ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1784 good T KOG2124 Signal transduction mechanisms Glycosylphosphatidylinositol anchor synthesis protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1784 633095 630339 -919
(919 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL165c [T] KOG2124 Glycosylphosphatidylinositol anchor synthesi... 1290 0.0
SPBC839.08c [T] KOG2124 Glycosylphosphatidylinositol anchor synt... 664 0.0
Hs6912500 [T] KOG2124 Glycosylphosphatidylinositol anchor synthe... 557 e-158
At3g01380 [T] KOG2124 Glycosylphosphatidylinositol anchor synthe... 498 e-140
7303806 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesi... 301 2e-81
CE25439 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesi... 280 9e-75
7300908 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesi... 196 2e-49
7301592 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesi... 133 1e-30
7299469 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesi... 124 7e-28
CE18060 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesi... 100 1e-20
YJL062w [T] KOG2125 Glycosylphosphatidylinositol anchor synthesi... 74 8e-13
CE03275 [T] KOG2125 Glycosylphosphatidylinositol anchor synthesi... 69 3e-11
7304201 [T] KOG2125 Glycosylphosphatidylinositol anchor synthesi... 69 3e-11
At2g22530 [T] KOG2125 Glycosylphosphatidylinositol anchor synthe... 60 1e-08
SPAC13G6.03 [T] KOG2125 Glycosylphosphatidylinositol anchor synt... 56 2e-07
YLL031c [T] KOG2126 Glycosylphosphatidylinositol anchor synthesi... 56 3e-07
>YKL165c [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 919
Score = 1290 bits (3339), Expect = 0.0
Identities = 626/909 (68%), Positives = 747/909 (81%), Gaps = 3/909 (0%)
Query: 1 MWSRHRLYFIVAGVLFHLFYLWSIFDIYFVSPLVHGMKQHQSTDEAPAKRLFLIVGDGLR 60
MW++ R + GVLFHLFYLWSIFDIYF+SPLVHGM +QST PAKRLFLIVGDGLR
Sbjct: 1 MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60
Query: 61 ADTTFDKILHPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFYEDVS 120
ADTTFDK+ HPV+G+ ++LAP+IR LV N ATYG+SHTRMPTESRPGHVAMIAGFYEDVS
Sbjct: 61 ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120
Query: 121 AVTKGWQENPVDFDSFFNQSKHTYSFGSPDILPMFKDGAT-PNKVDAWMYGHEFEDFTQS 179
AVTKGW+ NPV+FDSFFNQS HTYSFGSPDILPMFKDGA+ PNKVD WMY H FEDFTQS
Sbjct: 121 AVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQS 180
Query: 180 SIELDAFVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDN 239
SIELDAFVFRH+ +LF+N+ N TL+ EI+QDGNVFFLHLLGCDTAGHSYRPYSAEYYDN
Sbjct: 181 SIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDN 240
Query: 240 VKYIDKEVKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGIN 299
VKYID ++ +L++KV++FF D+ TAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAG+N
Sbjct: 241 VKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLN 300
Query: 300 KPVKNQAPIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGELPLNFIDAP 359
KPV N P+ DNYTENW L+ IKRNDV QADIASLMSYLIG NYP NSVGELP+ +ID
Sbjct: 301 KPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGK 360
Query: 360 EDKKLNALFNNAKAILEQYLVKEQEIIASQFVYKEYEAFVEIPYQEYLQQIESLIERIAK 419
E KL AL+NNA++ILEQYLVK+ E+I SQF YKEY FVE + YL++IE+LI+RI++
Sbjct: 361 ESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISE 420
Query: 420 GENELEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIVYSFSIFLRLFIL 479
GEN LE +AI LTEELM++TL+GL YLTTYNWRFIRTIVT GF+GWI +SF IFL+ FIL
Sbjct: 421 GENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFIL 480
Query: 480 NRDYNSHK-SLLNYFIFGSLTIILNYVLYYQKAPFNYYMYLFFPLIFWSEIFTDRVVLDD 538
+ K S L++ +FGS+ I+LN++L+YQ +PFN+YMYL FPL FWS IFT+R VL
Sbjct: 481 ENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRS 540
Query: 539 GVKEFLKGISIPKRIILVSAIILVYESIVYAFFDRWIFSLIFNMLSFYPLICGYRDWKRN 598
G+KEF KG S KR+++ +II VYE IVY FF RW F+LI N+L+FYP ICG R+ N
Sbjct: 541 GIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVN 600
Query: 599 TLWFITGAAISVFTLLDAVKIESLTQINIASGLIVLTALSGFLHLRKQLNSYTTTVFICQ 658
LW IT +S FTL DAVKIE L QI++A LI+L+A + ++NSYT +F Q
Sbjct: 601 ILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQ 660
Query: 659 ILLVILMVLATNKSIVSLQNRTGLPRDAQVAGWVILVVSLLLMPLIHYMKPNNNYKVRML 718
I LV M+ T++S++SLQ R GLPR++QVAGW+I VSL +MP++HY KPNN+YKVR+L
Sbjct: 661 ISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLL 720
Query: 719 IIFLTFAPTFIILTISFESFFYLVFSAYIVQWIEIESKLKE-QTPNTSHYKQLIRVTIIG 777
II+LTFAP+FIILTISFES FY +F++Y+VQWIEIE+K+KE +T ++ Q++RV++IG
Sbjct: 721 IIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIG 780
Query: 778 FFLLQNAFFGTGNVASISSFSLDSVYRLMPIFDPFPMGALLVIKLIIPYIILSAGLGILN 837
FFLLQ AFFGTGNVASISSFSL+SV RL+PIFDPF MGALL++KLIIPY +LS LGILN
Sbjct: 781 FFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILN 840
Query: 838 LKLHIKDYXXXXXXXXXXXXXXXNFFYLLKTEGSWLDIGITISNYCLAILSSLFMLILEI 897
