLG + G+ +VK HP+F + +++L ++ P+ P +A
Sbjct: 426 KDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRA 471
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 156 bits (394), Expect = 7e-38
Identities = 86/260 (33%), Positives = 145/260 (55%), Gaps = 17/260 (6%)
Query: 149 RTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPFIIRM 208
R +G G+F V R + YAM + + E ++ +SHP I+++
Sbjct: 288 RVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKE--DMVDSEILIIQSLSHPNIVKL 345
Query: 209 WGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIYRD 268
++ ++++I++Y++GG+LF + +S +FP P A ++C AL ++H K I++RD
Sbjct: 346 HEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRD 405
Query: 269 LKPENILL----DKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWW 324
LKPEN+L+ DK+ +KL DFG AK+V +T+CGTP Y+APE++S K Y VD W
Sbjct: 406 LKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMW 465
Query: 325 SFGVLIYEMLAGYTPFY--DSNTIKTYENILNAPVRF-PPFFHS---DAQDLISKLITRD 378
+ GV++Y +L G+ PF + + + + I F PP++ + A+DL+S+L+ D
Sbjct: 466 AAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVD 525
Query: 379 LSQRLGNLQNGSEDVKNHPW 398
+R + V HPW
Sbjct: 526 PKKRY-----TAHQVLQHPW 540
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 156 bits (394), Expect = 7e-38
Identities = 84/261 (32%), Positives = 135/261 (51%), Gaps = 8/261 (3%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L ++++ RTLG GSFGRV + G A+ E E +L +
Sbjct: 16 LPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 75
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HP IIR++ + ++++M+Y+ GELF + + R A+ + ++ +EY H
Sbjct: 76 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 135
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPY-N 318
+++RDLKPEN+LLD ++K+ DFG + + D + T CG+P+Y APEV+S K Y
Sbjct: 136 NMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAG 195
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
VD WS GV++Y +L G PF D N ++ I P A+DLI +++ D
Sbjct: 196 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVD 255
Query: 379 LSQRLGNLQNGSEDVKNHPWF 399
+R+ +++ HPWF
Sbjct: 256 PMKRV-----TIPEIRQHPWF 271
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 155 bits (393), Expect = 9e-38
Identities = 100/335 (29%), Positives = 158/335 (46%), Gaps = 33/335 (9%)
Query: 131 LKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHT 190
LKA++ G Y L + TLG G+FG+V + A+
Sbjct: 16 LKAQIKIGHYILKE-----TLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKI 70
Query: 191 NDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA 250
E LS+ HP IIR++ +FMIM+++ GGELF + K R A+ +
Sbjct: 71 RREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQ 130
Query: 251 EVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIA 308
++ ++Y H +++RDLKPEN+LLD+ ++K+ DFG + + D + T CG+P+Y A
Sbjct: 131 QIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAA 190
Query: 309 PEVVSTKPY-NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDA 367
PEV+S K Y VD WS GV++Y +L G PF D + + I + P F
Sbjct: 191 PEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPI 250
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG-- 425
+L+ ++ D +R +DV H WF K++ PPI +
Sbjct: 251 VNLLHHMLCVDPMKRA-----TIKDVIAHEWFQ---------KDLPNYLFPPINESEASI 296
Query: 426 -------DTSQYDRY--PEEEVNYGIQGEDPYHSI 451
+ +++ RY EEEV + G+DP+H +
Sbjct: 297 VDIEAVREVTEFQRYHVAEEEVTSALLGDDPHHHL 331
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 155 bits (393), Expect = 9e-38
Identities = 80/259 (30%), Positives = 144/259 (54%), Gaps = 9/259 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ RT+G G+F +V R+ G A+ + E +++ IV HP
Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+R++ +++++++++ GGELF + R ++ Y ++ A+ + H KG+
Sbjct: 71 IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGV 130
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYNKS- 320
+RDLKPEN+LLD NG++K++DFG + ++ T CGTP+Y+APEV+S + Y+ S
Sbjct: 131 YHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSA 190
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
D WS GV+++ +LAGY PF +++ Y I A PP+F ++ + LI +++ +
Sbjct: 191 ADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPK 250
Query: 381 QRLGNLQNGSEDVKNHPWF 399
R+ + +K PWF
Sbjct: 251 TRI-----QIQGIKKDPWF 264
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 155 bits (392), Expect = 1e-37
Identities = 89/296 (30%), Positives = 154/296 (51%), Gaps = 26/296 (8%)
Query: 132 KARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTN 191
KA+ K + DF+ +G G++ V L S + YA ++ +
Sbjct: 166 KAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVS 225
Query: 192 DERNMLSIVSH-PFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA 250
E+ L +++ P ++R++ TFQD L+ +++Y G+ SL++K A++YAA
Sbjct: 226 IEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAA 285
Query: 251 EVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-------------- 296
++ A++YLHS GII+RD+KPENILLD IKLTDFG AK +
Sbjct: 286 QIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTR 345
Query: 297 TYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAP 356
+ + GT +Y++PE+++ + D W+FG ++++M+AG PF +N T++ ++
Sbjct: 346 SKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQ 405
Query: 357 VRFPPFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEV------VWEK 406
F P F +DL+ K++ ++L +RL Q +K H +F ++ VW K
Sbjct: 406 YAFTPGFPLIIRDLVKKILVKNLDRRLTISQ-----IKEHHFFKDLNFKDGSVWSK 456
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 155 bits (392), Expect = 1e-37
Identities = 87/262 (33%), Positives = 136/262 (51%), Gaps = 16/262 (6%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F + LG+G+F V LV+ G+ +A+ E+ E +L + H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIAVLKKIKHEN 79
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+ + ++ + +++M + GGELF + + + A +V A++YLH GI
Sbjct: 80 IVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGI 139
Query: 265 IYRDLKPENILL---DKNGHIKLTDFGFAKYVPD-VTYTLCGTPDYIAPEVVSTKPYNKS 320
++RDLKPEN+L ++N I +TDFG +K + + T CGTP Y+APEV++ KPY+K+
Sbjct: 140 VHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKA 199
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD----AQDLISKLIT 376
VD WS GV+ Y +L GY PFY+ K +E I F F D A+D I L+
Sbjct: 200 VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLE 259
Query: 377 RDLSQRLGNLQNGSEDVKNHPW 398
+D ++R E +HPW
Sbjct: 260 KDPNERY-----TCEKALSHPW 276
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 154 bits (389), Expect = 3e-37
Identities = 87/287 (30%), Positives = 149/287 (51%), Gaps = 15/287 (5%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F R LG G FG V + G+ YA + E+ +L V F
Sbjct: 190 FLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKVHSRF 249
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGEL----FSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
I+ + F+ L ++M + GG++ +++ ++ FP P A FY A++ LE+LH
Sbjct: 250 IVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIICGLEHLH 309
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPY 317
+ I+YRDLKPEN+LLD +G+++++D G A + D T GTP ++APE++ + Y
Sbjct: 310 QRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMAPELLQGEEY 369
Query: 318 NKSVDWWSFGVLIYEMLAGYTPF------YDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
+ SVD+++ GV +YEM+A PF ++ +K I++ PV++P F ++D
Sbjct: 370 DFSVDYFALGVTLYEMIAARGPFRARGEKVENKELK--HRIISEPVKYPDKFSQASKDFC 427
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP 418
L+ +D +RLG + ++ HP F ++ W +L + P+ P
Sbjct: 428 EALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIP 474
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 154 bits (389), Expect = 3e-37
Identities = 81/276 (29%), Positives = 154/276 (55%), Gaps = 12/276 (4%)
Query: 138 GKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNML 197
G + +++ + LG G+F +V+ R G A+ E E + +
Sbjct: 5 GSVLMLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAM 64
Query: 198 SIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 257
++ HP I+ + +++ +M++++GGELF+ + + + VA+ Y ++ A++
Sbjct: 65 RLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVD 123
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGF-----AKYVPDVTYTLCGTPDYIAPEVV 312
+ HS+G+ +RDLKPEN+LLD++G++K++DFG ++ + +T CGTP Y+APEV+
Sbjct: 124 FCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVI 183
Query: 313 STKPYNK-SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
S Y+ D WS GV+++ +LAGY PF DSN ++ Y+ I A V+FP + A+ L+
Sbjct: 184 SRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRLL 243
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKL 407
+++ + + R+ +E + WF + + E++
Sbjct: 244 KRILDPNPNTRV-----STEKIMKSSWFRKGLQEEV 274
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 154 bits (389), Expect = 3e-37
Identities = 75/238 (31%), Positives = 135/238 (56%), Gaps = 6/238 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
++++ RTLG GSF +V ++ G A+ E E + + ++ HP
Sbjct: 18 NYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKLIKHP 77
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
++ + +++++++ + GGELF + + R A+ Y ++ A++Y HS+G
Sbjct: 78 NVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVDYCHSRG 137
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-----TYTLCGTPDYIAPEVVSTKPYN 318
+ +RDLKPEN++LD NG +K++DFG + + V +T CGTP+Y+APEV+S K Y+
Sbjct: 138 VYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEVLSDKGYD 197
Query: 319 -KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
+ D WS GV+++ ++AGY PF + N + Y+ I A PP+F A+ +I +++
