ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1863 check: MH D KOG0601 Cell cycle control, cell division, chromosome partitioning Cyclin-dependent kinase WEE1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1863 659591 661756 722
(722 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL187c [D] KOG0601 Cyclin-dependent kinase WEE1 536 e-152
SPCC18B5.03 [D] KOG0601 Cyclin-dependent kinase WEE1 278 2e-74
SPBC660.14 [D] KOG0601 Cyclin-dependent kinase WEE1 184 3e-46
7295431 [D] KOG0601 Cyclin-dependent kinase WEE1 129 2e-29
CE14884_1 [D] KOG0601 Cyclin-dependent kinase WEE1 120 1e-26
HsM4758928 [D] KOG0601 Cyclin-dependent kinase WEE1 116 1e-25
Hs21361083 [D] KOG0601 Cyclin-dependent kinase WEE1 116 1e-25
At3g20860 [R] KOG0589 Serine/threonine protein kinase 112 3e-24
ECU08g1620 [D] KOG0601 Cyclin-dependent kinase WEE1 106 1e-22
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 105 2e-22
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 103 1e-21
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 98 5e-20
YHR102w [T] KOG0201 Serine/threonine protein kinase 97 7e-20
Hs4507917 [D] KOG0601 Cyclin-dependent kinase WEE1 95 3e-19
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 95 4e-19
At3g44200 [R] KOG0589 Serine/threonine protein kinase 93 1e-18
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 93 2e-18
7299057 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 92 4e-18
HsM4506099 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 91 5e-18
Hs21618351 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 91 5e-18
Hs21618349 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 91 5e-18
Hs21618347 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 91 5e-18
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 91 5e-18
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 91 6e-18
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 91 6e-18
Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (... 91 6e-18
CE28674 [T] KOG0201 Serine/threonine protein kinase 91 6e-18
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 91 8e-18
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 91 8e-18
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 91 8e-18
At5g28290 [R] KOG0589 Serine/threonine protein kinase 90 1e-17
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 89 2e-17
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 89 2e-17
CE16527 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 89 2e-17
CE09940 [D] KOG0601 Cyclin-dependent kinase WEE1 89 3e-17
At3g04810 [R] KOG0589 Serine/threonine protein kinase 88 4e-17
Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) ki... 88 5e-17
CE07510 [T] KOG0201 Serine/threonine protein kinase 88 5e-17
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 87 9e-17
At1g54510 [R] KOG0589 Serine/threonine protein kinase 87 9e-17
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 87 1e-16
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 87 1e-16
Hs14589902 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 87 1e-16
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 87 1e-16
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 87 1e-16
Hs14589900 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 86 2e-16
At1g02970 [D] KOG0601 Cyclin-dependent kinase WEE1 86 2e-16
7295638 [T] KOG0603 Ribosomal protein S6 kinase 86 2e-16
CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 86 2e-16
CE02604 [T] KOG0695 Serine/threonine protein kinase 86 2e-16
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 86 3e-16
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 86 3e-16
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 86 3e-16
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 86 3e-16
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 86 3e-16
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 86 3e-16
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 85 3e-16
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 85 3e-16
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 85 3e-16
At1g66910 [T] KOG1187 Serine/threonine protein kinase 85 4e-16
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 84 6e-16
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 84 6e-16
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 84 6e-16
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 84 6e-16
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 84 6e-16
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 84 6e-16
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 84 6e-16
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 84 8e-16
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 84 8e-16
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 84 8e-16
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 84 1e-15
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 84 1e-15
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 84 1e-15
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 84 1e-15
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 84 1e-15
At1g66980_2 [T] KOG1187 Serine/threonine protein kinase 84 1e-15
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 83 1e-15
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 83 1e-15
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 83 1e-15
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 83 1e-15
At1g66920 [T] KOG1187 Serine/threonine protein kinase 83 1e-15
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 83 2e-15
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 83 2e-15
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
YPL209c [D] KOG0580 Serine/threonine protein kinase 82 3e-15
At4g22130 [T] KOG1187 Serine/threonine protein kinase 82 3e-15
At3g12200 [R] KOG0589 Serine/threonine protein kinase 82 3e-15
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 82 3e-15
7302861 [T] KOG0696 Serine/threonine protein kinase 82 3e-15
7292830 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 82 3e-15
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 82 4e-15
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 82 4e-15
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 82 4e-15
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 81 5e-15
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 81 5e-15
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 81 5e-15
At3g15220 [T] KOG0201 Serine/threonine protein kinase 81 5e-15
At2g02800 [T] KOG1187 Serine/threonine protein kinase 81 5e-15
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 81 5e-15
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 81 6e-15
At5g11015 [T] KOG1187 Serine/threonine protein kinase 81 6e-15
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 81 6e-15
At1g66930 [T] KOG1187 Serine/threonine protein kinase 81 6e-15
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 80 8e-15
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 80 8e-15
At1g53165 [T] KOG0201 Serine/threonine protein kinase 80 8e-15
7303111 [T] KOG0695 Serine/threonine protein kinase 80 8e-15
7292829 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kina... 80 8e-15
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 80 8e-15
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 80 8e-15
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 80 1e-14
SPAC1D4.13 [T] KOG0581 Mitogen-activated protein kinase kinase (... 80 1e-14
At3g07070 [T] KOG1187 Serine/threonine protein kinase 80 1e-14
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 80 1e-14
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 80 1e-14
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 79 2e-14
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 79 2e-14
CE28218 [D] KOG0588 Serine/threonine protein kinase 79 2e-14
At1g14370 [T] KOG1187 Serine/threonine protein kinase 79 2e-14
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 79 2e-14
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 79 2e-14
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 79 2e-14
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 79 2e-14
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 79 2e-14
Hs21735544 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 79 2e-14
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 79 2e-14
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 79 2e-14
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 79 3e-14
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 79 3e-14
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 79 3e-14
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 79 3e-14
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 79 3e-14
Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 79 3e-14
Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (... 79 3e-14
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 79 3e-14
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 79 3e-14
At1g70740 [T] KOG1187 Serine/threonine protein kinase 79 3e-14
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 79 3e-14
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 78 4e-14
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 78 4e-14
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 78 4e-14
At3g24540 [T] KOG1187 Serine/threonine protein kinase 78 4e-14
Hs21735542 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 78 5e-14
Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (... 78 5e-14
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 78 5e-14
CE07399 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 78 5e-14
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 78 5e-14
At5g38260 [T] KOG1187 Serine/threonine protein kinase 78 5e-14
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 78 5e-14
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 78 5e-14
7290147 [T] KOG0583 Serine/threonine protein kinase 78 5e-14
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 77 7e-14
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 7e-14
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 77 9e-14
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 77 9e-14
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 77 9e-14
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 9e-14
At3g13690 [T] KOG1187 Serine/threonine protein kinase 77 9e-14
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 9e-14
7300224 [T] KOG0201 Serine/threonine protein kinase 77 9e-14
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 77 1e-13
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 1e-13
At5g56790 [T] KOG1187 Serine/threonine protein kinase 77 1e-13
At3g19300 [T] KOG1187 Serine/threonine protein kinase 77 1e-13
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 77 1e-13
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 76 2e-13
CE25437 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 76 2e-13
At5g54380 [T] KOG1187 Serine/threonine protein kinase 76 2e-13
At5g35960 [T] KOG1187 Serine/threonine protein kinase 76 2e-13
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 76 2e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 76 2e-13
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 76 2e-13
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 76 2e-13
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 76 2e-13
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 76 2e-13
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 76 2e-13
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 76 2e-13
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 76 2e-13
At1g24030 [T] KOG1187 Serine/threonine protein kinase 76 2e-13
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 75 3e-13
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 75 3e-13
At5g12000 [T] KOG1187 Serine/threonine protein kinase 75 3e-13
At5g07070 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
At3g28690 [T] KOG1187 Serine/threonine protein kinase 75 3e-13
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 75 4e-13
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 75 4e-13
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 75 4e-13
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 4e-13
7300559 [T] KOG4279 Serine/threonine protein kinase 75 4e-13
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 75 5e-13
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 75 5e-13
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 75 5e-13
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 75 5e-13
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 75 5e-13
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 75 5e-13
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 75 5e-13
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 75 5e-13
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 75 5e-13
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 75 5e-13
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 75 5e-13
CE17354 [T] KOG0694 Serine/threonine protein kinase 75 5e-13
CE17353 [T] KOG0694 Serine/threonine protein kinase 75 5e-13
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 75 5e-13
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 75 5e-13
At5g60080 [T] KOG1187 Serine/threonine protein kinase 75 5e-13
At5g39030 [T] KOG1187 Serine/threonine protein kinase 75 5e-13
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 75 5e-13
At3g24550 [T] KOG1187 Serine/threonine protein kinase 75 5e-13
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 74 6e-13
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 74 6e-13
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 74 6e-13
CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 74 6e-13
At5g58940 [T] KOG1187 Serine/threonine protein kinase 74 6e-13
At3g55450 [T] KOG1187 Serine/threonine protein kinase 74 6e-13
At3g26940 [T] KOG1187 Serine/threonine protein kinase 74 6e-13
At3g18810 [T] KOG1187 Serine/threonine protein kinase 74 6e-13
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 74 6e-13
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 6e-13
At1g76370 [T] KOG1187 Serine/threonine protein kinase 74 6e-13
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 74 6e-13
7302860 [T] KOG0696 Serine/threonine protein kinase 74 6e-13
7294217 [D] KOG0588 Serine/threonine protein kinase 74 6e-13
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 74 8e-13
YDR523c [T] KOG0201 Serine/threonine protein kinase 74 8e-13
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 74 8e-13
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 74 8e-13
CE04493 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 74 8e-13
CE02074 [T] KOG0986 G protein-coupled receptor kinase 74 8e-13
At5g58380 [T] KOG0583 Serine/threonine protein kinase 74 8e-13
At4g30960 [T] KOG0583 Serine/threonine protein kinase 74 8e-13
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 74 8e-13
At2g28930 [T] KOG1187 Serine/threonine protein kinase 74 8e-13
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 8e-13
At1g28390 [T] KOG1187 Serine/threonine protein kinase 74 8e-13
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 74 8e-13
7297776 [D] KOG0580 Serine/threonine protein kinase 74 8e-13
SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2 74 1e-12
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 74 1e-12
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 74 1e-12
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 74 1e-12
CE23001 [R] KOG0589 Serine/threonine protein kinase 74 1e-12
CE15235 [R] KOG0589 Serine/threonine protein kinase 74 1e-12
CE05274 [T] KOG0690 Serine/threonine protein kinase 74 1e-12
At5g66790 [T] KOG1187 Serine/threonine protein kinase 74 1e-12
At5g42120 [T] KOG1187 Serine/threonine protein kinase 74 1e-12
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
At2g42960 [T] KOG1187 Serine/threonine protein kinase 74 1e-12
7302570 [R] KOG0586 Serine/threonine protein kinase 74 1e-12
7297611 [T] KOG0614 cGMP-dependent protein kinase 74 1e-12
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 74 1e-12
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 73 1e-12
YJL128c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 73 1e-12
Hs5803143 [T] KOG0192 Tyrosine kinase specific for activated (GT... 73 1e-12
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 73 1e-12
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 73 1e-12
CE26710 [T] KOG0198 MEKK and related serine/threonine protein ki... 73 1e-12
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 73 1e-12
At5g57670 [T] KOG1187 Serine/threonine protein kinase 73 1e-12
At5g10520 [T] KOG1187 Serine/threonine protein kinase 73 1e-12
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 73 1e-12
At1g11140 [T] KOG1187 Serine/threonine protein kinase 73 1e-12
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 73 1e-12
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 73 1e-12
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 73 2e-12
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 73 2e-12
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 73 2e-12
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 73 2e-12
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 73 2e-12
Hs21729899 [T] KOG0581 Mitogen-activated protein kinase kinase (... 73 2e-12
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 73 2e-12
At5g65530 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 2e-12
At4g35030 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
At4g34440 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 73 2e-12
At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GT... 73 2e-12
At1g56720 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
At1g55200 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
At1g49270 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
At1g07570 [T] KOG1187 Serine/threonine protein kinase 73 2e-12
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 73 2e-12
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 73 2e-12
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 73 2e-12
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 72 2e-12
Hs22055520 [R] KOG0584 Serine/threonine protein kinase 72 2e-12
At5g39020 [T] KOG1187 Serine/threonine protein kinase 72 2e-12
At5g18910 [T] KOG1187 Serine/threonine protein kinase 72 2e-12
At3g18750 [R] KOG0584 Serine/threonine protein kinase 72 2e-12
At2g18470 [T] KOG1187 Serine/threonine protein kinase 72 2e-12
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 2e-12
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 72 2e-12
At1g51870 [T] KOG1187 Serine/threonine protein kinase 72 2e-12
7301734 [T] KOG0694 Serine/threonine protein kinase 72 2e-12
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 72 3e-12
Hs4557681 [T] KOG0197 Tyrosine kinases 72 3e-12
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 72 3e-12
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 72 3e-12
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 72 3e-12
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 72 3e-12
At5g38240 [T] KOG1187 Serine/threonine protein kinase 72 3e-12
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
At1g52290 [T] KOG1187 Serine/threonine protein kinase 72 3e-12
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 72 4e-12
Hs4504357 [T] KOG0197 Tyrosine kinases 72 4e-12
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 72 4e-12
Hs13653487 [T] KOG0197 Tyrosine kinases 72 4e-12
Hs12711660 [R] KOG0584 Serine/threonine protein kinase 72 4e-12
CE29298 [T] KOG0690 Serine/threonine protein kinase 72 4e-12
CE15612 [T] KOG0690 Serine/threonine protein kinase 72 4e-12
At2g26980 [T] KOG0583 Serine/threonine protein kinase 72 4e-12
At1g72540 [T] KOG1187 Serine/threonine protein kinase 72 4e-12
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 72 4e-12
7300098 [T] KOG4250 TANK binding protein kinase TBK1 72 4e-12
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 71 5e-12
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 71 5e-12
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 71 5e-12
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 71 5e-12
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 71 5e-12
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 71 5e-12
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 71 5e-12
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 71 5e-12
CE29092 [T] KOG0694 Serine/threonine protein kinase 71 5e-12
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 71 5e-12
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 71 5e-12
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 5e-12
At4g23240 [T] KOG1187 Serine/threonine protein kinase 71 5e-12
At2g39660 [T] KOG1187 Serine/threonine protein kinase 71 5e-12
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 71 5e-12
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 71 5e-12
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 71 5e-12
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 71 5e-12
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 71 7e-12
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 71 7e-12
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 71 7e-12
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 71 7e-12
CE24971 [T] KOG0660 Mitogen-activated protein kinase 71 7e-12
CE01583 [T] KOG0660 Mitogen-activated protein kinase 71 7e-12
At5g59700 [T] KOG1187 Serine/threonine protein kinase 71 7e-12
At5g01810 [T] KOG0583 Serine/threonine protein kinase 71 7e-12
At3g24400 [T] KOG1187 Serine/threonine protein kinase 71 7e-12
At3g17420 [T] KOG1187 Serine/threonine protein kinase 71 7e-12
At2g34180 [T] KOG0583 Serine/threonine protein kinase 71 7e-12
At2g16750 [T] KOG1187 Serine/threonine protein kinase 71 7e-12
At1g67000 [T] KOG1187 Serine/threonine protein kinase 71 7e-12
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 7e-12
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 70 9e-12
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 70 9e-12
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 70 9e-12
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 70 9e-12
At5g15080 [T] KOG1187 Serine/threonine protein kinase 70 9e-12
At4g31110 [T] KOG1187 Serine/threonine protein kinase 70 9e-12
At4g02010 [T] KOG1187 Serine/threonine protein kinase 70 9e-12
At3g01300 [T] KOG1187 Serine/threonine protein kinase 70 9e-12
At2g18890 [T] KOG1187 Serine/threonine protein kinase 70 9e-12
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 70 9e-12
7299536 [D] KOG0580 Serine/threonine protein kinase 70 9e-12
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 70 1e-11
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 70 1e-11
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 70 1e-11
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 70 1e-11
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
CE18646 [T] KOG0690 Serine/threonine protein kinase 70 1e-11
CE06119 [T] KOG0194 Protein tyrosine kinase 70 1e-11
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 70 1e-11
CE03979 [T] KOG0614 cGMP-dependent protein kinase 70 1e-11
At5g18500 [T] KOG1187 Serine/threonine protein kinase 70 1e-11
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
At2g20300 [T] KOG1187 Serine/threonine protein kinase 70 1e-11
At1g11050 [T] KOG1187 Serine/threonine protein kinase 70 1e-11
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 70 1e-11
YDR283c [J] KOG1035 eIF-2alpha kinase GCN2 70 1e-11
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 70 1e-11
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 70 1e-11
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 70 1e-11
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 70 1e-11
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 1e-11
At2g45490 [D] KOG0580 Serine/threonine protein kinase 70 1e-11
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
At1g32320 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 70 1e-11
At1g29230 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
At1g16670 [T] KOG1187 Serine/threonine protein kinase 70 1e-11
At1g01540 [T] KOG1187 Serine/threonine protein kinase 70 1e-11
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 69 2e-11
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 69 2e-11
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 69 2e-11
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 69 2e-11
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 69 2e-11
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 69 2e-11
CE09689 [T] KOG0194 Protein tyrosine kinase 69 2e-11
At5g26150 [T] KOG1187 Serine/threonine protein kinase 69 2e-11
At5g13160 [T] KOG1187 Serine/threonine protein kinase 69 2e-11
At4g14780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 2e-11
At3g59110 [T] KOG1187 Serine/threonine protein kinase 69 2e-11
At3g58640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 2e-11
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 2e-11
At1g78530 [T] KOG1187 Serine/threonine protein kinase 69 2e-11
YGR040w [T] KOG0660 Mitogen-activated protein kinase 69 3e-11
YBL016w [T] KOG0660 Mitogen-activated protein kinase 69 3e-11
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 69 3e-11
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 69 3e-11
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 69 3e-11
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 69 3e-11
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 69 3e-11
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 69 3e-11
CE27768 [R] KOG0586 Serine/threonine protein kinase 69 3e-11
CE23838 [R] KOG0586 Serine/threonine protein kinase 69 3e-11
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 69 3e-11
At4g34500 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At4g02630 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At4g01330 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At3g58690 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At3g51990 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At2g11520 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 69 3e-11
At1g10620 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 69 3e-11
At1g01140 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
7302464 [R] KOG0586 Serine/threonine protein kinase 69 3e-11
7294770 [T] KOG0603 Ribosomal protein S6 kinase 69 3e-11
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 69 3e-11
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 69 3e-11
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 69 3e-11
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 69 3e-11
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 69 3e-11
CE19898 [T] KOG0614 cGMP-dependent protein kinase 69 3e-11
CE19897 [T] KOG0614 cGMP-dependent protein kinase 69 3e-11
CE17343 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
At3g59830 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 3e-11
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 69 3e-11
At1g25390 [T] KOG1187 Serine/threonine protein kinase 69 3e-11
At1g05100 [T] KOG0198 MEKK and related serine/threonine protein ... 69 3e-11
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 69 3e-11
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 69 3e-11
7290249 [R] KOG0586 Serine/threonine protein kinase 69 3e-11
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 68 4e-11
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 68 4e-11
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 68 4e-11
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 68 4e-11
At5g02800 [T] KOG1187 Serine/threonine protein kinase 68 4e-11
At4g00960 [T] KOG1187 Serine/threonine protein kinase 68 4e-11
At3g20530 [T] KOG1187 Serine/threonine protein kinase 68 4e-11
At2g07180 [T] KOG1187 Serine/threonine protein kinase 68 4e-11
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 68 4e-11
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 68 4e-11
7293601 [T] KOG0577 Serine/threonine protein kinase 68 4e-11
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 68 4e-11
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 68 4e-11
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 68 6e-11
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 68 6e-11
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 68 6e-11
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 68 6e-11
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 68 6e-11
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 68 6e-11
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 68 6e-11
CE01405 [T] KOG0577 Serine/threonine protein kinase 68 6e-11
At5g25110 [T] KOG0583 Serine/threonine protein kinase 68 6e-11
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 68 6e-11
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 6e-11
At2g25090 [T] KOG0583 Serine/threonine protein kinase 68 6e-11
At1g76360 [T] KOG1187 Serine/threonine protein kinase 68 6e-11
At1g70460 [T] KOG1187 Serine/threonine protein kinase 68 6e-11
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 68 6e-11
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 67 7e-11
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 67 7e-11
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 67 7e-11
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 67 7e-11
Hs4505055 [T] KOG0197 Tyrosine kinases 67 7e-11
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 67 7e-11
Hs15277312 [R] KOG0584 Serine/threonine protein kinase 67 7e-11
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 67 7e-11
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 67 7e-11
At5g15730 [T] KOG1187 Serine/threonine protein kinase 67 7e-11
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 7e-11
At3g46290 [T] KOG1187 Serine/threonine protein kinase 67 7e-11
At2g23200 [T] KOG1187 Serine/threonine protein kinase 67 7e-11
At1g74490 [T] KOG1187 Serine/threonine protein kinase 67 7e-11
At1g09440 [T] KOG1187 Serine/threonine protein kinase 67 7e-11
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 67 7e-11
YMR139w [G] KOG0658 Glycogen synthase kinase-3 67 1e-10
YDR507c [D] KOG0588 Serine/threonine protein kinase 67 1e-10
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 67 1e-10
YBL105c [T] KOG0694 Serine/threonine protein kinase 67 1e-10
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 67 1e-10
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 67 1e-10
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 67 1e-10
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 67 1e-10
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 1e-10
Hs22046122 [OUT] KOG0595 Serine/threonine-protein kinase involve... 67 1e-10
Hs20428652 [T] KOG0197 Tyrosine kinases 67 1e-10
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 1e-10
At4g32710 [T] KOG1187 Serine/threonine protein kinase 67 1e-10
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 67 1e-10
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 67 1e-10