LKL+ KDY NFFYLL+TEGSWLDIGITISNYCLAILSSLFMLILE+
Sbjct: 841 LKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEV 900
Query: 898 VAHVVLKNV 906
+ HV+LKNV
Sbjct: 901 LGHVLLKNV 909
>SPBC839.08c [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 935
Score = 664 bits (1714), Expect = 0.0
Identities = 382/933 (40%), Positives = 557/933 (58%), Gaps = 48/933 (5%)
Query: 10 IVAGVLFHLFYLWSIFDIYFVSPLVHGMKQHQSTDEAPAKRLFLIVGDGLRADTTFDKIL 69
++ G+LFH+ +L SIFDIYFV+PL+HGMKQ+ S EAPAKRLFLIVGDGLR D
Sbjct: 6 LLLGILFHVVFLKSIFDIYFVTPLIHGMKQY-SAGEAPAKRLFLIVGDGLRPDKLLQPHS 64
Query: 70 HPVTGEHD-YLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFYEDVSAVTKGWQE 128
V GE Y AP++R +++N T+GVSHTR+PTESRPGHVA+IAGFYEDVSAVTKGW++
Sbjct: 65 EKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKK 124
Query: 129 NPVDFDSFFNQSKHTYSFGSPDILPMFKDGAT-PNKVDAWMYGHEFEDFTQSSIELDAFV 187
NPV+FDS FNQS+HTYSFGS DILPMF +GA+ P++VD +MY E EDF+ + I LD +V
Sbjct: 125 NPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWV 184
Query: 188 FRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDKEV 247
F + EL + +K L + +D VFFLHLLG DT GH+ P S EY +N++YID ++
Sbjct: 185 FDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKI 244
Query: 248 KLLVEKVHEFF-DDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGINKPVKNQA 306
+ LV+K++ ++ +D ++++FTADHGMS FGSHGDG+ +NTRTP++AWGAGI P +
Sbjct: 245 QELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKN 304
Query: 307 PIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGELPLNFIDAPEDKKLNA 366
D Y+ WNL +IKR D+ QADIA+LMSYL+G N+PVNSVG++PL+++D +K
Sbjct: 305 YGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEV 364
Query: 367 LFNNAKAILEQYLVKEQEIIASQFVYKEYEA---FVEIPYQEYLQQIESLIERIAKGENE 423
NA I EQY +K + ++ Y + E+ Y S+I I GE E
Sbjct: 365 ALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFY----NSVIADIESGEYE 420
Query: 424 LEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIVYSFSIFLRLFILNRDY 483
+ AI+ + L GL YL Y+W +R+IV G+L WI Y + +F LN +
Sbjct: 421 I---AIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGY---VICFVFSLNIEP 474
Query: 484 NSH----KSLLNYFIFGSLTIILNYVLYYQKAPFNYYMYLFFPLIFWSEIFTDRVVLDDG 539
+S S++ F +++ Y Q +P YY Y FP IF I + G
Sbjct: 475 SSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLG 534
Query: 540 VKEFL------KGISIPKRIILVSAIILVYESIVYAFFDRWIFSLIFNMLSFYP-LICGY 592
K FL G S+ K + + I+ + + IVY++F R FS+I L+ +P L+
Sbjct: 535 FKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHAD 594
Query: 593 RDWKRNTL---WFITGAAISVFTLLDAVKIESLTQINIASGLIVLTALSGFLHLRKQLNS 649
+ T+ W + + + FT+L K ESL I + + + L+ R Q
Sbjct: 595 YAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQ 654
Query: 650 YTTTV----FICQILLVILMVLATNKSIVSLQNRTGLPRDAQVAGWVILVVSLLLMPLIH 705
Y++TV + Q+L+++ V T K SLQ +P ++ + + + S ++ P H
Sbjct: 655 YSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYII-PSHH 713
Query: 706 YMKPNNNYKVRMLIIFLTFAPTFIILTISFESFFYLVFSAYIVQWIEIESKLKEQT---- 761
+ + R+ I+FLTF+PT +L+ISFE+ FY+V + W+E+E++L++ T
Sbjct: 714 IRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLH 773
Query: 762 PNTSHYKQL--------IRVTIIGFFLLQNAFFGTGNVASISSFSLDSVYRLMPIFDPFP 813
P S K IR+++ + + AFFGTGNVAS+S+F+LDSV R +P+F+P
Sbjct: 774 PEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVT 833
Query: 814 MGALLVIKLIIPYIILSAGLGILNLKLHIKDYXXXXXXXXXXXXXXXNFFYLLKTEGSWL 873
GALL+ +++P+I LSA GI+N +L NFFYL+K EGSW
Sbjct: 834 QGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWK 893
Query: 874 DIGITISNYCLAILSSLFMLILEIVAHVVLKNV 906
DIG++IS++C++ LF+ LE + ++ KN+
Sbjct: 894 DIGVSISHFCISNFLILFITALEHASAILCKNI 926
>Hs6912500 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 931
Score = 557 bits (1435), Expect = e-158
Identities = 336/938 (35%), Positives = 528/938 (55%), Gaps = 66/938 (7%)
Query: 7 LYFIVAGVLFHLFYLWSIFDIYFVSPLVHGMKQHQSTDEAPAKRLFLIVGDGLRADTTFD 66
L F G+L H + SIFDIYF SPLVHGM + PA+RL L V DGLRAD
Sbjct: 2 LLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADA--- 58
Query: 67 KILHPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
L+ + + AP+IR+++ +E ++G+SHTR+PTESRPGHVA+IAGFYEDVSAV KGW
Sbjct: 59 --LYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116
Query: 127 QENPVDFDSFFNQSKHTYSFGSPDILPMFKDGATPNKVDAWMYGHEFEDF-TQSSIELDA 185
+ENPV+FDS FN+SK+T+S+GSPDILPMF GA+ + V + Y + EDF Q + +LD
Sbjct: 117 KENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDT 176
Query: 186 FVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDK 245
+VF ++ + F++ ++N++L ++I ++ VFFLHLLG DT GH++RP S +Y N+K +D
Sbjct: 177 WVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDD 236
Query: 246 EVKLLVEKVHEFF-DDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGINKPVKN 304
VK +V + F+ +D T FIFT+DHGM+ +GSHG GHP+ T TPLV WGAGI P +
Sbjct: 237 GVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRV 296