Sbjct: 198 GAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCPPWFSQGAKRVIKRIL 255
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 153 bits (387), Expect = 4e-37
Identities = 83/261 (31%), Positives = 137/261 (51%), Gaps = 8/261 (3%)
Query: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
L ++++ +TLG GSFG+V + G A+ E E +L +
Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
HP IIR + + + ++++M+Y++ GELF + + R A+ + ++ +EY H
Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 136
Query: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPY-N 318
+++RDLKPEN+LLD +IK+ DFG + + D + T CG+P+Y APEV+S K Y
Sbjct: 137 NMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAG 196
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
VD WS GV++Y +L G PF D N ++ I P S+A+DLI +++ D
Sbjct: 197 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVD 256
Query: 379 LSQRLGNLQNGSEDVKNHPWF 399
+R+ +++ H WF
Sbjct: 257 PVKRI-----TIPEIRQHRWF 272
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 153 bits (386), Expect = 6e-37
Identities = 100/345 (28%), Positives = 162/345 (45%), Gaps = 59/345 (17%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DFQIL +G G +G+V+L + + A+ H ER++L+
Sbjct: 168 DFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSD 227
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
+++++ FQD + L++ M+++ GG+ +LL ++ + A+FY +E+ A+ LH G
Sbjct: 228 WLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELG 287
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFA--------------------------------- 290
+RDLKPEN L+D GHIKLTDFG A
Sbjct: 288 YTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIE 347
Query: 291 ----------KYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF 340
K + ++ G+PDY+A EV+ K Y+ +VD+WS G +++E L GYTPF
Sbjct: 348 DRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPF 407
Query: 341 YDSNTIKTYENI--LNAPVRFP------PFFHSDAQDLISKLITRDLSQRLGNLQNGSED 392
S+T +TYEN+ +R P F DLI++LI + N E
Sbjct: 408 SGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPI-----NRVRSFEQ 462
Query: 393 VKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEE 437
V+ +F+E+ +E L + P+ P + + D +D + EE
Sbjct: 463 VRKMSYFAEINFETL--RTSSPPFIPQLD-DETDAGYFDDFTNEE 504
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 153 bits (386), Expect = 6e-37
Identities = 80/274 (29%), Positives = 143/274 (51%), Gaps = 12/274 (4%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R G + ++I + LG GSF +V+L R+ H+G A+ H E
Sbjct: 46 RTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKRE 105
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
++L V HP+I+ + +++++M+Y+ GGEL++ + + R A+ Y ++
Sbjct: 106 ISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARG-RLREGTARRYFQQLI 164
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD-----VTYTLCGTPDYIA 308
++ + HS+G+ +RDLK EN+LLD G++K++DFG + + T CGTP Y+A
Sbjct: 165 SSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLA 224
Query: 309 PEVVSTKPY-NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDA 367
PEV++ K Y D WS GV+++ ++AGY PF D N + Y I + P +F +
Sbjct: 225 PEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPEL 284
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
L+++++ + R+ ++ H WF +
Sbjct: 285 ARLVTRMLDTNPDTRI-----TIPEIMKHRWFKK 313
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 152 bits (385), Expect = 8e-37
Identities = 85/242 (35%), Positives = 134/242 (55%), Gaps = 5/242 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+ +L +G GSFGRV+ R ++ + A+ + E ++ + HP
Sbjct: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKEL-RNLQREIEIMRGLRHPN 62
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+ M +F+ +++ ++ DY EG ELF +L + P + AA++ AL YLHS I
Sbjct: 63 IVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI 121
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLC---GTPDYIAPEVVSTKPYNKSV 321
++RD+KP+NILL K G IKL DFGFA+ + T L GTP Y++PE+V +PY+ +
Sbjct: 122 LHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTA 181
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
D WS G ++YE+ G PFY ++ + IL PVR+P ++ + L+T+D Q
Sbjct: 182 DLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQ 241
Query: 382 RL 383
RL
Sbjct: 242 RL 243
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 152 bits (385), Expect = 8e-37
Identities = 98/333 (29%), Positives = 155/333 (46%), Gaps = 31/333 (9%)
Query: 131 LKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHT 190
LKA++ G Y L + TLG G+FG+V + A+
Sbjct: 16 LKAQIKIGHYILKE-----TLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKI 70
Query: 191 NDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA 250
E LS+ HP IIR++ +FMIM+++ GGELF + K R A+ +
Sbjct: 71 RREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQ 130
Query: 251 EVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIA 308
++ ++Y H +++RDLKPEN+LLD+ ++K+ DFG + + D + T CG+P+Y A
Sbjct: 131 QIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAA 190
Query: 309 PEVVSTKPY-NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDA 367
PEV+S K Y VD WS GV++Y +L G PF D + + I + P F
Sbjct: 191 PEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPI 250
Query: 368 QDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQG-- 425
+L+ ++ D +R +DV H WF K++ PPI +
Sbjct: 251 VNLLHHMLCVDPMKRA-----TIKDVIAHEWFQ---------KDLPNYLFPPINESEASI 296
Query: 426 -------DTSQYDRYPEEEVNYGIQGEDPYHSI 451
+ ++ EEEV + G+DP+H +
Sbjct: 297 VDIEAVREVTERYHVAEEEVTSALLGDDPHHHL 329
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 152 bits (384), Expect = 1e-36
Identities = 89/284 (31%), Positives = 149/284 (52%), Gaps = 22/284 (7%)
Query: 139 KYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
K + DF+ LG GS+ V L + +G+ YA+ ++ E+ L
Sbjct: 119 KMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQ 178
Query: 199 IVSHPF-IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 257
++ I +++ TFQD L+ +++Y G+ L++K A++YA+++ A++
Sbjct: 179 KLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVD 238
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD----------------VTYTLC 301
LH+ GII+RD+KPENILLDKN +KLTDFG AK +P+ + +
Sbjct: 239 SLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFV 298
Query: 302 GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPP 361
GT +Y++PE+++ + D W+FG ++Y+MLAG PF +N T++ ++ F
Sbjct: 299 GTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTA 358
Query: 362 FFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWE 405
F +DL+ KL+ RD + RL Q +K H +F EV +E
Sbjct: 359 GFPQIVKDLVKKLLVRDPNDRLTIKQ-----IKAHLFFHEVNFE 397
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 152 bits (384), Expect = 1e-36
Identities = 90/269 (33%), Positives = 134/269 (49%), Gaps = 14/269 (5%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
+G + +F I T+G G+FG V G A+ T +E +
Sbjct: 16 TGHLKIGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDN 75
Query: 197 LSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLAL 256
L ++HP I R++ +F++M+ + GGELFS + + P ++ Y ++ +
Sbjct: 76 LQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGV 135
Query: 257 EYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVST 314
Y H+ I++RDLKPEN+LLD N +IK+ DFG + Y+ D+ T CG+P+Y APE++S
Sbjct: 136 SYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTACGSPNYAAPELISN 195
Query: 315 KPY-NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISK 373
K Y VD WS GV++Y ML G PF D N + I + P A DLIS
Sbjct: 196 KLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLIST 255
Query: 374 LITRDLSQRLGNLQNGSEDVK---NHPWF 399
++ D +R DVK NH WF
Sbjct: 256 MLQVDPVKR--------ADVKRIVNHSWF 276
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 151 bits (381), Expect = 2e-36
Identities = 82/263 (31%), Positives = 146/263 (55%), Gaps = 12/263 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ + +G G+F +V+ RS G+ A+ + E ++ + HP
Sbjct: 22 YEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQREIAIMHRLRHPS 81
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+R++ ++F +M++ +GGELF+ + K RF +++ Y ++ A+ Y HS+GI
Sbjct: 82 IVRLFEVLATKSKIFFVMEFAKGGELFAKVSKG-RFCEDLSRRYFQQLISAVGYCHSRGI 140
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYV----PD-VTYTLCGTPDYIAPEVVSTKPYN- 318
+RDLKPEN+LLD+ +K++DFG + PD + +TLCGTP Y+APEV++ K Y+
Sbjct: 141 FHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDG 200
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+D WS G++++ + AGY PF D N + Y I R P + D + L+++L+ +
Sbjct: 201 AKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPKWTSPDLRRLLTRLLDTN 260
Query: 379 LSQRLGNLQNGSEDVKNHPWFSE 401
R+ E++ + PWF +
Sbjct: 261 PQTRI-----TIEEIIHDPWFKQ 278
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 150 bits (380), Expect = 3e-36
Identities = 94/309 (30%), Positives = 154/309 (49%), Gaps = 29/309 (9%)
Query: 137 SGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE-RN 195
+G L +++ R LG+GSF +VH+ RS G A+ E
Sbjct: 13 TGTVLLGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEA 72
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
M + +HP ++++ +++++++Y GGELF+ L + R A+ Y ++ A
Sbjct: 73 MRRLHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASA 132
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD------VTYTLCGTPDYIAP 309
L + H GI +RD+KP+N+LLDK G++K++DFG + +P+ + +T CGTP Y AP
Sbjct: 133 LSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSA-LPEHRSNNGLLHTACGTPAYTAP 191
Query: 310 EVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQ 368
EV++ + Y+ D WS GV ++ +LAGY PF D+N + Y I RFP + A+
