ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1775 good R KOG2816 General function prediction only Predicted transporter ADD1 (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1775 629695 627836 -620
(620 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL163c [R] KOG2816 Predicted transporter ADD1 (major facilitato... 319 9e-87
SPAC14C4.07 [R] KOG2816 Predicted transporter ADD1 (major facili... 53 1e-06
Hs18087847 [R] KOG2816 Predicted transporter ADD1 (major facilit... 53 2e-06
>YJL163c [R] KOG2816 Predicted transporter ADD1 (major facilitator
superfamily)
Length = 555
Score = 319 bits (817), Expect = 9e-87
Identities = 180/488 (36%), Positives = 272/488 (54%), Gaps = 23/488 (4%)
Query: 84 LVYLCVILVSISLTDTLVLAPFTLLSMKKICESIAQSNNEWSIDGSPVCDPSKVQEKLSG 143
LV + I SIS+T T+ L M K+ E I+ N + D VQ +S
Sbjct: 84 LVMIICIAESISMTATIPLV------MDKVAEGISDENGHY--------DSVAVQTIVSS 129
Query: 144 LTSIIFLINGVAGTLLSGKLGELSDRFGRVPIFVYVGSIKAIGLVIMLYVYHTKNVFHTS 203
++S +I G ++GK GELSDR GRV +F Y+ I+ IGL+ ++ +K +H
Sbjct: 130 ISSSTMMIAGAISIFMAGKWGELSDRIGRVRVFKYMSGIRVIGLLTHVFTLSSKMKYHKW 189
Query: 204 LFIIGQC-VPSFGGSMITLIANGNSYISDIVEPELRPIYISFVMSSIYGSIGLGPFLSSI 262
++ C VPSFGG + L+ANGNSY+SDIV+ E R + I +MS IY ++G+GP S
Sbjct: 190 AIVLTACIVPSFGG-LFALVANGNSYVSDIVKTEHRMVTIGIMMSCIYATMGVGPMFGSF 248
Query: 263 LVKLSHGDNFVPIWVALGLAVSLTLVCAFLMSESRHEMARLKSQTKFLRRRESINSARSR 322
LVK +HG+ F+PI+ ++ + ++C +M E RHE SQ+ + +RRE + S
Sbjct: 249 LVKWTHGNGFIPIYTSIAFVILALIICETIMVEPRHETQMAHSQSTYTKRREKLRS---- 304
Query: 323 QSDMAGGAN-RSYTVLKYTALQFFDFLSPVRNLWIAPTAAGSLVPRYMVLLLVGIDIMFV 381
QS N +S T K+ ++ D L+PV+ LW+ P +AGSLVPR+ V+LL+ +DI+FV
Sbjct: 305 QSGSDDARNYQSVTYGKFQIMRLMDLLAPVKKLWLKPDSAGSLVPRHTVILLIVLDILFV 364
Query: 382 ISTAASIPAIVLAFVFMFGWSSEQLGYFVSXXXXXXXXXXXXXXXXXXXXXKKRFKTLSK 441
T + +PA++L + + W + +LGYF+S K+ ++ L+
Sbjct: 365 CGTTSCMPALILFSTYEYKWHAVELGYFISILGIGRGVVLLVVSPTLLYTLKRIYQHLNH 424
Query: 442 SVDHTDM--XXXXXXXXXXXXXXXXXXXXXXESAAYVYVLLQILGSMLSPTVQSTVIKYG 499
S+D D+ ++ ++ LLQ L + SPT+QS +IKY
Sbjct: 425 SIDKIDIFCIQFSMIVITLSLFVMIRFGEKTPTSMIIFALLQALSAFCSPTLQSGIIKYT 484
Query: 500 SKSSTGELFGAMALIRSCAMMVMPSLFLKLYSRTVNLDPLFFVYIPLVLCIGACLMTAFL 559
SK TGE+FGAMAL+RSC M+V+P + LKLY TV+++P F+YIP I A L+T FL
Sbjct: 485 SKKHTGEMFGAMALVRSCVMLVIPPILLKLYGSTVSVNPSLFMYIPFSTSIVAILLTFFL 544
Query: 560 KIVDDPEL 567
+I +P L
Sbjct: 545 RIYKNPPL 552
>SPAC14C4.07 [R] KOG2816 Predicted transporter ADD1 (major facilitator
superfamily)
Length = 644
Score = 53.1 bits (126), Expect = 1e-06
Identities = 42/217 (19%), Positives = 90/217 (41%), Gaps = 7/217 (3%)
Query: 100 LVLAPFTLLSMKKICESIAQSNNEWSIDGSPVCDPSKVQEKLSGLTSIIFLINGVAGTLL 159
++ P L +++C + P+C +++ +S + + + G
Sbjct: 144 MIEIPLLFLLRQELCAIHYNLDPTQLSPDDPICRLAEITTGVSKVRAAFGSLAAFLGLFS 203
Query: 160 SGKLGELSDRFGRVPIFVYVGSIKAIGLVIMLYVYHTKNVFHTSLFIIGQCVPSFGGSMI 219
+ G + D +GR + S +G + +LY + H + + GG +
Sbjct: 204 TAYYGTMGDIYGRRLVLFITVSFLLLGDLWLLYQSYAPK--HPYFVLFAAALKGLGGYIS 261
Query: 220 TLIANGNSYISDIVEPELRPIYISFVMSSIYGSIGLGPFLSSILVKLSHGDNFV-----P 274
T++A+ NS+++D + E R Y+ ++ + LGP LS +V+ + +V
Sbjct: 262 TVVASQNSFVADCSKTEFRAWYLGLNFAAYHLGTALGPSLSGFIVQYTPHMYYVFYITST 321
Query: 275 IWVALGLAVSLTLVCAFLMSESRHEMARLKSQTKFLR 311
W+ L V L L + +SES+ + ++ + R
Sbjct: 322 FWIIYLLYVWLILPESLDVSESKEQQNKISGFSSIWR 358
>Hs18087847 [R] KOG2816 Predicted transporter ADD1 (major facilitator
superfamily)
Length = 431
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 28/180 (15%)
Query: 133 DPSKVQEKLSGLTSIIFLINGVAGTLL----SGKLGELSDRFGRVPIFVYVGSIKAIGLV 188
DP+ +++ LTS L V G L+ S LG SD GR P+ V + ++GL+
Sbjct: 72 DPT--MQEVETLTSHWTLYMNVGGFLVGLFSSTLLGAWSDSVGRRPLLV----LASLGLL 125
Query: 189 I--MLYVYHTKNVFHTSLFIIGQCVPSFGGSMITLIANGNSYISDIVEPELRPIYISFVM 246
+ ++ V+ + H F++G+ + + G L+A + ++D+ R +F M
Sbjct: 126 LQALVSVFVVQLQLHVGYFVLGRILCALLGDFGGLLAASFASVADVSSSRSR----TFRM 181
Query: 247 SSIYGSIGLGPFLSSILVKLSHGDNFV-------PIWVALGLAVSLTLVCAFLMSESRHE 299
+ + SIG+ L+S+L G +++ P W+AL L +++TL AF E+ E
Sbjct: 182 ALLEASIGVAGMLASLL-----GGHWLRAQGYANPFWLALALLIAMTLYAAFCFGETLKE 236
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.136 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,035,031
Number of Sequences: 60738
Number of extensions: 1177466
Number of successful extensions: 3246
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3242
Number of HSP's gapped (non-prelim): 4
length of query: 620
length of database: 30,389,216
effective HSP length: 112
effective length of query: 508
effective length of database: 23,586,560
effective search space: 11981972480
effective search space used: 11981972480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)