Query: 305 QAPIFDN-YTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGELPLNFIDAPEDKK 363
A FD+ + + W L + KR DVNQADIA LM+ LIG +P+NSVG LP+++++ + K
Sbjct: 297 SAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFK 356
Query: 364 LNALFNNAKAILEQYLVK--EQEIIASQFVYKEYEAFVEIPYQEYLQQIESLIERIAKGE 421
++F NA ILEQ+ VK +++ + F++ ++ + L++ S I +
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYI------K 410
Query: 422 NELEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIVYSFSIFLR-----L 476
+ + + L +EL+ + L GL+Y TY+ F+ V +GF+GWI Y+ + ++ +
Sbjct: 411 HRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLI 470
Query: 477 FILNRDYNSHKSLLNYFIFGSLTIILNYVLYYQKAPFNYYMYLFFPLIFWSEIFTDRVVL 536
++++ LL F ++ I++ + L Q P+ YY+Y PL W + + V+
Sbjct: 471 KGVSKEVKKPSHLLP-CSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVI 529
Query: 537 DDGVKEFLKGISIPKRIILVSAIILVYESIVYAFFDRWIFSLIFNMLSFYPLICGYRDWK 596
D V L + + + A L E +V +FF R++ + + +P + R W
Sbjct: 530 QDLVVSVLT-YPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLT--RLWT 586
Query: 597 RNTL----WFITGAAISVFTLLDAVKIESLTQINIASGLIV-LTALSGFLHLRKQLNSY- 650
R + W ++VF L+ V + + + +GL+V L +L L K+ +S+
Sbjct: 587 RAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFI 646
Query: 651 --TTTVFICQILLVILMVLATNKSIVSLQNRTGLPRDAQVAGWVI----LVVSLLLMPLI 704
V + Q+L +L + + SL + GLP Q+ W LVV LL P++
Sbjct: 647 KEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVL 706
Query: 705 HYMKPNNNYKVRMLIIFLTFAPTFIILTISFESFFYLVFSAYIVQWIEIESKLKEQT--- 761
R+ I L+ T+++L+ +E+ F LV S + WI IE + +Q+
Sbjct: 707 FQ---------RLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVC 757
Query: 762 -------------PNTSHYKQL----IRVTIIGFFLLQNAFFGTGNVASISSFSLDSVYR 804
+ + ++QL IR F L AFFGTGN+ASI+SF L SVY
Sbjct: 758 CKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYC 817
Query: 805 LMPIFDPFPMGALLVIKLIIPYIILSAGLGILNLKLHIKDYXXXXXXXXXXXXXXXNFFY 864
+ +F PF MGAL++ K++IP++++ + L + +FF+
Sbjct: 818 FLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFF 877
Query: 865 LLKTEGSWLDIGITISNYCLAILSSLFMLILEIVAHVV 902
L+K GSWLDIG +IS+Y + + ++F++ L +A ++
Sbjct: 878 LVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLL 915
>At3g01380 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 921
Score = 498 bits (1283), Expect = e-140
Identities = 324/952 (34%), Positives = 501/952 (52%), Gaps = 117/952 (12%)
Query: 4 RHRLYFIVAGVLFHLFYLWSIFDIYFVSPLVHGMKQHQST-DEAPAKRLFLIVGDGLRAD 62
R + +V GV H Y+ SIFDIYF +P+VHGM E PAKRL L++ DGLRAD
Sbjct: 41 RRETWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRAD 100
Query: 63 TTFDKILHPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFYEDVSAV 122
F+ E Y AP++R++++N+ +GVSH R PTESRPGHVA+IAGFYED SAV
Sbjct: 101 KFFEP-----DEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAV 155
Query: 123 TKGWQENPVDFDSFFNQSKHTYSFGSPDILPMFKDGATPNKVDAW-MYGHEFEDFTQSSI 181
TKGW+ NPV+FDS FNQS+HT++FGSPDI+P+F A P+ W Y HE+EDF +
Sbjct: 156 TKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCS-ALPHST--WNSYPHEYEDFATDAS 212
Query: 182 ELDAFVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVK 241
LD + F L N + ++ L+ + QD V FLHLLGCD+ GH++RPYS+ Y +NVK
Sbjct: 213 FLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVK 272
Query: 242 YIDKEVKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGIN-- 299
+DK + + + +++ D T++IFTADHGMS GSHGDGHP NT TPLVAWGAGI
Sbjct: 273 VVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYP 332
Query: 300 KPVKNQA------PIFDNYTE------NWNLADIKRNDVNQADIASLMSYLIGANYPVNS 347
KP + D + +W L ++R DVNQADIA LMS L+G PVNS
Sbjct: 333 KPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNS 392
Query: 348 VGELPLNFIDAPEDKKLNALFNNAKAILEQYLVKEQEIIASQFVYKEYEAFVEIPYQEYL 407
VG LPL ++ E +++ A+ N K IL Q L K ++ +K ++ V + L
Sbjct: 393 VGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLVHHSFS--L 450
Query: 408 QQIESLIERIAKGENELEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIV 467
QI+ LI AK A+KL +L ++L+GL Y TY+W + T++TLG+ GW++
Sbjct: 451 SQIDELIS--AKSYEA----AMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMI 504
Query: 468 YSFSIFLRLFILNRDYNSHKSLLNYFIFGSLTI-ILNYVLYYQKAPFNYYMYLFFPLIFW 526
L+ + S K L+ +I G L + IL+ + + +P Y+ Y+ + W
Sbjct: 505 VLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLW 564
Query: 527 SEIFTDRVVLDDGVKEFL---KGISIPKRIILVSAIILVYESIVYAFFDRWIFSLIFNML 583
++IF++ ++ G+ ++L + K + + +++ E +V++F +R +++
Sbjct: 565 TQIFSEYRLI-RGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYT------ 617
Query: 584 SFYPLICGYRDWKRNTLWFITGAAISVFTLLDAVKIESLTQINIASGLIVLTALSGFLHL 643
WF A + LL I SG+ V +S
Sbjct: 618 -----------------WFFLIAGVVASILLH-------FSIPWRSGIPVFVCIS----- 648
Query: 644 RKQLNSYTTTVFICQILLVILMVLATNKSIVSLQNRTGLPRDAQVAGWVILVVSLLLMPL 703
C L V ++ A +L + D + GW ++ +
Sbjct: 649 -------------CWFLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWCVICDGV----- 690