Sbjct: 192 EVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYRFPSWISKPAR 251
Query: 369 DLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTS 428
+I KL+ + R+ E V WF K++E I Q
Sbjct: 252 SIIYKLLDPNPETRM-----SIEAVMGTVWFQ---------KSLE------ISEFQSSVF 291
Query: 429 QYDRYPEEE 437
+ DR+ E+E
Sbjct: 292 ELDRFLEKE 300
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 150 bits (378), Expect = 5e-36
Identities = 95/340 (27%), Positives = 167/340 (48%), Gaps = 51/340 (15%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF+++ +G G +G+V+L R A+ +H ER++L+
Sbjct: 176 DFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSE 235
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
+++++ FQD Q L++ M+++ GG+ +LL ++ + A+FY +E+ A+ LH G
Sbjct: 236 WLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLG 295
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFA----------------KYVPDVTY--------- 298
+RDLKPEN L+D GHIKLTDFG A + + D+ +
Sbjct: 296 YTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIE 355
Query: 299 ------------------TLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF 340
++ G+PDY+A EV+ K Y+ +VD+WS G +++E L GYTPF
Sbjct: 356 DRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPF 415
Query: 341 YDSNTIKTYENILNAPVRFPPFFHSDAQDLIS----KLITRDLSQRLGNLQNGSEDVKNH 396
S+T +TY+N+ SD + S LITR ++ + L++ E VK
Sbjct: 416 SGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRLRS-FEHVKRM 474
Query: 397 PWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
+F+++ + L +++ P+ P + + + D +D + E
Sbjct: 475 SYFADINFSTL--RSMIPPFTPQLDS-ETDAGYFDDFTSE 511
>At3g27580 [R] KOG0610 Putative serine/threonine protein kinase
Length = 578
Score = 150 bits (378), Expect = 5e-36
Identities = 112/401 (27%), Positives = 175/401 (42%), Gaps = 96/401 (23%)
Query: 131 LKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHT 190
+++RV S A DF++++ LG G G V+L G +A+
Sbjct: 169 VRSRVGSSLEAK-DFKLIKKLGGGDIGNVYLAELIGTGVSFAVKVMEKAAIAARKKLVRA 227
Query: 191 NDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQR--FPNPVAKFY 248
E+ +L + HPF+ ++ F+ ++M++ GG+L SL +K + FP A+FY
Sbjct: 228 QTEKEILQSLDHPFLPTLYSHFETEMNSCLVMEFCPGGDLHSLRQKQRGKYFPEQAARFY 287
Query: 249 AAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFG-------------FAKYV-- 293
AEV LA+EYLH GIIYRDLKPEN+L+ ++GHI L+DF FA
Sbjct: 288 VAEVLLAMEYLHMLGIIYRDLKPENVLVREDGHIMLSDFDLSLRCAVSPTLVRFAAITLE 347
Query: 294 ---------------------PDVTYTLCGTPDYIA------------------PEVVST 314
PD +C TP +++ PE+++
Sbjct: 348 SKSSSYCIQPTCVDQSSCIVQPDCIQPVCFTPRFLSKGKHRKKSNDMSRQIRPLPELIAE 407
Query: 315 KPYNKSVDW-----------------------WSFGVLIYEMLAGYTPFYDSNTIKTYEN 351
+S+ + W+FG+ +YE+L G TPF + T N
Sbjct: 408 PTSARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGITPFRGGDNRATLFN 467
Query: 352 ILNAPVRFP--PFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLC 409
++ P+RFP P A+DLI L+ ++ RL + G+ ++K HP+F V W + C
Sbjct: 468 VVGQPLRFPEHPNVSFAARDLIRGLLVKEPQHRLA-YRRGATEIKQHPFFQSVNWALIRC 526
Query: 410 KN---IETPYEPPIQA---------GQGDTSQYDRYPEEEV 438
+ I P +P QA G G YD+ P +V
Sbjct: 527 TSPPQIPQPVKPMDQAHSVRHGFSQGHGHVG-YDKPPTVDV 566
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 149 bits (377), Expect = 6e-36
Identities = 87/263 (33%), Positives = 130/263 (49%), Gaps = 9/263 (3%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
+ L F+I R LG G FG+V L R G A+ E + S
Sbjct: 5 WTLDRFEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQIRREIEIHSN 64
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLR-KSQRFPNPVAKFYAAEVCLALEY 258
+ HP I+RM+G F D +++I++Y GE F L + +F Y +V LAL Y
Sbjct: 65 LKHPNILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSLYIRQVMLALTY 124
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-TYTLCGTPDYIAPEVVSTKPY 317
+ +I+RD+KPEN+LL + +K+ DFG+A Y D T CGT +Y+APE+V+ +
Sbjct: 125 MKECNVIHRDIKPENLLLGSDNQLKIADFGWAVYNADKRRMTFCGTMEYLAPEMVNNDIH 184
Query: 318 NKSVDWWSFGVLIYEMLAGYTPF--YDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
+ +D W G+L YE L G TPF + N + Y+ I + P S+A D IS+L+
Sbjct: 185 DSGIDLWCLGILTYEFLMGKTPFESKNRNMREAYKKINSLKYTIPETISSNASDFISRLL 244
Query: 376 TRDLSQRLGNLQNGSEDVKNHPW 398
R+ + NHP+
Sbjct: 245 VLSPGDRM-----ELTEALNHPF 262
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 149 bits (377), Expect = 6e-36
Identities = 91/309 (29%), Positives = 150/309 (48%), Gaps = 21/309 (6%)
Query: 150 TLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPFIIRMW 209
TLGTG+FG+V + A+ E L + HP II+++
Sbjct: 33 TLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLY 92
Query: 210 GTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIYRDL 269
+FMIM+Y+ GGELF + K + A+ + ++ ++Y H I++RDL
Sbjct: 93 QVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDL 152
Query: 270 KPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPY-NKSVDWWSF 326
KPEN+LLD N H+K+ DFG + + D + T CG+P+Y APEV+S K Y VD WS
Sbjct: 153 KPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSC 212
Query: 327 GVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQRLGNL 386
GV++Y +L G PF D + + I + P + + +L+ +++ D +R
Sbjct: 213 GVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRA--- 269
Query: 387 QNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEV--NYGIQG 444
E++K H WF + + L +IE D++ D Y EV +G++
Sbjct: 270 --NIEEIKKHEWFQKDLPAYLFPSSIEQ-----------DSNVIDTYAVAEVCTKFGVKE 316
Query: 445 EDPYHSIFT 453
+ ++S+ +
Sbjct: 317 TEVHNSLLS 325
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 149 bits (375), Expect = 1e-35
Identities = 89/267 (33%), Positives = 141/267 (52%), Gaps = 18/267 (6%)
Query: 143 YDFQILRTLGTGSFGRVHLVRSNHN-GRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVS 201
YDF+ + LGTG+F +V L S + G+ YA+ E +E +L +
Sbjct: 22 YDFRDV--LGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKE--ESLENEIKVLRKLR 77
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
H I++++ T+ + Q ++++M+ + GGELF + + A +V A+ ++H
Sbjct: 78 HNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHD 137
Query: 262 KGIIYRDLKPENILL---DKNGHIKLTDFGFAKYVPD-VTYTLCGTPDYIAPEVVSTKPY 317
G+++RDLKPEN+L D++ I ++DFG +K V T CGTP Y+APEV+ KPY
Sbjct: 138 NGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSGVMATACGTPGYVAPEVLQQKPY 197
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRF-PPFF---HSDAQDLISK 373
K+VD WS GV+ Y +L GY PFYD + + I+ F P++ A+D I+
Sbjct: 198 GKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFITH 257
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFS 400
L+ D R +D +HPW S
Sbjct: 258 LMCCDPEARF-----TCQDALSHPWIS 279
>CE01554 [T] KOG0986 G protein-coupled receptor kinase
Length = 642
Score = 148 bits (374), Expect = 1e-35
Identities = 90/304 (29%), Positives = 155/304 (50%), Gaps = 26/304 (8%)
Query: 143 YDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSH 202
+ F++ R LG G FG V + +G+ YA+ + +E+ +L ++
Sbjct: 201 HTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQRINS 260
Query: 203 PFIIRMWGTFQDSQQLFMIMDYIEGGEL----FSLLRKSQRFPNPVAKFYAAEVCLALEY 258
PF++ + ++ L +++ + GG+L ++L+ F +FYAAE+ L L++
Sbjct: 261 PFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGG--FDEKRVQFYAAEITLGLQH 318
Query: 259 LHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKP 316
LHS+ I+YRDLKPENILLD GH++++D G A + D GT Y+APE+V +
Sbjct: 319 LHSERILYRDLKPENILLDDFGHVRISDLGLAVEIKDNEPIKGRVGTVGYMAPEIVKNER 378
Query: 317 YNKSVDWWSFGVLIYEMLAGYTPFYD-SNTIKTYE---NILNAPVRFPPFFHSDAQDLIS 372
Y+ VDWW G LIYEM+ G PF +K E + ++ F A+ L
Sbjct: 379 YSYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQEKYSEKFSEAARTLCR 438
Query: 373 KLITRDLS-----QRLGNLQNGSEDVKNHPWFS---------EVVWEKLLCKNIETPYEP 418
L+ ++ +R+G ++G+E+++ HP+F+ V W+K+ + P+ P
Sbjct: 439 GLLHKEPGFRLGCRRVGRPEDGAEEIRAHPFFNTADTVTGREPVPWKKMEAGKVTPPFCP 498
Query: 419 PIQA 422
+A
Sbjct: 499 DPRA 502
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 148 bits (373), Expect = 2e-35
Identities = 85/298 (28%), Positives = 156/298 (51%), Gaps = 12/298 (4%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+ + R LG G+F +V+ RS + A+ E E +++ I HP
Sbjct: 12 YDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQIKREISVMRIARHPN 71
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++ ++ +++ +M+Y +GGELF+ + K + + VA Y ++ A+++ HS+ +
Sbjct: 72 VVELYEVMATKTRIYFVMEYCKGGELFNKVAKG-KLRDDVAWKYFYQLINAVDFCHSREV 130
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFA-----KYVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
+RD+KPEN+LLD N ++K++DFG + K + +T CGTP Y+APEV++ K Y+
Sbjct: 131 YHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYDG 190
Query: 320 S-VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRD 378
+ D WS GV+++ +LAGY PF+DSN ++ Y I A + P +F + + L+ K++ +
Sbjct: 191 TKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAPSWFAPEVRRLLCKMLDPN 250
Query: 379 LSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEE 436
R+ + ++ WF + + K ++AG T++ P E
Sbjct: 251 PETRITIAR-----IRESSWFRKGLHMKQKKMEKRVKEINSVEAGTAGTNENGAGPSE 303
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 147 bits (372), Expect = 2e-35
Identities = 103/320 (32%), Positives = 165/320 (51%), Gaps = 29/320 (9%)
Query: 141 ALYDFQIL-RTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXE-----HTNDER 194
AL D I+ +TLG+G+ G V L + A+ E + E
Sbjct: 215 ALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEI 274
Query: 195 NMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCL 254
+L ++HP II++ F D++ +++++ +EGGELF + ++R K Y ++ L
Sbjct: 275 EILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333