>YJL187c [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 819
Score = 536 bits (1382), Expect = e-152
Identities = 340/798 (42%), Positives = 431/798 (53%), Gaps = 166/798 (20%)
Query: 67 SNNSNNLKFYSEPLSSRSNSNDTPLGLTRSVGVLNLSLETETPDVKDQKF---------N 117
S +N LKFY P S+ LTRS G LNLSL + KF
Sbjct: 44 STPTNKLKFY--PYSNNK--------LTRSTGTLNLSLSNTALSEANSKFLGKIEEEEEE 93
Query: 118 EENQSHIDSRVPQLQRPLIXXXXXXXXXXXLKRTVSKTGFNISSPFSKNNAAYLKSWHST 177
EE +S +++R KR+ KT +SP S + + W
Sbjct: 94 EEEGKDEESVDSRIKRWSPFHENESVTTPITKRSAEKT----NSPISLKQ--WNQRWFPK 147
Query: 178 NAATSSDLXXXXXXXXXXXXXXEAKPDPVAFQSSGLISKMKQ--TILPKKLTIPDTPVKK 235
N A + + AKP+ AF SSGL+SKM ++ P KL IP+TPVKK
Sbjct: 148 NDARTENTSSSSSYSV-------AKPNQSAFTSSGLVSKMSMDTSLYPAKLRIPETPVKK 200
Query: 236 SPLV------------SRHSDQELLDTPI-------LEHSSIMS-AQNQTTFPTMYDSQL 275
SPLV S+++ L +P+ L+ + S + + P+++ +
Sbjct: 201 SPLVEGRDHKHVHLSSSKNASSSLSVSPLNFVEDNNLQEDLLFSDSPSSKALPSIHVPTI 260
Query: 276 FKSP-------------PMINTVLPXXXXXXXXXXXXXXXXXXK---------IVKNTEL 313
SP N + P K I+KN EL
Sbjct: 261 DSSPLSEAKYHAHDRHNNQTNILSPTNSLVTNSSPQTLHSNKFKKIKRARNSVILKNREL 320
Query: 314 TSMLRQITDDLYGHDQ-----------ESSIFSPSP----------SKTNLQTPTKTSFD 352
T+ L+Q DDLYG D+ S+ +P P + + TPT+
Sbjct: 321 TNSLQQFKDDLYGTDENFPPPIIISSHHSTRKNPQPYQFRGRYDNDTDEEISTPTRRKSI 380
Query: 353 IGPD------------SLAIMTKLRNDPTH------LQPPEKQRSINAS--IMKNPDFHL 392
IG S AI+T + TH P +R + +S + NPD HL
Sbjct: 381 IGATSQTHRESRPLSLSSAIVTNTTSAETHSISSTDSSPLNSKRRLISSNKLSANPDSHL 440
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
KF+NV +GKGQFSTVYQVTF +T KYAIK+++P K+N RIL EI +L+ + + +
Sbjct: 441 FEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQI 500
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
T D EGKEYI+++ISSW + S+YIMTE CENGNLD F+QE VIAK++RLEDWRIWKIIV
Sbjct: 501 TMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIV 560
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYI 572
E+ LALRFIHDSC IVHLDLKPANV+ITFEGNLKL DFGMAT LP+EDKSFENEGDREYI
Sbjct: 561 ELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYI 620
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSSAEIHS 632
APEII D YD++ADIFSLGLM++EIAANV+LPDNG+AWHKLRSGDLSDAGRLSS +IHS
Sbjct: 621 APEIISDCTYDYKADIFSLGLMIVEIAANVVLPDNGNAWHKLRSGDLSDAGRLSSTDIHS 680
Query: 633 SSLFS------------------------------------------NKKDHTNITDITT 650
SLFS N D+ N+ T
Sbjct: 681 ESLFSDITKVDTNDLFDFERDNISGNSNNAGTSTVHNNSNINNPNMNNGNDNNNVNTAAT 740
Query: 651 -------HETKIPAWVPKFLLDGISLERTIRWMIEPDYRDRPSASDLLRTEELEYVELTR 703
+KIPAWVPKFL+DG SLER +RWMIEP+Y RP+A+ +L+TEE YVE+TR
Sbjct: 741 KNRLILHKSSKIPAWVPKFLIDGESLERIVRWMIEPNYERRPTANQILQTEECLYVEMTR 800
Query: 704 KTGAVIHEDDYGPKPEFF 721
GA+I EDD+GPKP+FF
Sbjct: 801 NAGAIIQEDDFGPKPKFF 818
>SPCC18B5.03 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 877
Score = 278 bits (712), Expect = 2e-74
Identities = 198/586 (33%), Positives = 296/586 (49%), Gaps = 69/586 (11%)
Query: 150 RTVSKTGFNISSPFSKNNAAYLKSWHSTNAATSSDLXXXXXXXXXXXXXXEAKPDPVAFQ 209
R+ +T N SS FS N+ S +S + ++ L + KP F
Sbjct: 323 RSHPQTQQNESSLFSDNSMVNSSS-NSFSLFPNATLPNPPSSELLTTPFQQIKPPSQVFM 381
Query: 210 SSGLISKMKQ-------TILPKKLTIPDTPVKKSPLVSRHSDQELLDTPILEHSSIMSAQ 262
S+GL+SK + T LP P TP K S V HS D+P
Sbjct: 382 STGLLSKQHRPRKNINFTPLP-----PSTPSKPSTFVRPHSSST--DSP---------PS 425
Query: 263 NQTTFPTMYDSQLFK--SPPMINTVLPXXXXXXXXXXXXXXXXXXKIVK---NTELTSML 317
T T DS + + P + +P VK N L +
Sbjct: 426 PSTPSNTQTDSYFIQRENTPTNHNSIPTIQLEKSSMDFLRFDPPPSAVKTSHNYGLPFLS 485
Query: 318 RQI-----TDDLYGHDQESSIFSPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQ 372
Q T + + + SI + +++ + A +++ + L
Sbjct: 486 NQRCPATPTRNPFAFENTVSIHMDGRQPSPIKSRNNNQMSFAMEEEADVSQPSSSSFTLS 545
Query: 373 PPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFP-ETGLKYAIKS--VRP 429
P ++ +S + + HL T+F NV+++G G+FS V+QV P E LKYA+K V+
Sbjct: 546 FPS---ALTSSKVSSSTSHLLTRFRNVTLLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKF 602
Query: 430 TKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDA 489
+ NR+LQE+ S+ +G ++IVE + SW H G Y+ E CENG+LD
Sbjct: 603 SGPKERNRLLQEV--------SIQRALKGHDHIVELMDSWEHGGFLYMQVELCENGSLDR 654
Query: 490 FIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLAD 549
F++E + RL+++R+WKI+VE+ L L+FIH + VHLDLKPANV+ITFEG LK+ D
Sbjct: 655 FLEEQ--GQLSRLDEFRVWKILVEVALGLQFIHHK-NYVHLDLKPANVMITFEGTLKIGD 711
Query: 550 FGMATKLPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGS 609
FGMA+ P+ + E EGD EYIAPE++ + +YD ADIFSLG+ + E AAN++LPDNG
Sbjct: 712 FGMASVWPVP-RGMEREGDCEYIAPEVLANHLYDKPADIFSLGITVFEAAANIVLPDNGQ 770
Query: 610 AWHKLRSGDLSDAGRLSSAEIHSSSLFSNKKDHTNITDITTHETKIPAWVPKFLLDGISL 669
+W KLRSGDLSDA RLSS + N + +T+ + PA ++ L
Sbjct: 771 SWQKLRSGDLSDAPRLSSTD--------------NGSSLTSSSRETPA---NSIIGQGGL 813
Query: 670 ERTIRWMIEPDYRDRPSASDLLRTEELEYVELTRKTGAVIHEDDYG 715
+R + WM+ P+ R+RP+ +L T+E+ +VE+ RK GA+I+E +G
Sbjct: 814 DRVVEWMLSPEPRNRPTIDQILATDEVCWVEMRRKAGAIIYEGIHG 859
>SPBC660.14 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 581
Score = 184 bits (468), Expect = 3e-46
Identities = 114/325 (35%), Positives = 172/325 (52%), Gaps = 39/325 (12%)
Query: 392 LTTKFSNVSIMGKGQFSTVYQVTF--PETGLKYAIKSVRPTKHNFTN--RILQEINMLST 447
L +F V + + FS VY V+ P T Y +K ++ FT R LQE+++L
Sbjct: 285 LRIRFQQVKPIHESDFSFVYHVSSINPPTETVYVVKMLKKNAAKFTGKERHLQEVSILQR 344
Query: 448 IQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI 507
+Q ++V ++ WS+ + ++ ++CENG+L F+ E + Q ++ +R+
Sbjct: 345 LQAC--------PFVVNLVNVWSYNDNIFLQLDYCENGDLSLFLSE--LGLLQVMDPFRV 394
Query: 508 WKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEG 567
WK++ ++ AL FIH VHLD+KP+NVLIT +GNLKL DFG+AT LP+ + EG
Sbjct: 395 WKMLFQLTQALNFIH-LLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSM-VDLEG 452
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSS 627
DR YIAPEI+ Y AD++SLGL MIE A NV+LP+NG W +LRSGD S+ L
Sbjct: 453 DRVYIAPEILASHNYGKPADVYSLGLSMIEAATNVVLPENGVEWQRLRSGDYSNLPNLKD 512
Query: 628 AEIHSSSLFSNKKDHTNITDITTHETKIPAWVPKFLLDGISLERTIRWMIEPDYRDRPSA 687
+ K+ I + E SL+ ++ M P RP+
Sbjct: 513 LLL--------SKEKVQINKVRCAE---------------SLQCLLQRMTHPYVDCRPTT 549
Query: 688 SDLLRTEELEYVELTRKTGAVIHED 712
DLL E+ ++ + A+I+ED
Sbjct: 550 QDLLAMPEMIFISEHSQKAAIIYED 574
>7295431 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 770
Score = 129 bits (324), Expect = 2e-29
Identities = 93/318 (29%), Positives = 145/318 (45%), Gaps = 57/318 (17%)
Query: 391 HLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRI--LQEINMLSTI 448
H F ++ +G+G F V+QV G YA+K + R L+E+
Sbjct: 97 HFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYE-- 154
Query: 449 QDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIW 508
+ G E + FI +W Y+ E C E + + QR+ + RIW
Sbjct: 155 ------EFSGHENCIRFIRAWEQYDRLYMQMELCRES------LEQYLLRCQRIPEERIW 202
Query: 509 KIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNL-KLADFGMATKLPIEDKSFENEG 567
I++++ L+ +HD +++HLD+K NVLI + KLADFG+ + + EG
Sbjct: 203 HILLDLLRGLKSLHDR-NLIHLDIKLDNVLIGEDDETCKLADFGLVIDVDRANSHHATEG 261
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSS 627
D Y+APEI++ G + ADIFSLG+ M+E+A + LP NG WH+LR G L +
Sbjct: 262 DSRYMAPEILQ-GHFSKAADIFSLGIAMLELACYMDLPSNGPLWHELRHGILPEE----- 315
Query: 628 AEIHSSSLFSNKKDHTNITDITTHETKIPAWVPKFLLDGISLERTIRWMIEPDYRDRPSA 687
F NK + L+ I+ M++PD RP+A
Sbjct: 316 --------FINK-------------------------ISLELQSVIKSMMKPDPAQRPTA 342
Query: 688 SDLLRTEELEYVELTRKT 705
LL +L+Y++ RK+
Sbjct: 343 EQLLSHPKLQYLQKKRKS 360
>CE14884_1 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 415
Score = 120 bits (300), Expect = 1e-26
Identities = 80/290 (27%), Positives = 143/290 (48%), Gaps = 31/290 (10%)
Query: 336 PSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQRSINASIMKNPDFHLTTK 395
P+P PT++ + + +S+ ++ + P L+ P+ + N
Sbjct: 56 PAPKMIKTMPPTRSIWSVRKESVPLLVTPQG-PKPLESPKYDHT-------NAQSFFEQV 107
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIK-SVRPTK-HNFTNRILQEINMLSTIQDSVT 453
F I+G+G F V+ E YA+K S+ P + H+ + E +M+ +
Sbjct: 108 FQIDEIIGRGSFGEVFAARCREDSQLYAVKVSLAPIRQHSISKYREAESHMIIPPHKN-- 165
Query: 454 NDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVE 513
+V+F +W G YI TE C+ L ++H + + + IW I V+
Sbjct: 166 --------LVKFYRAWEETGRLYIQTELCDQSLLKYCTEKHALPEDE------IWNIFVD 211
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL--PIEDKSFENEGDREY 571
+ A+ +H + ++H D+KP N+ +T + KL DFG+ L P + KS E EGD +Y
Sbjct: 212 LLQAVHHLHSN-DMIHDDIKPENIFLTKDMICKLGDFGLVINLKNPNDVKSAE-EGDSKY 269
Query: 572 IAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSD 621
+APE++ +G +DIFSLG+ ++E ++ +P NG +WH++R+G + D
Sbjct: 270 LAPEVL-NGRPTKSSDIFSLGMTILEATTDLDVPSNGDSWHQIRNGQIPD 318
>HsM4758928 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 499
Score = 116 bits (291), Expect = 1e-25
Identities = 77/235 (32%), Positives = 117/235 (49%), Gaps = 19/235 (8%)
Query: 388 PDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIK-SVRPTKHNFTN-RILQEINML 445
P+ F +S +G G + V++V E G YA+K S+ P + R L E+
Sbjct: 102 PESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVG-- 159
Query: 446 STIQDSVTNDTEGKE-YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED 504
+++ G+ V +W G Y+ TE C +Q+H A L +
Sbjct: 160 -------SHEKVGQHPCCVRLEQAWEEGGILYLQTELCGPS-----LQQHCEAWGASLPE 207
Query: 505 WRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFE 564
++W + + LAL +H S +VHLD+KPAN+ + G KL DFG+ +L
Sbjct: 208 AQVWGYLRDTLLALAHLH-SQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTAGAGEV 266
Query: 565 NEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDL 619
EGD Y+APE+++ G Y AD+FSLGL ++E+A N+ LP G W +LR G L
Sbjct: 267 QEGDPRYMAPELLQ-GSYGTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYL 320
>Hs21361083 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 499
Score = 116 bits (291), Expect = 1e-25
Identities = 77/235 (32%), Positives = 117/235 (49%), Gaps = 19/235 (8%)
Query: 388 PDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIK-SVRPTKHNFTN-RILQEINML 445
P+ F +S +G G + V++V E G YA+K S+ P + R L E+
Sbjct: 102 PESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVG-- 159
Query: 446 STIQDSVTNDTEGKE-YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED 504
+++ G+ V +W G Y+ TE C +Q+H A L +
Sbjct: 160 -------SHEKVGQHPCCVRLEQAWEEGGILYLQTELCGPS-----LQQHCEAWGASLPE 207
Query: 505 WRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFE 564
++W + + LAL +H S +VHLD+KPAN+ + G KL DFG+ +L
Sbjct: 208 AQVWGYLRDTLLALAHLH-SQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGTAGAGEV 266
Query: 565 NEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDL 619
EGD Y+APE+++ G Y AD+FSLGL ++E+A N+ LP G W +LR G L
Sbjct: 267 QEGDPRYMAPELLQ-GSYGTAADVFSLGLTILEVACNMELPHGGEGWQQLRQGYL 320
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 112 bits (279), Expect = 3e-24
Identities = 81/306 (26%), Positives = 146/306 (47%), Gaps = 61/306 (19%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRI--LQEINMLSTIQDSVTNDT 456
V +G+G F + + V KY +K +R K ++ +QE++++S ++
Sbjct: 18 VEQIGRGAFGSAFLVIHKSERRKYVVKKIRLAKQTERCKLAAIQEMSLISKLKSP----- 72
Query: 457 EGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEH--VIAKQQRLEDWRIWKIIVEI 514
YIVE+ SW K I+T +CE G++ I++ V A +++L W +V++
Sbjct: 73 ----YIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRW-----MVQL 123
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAP 574
LA+ ++H++ ++H DLK +N+ +T E ++L DFG+A L +D + G Y+ P
Sbjct: 124 LLAIDYLHNN-RVLHRDLKCSNIFLTKENEVRLGDFGLAKLLGKDDLASSMVGTPNYMCP 182
Query: 575 EIIRDGIYDFRADIFSLGLMMIEIAAN---VILPDNGSAWHKLRSGDLSDAGRLSSAEIH 631
E++ D Y +++DI+SLG M E+AA+ PD + +K+ LS
Sbjct: 183 ELLADIPYGYKSDIWSLGCCMFEVAAHQPAFKAPDMAALINKINRSSLS----------- 231
Query: 632 SSSLFSNKKDHTNITDITTHETKIPAWVPKFLLDGISLERTIRWMIEPDYRDRPSASDLL 691
P ++ SL+R I+ M+ + RP+A++LL
Sbjct: 232 ----------------------------PLPVMYSSSLKRLIKSMLRKNPEHRPTAAELL 263
Query: 692 RTEELE 697
R L+
Sbjct: 264 RHPHLQ 269
>ECU08g1620 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 363
Score = 106 bits (264), Expect = 1e-22
Identities = 65/202 (32%), Positives = 107/202 (52%), Gaps = 25/202 (12%)
Query: 437 RILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVI 496
RI E++ S I++ EY+V++ W +G +I E+C G L +I E
Sbjct: 135 RISGELDRKSRIREIEMLKKIDSEYVVKYYDFWESRGYLFIELEYCNIGTLRDYIHEVYF 194
Query: 497 AKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLI----------------- 539
K+ + K++ E+ L IH SC+IVHLDLKP N+L+
Sbjct: 195 LKKSKFSPEITRKMMYELASGLEAIH-SCNIVHLDLKPENILMKSIISREKCPGRCQCMF 253
Query: 540 -TFEGN--LKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMI 596
T G+ K++DF ++ E + +++GD+ Y+APE+++D I +DI+SLGL+ +
Sbjct: 254 PTDPGSFVFKISDFNISR---YEGEDIDDDGDKRYMAPEVLQD-ICTKASDIYSLGLIYL 309
Query: 597 EIAANVILPDNGSAWHKLRSGD 618
E+ A +ILP +G +W +LR D
Sbjct: 310 EVIAEIILPKSGDSWMRLRRND 331
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 105 bits (262), Expect = 2e-22
Identities = 71/207 (34%), Positives = 109/207 (52%), Gaps = 20/207 (9%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEG 458
V +G G F VY+ ETG A K + + EI +L+T
Sbjct: 39 VGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHP------- 91
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
YIV+ + ++ H G +IM EFC G +DA + E + L + +I + ++ AL
Sbjct: 92 --YIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLE----LDRGLTEPQIQVVCRQMLEAL 145
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDREYIAPEII 577
F+H S I+H DLK NVL+T EG+++LADFG++ K L K G ++APE++
Sbjct: 146 NFLH-SKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVV 204
Query: 578 -----RDGIYDFRADIFSLGLMMIEIA 599
+D YD++ADI+SLG+ +IE+A
Sbjct: 205 MCETMKDTPYDYKADIWSLGITLIEMA 231
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 103 bits (256), Expect = 1e-21
Identities = 73/255 (28%), Positives = 132/255 (51%), Gaps = 21/255 (8%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFT--NRILQEINMLSTIQDSVTNDT 456
+++MG G F T Y+V TG +A K + + + + ++ EI++L +Q N
Sbjct: 22 LAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHP--NIV 79
Query: 457 EGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICL 516
+ ++V S YI+ E C G+L +Q +++QR E+ IW+++ ++C
Sbjct: 80 QYYHHLVN-----REAKSVYIVMECCAGGDLAQIVQR-ARSQRQRFEEPYIWRVLFQLCR 133
Query: 517 ALRFIHDSC---SIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREY 571
AL+ H+ +I+H D+KPAN+ + GN KL DFG+A L D+SF G Y
Sbjct: 134 ALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLR-RDQSFAASFVGTPHY 192
Query: 572 IAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAW----HKLRSGDLSDAGRLSS 627
++PE+++ YD ++D++++G ++ E+ A + P G A+ K+ G+ S + S
Sbjct: 193 MSPELVKGRKYDRKSDVWAVGCLVYEMCA-LRPPFRGRAFDQLSEKIAQGEFSRIPAIYS 251
Query: 628 AEIHSSSLFSNKKDH 642
++ F DH
Sbjct: 252 TDLQEIIAFMLAVDH 266
>CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kinase MKK4
Length = 363
Score = 97.8 bits (242), Expect = 5e-20
Identities = 77/263 (29%), Positives = 127/263 (48%), Gaps = 20/263 (7%)
Query: 348 KTSFDIGPDSLAIM-TKLRNDPTHLQPPEKQ--RSINASIMKNPDFHLTTKFSNVSI--- 401
+ S + P SL+ T L + PE+ RS++ +K PD FS+ ++
Sbjct: 10 RNSMSLRPTSLSTRPTSLSVNGNEKTLPEESVLRSLSTGTLKYPDDEHLYTFSSANLQDL 69
Query: 402 --MGKGQFSTVYQVTFPETGLKYAIKSVRPTK--HNFTNRILQEINMLSTIQDSVTNDTE 457
+G G F TVY++ ETG A+K +R H R+L+E D++ +
Sbjct: 70 GAIGNGNFGTVYKMRHKETGKLIAVKRIRCNNIGHREQIRLLRE-------HDTIVKSEK 122
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
G IV+F + +G +I E + ++D + + K RL + + I V A
Sbjct: 123 GPN-IVKFYGAIFSEGDCWICMELMDI-SMDLLYKRVYMVKNSRLNENVVGHITVCTVDA 180
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPE-I 576
L ++ I+H D+KP+N+L+ G +KL DFG+ +L + G + Y+APE I
Sbjct: 181 LDYLKKELKIIHRDVKPSNILVDGTGAVKLCDFGICGQLEESFAKTHDAGCQPYLAPERI 240
Query: 577 IRDGIYDFRADIFSLGLMMIEIA 599
YD R+D++SLG+ + EIA
Sbjct: 241 TSSDKYDVRSDVWSLGITLYEIA 263
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 97.4 bits (241), Expect = 7e-20
Identities = 66/216 (30%), Positives = 120/216 (55%), Gaps = 22/216 (10%)
Query: 389 DFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLST 447
+ +++ F ++G+G+F VY+ +TG YAIK + + + + +EI L++
Sbjct: 16 EMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLAS 75
Query: 448 IQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI 507
++ ++N I + S+ S +I+ E C G+L + + + ++++ I
Sbjct: 76 LKQ-ISN-------ITRYYGSYLKDTSLWIIMEHCAGGSLRSLL------RPGKIDEKYI 121
Query: 508 WKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE- 566
I+ E+ +AL+ IH +++H D+K ANVLIT EGN+KL DFG+A + + S +
Sbjct: 122 GVIMRELLVALKCIHKD-NVIHRDIKAANVLITNEGNVKLCDFGVAAQ--VNQTSLRRQT 178
Query: 567 --GDREYIAPEIIRDGI-YDFRADIFSLGLMMIEIA 599
G ++APE+I +G+ YD + DI+SLG+ EIA
Sbjct: 179 MAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIA 214
>Hs4507917 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 646
Score = 95.1 bits (235), Expect = 3e-19
Identities = 77/282 (27%), Positives = 138/282 (48%), Gaps = 46/282 (16%)
Query: 374 PEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIK-SVRPTKH 432
P K+ +I S MK+ TT+F + +G G+F +V++ G YAIK S +P
Sbjct: 280 PAKRITITESNMKS---RYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKP--- 333
Query: 433 NFTNRILQEINMLSTIQDSVTNDTEGKE-YIVEFISSWSHKGSFYIMTEFCENGNL-DAF 490
+ ++ + +++ + G+ ++V + S+W+ I E+C G+L DA
Sbjct: 334 -----LAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAI 388
Query: 491 IQEHVIA---KQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITF------ 541
+ + I K+ L+D +++++ LR+IH S S+VH+D+KP+N+ I+
Sbjct: 389 SENYRIMSYFKEAELKD-----LLLQVGRGLRYIH-SMSLVHMDIKPSNIFISRTSIPNA 442
Query: 542 ---EGN----------LKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDGIYDF-RAD 587
EG+ K+ D G T++ EGD ++A E++++ +AD
Sbjct: 443 ASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVE---EGDSRFLANEVLQENYTHLPKAD 499
Query: 588 IFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSSAE 629
IF+L L ++ A LP NG WH++R G L ++ S E
Sbjct: 500 IFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQE 541
>Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 393
Score = 94.7 bits (234), Expect = 4e-19
Identities = 69/267 (25%), Positives = 126/267 (46%), Gaps = 28/267 (10%)
Query: 346 PTKTSFDIGPDSLAI--MTKLRNDPTHLQPPEKQRSINASIMKNPDFHLTTK-------- 395
PT + PD A+ + + LQ ++ ++ K + LT K
Sbjct: 6 PTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKD 65
Query: 396 --FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSV 452
F +S +G G V++V+ +GL A K + K N+I++E+ +L
Sbjct: 66 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSP- 124
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
YIV F ++ G I E + G+LD V+ K R+ + + K+ +
Sbjct: 125 --------YIVGFYGAFYSDGEISICMEHMDGGSLD-----QVLKKAGRIPEQILGKVSI 171
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYI 572
+ L ++ + I+H D+KP+N+L+ G +KL DFG++ +L I+ + G R Y+
Sbjct: 172 AVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQL-IDSMANSFVGTRSYM 230
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEIA 599
+PE ++ Y ++DI+S+GL ++E+A
Sbjct: 231 SPERLQGTHYSVQSDIWSMGLSLVEMA 257
>At3g44200 [R] KOG0589 Serine/threonine protein kinase
Length = 941
Score = 93.2 bits (230), Expect = 1e-18
Identities = 59/204 (28%), Positives = 108/204 (52%), Gaps = 20/204 (9%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR--ILQEINMLSTIQDSVTNDTEGK 459
+G+G F V KY +K +R + R QE+++++ +Q
Sbjct: 14 IGRGAFGAAILVHHKAERKKYVLKKIRLARQTERCRRSAHQEMSLIARVQHP-------- 65
Query: 460 EYIVEFISSWSHKGSFY-IMTEFCENGNLDAFIQEH--VIAKQQRLEDWRIWKIIVEICL 516
YIVEF +W KG + I+T +CE G++ +++ V +++L W ++ L
Sbjct: 66 -YIVEFKEAWVEKGCYVCIVTGYCEGGDMAELMKKSNGVYFPEEKLCKW-----FTQLLL 119
Query: 517 ALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEI 576
A+ ++H + ++H DLK +N+ +T + +++L DFG+A L +D + G Y+ PE+
Sbjct: 120 AVEYLHSNY-VLHRDLKCSNIFLTKDQDVRLGDFGLAKTLKADDLTSSVVGTPNYMCPEL 178
Query: 577 IRDGIYDFRADIFSLGLMMIEIAA 600
+ D Y F++DI+SLG + E+AA
Sbjct: 179 LADIPYGFKSDIWSLGCCIYEMAA 202
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 92.8 bits (229), Expect = 2e-18
Identities = 67/207 (32%), Positives = 107/207 (51%), Gaps = 17/207 (8%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP---TKHNFTNRILQEINMLSTIQDSV 452
F + ++GKG F VYQV +T YA+K + K N + E N+L V
Sbjct: 412 FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNIL------V 465
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
T ++ +IV S+ Y++T++ G L +Q K+ R + R I
Sbjct: 466 TTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQ-----KEGRFSEDRAKFYIA 520
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYI 572
E+ LAL +HD+ IV+ DLKP N+L+ GN+ L DFG+ +K ++D++ G EY+
Sbjct: 521 ELVLALEHLHDN-DIVYRDLKPENILLDANGNIALCDFGL-SKADLKDRTNTFCGTTEYL 578
Query: 573 APEIIRDGI-YDFRADIFSLGLMMIEI 598
APE++ D Y D +SLG+++ E+
Sbjct: 579 APELLLDETGYTKMVDFWSLGVLIFEM 605
>7299057 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kinase MKK4
Length = 424
Score = 91.7 bits (226), Expect = 4e-18
Identities = 61/203 (30%), Positives = 111/203 (54%), Gaps = 15/203 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPT-KHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G+G F V ++TF + A+K +R T ++L ++ ++ + +
Sbjct: 128 IGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECI-------- 179
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQR-LEDWRIWKIIVEICLALR 519
YIV+F + +G +I E + +LD F + ++ KQQR + + + KI V AL
Sbjct: 180 YIVQFYGALFKEGDCWICMELMDT-SLDKFYK-YIYEKQQRHIPESILAKITVATVNALN 237
Query: 520 FIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEII-- 577
++ + I+H D+KP+N+L+ G++KL DFG++ +L ++ G R Y+APE I
Sbjct: 238 YLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDP 297
Query: 578 -RDGIYDFRADIFSLGLMMIEIA 599
R YD R+D++SLG+ ++E+A
Sbjct: 298 ERAKGYDVRSDVWSLGITLMEVA 320
>HsM4506099 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 318
Score = 91.3 bits (225), Expect = 5e-18
Identities = 61/206 (29%), Positives = 110/206 (52%), Gaps = 15/206 (7%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQEINMLSTIQDSVTNDTE 457
+S +G+G + V +V ++G A+K +R T ++ R+L ++++ D
Sbjct: 38 ISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCF----- 92
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
Y V F + +G +I E + +LD F ++ V+ K + + + +I V I A
Sbjct: 93 ---YTVTFYGALFREGDVWICMELMDT-SLDKFYRK-VLDKNMTIPEDILGEIAVSIVRA 147
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEII 577
L +H S++H D+KP+NVLI EG++K+ DFG++ L + G + Y+APE I
Sbjct: 148 LEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERI 207
Query: 578 RDGI----YDFRADIFSLGLMMIEIA 599
+ Y+ ++D++SLG+ MIE+A
Sbjct: 208 NPELNQKGYNVKSDVWSLGITMIEMA 233
>Hs21618351 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 352
Score = 91.3 bits (225), Expect = 5e-18
Identities = 61/206 (29%), Positives = 110/206 (52%), Gaps = 15/206 (7%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQEINMLSTIQDSVTNDTE 457
+S +G+G + V +V ++G A+K +R T ++ R+L ++++ D
Sbjct: 72 ISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCF----- 126
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
Y V F + +G +I E + +LD F ++ V+ K + + + +I V I A
Sbjct: 127 ---YTVTFYGALFREGDVWICMELMDT-SLDKFYRK-VLDKNMTIPEDILGEIAVSIVRA 181
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEII 577
L +H S++H D+KP+NVLI EG++K+ DFG++ L + G + Y+APE I
Sbjct: 182 LEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERI 241
Query: 578 RDGI----YDFRADIFSLGLMMIEIA 599
+ Y+ ++D++SLG+ MIE+A
Sbjct: 242 NPELNQKGYNVKSDVWSLGITMIEMA 267
>Hs21618349 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 347
Score = 91.3 bits (225), Expect = 5e-18
Identities = 61/206 (29%), Positives = 110/206 (52%), Gaps = 15/206 (7%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQEINMLSTIQDSVTNDTE 457
+S +G+G + V +V ++G A+K +R T ++ R+L ++++ D
Sbjct: 67 ISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCF----- 121
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
Y V F + +G +I E + +LD F ++ V+ K + + + +I V I A
Sbjct: 122 ---YTVTFYGALFREGDVWICMELMDT-SLDKFYRK-VLDKNMTIPEDILGEIAVSIVRA 176
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEII 577
L +H S++H D+KP+NVLI EG++K+ DFG++ L + G + Y+APE I
Sbjct: 177 LEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERI 236
Query: 578 RDGI----YDFRADIFSLGLMMIEIA 599
+ Y+ ++D++SLG+ MIE+A
Sbjct: 237 NPELNQKGYNVKSDVWSLGITMIEMA 262
>Hs21618347 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 318
Score = 91.3 bits (225), Expect = 5e-18
Identities = 61/206 (29%), Positives = 110/206 (52%), Gaps = 15/206 (7%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQEINMLSTIQDSVTNDTE 457
+S +G+G + V +V ++G A+K +R T ++ R+L ++++ D
Sbjct: 38 ISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCF----- 92
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
Y V F + +G +I E + +LD F ++ V+ K + + + +I V I A
Sbjct: 93 ---YTVTFYGALFREGDVWICMELMDT-SLDKFYRK-VLDKNMTIPEDILGEIAVSIVRA 147
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEII 577
L +H S++H D+KP+NVLI EG++K+ DFG++ L + G + Y+APE I
Sbjct: 148 LEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERI 207
Query: 578 RDGI----YDFRADIFSLGLMMIEIA 599
+ Y+ ++D++SLG+ MIE+A
Sbjct: 208 NPELNQKGYNVKSDVWSLGITMIEMA 233
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 91.3 bits (225), Expect = 5e-18
Identities = 73/240 (30%), Positives = 118/240 (48%), Gaps = 27/240 (11%)
Query: 368 PTHLQPPEKQRSINASIMKNP--DFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIK 425
P H PP+ QR N + DF + K +G+GQFS VY+ T A+K
Sbjct: 23 PVH--PPDPQRHPNTLSFRCSLADFQIEKK------IGRGQFSEVYKATCLLDRKTVALK 74
Query: 426 SVRPTKH---NFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFC 482
V+ + ++EI +L + I++++ S+ I+ E
Sbjct: 75 KVQIFEMMDAKARQDCVKEIGLLKQLNHP---------NIIKYLDSFIEDNELNIVLELA 125
Query: 483 ENGNLDAFIQEHVIAKQQRLEDWR-IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITF 541
+ G+L I+ KQ+RL R +WK V++C A+ +H S ++H D+KPANV IT
Sbjct: 126 DAGDLSQMIK--YFKKQKRLIPERTVWKYFVQLCSAVEHMH-SRRVMHRDIKPANVFITA 182
Query: 542 EGNLKLADFGMATKLPIEDKSFEN-EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAA 600
G +KL D G+ E + + G Y++PE I + Y+F++DI+SLG ++ E+AA
Sbjct: 183 TGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA 242
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 90.9 bits (224), Expect = 6e-18
Identities = 59/207 (28%), Positives = 110/207 (52%), Gaps = 26/207 (12%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+G G F VY+ ET + A K + + EI++L++
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHP---------N 90
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
IV+ + ++ ++ + +I+ EFC G +DA + E ++ L + +I + + AL ++
Sbjct: 91 IVKLLDAFYYENNLWILIEFCAGGAVDAVMLE----LERPLTESQIQVVCKQTLDALNYL 146
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDREYIAPEII 577
HD+ I+H DLK N+L T +G++KLADFG++ K ++ + G ++APE++
Sbjct: 147 HDN-KIIHRDLKAGNILFTLDGDIKLADFGVSAK---NTRTIQRRDSFIGTPYWMAPEVV 202
Query: 578 -----RDGIYDFRADIFSLGLMMIEIA 599
+D YD++AD++SLG+ +IE+A
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMA 229
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 90.9 bits (224), Expect = 6e-18
Identities = 66/233 (28%), Positives = 115/233 (49%), Gaps = 17/233 (7%)
Query: 373 PPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP--- 429
PP Q ++ + ++ F +G+GQFS VY+ G+ A+K V+
Sbjct: 11 PPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDL 70
Query: 430 TKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDA 489
++EI++L + ++++ +S+ I+ E + G+L
Sbjct: 71 MDAKARADCIKEIDLLKQLNHP---------NVIKYYASFIEDNELNIVLELADAGDLSR 121
Query: 490 FIQEHVIAKQQRLEDWR-IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLA 548
I+ KQ+RL R +WK V++C AL +H S ++H D+KPANV IT G +KL
Sbjct: 122 MIKH--FKKQKRLIPERTVWKYFVQLCSALEHMH-SRRVMHRDIKPANVFITATGVVKLG 178
Query: 549 DFGMATKLPIEDKSFEN-EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAA 600
D G+ + + + G Y++PE I + Y+F++DI+SLG ++ E+AA
Sbjct: 179 DLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA 231
>Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 400
Score = 90.9 bits (224), Expect = 6e-18
Identities = 58/205 (28%), Positives = 105/205 (50%), Gaps = 16/205 (7%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVTN 454
F +S +G G V +V +GL A K + K N+I++E+ +L
Sbjct: 72 FERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSP--- 128
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
YIV F ++ G I E + G+LD ++E +R+ + + K+ + +
Sbjct: 129 ------YIVGFYGAFYSDGEISICMEHMDGGSLDQVLKE-----AKRIPEEILGKVSIAV 177
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAP 574
L ++ + I+H D+KP+N+L+ G +KL DFG++ +L I+ + G R Y+AP
Sbjct: 178 LRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQL-IDSMANSFVGTRSYMAP 236
Query: 575 EIIRDGIYDFRADIFSLGLMMIEIA 599
E ++ Y ++DI+S+GL ++E+A
Sbjct: 237 ERLQGTHYSVQSDIWSMGLSLVELA 261
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 90.9 bits (224), Expect = 6e-18
Identities = 69/229 (30%), Positives = 113/229 (49%), Gaps = 20/229 (8%)
Query: 374 PEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK-H 432
P ++R + I N F+ +G+G F VY+ TG AIK + +
Sbjct: 10 PAERRKVVKPIEDNSKLDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAE 69
Query: 433 NFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGN-LDAFI 491
+ I QEI +LS +Y+ ++ S+ +I+ E+ G+ LD
Sbjct: 70 DEIEDIQQEIQVLSQCDS---------QYVTKYFGSFLKGSKLWIIMEYLGGGSALD--- 117
Query: 492 QEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFG 551
+ K +L++ I I+ EI L ++H I H D+K ANVL++ G++K+ADFG
Sbjct: 118 ----LTKSGKLDESHIAVILREILKGLEYLHSERKI-HRDIKAANVLVSEHGDVKVADFG 172
Query: 552 MATKLP-IEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
+A +L K G ++APE+I+ YD++ADI+SLG+ IE+A
Sbjct: 173 VAGQLTETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELA 221
>SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 605
Score = 90.5 bits (223), Expect = 8e-18
Identities = 60/206 (29%), Positives = 106/206 (51%), Gaps = 24/206 (11%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFT-NRILQEINMLSTIQDSVTNDTEGKE 460
+GKG + VY+ TG+ A+K +R + T N+I+ E+++L
Sbjct: 326 LGKGNYGVVYKALHQPTGVTMALKEIRLSLEEATFNQIIMELDILHKAVSP--------- 376
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
YIV+F ++ +GS +I E+ + G++D + ++ + + + L+
Sbjct: 377 YIVDFYGAFFVEGSVFICMEYMDAGSMDKLYAGGI------KDEGVLARTAYAVVQGLKT 430
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG 580
+ + +I+H D+KP NVL+ G +KL DFG++ L + S N G + Y+APE IR G
Sbjct: 431 LKEEHNIIHRDVKPTNVLVNSNGQVKLCDFGVSGNL-VASISKTNIGCQSYMAPERIRVG 489
Query: 581 -------IYDFRADIFSLGLMMIEIA 599
Y +AD++SLGL ++E+A
Sbjct: 490 GPTNGVLTYTVQADVWSLGLTILEMA 515
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 90.5 bits (223), Expect = 8e-18
Identities = 65/210 (30%), Positives = 115/210 (53%), Gaps = 16/210 (7%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDS 451
++ ++ + ++G+G + VY+ T AIK + T + + I +E+ +LS ++ S
Sbjct: 7 SSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQS 66
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
E I+++ S+ + +I+ ++C G++ ++ I++ I I+
Sbjct: 67 DV------ENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPISEPC------ISLIL 114
Query: 512 VEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPI-EDKSFENEGDRE 570
E AL+FIH + I+H D+K AN+L++ GN+KL DFG+A +L I K G
Sbjct: 115 RETLQALKFIHHA-GIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPY 173
Query: 571 YIAPEIIRDG-IYDFRADIFSLGLMMIEIA 599
++APE+IRDG Y+ ADI+SLG+ EIA
Sbjct: 174 WMAPEVIRDGQEYNVMADIWSLGITAYEIA 203
>7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 520
Score = 90.5 bits (223), Expect = 8e-18
Identities = 62/209 (29%), Positives = 112/209 (52%), Gaps = 20/209 (9%)
Query: 394 TKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR--ILQEINMLSTIQDS 451