Query: 704 IHYMKPNNNYKVRMLIIFLTFAPTFIILTISFESFFYLVFSAYIVQWIEIE------SKL 757
++ +N + R I F+T +++ +E+ FY + ++ WI E SK+
Sbjct: 691 --FVDKASNAESR--IAFVT--SVHKLVSCRYEAVFYSALAVVLMAWILFENASHHSSKV 744
Query: 758 KEQTPNTSH------------YKQL--IRVTIIGFFLLQNAFFGTGNVASISSFSLDSVY 803
KE + + ++ Y QL +R+ ++ L AFFGTGN ASI+SF + SVY
Sbjct: 745 KESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVY 804
Query: 804 RLMPIFDPFPMGALLVIKLIIPYIILSAGLGILNLKLHIKDYXXXXXXXXXXXXXXXNFF 863
R + IF PF M ALL+ KL IP++++ + + + +FF
Sbjct: 805 RFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFF 864
Query: 864 YLLKTEGSWLDIGITISNYCLAILSSLFMLILEIVAHVVLKNVQLSKPVIAS 915
+L+K GSW++IG +IS++ + +F+L+L + ++ +++++ KP+ S
Sbjct: 865 FLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYTRSIRI-KPLSTS 915
>7303806 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 874
Score = 301 bits (772), Expect = 2e-81
Identities = 239/909 (26%), Positives = 426/909 (46%), Gaps = 76/909 (8%)
Query: 9 FIVAGVLFHLFYLWSIFDIYFVSPLVHGMKQHQSTD----EAPAKRLFLIVGDGLRADTT 64
+I ++ H+ L SIF IYF SP++ G+ + E PA RL LIV DG RAD+
Sbjct: 2 WIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSF 61
Query: 65 FDKILHPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFYEDVSAVTK 124
F+ E+ P +R + E GVS TR+PTE+RPGH+ +IAG YED SAV +
Sbjct: 62 FE--------ENCRYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLR 113
Query: 125 GWQENPVDFDSFFNQSKHTYSFGSPDILPMFKDGATPNKVDAWMYGHEFEDFTQS--SIE 182
GW+ NP+DFD+ FN+S TY++G+ D+L +F + +++ Y H+ DF+ + E
Sbjct: 114 GWKSNPIDFDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDL-DFSPGYDAYE 172
Query: 183 LDAFVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKY 242
D +VF+ + L + E + VFFLHLLG DTAGH ++P + ++ ++
Sbjct: 173 EDEWVFKRVKLLLQQKR-----EALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEK 227
Query: 243 IDKEVKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGINKPV 302
+K V + ++ F D+ TA++ TADHGM+ G+ + V G
Sbjct: 228 TEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGA----------SRAVPKPGGRTFMP 277
Query: 303 KNQAPIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGELPLNFIDAPEDK 362
N+ P + +++ QA + LMS L+G P+N+ G+LPL +++ ++
Sbjct: 278 NNEGPA------------MPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKEY 325
Query: 363 KLNALFNNAKAILEQYLVKEQEIIASQF--VYKEYEAFVEIPYQEYLQQIESLIERIAKG 420
+ A NA +LEQY+ +++ F + EY+ + Y +++++ K
Sbjct: 326 EAMAAHVNALQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYK---DTIVQLQKKR 382
Query: 421 ENELEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIVYSFSIFLRLFILN 480
E L I ++ +M L+G+ Y Y R + T FLGW+ Y + + R
Sbjct: 383 EYSL---CIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASK 439
Query: 481 RDYNSHKS--LLNYFIFGSLTIILNYVLYYQKAPFNYYMYLFFPLIFWSEIFTD-RVVLD 537
+ +S ++ I S+ I+L L Q P + YL P W + +
Sbjct: 440 VELVLERSNKIVRVSIVSSV-IVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWNINFS 498
Query: 538 DGVKEFLKGISIPKRIILVSAIILVYESIVYAFFDRWIFSLIFNMLSFYPLICGYRDWKR 597
++ + + +I E +V+ FF+R + +L F + + Y ++ WK
Sbjct: 499 SSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFACYNSWENFQ-WKS 557
Query: 598 NTL--WFITGAAISVFTLLDAVKIESLTQINIASGLIVLTALSGFLHLRKQLNSYTTTVF 655
W +S F LL + + + +G+IV+ S F + + +L T +
Sbjct: 558 RDFFSWLALVLILSCFPLLP-LSVGYQNGYLLGAGVIVIFTNS-FWNSKSRLCYRNHTKY 615
Query: 656 ICQILLVILMVLATNKSIVSLQNRTGLPRDAQVAGWVILVVSLLLMPLIHYMKPNNNYKV 715
++L+ ++ A S N +P ++A W+ LV + + L + +
Sbjct: 616 SNALILLQTILCAYLHS-----NGINIPIPLKLASWLYLVYAFASILL----SKESRLDL 666
Query: 716 RMLIIFLTFAPTFIILTISFESFFYLVFSAYIVQWIEIESKLKEQTPNTSHYKQLIRVTI 775
R+ I + L S+E+ F VQ + IE + + + + ++R+
Sbjct: 667 RLAQIGFNLGSLYATLCTSYEAVF--------VQLLTIELNISLRAQSARAERSVLRLAF 718
Query: 776 IGFFLLQNAFFGTGNVASISSFSLDSVYRLMPIFDPFPMGALLVIKLIIPYIILSAGLGI 835
+ FG+GN+ASISSF + + F PF + L+++KL++P +++ + +
Sbjct: 719 TLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVVLIMSVIYA 778
Query: 836 LNLKLHIKDYXXXXXXXXXXXXXXXNFFYLLKTEGSWLDIGITISNYCLAILSSLFMLIL 895
+ + + NF +L++ +GSWLDIG +IS++ + +++L ML++
Sbjct: 779 NSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEVTTLVMLVI 838
Query: 896 EIVAHVVLK 904
A +L+
Sbjct: 839 FYTAKQLLR 847
>CE25439 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 348
Score = 280 bits (715), Expect = 9e-75
Identities = 149/353 (42%), Positives = 221/353 (62%), Gaps = 34/353 (9%)
Query: 9 FIVAGVLFHLFYLWSIFDIYFVSPLVHGMK-QHQSTDEAPAKRLFLIVGDGLRADTTFDK 67
F++A + HL ++SIFD+Y+ SPLVHG+ Q ++ EAPAKR+F+I DGLR DT F+K
Sbjct: 5 FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT-FNK 63
Query: 68 ILHPVTGEHDYLAPYIRDLVRN-EATYGVSHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
+ +PY+ ++ + YG+S + +PTESRPGHVA+ AG ED+SAV KGW
Sbjct: 64 --------YPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGW 115