Query: 255 ALEYLHSKGIIYRDLKPENILL---DKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAP 309
A++YLH GII+RDLKPEN+LL +++ IK+TDFG +K + + + TLCGTP Y+AP
Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAP 393
Query: 310 EV---VSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNT-IKTYENILNAPVRFPPFFHS 365
EV V T YN++VD WS GV+++ L+GY PF + T + + I + F P +
Sbjct: 394 EVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWA 453
Query: 366 D----AQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEV----VWEKLLCKNIETPYE 417
+ A DL+ KL+ D R +E+ HPW + ++ LL + E+
Sbjct: 454 EVSEKALDLVKKLLVVDPKARF-----TTEEALRHPWLQDEDMKRKFQDLLSEENESTAL 508
Query: 418 PPIQAGQGDTSQYDRYPEEE 437
P + A + + R E E
Sbjct: 509 PQVLAQPSTSRKRPREGEAE 528
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 146 bits (369), Expect = 5e-35
Identities = 78/235 (33%), Positives = 133/235 (56%), Gaps = 6/235 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
++I RT+G G+F +V L NG + A+ E + +++HP
Sbjct: 12 YEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPN 71
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+++ ++ ++M+Y+ GG+L L + + + K + ++ A++Y H++G+
Sbjct: 72 IVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLFQ-QLIDAVDYCHNRGV 130
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVP---DVTYTLCGTPDYIAPEVVSTKPYN-KS 320
+RDLKP+N+LLD G++K++DFG + VP D+ T CG+P YIAPE++ K Y+ +
Sbjct: 131 YHRDLKPQNLLLDSKGNLKVSDFGLSA-VPKSGDMLSTACGSPCYIAPELIMNKGYSGAA 189
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
VD WS GV+++E+LAGY PF D Y+ IL A FPP F + + LI ++
Sbjct: 190 VDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNIL 244
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 146 bits (369), Expect = 5e-35
Identities = 88/280 (31%), Positives = 143/280 (50%), Gaps = 18/280 (6%)
Query: 129 STLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXE 188
+T A++ GKY L R LG+GSF +VHL RS + A+
Sbjct: 14 ATTPAKILLGKYELG-----RRLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEP 68
Query: 189 HTNDERN-MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKF 247
E + M + HP I+++ +++++M+ GGELFS + + R P A+
Sbjct: 69 RIIREIDAMRRLRHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARR 128
Query: 248 YAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD-----VTYTLCG 302
Y ++ AL + H G+ +RD+KP+N+LLD+ G++K++DFG + +P+ + +T CG
Sbjct: 129 YFQQLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSA-LPEHLQNGLLHTACG 187
Query: 303 TPDYIAPEVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPP 361
TP Y APEV+S + Y+ D WS GV+++ +L G PF DSN Y I RFP
Sbjct: 188 TPAYTAPEVISRRGYDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHRRDYRFPS 247
Query: 362 FFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
+ A+ +I +++ + R+ E V WF +
Sbjct: 248 WISKQAKSIIYQMLDPNPVTRM-----SIETVMKTNWFKK 282
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 146 bits (369), Expect = 5e-35
Identities = 86/272 (31%), Positives = 146/272 (53%), Gaps = 13/272 (4%)
Query: 139 KYALYD-FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNML 197
K AL+ + + + LG+G+F +V+ NG H E +++
Sbjct: 21 KSALFGKYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKREISVM 80
Query: 198 SIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 257
+ HP I+ + +++ +M+ +GGELFS + S RF +++ Y ++ A+
Sbjct: 81 RRLRHPHIVLLSEVLATKTKIYFVMELAKGGELFSRVT-SNRFTESLSRKYFRQLISAVR 139
Query: 258 YLHSKGIIYRDLKPENILLDKNGHIKLTDFGFA----KYVPD-VTYTLCGTPDYIAPEVV 312
Y H++G+ +RDLKPEN+LLD+N +K++DFG + + PD + +TLCGTP Y+APE++
Sbjct: 140 YCHARGVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELL 199
Query: 313 STKPYNKS-VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
K Y+ S D WS GV+++ + AGY PF D N + Y I A + P + SD + L+
Sbjct: 200 LKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYKLPDWTSSDLRKLL 259
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEVV 403
+L+ + R+ E++ PWF+ V
Sbjct: 260 RRLLEPNPELRI-----TVEEILKDPWFNHGV 286
>At2g34650 [R] KOG0610 Putative serine/threonine protein kinase
Length = 438
Score = 146 bits (369), Expect = 5e-35
Identities = 101/322 (31%), Positives = 148/322 (45%), Gaps = 67/322 (20%)
Query: 144 DFQILRTLGTGSFGRVHLVR-----SNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLS 198
DF+++R +G G G V+L R ++AM E+ +L
Sbjct: 74 DFRLMRRIGAGDIGTVYLCRLAGDEEESRSSYFAMKVVDKEALALKKKMHRAEMEKTILK 133
Query: 199 IVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLAL 256
++ HPF+ ++ F+ S ++M+Y GG+L SL + +RF A+FYAAEV +AL
Sbjct: 134 MLDHPFLPTLYAEFEASHFSCIVMEYCSGGDLHSLRHRQPHRRFSLSSARFYAAEVLVAL 193
Query: 257 EYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV-------------------- 296
EYLH GIIYRDLKPENIL+ +GHI L+DF + +
Sbjct: 194 EYLHMLGIIYRDLKPENILVRSDGHIMLSDFDLSLCSDSIAAVESSSSSPENQQLRSPRR 253
Query: 297 ----------------TYTLCGTPDYIAPEV-------VSTKPY-----------NKSVD 322
TL T ++A V V T Y +VD
Sbjct: 254 FTRLARLFQRVLRSKKVQTLEPTRLFVAEPVTARSGSFVGTHEYVAPEVASGGSHGNAVD 313
Query: 323 WWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP-----PFFHSDAQDLISKLITR 377
WW+FGV +YEM+ G TPF NI+ + FP F A++LIS L+ +
Sbjct: 314 WWAFGVFLYEMIYGKTPFVAPTNDVILRNIVKRQLSFPTDSPATMFELHARNLISGLLNK 373
Query: 378 DLSQRLGNLQNGSEDVKNHPWF 399
D ++RLG+ + G+ +VK HP+F
Sbjct: 374 DPTKRLGS-RRGAAEVKVHPFF 394
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 146 bits (368), Expect = 7e-35
Identities = 79/243 (32%), Positives = 133/243 (54%), Gaps = 5/243 (2%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
D+ ++ +G GSFGRV+ R + G+ AM E +L + H
Sbjct: 5 DYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKDIHS-LRQEIEILRKLKHE 63
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
II M +F+++++ ++ ++ +G ELF +L + P + A ++ AL+YLHS
Sbjct: 64 NIIEMLDSFENAREFCVVTEFAQG-ELFEILEDDKCLPEEQVQAIAKQLVKALDYLHSNR 122
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLC---GTPDYIAPEVVSTKPYNKS 320
II+RD+KP+NIL+ +KL DFGFA+ + T L GTP Y+APE+V +PY+++
Sbjct: 123 IIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVKEQPYDRT 182
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VD WS GV++YE+ G PFY ++ +I+ PV++P + + + L+ ++
Sbjct: 183 VDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKDPVKYPDEMSTYFESFLKGLLNKEPH 242
Query: 381 QRL 383
RL
Sbjct: 243 SRL 245
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 145 bits (367), Expect = 9e-35
Identities = 82/257 (31%), Positives = 131/257 (50%), Gaps = 9/257 (3%)
Query: 147 ILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPFII 206
I TLG GSFG+V L + A+ E + L ++ HP II
Sbjct: 36 IRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHII 95
Query: 207 RMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIY 266
+++ + M+++Y GGELF + + +R + + ++ A+EY H I++
Sbjct: 96 KLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVH 154
Query: 267 RDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPY-NKSVDW 323
RDLKPEN+LLD N ++K+ DFG + + D + T CG+P+Y APEV++ K Y VD
Sbjct: 155 RDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDV 214
Query: 324 WSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQRL 383
WS G+++Y ML G PF D ++ + + P F AQ LI ++I D QR+
Sbjct: 215 WSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQRI 274
Query: 384 GNLQNGSEDVKNHPWFS 400
++++ PWF+
Sbjct: 275 -----TIQEIRRDPWFN 286
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 145 bits (366), Expect = 1e-34
Identities = 84/268 (31%), Positives = 138/268 (51%), Gaps = 9/268 (3%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
++QI++TLG GSFG+V L G+ A+ E + L ++ HP
Sbjct: 54 NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHP 113
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
II+++ + ++ M+++Y G ELF + + + A+ + ++ A+EY H
Sbjct: 114 HIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHK 172
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPY-NKS 320
I++RDLKPEN+LLD++ ++K+ DFG + + D + T CG+P+Y APEV+S K Y
Sbjct: 173 IVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPE 232
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VD WS GV++Y ML PF D + ++NI N P F A LI +++ +
Sbjct: 233 VDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPL 292
Query: 381 QRLGNLQNGSEDVKNHPWFSEVVWEKLL 408
R+ ++ WF + E LL
Sbjct: 293 NRI-----SIHEIMQDDWFKVDLPEYLL 315
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 145 bits (366), Expect = 1e-34
Identities = 100/366 (27%), Positives = 165/366 (44%), Gaps = 72/366 (19%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ + + DF +L +G G+FG V L R G YAM EH E
Sbjct: 94 RLMRNRLCVDDFDLLSIIGRGAFGEVRLCREKKTGNIYAMKKLKKSEMLSRGQVEHVRAE 153
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
RN+L+ V+ I++++ +FQD + L++IM+Y+ GG++ +LL + + VA+FY A+
Sbjct: 154 RNLLAEVASDCIVKLYYSFQDPEYLYLIMEYLSGGDVMTLLMREETLTETVARFYIAQSV 213
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVS 313
LA+E +H ++RD+KP+N+LLDK GH+KL+DFG K + + + + E +
Sbjct: 214 LAIESIHKHNYVHRDIKPDNLLLDKYGHMKLSDFGLCKPLDCRNISAMNVNEPLNDENI- 272
Query: 314 TKPYNKSVD-------------W---------WSFG--VLIYEMLAGYTPFYDSNTIKTY 349
N+S+D W W L Y + TP Y + +
Sbjct: 273 ----NESIDGDENCSIGRRGRRWKSPLEQLQHWQINRRKLAYSTVG--TPDYIAPEVLLK 326
Query: 350 EN-------------ILNAPVRFPPFFHSDAQDLISKLIT-----------------RDL 379
+ + V +PPF+ D K+++ RDL
Sbjct: 327 KGYGVECDWWSLGAIMYEMLVGYPPFYSDDPVTTCRKIVSWRTHLVFPEGARLTPEARDL 386
Query: 380 --------SQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYD 431
RLG+ G+E +K H WF +V WEKL ++ ++P + G+ DT +
Sbjct: 387 ICRLLCDSEHRLGSHGAGAEQIKAHTWFKDVEWEKLY--EMDAAFKPVVN-GELDTQNFM 443
Query: 432 RYPEEE 437
++ E E
Sbjct: 444 KFDEVE 449