T F + +G G ++TVY+ + +AIK V + + T+R ++ EI +L ++
Sbjct: 7 TDFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKH- 65
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
+YIV + + YI+ E+C GNL AFI+ ++ L + +
Sbjct: 66 --------KYIVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRT-----KKALPESTCRYFL 112
Query: 512 VEICLALRFIHDSCSIVHLDLKPANVLITFEGN---LKLADFGMATKLPIEDKSFENEGD 568
++ A++++ + + H DLKP N+L+T N LK+ADFG A L + + + + +G
Sbjct: 113 RQLAAAVQYMRAN-DVSHFDLKPQNLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGS 171
Query: 569 REYIAPEIIRDGIYDFRADIFSLGLMMIE 597
Y+APEI+R YD +AD++S+G+++ E
Sbjct: 172 PLYMAPEIVRKHQYDAKADLWSIGVILYE 200
>At5g28290 [R] KOG0589 Serine/threonine protein kinase
Length = 568
Score = 89.7 bits (221), Expect = 1e-17
Identities = 58/202 (28%), Positives = 106/202 (51%), Gaps = 16/202 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR--ILQEINMLSTIQDSVTNDTEGK 459
+GKG F + V Y +K +R + R QE+ ++S I++
Sbjct: 10 IGKGSFGSALLVRHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIRNP-------- 61
Query: 460 EYIVEFISSWSHKGSFY-IMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
+IVE+ SW KG + I+ +C+ G++ I++ A + ++ K +V++ +AL
Sbjct: 62 -FIVEYKDSWVEKGCYVCIVIGYCKGGDMAEAIKK---ANGVEFSEEKLCKWLVQLLMAL 117
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
++H S I+H D+K +N+ +T + +++L DFG+A L +D + G Y+ PE++
Sbjct: 118 EYLHAS-HILHRDVKCSNIFLTKDQDIRLGDFGLAKILTSDDLASSVVGTPSYMCPELLA 176
Query: 579 DGIYDFRADIFSLGLMMIEIAA 600
D Y ++DI+SLG M E+ A
Sbjct: 177 DIPYGSKSDIWSLGCCMYEMTA 198
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 89.0 bits (219), Expect = 2e-17
Identities = 72/277 (25%), Positives = 133/277 (47%), Gaps = 28/277 (10%)
Query: 327 HDQESSIFSP-SPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQRSINASIM 385
H + SP +P++ + TPT P ++K N+ + +++ + A +
Sbjct: 554 HTPQQVAQSPKAPAQETVTTPTSK-----PAQARSLSKELNEKKREERERRKKQLYAKLN 608
Query: 386 KN-PDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINM 444
+ D +TK++N+ +G+G VY T + AIK + K I+ EI +
Sbjct: 609 EICSDGDPSTKYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILV 668
Query: 445 LSTIQDSVTNDTEGKEY--IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRL 502
+ +G ++ IV FI S+ KG +++ E+ E G+L + ++ + Q
Sbjct: 669 M-----------KGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQ-- 715
Query: 503 EDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDK 561
I + E L F+H S ++H D+K N+L++ EG++KL DFG ++ + K
Sbjct: 716 ----IGAVCRETLSGLEFLH-SKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLK 770
Query: 562 SFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G ++APE++ Y + DI+SLG+M+IE+
Sbjct: 771 RTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEM 807
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 89.0 bits (219), Expect = 2e-17
Identities = 108/540 (20%), Positives = 204/540 (37%), Gaps = 44/540 (8%)
Query: 75 FYSEPLS-SRSNSNDTPLGLTRSVGVLNLSLETETPDVKDQKFNEENQSHIDSRVPQLQR 133
F PLS SR+ + LG + L+T DV+ + +S ++ V +
Sbjct: 62 FSGFPLSQSRTTVSRVSLGSRQHSSSSIRKLQTNVSDVRSYDERNQKKSAFENFVSSMSS 121
Query: 134 PLIXXXXXXXXXXXLKRTVSKTGFNISSPFSKNNAAYLKSWHSTNAATSSDLXXXXXXXX 193
L + ISSPF + ++ + T T
Sbjct: 122 FLTGGGSSPTSSYGSGSASPRKSTVISSPFDPKHVTHVGFNYDTGEFTGMPTEWQALLKV 181
Query: 194 XXXXXXEAKPDPVAFQSSGLISKMKQTILPKKLTIPDTPVKKSPLVSRHSDQELLDTPIL 253
E P A + + L + K P +++ LL L
Sbjct: 182 SGITKSEQVQHPQAVLDAMAFYSQSKKYLEEGA--------KPPFPRESTEKPLLSVSAL 233
Query: 254 EHSSIMSAQNQTTFPT-MYDSQLFKSPPMINTVLPXXXXXXXXXXXXXXXXXXKIVKNTE 312
SS + + T+ + +Y S+ +PP ++ P + +++
Sbjct: 234 SSSSHLQPTSATSSSSRLYPSRPAPTPPASSSSSPLLSSQTVKTTTSNASRQPSPLVSSK 293
Query: 313 LTSMLRQITDDLYGHDQESSIFSPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRND----P 368
T + + + Q S + N TP + + A+ T + + P
Sbjct: 294 STDNIIRSHSPVLLTPQTLSTSETKHIRPNNSTPYQRRAETSTKPKAVATPQKVEAPSAP 353
Query: 369 THLQPPEKQRSINASIM---------KNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETG 419
+ +Q+S +++++ KNP T + N +G+G VY T
Sbjct: 354 RLQKRAPRQQSNDSAVLAKLQSICNPKNP----TLLYRNFVKIGQGASGDVYSARQVGTN 409
Query: 420 LKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMT 479
L AIK + + I+ EI ++ + + IV FI ++ +K +++
Sbjct: 410 LSVAIKKMNINQQPKKEFIVNEILVMKS---------HHHKNIVNFIDTFFYKSELWMVM 460
Query: 480 EFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLI 539
E+ G+L + + +++ Q I I E L+ +H++ IVH D+K N+L+
Sbjct: 461 EYMRGGSLTEVVTNNTLSEGQ------IAAICKETLEGLQHLHEN-GIVHRDIKSDNILL 513
Query: 540 TFEGNLKLADFGMATKLPIE-DKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+ +G++KL DFG ++ K G ++APE++ Y F+ D++SLG+M IE+
Sbjct: 514 SLQGDIKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFKVDVWSLGIMAIEM 573
>CE16527 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kinase MKK4
Length = 359
Score = 89.0 bits (219), Expect = 2e-17
Identities = 70/231 (30%), Positives = 115/231 (49%), Gaps = 15/231 (6%)
Query: 378 RSINASIMKNPD-FHLT----TKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKH 432
RS++ I+K PD HL T ++S +G G + TV+++ E+G A+K +R
Sbjct: 41 RSMSTGILKFPDDAHLYPFNHTNLRHLSQVGAGYYGTVHKMQHNESGRLIAVKKIR---- 96
Query: 433 NFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQ 492
N I + +L + +E IV+F + +G +I E + ++D +
Sbjct: 97 --YNNICDQTRLLK--EHDTHMKSENVPNIVKFFGACFSEGDCWICMELMDI-SIDFLYK 151
Query: 493 EHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGM 552
K+ RL + I I V I AL ++ + +H D+KP+N+LI G++KL DFG+
Sbjct: 152 RVYSVKKSRLNENIIGHITVCIVDALDYLKRKLNRIHRDVKPSNILINAAGDVKLCDFGI 211
Query: 553 ATKLPIEDKSFENEGDREYIAPEIIRD-GIYDFRADIFSLGLMMIEIAANV 602
L G +Y+APE I + YD R+D++SLG+ + EIA V
Sbjct: 212 CGDLVGSYAITVEAGCVQYLAPERIENMDKYDIRSDVWSLGITLYEIATGV 262
>CE09940 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 468
Score = 88.6 bits (218), Expect = 3e-17
Identities = 65/236 (27%), Positives = 110/236 (46%), Gaps = 44/236 (18%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+GKG F V T T K+AIK + +K ++ D + Y
Sbjct: 112 LGKGSFGEVVAATCRSTSKKFAIKKIPFSK--------------------LSKDQYREAY 151
Query: 462 ----------IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
IV F +W K +I E C+ +L A+ H I LED +W +
Sbjct: 152 GHMNIPCHPNIVRFHQAWIDKQILHIQLEMCDK-SLAAYC--HGI---DWLEDKELWNVF 205
Query: 512 VEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIE------DKSFEN 565
++I L +H++ ++H D+KP N+ +T KL DFG+ + + E +K +++
Sbjct: 206 LDILQGLGHLHNNF-MLHNDIKPDNIFMTKNKVCKLGDFGLISDMRSEPINNSSNKHYQS 264
Query: 566 EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSD 621
EGD +Y + E I +G +DIFS G+ ++E+ N+ LP G+ W +R ++ +
Sbjct: 265 EGDGKYCSKEAI-NGTLSIFSDIFSFGISILEVGTNIHLPSYGTGWEPIRKWEIPE 319
>At3g04810 [R] KOG0589 Serine/threonine protein kinase
Length = 606
Score = 88.2 bits (217), Expect = 4e-17
Identities = 58/202 (28%), Positives = 104/202 (50%), Gaps = 16/202 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR--ILQEINMLSTIQDSVTNDTEGK 459
+GKG F + V Y +K +R + R QE+ ++S I +
Sbjct: 10 IGKGSFGSALLVRHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIHNP-------- 61
Query: 460 EYIVEFISSWSHKGSFY-IMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
+IVE+ SW KG + I+ +C+ G++ I++ + ++ K +V+I LAL
Sbjct: 62 -FIVEYKDSWVEKGCYVCIIIGYCKGGDMAEAIKK---TNGVHFTEEKLCKWLVQILLAL 117
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
++H + I+H D+K +N+ +T + +++L DFG+A L +D + G Y+ PE++
Sbjct: 118 EYLHAN-HILHRDVKCSNIFLTKDQDIRLGDFGLAKVLTSDDLASSVVGTPSYMCPELLA 176
Query: 579 DGIYDFRADIFSLGLMMIEIAA 600
D Y ++DI+SLG M E+ A
Sbjct: 177 DIPYGSKSDIWSLGCCMYEMTA 198
>Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kinase MKK4
Length = 399
Score = 87.8 bits (216), Expect = 5e-17
Identities = 82/326 (25%), Positives = 146/326 (44%), Gaps = 32/326 (9%)
Query: 326 GHDQESSIFSPSP------SKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQR- 378
G + SP+P S + K +F P L +PT +Q P +R
Sbjct: 17 GSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERL 76
Query: 379 ---SINAS--IMKNPDFH---LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT 430
SI +S + +P+ H ++ +G+G + +V ++ +G A+K +R T
Sbjct: 77 RTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRST 136
Query: 431 -KHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDA 489
++L +++++ D YIV+F + +G +I E + D
Sbjct: 137 VDEKEQKQLLMDLDVVMRSSDC--------PYIVQFYGALFREGDCWICMELMST-SFDK 187
Query: 490 FIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLAD 549
F + + + + KI + AL + ++ I+H D+KP+N+L+ GN+KL D
Sbjct: 188 FYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCD 247
Query: 550 FGMATKLPIEDKSFENEGDREYIAPEII-----RDGIYDFRADIFSLGLMMIEIAANVI- 603
FG++ +L + G R Y+APE I R G YD R+D++SLG+ + E+A
Sbjct: 248 FGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQG-YDVRSDVWSLGITLYELATGRFP 306
Query: 604 LPDNGSAWHKLRSGDLSDAGRLSSAE 629
P S + +L D +LS++E
Sbjct: 307 YPKWNSVFDQLTQVVKGDPPQLSNSE 332
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 87.8 bits (216), Expect = 5e-17
Identities = 65/207 (31%), Positives = 106/207 (50%), Gaps = 20/207 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK-HNFTNRILQEINMLSTIQDSVTN 454
F+ +G+G F VY+ TG AIK + + + I QEI +LS
Sbjct: 34 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDS---- 89
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGN-LDAFIQEHVIAKQQRLEDWRIWKIIVE 513
+Y+ ++ S+ +I+ E+ G+ LD + K +L++ I I+ E
Sbjct: 90 -----QYVTKYFGSFLKGSKLWIIMEYLGGGSALD-------LTKSGKLDESHIAVILRE 137
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP-IEDKSFENEGDREYI 572
I L ++H I H D+K ANVL++ G++K+ADFG+A +L K G ++
Sbjct: 138 ILKGLEYLHSERKI-HRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWM 196
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEIA 599
APE+I+ YD++ADI+SLG+ IE+A
Sbjct: 197 APELIKQSSYDYKADIWSLGITAIELA 223
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 87.0 bits (214), Expect = 9e-17
Identities = 65/225 (28%), Positives = 114/225 (49%), Gaps = 19/225 (8%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK-HNFTNRILQEINMLSTIQDS 451
TTK+ ++ +GKG + +VY+ +T A+K + T+ I EI ML
Sbjct: 246 TTKYEFLNELGKGSYGSVYKARDLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHP 305
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
+V ++ S+ + +I+ E+C G+ + + + ++ LE+++I I
Sbjct: 306 ---------NVVRYLGSYQGEDYLWIVMEYCGGGS----VADLMNVTEEALEEYQIAYIC 352
Query: 512 VEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP-IEDKSFENEGDRE 570
E L ++H S VH D+K N+L+T +G +KL DFG+A +L K G
Sbjct: 353 REALKGLAYLH-SIYKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPH 411
Query: 571 YIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLR 615
++APE+I++ YD + D+++LG+ IE+A LP S H +R
Sbjct: 412 WMAPEVIQENRYDGKVDVWALGVSAIEMAEG--LPPRSSV-HPMR 453
>At1g54510 [R] KOG0589 Serine/threonine protein kinase
Length = 612
Score = 87.0 bits (214), Expect = 9e-17
Identities = 55/201 (27%), Positives = 105/201 (51%), Gaps = 16/201 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR--ILQEINMLSTIQDSVTNDTEGK 459
+GKG F + V KY +K +R + R QE+ ++S ++
Sbjct: 10 IGKGSFGSALLVRHKHEKKKYVLKKIRLARQTQRTRRSAHQEMELISKMRHP-------- 61
Query: 460 EYIVEFISSWSHKGSFY-IMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
+IVE+ SW K + I+ +CE G++ I++ + ++ ++ K +V++ + L
Sbjct: 62 -FIVEYKDSWVEKACYVCIVIGYCEGGDMAQAIKK---SNGVHFQEEKLCKWLVQLLMGL 117
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
++H + I+H D+K +N+ +T E +++L DFG+A L +D + G Y+ PE++
Sbjct: 118 EYLHSN-HILHRDVKCSNIFLTKEQDIRLGDFGLAKILTSDDLTSSVVGTPSYMCPELLA 176
Query: 579 DGIYDFRADIFSLGLMMIEIA 599
D Y ++DI+SLG + E+A
Sbjct: 177 DIPYGSKSDIWSLGCCIYEMA 197
>HsM5454174 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 86.7 bits (213), Expect = 1e-16
Identities = 70/209 (33%), Positives = 107/209 (50%), Gaps = 24/209 (11%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK-HNFTNRILQEINMLSTIQDSVTN 454
F+ + +GKG F VY+ T AIK + + + I QEI +LS
Sbjct: 20 FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP--- 76
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGN-LDAFIQEHVIAKQQRLEDWRIWKIIVE 513
YI + S+ +I+ E+ G+ LD + K LE+ I I+ E
Sbjct: 77 ------YITRYFGSYLKSTKLWIIMEYLGGGSALD-------LLKPGPLEETYIATILRE 123
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP---IEDKSFENEGDRE 570
I L ++H I H D+K ANVL++ +G++KLADFG+A +L I+ +F G
Sbjct: 124 ILKGLDYLHSERKI-HRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV--GTPF 180
Query: 571 YIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
++APE+I+ YDF+ADI+SLG+ IE+A
Sbjct: 181 WMAPEVIKQSAYDFKADIWSLGITAIELA 209
>Hs21361358 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 86.7 bits (213), Expect = 1e-16
Identities = 70/209 (33%), Positives = 107/209 (50%), Gaps = 24/209 (11%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK-HNFTNRILQEINMLSTIQDSVTN 454
F+ + +GKG F VY+ T AIK + + + I QEI +LS
Sbjct: 20 FTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP--- 76
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGN-LDAFIQEHVIAKQQRLEDWRIWKIIVE 513
YI + S+ +I+ E+ G+ LD + K LE+ I I+ E
Sbjct: 77 ------YITRYFGSYLKSTKLWIIMEYLGGGSALD-------LLKPGPLEETYIATILRE 123
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP---IEDKSFENEGDRE 570
I L ++H I H D+K ANVL++ +G++KLADFG+A +L I+ +F G
Sbjct: 124 ILKGLDYLHSERKI-HRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV--GTPF 180
Query: 571 YIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
++APE+I+ YDF+ADI+SLG+ IE+A
Sbjct: 181 WMAPEVIKQSAYDFKADIWSLGITAIELA 209
>Hs14589902 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 278
Score = 86.7 bits (213), Expect = 1e-16
Identities = 61/203 (30%), Positives = 105/203 (51%), Gaps = 15/203 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQEINMLSTIQDSVTNDTEGKE 460
+G+G + V ++ +G A+K +R T ++ R+L ++++ D
Sbjct: 3 LGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC--------P 54
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
+ V F + +G +I E + +LD F ++ VI K Q + + + KI V I AL
Sbjct: 55 FTVTFYGALFREGDMWICMELMDT-SLDKFYKQ-VIDKGQTIPEDILGKIAVSIVKALEH 112
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG 580
+H S++H D+KP+NVLI G +K+ DFG++ L + G + Y+APE I
Sbjct: 113 LHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPE 172
Query: 581 I----YDFRADIFSLGLMMIEIA 599
+ Y ++DI+SLG+ MIE+A
Sbjct: 173 LNQKGYSVKSDIWSLGITMIELA 195
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 86.7 bits (213), Expect = 1e-16
Identities = 56/216 (25%), Positives = 110/216 (50%), Gaps = 14/216 (6%)
Query: 389 DFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTI 448
D TK+ ++G+G ++ Y E+G +YA+K VR K + ++ +++ I
Sbjct: 33 DLEYHTKYMLKKLLGRGAYAQCYLAEI-ESGEQYAMKVVR-LKDIKSRKVHEKLESEIAI 90
Query: 449 QDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIW 508
+ N +V+ S+ +++ E CE G LDA ++ + +L++ +
Sbjct: 91 HSKLDNPN-----VVKMYRSFRSSEYVFMVLELCERGALDALLK-----RNGKLKERHVA 140
Query: 509 KIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGD 568
+ + + L ++H+S S+VH DLK N+ + + N+K+ DFG++ + +K G
Sbjct: 141 RFVKQTVEGLIYLHNSVSVVHRDLKLGNLFLDSKFNVKIGDFGLSAVIKDGEKKVTMCGT 200
Query: 569 REYIAPEII--RDGIYDFRADIFSLGLMMIEIAANV 602
YIAPE++ + + F ADI+SLG+++ + V
Sbjct: 201 PNYIAPEVLFGKASGHSFEADIWSLGVIIYTLLVGV 236
>At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 356
Score = 86.7 bits (213), Expect = 1e-16
Identities = 56/226 (24%), Positives = 113/226 (49%), Gaps = 16/226 (7%)
Query: 377 QRSINASIMKNPDFHLTTK-FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT-KHNF 434
++ S K DF +T + V ++GKG V V G +A+K ++ +
Sbjct: 50 EKQSRQSDSKELDFEITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEI 109
Query: 435 TNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEH 494
+I+QE+ + + ++V S+ H G+F ++ E+ + G+L
Sbjct: 110 RKQIVQELK--------INQASSQCPHVVVCYHSFYHNGAFSLVLEYMDRGSL-----AD 156
Query: 495 VIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMAT 554
VI + + + + + + ++ L L ++H+ ++H D+KP+N+L+ +G +K++DFG++
Sbjct: 157 VIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVSA 216
Query: 555 KLPIEDKSFEN-EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
L + G Y++PE I YD+ +DI+SLG+ ++E A
Sbjct: 217 SLASSMGQRDTFVGTYNYMSPERISGSTYDYSSDIWSLGMSVLECA 262
>Hs14589900 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 334
Score = 86.3 bits (212), Expect = 2e-16
Identities = 61/203 (30%), Positives = 105/203 (51%), Gaps = 15/203 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQEINMLSTIQDSVTNDTEGKE 460
+G+G + V ++ +G A+K +R T ++ R+L ++++ D
Sbjct: 59 LGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC--------P 110
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
+ V F + +G +I E + +LD F ++ VI K Q + + + KI V I AL
Sbjct: 111 FTVTFYGALFREGDVWICMELMDT-SLDKFYKQ-VIDKGQTIPEDILGKIAVSIVKALEH 168
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG 580
+H S++H D+KP+NVLI G +K+ DFG++ L + G + Y+APE I
Sbjct: 169 LHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPE 228
Query: 581 I----YDFRADIFSLGLMMIEIA 599
+ Y ++DI+SLG+ MIE+A
Sbjct: 229 LNQKGYSVKSDIWSLGITMIELA 251
>At1g02970 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 500
Score = 86.3 bits (212), Expect = 2e-16
Identities = 87/302 (28%), Positives = 130/302 (42%), Gaps = 62/302 (20%)
Query: 394 TKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVT 453
T F + +G G FS V++V G YA+ KH+ L + ++
Sbjct: 247 TDFHEIRQIGAGHFSRVFKVLKRMDGCLYAV------KHSTRKLYLDSERRKAMMEVQAL 300
Query: 454 NDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVE 513
E IV + SSW YI E C++ +L A ++ + +R I I+ +
Sbjct: 301 AALGFHENIVGYYSSWFENEQLYIQLELCDH-SLSALPKKSSLKVSER----EILVIMHQ 355
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFE-NEGDREYI 572
I AL F+H+ I HLD+KP N+ I G KL DFG AT+L DKS EGD Y+
Sbjct: 356 IAKALHFVHEK-GIAHLDVKPDNIYIK-NGVCKLGDFGCATRL---DKSLPVEEGDARYM 410
Query: 573 APEIIRDGIYDF-RADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSSAEIH 631
EI+ + + DIFSLG+ + E+ I
Sbjct: 411 PQEILNEDYEHLDKVDIFSLGVTVYEL-------------------------------IK 439
Query: 632 SSSLFSNKKDHTNITDITTHETKIPAWVPKFLLDG--ISLERTIRWMIEPDYRDRPSASD 689
S L ++ NI E K+P LL G + L++ ++ M++ D + RPSA +
Sbjct: 440 GSPLTESRNQSLNI-----KEGKLP------LLPGHSLQLQQLLKTMMDRDPKRRPSARE 488
Query: 690 LL 691
LL
Sbjct: 489 LL 490
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 86.3 bits (212), Expect = 2e-16
Identities = 61/236 (25%), Positives = 120/236 (50%), Gaps = 18/236 (7%)
Query: 367 DPTHLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVY---QVTFPETGLKYA 423
D L E + + I + D ++F + ++G+G F V+ ++ + G YA
Sbjct: 170 DTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYA 229
Query: 424 IKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCE 483
+K ++ +R+ ST + + D G +IV ++ G Y++ +F
Sbjct: 230 MKVLKKATLKVKDRVR------STNERKILADV-GHAFIVRLHYAFQTPGKLYLILDFLR 282
Query: 484 NGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEG 543
G+L + + V+ ++ ++ + + E+ LA+ +H + I++ DLKP N+L+ G
Sbjct: 283 GGDLFTRLSKEVMFTEEDVKFY-----LAELALAMNHLH-TLGIIYRDLKPENILLDEHG 336
Query: 544 NLKLADFGMATKLPIE-DKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
++ L DFG++ K P++ K++ G EY+APEI+ +DF AD +S G++M E+
Sbjct: 337 HIALTDFGLS-KQPLDGSKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEM 391
Score = 53.1 bits (126), Expect = 1e-06
Identities = 39/139 (28%), Positives = 68/139 (48%), Gaps = 11/139 (7%)
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
IV S + GS Y++ E + G L + ++A Q E ++ I A+ ++
Sbjct: 631 IVTLYSVYEDAGSAYLVMELLKGGEL----LDRILAVGQMCES-EASAVLRTIASAVAYL 685
Query: 522 HDSCSIVHLDLKPANVLITF----EGNLKLADFGMATKLPIEDKSFENEG-DREYIAPEI 576
H+ +VH DLKP+N++ LKL D G A +L ++ ++APE+
Sbjct: 686 HEH-GVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEV 744
Query: 577 IRDGIYDFRADIFSLGLMM 595
++ YD DI+SLG+++
Sbjct: 745 LKRQGYDLACDIWSLGVLL 763
>CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 706
Score = 85.9 bits (211), Expect = 2e-16
Identities = 64/204 (31%), Positives = 103/204 (50%), Gaps = 22/204 (10%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
+S++ +GKG F VY E G K AIK + K NR+ EI + ++ S
Sbjct: 13 YSHLKEIGKGGFGVVYAAQ-RENGEKVAIKRI--DKKVPKNRVWTEIQTMKELKKS---- 65
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+Y+VEF + G YI+ E CE G+L A+++EH L+D ++ ++
Sbjct: 66 ----KYVVEFYEDFVEDGYTYIVMELCEGGSLQAYVREH-----GALDDATAVHVLRQLI 116
Query: 516 LALRFIHDSCSIVHLDLKPANVLI----TFEGNLKLADFGMATKLPIEDKSFENEGDREY 571
A+ F+H +++H DL NV I + +KL DFG+AT L + + G +
Sbjct: 117 SAVSFMH-RVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATTLGRGETTCTIVGTPGF 175
Query: 572 IAPEIIRDGIYDFRADIFSLGLMM 595
IAP++ D Y AD++SLG ++
Sbjct: 176 IAPQVY-DQEYTQSADVYSLGAVL 198
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 85.9 bits (211), Expect = 2e-16
Identities = 66/207 (31%), Positives = 106/207 (50%), Gaps = 14/207 (6%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F ++++G+G ++ V Q T YAIK ++ N ++I+ + T + SV
Sbjct: 253 FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNED----EDIDWVQT-EKSVFEA 307
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++V S + + + + EF G+L +Q+ Q++L + EI
Sbjct: 308 ASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQ-----QRKLPEEHARFYSGEII 362
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYIA 573
LAL F+H S I++ DLK NVLI EG++KL D+GM K I+D + G YIA
Sbjct: 363 LALHFLH-SRGIIYRDLKLDNVLIDAEGHIKLTDYGMC-KENIKDGDLTSTFCGTPNYIA 420
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEIAA 600
PEI+R Y F D ++LG++M E+ A
Sbjct: 421 PEILRGDEYGFSVDWWALGVLMFEMMA 447
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/206 (29%), Positives = 112/206 (54%), Gaps = 19/206 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V +G+G + +V++ E+G AIK V P + I++EI+++ +
Sbjct: 63 FDIVGKLGEGSYGSVHKAIHRESGHVLAIKKV-PVDTDL-QEIIKEISIMQQCKS----- 115
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+Y+V++ S+ +I+ E+C G++ ++ A+++ L + I ++ +
Sbjct: 116 ----KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMR----ARRKPLSEQEISAVLRDTL 167
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYIA 573
L+++HD I H D+K N+L+ +G KLADFG+A +L + + N G ++A
Sbjct: 168 KGLQYLHDLKKI-HRDIKAGNILLNTDGIAKLADFGVAGQL-TDTMAKRNTVIGTPFWMA 225
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEIA 599
PE+I + YD +ADI+SLG+ IE+A
Sbjct: 226 PEVIEEIGYDTKADIWSLGITAIEMA 251
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/206 (29%), Positives = 112/206 (54%), Gaps = 19/206 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V +G+G + +V++ E+G AIK V P + I++EI+++ +
Sbjct: 35 FDIVGKLGEGSYGSVHKAIHRESGHVLAIKKV-PVDTDL-QEIIKEISIMQQCKS----- 87
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+Y+V++ S+ +I+ E+C G++ ++ A+++ L + I ++ +
Sbjct: 88 ----KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMR----ARRKPLSEQEISAVLRDTL 139
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYIA 573
L+++HD I H D+K N+L+ +G KLADFG+A +L + + N G ++A
Sbjct: 140 KGLQYLHDLKKI-HRDIKAGNILLNTDGIAKLADFGVAGQL-TDTMAKRNTVIGTPFWMA 197
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEIA 599
PE+I + YD +ADI+SLG+ IE+A
Sbjct: 198 PEVIEEIGYDTKADIWSLGITAIEMA 223
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/206 (29%), Positives = 112/206 (54%), Gaps = 19/206 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V +G+G + +V++ E+G AIK V P + I++EI+++ +
Sbjct: 35 FDIVGKLGEGSYGSVHKAIHRESGHVLAIKKV-PVDTDL-QEIIKEISIMQQCKS----- 87
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+Y+V++ S+ +I+ E+C G++ ++ A+++ L + I ++ +
Sbjct: 88 ----KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMR----ARRKPLSEQEISAVLRDTL 139
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYIA 573
L+++HD I H D+K N+L+ +G KLADFG+A +L + + N G ++A
Sbjct: 140 KGLQYLHDLKKI-HRDIKAGNILLNTDGIAKLADFGVAGQL-TDTMAKRNTVIGTPFWMA 197
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEIA 599
PE+I + YD +ADI+SLG+ IE+A
Sbjct: 198 PEVIEEIGYDTKADIWSLGITAIEMA 223
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/206 (29%), Positives = 112/206 (54%), Gaps = 19/206 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V +G+G + +V++ E+G AIK V P + I++EI+++ +
Sbjct: 63 FDIVGKLGEGSYGSVHKAIHRESGHVLAIKKV-PVDTDL-QEIIKEISIMQQCKS----- 115
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+Y+V++ S+ +I+ E+C G++ ++ A+++ L + I ++ +
Sbjct: 116 ----KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMR----ARRKPLSEQEISAVLRDTL 167
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYIA 573
L+++HD I H D+K N+L+ +G KLADFG+A +L + + N G ++A
Sbjct: 168 KGLQYLHDLKKI-HRDIKAGNILLNTDGIAKLADFGVAGQL-TDTMAKRNTVIGTPFWMA 225
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEIA 599
PE+I + YD +ADI+SLG+ IE+A
Sbjct: 226 PEVIEEIGYDTKADIWSLGITAIEMA 251
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 85.5 bits (210), Expect = 3e-16
Identities = 61/227 (26%), Positives = 111/227 (48%), Gaps = 18/227 (7%)
Query: 375 EKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT---K 431
+ ++++ ++K F + ++GKG F VYQV ET YA+K +R +
Sbjct: 113 DNEKALEGDLVKVSGVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIME 172
Query: 432 HNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFI 491
N + E ++L+ I +IV+ S+ K Y++ +F G+L +
Sbjct: 173 KNHAEYMKAERDILTKIDHP---------FIVQLKYSFQTKYRLYLVLDFINGGHLFFQL 223
Query: 492 QEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFG 551
+ ++ + EI A+ +H+ I+H DLKP N+L+ +G++ L DFG
Sbjct: 224 YHQGLFREDLARVYT-----AEIVSAVSHLHEK-GIMHRDLKPENILMDTDGHVMLTDFG 277
Query: 552 MATKLPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+A + +S G EY+APEI+R +D AD +S+G+++ E+
Sbjct: 278 LAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEM 324
>7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 396
Score = 85.5 bits (210), Expect = 3e-16
Identities = 58/226 (25%), Positives = 114/226 (49%), Gaps = 18/226 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G G V +V T L A K + K +IL+E+ +L
Sbjct: 93 LGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFP--------- 143
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
+IV F ++ G I E+ + G+LD ++ + R+ + + +I + + L +
Sbjct: 144 HIVGFYGAFYSDGEISICMEYMDGGSLDL-----ILKRAGRIPESILGRITLAVLKGLSY 198
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG 580
+ D+ +I+H D+KP+N+L+ G +K+ DFG++ +L I+ + G R Y++PE ++
Sbjct: 199 LRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQL-IDSMANSFVGTRSYMSPERLQGT 257
Query: 581 IYDFRADIFSLGLMMIEIAANV--ILPDNGSAWHKLRSGDLSDAGR 624
Y ++DI+SLGL ++E+A + I P N + + + + ++G+
Sbjct: 258 HYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQ 303
>YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 515
Score = 85.1 bits (209), Expect = 3e-16
Identities = 78/292 (26%), Positives = 139/292 (46%), Gaps = 36/292 (12%)
Query: 328 DQESSIFSPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPP-EKQRSINASIMK 386
D S+ F SPS TN TP+ G ++A T + N+ + PP E+ S A+ +K
Sbjct: 121 DAYSNNFGLSPSSTN-STPSTIQ---GLSNIA--TPVENEHSISLPPLEESLSPAAADLK 174
Query: 387 -------NPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFT--NR 437
N ++ + +G G TV + A K++ ++N T N+
Sbjct: 175 DTLSGTSNGNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQ 234
Query: 438 ILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHK---GSFYIMTEFCENGNLDAFIQEH 494
+++E+ S+ + + E I+ F ++ ++ I+ E+ + G+LD + +
Sbjct: 235 LVREL--------SIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVY 286
Query: 495 --------VIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLK 546
V +K+ + I KI + L ++ I+H D+KP+NVLI +G +K
Sbjct: 287 KRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIK 346
Query: 547 LADFGMATKLPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
L DFG++ KL I + G Y++PE I+ +Y + D++SLGLM+IE+
Sbjct: 347 LCDFGVSKKL-INSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIEL 397
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 85.1 bits (209), Expect = 3e-16
Identities = 91/333 (27%), Positives = 150/333 (44%), Gaps = 60/333 (18%)
Query: 345 TPTKTSF-DIGPDSLAIMTKLRNDPTHLQPPEKQRS------------INASIMKNPDF- 390
+P TSF D+ ++L+I + + E +R+ ++ S+ +N DF
Sbjct: 965 SPRLTSFGDVEEEALSIQLLQKETMLRIDELEIERNNTLLERLAIGHVLDDSVFRNRDFI 1024
Query: 391 HLTTKFSNVSI-------MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEIN 443
L + FSN++I + G F VY ETG A+K ++ + +I+
Sbjct: 1025 KLASSFSNITIRWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIH 1084
Query: 444 MLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLE 503
T+ + + + Y VE H+ YI EFC+ G+L + R+E
Sbjct: 1085 NEMTVLERLNHPNVVTYYGVEV-----HREKVYIFMEFCQGGSLADLLAHG------RIE 1133
Query: 504 DWRIWKI-IVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDK 561
D + K+ +V++ L +IH S I+H D+KPAN+L+ G +K +DFG A + P D
Sbjct: 1134 DENVLKVYVVQLLEGLAYIH-SQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDP 1192
Query: 562 SFENE----------GDREYIAPEII---RDGIYDFRA-DIFSLGLMMIEIAANVILPDN 607
E G Y+APEII + G DF A DI+SLG +++E+
Sbjct: 1193 EVRYEDIQPELQHLAGTPMYMAPEIILGTKKG--DFGAMDIWSLGCVILEMMT------G 1244
Query: 608 GSAWHKLRSGDLSDAGRLSSAEIHSSSLFSNKK 640
+ W ++ D A A +H+ S+ N+K
Sbjct: 1245 STPWSEM---DNEWAIMYHVAAMHTPSIPQNEK 1274
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 85.1 bits (209), Expect = 3e-16
Identities = 57/227 (25%), Positives = 119/227 (52%), Gaps = 17/227 (7%)
Query: 376 KQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVY---QVTFPETGLKYAIKSVRPTKH 432
K+ SI + + + F + ++G+G F V+ +VT P++G YA+K ++
Sbjct: 42 KEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATL 101
Query: 433 NFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQ 492
+R+ ++ + + D ++V+ ++ +G Y++ +F G+L +
Sbjct: 102 KVRDRVRTKM------ERDILADVN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLS 154
Query: 493 EHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGM 552
+ V+ ++ ++ + + E+ L L +H S I++ DLKP N+L+ EG++KL DFG+
Sbjct: 155 KEVMFTEEDVKFY-----LAELALGLDHLH-SLGIIYRDLKPENILLDEEGHIKLTDFGL 208
Query: 553 ATK-LPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+ + + E K++ G EY+APE++ + AD +S G++M E+
Sbjct: 209 SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEM 255
Score = 55.1 bits (131), Expect = 4e-07
Identities = 53/212 (25%), Positives = 94/212 (44%), Gaps = 23/212 (10%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+G G +S + T ++YA+K + +K + + +EI +L
Sbjct: 424 IGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPS----EEIEILLRYGQHPN-------- 471
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
I+ + Y++TE G L I +Q+ + ++ I + ++
Sbjct: 472 IITLKDVYDDGKHVYLVTELMRGGEL-----LDKILRQKFFSEREASFVLHTIGKTVEYL 526
Query: 522 HDSCSIVHLDLKPANVLITFE-GN---LKLADFGMATKLPIEDKSFENEG-DREYIAPEI 576
H S +VH DLKP+N+L E GN L++ DFG A +L E+ ++APE+
Sbjct: 527 H-SQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEV 585
Query: 577 IRDGIYDFRADIFSLGLMMIEIAANVILPDNG 608
++ YD DI+SLG+++ + A NG
Sbjct: 586 LKRQGYDEGCDIWSLGILLYTMLAGYTPFANG 617
>At1g66910 [T] KOG1187 Serine/threonine protein kinase
Length = 655
Score = 84.7 bits (208), Expect = 4e-16
Identities = 72/249 (28%), Positives = 124/249 (48%), Gaps = 29/249 (11%)
Query: 363 KLRNDPT-HLQPPEKQRSINASI-MKNPDFHLTTKFSN--VSIMGKGQFSTVYQVTFPET 418
K NDP +Q+++ A I +K+ + T + ++GKG F TVY+ T +
Sbjct: 300 KTLNDPRMRTSDDSRQQNLKALIPLKHYSYAQVTSITKSFAEVIGKGGFGTVYRGTLYD- 358
Query: 419 GLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIM 478
G A+K ++ ++ N + I + +M T ++ ++ F S + Y
Sbjct: 359 GRSVAVKVLKESQGNGEDFINEVASMSQTSHVNIVT-------LLGFCSEGYKRAIIY-- 409
Query: 479 TEFCENGNLDAFIQEHVIAKQQRLEDWR-IWKIIVEICLALRFIHDSCS--IVHLDLKPA 535
EF ENG+LD FI +K+ DWR ++ I + + L ++H C IVH D+KP
Sbjct: 410 -EFMENGSLDKFIS----SKKSSTMDWRELYGIALGVARGLEYLHHGCRTRIVHFDIKPQ 464
Query: 536 NVLITFEGNLKLADFGMATKLPIEDKS----FENEGDREYIAPEIIRD--GIYDFRADIF 589
NVL+ + K++DFG+A KL +S + G YIAPE+ G ++D++