Query: 127 QENPVDFDSFFNQSKHTYSFGSPDILPMFKDGATPNKVDAWMYGHEFEDF-TQSSIELDA 185
++NPV FDS FN+S +++ +GSPDI+ +F D PN +++ Y + EDF ++ + LD
Sbjct: 116 KKNPVQFDSVFNRSSYSWMWGSPDIVNLFDD--LPN-AESFSYSADEEDFASKDASNLDK 172
Query: 186 FVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDK 245
+VF H K+++ L ++++ ++FFLHLLG DT GH +P S +Y DN+K +D
Sbjct: 173 WVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDS 232
Query: 246 EVKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGINKPVKNQ 305
++ + V FF D TA++FT+DHGM+ +GSHG G + TP VAWGAG VK
Sbjct: 233 GIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAG----VKQG 288
Query: 306 APIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGELPLNFIDA 358
P + D+NQ D+A L+S LIG PVNS+G LP+ +++
Sbjct: 289 GP---------------KLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNS 326
>7300908 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 919
Score = 196 bits (497), Expect = 2e-49
Identities = 236/975 (24%), Positives = 397/975 (40%), Gaps = 141/975 (14%)
Query: 1 MWSRHRLYFIVAGVLFHLFYLWSIFDIYFVSPLVHGMKQHQSTDEA----PAKRLFLIVG 56
MWS + ++ HL L SI IYF S ++ ++ + E PA RL + V
Sbjct: 1 MWS-------IQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVV 53
Query: 57 DGLRADTTFDKILHPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFY 116
DGLRA + V +H P +R+L +A G+S PT +RPGH+A+ GF
Sbjct: 54 DGLRAQS--------VLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFN 105
Query: 117 EDVSAVTKGWQENPVDFDSFFNQSKHTYSFGSPDILPMFKD---GATPNKVDAWMYGHEF 173
ED +A T W NP FDS FN+S++ + ++ +F G P + F
Sbjct: 106 EDPAA-TLTW--NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLR---------F 153
Query: 174 EDFTQSSIE----LDAFVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSY 229
E F +S I LD + F + N ++ + L +FF++L D A H +
Sbjct: 154 ETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSV---IFFVYLADIDLAEHVH 210
Query: 230 RPYSAEYYDNVKYIDKEVKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRT 289
P S + + + Y + ++ E F+D TA++ TAD+G+S HG G T
Sbjct: 211 MPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGISL---HGGGGERGVET 267
Query: 290 PLVAWGAGINKPVKNQAPIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVG 349
P + WGAG+ + N N+T N + + Q +A LMS LIG P+N++
Sbjct: 268 PFILWGAGVKRSAPNPG---QNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMA 324
Query: 350 ELPLNFIDAPEDKKLNALFNNAKAILEQ--YLVKEQEIIASQFVYKEYEAFVEIPYQEYL 407
+PL F++ +L L NA +L Q L+K E + ++E+ + Y
Sbjct: 325 LMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYP 384
Query: 408 QQIESLIERIAKGENELEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIV 467
Q I+ L+ + E +A+K++ ++ K+ + + Y Y + T +L W
Sbjct: 385 QIIKYLVAK------EQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVW-- 436
Query: 468 YSFSIFLRLFILNRDYNSHKS-LLNYFIFGSLT-----IILNYVLYYQKAPFNYYMYLFF 521
+L L L R+ N KS Y + +L ++L ++ Q+ P YL
Sbjct: 437 ----FYLLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLL 492
Query: 522 PLIFWSEIFTDRVVLD-DGVKEF----LKGISIPKRIILVSA-----IILVYESIV---- 567
P +R D D + +F L GI +P ++++ A I L+Y IV
Sbjct: 493 PFGILILALAERPCQDRDLMCQFPVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNN 552
Query: 568 -YAFFDRWIFSLIFNMLSFYPLICGYRDWKRN-TLWFITGAAISVFTLLDAVKIESLTQI 625
AFF R LIF L+ L+ G K++ +L FIT I
Sbjct: 553 RRAFF-RPSLKLIF-WLALVFLLSGILLVKQSASLHFITDT------------------I 592
Query: 626 NIASGLIVLTALSGFLHLRKQL---NSYTTTVFICQILLVILMVLATNKSIVSLQNRTGL 682
+ G + S L + + L + ++T V+I + +L T I +
Sbjct: 593 GVYIGNSHVVYFSMILSIIRPLILGHQHSTRVWIVN----MAALLVTAYGIYQWDADQPV 648
Query: 683 PRDAQVAGWVILVVSLLLMPLIHYMKPNNNYKVRMLIIFLTFAPTFIILTISFESFFYLV 742
A W L+ + L +P + + R+ +I I+LT S S F +
Sbjct: 649 CTYVYAACWSYLLFAFLSIP----YSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQI 704
Query: 743 FSAYIVQWIEIE-----------------------SKLKEQTPNT--SHYKQLIRVTIIG 777
V +E+ + + ++PN H +Q R +
Sbjct: 705 MVTEFVLGLELYEESFSYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALI 764
Query: 778 FFLLQNAFFGTGNVASISSFSLDSVYRLMPIFDPFPMGALLVIKLIIPYIILSAGLGILN 837
L +FFGTG+ +F + P F + A +++K+ IP II+ + + L
Sbjct: 765 LLYLYISFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYAL- 823
Query: 838 LKLHIKDYXXXXXXXXXXXXXXXNFF-YLLKTEGSWLDIGITISNYCLAILSSLFMLILE 896
+ K+ +F Y + GS + ++ ++ + + +L+
Sbjct: 824 VSFGRKNVRSIFICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCS 883
Query: 897 IVAHVVLKNVQLSKP 911
+A L N + KP
Sbjct: 884 WIAKGFLANTKKDKP 898
>7301592 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 475
Score = 133 bits (335), Expect = 1e-30
Identities = 123/523 (23%), Positives = 219/523 (41%), Gaps = 91/523 (17%)
Query: 14 VLFHLFYLWSIFDIYFVSPLVHGMKQHQSTDEA----PAKRLFLIVGDGLRADTTFDKIL 69
++ H+ + +I + YF L+ + ++ E PA RL + V DGLRA T
Sbjct: 7 LVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAATFL---- 62