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 144 bits (363), Expect = 3e-34
Identities = 83/251 (33%), Positives = 136/251 (54%), Gaps = 6/251 (2%)
Query: 135 VTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDER 194
V Y +Y +I++TLG G+F +V L GR A+ + E
Sbjct: 55 VNGNGYGVY--KIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIAR-QKLYREV 111
Query: 195 NMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCL 254
N++ ++HP I+R+ + + L+++M+Y+ GGELF+ L K+ R A+ ++
Sbjct: 112 NIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVS 171
Query: 255 ALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFA-KYVPDVTY-TLCGTPDYIAPEVV 312
A+EY HSK I++RDLK EN+LLD+ +K+ DFGF+ + P T CG+P Y APE+
Sbjct: 172 AIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELF 231
Query: 313 STKPYN-KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
K Y+ VD WS GV++Y +++G PF +N + + +L R P + + + LI
Sbjct: 232 RGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLI 291
Query: 372 SKLITRDLSQR 382
K + + +QR
Sbjct: 292 RKFLVLNPTQR 302
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 144 bits (362), Expect = 4e-34
Identities = 93/266 (34%), Positives = 133/266 (49%), Gaps = 20/266 (7%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+ ILR LG+G+FG LVR NG FYA+ EH E + HP
Sbjct: 4 YDILRDLGSGNFGVAKLVREKANGEFYAVKYIERGLKID----EHVQREIINHRDLKHPN 59
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
IIR F L ++M+Y GGELF + + RF ++Y ++ + Y H+ I
Sbjct: 60 IIRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVSYCHAMQI 119
Query: 265 IYRDLKPENILLD--KNGHIKLTDFGFAK--YVPDVTYTLCGTPDYIAPEVVSTKPYN-K 319
+RDLK EN LLD + H+K+ DFG++K + + GTP Y+APEV+S K YN K
Sbjct: 120 CHRDLKLENTLLDGSPSSHLKICDFGYSKSSVLHSQPKSTVGTPAYVAPEVLSRKEYNGK 179
Query: 320 SVDWWSFGVLIYEMLAGYTPFYD----SNTIKTYENILNAPVRFPPF--FHSDAQDLISK 373
D WS GV +Y ML G PF D N T + IL+ P + S+ + L+S+
Sbjct: 180 IADVWSCGVTLYVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTIPDYVRISSECKHLLSR 239
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWF 399
+ D +R+ +++ HPWF
Sbjct: 240 IFVADPDKRI-----TVPEIEKHPWF 260
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 143 bits (361), Expect = 5e-34
Identities = 87/303 (28%), Positives = 153/303 (49%), Gaps = 38/303 (12%)
Query: 135 VTSGKYALYDFQILRTLGTGSFGRVHLVRSNHN-GRFYAMXXXXXXXXXXXXXXEHTNDE 193
+TS K + +DF LG GS+ V + + YA+ ++ E
Sbjct: 1 MTSRKRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIE 60
Query: 194 RNMLSIVS---HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA 250
+N +++++ H II+++ TF D + L+ ++D+ GGEL SLL K F + + + A
Sbjct: 61 KNTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTA 120
Query: 251 EVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV-PDVT------------ 297
++ ALE++HS GII+RDLKPEN+LLD++G + +TDFG A + P ++
Sbjct: 121 QLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNG 180
Query: 298 -------YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYE 350
+ GT +Y++PE++ D W+ G +IY+ + G PF N +KT+E
Sbjct: 181 SKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFE 240
Query: 351 NILNAPVRFPPFFHSDAQ---------DLISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
I+ + P + +L+ K++ ++++R+ E +K HP+FS+
Sbjct: 241 KIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERI-----SLEQIKRHPYFSK 295
Query: 402 VVW 404
V W
Sbjct: 296 VDW 298
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 143 bits (361), Expect = 5e-34
Identities = 83/262 (31%), Positives = 137/262 (51%), Gaps = 11/262 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF++ LG GSF V+ S H+G A+ + +E + + HP
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHP 70
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQR-FPNPVAKFYAAEVCLALEYLHSK 262
I+ ++ F+DS ++++++ GE+ L+ + F A+ + ++ + YLHS
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA---KYVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
GI++RDL N+LL +N +IK+ DFG A K + YTLCGTP+YI+PE+ + +
Sbjct: 131 GILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGL 190
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIK-TYENILNAPVRFPPFFHSDAQDLISKLITRD 378
D WS G + Y +L G PF D++T+K T ++ A P F +A+DLI +L+ R+
Sbjct: 191 ESDVWSLGCMFYTLLIGRPPF-DTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRRN 249
Query: 379 LSQRLGNLQNGSEDVKNHPWFS 400
+ RL V +HP+ S
Sbjct: 250 PADRL-----SLSSVLDHPFMS 266
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 143 bits (361), Expect = 5e-34
Identities = 83/282 (29%), Positives = 136/282 (47%), Gaps = 24/282 (8%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEH--------------- 189
++I +G G+F VHL R +G A+ +
Sbjct: 57 YEIGAIIGKGNFSSVHLTRRKEDGTKCALKVRYQSTLQFSFPSKFFQQVEKRAMRGKCFF 116
Query: 190 TNDERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYA 249
++E MLS++ H II + F Q F++ ++ + G+L+ +RK+ R P A
Sbjct: 117 VDNEVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAIIT 176
Query: 250 AEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAP 309
+V AL YLH + +++RD+KPEN+LL +KL DFG A ++ Y +CGTP Y AP
Sbjct: 177 LQVASALNYLHERNVVHRDVKPENLLLVDKFSVKLCDFGLACHILGPLYRICGTPTYCAP 236
Query: 310 EVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAP--VRFPPF--FHS 365
EV+ Y+ D WS GV++Y ML GY PF + + ++ I+ A + P +
Sbjct: 237 EVLRETGYSTRCDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNLDMPEWKGISL 296
Query: 366 DAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKL 407
A+DL+S+L+ + +R + + HPW + E +
Sbjct: 297 KAKDLVSRLMNKTEERR-----PLASQIMAHPWIAPYTMENI 333
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 143 bits (360), Expect = 6e-34
Identities = 83/262 (31%), Positives = 136/262 (51%), Gaps = 11/262 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
DF++ LG GSF V+ S H G A+ + +E + + HP
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHP 70
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQR-FPNPVAKFYAAEVCLALEYLHSK 262
I+ ++ F+DS ++++++ GE+ L+ + F A+ + ++ + YLHS
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA---KYVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
GI++RDL N+LL +N +IK+ DFG A K + YTLCGTP+YI+PE+ + +
Sbjct: 131 GILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGL 190
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIK-TYENILNAPVRFPPFFHSDAQDLISKLITRD 378
D WS G + Y +L G PF D++T+K T ++ A P F +A+DLI +L+ R+
Sbjct: 191 ESDVWSLGCMFYTLLIGRPPF-DTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRRN 249
Query: 379 LSQRLGNLQNGSEDVKNHPWFS 400
+ RL V +HP+ S
Sbjct: 250 PADRL-----SLSSVLDHPFMS 266
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 143 bits (360), Expect = 6e-34
Identities = 80/251 (31%), Positives = 137/251 (53%), Gaps = 5/251 (1%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++L+T+G G+F +V L + G A+ + + + M + HP
Sbjct: 122 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQL-DHPN 180
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I++++ + Q L+++++Y GGE+F L R A+ ++ A++YLHSK I
Sbjct: 181 IVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNI 240
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAK--YVPDVTYTLCGTPDYIAPEVVSTKPYN-KSV 321
I+RDLK EN+LLD++ +IK+ DFGF+ + + T CG+P Y APE+ S K Y+ V
Sbjct: 241 IHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEV 300
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
D WS GV++Y +++G PF N + E +L R P + +D ++L+ K + + Q
Sbjct: 301 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVIN-PQ 359
Query: 382 RLGNLQNGSED 392
R +L N +D
Sbjct: 360 RRSSLDNIMKD 370
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 143 bits (360), Expect = 6e-34
Identities = 80/251 (31%), Positives = 137/251 (53%), Gaps = 5/251 (1%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++L+T+G G+F +V L + G A+ + + + M + HP
Sbjct: 170 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQL-DHPN 228
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I++++ + Q L+++++Y GGE+F L R A+ ++ A++YLHSK I
Sbjct: 229 IVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNI 288
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAK--YVPDVTYTLCGTPDYIAPEVVSTKPYN-KSV 321
I+RDLK EN+LLD++ +IK+ DFGF+ + + T CG+P Y APE+ S K Y+ V
Sbjct: 289 IHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEV 348
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
D WS GV++Y +++G PF N + E +L R P + +D ++L+ K + + Q
Sbjct: 349 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVIN-PQ 407
Query: 382 RLGNLQNGSED 392
R +L N +D
Sbjct: 408 RRSSLDNIMKD 418
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 142 bits (359), Expect = 8e-34
Identities = 81/271 (29%), Positives = 133/271 (48%), Gaps = 13/271 (4%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
RV G Y L D TLG G+FG+V + + G A+ E
Sbjct: 12 RVKIGHYILGD-----TLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRRE 66
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
L + HP II+++ +FM+M+Y+ GGELF + K+ R ++ ++
Sbjct: 67 IQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQIL 126
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEV 311
++Y H +++RDLKPEN+LLD + + K+ DFG + + D + T CG+P+Y APEV
Sbjct: 127 SGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEV 186
Query: 312 VSTKPY-NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDL 370
+S + Y VD WS GV++Y +L G PF D + ++ I + P + + L
Sbjct: 187 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISL 246
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
+ ++ D +R +D++ H WF +
Sbjct: 247 LKHMLQVDPMKRA-----SIKDIREHEWFKQ 272
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 142 bits (357), Expect = 1e-33