Sbjct: 465 NVLLDDNLSPKVSDFGLA-KLCERKESILSLMDTRGTIGYIAPEVFSRVYGRVSHKSDVY 523
Query: 590 SLGLMMIEI 598
S G+++++I
Sbjct: 524 SYGMLVLDI 532
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 84.3 bits (207), Expect = 6e-16
Identities = 65/239 (27%), Positives = 119/239 (49%), Gaps = 25/239 (10%)
Query: 366 NDPTHLQPPEKQRSINASIMKNPDFHLTTK---FSNVSIMGKGQFSTVYQVTFPETGLKY 422
ND H +K+R +++ K P + T+ + +G+G F+ +Q+ ++G +
Sbjct: 49 NDHHHQPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQIK-DDSGEIF 107
Query: 423 AIKSVRPTK---HNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMT 479
A K+V ++L EI I S+++ IV+FI + + YI+
Sbjct: 108 AAKTVAKASIKSEKTRKKLLSEIQ----IHKSMSHPN-----IVQFIDCFEDDSNVYILL 158
Query: 480 EFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLI 539
E C NG+L ++ +++ L + + +IC A++++H S ++H DLK N+
Sbjct: 159 EICPNGSL-----MELLKRRKVLTEPEVRFFTTQICGAIKYMH-SRRVIHRDLKLGNIFF 212
Query: 540 TFEGNLKLADFGMATKLPIE-DKSFENEGDREYIAPEII--RDGIYDFRADIFSLGLMM 595
NLK+ DFG+A L E ++ + G YIAPE++ + + F DI+SLG+M+
Sbjct: 213 DSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVML 271
>SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 84.3 bits (207), Expect = 6e-16
Identities = 68/230 (29%), Positives = 116/230 (49%), Gaps = 21/230 (9%)
Query: 389 DFHLTTKFSNVSIM-----GKGQFSTVYQVTFPETGLKYAIKSVRPTKHN-FTNRILQEI 442
D HL +N I+ G+G +V + T + +A+K+V + ++L+E+
Sbjct: 67 DDHLHELVTNGGILYMNSLGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLREL 126
Query: 443 NMLSTIQDSVTNDTEGKEYIVEFISSWSHKGS--FYIMTEFCENGNLDAFIQEHVIAKQQ 500
+ N + YIV++ + + I E+C G+LDA I + V ++
Sbjct: 127 KI---------NRSCTSPYIVKYYGACYNNAECQLNIAMEYCGAGSLDA-IYKRVRSQGG 176
Query: 501 RLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIED 560
R + + KI + L ++HD I+H D+KP+N+L+T +G +KL DFG++ +L +
Sbjct: 177 RTGERPLGKIAFGVLSGLSYLHDR-KIIHRDIKPSNILLTSKGQVKLCDFGVSGEL-VNS 234
Query: 561 KSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVI-LPDNGS 609
+ G Y+APE I G Y +DI+SLGL ++E+A N P GS
Sbjct: 235 LAGTFTGTSYYMAPERISGGSYTISSDIWSLGLTLMEVALNRFPFPPEGS 284
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 84.3 bits (207), Expect = 6e-16
Identities = 63/221 (28%), Positives = 103/221 (46%), Gaps = 35/221 (15%)
Query: 392 LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR--PTKHNFTNRILQEINMLSTIQ 449
+T K+ + +G+GQ+ VY +TG A+K +R P H E+ + I+
Sbjct: 1289 VTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIK 1348
Query: 450 DSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAF----IQEHVIAKQQRLEDW 505
+V + H+ YI E+C+ G L+ +QEHVI +
Sbjct: 1349 HP---------NLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYSK---- 1395
Query: 506 RIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN 565
+I +A+ +H+ IVH D+K AN+ +T G +KL DFG + KL ++
Sbjct: 1396 -------QITIAINVLHEH-GIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPG 1447
Query: 566 E-----GDREYIAPEII---RDGIYDFRADIFSLGLMMIEI 598
E G Y+APE+I + + ADI+SLG ++IE+
Sbjct: 1448 EVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEM 1488
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 84.3 bits (207), Expect = 6e-16
Identities = 63/221 (28%), Positives = 103/221 (46%), Gaps = 35/221 (15%)
Query: 392 LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR--PTKHNFTNRILQEINMLSTIQ 449
+T K+ + +G+GQ+ VY +TG A+K +R P H E+ + I+
Sbjct: 1338 VTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIK 1397
Query: 450 DSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAF----IQEHVIAKQQRLEDW 505
+V + H+ YI E+C+ G L+ +QEHVI +
Sbjct: 1398 HP---------NLVRYFGVELHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYSK---- 1444
Query: 506 RIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN 565
+I +A+ +H+ IVH D+K AN+ +T G +KL DFG + KL ++
Sbjct: 1445 -------QITIAINVLHEH-GIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPG 1496
Query: 566 E-----GDREYIAPEII---RDGIYDFRADIFSLGLMMIEI 598
E G Y+APE+I + + ADI+SLG ++IE+
Sbjct: 1497 EVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEM 1537
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 84.3 bits (207), Expect = 6e-16
Identities = 59/210 (28%), Positives = 112/210 (53%), Gaps = 21/210 (10%)
Query: 395 KFSNVSIMGKGQFSTVY---QVTFPETGLKYAIKSVRPT--KHNFTNRILQEINMLSTIQ 449
+F + ++G+G F V+ +V ++G YA+K ++ K R E N+L+ I
Sbjct: 103 QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHIS 162
Query: 450 DSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWK 509
+IV+ ++ +G Y++ +F G+L + + V+ + ++ +
Sbjct: 163 HP---------FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFY---- 209
Query: 510 IIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGD 568
+ E+ LAL +H S IV+ DLKP N+L+ +G++K+ DFG++ + + E K++ G
Sbjct: 210 -LAELTLALEHLH-SLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGT 267
Query: 569 REYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
EY+APE+I + AD +SLG++M E+
Sbjct: 268 VEYMAPEVINRRGHSMAADFWSLGVLMFEM 297
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/208 (23%), Positives = 99/208 (47%), Gaps = 22/208 (10%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T + + +G G S V++ T KYA+K V+ + T +E+++L
Sbjct: 451 TDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT----EEVDILLRHSHH- 505
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+++V+ + + + Y++ E CE G L + ++ K+ + + I+
Sbjct: 506 -------QFVVKLFDVYEDETAIYMIEELCEGGEL----LDKLVNKKSLGSEKEVAAIMA 554
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFE----GNLKLADFGMATKLPIEDKSFENEG- 567
+ A++++H S + H DL AN+L + +L++ DFG A + E+
Sbjct: 555 NLLNAVQYLH-SQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY 613
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMM 595
+++APE++R YD D++SLG+++
Sbjct: 614 TAQFVAPEVLRKQGYDRSCDVWSLGVLL 641
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 84.3 bits (207), Expect = 6e-16
Identities = 59/210 (28%), Positives = 112/210 (53%), Gaps = 21/210 (10%)
Query: 395 KFSNVSIMGKGQFSTVY---QVTFPETGLKYAIKSVRPT--KHNFTNRILQEINMLSTIQ 449
+F + ++G+G F V+ +V ++G YA+K ++ K R E N+L+ I
Sbjct: 46 QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHIS 105
Query: 450 DSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWK 509
+IV+ ++ +G Y++ +F G+L + + V+ + ++ +
Sbjct: 106 HP---------FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFY---- 152
Query: 510 IIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGD 568
+ E+ LAL +H S IV+ DLKP N+L+ +G++K+ DFG++ + + E K++ G
Sbjct: 153 -LAELTLALEHLH-SLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGT 210
Query: 569 REYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
EY+APE+I + AD +SLG++M E+
Sbjct: 211 VEYMAPEVINRRGHSMAADFWSLGVLMFEM 240
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/208 (23%), Positives = 99/208 (47%), Gaps = 22/208 (10%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T + + +G G S V++ T KYA+K V+ + T +E+++L
Sbjct: 394 TDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT----EEVDILLRHSHH- 448
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+++V+ + + + Y++ E CE G L + ++ K+ + + I+
Sbjct: 449 -------QFVVKLFDVYEDETAIYMIEELCEGGEL----LDKLVNKKSLGSEKEVAAIMA 497
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFE----GNLKLADFGMATKLPIEDKSFENEG- 567
+ A++++H S + H DL AN+L + +L++ DFG A + E+
Sbjct: 498 NLLNAVQYLH-SQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY 556
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMM 595
+++APE++R YD D++SLG+++
Sbjct: 557 TAQFVAPEVLRKQGYDRSCDVWSLGVLL 584
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 84.3 bits (207), Expect = 6e-16
Identities = 59/206 (28%), Positives = 103/206 (49%), Gaps = 18/206 (8%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK---HNFTNRILQEINMLSTIQDSV 452
F + ++G+G F VYQV +T YA+K +R K N + E ++L+ I
Sbjct: 140 FEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHP- 198
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+IV+ S+ K Y++ +F G+L + + ++ +
Sbjct: 199 --------FIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYT-----A 245
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYI 572
EI A+ +H+ I+H DLKP N+L+ +G++ L DFG+A + +S G EY+
Sbjct: 246 EIVSAVSHLHEK-GIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYM 304
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEI 598
APEI+R +D AD +S+G+++ E+
Sbjct: 305 APEIVRGKGHDKAADWWSVGILLYEM 330
>SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 338
Score = 84.0 bits (206), Expect = 8e-16
Identities = 67/251 (26%), Positives = 124/251 (48%), Gaps = 27/251 (10%)
Query: 389 DFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNF--TNRILQEINMLS 446
+F ++F +++GKG +STV+ V +T ++A+K + KH+ ++ E+ +L
Sbjct: 23 NFESVSQFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHDEHKIKKLRNEVLLLQ 82
Query: 447 TIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
++ + + +F S + + Y++T+ G+L + H+ ++ R
Sbjct: 83 SLNHPL---------LCKFYSEFEDETKIYLVTDLMLGGDL----RYHISQRKFNESVIR 129
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
IW +VE+ AL +IH S ++H D+KP N+L+ +G+ KLADF +A K+ ++
Sbjct: 130 IW--MVELVSALIYIH-SKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSN 186
Query: 567 ------GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGD-- 618
G Y+APE + + +D +SLG+ E V N + +R+ +
Sbjct: 187 MTVGRVGTPVYMAPETLIHAVSYKESDWWSLGITFYECLFQVRPFPNHLLINWIRASEEE 246
Query: 619 -LSDAGRLSSA 628
S A RLSSA
Sbjct: 247 KASSADRLSSA 257
>Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3
Length = 551
Score = 84.0 bits (206), Expect = 8e-16
Identities = 81/350 (23%), Positives = 145/350 (41%), Gaps = 32/350 (9%)
Query: 320 ITDDLYGHDQESSIFSPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQRS 379
+T L FS S+ N + + S S +M LRN+ + R
Sbjct: 194 VTSTLASESSSEGDFSADTSEINSNSDSLNS------SSLLMNGLRNNQRKAKRSLAPR- 246
Query: 380 INASIMKNPDFHLTTKFS----NVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFT 435
+ MK + + +F + ++G G F V++ G Y IK V+
Sbjct: 247 FDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE 306
Query: 436 NRI-----LQEINML-------STIQDSVTNDT--EGKEYIVEFI--SSWSHKGSFYIMT 479
+ L +N++ D T+D E +Y E SS S +I
Sbjct: 307 REVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQM 366
Query: 480 EFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLI 539
EFC+ G L+ +I++ + ++L+ ++ +I + +IH S ++H DLKP+N+ +
Sbjct: 367 EFCDKGTLEQWIEKR---RGEKLDKVLALELFEQITKGVDYIH-SKKLIHRDLKPSNIFL 422
Query: 540 TFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
+K+ DFG+ T L + K ++G Y++PE I Y D+++LGL++ E+
Sbjct: 423 VDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELL 482
Query: 600 ANVILP-DNGSAWHKLRSGDLSDAGRLSSAEIHSSSLFSNKKDHTNITDI 648
+ + LR G +SD + L +D N ++I
Sbjct: 483 HVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEI 532
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 84.0 bits (206), Expect = 8e-16
Identities = 68/292 (23%), Positives = 130/292 (44%), Gaps = 37/292 (12%)
Query: 327 HDQESSIFSPSPSKTNLQTPTKTSFDI---GPDSLAIMTKLRNDPTHLQPPE--KQRSIN 381
H+ ++ + + NL TP T + GP S ++ + P R+ N
Sbjct: 343 HNNATTTLDKNKNNANLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAAN 402
Query: 382 ASIMKNPDFHL-------------TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR 428
A K D + K++ + +G+G TVY TG++ AIK +
Sbjct: 403 AKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMN 462
Query: 429 PTKHNFTNRILQEINMLSTIQDSVTNDTEGKE-YIVEFISSWSHKGSFYIMTEFCENGNL 487
++ I+ EI ++ E K +V ++ S+ +++ E+ G+L
Sbjct: 463 LSQQPKKELIINEILVMR----------ENKHPNVVNYLDSYLVSEELWVVMEYLPGGSL 512
Query: 488 DAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKL 547
+ E +++ +I + E+ AL F+H + ++H D+K N+L+ +G++KL
Sbjct: 513 TDVVTETC------MDEGQIAAVCREVLQALEFLHAN-QVIHRDIKSDNILLGLDGSVKL 565
Query: 548 ADFGMATKL-PIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
DFG ++ P + K G ++APE++ Y + D++SLG+M IE+
Sbjct: 566 TDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEM 617
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 83.6 bits (205), Expect = 1e-15
Identities = 63/259 (24%), Positives = 121/259 (46%), Gaps = 19/259 (7%)
Query: 400 SIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGK 459
+++GKG F+ VY+ TGL+ AIK + + + + M+ +++ V + K
Sbjct: 16 NLLGKGSFAGVYRAESIHTGLEVAIKMI-------DKKAMYKAGMVQRVKNEVKIHCQLK 68
Query: 460 E-YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
I+E + + Y++ E C NG ++ +++ V + + + +I +
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRV----KPFSENEARHFMHQIITGM 124
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPI-EDKSFENEGDREYIAPEII 577
++H S I+H DL +N+L+T N+K+ADFG+AT+L + +K + G YI+PEI
Sbjct: 125 LYLH-SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIA 183
Query: 578 RDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSSAEIHSSSLF- 636
+ +D++SLG M + D + + L L+D + I + L
Sbjct: 184 TRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIH 243
Query: 637 ----SNKKDHTNITDITTH 651
N D +++ + H
Sbjct: 244 QLLRRNPADRLSLSSVLDH 262
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 83.6 bits (205), Expect = 1e-15
Identities = 88/308 (28%), Positives = 138/308 (44%), Gaps = 36/308 (11%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRI-LQEINMLSTIQDSVTN 454
+ + +G+G + TV + TG AIK N+I ++EI L
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHH---- 59
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
E +V I + K +++ EF ++ LD +H LE R+ K + +I
Sbjct: 60 -----ENLVNLIEVFRQKKKIHLVFEFIDHTVLDEL--QHYC---HGLESKRLRKYLFQI 109
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIE-DKSFENEGDREYIA 573
A+ ++H + +I+H D+KP N+L++ G KL DFG A L D + R Y A
Sbjct: 110 LRAIDYLHSN-NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRA 168
Query: 574 PE-IIRDGIYDFRADIFSLGLMMIEIA-ANVILPDNG--SAWHK--LRSGDLSDAGRLSS 627
PE +++D Y DI++LG M+IE+A N LP + HK L+ G+LS
Sbjct: 169 PELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSP------ 222
Query: 628 AEIHSSSLFSNKKDHTNIT-DITTHETKIPAWVPKFLLDGISLERTIRWMIEPDYRDRPS 686
H ++FS + H PK L+G+ L + ++ D DR S
Sbjct: 223 ---HLQNIFSKSPIFAGVVLPQVQHPKNARKKYPK--LNGL-LADIVHACLQIDPADRIS 276
Query: 687 ASDLLRTE 694
+SDLL E
Sbjct: 277 SSDLLHHE 284
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 83.6 bits (205), Expect = 1e-15
Identities = 56/205 (27%), Positives = 102/205 (49%), Gaps = 16/205 (7%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTN 454
K++ +G+G TV+ T G + AIK + K I+ EI ++ +++
Sbjct: 248 KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNP--- 304
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
IV F+ S+ +++ E+ G+L V+ + +++ +I + E
Sbjct: 305 ------NIVNFLDSYLVGDELFVVMEYLAGGSLT-----DVVTETACMDEAQIAAVCREC 353
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYIA 573
AL F+H + ++H D+K NVL+ EG++KL DFG ++ P + K G ++A
Sbjct: 354 LQALEFLHAN-QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMA 412
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEI 598
PE++ Y + DI+SLG+M IE+
Sbjct: 413 PEVVTRKAYGPKVDIWSLGIMAIEM 437
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 83.6 bits (205), Expect = 1e-15
Identities = 63/259 (24%), Positives = 121/259 (46%), Gaps = 19/259 (7%)
Query: 400 SIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGK 459
+++GKG F+ VY+ +GL+ AIK + + + + M+ +Q+ V + K
Sbjct: 16 NLLGKGSFAGVYRAESIHSGLEVAIKMI-------DKKAMYKAGMVQRVQNEVKIHCQLK 68
Query: 460 E-YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
I+E + + Y++ E C NG ++ +++ V + + + +I +
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRV----KPFSENEARHFMHQIITGM 124
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPI-EDKSFENEGDREYIAPEII 577
++H S I+H DL +N+L+T N+K+ADFG+AT+L + +K + G YI+PEI
Sbjct: 125 LYLH-SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIA 183
Query: 578 RDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSSAEIHSSSLF- 636
+ +D++SLG M + D + + L L+D + I + L
Sbjct: 184 TRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIH 243
Query: 637 ----SNKKDHTNITDITTH 651
N D +++ + H
Sbjct: 244 QLLRRNPADRLSLSSVLDH 262
>7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1726
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/207 (29%), Positives = 104/207 (49%), Gaps = 20/207 (9%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEG 458
V +G G F VY+ E A K + + + EI++LS I+
Sbjct: 40 VGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKHP------- 92
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
IVE ++S +++ E+C+ G LD+ + E ++ L + +I + + L
Sbjct: 93 --NIVELYEAFSIDDKLWMLIEYCDGGALDSIMVE----LEKPLTEPQIAYVCKHMTEGL 146
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN-EGDREYIAPEII 577
F+H + ++H DLK NVL+T EG +KLADFG++ K + + G ++APE++
Sbjct: 147 TFLHRN-KVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELV 205
Query: 578 -----RDGIYDFRADIFSLGLMMIEIA 599
RD YD + DI+SLG+ +IE+A
Sbjct: 206 LCETFRDNPYDHKVDIWSLGITLIELA 232
>At1g66980_2 [T] KOG1187 Serine/threonine protein kinase
Length = 345
Score = 83.6 bits (205), Expect = 1e-15
Identities = 67/211 (31%), Positives = 109/211 (50%), Gaps = 25/211 (11%)
Query: 397 SNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDT 456
S ++G+G F VY+ T + G A+K ++ TK N + I + M T ++ +
Sbjct: 33 SFAEVVGRGGFGIVYKGTLSD-GRVVAVKVLKDTKGNGEDFINEVATMSRTSHLNIVS-- 89
Query: 457 EGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR-IWKIIVEIC 515
++ F S S + Y EF ENG+LD FI + K DW +++I + +
Sbjct: 90 -----LLGFCSEGSKRAIIY---EFLENGSLDKFI----LGKTSVNMDWTALYRIALGVA 137
Query: 516 LALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKS----FENEGDR 569
L ++H SC IVH D+KP NVL+ K++DFG+A KL + +S + G
Sbjct: 138 HGLEYLHHSCKTRIVHFDIKPQNVLLDDSFCPKVSDFGLA-KLCEKKESILSMLDTRGTI 196
Query: 570 EYIAPEIIRD--GIYDFRADIFSLGLMMIEI 598
YIAPE+I G ++D++S G++++EI
Sbjct: 197 GYIAPEMISRVYGNVSHKSDVYSYGMLVLEI 227
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 83.2 bits (204), Expect = 1e-15
Identities = 64/215 (29%), Positives = 110/215 (50%), Gaps = 37/215 (17%)
Query: 400 SIMGKGQFSTVYQVTFPETGLKYAIKSVR---PTKHNFTNRILQ---------------- 440
+I+GKG FS+V+ E G K A+K VR + +F ++ Q
Sbjct: 61 AIIGKGNFSSVHLTRRKEDGTKCALK-VRYQSTLQFSFPSKFFQQVEKRAMRGKCFFVDN 119
Query: 441 EINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQ 500
E+ MLS IQ ++I+ I ++S + ++I+ E + G+L I K
Sbjct: 120 EVEMLSLIQH---------DHIISIIDAFSTENQYFIVFEHAQYGDL-----YETIRKNG 165
Query: 501 RLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIED 560
R+E+ I +++ AL ++H+ ++VH D+KP N+L+ + ++KL DFG+A I
Sbjct: 166 RIEEPDAAIITLQVASALNYLHER-NVVHRDVKPENLLLVDKFSVKLCDFGLACH--ILG 222
Query: 561 KSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMM 595
+ G Y APE++R+ Y R DI+SLG+++
Sbjct: 223 PLYRICGTPTYCAPEVLRETGYSTRCDIWSLGVVL 257
>At5g66850 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 83.2 bits (204), Expect = 1e-15
Identities = 59/220 (26%), Positives = 105/220 (46%), Gaps = 27/220 (12%)
Query: 392 LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-----PTKHNFTNRILQEINMLS 446
+ +++ ++G+G F +VY + ETG A+K V P ++ QEI +LS
Sbjct: 1 MNSQWKKGKLIGRGTFGSVYVASNSETGALCAMKEVELFPDDPKSAECIKQLEQEIKLLS 60
Query: 447 TIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
+Q IV++ S + + F+I E+ G+++ +I++H + +
Sbjct: 61 NLQHP---------NIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESV---- 107
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
+ I L ++H+ VH D+K AN+L+ G +KLADFGMA L + +
Sbjct: 108 VRNFTRHILSGLAYLHNK-KTVHRDIKGANLLVDASGVVKLADFGMAKHLTGQRADLSLK 166
Query: 567 GDREYIAPEIIRDGIYD--------FRADIFSLGLMMIEI 598
G ++APE++ + F DI+SLG +IE+
Sbjct: 167 GSPYWMAPEVLMQAVMQKDSNPDLAFAVDIWSLGCTIIEM 206
>At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 354
Score = 83.2 bits (204), Expect = 1e-15
Identities = 67/244 (27%), Positives = 113/244 (45%), Gaps = 21/244 (8%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEG 458
+ ++GKG V V T +A+K ++ T R + Q+ N +
Sbjct: 71 IKVIGKGSSGNVQLVKHKLTQQFFALKVIQLNTEESTCRAIS--------QELRINLSSQ 122
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
Y+V S+ H G I+ EF + G+L ++ K ++ + + I + L
Sbjct: 123 CPYLVSCYQSFYHNGLVSIILEFMDGGSL-----ADLLKKVGKVPENMLSAICKRVLRGL 177
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYIAPEI 576
+IH I+H DLKP+N+LI G +K+ DFG+ +K+ S N G Y++PE
Sbjct: 178 CYIHHERRIIHRDLKPSNLLINHRGEVKITDFGV-SKILTSTSSLANSFVGTYPYMSPER 236
Query: 577 IRDGIYDFRADIFSLGLMMIEIAAN---VILPDNGSAWHKLRSGDLSDAGRLSSAEIHSS 633
I +Y ++DI+SLGL+++E A P++ W + +L DA + S
Sbjct: 237 ISGSLYSNKSDIWSLGLVLLECATGKFPYTPPEHKKGWSSVY--ELVDAIVENPPPCAPS 294
Query: 634 SLFS 637
+LFS
Sbjct: 295 NLFS 298
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 83.2 bits (204), Expect = 1e-15
Identities = 91/337 (27%), Positives = 151/337 (44%), Gaps = 35/337 (10%)
Query: 385 MKNPDFHLTTKFSNVSIMG----KGQFSTVYQVTFPETGLKYAIK--SVRPTKHNFTNRI 438
M + FH + N ++G KG + VY E G AIK S+ N I
Sbjct: 5 MTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIGLDLENGDFVAIKQVSLENIGQEDLNTI 64
Query: 439 LQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAK 498
+QEI++L + + IV+++ S K +I+ E+ ENG+L I+ + K
Sbjct: 65 MQEIDLLKNLNH---------KNIVKYLGSLKTKTHLHIILEYVENGSLANIIKPN---K 112
Query: 499 QQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPI 558
+ + I ++ L ++H+ ++H D+K AN+L T EG +KLADFG+ATKL
Sbjct: 113 FGPFPESLVTVYIAQVLEGLVYLHEQ-GVIHRDIKGANILTTKEGLVKLADFGVATKLNE 171
Query: 559 ED-KSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANV-----ILPDNGSAWH 612
D + G ++APE+I +DI+S+G +IE+ V + P A +
Sbjct: 172 ADFNTHSVVGTPYWMAPEVIELSGVCAASDIWSVGCTIIELLTCVPPYYDLQP--MPALY 229
Query: 613 KLRSGDLSDAGRLSSAEIHSSSLFSNKKDHTNITDITTHETKIPAWV---PKFLLDGISL 669
++ D S +I KKD D T + W+ + L +
Sbjct: 230 RIVQDDTPPIPDSLSPDITDFLRLCFKKDSRQRPDAKTLLSH--PWIRNSRRALRSSLRH 287
Query: 670 ERTIRWMIEPD---YRDRPSASDLLRTEELEYVELTR 703
TIR+M E D +D + +++ + E VE+T+
Sbjct: 288 SGTIRYMKETDSSSEKDAEGSQEVVESVSAEKVEVTK 324
>At1g66920 [T] KOG1187 Serine/threonine protein kinase
Length = 609
Score = 83.2 bits (204), Expect = 1e-15
Identities = 68/216 (31%), Positives = 109/216 (49%), Gaps = 26/216 (12%)
Query: 392 LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDS 451
+T F+ V +G+G F VY+ T + G A+K ++ K N + E+ +S Q S
Sbjct: 297 ITNSFAEV--VGRGGFGIVYRGTLSD-GRMVAVKVLKDLKGNNGEDFINEVASMS--QTS 351
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR-IWKI 510
N IV + S I+ EF ENG+LD FI +K+ DWR ++ I
Sbjct: 352 HVN-------IVTLLGFCSEGYKRAIIYEFMENGSLDKFIS----SKKSSTMDWRELYGI 400
Query: 511 IVEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKS----FE 564
+ + L ++H C IVH D+KP NVL+ + K++DFG+A KL +S +
Sbjct: 401 ALGVARGLEYLHHGCRTRIVHFDIKPQNVLLDDNLSPKVSDFGLA-KLCERKESILSLMD 459
Query: 565 NEGDREYIAPEIIRD--GIYDFRADIFSLGLMMIEI 598
G YIAPE+ G ++D++S G+++++I
Sbjct: 460 TRGTIGYIAPEVFSRVYGSVSHKSDVYSYGMLVLDI 495
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 82.8 bits (203), Expect = 2e-15
Identities = 53/200 (26%), Positives = 100/200 (49%), Gaps = 19/200 (9%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPT---KHNFTNRILQEINMLSTIQDSVTNDTEG 458
+GKG+F VY E+ A+K + + K +++ +EI + + +Q
Sbjct: 15 LGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP------- 67
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
I+ + + Y++ E+ G L +Q K ++L++ R II E+ AL
Sbjct: 68 --NILRLYNYFHDARRVYLILEYAPRGELYKELQ-----KSEKLDEQRTATIIEEVADAL 120
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
+ HD ++H D+KP N+L+ F G +K+ADFG + P+ ++ G +Y+ PE+I
Sbjct: 121 TYCHDK-KVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERK-TMCGTLDYLPPEMIE 178
Query: 579 DGIYDFRADIFSLGLMMIEI 598
YD + D++ +G++ E+
Sbjct: 179 GRTYDEKVDLWCIGVLCYEL 198
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 82.8 bits (203), Expect = 2e-15
Identities = 67/221 (30%), Positives = 111/221 (49%), Gaps = 20/221 (9%)
Query: 385 MKNPDFHLTTKFSNVSIMG----KGQFSTVYQVTFPETGLKYAIK--SVRPTKHNFTNRI 438
M + FH + N ++G KG + VY+ E G AIK S+ N I
Sbjct: 5 MTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIVQEDLNTI 64
Query: 439 LQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAK 498
+QEI++L + + IV+++ S K +I+ E+ ENG+L I+ + K
Sbjct: 65 MQEIDLLKNLNH---------KNIVKYLGSSKTKTHLHIILEYVENGSLANIIKPN---K 112
Query: 499 QQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPI 558
+ + I ++ L ++H+ ++H D+K AN+L T EG +KLADFG+ATKL
Sbjct: 113 FGPFPESLVAVYIAQVLEGLVYLHEQ-GVIHRDIKGANILTTKEGLVKLADFGVATKLNE 171
Query: 559 EDKSFEN-EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
D + + G ++APE+I +DI+S+G +IE+
Sbjct: 172 ADVNTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIEL 212
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 82.4 bits (202), Expect = 2e-15
Identities = 60/199 (30%), Positives = 95/199 (47%), Gaps = 19/199 (9%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQEINMLSTIQDSVTNDTE 457
++GKG F+ Y+ T ETG YA+K + R K + +IL EI + +Q
Sbjct: 28 LLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQH------- 80
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
+IV F + + YI E C +L H+ + L + + + +I
Sbjct: 81 --RHIVRFSHHFEDADNIYIFLELCSRKSL-----AHIWKARHTLLEPEVRYYLRQILSG 133
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYIAPEI 576
L+++H I+H DLK N IT LK+ DFG+A +L P E + G Y+APE+
Sbjct: 134 LKYLHQR-GILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEV 192
Query: 577 IRDGIYDFRADIFSLGLMM 595
+ + AD++SLG +M
Sbjct: 193 LLRQGHGPEADVWSLGCVM 211
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 82.0 bits (201), Expect = 3e-15
Identities = 74/292 (25%), Positives = 127/292 (43%), Gaps = 25/292 (8%)
Query: 310 NTELTSMLRQITDDLYGHDQESSIFSPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPT 369
NT + +I+ + S I SP K N + P + +S I + +R +
Sbjct: 25 NTSRINKPWRISHSPQQRNPNSKIPSPVREKLN-RLPVNNKKFLDMESSKIPSPIRKATS 83
Query: 370 HLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP 429
E ++ + DF L K +GKG+F VY V TG A+K +
Sbjct: 84 SKMIHENKKLPKFKSLSLDDFELGKK------LGKGKFGKVYCVRHRSTGYICALKVMEK 137
Query: 430 T---KHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGN 486
K+N + +E+ IQ S+ + K Y + + Y++ E+ NG
Sbjct: 138 EEIIKYNLQKQFRREVE----IQTSLNHPNLTKSY-----GYFHDEKRVYLLMEYLVNGE 188
Query: 487 LDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLK 546
+ ++ H D+ I +I AL ++H +I+H D+KP N+LI F +K
Sbjct: 189 MYKLLRLHGPFNDILASDY-----IYQIANALDYMHKK-NIIHRDIKPENILIGFNNVIK 242
Query: 547 LADFGMATKLPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
L DFG + P E++ G +Y++PE++ YD D ++LG++ E+
Sbjct: 243 LTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFEL 294
>At4g22130 [T] KOG1187 Serine/threonine protein kinase
Length = 338
Score = 82.0 bits (201), Expect = 3e-15
Identities = 62/211 (29%), Positives = 104/211 (48%), Gaps = 15/211 (7%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T FS +I+G+G VY+ FP G AIK + N + +E N L ++V
Sbjct: 27 TNSFSQENIIGEGSLGRVYRAEFPN-GKIMAIKKI----DNAALSLQEEDNFL----EAV 77
Query: 453 TNDTEGKE-YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
+N + + IV + G ++ E+ NGNLD + + + R+ K+
Sbjct: 78 SNMSRLRHPNIVPLAGYCTEHGQRLLVYEYVGNGNLDDTLHTNDDRSMNLTWNARV-KVA 136
Query: 512 VEICLALRFIHDSC--SIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--G 567
+ AL ++H+ C SIVH + K AN+L+ E N L+D G+A P ++ + G
Sbjct: 137 LGTAKALEYLHEVCLPSIVHRNFKSANILLDEELNPHLSDSGLAALTPNTERQVSTQVVG 196
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
Y APE GIY ++D+++ G++M+E+
Sbjct: 197 SFGYSAPEFALSGIYTVKSDVYTFGVVMLEL 227
>At3g12200 [R] KOG0589 Serine/threonine protein kinase
Length = 571
Score = 82.0 bits (201), Expect = 3e-15
Identities = 55/201 (27%), Positives = 106/201 (52%), Gaps = 16/201 (7%)
Query: 404 KGQFSTVYQVTFPETGLKYAIKSVRPTKHN--FTNRILQEINMLSTIQDSVTNDTEGKEY 461
+G+ S+ + V KYA+K + KH LQE+ +LS++++ Y
Sbjct: 27 RGKSSSDFVVLHDIEDKKYAMKKICLAKHTDKLKQTALQEMKLLSSLKNP---------Y 77
Query: 462 IVEFISSW-SHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
IV + SW + + I T + E GN+ I++ A+ + + RI+K + ++ LA+ +
Sbjct: 78 IVHYEDSWIDNDNNACIFTAYYEGGNMANAIKK---ARGKLFPEERIFKWLAQLLLAVNY 134
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG 580
+H + +VH+DL +N+ + + +++L ++G+A + E G + PE++ D
Sbjct: 135 LHSN-RVVHMDLTCSNIFLPKDDHVQLGNYGLAKLINPEKPVSMVSGISNSMCPEVLEDQ 193
Query: 581 IYDFRADIFSLGLMMIEIAAN 601
Y +++DI+SLG M EI A+
Sbjct: 194 PYGYKSDIWSLGCCMYEITAH 214
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 82.0 bits (201), Expect = 3e-15
Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 46/238 (19%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT---KHNFTNRILQEINMLSTIQDSV 452
F + + +G F V+ TG +AIK ++ + N RILQE N+L T++
Sbjct: 670 FEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNILITVR--- 726
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
++V F S++ + + Y++ E+ G+L + +Q+ + E RI+ I
Sbjct: 727 ------YPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDE---EIARIY--IA 775
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMA------------------- 553
E+ LAL ++H S IVH DLKP N+LI + G++KL DFG++
Sbjct: 776 ELVLALEYLH-SLKIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGLINNTIDLSGHESDVS 834
Query: 554 --TKLPIEDKSFENE-------GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANV 602
T K+ E E G +Y+APEI+ + + AD +S G+++ E+ +
Sbjct: 835 PRTNSHHFQKNQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTGI 892
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 82.0 bits (201), Expect = 3e-15
Identities = 68/251 (27%), Positives = 121/251 (48%), Gaps = 18/251 (7%)
Query: 356 DSLAIMTKLRNDPTH-LQPPEKQRSINASI---MKNPDFHLTTKFSNVSIMGKGQFSTVY 411
D+ + +LR++ H +P EK+R N + M D F+ V ++GKG F V
Sbjct: 327 DAFNDIARLRDEVRHDRRPNEKRRMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVL 386
Query: 412 QVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKE-YIVEFISSWS 470
T YA+K +R + I+Q +M + + G+ ++V S +
Sbjct: 387 LAERRGTDELYAVKVLRK------DVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQ 440
Query: 471 HKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHL 530
+ + E+C+ G+L +Q++ R ++ VE+ +AL F+H+ I++
Sbjct: 441 TMDRLFFVMEYCKGGDLMYHMQQY-----GRFKESVAIFYAVEVAIALFFLHER-DIIYR 494
Query: 531 DLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-GDREYIAPEIIRDGIYDFRADIF 589
DLK N+L+ EG++KL DFG++ + E ++ G Y+APEI+ Y AD +
Sbjct: 495 DLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWW 554
Query: 590 SLGLMMIEIAA 600
S G+++ E A
Sbjct: 555 SFGVLLFEFMA 565
>7292830 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 334
Score = 82.0 bits (201), Expect = 3e-15
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 15/211 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKH-NFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G+G + V ++ +T A+K + T + +R++ ++++ D
Sbjct: 52 LGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDC--------P 103
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
Y V F + +G +I E +LD F + V R+E+ + KI + + AL +
Sbjct: 104 YTVHFYGAMYREGDVWICMEVMST-SLDKFYPK-VFLHDLRMEESVLGKIAMSVVSALHY 161
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEII--- 577
+H ++H D+KP+N+LI G +K+ DFG++ L + G + Y+APE I
Sbjct: 162 LHAQLKVIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQ 221
Query: 578 -RDGIYDFRADIFSLGLMMIEIAANVILPDN 607
YD R+D++SLG+ MIE+A DN
Sbjct: 222 GNPAQYDIRSDVWSLGIGMIEMATGRYPYDN 252
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 81.6 bits (200), Expect = 4e-15
Identities = 65/250 (26%), Positives = 115/250 (46%), Gaps = 26/250 (10%)
Query: 363 KLRNDPTHLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKY 422
K+ +D + +P K+ S KN F S++G G +STV T +T +Y
Sbjct: 149 KIEHDSSSQKPIAKESS---KAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRY 205
Query: 423 AIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFC 482
A K + N I Q+ +I+ + +V S++ + S Y + E+
Sbjct: 206 AAKVL-----NKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYA 260