Query: 70 HPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFYEDVSAVTKGWQEN 129
+ P ++D+ R + G+S T PT +RPGH+A+ AGF+ED +A N
Sbjct: 63 ----ANNGSDVPDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAASLMHLCYN 118
Query: 130 PVDFDSFFNQSKHTYSFGSPDILPMF---KDGATPNKVDAWMYGHEFEDFTQSSIELDAF 186
P DFD+ FN+S++ + I+ F G P + D++M E + D +
Sbjct: 119 PGDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYM-----ERDLPEKLTCDKW 173
Query: 187 VFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDKE 246
F + N + + VFF++L D A H ++P A
Sbjct: 174 AFDKVENFLRNVDNVREWR---NYKPAVFFVYLADMDIAAHRFKPLRA------------ 218
Query: 247 VKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGINKPVKNQA 306
HG G P TPL WGAG+ +++
Sbjct: 219 --------------------------------HGSGSPLEVETPLFMWGAGVK---RDEI 243
Query: 307 PIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGELPLNFIDAPEDKKLNA 366
N+ E N+ + V+Q +A LMS LIG P N++ +P+ +++ ++ + A
Sbjct: 244 DAEANFPEKPNI-----SQVDQTQLAPLMSSLIGLPPPKNNLALMPVGYLNVSDEYQAVA 298
Query: 367 LFNNAKAILEQ---YLVKEQEIIASQFVYKEYEAFVEIPYQEYLQQIESLIERIAKGENE 423
L N +L Q + + ++ I +++ K E + + +Y Q + I K E
Sbjct: 299 LHLNVLQLLSQAEILIGRHEKAIFYKWLPKFKELHIGV-IDQYAAQFD-----ILKSEGN 352
Query: 424 LEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIVYSFSIFLRLFILNRDY 483
L DA++ +E K+ L Y YN + ++ + ++++ + + L+L L++
Sbjct: 353 L-TDAMEFCKEYGKLAKKCLTY---YNQYYQTPLIVANSMSYMIWFYCLLLQLTRLSKKE 408
Query: 484 NSHK---SLLNYFIFGSLTIILNYVLYYQKAPFNYYMYLFFPL 523
+ ++ I + I+L ++ QK P YL P+
Sbjct: 409 KMQRRGFMTVSTLILAMIGILLIAMMELQKVPHIAAFYLILPV 451
>7299469 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 858
Score = 124 bits (311), Expect = 7e-28
Identities = 200/866 (23%), Positives = 340/866 (39%), Gaps = 154/866 (17%)
Query: 14 VLFHLFYLWSIFDIYFVS-PLVHGMKQHQSTDEA---PAKRLFLIVGDGLRADTTFDKIL 69
VL HL L I I++ S PL Q D A RL + + +GLRADT F
Sbjct: 9 VLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADTLFS--- 65
Query: 70 HPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAGFYEDVSAVTKGWQEN 129
++ A YIRD++ + G+S T +PT +R VA+ AGF N
Sbjct: 66 -----DNCSGAVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGF-------------N 107
Query: 130 PVDFDSFFNQSKHTYSFGSPDILPMFKDGATPNKVDAWMYGHEFEDFTQSSIELDAFV-F 188
P+ P ILP N+ A+ G AF+ F
Sbjct: 108 PM-----------------PSILPTSNFDTIFNRTLAFDKG--------------AFLRF 136
Query: 189 RHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDKEVK 248
H+ +L LE + V ++L + G S P + + + ++
Sbjct: 137 SHLSDLRRRLTKRACLEKLWYANKLVMLVNL--AEVGGAS--PLDIGFQMKLHNTQRNIR 192
Query: 249 LLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGINKPVKNQAPI 308
E + F+D TA+++T+ HG++ FGSHG G P + WGAG+ +N I
Sbjct: 193 DAYELIEATFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTEN---I 249
Query: 309 FDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGELPLNFID-----APEDKK 363
++ N N ++ + ++Q +A LMS LIG PVN++ LP ++ A +
Sbjct: 250 TSDFVLN-NGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVH 308
Query: 364 LNA--LFNNAKAIL--------EQYLVKEQEIIASQFVYKEYEAFVEIPYQEYLQQIESL 413
LNA L AKAI+ ++L K++++ Q Y Y Q++ L
Sbjct: 309 LNALQLLTQAKAIIRLHERGVFHKWLPKDKDLDLQQIAY-------------YQNQMDHL 355
Query: 414 IERIAKGENELEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVT--LGFLGWIVYSFS 471
++ + + A++ + +KV L L + +N+ I +VT L LGW Y
Sbjct: 356 LDMGWRSK------ALETSTLAIKVALKSLKFY--HNYYHIPLVVTTVLALLGWQFYQL- 406
Query: 472 IFLRLFILNRDYNSHKSLLNYFIF-GSLTIILNYVLYYQKAPFNYYMYLFFPLIFWSEIF 530
+ L ++ Y L IF SL ++L +++ Q APF + L P W
Sbjct: 407 VKLSQNVMAPHYMRRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVW--CM 464
Query: 531 TDRVVLDDGVKEF-----LKGISIPKRIILVSAIILVYESIVY----AFFDR--WIF--S 577
T + +G F L+ I P +++ S S+ Y F++R W+
Sbjct: 465 TLAALPQNGGWIFEPLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRGWLHPSP 524
Query: 578 LIFNMLSFYPLICGYRDWKRNTLWFITGAAISVFTLLDAVKIESLTQINIASGLIVLTAL 637
L+ L+ G+ LW G I + T V +++++ + + VL
Sbjct: 525 KFLAWLALVLLLGGF-------LWSQKGMQI-LMTTNYRVVLQAISMLVVIVRPCVL--- 573
Query: 638 SGFLHLRKQLNSYTTTVFICQILLVILMVLATNKSIVSLQNRTGLPRDAQVAGWVILVVS 697
+ + + V IL V + I + +P A W L+ +
Sbjct: 574 -------NENHKWKVWVINGGILFVAAI------GIFLKEMGKPVPLYLFAANWAYLIYA 620
Query: 698 LLLMPLIHYMKPNNNYKVRMLIIFLTFAPTFIILTISFESFFYLVFSAYIVQWIEIESKL 757
+P P + R+ +I ++L+ S+ S F +E+ K
Sbjct: 621 FASVPCSSRTTPQS----RLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKF 676
Query: 758 KEQ------TPNTSHYKQLIRVTIIGFFLLQNAFFGTGNVASISSFSLDSVYRLMPIFDP 811
KE ++ H + R + + FGTG+ ++ +S +P
Sbjct: 677 KEADEDVKILTSSKHLQMCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSS 736
Query: 812 FPMGALLVIKLIIPYIILSAGLGILN 837
+ L++I L+IP I++ A + L+
Sbjct: 737 GLVPLLVLIHLLIPSIVIMASVVALS 762
>CE18060 [T] KOG2124 Glycosylphosphatidylinositol anchor synthesis protein
Length = 559
Score = 100 bits (249), Expect = 1e-20
Identities = 121/544 (22%), Positives = 219/544 (40%), Gaps = 66/544 (12%)