Identities = 83/271 (30%), Positives = 130/271 (47%), Gaps = 13/271 (4%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
RV G Y L D TLG G+FG+V + G A+ E
Sbjct: 10 RVKIGHYVLGD-----TLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKRE 64
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
L + HP II+++ FM+M+Y+ GGELF + K R A+ ++
Sbjct: 65 IQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQIL 124
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEV 311
A++Y H +++RDLKPEN+LLD + + K+ DFG + + D + T CG+P+Y APEV
Sbjct: 125 SAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEV 184
Query: 312 VSTKPY-NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDL 370
+S + Y VD WS GV++Y +L G PF D + ++ I P + + L
Sbjct: 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL 244
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWFSE 401
+ ++ D +R +D++ H WF +
Sbjct: 245 LMHMLQVDPLKRA-----TIKDIREHEWFKQ 270
>Hs21166359 [T] KOG0986 G protein-coupled receptor kinase
Length = 553
Score = 142 bits (357), Expect = 1e-33
Identities = 102/323 (31%), Positives = 159/323 (48%), Gaps = 17/323 (5%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
F R LG G FG V V+ + G+ YA + E+ +L VS PF
Sbjct: 191 FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSPF 250
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGEL-FSLLRKSQR-FPNPVAKFYAAEVCLALEYLHSK 262
I+ + F+ L ++M + GG+L F + R FY+A++ + +LH
Sbjct: 251 IVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGMLHLHEL 310
Query: 263 GIIYRDLKPENILLDKNGHIKLTDFGFA---KYVPDVTYTLCGTPDYIAPEVVSTK-PYN 318
GI+YRD+KPEN+LLD G+ +L+D G A K +T GT Y+APE++ K Y+
Sbjct: 311 GIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQR-AGTNGYMAPEILMEKVSYS 369
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENI----LNAPVRFP-PFFHSDAQDLISK 373
VDW++ G IYEM+AG TPF D + E++ L V+F F +A+D+
Sbjct: 370 YPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRL 429
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEP-PIQAGQGDTSQYDR 432
+ + QRLG+ + S+D + H +F + + +L IE P+ P P D ++ D
Sbjct: 430 FLAKKPEQRLGSREK-SDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYAKDIAEIDD 488
Query: 433 YPEEEVNYGIQGEDPYHSIFTNF 455
+ E G++ +D F NF
Sbjct: 489 FSEVR---GVEFDDKDKQFFKNF 508
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 141 bits (356), Expect = 2e-33
Identities = 78/255 (30%), Positives = 140/255 (54%), Gaps = 11/255 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
++++L+T+G G+F +V L R G+ A+ + + R ++ +++HP
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVR-IMKVLNHP 77
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I++++ + + L+++M+Y GGE+F L R A+ ++ A++Y H K
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 137
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY-----TLCGTPDYIAPEVVSTKPYN 318
I++RDLK EN+LLD + +IK+ DFGF+ + T+ T CG+P Y APE+ K Y+
Sbjct: 138 IVHRDLKAENLLLDADMNIKIADFGFSN---EFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 319 -KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
VD WS GV++Y +++G PF N + E +L R P + +D ++L+ K +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 254
Query: 378 DLSQRLGNLQNGSED 392
+ S+R G L+ +D
Sbjct: 255 NPSKR-GTLEQIMKD 268
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 141 bits (356), Expect = 2e-33
Identities = 78/255 (30%), Positives = 140/255 (54%), Gaps = 11/255 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
++++L+T+G G+F +V L R G+ A+ + + R ++ +++HP
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVR-IMKVLNHP 77
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I++++ + + L+++M+Y GGE+F L R A+ ++ A++Y H K
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 137
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY-----TLCGTPDYIAPEVVSTKPYN 318
I++RDLK EN+LLD + +IK+ DFGF+ + T+ T CG+P Y APE+ K Y+
Sbjct: 138 IVHRDLKAENLLLDADMNIKIADFGFSN---EFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 319 -KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
VD WS GV++Y +++G PF N + E +L R P + +D ++L+ K +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 254
Query: 378 DLSQRLGNLQNGSED 392
+ S+R G L+ +D
Sbjct: 255 NPSKR-GTLEQIMKD 268
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 141 bits (356), Expect = 2e-33
Identities = 78/255 (30%), Positives = 140/255 (54%), Gaps = 11/255 (4%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
++++L+T+G G+F +V L R G+ A+ + + R ++ +++HP
Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVR-IMKVLNHP 110
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I++++ + + L+++M+Y GGE+F L R A+ ++ A++Y H K
Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 170
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY-----TLCGTPDYIAPEVVSTKPYN 318
I++RDLK EN+LLD + +IK+ DFGF+ + T+ T CG+P Y APE+ K Y+
Sbjct: 171 IVHRDLKAENLLLDADMNIKIADFGFSN---EFTFGNKLDTFCGSPPYAAPELFQGKKYD 227
Query: 319 -KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
VD WS GV++Y +++G PF N + E +L R P + +D ++L+ K +
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 287
Query: 378 DLSQRLGNLQNGSED 392
+ S+R G L+ +D
Sbjct: 288 NPSKR-GTLEQIMKD 301
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 141 bits (355), Expect = 2e-33
Identities = 79/267 (29%), Positives = 138/267 (51%), Gaps = 11/267 (4%)
Query: 138 GKYALY--DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERN 195
G++A Y +++ +TLG G G V L G+ A+ + E
Sbjct: 42 GRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIA 100
Query: 196 MLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLA 255
+L ++ HP ++++ +++ + L+++++++ GGELF L K R A+ + ++ A
Sbjct: 101 ILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSA 160
Query: 256 LEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFA--KYVPDVTYTLCGTPDYIAPEVVS 313
L++ HS I +RDLKPEN+LLD+ +I++ DFG A + + T CG+P Y PEV+
Sbjct: 161 LDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIK 220
Query: 314 TKPYN-KSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLIS 372
+ Y+ + D WS GV+++ +L G PF D N + E + P F D Q L+
Sbjct: 221 GEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLR 280
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWF 399
+I + +RL E ++ HPW+
Sbjct: 281 GMIEVEPEKRL-----SLEQIQKHPWY 302
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 140 bits (354), Expect = 3e-33
Identities = 79/252 (31%), Positives = 139/252 (54%), Gaps = 5/252 (1%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
++++ +T+G G+F +V L R GR A+ + + R ++ I++HP
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVR-IMKILNHP 117
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I++++ + + L+++M+Y GGE+F L R A+ ++ A++Y H K
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAK--YVPDVTYTLCGTPDYIAPEVVSTKPYN-KS 320
I++RDLK EN+LLD + +IK+ DFGF+ V + T CG+P Y APE+ K Y+
Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 237
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VD WS GV++Y +++G PF N + E +L R P + +D ++L+ KL+ +
Sbjct: 238 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPI 297
Query: 381 QRLGNLQNGSED 392
+R G+L+ +D
Sbjct: 298 KR-GSLEQIMKD 308
>CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 392
Score = 140 bits (354), Expect = 3e-33
Identities = 83/273 (30%), Positives = 140/273 (50%), Gaps = 9/273 (3%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHN---GRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
DF+IL+ +G+G++G V VR + YAM + E +L+ +
Sbjct: 28 DFEILKHIGSGAYGEVAAVRKLNGCDTETIYAMKVMEKRRMSKHK--DMVEHEWKILTTI 85
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
+PF ++M +FQ + L +M + GG++ +++ +++ A FY E+ + YLH
Sbjct: 86 HNPFFMKMSYSFQTKRHLVFVMPFAGGGDMLTMM-ENECLIEESAHFYLCELVEGIGYLH 144
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPY 317
K I++RD+K EN+L+ +GH+ +TD+G + D + GT +APEV K Y
Sbjct: 145 EKHIVHRDVKLENLLIGNDGHLMITDYGLSATGCDAEDAIQGVIGTRHTMAPEVHLEKKY 204
Query: 318 NKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITR 377
S DWW+ G+ +M + F +++ + ++ R P + ++KLI R
Sbjct: 205 GTSCDWWAVGITYCDMRSDKAVFDGADSKEYSDSTAKKRPRLPKVLSPRERGFVNKLIVR 264
Query: 378 DLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCK 410
D +QRLGN +G+ VK H F VVWE +L K
Sbjct: 265 DPTQRLGNGPDGTATVKAHDMFKGVVWEDVLAK 297
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 140 bits (353), Expect = 4e-33
Identities = 85/257 (33%), Positives = 136/257 (52%), Gaps = 10/257 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
++ L TLG G++G+V R + +GR A+ H E ++S ++HP
Sbjct: 53 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
II + F++S ++ ++M+Y G+L+ + + Q+ A+ + ++ A+ Y H +
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPY-NKSV 321
++RDLK ENILLD NG+IK+ DFG + + T CG+P Y +PE+V+ KPY V
Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
D WS GVL+Y ++ G PF + + I N R PP SDA LI L+ + ++
Sbjct: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWLLMVNPTR 290
Query: 382 RLGNLQNGSEDVKNHPW 398
R EDV +H W
Sbjct: 291 RA-----TLEDVASHWW 302
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 140 bits (352), Expect = 5e-33
Identities = 80/267 (29%), Positives = 133/267 (48%), Gaps = 9/267 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+ I RT+G G+F V L R A+ + E ++ + HP
Sbjct: 141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNL-QKVYREVEIMKRLKHPH 199
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
II+++ + ++++ +Y GE+F + K R A+F ++ A+EY H KGI
Sbjct: 200 IIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGI 259
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPY-NKSV 321