Query: 483 ENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFE 542
NG+ + ++ K L++ +I A+ ++H + I+H D+KP N+L+ E
Sbjct: 261 PNGDFLSLMK-----KYGSLDETCARYYAAQIIDAIDYLHSN-GIIHRDIKPENILLDGE 314
Query: 543 GNLKLADFGMATKL---------PIEDKSFENE---GDREYIAPEIIRDGIYDFRADIFS 590
+KL DFG A L P D S ++ G EY++PE++ D D+R DI++
Sbjct: 315 MKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWA 374
Query: 591 LGLMMIEIAA 600
G ++ ++ A
Sbjct: 375 FGCILFQMIA 384
>Hs15011880 [T] KOG0201 Serine/threonine protein kinase
Length = 416
Score = 81.6 bits (200), Expect = 4e-15
Identities = 71/239 (29%), Positives = 119/239 (49%), Gaps = 29/239 (12%)
Query: 364 LRNDPTHLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYA 423
+ + P +Q P Q +I +P+ L TK + GKG F V++ T A
Sbjct: 1 MAHSPVAVQVPGMQNNI-----ADPE-ELFTKLERI---GKGSFGEVFKGIDNRTQQVVA 51
Query: 424 IKSVRPTK-HNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFC 482
IK + + + I QEI +LS S Y+ ++ S+ +I+ E+
Sbjct: 52 IKIIDLEEAEDEIEDIQQEITVLSQCDSS---------YVTKYYGSYLKGSKLWIIMEYL 102
Query: 483 ENGN-LDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITF 541
G+ LD + + ++++I ++ EI L ++H I H D+K ANVL++
Sbjct: 103 GGGSALD-------LLRAGPFDEFQIATMLKEILKGLDYLHSEKKI-HRDIKAANVLLSE 154
Query: 542 EGNLKLADFGMATKL-PIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
+G++KLADFG+A +L + K G ++APE+I+ YD +ADI+SLG+ IE+A
Sbjct: 155 QGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELA 213
>ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 516
Score = 81.6 bits (200), Expect = 4e-15
Identities = 65/195 (33%), Positives = 103/195 (52%), Gaps = 24/195 (12%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
++G+G STVY G + A+K V P K T + +EI MLSTI+ E
Sbjct: 9 VIGEGASSTVYSGVSAR-GEEVAVKVV-PRKGRSTGMVYREIEMLSTIKH---------E 57
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
IV + + K Y++ E C+ NL +F+ E+ + + L KI+ I LR
Sbjct: 58 NIVGIVGRFESKKHVYMVEELCDF-NLVSFLNEYEVDEDVAL------KILRMILCGLRH 110
Query: 521 IHDSCSIVHLDLKPANVLITFEGN-LKLADFGMATKLPIEDKSFENEGDREYIAPEIIRD 579
IH S I+H DLK N+L+ +GN +K+ DFG++ +E+ + E G +Y+APE++
Sbjct: 111 IH-SLGIIHRDLKLGNILL--KGNTVKICDFGLSCY--VEENNSEFCGTMDYLAPEVVDG 165
Query: 580 GIYDFRADIFSLGLM 594
Y F D++S G++
Sbjct: 166 KKYSFGVDMWSAGVV 180
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 81.3 bits (199), Expect = 5e-15
Identities = 58/206 (28%), Positives = 104/206 (50%), Gaps = 12/206 (5%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++G+G ++ V V + YA+K V+ + ++I+ + T + V
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDD----EDIDWVQT-EKHVFEQ 306
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++V S + +++ E+ G+L +Q +Q++L + EIC
Sbjct: 307 ASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQ-----RQRKLPEEHARFYAAEIC 361
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDREYIAP 574
+AL F+H+ I++ DLK NVL+ +G++KL D+GM + L D + G YIAP
Sbjct: 362 IALNFLHER-GIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAP 420
Query: 575 EIIRDGIYDFRADIFSLGLMMIEIAA 600
EI+R Y F D ++LG++M E+ A
Sbjct: 421 EILRGEEYGFSVDWWALGVLMFEMMA 446
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 81.3 bits (199), Expect = 5e-15
Identities = 58/206 (28%), Positives = 104/206 (50%), Gaps = 12/206 (5%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++G+G ++ V V + YA+K V+ + ++I+ + T + V
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDD----EDIDWVQT-EKHVFEQ 306
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++V S + +++ E+ G+L +Q +Q++L + EIC
Sbjct: 307 ASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQ-----RQRKLPEEHARFYAAEIC 361
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDREYIAP 574
+AL F+H+ I++ DLK NVL+ +G++KL D+GM + L D + G YIAP
Sbjct: 362 IALNFLHER-GIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAP 420
Query: 575 EIIRDGIYDFRADIFSLGLMMIEIAA 600
EI+R Y F D ++LG++M E+ A
Sbjct: 421 EILRGEEYGFSVDWWALGVLMFEMMA 446
>CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 294
Score = 81.3 bits (199), Expect = 5e-15
Identities = 57/203 (28%), Positives = 102/203 (50%), Gaps = 15/203 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTK---HNFTNRILQEINMLSTIQDSVTNDTEG 458
+GKGQFS V++ L A+K ++ + L+EI++L +
Sbjct: 29 IGKGQFSEVFRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKEIDLLKQLNHV------- 81
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
++ + +S+ I+ E E G++ I+ H + + + IWK V++ AL
Sbjct: 82 --NVIRYYASFIDNNQLNIVLELAEAGDMSRMIK-HFKKGGRLIPEKTIWKYFVQLARAL 138
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN-EGDREYIAPEII 577
+H S I+H D+KPANV IT G +KL D G+ + + + G Y++PE I
Sbjct: 139 AHMH-SKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERI 197
Query: 578 RDGIYDFRADIFSLGLMMIEIAA 600
++ Y+F++D++S G ++ E+AA
Sbjct: 198 QESGYNFKSDLWSTGCLLYEMAA 220
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 81.3 bits (199), Expect = 5e-15
Identities = 60/210 (28%), Positives = 114/210 (53%), Gaps = 22/210 (10%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVT 453
+FS + ++G+G F VY+ + + AIK + + I +EI++LS +
Sbjct: 14 RFSQIELIGRGSFGDVYKAFDKDLNKEVAIKVIDLEESEDEIEDIQKEISVLSQCRCP-- 71
Query: 454 NDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVE 513
YI E+ S+ H+ +I+ E+ G++ +Q + L++ I I +
Sbjct: 72 -------YITEYYGSYLHQTKLWIIMEYMAGGSVADLLQSN-----NPLDETSIACITRD 119
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP---IEDKSFENEGDRE 570
+ A+ ++H+ I H D+K AN+L++ G++K+ADFG++ +L K+F G
Sbjct: 120 LLHAVEYLHNEGKI-HRDIKAANILLSENGDVKVADFGVSAQLTRTISRRKTF--VGTPF 176
Query: 571 YIAPEIIRDGI-YDFRADIFSLGLMMIEIA 599
++APE+I++ Y+ +ADI+SLG+ +IE+A
Sbjct: 177 WMAPEVIQNSEGYNEKADIWSLGITVIEMA 206
>At2g02800 [T] KOG1187 Serine/threonine protein kinase
Length = 426
Score = 81.3 bits (199), Expect = 5e-15
Identities = 94/396 (23%), Positives = 172/396 (42%), Gaps = 59/396 (14%)
Query: 330 ESSIFSPSPSKTNLQT--PTKTSFDIGPDSLAI--MTKLRNDPTHLQPPEKQRSINASIM 385
+SS SP + +L + +KTS P SL+I + + + PT E S N
Sbjct: 12 DSSSHSPHANSASLSSRVSSKTSRSTVPSSLSINSYSSVESLPTPRTEGEILSSPNLKAF 71
Query: 386 K-NPDFHLTTKFSNVSIMGKGQFSTVYQ---------VTFPETGLKYAIKSVRPTKHNFT 435
N + T F S++G+G F V++ + P +G+ A+K ++ +
Sbjct: 72 TFNELKNATRNFRPDSLLGEGGFGYVFKGWIDGTTLTASKPGSGIVVAVKKLKTEGYQGH 131
Query: 436 NRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHV 495
L E+N L + +V+ + + ++ EF G+L+ H+
Sbjct: 132 KEWLTEVNYLGQLSHP---------NLVKLVGYCVEGENRLLVYEFMPKGSLE----NHL 178
Query: 496 IAKQQRLEDWRI-WKIIVEICLALRFIHDSCS-IVHLDLKPANVLITFEGNLKLADFGMA 553
+ + W I K+ + L F+HD+ S +++ D K AN+L+ E N KL+DFG+A
Sbjct: 179 FRRGAQPLTWAIRMKVAIGAAKGLTFLHDAKSQVIYRDFKAANILLDAEFNSKLSDFGLA 238
Query: 554 TKLPIEDK---SFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSA 610
P DK S + G Y APE + G ++D++S G++++E+ +
Sbjct: 239 KAGPTGDKTHVSTQVMGTHGYAAPEYVATGRLTAKSDVYSFGVVLLELLSG--------- 289
Query: 611 WHKLRSGDLSDAGRLSSAEIHSSSLFSNKKDHTNITDITTHETKIPAWVPK---FLLDGI 667
R+ D S G S ++ +K+ I D T++ P+ + +
Sbjct: 290 ---RRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMD-----TRLGGQYPQKGAYTAASL 341
Query: 668 SLERTIRWMIEPDYRDRPSASDLLRTEELEYVELTR 703
+L+ + PD + RP S++L +L+ +E T+
Sbjct: 342 ALQ-----CLNPDAKLRPKMSEVL--AKLDQLESTK 370
>Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 357
Score = 81.3 bits (199), Expect = 5e-15
Identities = 60/212 (28%), Positives = 108/212 (50%), Gaps = 12/212 (5%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T + + +GKG + VY+VT G A+K + P + I E N+L + +
Sbjct: 24 TDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVS-DMDEEIEAEYNILQFLPN-- 80
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+ K Y + + + G +++ E C G++ ++ ++ QRL++ I I+
Sbjct: 81 -HPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG-LLRCGQRLDEAMISYILY 138
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREY 571
L L+ +H++ I+H D+K N+L+T EG +KL DFG++ +L + + G +
Sbjct: 139 GALLGLQHLHNN-RIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFW 197
Query: 572 IAPEIIR-----DGIYDFRADIFSLGLMMIEI 598
+APE+I D YD R D++SLG+ IE+
Sbjct: 198 MAPEVIACEQQYDSSYDARCDVWSLGITAIEL 229
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 80.9 bits (198), Expect = 6e-15
Identities = 66/231 (28%), Positives = 117/231 (50%), Gaps = 25/231 (10%)
Query: 373 PPEKQ--RSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT 430
PP +Q + S+ K P+ F + +G+G + +VY+ ETG AIK V P
Sbjct: 9 PPRRQLKKLDEDSLTKQPE----EVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQV-PV 63
Query: 431 KHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAF 490
+ + I++EI+++ ++V++ S+ +I+ E+C G++
Sbjct: 64 ESDL-QEIIKEISIMQQCDSP---------HVVKYYGSYFKNTDLWIVMEYCGAGSVSDI 113
Query: 491 IQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADF 550
I+ + + L + I I+ L ++H I H D+K N+L+ EG+ KLADF
Sbjct: 114 IR----LRNKTLTEDEIATILQSTLKGLEYLHFMRKI-HRDIKAGNILLNTEGHAKLADF 168
Query: 551 GMATKLPIEDKSFENE--GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
G+A +L + + N G ++APE+I++ Y+ ADI+SLG+ IE+A
Sbjct: 169 GVAGQL-TDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMA 218
>At5g11015 [T] KOG1187 Serine/threonine protein kinase
Length = 402
Score = 80.9 bits (198), Expect = 6e-15
Identities = 51/209 (24%), Positives = 106/209 (50%), Gaps = 16/209 (7%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T+ F +I+G+G F VY T E + A+K + + E+ +LS +Q
Sbjct: 107 TSGFKESNILGQGGFGCVYSATL-ENNISAAVKKLDCANEDAAKEFKSEVEILSKLQHP- 164
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
I+ + ++ + +I+ E N +L++ + + Q W + KI
Sbjct: 165 --------NIISLLGYSTNDTARFIVYELMPNVSLESHLHG---SSQGSAITWPMRMKIA 213
Query: 512 VEICLALRFIHDSC--SIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDR 569
+++ L ++H+ C +I+H DLK +N+L+ N K++DFG+A ++K+ + G
Sbjct: 214 LDVTRGLEYLHEHCHPAIIHRDLKSSNILLDSNFNAKISDFGLAVVDGPKNKNHKLSGTV 273
Query: 570 EYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
Y+APE + +G ++D+++ G++++E+
Sbjct: 274 GYVAPEYLLNGQLTEKSDVYAFGVVLLEL 302
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 80.9 bits (198), Expect = 6e-15
Identities = 55/202 (27%), Positives = 100/202 (49%), Gaps = 20/202 (9%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHN--FTNRILQEINMLSTIQDSVTNDTEGK 459
+G G FS V++ G + AIK + + N ++ EI +L I
Sbjct: 18 IGSGSFSVVWEARHRVDGTEVAIKEIAMDRLNKKLQESLMSEIFILRRINHP-------- 69
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALR 519
I+ I G +++ E+C+ G+L ++Q H I + + + + ++ L+
Sbjct: 70 -NIIRLIDMIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKHF-----MQQLAAGLQ 123
Query: 520 FIHDSCSIVHLDLKPANVLITFEGN---LKLADFGMATKLPIEDKSFENEGDREYIAPEI 576
+ D+ +I+H DLKP N+L++ N LK+ADFG A L + G Y+APEI
Sbjct: 124 VLRDN-NIIHRDLKPQNLLLSTNENDADLKIADFGFARSLQPRGLAETLCGSPLYMAPEI 182
Query: 577 IRDGIYDFRADIFSLGLMMIEI 598
++ YD +AD++S+G ++ ++
Sbjct: 183 MQLQKYDAKADLWSVGAILFQL 204
>At1g66930 [T] KOG1187 Serine/threonine protein kinase
Length = 674
Score = 80.9 bits (198), Expect = 6e-15
Identities = 65/210 (30%), Positives = 108/210 (50%), Gaps = 22/210 (10%)
Query: 397 SNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDT 456
S ++G+G F VY+ T + G A+K ++ +K N + + E++ +S Q S N
Sbjct: 347 SFAEVVGRGGFGIVYRGTLCD-GRMVAVKVLKESKGNNSEDFINEVSSMS--QTSHVNIV 403
Query: 457 EGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICL 516
++ F S S + Y EF ENG+LD FI E L+ ++ I + +
Sbjct: 404 S----LLGFCSEGSRRAIIY---EFLENGSLDKFISEKTSVI---LDLTALYGIALGVAR 453
Query: 517 ALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKS----FENEGDRE 570
L ++H C IVH D+KP NVL+ + K++DFG+A KL + +S + G
Sbjct: 454 GLEYLHYGCKTRIVHFDIKPQNVLLDDNLSPKVSDFGLA-KLCEKKESVMSLMDTRGTIG 512
Query: 571 YIAPEIIRD--GIYDFRADIFSLGLMMIEI 598
YIAPE+I G ++D++S G+++ E+
Sbjct: 513 YIAPEMISRVYGSVSHKSDVYSYGMLVFEM 542
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 80.5 bits (197), Expect = 8e-15
Identities = 53/213 (24%), Positives = 111/213 (51%), Gaps = 17/213 (7%)
Query: 395 KFSNVSIMGKGQFSTVYQV---TFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDS 451
+F + ++G+G F V+ V T P+ G YA+K ++ +R+ ++ ++ +
Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVN 131
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
+IV+ ++ +G Y++ +F G++ + + V+ ++ ++ + +
Sbjct: 132 -------HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFY-----L 179
Query: 512 VEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDRE 570
E+ LAL +H IV+ DLKP N+L+ G++KL DFG++ + + E K++ G E
Sbjct: 180 AELALALDHLHQ-LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVE 238
Query: 571 YIAPEIIRDGIYDFRADIFSLGLMMIEIAANVI 603
Y+APE++ + AD +S G++M E+ +
Sbjct: 239 YMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTL 271
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 80.5 bits (197), Expect = 8e-15
Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 12/206 (5%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++G+G ++ V V +T YA+K V+ N ++I+ + T + V
Sbjct: 245 FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDD----EDIDWVQT-EKHVFEQ 299
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++V S + + + + E+ G+L +Q +Q++L + EI
Sbjct: 300 ASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQ-----RQRKLPEEHARFYSAEIS 354
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDREYIAP 574
LAL ++H+ I++ DLK NVL+ EG++KL D+GM + L D + G YIAP
Sbjct: 355 LALNYLHER-GIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAP 413
Query: 575 EIIRDGIYDFRADIFSLGLMMIEIAA 600
EI+R Y F D ++LG++M E+ A
Sbjct: 414 EILRGEDYGFSVDWWALGVLMFEMMA 439
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 80.5 bits (197), Expect = 8e-15
Identities = 63/211 (29%), Positives = 111/211 (51%), Gaps = 22/211 (10%)
Query: 394 TKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSV 452
T+FS ++G+G F VY+ E AIK + + I +EI++LS +
Sbjct: 340 TRFSQFELIGRGSFGDVYKAFDTELNKDVAIKVIDLEESEDEIEDIQKEISVLSQCRCP- 398
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
YI E+ S+ H+ +I+ E+ G++ +Q L++ I I
Sbjct: 399 --------YITEYYGSYLHQTKLWIIMEYMAGGSVADLLQPG-----NPLDEISIACITR 445
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP---IEDKSFENEGDR 569
++ A+ ++H I H D+K AN+L++ G++K+ADFG++ +L K+F G
Sbjct: 446 DLLHAVEYLHAEGKI-HRDIKAANILLSENGDVKVADFGVSAQLTRTISRRKTF--VGTP 502
Query: 570 EYIAPEIIRDGI-YDFRADIFSLGLMMIEIA 599
++APE+I++ Y+ +ADI+SLG+ MIE+A
Sbjct: 503 FWMAPEVIQNSEGYNEKADIWSLGITMIEMA 533
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 80.5 bits (197), Expect = 8e-15
Identities = 61/206 (29%), Positives = 104/206 (49%), Gaps = 12/206 (5%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++G+G ++ V V T YA+K ++ K T+ ++I+ + T + V
Sbjct: 261 FELIRVIGRGSYAKVLMVELRRTRRIYAMKVIK--KALVTDD--EDIDWVQT-EKHVFET 315
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++V S + + + EF G+L +Q +Q+RL + EI
Sbjct: 316 ASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQ-----RQRRLPEEHARFYAAEIS 370
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDREYIAP 574
LAL F+H+ I++ DLK NVL+ EG++KL D+GM + + D + G YIAP
Sbjct: 371 LALNFLHEK-GIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAP 429
Query: 575 EIIRDGIYDFRADIFSLGLMMIEIAA 600
EI+R Y F D ++LG+++ E+ A
Sbjct: 430 EILRGEDYGFSVDWWALGVLLYEMLA 455
>7292829 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kinase
MKK7/JNKK2
Length = 492
Score = 80.5 bits (197), Expect = 8e-15
Identities = 66/281 (23%), Positives = 125/281 (43%), Gaps = 28/281 (9%)
Query: 334 FSPSPSKTNLQTPTKTSFDIGPDSLAIMTK--LRNDPTHLQPPEKQRSINASIMKNPDFH 391
++P ++ + TPT GP T+ + PT PP + + I+
Sbjct: 123 YTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGK 182
Query: 392 LTTK----------FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQ 440
L ++ +G G V ++ + A+K +R T + N RIL
Sbjct: 183 LNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILM 242
Query: 441 EINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQ 500
+++++ D +YIV+ + + +I E + + + ++
Sbjct: 243 DLDVVLKSHDC--------KYIVKCLGCFVRDPDVWICMEL-----MSMCFDKLLKLSKK 289
Query: 501 RLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIED 560
+ + + K+ V AL ++ D ++H D+KP+N+LI GN+KL DFG++ +L
Sbjct: 290 PVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSK 349
Query: 561 KSFENEGDREYIAPEII--RDGIYDFRADIFSLGLMMIEIA 599
+ + G Y+APE I + YD RAD++SLG+ ++E+A
Sbjct: 350 ANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELA 390
>Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 80.5 bits (197), Expect = 8e-15
Identities = 57/203 (28%), Positives = 105/203 (51%), Gaps = 12/203 (5%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+GKG + V++V + G K A+K + P H+ I E N+L + D + + Y
Sbjct: 27 IGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIEAEYNILKALSD---HPNVVRFY 82
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
+ F + +++ E C G++ ++ + + +R+ + I I+ E + L+ +
Sbjct: 83 GIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGF-LKRGERMSEPLIAYILHEALMGLQHL 141
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYIAPEIIR-- 578
H++ +I H D+K N+L+T EG +KL DFG++ +L + + G ++APE+I
Sbjct: 142 HNNKTI-HRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPEVIACE 200
Query: 579 ---DGIYDFRADIFSLGLMMIEI 598
D YD R D +SLG+ IE+
Sbjct: 201 QQLDTTYDARCDTWSLGITAIEL 223
>Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 80.5 bits (197), Expect = 8e-15
Identities = 57/203 (28%), Positives = 105/203 (51%), Gaps = 12/203 (5%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+GKG + V++V + G K A+K + P H+ I E N+L + D + + Y
Sbjct: 27 IGKGTYGKVFKVLNKKNGQKAAVKILDPI-HDIDEEIEAEYNILKALSD---HPNVVRFY 82
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
+ F + +++ E C G++ ++ + + +R+ + I I+ E + L+ +
Sbjct: 83 GIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGF-LKRGERMSEPLIAYILHEALMGLQHL 141
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYIAPEIIR-- 578
H++ +I H D+K N+L+T EG +KL DFG++ +L + + G ++APE+I
Sbjct: 142 HNNKTI-HRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPEVIACE 200
Query: 579 ---DGIYDFRADIFSLGLMMIEI 598
D YD R D +SLG+ IE+
Sbjct: 201 QQLDTTYDARCDTWSLGITAIEL 223
>YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 506
Score = 80.1 bits (196), Expect = 1e-14
Identities = 53/213 (24%), Positives = 108/213 (49%), Gaps = 16/213 (7%)
Query: 391 HLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP--TKHNFTNRILQEINMLSTI 448
HL + + + I+G+G +V + +A+K++ T + +I +E+
Sbjct: 209 HLKDEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQF---- 264
Query: 449 QDSVTNDTEGKEYIVEFISSWSHK--GSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
N + +YIV++ ++ + S YI E+ +L+A ++++ + R+ +
Sbjct: 265 -----NKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEA-TYKNLLKRGGRISERV 318
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
I KI + L ++H+ ++H D+KP N+L+ +G +KL DFG++ + + +
Sbjct: 319 IGKIAESVLRGLSYLHER-KVIHRDIKPQNILLNEKGEIKLCDFGVSGE-AVNSLAMTFT 376
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
G Y+APE I+ Y D++SLGL ++E+A
Sbjct: 377 GTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVA 409
>SPAC1D4.13 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 340
Score = 80.1 bits (196), Expect = 1e-14
Identities = 47/139 (33%), Positives = 80/139 (56%), Gaps = 6/139 (4%)
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
YIV F ++ +K + + E+ + G+LDA ++E L KII + L +
Sbjct: 121 YIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILG-----KIINSMVKGLIY 175
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG 580
+++ I+H DLKP+NV++ G +KL DFG++ +L + + G Y++PE IR G
Sbjct: 176 LYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGEL-VNSVAQTFVGTSTYMSPERIRGG 234
Query: 581 IYDFRADIFSLGLMMIEIA 599
Y ++DI+SLG+ +IE+A
Sbjct: 235 KYTVKSDIWSLGISIIELA 253
>At3g07070 [T] KOG1187 Serine/threonine protein kinase
Length = 414
Score = 80.1 bits (196), Expect = 1e-14
Identities = 57/213 (26%), Positives = 104/213 (48%), Gaps = 19/213 (8%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T F ++G+G F VY+ +TG+ A+K + + E+ MLS +
Sbjct: 76 TKNFRQECLIGEGGFGRVYKGKLEKTGMIVAVKQLDRNGLQGNKEFIVEVLMLSLLHH-- 133
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDW--RIWKI 510
+++V I + ++ E+ G+L+ + + + Q DW RI +I
Sbjct: 134 -------KHLVNLIGYCADGDQRLLVYEYMSRGSLEDHLLD--LTPDQIPLDWDTRI-RI 183
Query: 511 IVEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-- 566
+ + L ++HD + +++ DLK AN+L+ E N KL+DFG+A P+ DK +
Sbjct: 184 ALGAAMGLEYLHDKANPPVIYRDLKAANILLDGEFNAKLSDFGLAKLGPVGDKQHVSSRV 243
Query: 567 -GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G Y APE R G ++D++S G++++E+
Sbjct: 244 MGTYGYCAPEYQRTGQLTTKSDVYSFGVVLLEL 276
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 79.7 bits (195), Expect = 1e-14
Identities = 66/234 (28%), Positives = 118/234 (50%), Gaps = 27/234 (11%)
Query: 372 QPPEKQRSINA----SIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV 427
QPP + + S+ K P+ F + +G+G + +V++ E+G AIK V
Sbjct: 3 QPPAPKSKLKKLSEDSLTKQPE----EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV 58
Query: 428 RPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNL 487
P + + I++EI+++ Y+V++ S+ +I+ E+C G++
Sbjct: 59 -PVESDL-QEIIKEISIMQQCDSP---------YVVKYYGSYFKNTDLWIVMEYCGAGSV 107
Query: 488 DAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKL 547
I+ + + +ED I I+ L ++H I H D+K N+L+ EG+ KL
Sbjct: 108 SDIIR---LRNKTLIED-EIATILKSTLKGLEYLHFMRKI-HRDIKAGNILLNTEGHAKL 162
Query: 548 ADFGMATKLPIEDKSFENE--GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
ADFG+A +L + + N G ++APE+I++ Y+ ADI+SLG+ IE+A
Sbjct: 163 ADFGVAGQL-TDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMA 215
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 79.7 bits (195), Expect = 1e-14
Identities = 66/234 (28%), Positives = 118/234 (50%), Gaps = 27/234 (11%)
Query: 372 QPPEKQRSINA----SIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV 427
QPP + + S+ K P+ F + +G+G + +V++ E+G AIK V
Sbjct: 3 QPPAPKSKLKKLSEDSLTKQPE----EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV 58
Query: 428 RPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNL 487
P + + I++EI+++ Y+V++ S+ +I+ E+C G++
Sbjct: 59 -PVESDL-QEIIKEISIMQQCDSP---------YVVKYYGSYFKNTDLWIVMEYCGAGSV 107
Query: 488 DAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKL 547
I+ + + +ED I I+ L ++H I H D+K N+L+ EG+ KL
Sbjct: 108 SDIIR---LRNKTLIED-EIATILKSTLKGLEYLHFMRKI-HRDIKAGNILLNTEGHAKL 162
Query: 548 ADFGMATKLPIEDKSFENE--GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
ADFG+A +L + + N G ++APE+I++ Y+ ADI+SLG+ IE+A
Sbjct: 163 ADFGVAGQL-TDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMA 215
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 79.3 bits (194), Expect = 2e-14
Identities = 60/200 (30%), Positives = 103/200 (51%), Gaps = 22/200 (11%)
Query: 402 MGKGQFSTVYQV-TFPETGLKYAIKSVRPTKHNFTN--RILQEINMLSTIQDSVTNDTEG 458
+G G ++TVY+ +T AIK V N + +L EI +L I+
Sbjct: 63 LGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHP------- 115
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVE-ICLA 517
+IV+ + Y++ EFC G+L FI I + ++ ++ ++ + A
Sbjct: 116 --HIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPE------KVARVFMQQLASA 167
Query: 518 LRFIHDSCSIVHLDLKPANVLITF--EGNLKLADFGMATKLPIEDKSFENEGDREYIAPE 575
L+F+H+ +I HLDLKP N+L++ + +LKLADFG A + D+ G Y+APE
Sbjct: 168 LQFLHER-NISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPE 226
Query: 576 IIRDGIYDFRADIFSLGLMM 595
++ YD R D++S+G+++
Sbjct: 227 MVCQRQYDARVDLWSMGVIL 246
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 79.3 bits (194), Expect = 2e-14
Identities = 60/220 (27%), Positives = 106/220 (47%), Gaps = 25/220 (11%)
Query: 388 PDFHLTTKFSNVSIMGKGQFSTVYQV---TFPETGLKYAIKSVRPTKHNFTNRILQEINM 444
PD F + ++G+G + V+QV T + G YA+K + K T + L+
Sbjct: 15 PDDVAPKDFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARD 74
Query: 445 LSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED 504
I +++ + ++ + ++ Y++ EF G L ++ R D
Sbjct: 75 ERKILETINSP-----FLCDLHYAFQTNEKLYLVLEFLHGGELYTLLE--------RKSD 121
Query: 505 W-----RIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMAT-KLPI 558
W R + + EI LA+ +H IV+ DLKP NV++ G++ L DFG+ KL
Sbjct: 122 WPEEYARFY--LSEIILAIEHLHGH-DIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKK 178
Query: 559 EDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+K+ G EY+APE+IR +D D+++LG++M ++
Sbjct: 179 GEKTLTFCGTHEYMAPEMIRKVGHDHAVDVWALGILMYDM 218
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 79.3 bits (194), Expect = 2e-14
Identities = 62/204 (30%), Positives = 97/204 (47%), Gaps = 16/204 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+GKGQ V T TG K AIK V K + +LQ++ I + + +
Sbjct: 53 LGKGQTGLVKTGTHCITGRKVAIKIVN--KEKLSESVLQKVEREIAIMKLIEHP-----H 105
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
++ + +K Y++ E G L ++ ++ RL K +I AL F
Sbjct: 106 VLHLYDVYENKKYLYLLLEHVSGGELFDYL-----VRKGRLMSKEARKFFRQIISALDFC 160
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-GDREYIAPEIIRDG 580
H + +I H DLKP N+L+ N+K+ADFGMA+ L +E E G Y PE+IR
Sbjct: 161 H-AHNICHRDLKPENLLLDERNNIKVADFGMAS-LQVEGSMLETSCGSPHYACPEVIRGE 218
Query: 581 IYDFR-ADIFSLGLMMIEIAANVI 603
YD R AD++S G+++ + +
Sbjct: 219 KYDGRKADVWSCGVILYALLVGAL 242
>At1g14370 [T] KOG1187 Serine/threonine protein kinase
Length = 426
Score = 79.3 bits (194), Expect = 2e-14
Identities = 93/407 (22%), Positives = 173/407 (41%), Gaps = 72/407 (17%)
Query: 330 ESSIFSP--SPSKTNLQTPTKTSFDIGPDSLAI-----------MTKLRNDPTHLQPPEK 376
++S SP + + + + +KTS GP L+ + LR + L P
Sbjct: 12 DNSNHSPHANSASSGSKVSSKTSRSTGPSGLSTTSYSTDSSFGPLPTLRTEGEILSSPNL 71
Query: 377 QRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQ---------VTFPETGLKYAIKSV 427
++ + +KN T F +++G+G F V++ + P +G+ A+K +
Sbjct: 72 -KAFTFNELKNA----TKNFRQDNLLGEGGFGCVFKGWIDQTSLTASRPGSGIVVAVKQL 126
Query: 428 RPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNL 487
+P L E+N L + +V + + + ++ EF G+L
Sbjct: 127 KPEGFQGHKEWLTEVNYLGQLSHP---------NLVLLVGYCAEGENRLLVYEFMPKGSL 177
Query: 488 DAFIQEHVIAKQQRLEDWRI-WKIIVEICLALRFIHDSCS-IVHLDLKPANVLITFEGNL 545
+ H+ + + W I K+ V L F+H++ S +++ D K AN+L+ + N
Sbjct: 178 E----NHLFRRGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRDFKAANILLDADFNA 233
Query: 546 KLADFGMATKLPIEDKSFENE---GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANV 602
KL+DFG+A P D + + G Y APE + G ++D++S G++++E+ +
Sbjct: 234 KLSDFGLAKAGPTGDNTHVSTKVIGTHGYAAPEYVATGRLTAKSDVYSFGVVLLELISG- 292
Query: 603 ILPDNGSAWHKLRSGDLSDAGRLSSAEIHSSSLFSNKKDHTNITDITTHETKIPAWVPK- 661
R+ D S+ G S ++ +K+ I D TK+ P+
Sbjct: 293 -----------RRAMDNSNGGNEYSLVDWATPYLGDKRKLFRIMD-----TKLGGQYPQK 336
Query: 662 --FLLDGISLERTIRWMIEPDYRDRPSASDLLRTEELEYVELTRKTG 706
F ++L+ + PD + RP S++L T LE +E K G
Sbjct: 337 GAFTAANLALQ-----CLNPDAKLRPKMSEVLVT--LEQLESVAKPG 376
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 79.0 bits (193), Expect = 2e-14
Identities = 55/208 (26%), Positives = 99/208 (47%), Gaps = 20/208 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP---TKHNFTNRILQEINMLSTIQDSV 452
F + +G G F V+ + G YA+K+++ K E MLS +
Sbjct: 88 FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHP- 146
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+I+ ++ +++ ++ E G L + ++ K QR +
Sbjct: 147 --------FIIRMWGTFQDSQQVFMVMDYIEGGELFSLLR-----KSQRFPNPVAKFYAA 193
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYI 572
E+CLAL ++H S I++ DLKP N+L+ G++K+ DFG A +P D ++ G +YI
Sbjct: 194 EVCLALEYLH-SKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP--DVTYTLCGTPDYI 250
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEIAA 600
APE++ Y+ D +S G+++ E+ A
Sbjct: 251 APEVVSTKPYNKSVDWWSFGVLIYEMLA 278
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 79.0 bits (193), Expect = 2e-14
Identities = 59/200 (29%), Positives = 104/200 (51%), Gaps = 20/200 (10%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTK--HNFTNRILQEINMLSTIQDSVTNDTEGK 459
+GKG F VY+ + G A+K V+ +K + + I EI++L +
Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHP-------- 66
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALR 519
IV++ S+ S I+ E+CENG+L + + ++ + + ++ L
Sbjct: 67 -NIVKYRGSYQTNDSLCIILEYCENGSLRSICKNF-----GKIPENLVALYTFQVLQGLL 120
Query: 520 FIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYIAPEIIR 578
++H+ ++H D+K AN+L T +G +KLADFG+ATK+ +ED S G ++APE+I
Sbjct: 121 YLHNQ-GVIHRDIKGANILTTKDGTIKLADFGVATKINALEDHSV--VGSPYWMAPEVIE 177
Query: 579 DGIYDFRADIFSLGLMMIEI 598
+DI+S+G +IE+
Sbjct: 178 LVGATTASDIWSVGCTVIEL 197
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 79.0 bits (193), Expect = 2e-14
Identities = 60/209 (28%), Positives = 102/209 (48%), Gaps = 19/209 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP---TKHNFTNRILQEINMLSTIQDSV 452
F+ + ++GKG F VY V +T YA+K + + L E N+L V
Sbjct: 302 FTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNIL------V 355
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+ +IV S+ Y++T++ G L +Q +QR + + I
Sbjct: 356 RTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFY-----IA 410
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDRE 570
E+ LAL +H I++ DLKP N+L+ +G++ L DFG+ +K + + N G E
Sbjct: 411 ELVLALEHLHKH-DIIYRDLKPENILLDADGHIALCDFGL-SKANLSANATTNTFCGTTE 468
Query: 571 YIAPEI-IRDGIYDFRADIFSLGLMMIEI 598
Y+APE+ + D Y + D +SLG+++ E+
Sbjct: 469 YLAPEVLLEDKGYTKQVDFWSLGVLVFEM 497
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 79.0 bits (193), Expect = 2e-14
Identities = 51/214 (23%), Positives = 113/214 (51%), Gaps = 17/214 (7%)
Query: 394 TKFSNVSIMGKGQFSTVY---QVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQD 450
++F + ++G+G F V+ +++ + YA+K ++ +R+ ++ ++
Sbjct: 66 SQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEV 125
Query: 451 SVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKI 510
+ +IV+ ++ +G Y++ +F G+L + + V+ ++ ++ +
Sbjct: 126 N-------HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY----- 173
Query: 511 IVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDR 569
+ E+ LAL +H S I++ DLKP N+L+ EG++KL DFG++ + + E K++ G
Sbjct: 174 LAELALALDHLH-SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTV 232
Query: 570 EYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVI 603
EY+APE++ + AD +S G++M E+ +
Sbjct: 233 EYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTL 266
Score = 55.1 bits (131), Expect = 4e-07
Identities = 46/199 (23%), Positives = 89/199 (44%), Gaps = 23/199 (11%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+G G +S + T +++A+K + +K + T +EI +L
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPT----EEIEILLRYGQHPN-------- 475
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
I+ + Y++TE + G L I +Q+ + ++ I + ++
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGEL-----LDKILRQKFFSEREASAVLFTITKTVEYL 530
Query: 522 HDSCSIVHLDLKPANVLITFEG----NLKLADFGMATKLPIEDKSFENEG-DREYIAPEI 576
H +VH DLKP+N+L E ++++ DFG A +L E+ ++APE+
Sbjct: 531 HAQ-GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEV 589
Query: 577 IRDGIYDFRADIFSLGLMM 595
++ YD DI+SLG+++
Sbjct: 590 LKRQGYDAACDIWSLGVLL 608
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 79.0 bits (193), Expect = 2e-14
Identities = 54/225 (24%), Positives = 107/225 (47%), Gaps = 17/225 (7%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTN 454
K+ ++G+G S V + TG ++A+K + T + L+E+ + + +
Sbjct: 23 KYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILR 82
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
G +I+ I S+ +++ + G L ++ E V ++ E I + ++E
Sbjct: 83 QVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEK--ETRSIMRSLLE- 139
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAP 574
A+ F+H + +IVH DLKP N+L+ ++L+DFG + L +K E G Y+AP
Sbjct: 140 --AVSFLHAN-NIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAP 196
Query: 575 EIIRDGI------YDFRADIFSLGLMMIEIAANVILPDNGSAWHK 613