Query: 410 IESLIERIAK-GENELEPDAIKLTEELMKVTLDGLAYLTTYNWRFIRTIVTLGFLGWIVY 468
+ESL +A+ G + A L + + + + + Y+ + + V+ F+ WI
Sbjct: 1 MESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL 60
Query: 469 SFSIFLRLFILNRDYNSHKSLL--NYFIFGSLTIILNYVLYYQKAPFNYYMYLFFPLIFW 526
S F+ N + SLL ++ L L + Y + +Y+ P I+
Sbjct: 61 VVS-----FLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLS-MTQTIYIILP-IYL 113
Query: 527 SEIFTDRVVLDDGVKEFLKGISIP----KRIILVSAIILVYESIV----------YAFFD 572
I + L ++E +K +S +++ V + + V F D
Sbjct: 114 ISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMD 173
Query: 573 RWIFSLIFNMLSFYPLICGY---RDWKRNTLWFITGAAISVFTLLDAVKIESLTQINIAS 629
R + +F +L P + W + W + +F L AV + + + I S
Sbjct: 174 RAFLAAVFVLLMALPQFYSHPIVSYWSKT--WLTLCLVLCIFPFLPAVGVSTHIPLCILS 231
Query: 630 GLIV------------LTALSGFLHLRKQLNSYTTTVFIC------QILLVILMVLATNK 671
+I LT + L L + S T + ++ +I K
Sbjct: 232 PIITAFLCHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKK 291
Query: 672 SIVSLQNRTGLPRDAQVAGWVILVVSLLLMPLIHYMKPNNNYKVRMLIIF-LTFAPTFII 730
S P A+ W + +S++ L+ Y V LI + L F + +
Sbjct: 292 SNSKSSQSLQPPSIARWISWTSIPLSVIAPSLL-----TGPYLVDRLIAYALCFYVPYSL 346
Query: 731 LTISFESFFYLVFSAYIVQWIEIES-----------KLKEQTPNTSHYKQLIRVTIIGFF 779
L+IS+ES F L+F + ++ E K+ +T Y +L R + F
Sbjct: 347 LSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSF 406
Query: 780 LLQNAFFGTGNVASISSFSLDSVYRLMPIFDPFPMGALLVIKLIIPYIILSAGLGILNLK 839
+L FGTGN ASI+SF+ ++ + +F PF M LL++KL+IP +++++ +
Sbjct: 407 VLC-PLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRF 465
Query: 840 LHIKDYXXXXXXXXXXXXXXXNFFYLLKTEGSWLDIGITISNYCLAILSSL-FMLILEIV 898
FF+ L+ EGSWLDIG++IS + +++ SL +L+L I
Sbjct: 466 DQESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSIS 525
Query: 899 AHVV 902
+H++
Sbjct: 526 SHLM 529
>YJL062w [T] KOG2125 Glycosylphosphatidylinositol anchor synthesis protein
Length = 830
Score = 74.3 bits (181), Expect = 8e-13
Identities = 95/372 (25%), Positives = 150/372 (39%), Gaps = 51/372 (13%)
Query: 12 AGVLFHLFYLWSIFDIYFVSPLVHGMKQHQSTD---EAPAKRLFLIVGDGLRADTTFDKI 68
A +L L ++++ F V + Q D + P ++L ++ D LR+D FD
Sbjct: 12 AQLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSDFLFDSQ 71
Query: 69 LHPVTGEHDYLAPYIRDLVRNEATYGVSHTRMPTESRPGHVAMIAG----FYEDVSAVTK 124
+ H +L EA S PT + P ++ G F + + V +
Sbjct: 72 ISHFNNVHQWLNT-------GEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQ 124
Query: 125 GWQENPV-DFDSF---FNQSKHTYSFGSPDI-LPMFKDGATPNKVDAWMYGHEFEDFTQS 179
N + + DS+ F Q +T F D L +F W +F D T S
Sbjct: 125 DIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQ--------QWF---DFADPTHS 173
Query: 180 SIELDAFVFRHIYELFNNTKSNKTLETEIKQDG---NVFFLHLLGCDTAGHSYRPYSAEY 236
F ++ NN N L ++ Q+ +V LH LG D GH P+S
Sbjct: 174 ------FFVSDFTQVDNNVTRN--LPGKLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFM 225
Query: 237 YDNVKYIDKEVKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTR------TP 290
+ +D +K + ++V E DD+DT DHGM+ G+HG T +P
Sbjct: 226 AAKHQEMDSILKSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSP 285
Query: 291 LVAWGAGINKPVKNQAPIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGE 350
+A A V PI N + +WN ++ V Q DI ++ L G P+NSVG
Sbjct: 286 KLAQFARPESQVNYTLPI--NASPDWNFQYLE--TVQQIDIVPTIAALFGMPIPMNSVGI 341
Query: 351 LPLNFIDAPEDK 362
+ +F+ +K
Sbjct: 342 IIPDFLQLLPNK 353
>CE03275 [T] KOG2125 Glycosylphosphatidylinositol anchor synthesis protein
Length = 795
Score = 69.3 bits (168), Expect = 3e-11
Identities = 50/206 (24%), Positives = 89/206 (42%), Gaps = 27/206 (13%)
Query: 176 FTQSSIELDAFVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLLGCDTAGHSYRPYSAE 235
F ++D V RH+ +NT + + LH LG D GHS S++
Sbjct: 219 FVSDYTDVDNNVTRHLDTELSNTNHS----------WDALILHYLGLDHIGHSLGGSSSK 268
Query: 236 YYDNVKYIDKEVKLLVEKVHEFFD-----DEDTAFIFTADHGMSAFGSHGDGHPNNTRTP 290
+ +K +D ++ ++H++ D+++ I DHGM+A GSHG P+ TR P
Sbjct: 269 IPEKLKEMDD----VIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVP 324
Query: 291 LVAWGAGINKPVKNQAPIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGE 350
+V W G + KN D+ + + Q D++S + + P+ S G
Sbjct: 325 VVIWKFGREEGNKNYGNQDDSLKQ--------PPRIEQIDVSSTIFDVFNMPIPIESYGI 376
Query: 351 LPLNFIDAPEDKKLNALFNNAKAILE 376
+N+ E++ N + I++
Sbjct: 377 SLINYFSDDEEEYFEKQHNQFRRIVQ 402
>7304201 [T] KOG2125 Glycosylphosphatidylinositol anchor synthesis protein
Length = 880
Score = 68.9 bits (167), Expect = 3e-11
Identities = 75/272 (27%), Positives = 113/272 (40%), Gaps = 33/272 (12%)
Query: 175 DFTQSSIELDAFVFRHIYELFNNTKSNKTLETEIKQ-DGNVFFLHLLGCDTAGHSYRPYS 233
+FT+ D+F YE N KTLETE+++ D ++ LH LG D GH S
Sbjct: 163 EFTRQVENHDSFYVNDFYEGDRNV--TKTLETELERSDWSLLILHYLGLDHIGHVEGNAS 220
Query: 234 AEYYDNVKYIDKEVKLLVEKVHEFFDDEDTAFIFTADHGMSAFGSHGDGHPNNTRTPLVA 293
+K +D+ VK +++ H+ F + + T DHGM+ G HG P T PL