++RDLK EN+LLD N +IK+ DFGF+ + ++ T CG+P Y APEV K Y +
Sbjct: 260 VHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEI 319
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
D WS GV++Y ++ G PF S + +L+ R P F S+ + LI +++ + ++
Sbjct: 320 DIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTR 379
Query: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLL 408
R + +K H W + E +L
Sbjct: 380 RY-----TIDQIKRHRWMCPELLEHVL 401
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 139 bits (351), Expect = 7e-33
Identities = 89/309 (28%), Positives = 152/309 (48%), Gaps = 49/309 (15%)
Query: 128 TSTLKARVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXX------------ 175
+S K+R T G + L +TLG GS GRV L ++ G+ A+
Sbjct: 69 SSKRKSRDTVGPWKLG-----KTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSN 123
Query: 176 -------------XXXXXXXXXXXXEHTNDERN----------MLSIVSHPFIIRMWGTF 212
EH+N + ++ ++SH ++ ++ +
Sbjct: 124 NGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVW 183
Query: 213 QDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIYRDLKPE 272
++ +L+++++Y++GGELF L + P A Y ++ + Y HS I +RDLKPE
Sbjct: 184 ENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPE 243
Query: 273 NILLD-KNGHIKLTDFGFAKY-VPD-VTYTLCGTPDYIAPEVVSTKPYNKS-VDWWSFGV 328
N+LLD KN IK+ DFG A +P+ + T CG+P Y +PE+V +PY+ D WS G+
Sbjct: 244 NLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGI 303
Query: 329 LIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQRLGNLQN 388
+++ +L G+ PF D N K + + + P S+A+DLISK++ D +R+
Sbjct: 304 VLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRI----- 358
Query: 389 GSEDVKNHP 397
++++ HP
Sbjct: 359 TTQEILKHP 367
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 139 bits (350), Expect = 9e-33
Identities = 81/275 (29%), Positives = 138/275 (49%), Gaps = 22/275 (8%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTND----ERNMLSIV 200
++I+RTLG+G+F V L ++G++YA+ + + E ++L +
Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
HP +++ F++ +LF++M+Y+EGG+L L + K ++ L +LH
Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH 286
Query: 261 SKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDV---TYTLCGTPDYIAPEVVSTK-- 315
+G+ +RD+KPENIL+ + H+K++DFG AK + T CGT Y+APEV+ +K
Sbjct: 287 KQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNV 346
Query: 316 ----PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQ--- 368
Y+ VD WS G ++Y ML PF S+ K E I P ++
Sbjct: 347 NLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEG 406
Query: 369 -DLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEV 402
DLI++++ + +R+ + HPWF V
Sbjct: 407 IDLINRMLEINPEKRI-----SESEALQHPWFYTV 436
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 139 bits (350), Expect = 9e-33
Identities = 77/259 (29%), Positives = 131/259 (49%), Gaps = 9/259 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ +TLG G G V GR A+ + E ++ ++ HP
Sbjct: 47 YKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVL-QKVEREIAIMKLIEHPH 105
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++ ++ +++ + L+++++++ GGELF L + R + A+ + ++ AL++ H+ I
Sbjct: 106 VLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNI 165
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVPD--VTYTLCGTPDYIAPEVVSTKPYN-KSV 321
+RDLKPEN+LLD+ +IK+ DFG A + + T CG+P Y PEV+ + Y+ +
Sbjct: 166 CHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKA 225
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
D WS GV++Y +L G PF D N E + P F +D Q L+ +I D +
Sbjct: 226 DVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLLRAMIEVDPGK 285
Query: 382 RLGNLQNGSEDVKNHPWFS 400
R DV HPW S
Sbjct: 286 RY-----SLADVFKHPWVS 299
>At2g20040 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 261
Score = 139 bits (350), Expect = 9e-33
Identities = 66/175 (37%), Positives = 107/175 (60%), Gaps = 4/175 (2%)
Query: 246 KFYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVP-DVTYTLCGTP 304
+F + A+E +H I++R PE ++LD++G++++ DF FAK + + T+T+CG
Sbjct: 50 RFITGSLVSAIEDIHKNEILFRGSSPELLMLDQSGYLQIVDFRFAKKLSGERTFTICGNA 109
Query: 305 DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF--YDSNTIKTYENILNAPVRFPPF 362
DY+APE+V K + + DWW+ GVLIY ML G PF + + + T++ I + FP
Sbjct: 110 DYLAPEIVQGKGHGYAADWWALGVLIYYMLEGEMPFGSWRESELDTFQKIAKGQLTFPRV 169
Query: 363 FHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYE 417
S+A+DLI+KL+ D + R G+ Q G E +K HPWF+ + WE + + + P E
Sbjct: 170 LSSEAEDLITKLLEVDENLRFGS-QGGPESIKKHPWFNGLKWEAISNREFQVPQE 223
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 139 bits (349), Expect = 1e-32
Identities = 87/267 (32%), Positives = 136/267 (50%), Gaps = 18/267 (6%)
Query: 140 YALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSI 199
Y YD +G G F R V+ N+ G YA E +
Sbjct: 41 YTRYD-----CIGEGGFARCFRVKDNY-GNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQS 94
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
+SHP I+ F+DS +++I++ E L LLRK ++ P ++ ++ AL+Y+
Sbjct: 95 MSHPNIVGFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYM 154
Query: 260 HSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPD---VTYTLCGTPDYIAPEVV--ST 314
H K +I+RDLK NI+LD++ ++K+ DFG A + D T+CGTP+YIAPE++ S
Sbjct: 155 HKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSK 214
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPP--FFHSDAQDLIS 372
+ ++ VD WS GV++Y +L G PF D Y I FP ++A+DLIS
Sbjct: 215 EGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLIS 274
Query: 373 KLITRDLSQRLGNLQNGSEDVKNHPWF 399
L+T D S ++ +D+ +H +F
Sbjct: 275 SLLTHDPS-----IRPSIDDIVDHEFF 296
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 139 bits (349), Expect = 1e-32
Identities = 78/252 (30%), Positives = 137/252 (53%), Gaps = 5/252 (1%)
Query: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHP 203
++++L+T+G G+F +V L R GR A+ + + R ++ I++HP
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVR-IMKILNHP 113
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I++++ + + L++IM+Y GG++F L R A+ ++ A++Y H K
Sbjct: 114 NIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAK--YVPDVTYTLCGTPDYIAPEVVSTKPYN-KS 320
I++RDLK EN+LLD + +IK+ DFGF+ V T CG+P Y APE+ K Y+
Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPE 233
Query: 321 VDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLS 380
VD WS GV++Y +++G PF N + E +L R P + +D ++L+ + + +
Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPI 293
Query: 381 QRLGNLQNGSED 392
+R G L+ +D
Sbjct: 294 KR-GTLEQIMKD 304
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 139 bits (349), Expect = 1e-32
Identities = 73/237 (30%), Positives = 125/237 (51%), Gaps = 6/237 (2%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ RTLG G+FG+V + +G +A+ E L ++ HP
Sbjct: 20 YELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPH 79
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
I+R+ ++ M+M+ + GGELF + + + + ++ + Y HSKG+
Sbjct: 80 IVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGV 139
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFA---KYVPD--VTYTLCGTPDYIAPEVVSTKPYNK 319
+RDLK EN+LLD GHIK+TDFG + ++ D + +T CG+P+Y+APEV++ + Y+
Sbjct: 140 FHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDG 199
Query: 320 SV-DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLI 375
+ D WS GV++Y +L G PF D N Y+ I P + A+ +I +++
Sbjct: 200 AASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRML 256
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 138 bits (347), Expect = 2e-32
Identities = 91/290 (31%), Positives = 151/290 (51%), Gaps = 33/290 (11%)
Query: 132 KARVTSGKYALYDFQILRTLGTGSFGRVHL-----VRSNHNGRF-YAMXXXXXXXXXXXX 185
+ VT G Y L TLG G FG+V L ++ N F +
Sbjct: 33 RKHVTFGPYILGS-----TLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSI 87
Query: 186 XXEHTND-----ERNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRF 240
++ + E N L +SHP I+++ Q+S+ + ++++Y GGE + ++K +R
Sbjct: 88 SNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRL 147
Query: 241 PNPVAKFYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYV---PDVT 297
A +++ + Y+HSKG+++RDLK EN+LLDKN ++ +TDFGF ++
Sbjct: 148 KEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELM 207
Query: 298 YTLCGTPDYIAPE-VVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYD-------SNTIKT 348
T CG+P Y APE V+S +PY + D WS GV++Y +LAGY P+ D S+ +
Sbjct: 208 KTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRL 267
Query: 349 YENILNAPVRFPPFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPW 398
Y I + P++FP + +DL+ +++ D +R+ NL + +K H W
Sbjct: 268 YNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRI-NL----KQIKKHEW 312
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 138 bits (347), Expect = 2e-32
Identities = 84/268 (31%), Positives = 141/268 (52%), Gaps = 19/268 (7%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHT-NDERNMLSIVSHP 203
+++ RT+G G+F V R YA+ EH +E ++L V HP
Sbjct: 46 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK---EHMIQNEVSILRRVKHP 102
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
I+ + +L+++M+ ++GG+LF + + ++ A + A++YLHS
Sbjct: 103 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLN 162
Query: 264 IIYRDLKPENILL----DKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNK 319
I++RD+KPEN+L+ D + +KL DFG A V YT+CGTP Y+APE+++ Y
Sbjct: 163 IVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGL 222
Query: 320 SVDWWSFGVLIYEMLAGYTPFYDSNTIK--TYENILNAPVRFP-PFFHS---DAQDLISK 373
VD W+ GV+ Y +L G+ PF S + ++ IL V FP P++ + A++LI+