EI++ + Y D+++ G+++ +L + WH+
Sbjct: 197 EILKCSMDETHPGYGKEVDLWACGVILF-----TLLAGSPPFWHR 236
>Hs21735544 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kinase
MKK7/JNKK2
Length = 419
Score = 79.0 bits (193), Expect = 2e-14
Identities = 57/208 (27%), Positives = 104/208 (49%), Gaps = 19/208 (9%)
Query: 398 NVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTN-RILQEINMLSTIQDSVTNDT 456
N+ MG G V+++ F +TG A+K +R + + N RIL +++++ D
Sbjct: 122 NLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDC----- 176
Query: 457 EGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICL 516
YIV+ ++ +I E G +++ + Q + + + K+ V I
Sbjct: 177 ---PYIVQCFGTFITNTDVFIAMELM--GTCAEKLKKRM---QGPIPERILGKMTVAIVK 228
Query: 517 ALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEI 576
AL ++ + ++H D+KP+N+L+ G +KL DFG++ +L + G Y+APE
Sbjct: 229 ALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPER 288
Query: 577 I-----RDGIYDFRADIFSLGLMMIEIA 599
I YD RAD++SLG+ ++E+A
Sbjct: 289 IDPPDPTKPDYDIRADVWSLGISLVELA 316
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 79.0 bits (193), Expect = 2e-14
Identities = 64/207 (30%), Positives = 104/207 (49%), Gaps = 20/207 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK-HNFTNRILQEINMLSTIQDSVTN 454
F+ + +GKG F V++ T AIK + + + I QEI +LS
Sbjct: 36 FTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSP--- 92
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGN-LDAFIQEHVIAKQQRLEDWRIWKIIVE 513
Y+ ++ S+ +I+ E+ G+ LD + + L++ +I I+ E
Sbjct: 93 ------YVTKYYGSYLKDTKLWIIMEYLGGGSALD-------LLEPGPLDETQIATILRE 139
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYI 572
I L ++H I H D+K ANVL++ G +KLADFG+A +L + K G ++
Sbjct: 140 ILKGLDYLHSEKKI-HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWM 198
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEIA 599
APE+I+ YD +ADI+SLG+ IE+A
Sbjct: 199 APEVIKQSAYDSKADIWSLGITAIELA 225
>CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1228
Score = 79.0 bits (193), Expect = 2e-14
Identities = 64/207 (30%), Positives = 108/207 (51%), Gaps = 24/207 (11%)
Query: 402 MGKGQFSTVYQ-VTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G G F V + V+ + L A KS+ + L EI +LS + +G
Sbjct: 40 LGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVEIEILS--------ECKGHP 91
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQE--HVIAKQQRLEDWRIWKIIVEICLAL 518
++ S++ + ++ EFC G +D I E HV+ + Q I I +C AL
Sbjct: 92 VMLGLYSTYFFENKLTMLLEFCGGGAVDNIIVELGHVLKEDQ------IRYIGYYVCDAL 145
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIE-DKSFENEGDREYIAPEII 577
+++H S +++H DLK N+L+T +G ++LADFG++ KL E +K G ++APE++
Sbjct: 146 KWLH-SQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMAPEVM 204
Query: 578 -----RDGIYDFRADIFSLGLMMIEIA 599
+D YD +DI+S G+ +IE+A
Sbjct: 205 ACETFKDQPYDCISDIWSFGITLIEMA 231
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 79.0 bits (193), Expect = 2e-14
Identities = 62/219 (28%), Positives = 106/219 (48%), Gaps = 22/219 (10%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLST-IQDSVTNDTEGKE 460
+G GQF + + TG + A KS+ +R++ + +M S ++ ++ G
Sbjct: 50 LGWGQFGVIRVCSDKLTGERLACKSISK------DRLVTQDDMKSIKLEIAIMAKLAGHP 103
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
+V + + K S +++ E C G L H + K R + R + + ++F
Sbjct: 104 NVVNLKAVYEEKDSVHLVMELCAGGELF-----HKLEKYGRYSEVRARVLFKHLMQVVKF 158
Query: 521 IHDSCSIVHLDLKPANVLITFEGN---LKLADFGMATKLPIEDKSFENEGDREYIAPEII 577
HDS IVH DLKP N+L+ + +KLADFG+AT + +K G YIAPE++
Sbjct: 159 CHDS-GIVHRDLKPENILMATMSSSSPIKLADFGLATYIKPGEKLSGTVGSPFYIAPEVL 217
Query: 578 RDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRS 616
G Y+ AD++S G+++ ++L W K +S
Sbjct: 218 AGG-YNQAADVWSAGVILY-----ILLSGAPPFWGKTKS 250
>YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 508
Score = 78.6 bits (192), Expect = 3e-14
Identities = 54/213 (25%), Positives = 105/213 (48%), Gaps = 16/213 (7%)
Query: 391 HLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP--TKHNFTNRILQEINMLSTI 448
+L + + I+G+G +V + +A+K + T + +I +E+ +
Sbjct: 216 NLKDRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSF 275
Query: 449 QDSVTNDTEGKEYIVEFISSWS--HKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
Q EYIV + ++ S YI E+ +LDA I ++++ + R+ +
Sbjct: 276 QS---------EYIVRYYGMFTDDENSSIYIAMEYMGGRSLDA-IYKNLLERGGRISEKV 325
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
+ KI + L ++H+ ++H D+KP N+L+ G +KL DFG++ + + +
Sbjct: 326 LGKIAEAVLRGLSYLHEK-KVIHRDIKPQNILLNENGQVKLCDFGVSGE-AVNSLATTFT 383
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
G Y+APE I+ Y +D++SLGL ++E+A
Sbjct: 384 GTSFYMAPERIQGQPYSVTSDVWSLGLTILEVA 416
>YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 655
Score = 78.6 bits (192), Expect = 3e-14
Identities = 65/261 (24%), Positives = 123/261 (46%), Gaps = 39/261 (14%)
Query: 361 MTKLRNDPTHLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVY---QVTFPE 417
+ +L+N+ + K +++ + P F L K G+G VY ++ P+
Sbjct: 331 LLELKNNDDSNEIIMKMKTVAIDVNPRPYFQLVEK------AGQGASGAVYLSKRIKLPQ 384
Query: 418 --------------TGLKYAIKSVRPTKHNFTNRILQEINMLS-TIQDSVTNDTEGKEYI 462
G + AIK +R ++ I+ E+ +++ + Q+++ N E YI
Sbjct: 385 ENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEA--YI 442
Query: 463 VEFISSWSHKGSFYIMTEFCENGNL----DAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
++ W ++ E+ E G L DA + + L + ++ I+ E C L
Sbjct: 443 IDDEELW-------VIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGL 495
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIE-DKSFENEGDREYIAPEII 577
+F+H+ I+H D+K N+L+ +G +K+ DFG +L + K G ++APEI+
Sbjct: 496 KFLHNK-KIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIV 554
Query: 578 RDGIYDFRADIFSLGLMMIEI 598
YD + D++SLG+M+IE+
Sbjct: 555 NQKGYDEKVDVWSLGIMLIEM 575
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 78.6 bits (192), Expect = 3e-14
Identities = 57/205 (27%), Positives = 101/205 (48%), Gaps = 11/205 (5%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++GKG F VY V +T YA+K + + + + + D
Sbjct: 266 FVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAAD 325
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+ +IV S+ Y++T++ G L +Q+ V ++R + + I E+
Sbjct: 326 SP---FIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFY-----IAELL 377
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMA-TKLPIEDKSFENEGDREYIAP 574
LAL+ +H IV+ DLKP N+L+ +G++ L DFG++ L + + G +Y+AP
Sbjct: 378 LALQALHKR-GIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAP 436
Query: 575 EIIRDGI-YDFRADIFSLGLMMIEI 598
E+I D YD D +SLG+++ E+
Sbjct: 437 EVILDEAGYDMMVDFWSLGVLLYEM 461
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 78.6 bits (192), Expect = 3e-14
Identities = 66/272 (24%), Positives = 122/272 (44%), Gaps = 31/272 (11%)
Query: 328 DQESSIFSPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQRSINASIMKN 387
D +S SP+ + T TP PD+L T+ + + E + + +
Sbjct: 216 DVATSPISPTENNT---TP--------PDALTRNTEKQKKKPKMSDEEILEKLRSIVSVG 264
Query: 388 PDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLST 447
T+F + G+G TVY TG + AIK + + I+ EI ++
Sbjct: 265 DPKKKYTRFEKI---GQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRE 321
Query: 448 IQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI 507
++ IV ++ S+ +++ E+ G+L + E +++ +I
Sbjct: 322 NKNP---------NIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC------MDEGQI 366
Query: 508 WKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENE 566
+ E AL F+H + ++H D+K N+L+ +G++KL DFG ++ P + K
Sbjct: 367 AAVCRECLQALEFLHSN-QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMV 425
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G ++APE++ Y + DI+SLG+M IE+
Sbjct: 426 GTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEM 457
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 78.6 bits (192), Expect = 3e-14
Identities = 58/205 (28%), Positives = 101/205 (48%), Gaps = 14/205 (6%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDS-VTN 454
F + ++GKG F V ETG YA+K ++ + IL + ++ T+ + + +
Sbjct: 354 FEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKK------DVILLDDDVECTMTEKRILS 407
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
++ + + + + EF G+L IQ K +R ++ R EI
Sbjct: 408 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQ-----KSRRFDEARARFYAAEI 462
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-GDREYIA 573
AL F+HD I++ DLK NVL+ EG+ KLADFGM + + G +YIA
Sbjct: 463 ISALMFLHDK-GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIA 521
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEI 598
PEI+++ +Y D +++G+++ E+
Sbjct: 522 PEILQEMLYGPAVDWWAMGVLLYEM 546
>Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 438
Score = 78.6 bits (192), Expect = 3e-14
Identities = 58/203 (28%), Positives = 97/203 (47%), Gaps = 25/203 (12%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G G TVY+ +G A+K + +I+ E+ +L S
Sbjct: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSS--------- 222
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAF--IQEHVIAKQQRLEDWRIWKIIVEICLAL 518
YI+ F ++ + I TEF + G+LD + + EHV+ + I V + L
Sbjct: 223 YIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGR-----------IAVAVVKGL 271
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
++ S I+H D+KP+N+L+ G +KL DFG++T+L + + G Y+APE I
Sbjct: 272 TYLW-SLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQL-VNSIAKTYVGTNAYMAPERIS 329
Query: 579 DGIYDFRADIFSLGLMMIEIAAN 601
Y +D++SLG+ +EI N
Sbjct: 330 GEQYGIHSDVWSLGISFMEIQKN 352
>Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 467
Score = 78.6 bits (192), Expect = 3e-14
Identities = 58/203 (28%), Positives = 97/203 (47%), Gaps = 25/203 (12%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G G TVY+ +G A+K + +I+ E+ +L S
Sbjct: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSS--------- 222
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAF--IQEHVIAKQQRLEDWRIWKIIVEICLAL 518
YI+ F ++ + I TEF + G+LD + + EHV+ + I V + L
Sbjct: 223 YIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGR-----------IAVAVVKGL 271
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
++ S I+H D+KP+N+L+ G +KL DFG++T+L + + G Y+APE I
Sbjct: 272 TYLW-SLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQL-VNSIAKTYVGTNAYMAPERIS 329
Query: 579 DGIYDFRADIFSLGLMMIEIAAN 601
Y +D++SLG+ +EI N
Sbjct: 330 GEQYGIHSDVWSLGISFMEIQKN 352
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 78.6 bits (192), Expect = 3e-14
Identities = 59/225 (26%), Positives = 109/225 (48%), Gaps = 29/225 (12%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++ G + VY V ET ++A+K + T + +++ + +D +T
Sbjct: 358 FDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQ----TLMLRNQVDQVFAERDILT-- 411
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++V F S+ + ++ E+ E G+ A ++ A +E R++ + E
Sbjct: 412 MADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKS---AGTLPVELVRLY--VAETI 466
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMAT--------------KLPIEDK 561
LA+ ++H S IVH DLKP N+LIT G++KL DFG++ +E +
Sbjct: 467 LAIEYLH-SYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQ 525
Query: 562 SFENE---GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVI 603
F+++ G EYIAPE+I Y D ++LG+++ E ++
Sbjct: 526 QFQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIV 570
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 78.6 bits (192), Expect = 3e-14
Identities = 68/241 (28%), Positives = 110/241 (45%), Gaps = 30/241 (12%)
Query: 386 KNPDFHLTTK-FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRP---TKHNFTNRILQE 441
K P + T+ F I G G +S V + ETG YA+K + TK N T + E
Sbjct: 30 KAPQENFTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLE 89
Query: 442 INMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQR 501
+L ++ I++ ++ S Y+ E CE G L F Q I ++ R
Sbjct: 90 RIVLDQLEHPG---------IIKLYFTFQDTSSLYMALESCEGGEL--FDQ---ITRKGR 135
Query: 502 LEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFG--------MA 553
L + E+ AL +IH S ++H D+KP N+L+T +G++K+ADFG
Sbjct: 136 LSEDEARFYTAEVVDALEYIH-SMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQI 194
Query: 554 TKLP---IEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSA 610
T LP +DK+ G Y+ PE++ F D+++LG + ++ + + S
Sbjct: 195 TVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASE 254
Query: 611 W 611
W
Sbjct: 255 W 255
>At1g70740 [T] KOG1187 Serine/threonine protein kinase
Length = 381
Score = 78.6 bits (192), Expect = 3e-14
Identities = 62/220 (28%), Positives = 105/220 (47%), Gaps = 30/220 (13%)
Query: 389 DFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTI 448
DFH T K +G+G F V++ P+ G A+K + N + E +L+ +
Sbjct: 17 DFHPTHK------LGEGGFGPVFKGRLPD-GRDIAVKKLSQVSRQGKNEFVNEAKLLAKV 69
Query: 449 QDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLE--DWR 506
Q +V +H ++ E+ N +LD V+ K R DW+
Sbjct: 70 QH---------RNVVNLWGYCTHGDDKLLVYEYVVNESLDK-----VLFKSNRKSEIDWK 115
Query: 507 I-WKIIVEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSF 563
++II I L ++H+ I+H D+K N+L+ + K+ADFGMA +L ED +
Sbjct: 116 QRFEIITGIARGLLYLHEDAPNCIIHRDIKAGNILLDEKWVPKIADFGMA-RLYQEDVTH 174
Query: 564 ENE---GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAA 600
N G Y+APE + G+ +AD+FS G++++E+ +
Sbjct: 175 VNTRVAGTNGYMAPEYVMHGVLSVKADVFSFGVLVLELVS 214
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 78.6 bits (192), Expect = 3e-14
Identities = 59/203 (29%), Positives = 102/203 (50%), Gaps = 17/203 (8%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIK--SVRPTKHNFTNRILQEINMLSTIQDSVTNDTEG 458
++GKG + V V G +Y IK ++R QE +LS ++
Sbjct: 11 VVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHP------- 63
Query: 459 KEYIVEFISSWSH-KGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
IV + SW G YI+ FCE G+L ++E K Q L + ++ + V+I +A
Sbjct: 64 --NIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQ---KGQLLPENQVVEWFVQIAMA 118
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIE-DKSFENEGDREYIAPEI 576
L+++H+ I+H DLK NV +T +K+ D G+A L D + G Y++PE+
Sbjct: 119 LQYLHEK-HILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPEL 177
Query: 577 IRDGIYDFRADIFSLGLMMIEIA 599
+ Y++++D+++LG + E+A
Sbjct: 178 FSNKPYNYKSDVWALGCCVYEMA 200
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 78.2 bits (191), Expect = 4e-14
Identities = 60/214 (28%), Positives = 108/214 (50%), Gaps = 31/214 (14%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR--PTKHNFTNRILQEINMLSTIQDSV 452
++ ++ ++G+G F +V++ E+ A+K V TK + QEIN L +
Sbjct: 5 QYRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIET-LTQEINFLIDL---- 59
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGN------LDAFIQEHVIAKQQRLEDWR 506
N +Y F+ + +I E+C+ G+ L E VIA+ R
Sbjct: 60 -NSVHITKYYASFVDGFR----LWITMEYCDGGSCLDLLKLSGTFSERVIAEVMR----- 109
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP-IEDKSFEN 565
++ AL ++H + H D+K AN+L +G +KLADFG++ +L + DK+ +
Sbjct: 110 ------QVLEALVYLHGQGKM-HRDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDF 162
Query: 566 EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
G ++APE+++ Y+++ADI+SLG+ E+A
Sbjct: 163 VGTPFWMAPEVVKQTGYNYKADIWSLGITAYELA 196
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 78.2 bits (191), Expect = 4e-14
Identities = 69/236 (29%), Positives = 112/236 (47%), Gaps = 23/236 (9%)
Query: 373 PPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKH 432
P I+ S +++P F V ++G G + VY+ +TG AIK + T+
Sbjct: 6 PARSLDDIDLSALRDP----AGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED 61
Query: 433 NFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQ 492
I QEINML T +I + S + +++ EFC G++ ++
Sbjct: 62 E-EEEIKQEINMLKKYSHHRNIATYYGAFIKK--SPPGNDDQLWLVMEFCGAGSVTDLVK 118
Query: 493 EHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGM 552
K L++ I I EI L +H + ++H D+K NVL+T +KL DFG+
Sbjct: 119 N---TKGNALKEDCIAYICREILRGLAHLH-AHKVIHRDIKGQNVLLTENAEVKLVDFGV 174
Query: 553 ATKLPIEDKSFENE----GDREYIAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
+ +L D++ G ++APE+I D YD+R+DI+SLG+ IE+A
Sbjct: 175 SAQL---DRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMA 227
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 78.2 bits (191), Expect = 4e-14
Identities = 52/211 (24%), Positives = 113/211 (52%), Gaps = 21/211 (9%)
Query: 394 TKFSNVSIMGKGQFSTVY---QVTFPETGLKYAIKSVRPTKHNFTNRILQEI--NMLSTI 448
++F + ++G+G + V+ +V + G YA+K ++ +R+ ++ ++L+ +
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV 116
Query: 449 QDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIW 508
+IV+ ++ +G Y++ +F G+L + + V+ ++ ++ +
Sbjct: 117 NHP---------FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFY--- 164
Query: 509 KIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDK-SFENEG 567
+ E+ LAL +H S I++ DLKP N+L+ EG++K+ DFG++ + DK ++ G
Sbjct: 165 --LAELALALDHLH-SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCG 221
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
EY+APE++ + AD +S G++M E+
Sbjct: 222 TIEYMAPEVVNRRGHTQSADWWSFGVLMFEM 252
Score = 54.7 bits (130), Expect = 5e-07
Identities = 51/227 (22%), Positives = 101/227 (44%), Gaps = 27/227 (11%)
Query: 389 DFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTI 448
+ H T + +G G +S + T +YA+K + +K + + +EI +L
Sbjct: 408 NIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPS----EEIEILLRY 463
Query: 449 QDSVTNDTEGKEYIVEFISSWSHKGSF-YIMTEFCENGNL-DAFIQEHVIAKQQRLEDWR 506
G+ + + G F Y++ E G L D +++ ++++ +
Sbjct: 464 ---------GQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASD--- 511
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEG----NLKLADFGMATKLPIEDKS 562
++ I + ++H S +VH DLKP+N+L E ++++ DFG A +L +
Sbjct: 512 ---VLCTITKTMDYLH-SQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGL 567
Query: 563 FENEG-DREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNG 608
++APE+++ YD DI+SLG+++ + A NG
Sbjct: 568 LMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANG 614
>At3g24540 [T] KOG1187 Serine/threonine protein kinase
Length = 509
Score = 78.2 bits (191), Expect = 4e-14
Identities = 56/212 (26%), Positives = 103/212 (48%), Gaps = 21/212 (9%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T KFS +++G+G F VY+ G + A+K ++ E+N++S I
Sbjct: 176 TNKFSEANLLGEGGFGFVYKGIL-NNGNEVAVKQLKVGSAQGEKEFQAEVNIISQIHH-- 232
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
+V + ++ EF N L+ H+ K + +W + KI
Sbjct: 233 -------RNLVSLVGYCIAGAQRLLVYEFVPNNTLEF----HLHGKGRPTMEWSLRLKIA 281
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--- 566
V L ++H++C+ I+H D+K AN+LI F+ K+ADFG+A K+ ++ + +
Sbjct: 282 VSSSKGLSYLHENCNPKIIHRDIKAANILIDFKFEAKVADFGLA-KIALDTNTHVSTRVM 340
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G Y+APE G ++D++S G++++E+
Sbjct: 341 GTFGYLAPEYAASGKLTEKSDVYSFGVVLLEL 372
>Hs21735542 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kinase
MKK7/JNKK2
Length = 462
Score = 77.8 bits (190), Expect = 5e-14
Identities = 62/238 (26%), Positives = 110/238 (46%), Gaps = 28/238 (11%)
Query: 368 PTHLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV 427
P LQP + A I N+ MG G V+++ F +TG A+K +
Sbjct: 144 PGTLQPSLSSQRYQAEI---------NDLENLGEMGSGTCGQVWKMRFRKTGHVIAVKQM 194
Query: 428 RPTKHNFTN-RILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGN 486
R + + N RIL +++++ D YIV+ ++ +I E G
Sbjct: 195 RRSGNKEENKRILMDLDVVLKSHDC--------PYIVQCFGTFITNTDVFIAMELM--GT 244
Query: 487 LDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLK 546
+++ + Q + + + K+ V I AL ++ + ++H D+KP+N+L+ G +K
Sbjct: 245 CAEKLKKRM---QGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIK 301
Query: 547 LADFGMATKLPIEDKSFENEGDREYIAPEII-----RDGIYDFRADIFSLGLMMIEIA 599
DFG++ +L + G Y+APE I YD RAD++SLG+ ++E+A
Sbjct: 302 FCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELA 359
>Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 448
Score = 77.8 bits (190), Expect = 5e-14
Identities = 57/201 (28%), Positives = 97/201 (47%), Gaps = 25/201 (12%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G G TVY+ +G A+K + +I+ E+ +L S
Sbjct: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSS--------- 222
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAF--IQEHVIAKQQRLEDWRIWKIIVEICLAL 518
YI+ F ++ + I TEF + G+LD + + EHV+ + I V + L
Sbjct: 223 YIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGR-----------IAVAVVKGL 271
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
++ S I+H D+KP+N+L+ G +KL DFG++T+L + + G Y+APE I
Sbjct: 272 TYLW-SLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQL-VNSIAKTYVGTNAYMAPERIS 329
Query: 579 DGIYDFRADIFSLGLMMIEIA 599
Y +D++SLG+ +E+A
Sbjct: 330 GEQYGIHSDVWSLGISFMELA 350
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 77.8 bits (190), Expect = 5e-14
Identities = 57/208 (27%), Positives = 102/208 (48%), Gaps = 20/208 (9%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQEINMLSTIQDS 451
+F + +G G F V V ETG YA+K + + K IL E +L I
Sbjct: 43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 102
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
++V+ S+ Y++ E+ G + + +Q + R +
Sbjct: 103 ---------FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQ-----RVGRFSEPHACFYA 148
Query: 512 VEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREY 571
++ LA++++H S ++H DLKP N+LI +G L++ DFG A + ++ +++ G EY
Sbjct: 149 AQVVLAVQYLH-SLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR--VKGRTWTLCGTPEY 205
Query: 572 IAPEIIRDGIYDFRADIFSLGLMMIEIA 599
+APEII Y+ D ++LG+++ E+A
Sbjct: 206 LAPEIILSKGYNKAVDWWALGVLIYEMA 233
>CE07399 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 343
Score = 77.8 bits (190), Expect = 5e-14
Identities = 55/202 (27%), Positives = 105/202 (51%), Gaps = 14/202 (6%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+GKG + V ++ ++G+ A+K ++ + ++ + + Q +N L + S +
Sbjct: 56 LGKGGYGIVEKMQHRQSGIIMAVKRIKSSINDQSQK--QMLNELDACRRS-----DCCPQ 108
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
+V F + +G +I E + +LD F + H + + + I K+ + + L F+
Sbjct: 109 MVRFYGAMFREGDVWICMEVMDT-SLDKFYR-HAYKIGKHIPEPFIGKMALSVIEGLNFM 166
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG- 580
+ +++H D+KP+N+L+ G +K+ DFG++ L G + Y+ PE I DG
Sbjct: 167 KEQLNLIHRDVKPSNILLNRHGQVKICDFGISGHLTNSMAKTVQAGCKPYMPPERI-DGE 225
Query: 581 ---IYDFRADIFSLGLMMIEIA 599
YD RAD++SLG+ +IEIA
Sbjct: 226 TKSAYDVRADVWSLGITIIEIA 247
>At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 561
Score = 77.8 bits (190), Expect = 5e-14
Identities = 42/142 (29%), Positives = 84/142 (58%), Gaps = 4/142 (2%)
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
+++F+ ++ + ++T++ G+L +F+ + + + L ++ + ++I + +I
Sbjct: 306 VIKFVGAYKDPPVYCVLTQYLPEGSLRSFLHK---PENRSLPLKKLIEFAIDIARGMEYI 362
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDGI 581
H S I+H DLKP NVLI E +LK+ADFG+A + D ++ G ++APE+I+
Sbjct: 363 H-SRRIIHRDLKPENVLIDEEFHLKIADFGIACEEEYCDMLADDPGTYRWMAPEMIKRKP 421
Query: 582 YDFRADIFSLGLMMIEIAANVI 603
+ +AD++S GL++ E+ A I
Sbjct: 422 HGRKADVYSFGLVLWEMVAGAI 443
>At5g38260 [T] KOG1187 Serine/threonine protein kinase
Length = 638
Score = 77.8 bits (190), Expect = 5e-14
Identities = 65/216 (30%), Positives = 111/216 (51%), Gaps = 27/216 (12%)
Query: 392 LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDS 451
+T FS+ +GKG F TVY + G K A+K ++ K N + I + +M T +
Sbjct: 319 ITKLFSHT--LGKGGFGTVYGGNLCD-GRKVAVKILKDFKSNGEDFINEVASMSQTSHVN 375
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
+ + ++ F S + Y EF ENG+LD F+ E K L+ +++I
Sbjct: 376 IVS-------LLGFCYEGSKRAIVY---EFLENGSLDQFLSEK---KSLNLDVSTLYRIA 422
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKS----FEN 565
+ + L ++H C IVH D+KP N+L+ K++DFG+A KL + +S +
Sbjct: 423 LGVARGLDYLHHGCKTRIVHFDIKPQNILLDDTFCPKVSDFGLA-KLCEKRESILSLLDA 481
Query: 566 EGDREYIAPEIIRDGIY---DFRADIFSLGLMMIEI 598
G YIAPE+ G+Y ++D++S G++++E+
Sbjct: 482 RGTIGYIAPEVF-SGMYGRVSHKSDVYSYGMLVLEM 516
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 77.8 bits (190), Expect = 5e-14
Identities = 54/202 (26%), Positives = 100/202 (48%), Gaps = 20/202 (9%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSV--RPTKHNFTNRILQEINMLSTIQDSVTNDTEGK 459
+G G F+ V+ +GL+ A+K + + + +L+EI++LSTI
Sbjct: 16 IGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHP-------- 67
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALR 519
I+ F + +++ E+C G+L +I H + + + + ++ L L+
Sbjct: 68 -NIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHF-----MRQLALGLQ 121
Query: 520 FIHDSCSIVHLDLKPANVLITFEGN---LKLADFGMATKLPIEDKSFENEGDREYIAPEI 576
+ + +H DLKP N+L++ + LK+ DFG A L E + G Y+APEI
Sbjct: 122 VLQEK-HFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPESMAETFCGSPLYMAPEI 180
Query: 577 IRDGIYDFRADIFSLGLMMIEI 598
IR+ YD +AD++S G ++ ++
Sbjct: 181 IRNQKYDAKADLWSAGAILFQL 202
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 77.8 bits (190), Expect = 5e-14
Identities = 56/215 (26%), Positives = 107/215 (49%), Gaps = 29/215 (13%)
Query: 389 DFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR----ILQEINM 444
D+H+ + ++G+G F VY+ TG A+K + K T++ + QEI +
Sbjct: 5 DYHV------IELVGEGSFGRVYKGRRKYTGQTVAMKFIM--KQGKTDKDIHSLRQEIEI 56
Query: 445 LSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED 504
L ++ E I+E + S+ + F ++TEF + + + + ++Q
Sbjct: 57 LRKLKH---------ENIIEMLDSFENAREFCVVTEFAQGELFEILEDDKCLPEEQ---- 103
Query: 505 WRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFE 564
+ I ++ AL ++H + I+H D+KP N+LI +KL DFG A +
Sbjct: 104 --VQAIAKQLVKALDYLHSN-RIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLR 160
Query: 565 N-EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+ +G Y+APE++++ YD D++SLG+++ E+
Sbjct: 161 SIKGTPLYMAPELVKEQPYDRTVDLWSLGVILYEL 195
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 77.8 bits (190), Expect = 5e-14
Identities = 60/212 (28%), Positives = 106/212 (49%), Gaps = 19/212 (8%)
Query: 394 TKFSNVSIMGKGQFSTVYQVTFPETG----LKYAIKS--VRPTKHNFTNRILQEINMLST 447
+K V ++G+G F V+ E K +K VR K I +E+ ++S
Sbjct: 6 SKLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTEL-GLIKEEVYIISQ 64
Query: 448 IQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI 507
++ +IVEF+ S+SH G+ I+ E+ NG L IQ+ + + + R+
Sbjct: 65 LRHP---------HIVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQ-LPSGTGGVNQERL 114
Query: 508 WKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEG 567
++ + L ++H C ++H D+KP N+L+ +K+ADFG+A + G
Sbjct: 115 MGYFRDMVVGLEYLHIRC-VIHRDIKPENMLLDANDRVKIADFGIANVHAPSTQLQAGMG 173
Query: 568 DREYIAPEII-RDGIYDFRADIFSLGLMMIEI 598
Y+APE + G DF++D++SLGL++ E+
Sbjct: 174 TPMYMAPEAMSSQGKVDFKSDVWSLGLVLYEL 205
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 77.4 bits (189), Expect = 7e-14
Identities = 68/317 (21%), Positives = 136/317 (42%), Gaps = 39/317 (12%)
Query: 368 PTHLQPPEKQRSINASIMKNPDFHLTT---------------KFSNVSIMGKGQFSTVYQ 412
P QPP+ Q + + + H + ++ ++GKG F+ Y+
Sbjct: 39 PEESQPPQSQAQVPPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYE 98
Query: 413 VTFPETGLKYAIKSV---RPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSW 469
+T YA K + R K + +I +EI + + +++V+F +
Sbjct: 99 MTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHH---------KHVVQFYHYF 149
Query: 470 SHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVH 529
K + YI+ E+C ++ H++ ++ L + + + +I L+++H+ I+H
Sbjct: 150 EDKENIYILLEYCSRRSM-----AHILKARKVLTEPEVRYYLRQIVSGLKYLHEQ-EILH 203
Query: 530 LDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYIAPEIIRDGIYDFRADI 588
DLK N I LK+ DFG+A +L P+E + G Y++PE++ + +DI
Sbjct: 204 RDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDI 263
Query: 589 FSLGLMMIEIAAN---VILPDNGSAWHKLRSGDLSDAGRLSSAEIH--SSSLFSNKKDHT 643
++LG +M + + + +R + L + H +S L N +D
Sbjct: 264 WALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRP 323
Query: 644 NITDITTHETKIPAWVP 660
++ DI H+ + + P
Sbjct: 324 SLDDIIRHDFFLQGFTP 340
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 77.4 bits (189), Expect = 7e-14
Identities = 58/212 (27%), Positives = 105/212 (49%), Gaps = 25/212 (11%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQEINMLSTIQDSV 452
FS + +G+G F V V +T +A+K + R + +++E+ +LS +
Sbjct: 28 FSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRCIEKGVAANVIRELTLLSKMSHP- 86
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+IV ++ Y++++ G+L + +++Q + + R +
Sbjct: 87 --------FIVNLWYTFQDGDYMYMVSDLLLGGDL-----RYHLSQQGKFAEDRAKLYLC 133
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYI 572
EICLA+ ++H+ IVH D+KP N+L+ +G+ L D +AT+L + + G R Y+
Sbjct: 134 EICLAVEYLHEM-KIVHRDIKPENILLDEQGHAHLTDLNLATQLEDDQLATSYSGTRPYM 192
Query: 573 APEI------IRDGIYDFRADIFSLGLMMIEI 598
APEI I DG YD R D ++LG+ E+
Sbjct: 193 APEIYATYLEIEDG-YDSRVDWWALGVCFYEM 223
>YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 842
Score = 77.0 bits (188), Expect = 9e-14
Identities = 68/254 (26%), Positives = 114/254 (44%), Gaps = 36/254 (14%)
Query: 360 IMTKLRNDPTHLQPPEKQRSI-------NASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQ 412
IM+KL+ + P + + I + S+ H+ T+ + + ++
Sbjct: 529 IMSKLKKVTVNADPSQCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINN-------D 581
Query: 413 VTFPETGLKYAIK----SVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISS 468
+ P G K AIK S +P K N IL V D+ K IV F+ +
Sbjct: 582 IDEPHVGDKVAIKQMVLSKQPRKELIVNEIL------------VMKDSRHKN-IVNFLEA 628
Query: 469 WSHKGS-FYIMTEFCENGNLDAFIQEHVIAKQQR--LEDWRIWKIIVEICLALRFIHDSC 525
+ +++ EF E G+L I+ L + +I I+ E C L+F+HD
Sbjct: 629 YLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDK- 687
Query: 526 SIVHLDLKPANVLITFEGNLKLADFGMATKLPIE-DKSFENEGDREYIAPEIIRDGIYDF 584
I+H D+K NVL+ +K+ DFG +L + K G ++APE+++ YD
Sbjct: 688 HIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDE 747
Query: 585 RADIFSLGLMMIEI 598
+ D++SLG+M IE+
Sbjct: 748 KIDVWSLGIMTIEM 761
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 77.0 bits (188), Expect = 9e-14
Identities = 55/213 (25%), Positives = 99/213 (45%), Gaps = 22/213 (10%)
Query: 386 KNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINML 445
K+ +HL ++G+G + VY+ T AIK V N I+ EI++L
Sbjct: 21 KSVQYHLK------QVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLL 74
Query: 446 STIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDW 505
+ + IV++ YI+ E+C NG+L I L +
Sbjct: 75 KNLNHN---------NIVKYHGFIRKSYELYILLEYCANGSLRRLISR----SSTGLSEN 121
Query: 506 RIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN 565
+ + L L+++H ++H D+K AN+L++ + +KLADFG++T + +
Sbjct: 122 ESKTYVTQTLLGLKYLHGE-GVIHRDIKAANILLSADNTVKLADFGVST--IVNSSALTL 178
Query: 566 EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G ++APEI+ + +DI+SLG ++E+
Sbjct: 179 AGTLNWMAPEILGNRGASTLSDIWSLGATVVEM 211
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 77.0 bits (188), Expect = 9e-14
Identities = 52/204 (25%), Positives = 99/204 (48%), Gaps = 13/204 (6%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++GKG F V QV +T YA+K+++ I+ + T+ +
Sbjct: 230 FELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKA------HIVSRSEVDHTLAERTVLA 283
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+IV S+ G Y++ F G L H + ++ + +R I E+
Sbjct: 284 QVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELF-----HHLQREGCFDTYRAKFYIAELL 338
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMA-TKLPIEDKSFENEGDREYIAP 574
+AL +H+ ++++ DLKP N+L+ + G++ L DFG+ + D++ G EY+AP
Sbjct: 339 VALECLHEF-NVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAP 397
Query: 575 EIIRDGIYDFRADIFSLGLMMIEI 598
E++ Y D ++LG+++ E+
Sbjct: 398 ELLLGHGYTKVVDWWTLGVLLYEM 421
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 77.0 bits (188), Expect = 9e-14
Identities = 60/208 (28%), Positives = 101/208 (47%), Gaps = 28/208 (13%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVRPTK--HNFTNRILQEINMLSTIQDSVTNDTEG 458