Sbjct: 221 PRVPLKLKEMDEVVKKILD--HKSFPN--VLLMLTGDHGMADGGGHGGNTPAETLVPLYL 276
Query: 294 WGAGINKPVKNQAPIFDNYTENWNLADIKRNDVNQADIASLMSYLIGANYPVNSVGEL-P 352
Y N + NQ D+A +S L+ P S+G L P
Sbjct: 277 ------------------YYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIP 318
Query: 353 LNFIDAPEDKKLNALFNNAKAILEQYLVK-EQEIIASQFVYKEYEAFVEIPYQEYLQQIE 411
+ +L A F NA +L + VK EI+ Y Y+ + + + +
Sbjct: 319 EMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLL----HKKLLR 374
Query: 412 SLIERIAKGENELEPDAIKLTEELMKVTLDGL 443
L E G +++ KL M++ LDGL
Sbjct: 375 PLREGDGGGASQVYYQNAKL--NYMRLQLDGL 404
>At2g22530 [T] KOG2125 Glycosylphosphatidylinositol anchor synthesis protein
Length = 897
Score = 60.5 bits (145), Expect = 1e-08
Identities = 95/409 (23%), Positives = 152/409 (36%), Gaps = 77/409 (18%)
Query: 9 FIVAGVLFHLFYLWS-IFDIYFVSPLVHGMKQHQSTDEA---------------PAK-RL 51
F VAG+L + L +F + V P + G+ +S + P K RL
Sbjct: 14 FTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRL 73
Query: 52 FLIVGDGLRADTTFDKILHPVTGEHDYLAPYIRDLVRNEATYGV-SHTRMPTESRPGHVA 110
V DGL A+ K P PY + L+ N G + PT + P A
Sbjct: 74 LYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKA 133
Query: 111 MIAGFYEDVSAVTKGWQENPVDFDS----FFNQSKHTYSFGSPDILPMFK------DGAT 160
M++G V + + D+ FF G L +F DG +
Sbjct: 134 MVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGVS 193
Query: 161 PNKVDAWMYGHEFEDFTQSSIELDAFVFRHIYELFNNTKSNKTLETEIKQDGNVFFLHLL 220
F + ++++D V RH+ + N+ D N+ LH L
Sbjct: 194 -------------SFFVKDTVQVDRNVSRHLPDELNS------------DDWNLLILHYL 228
Query: 221 GCDTAGHSYRPYSAEYYDNVKYIDKEVKLL-----VEKVHEFFDDEDTAFIFTADHGMSA 275
G D GH+ S +K +D V+ + +++ H D T I +DHGM+
Sbjct: 229 GLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSH---DQGQTLLIIVSDHGMTE 285
Query: 276 FGSHGDGHPNNTRTPLVAWGAGINKPVKNQAPIFDNYTENWNLADIKRNDVNQADIASLM 335
G+HG T + ++ G+N + + A +N Q D+A +
Sbjct: 286 NGNHGGSSYEETDSLMLF--IGLNSNISDYASATNNV-------------AFQVDLAPTL 330
Query: 336 SYLIGANYPVNSVGEL-PLNFIDAPEDKKLNALFNNAKAILEQYLVKEQ 383
+ L G P N+VG L P + ++L AL N+ +L L + Q
Sbjct: 331 ALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQ 379
>SPAC13G6.03 [T] KOG2125 Glycosylphosphatidylinositol anchor synthesis protein
Length = 758
Score = 56.2 bits (134), Expect = 2e-07
Identities = 73/330 (22%), Positives = 124/330 (37%), Gaps = 53/330 (16%)
Query: 40 HQSTDEAPAKRLFLIVGDGLRADTTFDKILHPVTGEHDYLAPYIRDLVRNEATYGVSHT- 98
+Q + A ++ ++ D LRAD F K + P+ + L+ N +T+G+ +
Sbjct: 37 NQFSPPAVIDQVVFVMVDALRADFVFSK---------SHNMPFTQSLLYN-STHGIGFSA 86
Query: 99 --RMPTESRPGHVAMIAGFYEDVSAVTKGWQENPVDFDSFFNQSKHTYSFGSPDILPMFK 156
R PT + P A+ G V E+ S Q Y S F
Sbjct: 87 FARSPTVTMPRLKALTTGTIPGFLDVLLNIAESDTG-SSIEAQDSWVYQLNS------FN 139
Query: 157 DGATPNKVDAWM--YGHEFEDFTQSSIELDAFVFRHIYELFNNTKSN--KTLETEIKQDG 212
D W+ + F F ++ +F E+ NN N L + +
Sbjct: 140 KKIEFYGDDTWLKLFPSAFSKFEGTT----SFFVSDYTEVDNNVTRNFDHALPSSLSHSW 195
Query: 213 NVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDKEVKLLVEKVHEFFDDED------TAFI 266
+ LH LG D GH Y P S N+K + E+ ++ +++++ + D + +
Sbjct: 196 DALILHYLGVDHIGHLYGPSSPLL--NIKLL--EIDTIISRIYKYLQEYDEKTNTHSLIV 251
Query: 267 FTADHGMSAFGSHGDGHPNNTRTPLVAWG-----AGINKPVKNQAPIFDNYTENWNLADI 321
DHGM+ G+HG T L + INKP+ N + E
Sbjct: 252 LCGDHGMNEVGNHGGSSSGETTAALSLLFPSNELSHINKPILNMDDNPYSILER------ 305
Query: 322 KRNDVNQADIASLMSYLIGANYPVNSVGEL 351
V Q D+ + L+G P ++G++
Sbjct: 306 ----VEQVDVVPTICLLLGIPIPKGNMGKV 331
>YLL031c [T] KOG2126 Glycosylphosphatidylinositol anchor synthesis protein
Length = 1017
Score = 55.8 bits (133), Expect = 3e-07
Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 16/171 (9%)
Query: 210 QDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDKEVKLLVEKVHEFFDDEDTAFIFTA 269
++ +V H+LG D GH Y P + +D+ + +++ + D+DT +
Sbjct: 235 KEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILKSI-----DDDTLLVILG 289
Query: 270 DHGMSAFGSHGDGHPNNTRTPLVAWGAGINKPVKNQAPIFDNYTENWNLADIKRN--DVN 327
DHGM G+HG + + L + KP + T N+N+ ++ + V
Sbjct: 290 DHGMDHTGNHGGDSIDELESTLFLYS---KKPDMWRL----KETSNYNIDNLGHDYRSVR 342
Query: 328 QADIASLMSYLIGANYPVNSVGELPLNFIDAPEDKKLNALFNNAKAILEQY 378
Q D+ S ++ L+G P N++G P++ I A D++ + N+A + L+ Y
Sbjct: 343 QIDLVSSLALLMGQPIPFNNLG-WPIDEI-ARNDREWSQFVNSAISQLQLY 391
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.142 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,402,740
Number of Sequences: 60738
Number of extensions: 2327269
Number of successful extensions: 7587
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 7497
Number of HSP's gapped (non-prelim): 27
length of query: 919
length of database: 30,389,216
effective HSP length: 116
effective length of query: 803
effective length of database: 23,343,608
effective search space: 18744917224
effective search space used: 18744917224
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)