Sbjct: 223 KVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITM 282
Query: 374 LITRDLSQRLGNLQNGSEDVKNHPWFSE 401
++ D+ QR +Q V HPW ++
Sbjct: 283 MLLVDVDQRFSAVQ-----VLEHPWVND 305
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 137 bits (346), Expect = 3e-32
Identities = 97/318 (30%), Positives = 156/318 (48%), Gaps = 38/318 (11%)
Query: 150 TLGTGSFGRVHL-----VRSNHNGRFYAMXXXXXXXXXXXXXXE-HTNDERNMLSIVSHP 203
TLG G FG+V L SN + A+ E E N L ++HP
Sbjct: 51 TLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHP 110
Query: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263
II + Q+S+ + ++++++ GGE + +++ +R A A++ + Y+H KG
Sbjct: 111 NIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKG 170
Query: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYV---PDVTYTLCGTPDYIAPE-VVSTKPYN- 318
+++RDLK EN+LLDK+ ++ +TDFGF ++ T CG+P Y APE VVSTK Y
Sbjct: 171 LVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEA 230
Query: 319 KSVDWWSFGVLIYEMLAGYTPFYDSNTIKT-------YENILNAPVRFPPFFHSDAQDLI 371
+ D WS GV++Y MLAGY P+ D + T Y+ I P++FP + +DL+
Sbjct: 231 RKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLL 290
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPW---------FSEVVWEKLLCKNIETPYEPPIQA 422
+++ + +R+ NLQ +K H W W++ L K E P
Sbjct: 291 RRILVPNPRRRI-NLQT----IKRHVWLKPHEAFLSIQPNYWDEHLQK------ERPKPP 339
Query: 423 GQGDTSQYDRYPEEEVNY 440
+GD ++ Y +Y
Sbjct: 340 NKGDVGRHSTYSSSASSY 357
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 137 bits (346), Expect = 3e-32
Identities = 93/357 (26%), Positives = 155/357 (43%), Gaps = 72/357 (20%)
Query: 134 RVTSGKYALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDE 193
R+ + +L DF ++ +G G+FG V LV+ G+ YAM H E
Sbjct: 341 RLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAE 400
Query: 194 RNMLSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 253
R++L+ P+++ ++ +FQD+Q L++IM+++ GG+L ++L + Q F V +FY AE
Sbjct: 401 RDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECI 460
Query: 254 LALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFA----------------------- 290
LA+E +H G I+RD+KP+NIL+D GHIKL+DFG +
Sbjct: 461 LAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATN 520
Query: 291 ------KYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSN 344
Y + T T + + T + + W + TP Y +
Sbjct: 521 GISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAP 580
Query: 345 TIKTYEN-------------ILNAPVRFPPFFHSDAQD---------------------- 369
I Y+ + + +PPF Q+
Sbjct: 581 EIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISY 640
Query: 370 ----LISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQA 422
LI +L+T QRLG G++++K+HP+F V W + + +E PY P + +
Sbjct: 641 EAEDLIRRLLTH-ADQRLGR-HGGADEIKSHPFFRGVDWNTI--RQVEAPYIPKLSS 693
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 137 bits (346), Expect = 3e-32
Identities = 86/271 (31%), Positives = 141/271 (51%), Gaps = 14/271 (5%)
Query: 138 GKYA-LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNM 196
GK A LYD +TLG G F V L R G A+ H E
Sbjct: 10 GKIAGLYDLD--KTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATG-HLFQEVRC 66
Query: 197 LSIVSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNP-VAKFYAAEVCLA 255
+ +V HP I+R++ +L++I++ + G++F + K + N + K Y A++ A
Sbjct: 67 MKLVQHPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHA 126
Query: 256 LEYLHSKGIIYRDLKPENILL-DKNGHIKLTDFGFA-KYVPDVTYTL-CGTPDYIAPEVV 312
+ Y H +++RDLKPEN++ +K G +KLTDFGF+ K+ P T CG+ Y APE++
Sbjct: 127 ISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEIL 186
Query: 313 STKPYNK-SVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLI 371
Y+ +VD WS GV+++ ++ G PF ++N +T I++ P + +DLI
Sbjct: 187 LGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLI 246
Query: 372 SKLITRDLSQRLGNLQNGSEDVKNHPWFSEV 402
++++ RD +R E+++NHPW V
Sbjct: 247 TRMLQRDPKRRA-----SLEEIENHPWLQGV 272
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 137 bits (345), Expect = 3e-32
Identities = 62/164 (37%), Positives = 101/164 (60%), Gaps = 4/164 (2%)
Query: 200 VSHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 259
++HP I+++ T++D +++++M+ + GGELF + + + A ++ A++Y+
Sbjct: 100 LTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYM 159
Query: 260 HSKGIIYRDLKPENILL---DKNGHIKLTDFGFAKYVPD-VTYTLCGTPDYIAPEVVSTK 315
H +G+++RDLKPEN+L D + I ++DFG +K + T CGTP Y+APEV++ K
Sbjct: 160 HEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQK 219
Query: 316 PYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRF 359
PY K+VD WS GV+ Y +L GY PFYD N + IL F
Sbjct: 220 PYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEF 263
>Hs22042851 [T] KOG0986 G protein-coupled receptor kinase
Length = 266
Score = 137 bits (344), Expect = 4e-32
Identities = 75/185 (40%), Positives = 104/185 (55%), Gaps = 6/185 (3%)
Query: 240 FPNPVAKFYAAEVCLALEYLHSKGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYT 299
F A FYAAE+C LE L + I+YRDLKPENILLD GHI+++D G A +P+
Sbjct: 18 FDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRV 77
Query: 300 --LCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYE----NIL 353
GT Y+APEVV+ + Y S DWW G LIYEM+ G++PF +E I
Sbjct: 78 RGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIK 137
Query: 354 NAPVRFPPFFHSDAQDLISKLITRDLSQRLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIE 413
N + F DA+ + L+T++ S+RLG G+ VK HP F ++ + +L +E
Sbjct: 138 NDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLE 197
Query: 414 TPYEP 418
P+ P
Sbjct: 198 PPFCP 202
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 137 bits (344), Expect = 4e-32
Identities = 93/269 (34%), Positives = 132/269 (48%), Gaps = 21/269 (7%)
Query: 141 ALYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIV 200
A YD + L +GTGSF RV V + +A+ E E ++L V
Sbjct: 61 ARYDIKAL--IGTGSFSRVVRVEQKTTKKPFAIKVMETREREGR---EACVSELSVLRRV 115
Query: 201 SHPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 260
SH +I+++ F+ Q++M+M+ GGELF L F A V + YLH
Sbjct: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLH 175
Query: 261 SKGIIYRDLKPENILLDKNGH---IKLTDFGFA---KYVPDVTY-TLCGTPDYIAPEVVS 313
+ I +R+LKPEN+L G I +TDFG A K D T TLCGTP+YIAPEV+
Sbjct: 176 ALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
Query: 314 TKPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFP----PFFHSDAQD 369
KPY +VD W+ GV+ Y +L+G+ PF D + + Y IL + P A+D
Sbjct: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
Query: 370 LISKLITRDLSQRLGNLQNGSEDVKNHPW 398
I KL+ + R+ + +HPW
Sbjct: 296 FIDKLLILEAGHRM-----SAGQALDHPW 319
>CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 722
Score = 137 bits (344), Expect = 4e-32
Identities = 98/312 (31%), Positives = 155/312 (49%), Gaps = 33/312 (10%)
Query: 145 FQIL--RTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXX-XEHTNDERNMLSIVS 201
+Q+L +TLG+G FG V+ H+G+ A+ E E +L
Sbjct: 424 YQVLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTC 483
Query: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCLALEYLH 260
HP I+ + + ++F++M+ + G L +L + R + KF ++ AL+YLH
Sbjct: 484 HPGIVCLEFMCETKDKIFVVMEKMNGDMLEMILSQELGRLNSRATKFLLVQILCALKYLH 543
Query: 261 SKGIIYRDLKPENILLDKNG----HIKLTDFGFAKYVPDVTY--TLCGTPDYIAPEVVST 314
+GI + DLKPEN+LL G K+ DFG+A+++P+ + T+ GTP Y+ PEV+
Sbjct: 544 DQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYARFIPESQFRKTVVGTPAYLPPEVLQR 603
Query: 315 KPYNKSVDWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSD----AQDL 370
K YNKS+D WS GV+IY L+G PF + I E I NA FP S+ A DL
Sbjct: 604 KGYNKSLDMWSVGVIIYVTLSGTFPFNEGEEIS--EQIQNASFMFPTEPWSEVEPLAVDL 661
Query: 371 ISKLITRDLSQRLGNLQNGSEDVKNHPWF-SEVVWEKLLCKNIETPYEPPIQAGQGDTSQ 429
I KL+ ++ R+ E +H W E ++ L +++E P +
Sbjct: 662 IQKLLKVEIEARM-----SIEQCLDHGWLKGEQLYRDL--RDLEVRLNTP---------R 705
Query: 430 YDRYPEEEVNYG 441
Y P++++ YG
Sbjct: 706 YLTSPQDDILYG 717
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 137 bits (344), Expect = 4e-32
Identities = 78/257 (30%), Positives = 130/257 (50%), Gaps = 9/257 (3%)
Query: 145 FQILRTLGTGSFGRVHLVRSNHNGRFYAMXXXXXXXXXXXXXXEHTNDERNMLSIVSHPF 204
+++ +TLG G G V L G+ A+ + E ++ ++ HP
Sbjct: 18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMK-VEREIAIMKLIDHPH 76
Query: 205 IIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGI 264
++ + +++ + L++I++++ GGELF L K R A+ + ++ AL++ HS I
Sbjct: 77 VLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 136
Query: 265 IYRDLKPENILLDKNGHIKLTDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYN-KSV 321
+RDLKPEN+LLD+ +IK+ DFG A P + T CG+P Y PEV+ + Y+ +
Sbjct: 137 CHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKA 196
Query: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
D WS GV++Y +L G PF D N + E + P F D Q L+ +I + +
Sbjct: 197 DVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDR 256
Query: 382 RLGNLQNGSEDVKNHPW 398
RL ++ HPW
Sbjct: 257 RL-----TLAEINRHPW 268
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,415,720
Number of Sequences: 60738
Number of extensions: 1069079
Number of successful extensions: 7828
Number of sequences better than 1.0e-05: 1756
Number of HSP's better than 0.0 without gapping: 679
Number of HSP's successfully gapped in prelim test: 1077
Number of HSP's that attempted gapping in prelim test: 3829
Number of HSP's gapped (non-prelim): 2048
length of query: 455
length of database: 30,389,216
effective HSP length: 110
effective length of query: 345
effective length of database: 23,708,036
effective search space: 8179272420
effective search space used: 8179272420
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)