I+GKG F V + T ET K+AIK V K + + +E+N+L +++
Sbjct: 121 ILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK--------- 171
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
E+I+ + Y++ E CE+G L +E + K E+ W II + A+
Sbjct: 172 HEHIIHLEQVFETPKKMYLVMELCEDGEL----KEILDRKGHFSENETRW-IIQSLASAI 226
Query: 519 RFIHDSCSIVHLDLKPANVLI---------TFEGNLKLADFGMATKLPIEDKSFENE--G 567
++H++ IVH DLK N+++ N+K+ DFG+A K ++ G
Sbjct: 227 AYLHNN-DIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCG 285
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMM 595
Y+APE+I Y + DI+S+G++M
Sbjct: 286 TPIYMAPEVISAHDYSQQCDIWSIGVVM 313
>At3g13690 [T] KOG1187 Serine/threonine protein kinase
Length = 753
Score = 77.0 bits (188), Expect = 9e-14
Identities = 56/212 (26%), Positives = 98/212 (45%), Gaps = 20/212 (9%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T FS + + +G + +V++ PE G A+K + E+ +LS Q
Sbjct: 408 TGGFSQANFLAEGGYGSVHRGVLPE-GQVVAVKQHKLASSQGDVEFCSEVEVLSCAQH-- 464
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
+V I ++ E+ NG+LD+ H+ +Q+ +W KI
Sbjct: 465 -------RNVVMLIGFCIEDSRRLLVYEYICNGSLDS----HLYGRQKETLEWPARQKIA 513
Query: 512 VEICLALRFIHDSCS---IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-- 566
V LR++H+ C IVH D++P N+LIT + + DFG+A P + +
Sbjct: 514 VGAARGLRYLHEECRVGCIVHRDMRPNNILITHDNEPLVGDFGLARWQPDGEMGVDTRVI 573
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G Y+APE + G +AD++S G++++E+
Sbjct: 574 GTFGYLAPEYAQSGQITEKADVYSFGVVLVEL 605
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 77.0 bits (188), Expect = 9e-14
Identities = 52/209 (24%), Positives = 103/209 (48%), Gaps = 20/209 (9%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+GKG+F +V + G ++A K+++ + + +E+ ++ + G
Sbjct: 113 IGKGKFGSVRICKSRKNGTEFACKTLKKGEET----VHREVEIMQHLS--------GHPR 160
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
+V + + F+++ E C G L I + V K R + R I ++ L + +
Sbjct: 161 VVTLHAVYEESDCFHLVMELCSGGRL---IDQMV--KVGRYSEQRAANIFKDLMLVINYC 215
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDGI 581
H+ +VH D+KP N+L+T G ++LADFG+A ++ G Y+APE++ +
Sbjct: 216 HEM-GVVHRDIKPENILLTAAGKIQLADFGLAMRIAKGQTLSGLAGSPAYVAPEVLSEN- 273
Query: 582 YDFRADIFSLGLMMIEIAANVILPDNGSA 610
Y + D++S G+++ + + V LP G +
Sbjct: 274 YSEKVDVWSAGVLLYALLSGV-LPFKGDS 301
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 77.0 bits (188), Expect = 9e-14
Identities = 63/207 (30%), Positives = 103/207 (49%), Gaps = 20/207 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK-HNFTNRILQEINMLSTIQDSVTN 454
F+ +GKG F V++ T AIK + + + + I QEI +LS
Sbjct: 13 FTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDSP--- 69
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGN-LDAFIQEHVIAKQQRLEDWRIWKIIVE 513
Y+ ++ S+ +I+ E+ G+ LD + K E+ I I+ E
Sbjct: 70 ------YVTKYYGSFLKGTKLWIIMEYLGGGSALD-------LMKAGSFEEMHIGIILRE 116
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP-IEDKSFENEGDREYI 572
+ L ++H + H D+K ANVL++ +G++KLADFG+A +L K G ++
Sbjct: 117 VLKGLDYLHSERKL-HRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWM 175
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEIA 599
APE+I+ YD +ADI+SLG+ IE+A
Sbjct: 176 APEVIKQSQYDAKADIWSLGITAIELA 202
>Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 544
Score = 76.6 bits (187), Expect = 1e-13
Identities = 53/205 (25%), Positives = 100/205 (47%), Gaps = 17/205 (8%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTN 454
K++ +G+G TVY TG + AIK + + I+ EI ++ ++
Sbjct: 267 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNP--- 323
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
IV ++ S+ +++ E+ G+L + E +++ +I + E
Sbjct: 324 ------NIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC------MDEGQIAAVCREC 371
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENEGDREYIA 573
AL F+H + ++H D+K N+L+ +G++KL DFG ++ P + K G ++A
Sbjct: 372 LQALDFLHSN-QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMA 430
Query: 574 PEIIRDGIYDFRADIFSLGLMMIEI 598
PE++ Y + DI+SLG+M IE+
Sbjct: 431 PEVVTRKAYGPKVDIWSLGIMAIEM 455
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 76.6 bits (187), Expect = 1e-13
Identities = 61/207 (29%), Positives = 99/207 (47%), Gaps = 18/207 (8%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT---KHNFTNRILQEINMLSTIQDSV 452
F ++ +GKG F VYQV ET YA+K + K N ++ E N+L +
Sbjct: 94 FDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVL------I 147
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
N ++V S+ +K Y + + G L + +Q +++ + R
Sbjct: 148 NNFKH--PFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQ-----REKHFSESRSRFYAA 200
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-GDREY 571
EI AL ++H+ +I++ DLKP N+L+ +G L L DFG+ + K+ G EY
Sbjct: 201 EIACALGYLHEK-NIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEY 259
Query: 572 IAPEIIRDGIYDFRADIFSLGLMMIEI 598
+APEII YD D + LG ++ E+
Sbjct: 260 LAPEIILKKPYDKTVDWWCLGSVLYEM 286
>At5g56790 [T] KOG1187 Serine/threonine protein kinase
Length = 710
Score = 76.6 bits (187), Expect = 1e-13
Identities = 59/214 (27%), Positives = 98/214 (45%), Gaps = 18/214 (8%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T FS S + +G F +V+ T P+ G A+K + E+ +LS Q
Sbjct: 370 TKGFSKGSFLAEGGFGSVHLGTLPD-GQIIAVKQYKIASTQGDREFCSEVEVLSCAQH-- 426
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED--WRI-WK 509
+V I G ++ E+ NG+L + + + ++ E W K
Sbjct: 427 -------RNVVMLIGLCVEDGKRLLVYEYICNGSLHSHLYDIKVSIGMGREPLGWSARQK 479
Query: 510 IIVEICLALRFIHDSCS---IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
I V LR++H+ C IVH D++P N+L+T + + DFG+A P DK E
Sbjct: 480 IAVGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDFEPLVGDFGLARWQPEGDKGVETR 539
Query: 567 --GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G Y+APE + G +AD++S G++++E+
Sbjct: 540 VIGTFGYLAPEYAQSGQITEKADVYSFGVVLVEL 573
>At3g19300 [T] KOG1187 Serine/threonine protein kinase
Length = 663
Score = 76.6 bits (187), Expect = 1e-13
Identities = 70/304 (23%), Positives = 130/304 (42%), Gaps = 52/304 (17%)
Query: 400 SIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGK 459
+++G+G F TVY+ F GL A+K + + + +EI +L+ +
Sbjct: 330 AVIGRGGFGTVYKAEF-SNGLVAAVKKMNKSSEQAEDEFCREIELLARLHH--------- 379
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKIIVEICLAL 518
++V + K +++ E+ ENG+L ++H+ + ++ W KI +++ AL
Sbjct: 380 RHLVALKGFCNKKNERFLVYEYMENGSL----KDHLHSTEKSPLSWESRMKIAIDVANAL 435
Query: 519 RFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMA-----TKLPIEDKSFENEGDREY 571
++H C + H D+K +N+L+ KLADFG+A + E + + G Y
Sbjct: 436 EYLHFYCDPPLCHRDIKSSNILLDEHFVAKLADFGLAHASRDGSICFEPVNTDIRGTPGY 495
Query: 572 IAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSGDLSDAGRLSSAEIH 631
+ PE + ++D++S G++++EI D G +L
Sbjct: 496 VDPEYVVTHELTEKSDVYSYGVVLLEIITGKRAVDEGRNLVEL----------------- 538
Query: 632 SSSLFSNKKDHTNITDITTHETKIPAWVPKFLLDGISLE---RTIRWMIEPDYRDRPSAS 688
S L ++ ++ D K +DG LE +RW E + RPS
Sbjct: 539 SQPLLVSESRRIDLVDPRI----------KDCIDGEQLETVVAVVRWCTEKEGVARPSIK 588
Query: 689 DLLR 692
+LR
Sbjct: 589 QVLR 592
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 76.6 bits (187), Expect = 1e-13
Identities = 70/247 (28%), Positives = 115/247 (46%), Gaps = 32/247 (12%)
Query: 370 HLQPPEKQRSINASIMKNPDFHLTTK------FSNVSIMGKGQFSTVYQVTFPETGLKYA 423
H Q + S+N S+ D LT F + ++G G + VY+ +TG A
Sbjct: 3 HQQQQQLAPSVNCSL---DDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAA 59
Query: 424 IKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFI--SSWSHKGSFYIMTEF 481
IK + T+ I EIN+L +N Y FI S +++ E+
Sbjct: 60 IKVMDVTEDE-EEEIKLEINVLK----KYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEY 114
Query: 482 CENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITF 541
C G++ ++ K Q L++ I I EI L ++H + ++H D+K NVL+T
Sbjct: 115 CGAGSVTDLVKS---TKGQSLKEEWIAYICREILRGLSYLHSN-KVIHRDIKGQNVLLTD 170
Query: 542 EGNLKLADFGMATKLPIEDKSFENE----GDREYIAPEIIR-----DGIYDFRADIFSLG 592
+KL DFG++ +L D++ G ++APE+I D YD R+D++SLG
Sbjct: 171 NAEVKLVDFGVSAQL---DRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLG 227
Query: 593 LMMIEIA 599
+ +E+A
Sbjct: 228 ITALEMA 234
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 76.3 bits (186), Expect = 2e-13
Identities = 54/205 (26%), Positives = 99/205 (47%), Gaps = 14/205 (6%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + +G G F V+ + G YA+K + K R+ Q + T + +
Sbjct: 87 FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVL---KKEIVVRLKQ---VEHTNDERLMLS 140
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+I+ ++ +++ ++ E G L + ++ K QR + E+C
Sbjct: 141 IVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLR-----KSQRFPNPVAKFYAAEVC 195
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPE 575
LAL ++H S I++ DLKP N+L+ G++K+ DFG A +P D ++ G +YIAPE
Sbjct: 196 LALEYLH-SKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP--DVTYTLCGTPDYIAPE 252
Query: 576 IIRDGIYDFRADIFSLGLMMIEIAA 600
++ Y+ D +S G+++ E+ A
Sbjct: 253 VVSTKPYNKSIDWWSFGILIYEMLA 277
>CE25437 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 387
Score = 76.3 bits (186), Expect = 2e-13
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 16/198 (8%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+G G V + +TG+ A K V K + +I++E+ +L
Sbjct: 79 LGHGNGGVVNKCVHRKTGVIMARKLVHLEIKPSVRQQIVKELAVLHKCNSP--------- 129
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
+IV F ++ I E+ + +LD V+ K RL + + +I V + L +
Sbjct: 130 FIVGFYGAFVDNNDISICMEYMDGLSLDI-----VLKKVGRLPEKFVGRISVAVVRGLTY 184
Query: 521 IHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDG 580
+ D I+H D+KP+N+L+ G +KL DFG++ L I+ + G R Y+APE +
Sbjct: 185 LKDEIKILHRDVKPSNMLVNSNGEIKLCDFGVSGML-IDSMANSFVGTRSYMAPERLTGS 243
Query: 581 IYDFRADIFSLGLMMIEI 598
Y +DI+S GL ++E+
Sbjct: 244 HYTISSDIWSFGLSLVEL 261
>At5g54380 [T] KOG1187 Serine/threonine protein kinase
Length = 855
Score = 76.3 bits (186), Expect = 2e-13
Identities = 62/227 (27%), Positives = 103/227 (45%), Gaps = 31/227 (13%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T KF S++G G F VY+ T E G K A+K P EI MLS ++
Sbjct: 507 TNKFDESSLLGVGGFGRVYKGTL-EDGTKVAVKRGNPRSEQGMAEFRTEIEMLSKLRH-- 563
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
++V I + ++ E+ NG L + + + WK +
Sbjct: 564 -------RHLVSLIGYCDERSEMILVYEYMANGPLRSHLYGADLPPLS-------WKQRL 609
Query: 513 EICLA----LRFIHD--SCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN- 565
EIC+ L ++H S SI+H D+K N+L+ K+ADFG++ P D++ +
Sbjct: 610 EICIGAARGLHYLHTGASQSIIHRDVKTTNILLDENLVAKVADFGLSKTGPSLDQTHVST 669
Query: 566 --EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI-----AANVILP 605
+G Y+ PE R ++D++S G++++E+ A N +LP
Sbjct: 670 AVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLMEVLCCRPALNPVLP 716
>At5g35960 [T] KOG1187 Serine/threonine protein kinase
Length = 429
Score = 76.3 bits (186), Expect = 2e-13
Identities = 55/212 (25%), Positives = 108/212 (50%), Gaps = 21/212 (9%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T FS +++GKG ++ VY+ P + + +R L E+ +++ +
Sbjct: 131 TNNFSLENLIGKGGYAEVYKGMLPNGQMVAIKRLMRGNSEEIIVDFLSEMGIMAHVNHP- 189
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
N + Y VE G +++ E +G+L + + + +++++ W I +KI
Sbjct: 190 -NIAKLLGYGVE--------GGMHLVLELSPHGSLASMLY----SSKEKMK-WSIRYKIA 235
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLP---IEDKSFENE 566
+ + L ++H C I+H D+K AN+L+T + + ++ DFG+A LP + E
Sbjct: 236 LGVAEGLVYLHRGCHRRIIHRDIKAANILLTHDFSPQICDFGLAKWLPENWTHHIVSKFE 295
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G Y+APE + GI D + D+F+LG++++E+
Sbjct: 296 GTFGYLAPEYLTHGIVDEKTDVFALGVLLLEL 327
>7302458 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 596
Score = 76.3 bits (186), Expect = 2e-13
Identities = 66/239 (27%), Positives = 117/239 (48%), Gaps = 37/239 (15%)
Query: 363 KLRNDPTHLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKY 422
K ++ + LQPPEK F + +G+G + +VY+ E+
Sbjct: 27 KKLSEESLLQPPEKV------------------FDIMYKLGEGSYGSVYKAVHKESSSIV 68
Query: 423 AIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFC 482
AIK V P + + + I++EI+++ Y+V + S+ + +I E+C
Sbjct: 69 AIKLV-PVESDL-HEIIKEISIMQQCDSP---------YVVRYYGSYFKQYDLWICMEYC 117
Query: 483 ENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFE 542
G++ ++ +++ L + I I+ + L ++H I H D+K AN+L+ E
Sbjct: 118 GAGSVSDIMR----LRKKTLTEDEIATILSDTLQGLVYLHLRRKI-HRDIKAANILLNTE 172
Query: 543 GNLKLADFGMATKLPIEDKSFENE--GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
G KLADFG+A +L + + N G ++APE+I + YD ADI+SLG+ +E+A
Sbjct: 173 GYAKLADFGVAGQL-TDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMA 230
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 76.3 bits (186), Expect = 2e-13
Identities = 61/228 (26%), Positives = 113/228 (48%), Gaps = 22/228 (9%)
Query: 372 QPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT- 430
+P +K I ++ D + + + GKG F+ Y++ ET +A K V
Sbjct: 4 KPEDKSTDIPDRLV---DINQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKL 60
Query: 431 --KHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLD 488
KHN + QEI TI S+ + IV+F + + + YI+ E C+ ++
Sbjct: 61 MIKHNQKEKTAQEI----TIHRSLNHPN-----IVKFHNYFEDSQNIYIVLELCKKRSM- 110
Query: 489 AFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLA 548
++ H +++ + ++ I +I ++++HD+ I+H DLK N+ + ++K+
Sbjct: 111 --MELH--KRRKSITEFECRYYIYQIIQGVKYLHDN-RIIHRDLKLGNLFLNDLLHVKIG 165
Query: 549 DFGMATKLPIEDKSFENE-GDREYIAPEIIRDGIYDFRADIFSLGLMM 595
DFG+AT++ E + + G YIAPEI+ + F DI+S+G +M
Sbjct: 166 DFGLATRIEYEGERKKTLCGTPNYIAPEILTKKGHSFEVDIWSIGCVM 213
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 75.9 bits (185), Expect = 2e-13
Identities = 55/212 (25%), Positives = 103/212 (47%), Gaps = 15/212 (7%)
Query: 390 FHLTTKFSNVSI---MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLS 446
F ++ F N+ I +G G F V V + +A+K +R KH + + +
Sbjct: 444 FSSSSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRK-KHIVDTKQQEHVYSEK 502
Query: 447 TIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
I + + + +IV+ ++ Y++ E C G L + +++ + ++
Sbjct: 503 RILEELCSP-----FIVKLYRTFKDNKYVYMLLEACLGGELWSILRD-----RGSFDEPT 552
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
+ + A ++H I++ DLKP N+++ EG LKL DFG A K+ K++
Sbjct: 553 SKFCVACVTEAFDYLH-RLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFC 611
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G EY+APE+I + +DF D +SLG+++ E+
Sbjct: 612 GTPEYVAPEVILNKGHDFSVDFWSLGILVYEL 643
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 75.9 bits (185), Expect = 2e-13
Identities = 61/215 (28%), Positives = 102/215 (47%), Gaps = 18/215 (8%)
Query: 389 DFHLT-TKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQEINM 444
+ HLT +FS I+G+G F VY +TG YA+K + R L E M
Sbjct: 183 NIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIM 242
Query: 445 LSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED 504
LS + T +IV ++ + + G+L + +H + ++ +
Sbjct: 243 LSLVS------TGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRF 296
Query: 505 WRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFE 564
+ EI L L +H+ +V+ DLKPAN+L+ G+ +++D G+A + K
Sbjct: 297 YA-----TEIILGLEHVHNRF-VVYRDLKPANILLDEHGHARISDLGLACDFS-KKKPHA 349
Query: 565 NEGDREYIAPEIIRDG-IYDFRADIFSLGLMMIEI 598
+ G Y+APE+++ G YD AD FSLG M+ ++
Sbjct: 350 SVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKL 384
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 75.9 bits (185), Expect = 2e-13
Identities = 63/206 (30%), Positives = 99/206 (47%), Gaps = 20/206 (9%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTK--HNFTNRILQEINMLSTIQDSVTNDTEGK 459
+GKGQ V TG K AIK V K + ++ +EI +L I+
Sbjct: 57 LGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHP-------- 108
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALR 519
++++ + +K Y++ E G L ++ K+ RL K +I AL
Sbjct: 109 -HVLKLHDVYENKKYLYLVLEHVSGGELFDYL-----VKKGRLTPKEARKFFRQIVSALD 162
Query: 520 FIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-GDREYIAPEIIR 578
F H S SI H DLKP N+L+ + N+++ADFGMA+ L + D E G Y PE+I+
Sbjct: 163 FCH-SYSICHRDLKPENLLLDEKNNIRIADFGMAS-LQVGDSLLETSCGSPHYACPEVIK 220
Query: 579 DGIYD-FRADIFSLGLMMIEIAANVI 603
YD RAD++S G+++ + +
Sbjct: 221 GEKYDGRRADMWSCGVILFALLVGAL 246
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 75.9 bits (185), Expect = 2e-13
Identities = 61/213 (28%), Positives = 102/213 (47%), Gaps = 17/213 (7%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++G G + VY+ +T AIK + + + I EINML
Sbjct: 21 FELIEVVGNGTYGQVYKGRHVKTAQLAAIK-IMNINEDEEDEIKLEINMLKKHSHHRNVA 79
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
T +I + SS +++ EFC +G++ ++ K L++ I I EI
Sbjct: 80 TYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKN---TKGGSLKEEWIAYICREIL 136
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDREY 571
L +H S ++H D+K NVL+T +KL DFG++ +L DK+ G +
Sbjct: 137 RGLYHLHQS-KVIHRDIKGQNVLLTDSAEVKLVDFGVSAQL---DKTVGRRNTFIGTPYW 192
Query: 572 IAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
+APE+I + YD R+D++SLG+ +E+A
Sbjct: 193 MAPEVIACDESPEATYDSRSDLWSLGITALEMA 225
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 75.9 bits (185), Expect = 2e-13
Identities = 58/213 (27%), Positives = 101/213 (47%), Gaps = 21/213 (9%)
Query: 387 NPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLS 446
NPD K+ V +G G +VY T + AIK + I+ EI ++
Sbjct: 290 NPD----RKYRKVDKIGSGASGSVYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMR 345
Query: 447 TIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
+ + IV ++ S+ +++ E+ G+L + E ++ED
Sbjct: 346 ENKHA---------NIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTEC------QMEDGI 390
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFEN 565
I + E+ AL F+H S ++H D+K N+L+ +G++KL DFG +L P + K
Sbjct: 391 IAAVCREVLQALEFLH-SRHVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQRKRTTM 449
Query: 566 EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G ++APE++ Y + D++SLG+M IE+
Sbjct: 450 VGTPYWMAPEVVTRKQYGPKVDVWSLGIMAIEM 482
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 75.9 bits (185), Expect = 2e-13
Identities = 61/213 (28%), Positives = 102/213 (47%), Gaps = 17/213 (7%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++G G + VY+ +T AIK + + + I EINML
Sbjct: 21 FELIEVVGNGTYGQVYKGRHVKTAQLAAIK-IMNINEDEEDEIKLEINMLKKHSHHRNVA 79
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
T +I + SS +++ EFC +G++ ++ K L++ I I EI
Sbjct: 80 TYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKN---TKGGSLKEEWIAYICREIL 136
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDREY 571
L +H S ++H D+K NVL+T +KL DFG++ +L DK+ G +
Sbjct: 137 RGLYHLHQS-KVIHRDIKGQNVLLTDSAEVKLVDFGVSAQL---DKTVGRRNTFIGTPYW 192
Query: 572 IAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
+APE+I + YD R+D++SLG+ +E+A
Sbjct: 193 MAPEVIACDESPEATYDSRSDLWSLGITALEMA 225
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 75.9 bits (185), Expect = 2e-13
Identities = 61/213 (28%), Positives = 102/213 (47%), Gaps = 17/213 (7%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++G G + VY+ +T AIK + + + I EINML
Sbjct: 21 FELIEVVGNGTYGQVYKGRHVKTAQLAAIK-IMNINEDEEDEIKLEINMLKKHSHHRNVA 79
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
T +I + SS +++ EFC +G++ ++ K L++ I I EI
Sbjct: 80 TYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKN---TKGGSLKEEWIAYICREIL 136
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDREY 571
L +H S ++H D+K NVL+T +KL DFG++ +L DK+ G +
Sbjct: 137 RGLYHLHQS-KVIHRDIKGQNVLLTDSAEVKLVDFGVSAQL---DKTVGRRNTFIGTPYW 192
Query: 572 IAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
+APE+I + YD R+D++SLG+ +E+A
Sbjct: 193 MAPEVIACDESPEATYDSRSDLWSLGITALEMA 225
>At1g24030 [T] KOG1187 Serine/threonine protein kinase
Length = 303
Score = 75.9 bits (185), Expect = 2e-13
Identities = 85/331 (25%), Positives = 146/331 (43%), Gaps = 57/331 (17%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVR-PT--KHNFTNRILQEINMLSTIQ 449
T+ FS+ +++GKG F VYQ T +TG AIK + PT K + E+++LS +
Sbjct: 5 TSSFSDENLLGKGGFGRVYQGTL-KTGEVVAIKKMDLPTFKKADGEREFRVEVDILSRL- 62
Query: 450 DSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWK 509
D ++ + + H+ +++ E+ +NGNL Q+H+ AK W
Sbjct: 63 -----DHPNLVSLIGYCADGKHR---FLVYEYMQNGNL----QDHLNAKIS-------WP 103
Query: 510 IIVEICLA----LRFIHDSCS----IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDK 561
I + I L L ++H S S IVH D K NVL+ N K++DFG+A +P E K
Sbjct: 104 IRLRIALGAAKGLAYLHSSSSVGIPIVHRDFKSTNVLLDSNYNAKISDFGLAKLMP-EGK 162
Query: 562 ----SFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSG 617
+ G Y PE G ++DI++ G++++E+ R+
Sbjct: 163 DTCVTARVLGTFGYFDPEYTSTGKLTLQSDIYAFGVVLLELLTG------------RRAV 210
Query: 618 DLSDAGRLSSAEIHSSSLFSNKKDHTNITDITTHETKIPAWVPKFLLDGISLERTIRWMI 677
DL+ + + ++ +++K + D+ D S R IR
Sbjct: 211 DLTQGPNEQNLVLQVRNILNDRKKLRKVIDVELPRNSYSMEAITMFADLAS--RCIR--- 265
Query: 678 EPDYRDRPSASDLLRTEELEYVELTRKTGAV 708
+ ++RPS D ++ EL+ + T G +
Sbjct: 266 -IESKERPSVMDCVK--ELQLIIYTNSKGGL 293
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 75.5 bits (184), Expect = 3e-13
Identities = 59/237 (24%), Positives = 109/237 (45%), Gaps = 22/237 (9%)
Query: 388 PDFHLTTKFSN----VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKH-NFTNRILQEI 442
PD H F I+G+G S V + T +YA+K + T +F+ ++E+
Sbjct: 8 PDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVREL 67
Query: 443 NMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRL 502
+ + + G I++ ++ F+++ + + G L ++ E V ++
Sbjct: 68 REATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEK-- 125
Query: 503 EDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKS 562
E +I + ++E+ L ++ IVH DLKP N+L+ N+KL DFG + +L ++
Sbjct: 126 ETRKIMRALLEVICTLHKLN----IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERL 181
Query: 563 FENEGDREYIAPEIIRDGI------YDFRADIFSLGLMMIEIAANVILPDNGSAWHK 613
E G Y+APEII + Y D++S G++M +L + WH+
Sbjct: 182 REVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMY-----TLLAGSPPFWHR 233
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 414
Score = 75.5 bits (184), Expect = 3e-13
Identities = 49/198 (24%), Positives = 101/198 (50%), Gaps = 17/198 (8%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR--ILQEINMLSTIQDSVTNDTEGK 459
+G+G+F+ V + ++G ++A K +R + R I+ EI +L QD+
Sbjct: 67 LGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDN-------- 118
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALR 519
+++ + ++ E+ G + + V +++ ++ + +++ +I +
Sbjct: 119 PWVINLHEVYETASEMILVLEYAAGGEI---FDQCVADREEAFKEKDVQRLMRQILEGVH 175
Query: 520 FIHDSCSIVHLDLKPANVLITFE---GNLKLADFGMATKLPIEDKSFENEGDREYIAPEI 576
F+H +VHLDLKP N+L+T E G++K+ DFG++ L ++ E G EY+APEI
Sbjct: 176 FLHTR-DVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEI 234
Query: 577 IRDGIYDFRADIFSLGLM 594
+ D++S+G++
Sbjct: 235 LSYDPISMATDMWSIGVL 252
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 75.5 bits (184), Expect = 3e-13
Identities = 62/242 (25%), Positives = 108/242 (44%), Gaps = 54/242 (22%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTK---HNFTNRILQEINMLSTIQDSV 452
F ++ ++G+G F V V +TG YA+K +R ++ T + E ++LS
Sbjct: 80 FESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADC-- 137
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+++V+ S+ + Y++ EF G++ ++ K+ L + I
Sbjct: 138 -------DWVVKMYYSFQDYSNLYLVMEFLPGGDMMT-----LLIKKDTLTEEATQFYIA 185
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKL---------------- 556
E LA++FIH S +H D+KP N+L+ G++KL+DFG+ T L
Sbjct: 186 EAALAIQFIH-SLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWPSTL 244
Query: 557 -------PIEDK-------------SFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMI 596
P E K ++ G +YIAPE+ + Y D +SLG++M
Sbjct: 245 PPDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMY 304
Query: 597 EI 598
E+
Sbjct: 305 EM 306
>At5g12000 [T] KOG1187 Serine/threonine protein kinase
Length = 703
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/242 (27%), Positives = 115/242 (47%), Gaps = 33/242 (13%)
Query: 375 EKQRSINASIMKNPDFH---------LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIK 425
EK R+++A + + + T +F+N +G+G + VY T T + AIK
Sbjct: 392 EKDRALSALVQNDVRYRKYSIDEIEVATERFANNRKIGEGGYGPVYHGTLDHTPV--AIK 449
Query: 426 SVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENG 485
+RP + QE+ +LS+I+ ++V + + G ++ EF +NG
Sbjct: 450 VLRPDAAQGKKQFQQEVEVLSSIRHP---------HMVLLLGACPEYGC--LVYEFMDNG 498
Query: 486 NLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCS--IVHLDLKPANVLITFEG 543
+L+ + L + ++I EI AL F+H + +VH DLKPAN+L+
Sbjct: 499 SLEDRLFRR--GNSPPLSWRKRFQIAAEIATALSFLHQAKPEPLVHRDLKPANILLDKNY 556
Query: 544 NLKLADFGMATKLPIEDKSFENE-------GDREYIAPEIIRDGIYDFRADIFSLGLMMI 596
K++D G+A +P + + G YI PE + G ++DIFSLG+M++
Sbjct: 557 VSKISDVGLARLVPASVANTVTQYHMTSAAGTFCYIDPEYQQTGKLTTKSDIFSLGIMLL 616
Query: 597 EI 598
+I
Sbjct: 617 QI 618
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 75.5 bits (184), Expect = 3e-13
Identities = 73/286 (25%), Positives = 124/286 (42%), Gaps = 23/286 (8%)
Query: 385 MKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKH---NFTNRILQE 441
M+N LT ++ ++G+G F+ VY T AIK + K + +I +E
Sbjct: 1 MENKPSVLTERYEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKRE 60
Query: 442 INMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQR 501
I+++ + +VE + K Y + E+C+ G L + +AK +
Sbjct: 61 ISVMRIAKHP---------NVVELYEVMATKSRIYFVIEYCKGGELF-----NKVAKGKL 106
Query: 502 LEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDK 561
ED WK ++ A+ F H S + H D+KP N+L+ NLK++DFG++ + +
Sbjct: 107 KEDVA-WKYFYQLISAVDFCH-SRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQ 164
Query: 562 S---FENEGDREYIAPEII-RDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKLRSG 617
G Y+APE+I R G +ADI+S G+++ + A + + + R
Sbjct: 165 DGLLHTTCGTPAYVAPEVINRKGYEGTKADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKI 224
Query: 618 DLSDAGRLSSAEIHSSSLFSNKKDHTNITDITTHETKIPAWVPKFL 663
+D S L D + T IT + K +W K L
Sbjct: 225 GKADFKCPSWFAPEVKRLLCKMLDPNHETRITIAKIKESSWFRKGL 270
>At3g28690 [T] KOG1187 Serine/threonine protein kinase
Length = 476
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/246 (26%), Positives = 109/246 (43%), Gaps = 30/246 (12%)
Query: 369 THLQPPEKQRSINASIMKNPDFHLTTK-FSNVSIMGKGQFSTVYQVTF---------PET 418
T L E + S I D L T+ F S++G+G F V++ P T
Sbjct: 98 TPLMSGELKYSSKLRIFMFNDLKLATRNFRPESLLGEGGFGCVFKGWIEENGTAPVKPGT 157
Query: 419 GLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIM 478
GL A+K++ P L EIN L + +V+ + + ++
Sbjct: 158 GLTVAVKTLNPDGLQGHKEWLAEINFLGNLVHPS---------LVKLVGYCMEEDQRLLV 208
Query: 479 TEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKIIVEICLALRFIHDSCS--IVHLDLKPA 535
EF G+L+ H+ + L W + KI + L F+H+ +++ D K +
Sbjct: 209 YEFMPRGSLE----NHLFRRTLPLP-WSVRMKIALGAAKGLAFLHEEAEKPVIYRDFKTS 263
Query: 536 NVLITFEGNLKLADFGMATKLPIEDKSFENE---GDREYIAPEIIRDGIYDFRADIFSLG 592
N+L+ E N KL+DFG+A P E KS + G Y APE + G ++D++S G
Sbjct: 264 NILLDGEYNAKLSDFGLAKDAPDEKKSHVSTRVMGTYGYAAPEYVMTGHLTTKSDVYSFG 323
Query: 593 LMMIEI 598
++++EI
Sbjct: 324 VVLLEI 329
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 75.1 bits (183), Expect = 4e-13
Identities = 64/205 (31%), Positives = 104/205 (50%), Gaps = 20/205 (9%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
++GKG + VY ++ AIK + ++ + +EI + ++ +
Sbjct: 685 VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKH---------K 735
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED--WRIWKIIVEICLAL 518
IV+++ S+S G I E G+L A ++ +K L+D I +I L
Sbjct: 736 NIVQYLGSFSENGFIKIFMEQVPGGSLSALLR----SKWGPLKDNEQTIGFYTKQILEGL 791
Query: 519 RFIHDSCSIVHLDLKPANVLI-TFEGNLKLADFGMATKLPIEDKSFEN-EGDREYIAPEI 576
+++HD+ IVH D+K NVLI T+ G LK++DFG + +L + E G +Y+APEI
Sbjct: 792 KYLHDN-QIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEI 850
Query: 577 IRDGI--YDFRADIFSLGLMMIEIA 599
I G Y ADI+SLG +IE+A
Sbjct: 851 IDKGPRGYGKAADIWSLGCTIIEMA 875
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 75.1 bits (183), Expect = 4e-13
Identities = 58/220 (26%), Positives = 108/220 (48%), Gaps = 20/220 (9%)
Query: 385 MKNPDF-HLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHN--FTNRILQE 441
MK P+ ++ KF + ++G+G + V + ET AIK + ++ N L+E
Sbjct: 1 MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE 60
Query: 442 INMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQR 501
+ ML T++ +E IVE ++ +G Y++ E+ E L+ + ++
Sbjct: 61 LKMLRTLK---------QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEK 111
Query: 502 LEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDK 561
++ + I ++ A+ + H + IVH D+KP N+LI+ LKL DFG A L +
Sbjct: 112 VKSY-----IYQLIKAIHWCHKN-DIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNN 165
Query: 562 SFENE--GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
+ E R Y +PE++ Y D++S+G ++ E++
Sbjct: 166 ANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELS 205
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 75.1 bits (183), Expect = 4e-13
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 18/215 (8%)
Query: 389 DFHLTTK-FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQEINM 444
+ HLT FS I+G+G F VY +TG YA+K + R L E M
Sbjct: 183 NIHLTMNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRIKMKQGETLALNERIM 242
Query: 445 LSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED 504
LS + T +IV ++ + + G+L + +H + + D
Sbjct: 243 LSLVS------TGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEA---D 293
Query: 505 WRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFE 564
R + EI L L +H+ +V+ DLKPAN+L+ G+++++D G+A + K
Sbjct: 294 MRFYA--AEIILGLEHMHNRF-VVYRDLKPANILLDEHGHVRISDLGLACDFS-KKKPHA 349
Query: 565 NEGDREYIAPEIIRDGI-YDFRADIFSLGLMMIEI 598
+ G Y+APE+++ G+ YD AD FSLG M+ ++
Sbjct: 350 SVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKL 384
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 75.1 bits (183), Expect = 4e-13
Identities = 51/211 (24%), Positives = 100/211 (47%), Gaps = 18/211 (8%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
+ G+G+F V++ TGLK A K ++ + EI++++ + +
Sbjct: 179 LFGRGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHA--------- 229
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
+++ ++ K ++ E+ + G L + +I + L + + +IC +R
Sbjct: 230 NLIQLYDAFESKNDIVLVMEYVDGGELF----DRIIDESYNLTELDTILFMKQICEGIRH 285
Query: 521 IHDSCSIVHLDLKPANVLITFEG--NLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
+H I+HLDLKP N+L +K+ DFG+A + +K N G E++APE++
Sbjct: 286 MHQMY-ILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 344
Query: 579 DGIYDFRADIFSLGLM--MIEIAANVILPDN 607
F D++S+G++ M+ + L DN
Sbjct: 345 YDFVSFPTDMWSVGVIAYMLLSGLSPFLGDN 375
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 75.1 bits (183), Expect = 4e-13
Identities = 61/205 (29%), Positives = 99/205 (47%), Gaps = 20/205 (9%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
++GKG + TVY +T ++ AIK V + +EI + S ++
Sbjct: 584 VLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLR---------HR 634
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV--EICLAL 518
IV ++ S S G F I E G+L ++ K L+D +I L
Sbjct: 635 NIVRYLGSCSENGFFKIFMEQVPGGSLSDLLE----TKWGPLKDNESTMAFYSKQILEGL 690
Query: 519 RFIHDSCSIVHLDLKPANVLI-TFEGNLKLADFGMATKLP-IEDKSFENEGDREYIAPEI 576
+++H+ IVH D+K NVL+ T+ G +K++DFG + +L I + G +Y+APE+
Sbjct: 691 KYLHEQ-DIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAPEV 749
Query: 577 IRDGI--YDFRADIFSLGLMMIEIA 599
I G+ Y ADI+S G +E+A
Sbjct: 750 IDQGVRGYGPAADIWSFGCTNVEMA 774
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 74.7 bits (182), Expect = 5e-13
Identities = 66/214 (30%), Positives = 102/214 (46%), Gaps = 21/214 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V ++G G + VY+ +TG AIK + T+ I EINML
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDE-EEEIKLEINMLKKYSHHRNIA 83
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRL-EDWRIWKIIVEI 514
T +I + S H +++ EFC G++ ++ K L EDW I I EI
Sbjct: 84 TYYGAFIKK--SPPGHDDQLWLVMEFCGAGSITDLVKN---TKGNTLKEDW-IAYISREI 137
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDRE 570
L +H ++H D+K NVL+T +KL DFG++ +L D++ G
Sbjct: 138 LRGLAHLHIH-HVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPY 193
Query: 571 YIAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
++APE+I D YD+R+D++S G+ IE+A
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMA 227
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 74.7 bits (182), Expect = 5e-13
Identities = 61/214 (28%), Positives = 105/214 (48%), Gaps = 26/214 (12%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPE-TGLKYAIKSVRPTKHNFTNRIL-QEINMLSTIQDSV 452
++S ++G G F+ V++ + T + AIKS+ + + +L +EI +L +Q
Sbjct: 8 EYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQH-- 65
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
E IV S +++ E+C G+L ++Q AK ED I +
Sbjct: 66 -------ENIVALYDVQELPNSVFLVMEYCNGGDLADYLQ----AKGTLSED-TIRVFLH 113
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGN---------LKLADFGMATKLPIEDKSF 563
+I A+R +H S I+H DLKP N+L+++ +K+ADFG A L +
Sbjct: 114 QIAAAMRILH-SKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAA 172
Query: 564 ENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIE 597
G Y+APE+I YD +AD++S+G ++ +
Sbjct: 173 TLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQ 206
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 74.7 bits (182), Expect = 5e-13
Identities = 54/197 (27%), Positives = 94/197 (47%), Gaps = 14/197 (7%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+G+G F+ V + TG K AIK + + + + + IQ + +
Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPN----- 122
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
I + + + S+Y++ E C GNL H I +++RLE+ + I ++ A+ +
Sbjct: 123 ITQLLDILETENSYYLVMELCPGGNL-----MHKIYEKKRLEESEARRYIRQLISAVEHL 177
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGM---ATKLPIEDKSFENEGDREYIAPEIIR 578
H + +VH DLK N+L+ + N+KL DFG+ A L D G Y APE++
Sbjct: 178 HRA-GVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA 236
Query: 579 DGIYDFRADIFSLGLMM 595
Y + D++S+G+ M
Sbjct: 237 RKKYGPKIDVWSIGVNM 253
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 74.7 bits (182), Expect = 5e-13
Identities = 67/266 (25%), Positives = 125/266 (46%), Gaps = 23/266 (8%)
Query: 335 SPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQR-SINASIMKNPDFHLT 393
+P P L P + + + P R H++P ++ S AS + P
Sbjct: 508 TPPPKPPRLYLPQEPTSEETP---------RTKRPHMEPRTRRGPSPPASPTRKPP--RL 556
Query: 394 TKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVT 453
F ++++G+G F V V F TG YAIK+++ + + I + + I ++V
Sbjct: 557 QDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEI-ESLYCEKRILEAV- 614
Query: 454 NDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVE 513
G +++ + + +TEF G+L I E V + Q R + +
Sbjct: 615 -GCTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHEDVFPEPQA----RFY--VAC 667
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDREYI 572
+ L L+F+H+ I++ DLK N+L+ +G LK+ADFG+ + + D++ G E++
Sbjct: 668 VVLGLQFLHEK-KIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFL 726
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEI 598
APE++ Y D ++LG+++ E+
Sbjct: 727 APEVLTQEAYTQAVDWWALGVLLYEM 752
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 74.7 bits (182), Expect = 5e-13
Identities = 65/239 (27%), Positives = 112/239 (46%), Gaps = 37/239 (15%)
Query: 375 EKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQV---TFPETGLKYAIK------ 425
EK S+ + P+ F + ++GKG + V+QV T TG +A+K
Sbjct: 70 EKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAM 129
Query: 426 ---SVRPTKHNFTNR-ILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEF 481
+ + T H R IL+E+ +IV+ I ++ G Y++ E+
Sbjct: 130 IVRNAKDTAHTKAERNILEEVK---------------HPFIVDLIYAFQTGGKLYLILEY 174
Query: 482 CENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITF 541
G L ++ I +ED + + EI +AL +H I++ DLKP N+++
Sbjct: 175 LSGGELFMQLEREGIF----MEDTACF-YLAEISMALGHLHQK-GIIYRDLKPENIMLNH 228
Query: 542 EGNLKLADFGMATKLPIEDKSFENE--GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+G++KL DFG+ K I D + + G EY+APEI+ ++ D +SLG +M ++
Sbjct: 229 QGHVKLTDFGLC-KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDM 286
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 74.7 bits (182), Expect = 5e-13
Identities = 68/237 (28%), Positives = 116/237 (48%), Gaps = 31/237 (13%)
Query: 394 TKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV--RPTKHNFTNRILQEINMLSTIQ-D 450
+K+ ++ +G+G F V++ +TG K A+K V K F L+EI +L ++ +
Sbjct: 17 SKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE 76
Query: 451 SVTNDTEGKEYIVEFISSWSH-----KGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDW 505
+V N ++E + + KGS Y++ +FCE+ A + +V+ K E
Sbjct: 77 NVVN-------LIEICRTKASPYNRCKGSIYLVFDFCEHDL--AGLLSNVLVKFTLSEIK 127
Query: 506 RIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN 565
R+ ++++ L +IH + I+H D+K ANVLIT +G LKLADFG+A + S N
Sbjct: 128 RVMQMLLN---GLYYIHRN-KILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPN 183
Query: 566 EGDRE-----YIAPEII---RDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKL 614
Y PE++ RD Y D++ G +M E+ + + H+L
Sbjct: 184 RYTNRVVTLWYRPPELLLGERD--YGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL 238
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 74.7 bits (182), Expect = 5e-13
Identities = 66/214 (30%), Positives = 102/214 (46%), Gaps = 21/214 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V ++G G + VY+ +TG AIK + T+ I EINML
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDE-EEEIKLEINMLKKYSHHRNIA 83
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRL-EDWRIWKIIVEI 514
T +I + S H +++ EFC G++ ++ K L EDW I I EI
Sbjct: 84 TYYGAFIKK--SPPGHDDQLWLVMEFCGAGSITDLVKN---TKGNTLKEDW-IAYISREI 137
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDRE 570
L +H ++H D+K NVL+T +KL DFG++ +L D++ G
Sbjct: 138 LRGLAHLHIH-HVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPY 193
Query: 571 YIAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
++APE+I D YD+R+D++S G+ IE+A
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMA 227
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 74.7 bits (182), Expect = 5e-13
Identities = 66/214 (30%), Positives = 102/214 (46%), Gaps = 21/214 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V ++G G + VY+ +TG AIK + T+ I EINML
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDE-EEEIKLEINMLKKYSHHRNIA 83
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRL-EDWRIWKIIVEI 514
T +I + S H +++ EFC G++ ++ K L EDW I I EI
Sbjct: 84 TYYGAFIKK--SPPGHDDQLWLVMEFCGAGSITDLVKN---TKGNTLKEDW-IAYISREI 137
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDRE 570
L +H ++H D+K NVL+T +KL DFG++ +L D++ G
Sbjct: 138 LRGLAHLHIH-HVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPY 193
Query: 571 YIAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
++APE+I D YD+R+D++S G+ IE+A
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMA 227
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 74.7 bits (182), Expect = 5e-13
Identities = 66/214 (30%), Positives = 102/214 (46%), Gaps = 21/214 (9%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F V ++G G + VY+ +TG AIK + T+ I EINML
Sbjct: 25 FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDE-EEEIKLEINMLKKYSHHRNIA 83
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRL-EDWRIWKIIVEI 514
T +I + S H +++ EFC G++ ++ K L EDW I I EI
Sbjct: 84 TYYGAFIKK--SPPGHDDQLWLVMEFCGAGSITDLVKN---TKGNTLKEDW-IAYISREI 137
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE----GDRE 570
L +H ++H D+K NVL+T +KL DFG++ +L D++ G
Sbjct: 138 LRGLAHLHIH-HVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPY 193
Query: 571 YIAPEIIR-----DGIYDFRADIFSLGLMMIEIA 599
++APE+I D YD+R+D++S G+ IE+A
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMA 227
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 74.7 bits (182), Expect = 5e-13
Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 16/264 (6%)
Query: 336 PSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQRSINASIMKNPDFHLTTK 395
P+P+ + L P PD M QP +IN NP+ T
Sbjct: 39 PTPTLSCLLLPVPPEL---PDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNAQ-PTD 94
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++GKG + V G YA+K ++ K + + Q M + SV
Sbjct: 95 FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQ--KKSILKKKEQSHIMA---ERSVLLK 149
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++V S+ Y + ++ G L +Q +++R + R E+
Sbjct: 150 NVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQ-----RERRFLEPRARFYAAEVA 204
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK-LPIEDKSFENEGDREYIAP 574
A+ ++H S +I++ DLKP N+L+ +G++ L DFG+ + + ED + G EY+AP
Sbjct: 205 SAIGYLH-SLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAP 263
Query: 575 EIIRDGIYDFRADIFSLGLMMIEI 598
E++R YD D + LG ++ E+
Sbjct: 264 EVLRKEPYDRAVDWWCLGAVLYEM 287
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 74.7 bits (182), Expect = 5e-13
Identities = 55/203 (27%), Positives = 89/203 (43%), Gaps = 11/203 (5%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F+ + +G G F V V K + +H R + I I +D
Sbjct: 375 FNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSD 434
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+IV ++ Y++ E C G L +++ + ED +
Sbjct: 435 -----FIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-----RGSFEDSTTRFYTACVV 484
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPE 575
A ++H S I++ DLKP N+++ G KL DFG A K+ K++ G EY+APE
Sbjct: 485 EAFAYLH-SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPE 543
Query: 576 IIRDGIYDFRADIFSLGLMMIEI 598
II + +D AD +SLG++M E+
Sbjct: 544 IILNKGHDISADYWSLGILMYEL 566
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 74.7 bits (182), Expect = 5e-13
Identities = 57/206 (27%), Positives = 104/206 (49%), Gaps = 15/206 (7%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLST-IQDSVTN 454
F+ + ++GKG F V V YA+K ++ + IL++ + T I+ V
Sbjct: 238 FNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKK------DVILEDDDTECTYIERRVLI 291
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
++ + S+ + + E+ G+L H I + ++ ++ R EI
Sbjct: 292 LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDL-----MHHIQQIKKFDEARTRFYACEI 346
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYI 572
+AL+F+H + +I++ DLK NVL+ +G++KLADFGMA + + G +YI
Sbjct: 347 VVALQFLHTN-NIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYI 405
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEI 598
+PEII+ +Y+ D +S G++M E+
Sbjct: 406 SPEIIKGQLYNEAVDFWSFGVLMYEM 431
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 74.7 bits (182), Expect = 5e-13
Identities = 57/206 (27%), Positives = 104/206 (49%), Gaps = 15/206 (7%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLST-IQDSVTN 454
F+ + ++GKG F V V YA+K ++ + IL++ + T I+ V
Sbjct: 375 FNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKK------DVILEDDDTECTYIERRVLI 428
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
++ + S+ + + E+ G+L H I + ++ ++ R EI
Sbjct: 429 LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDL-----MHHIQQIKKFDEARTRFYACEI 483
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYI 572
+AL+F+H + +I++ DLK NVL+ +G++KLADFGMA + + G +YI
Sbjct: 484 VVALQFLHTN-NIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYI 542
Query: 573 APEIIRDGIYDFRADIFSLGLMMIEI 598
+PEII+ +Y+ D +S G++M E+
Sbjct: 543 SPEIIKGQLYNEAVDFWSFGVLMYEM 568
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 74.7 bits (182), Expect = 5e-13
Identities = 57/214 (26%), Positives = 100/214 (46%), Gaps = 32/214 (14%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIK--------SVRPTKHNFTN-RILQEINMLS 446
F + +G G F V V ++G YA+K ++ +H RILQ I+
Sbjct: 52 FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDF-- 109
Query: 447 TIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
++V S+ + Y++ EF G + + ++ + R +
Sbjct: 110 -------------PFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLR-----RIGRFSEPH 151
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
+I LA ++H S +++ DLKP N+LI G LK+ DFG A + ++ +++
Sbjct: 152 SRFYAAQIVLAFEYLH-SLDLIYRDLKPENLLIDSTGYLKITDFGFAKR--VKGRTWTLC 208
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAA 600
G EY+APEII Y+ D ++LG+++ E+AA
Sbjct: 209 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 242
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 74.7 bits (182), Expect = 5e-13
Identities = 57/214 (26%), Positives = 100/214 (46%), Gaps = 32/214 (14%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIK--------SVRPTKHNFTN-RILQEINMLS 446
F + +G G F V V ++G YA+K ++ +H RILQ I+
Sbjct: 52 FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDF-- 109
Query: 447 TIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWR 506
++V S+ + Y++ EF G + + ++ + R +
Sbjct: 110 -------------PFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLR-----RIGRFSEPH 151
Query: 507 IWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE 566
+I LA ++H S +++ DLKP N+LI G LK+ DFG A + ++ +++
Sbjct: 152 SRFYAAQIVLAFEYLH-SLDLIYRDLKPENLLIDSTGYLKITDFGFAKR--VKGRTWTLC 208
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAA 600
G EY+APEII Y+ D ++LG+++ E+AA
Sbjct: 209 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 242
>At5g60080 [T] KOG1187 Serine/threonine protein kinase
Length = 377
Score = 74.7 bits (182), Expect = 5e-13
Identities = 54/216 (25%), Positives = 97/216 (44%), Gaps = 21/216 (9%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T F+ ++G+G + VY+ FPE G K + +N I ++ T+ ++
Sbjct: 70 TDNFAITHLIGQGTYGKVYRCKFPE-GHKVGAAKIH------SNGITDGLS--ETVAETT 120
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQ-----QRLEDWRI 507
T +++ + + ++ EF NG+LD + H Q R+ DW
Sbjct: 121 TLYAADHPNVIKLVGKYYGMEKSVLVYEFMPNGSLDHHLFAHARQVQGLTLPTRVLDWNT 180
Query: 508 -WKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIED------ 560
+I V + L ++H +H D+K N+L+ + KL DFG ATK+
Sbjct: 181 RLRIAVGVAEGLVYVHQGLYAIHRDIKVENILLDKDFVPKLTDFGFATKIVYNSDGVERL 240
Query: 561 KSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMI 596
+ F G + YIAPE + ++DI+S G++++
Sbjct: 241 REFNTRGTQGYIAPEADEFALVSTKSDIYSYGVLLL 276
>At5g39030 [T] KOG1187 Serine/threonine protein kinase
Length = 806
Score = 74.7 bits (182), Expect = 5e-13
Identities = 66/217 (30%), Positives = 110/217 (50%), Gaps = 29/217 (13%)
Query: 392 LTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDS 451
+T FS I+GKG F TVY G K A+K ++ K + + I + +M T +
Sbjct: 496 ITKSFSY--IIGKGGFGTVYGGNL-SNGRKVAVKVLKDLKGSAEDFINEVASMSQTSHVN 552
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
+ + ++ F S + Y EF ENG+LD F+ + K + ++ I
Sbjct: 553 IVS-------LLGFCFEGSKRAIVY---EFLENGSLDQFMSRN---KSLTQDVTTLYGIA 599
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNL--KLADFGMATKLPIEDKS----F 563
+ I L ++H C IVH D+KP N+L+ +GNL K++DFG+A KL + +S
Sbjct: 600 LGIARGLEYLHYGCKTRIVHFDIKPQNILL--DGNLCPKVSDFGLA-KLCEKRESVLSLM 656
Query: 564 ENEGDREYIAPEIIRD--GIYDFRADIFSLGLMMIEI 598
+ G YIAPE+ G ++D++S G+++I++
Sbjct: 657 DTRGTIGYIAPEVFSRMYGRVSHKSDVYSFGMLVIDM 693
>At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 74.7 bits (182), Expect = 5e-13
Identities = 54/203 (26%), Positives = 97/203 (47%), Gaps = 16/203 (7%)
Query: 399 VSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEG 458
V ++GKG V V TG +A+K ++ + E + Q+ N +
Sbjct: 73 VKVIGKGSSGVVQLVQHKWTGQFFALKVIQLN--------IDEAIRKAIAQELKINQSSQ 124
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
+V S+ G+ ++ E+ + G+L F++ + + D + I ++ L
Sbjct: 125 CPNLVTSYQSFYDNGAISLILEYMDGGSLADFLKS-----VKAIPDSYLSAIFRQVLQGL 179
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--GDREYIAPEI 576
++H I+H DLKP+N+LI G +K+ DFG++T + N G Y++PE
Sbjct: 180 IYLHHDRHIIHRDLKPSNLLINHRGEVKITDFGVSTVM-TNTAGLANTFVGTYNYMSPER 238
Query: 577 IRDGIYDFRADIFSLGLMMIEIA 599
I Y ++DI+SLGL+++E A
Sbjct: 239 IVGNKYGNKSDIWSLGLVVLECA 261
>At3g24550 [T] KOG1187 Serine/threonine protein kinase
Length = 652
Score = 74.7 bits (182), Expect = 5e-13
Identities = 61/245 (24%), Positives = 113/245 (45%), Gaps = 29/245 (11%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T FS +++G+G F V++ P +G + A+K ++ E+ ++S +
Sbjct: 277 TNGFSEANLLGQGGFGYVHKGILP-SGKEVAVKQLKAGSGQGEREFQAEVEIISRVHH-- 333
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
++V I ++ EF N NL+ H+ K + +W KI
Sbjct: 334 -------RHLVSLIGYCMAGVQRLLVYEFVPNNNLEF----HLHGKGRPTMEWSTRLKIA 382
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--- 566
+ L ++H+ C+ I+H D+K +N+LI F+ K+ADFG+A K+ + + +
Sbjct: 383 LGSAKGLSYLHEDCNPKIIHRDIKASNILIDFKFEAKVADFGLA-KIASDTNTHVSTRVM 441
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI--------AANVILPDNGSAWHKLRSGD 618
G Y+APE G ++D+FS G++++E+ A NV + D+ W +
Sbjct: 442 GTFGYLAPEYAASGKLTEKSDVFSFGVVLLELITGRRPVDANNVYVDDSLVDWARPLLNR 501
Query: 619 LSDAG 623
S+ G
Sbjct: 502 ASEEG 506
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 74.3 bits (181), Expect = 6e-13
Identities = 55/204 (26%), Positives = 97/204 (46%), Gaps = 13/204 (6%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++GKG F V QV +T YA+K++R + I+ + + T+ +
Sbjct: 347 FDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSY------IVSKSEVTHTLAERTVLA 400
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+IV S+ Y + F G L +Q K+ R + R E+
Sbjct: 401 RVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQ-----KEGRFDLSRARFYTAELL 455
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMA-TKLPIEDKSFENEGDREYIAP 574
AL +H +V+ DLKP N+L+ ++G++ L DFG+ + +DK+ G EY+AP
Sbjct: 456 CALDNLH-KLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAP 514
Query: 575 EIIRDGIYDFRADIFSLGLMMIEI 598
E++ Y D ++LG+++ E+
Sbjct: 515 ELLLGLGYTKAVDWWTLGVLLYEM 538
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 74.3 bits (181), Expect = 6e-13
Identities = 65/233 (27%), Positives = 114/233 (48%), Gaps = 22/233 (9%)
Query: 370 HLQPPE--KQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV 427
HL PE K+R +K DF L ++GKG F V+ F +T +AIK++
Sbjct: 358 HLPEPELNKERPSLQIKLKIEDFILH------KMLGKGSFGKVFLAEFKKTNQFFAIKAL 411
Query: 428 RPTKHNFTNRILQEINMLST-IQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGN 486
+ + +L + ++ T ++ V + ++ ++ K + + + E+ G+
Sbjct: 412 KK------DVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGD 465
Query: 487 LDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLK 546
L IQ + + R EI L L+F+H S IV+ DLK N+L+ +G++K
Sbjct: 466 LMYHIQSC-----HKFDLSRATFYAAEIILGLQFLH-SKGIVYRDLKLDNILLDKDGHIK 519
Query: 547 LADFGMATKLPIED-KSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+ADFGM + + D K+ G +YIAPEI+ Y+ D +S G+++ E+
Sbjct: 520 IADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEM 572
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 74.3 bits (181), Expect = 6e-13
Identities = 55/215 (25%), Positives = 102/215 (46%), Gaps = 32/215 (14%)
Query: 395 KFSNVSIMGKGQFSTVYQVTFPETGLKYAIK--------SVRPTKHNFTN-RILQEINML 445
+F + +G G F V V ETG YA+K ++ +H RILQ +N
Sbjct: 43 QFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF- 101
Query: 446 STIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDW 505
++V+ S+ + Y++ E+ G + + ++ + R +
Sbjct: 102 --------------PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLR-----RIGRFSEP 142
Query: 506 RIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFEN 565
+I L ++H S +++ DLKP N+LI +G +++ DFG A + ++ +++
Sbjct: 143 HARFYAAQIVLTFEYLH-SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGRTWTL 199
Query: 566 EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAA 600
G EY+APEII Y+ D ++LG+++ E+AA
Sbjct: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 234
>CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 850
Score = 74.3 bits (181), Expect = 6e-13
Identities = 62/208 (29%), Positives = 111/208 (52%), Gaps = 25/208 (12%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNF---TNRILQEINMLSTIQDSVTNDTEG 458
+G G F VY+ T+ G A+K R T+ + +E+++LS +
Sbjct: 522 IGSGSFGKVYKGTY--RGKLVAVKRYRAMAFGCKSETDMLCREVSILSRL---------A 570
Query: 459 KEYIVEFI-SSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLED--WRIWKIIVEIC 515
+V F+ +S F I+TEF ENG+L F +E+ K R+ D +R+ +I +++
Sbjct: 571 HPNVVAFVGTSLDDPSQFAIITEFVENGSL--FRRENGERKNYRVMDPAFRL-RISLDVA 627
Query: 516 LALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKL-PIEDKSFENE-GDREY 571
+R++H+S + ++H DL N+LI +G +ADFG + + ED++ + G+ +
Sbjct: 628 RGMRYLHESAAKPVIHRDLNSHNILIHADGRSVVADFGESRFVCQREDENLTKQPGNLRW 687
Query: 572 IAPEII-RDGIYDFRADIFSLGLMMIEI 598
+APE+ + G YD + D+FS L++ EI
Sbjct: 688 MAPEVFSQSGKYDRKVDVFSFALVIWEI 715
>At5g58940 [T] KOG1187 Serine/threonine protein kinase
Length = 466
Score = 74.3 bits (181), Expect = 6e-13
Identities = 66/218 (30%), Positives = 108/218 (49%), Gaps = 29/218 (13%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRIL----QEINMLSTI 448
T FS+V +G+G F TV++ + G AIK R K+N+ L EI LS I
Sbjct: 140 TANFSSVHQIGEGGFGTVFKGKLDD-GTIVAIKRAR--KNNYGKSWLLEFKNEIYTLSKI 196
Query: 449 QDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIA-KQQRLEDWRI 507
+ +V+ H I+ E+ NGNL +EH+ + RLE
Sbjct: 197 EHM---------NLVKLYGFLEHGDEKVIVVEYVANGNL----REHLDGLRGNRLEMAER 243
Query: 508 WKIIVEICLALRFIHD--SCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDK---- 561
+I +++ AL ++H I+H D+K +N+LIT + K+ADFG A +L ED
Sbjct: 244 LEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRAKVADFGFA-RLVSEDLGATH 302
Query: 562 -SFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
S + +G Y+ P+ +R ++D++S G++++EI
Sbjct: 303 ISTQVKGSAGYVDPDYLRTFQLTDKSDVYSFGVLLVEI 340
>At3g55450 [T] KOG1187 Serine/threonine protein kinase
Length = 392
Score = 74.3 bits (181), Expect = 6e-13
Identities = 62/224 (27%), Positives = 107/224 (47%), Gaps = 32/224 (14%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPET---------GLKYAIKSVRPTKHNFTNRILQEIN 443
T F + S++G+G F V++ ET GL A+K + P L EIN
Sbjct: 61 TRNFRSDSVVGEGGFGCVFRGWLDETTLTPTKSSSGLVIAVKRLNPDGFQGHREWLTEIN 120
Query: 444 MLSTIQDSVTNDTEGKEYIVE-----FISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAK 498
L + S N + Y +E + + HKGS + NGN D ++
Sbjct: 121 YLGQL--SHPNLVKLIGYCLEDEQRLLVYEFMHKGS--LENHLFANGNKDFKPLSWIL-- 174
Query: 499 QQRLEDWRIWKIIVEICLALRFIH-DSCSIVHLDLKPANVLITFEGNLKLADFGMATKLP 557
RI K+ ++ L F+H D +++ D+K +N+L+ + N KL+DFG+A P
Sbjct: 175 -------RI-KVALDAAKGLAFLHSDPVKVIYRDIKASNILLDSDFNAKLSDFGLARDGP 226
Query: 558 IEDKSFENE---GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+ ++S+ + G Y APE + G + R+D++S G++++E+
Sbjct: 227 MGEQSYVSTRVMGTFGYAAPEYVSTGHLNARSDVYSFGVVLLEL 270
>At3g26940 [T] KOG1187 Serine/threonine protein kinase
Length = 432
Score = 74.3 bits (181), Expect = 6e-13
Identities = 55/212 (25%), Positives = 100/212 (46%), Gaps = 18/212 (8%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T F N S++G+G F TVY+ TG A+K + + L E+ MLS +
Sbjct: 71 TNSFRNESLIGRGGFGTVYKGRL-STGQNIAVKMLDQSGIQGDKEFLVEVLMLSLLHH-- 127
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
+V + ++ E+ G+++ + + +++ Q DW+ KI
Sbjct: 128 -------RNLVHLFGYCAEGDQRLVVYEYMPLGSVEDHLYD--LSEGQEALDWKTRMKIA 178
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--- 566
+ L F+H+ +++ DLK +N+L+ + KL+DFG+A P +D S +
Sbjct: 179 LGAAKGLAFLHNEAQPPVIYRDLKTSNILLDHDYKPKLSDFGLAKFGPSDDMSHVSTRVM 238
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G Y APE G ++DI+S G++++E+
Sbjct: 239 GTHGYCAPEYANTGKLTLKSDIYSFGVVLLEL 270
>At3g18810 [T] KOG1187 Serine/threonine protein kinase
Length = 700
Score = 74.3 bits (181), Expect = 6e-13
Identities = 55/211 (26%), Positives = 99/211 (46%), Gaps = 19/211 (9%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T FS ++G+G F V++ P G + A+KS++ E++++S +
Sbjct: 334 TQGFSQSRLLGQGGFGYVHKGILPN-GKEIAVKSLKAGSGQGEREFQAEVDIISRVHH-- 390
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
++V + G ++ EF N L+ H+ K ++ DW KI
Sbjct: 391 -------RFLVSLVGYCIAGGQRMLVYEFLPNDTLEF----HLHGKSGKVLDWPTRLKIA 439
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMA--TKLPIEDKSFENEG 567
+ L ++H+ C I+H D+K +N+L+ K+ADFG+A ++ + S G
Sbjct: 440 LGSAKGLAYLHEDCHPRIIHRDIKASNILLDESFEAKVADFGLAKLSQDNVTHVSTRIMG 499
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
Y+APE G R+D+FS G+M++E+
Sbjct: 500 TFGYLAPEYASSGKLTDRSDVFSFGVMLLEL 530
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 74.3 bits (181), Expect = 6e-13
Identities = 62/225 (27%), Positives = 103/225 (45%), Gaps = 29/225 (12%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVRP---TKHNFTNRILQEINMLSTIQDSVTNDTE 457
I G G +S V + + G YA+K + TK N T + E +L ++
Sbjct: 47 IYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHPG----- 101
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLA 517
IV+ ++ S Y+ E CE G L F Q I ++ RL + E+ A
Sbjct: 102 ----IVKLFFTFQDTQSLYMALESCEGGEL--FDQ---ITRKGRLSEDEARFYSAEVVDA 152
Query: 518 LRFIHDSCSIVHLDLKPANVLITFEGNLKLADFG--------MATKLP---IEDKSFENE 566
L +IH+ ++H D+KP N+L+T +G++K+ADFG T LP +DK+
Sbjct: 153 LEYIHNM-GLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFV 211
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANVILPDNGSAW 611
G Y+ PE++ F D+++LG + ++ + + S W
Sbjct: 212 GTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEW 256
>At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 546
Score = 74.3 bits (181), Expect = 6e-13
Identities = 52/198 (26%), Positives = 107/198 (53%), Gaps = 16/198 (8%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+ G + +++ T+ + AIK ++P + N N +L+E + I V +
Sbjct: 292 VASGSYGDLHRGTY--CSQEVAIKFLKPDRVN--NEMLREFSQEVFIMRKVRHKN----- 342
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
+V+F+ + + + I+TEF G++ F+ + A + + + K+ +++ + ++
Sbjct: 343 VVQFLGACTRSPTLCIVTEFMARGSIYDFLHKQKCAFKLQT----LLKVALDVAKGMSYL 398
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-GDREYIAPEIIRDG 580
H + +I+H DLK AN+L+ G +K+ADFG+A ++ IE E G ++APE+I
Sbjct: 399 HQN-NIIHRDLKTANLLMDEHGLVKVADFGVA-RVQIESGVMTAETGTYRWMAPEVIEHK 456
Query: 581 IYDFRADIFSLGLMMIEI 598
Y+ +AD+FS +++ E+
Sbjct: 457 PYNHKADVFSYAIVLWEL 474
>At1g76370 [T] KOG1187 Serine/threonine protein kinase
Length = 381
Score = 74.3 bits (181), Expect = 6e-13
Identities = 57/211 (27%), Positives = 102/211 (48%), Gaps = 16/211 (7%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T F +I+GKG F +VY+ ++G AIK + P H + E+ MLS
Sbjct: 72 TKNFREGNIIGKGGFGSVYKGRL-DSGQVVAIKQLNPDGHQGNQEFIVEVCMLSVFHHP- 129
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+V I + ++ E+ G+L+ + + + Q L + KI V
Sbjct: 130 --------NLVTLIGYCTSGAQRLLVYEYMPMGSLEDHLFD-LEPDQTPLSWYTRMKIAV 180
Query: 513 EICLALRFIHD--SCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE---G 567
+ ++H S S+++ DLK AN+L+ E ++KL+DFG+A P+ +++ + G
Sbjct: 181 GAARGIEYLHCKISPSVIYRDLKSANILLDKEFSVKLSDFGLAKVGPVGNRTHVSTRVMG 240
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
Y APE G ++DI+S G++++E+
Sbjct: 241 TYGYCAPEYAMSGRLTIKSDIYSFGVVLLEL 271
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 74.3 bits (181), Expect = 6e-13
Identities = 55/205 (26%), Positives = 100/205 (47%), Gaps = 21/205 (10%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVR-----PTKHNFTNRILQEINMLSTIQDSVTND 455
++G G F VY E+G A+K V P ++ QEI++LS ++
Sbjct: 405 LLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLRH----- 459
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+ IV++ S + YI E+ G++ +QE+ + + ++ +I
Sbjct: 460 ----QNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENAIRNYT-----QQIL 510
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPE 575
L ++H + VH D+K AN+L+ G +K+ADFGMA + + +G ++APE
Sbjct: 511 SGLAYLHAK-NTVHRDIKGANILVDPHGRVKVADFGMAKHITAQSGPLSFKGSPYWMAPE 569
Query: 576 IIRDGI-YDFRADIFSLGLMMIEIA 599
+I++ + DI+SLG ++E+A
Sbjct: 570 VIKNSNGSNLAVDIWSLGCTVLEMA 594
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 74.3 bits (181), Expect = 6e-13
Identities = 64/240 (26%), Positives = 112/240 (46%), Gaps = 14/240 (5%)
Query: 361 MTKLRNDPTHLQPPEKQRSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGL 420
+ KL+ P+ +P + N D T F+ + ++GKG F V +
Sbjct: 315 LLKLKQKPSQKKPMVMRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEE 374
Query: 421 KYAIKSVRPTKHNFTNRILQEINMLST-IQDSVTNDTEGKEYIVEFISSWSHKGSFYIMT 479
YAIK ++ + I+Q+ ++ T I+ V E ++V+ S + + +
Sbjct: 375 LYAIKILKK------DVIIQDDDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVM 428
Query: 480 EFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLI 539
E+ G+L IQ+ K+ + EI L F+H I++ DLK NVL+
Sbjct: 429 EYVNGGDLMFQIQQFGKFKEPVAVFYA-----AEIAAGLFFLHTK-GILYRDLKLDNVLL 482
Query: 540 TFEGNLKLADFGMATKLPIEDKSFENE-GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+G++K+ADFGM + + DK+ + G +YIAPEII Y D ++ G+++ E+
Sbjct: 483 DADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEM 542
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 74.3 bits (181), Expect = 6e-13
Identities = 59/203 (29%), Positives = 93/203 (45%), Gaps = 14/203 (6%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEY 461
+GKGQ V G K AIK + K + +L ++ I + + +
Sbjct: 24 LGKGQTGLVKLGVHCVIGKKVAIKIINREK--LSESVLMKVEREIAIMKLIDHP-----H 76
Query: 462 IVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFI 521
++ + +K Y++ E G L ++ K+ RL K +I AL F
Sbjct: 77 VLGLSDVYENKKYLYLILEHVSGGELFDYL-----VKKGRLTPKEARKFFRQIISALDFC 131
Query: 522 HDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRDGI 581
H S SI H DLKP N+L+ + N+K+ADFGMA+ P + G Y PE+IR
Sbjct: 132 H-SHSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEK 190
Query: 582 YDFR-ADIFSLGLMMIEIAANVI 603
YD R AD++S G+++ + +
Sbjct: 191 YDGRKADVWSCGVILYALLVGAL 213
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 73.9 bits (180), Expect = 8e-13
Identities = 55/204 (26%), Positives = 95/204 (45%), Gaps = 13/204 (6%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++GKG F V QV +T YA+K++R I+ + + T+ +
Sbjct: 344 FDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAY------IVSKCEVTHTLAERTVLA 397
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+IV S+ Y++ F G L +Q + R R I E+
Sbjct: 398 RVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQH-----EGRFSLARSRFYIAELL 452
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMA-TKLPIEDKSFENEGDREYIAP 574
AL +H +++ DLKP N+L+ ++G++ L DFG+ + DK+ G EY+AP
Sbjct: 453 CALDSLH-KLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAP 511
Query: 575 EIIRDGIYDFRADIFSLGLMMIEI 598
EI+ Y D ++LG+++ E+
Sbjct: 512 EILLGQGYTKTVDWWTLGILLYEM 535
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/207 (28%), Positives = 104/207 (49%), Gaps = 18/207 (8%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRIL-QEINMLSTIQDSVTN 454
+S S +G+G F VY+ T AIK V + +L QEI L+ ++ +
Sbjct: 18 YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPL-- 75
Query: 455 DTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEI 514
I +I++ S +I+ E+C G+ ++ + L + ++ II E+
Sbjct: 76 -------ITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYV---NGLPEEKVSFIIHEV 125
Query: 515 CLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAP 574
L L+++H+ I H D+K AN+L+ EG +KL DFG++ + K G ++AP
Sbjct: 126 TLGLKYLHEQRKI-HRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAP 184
Query: 575 EII---RDGIYDFRADIFSLGLMMIEI 598
E++ DG Y+ +ADI+SLG+ E+
Sbjct: 185 EVVCCEVDG-YNEKADIWSLGITTYEL 210
>SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 830
Score = 73.9 bits (180), Expect = 8e-13
Identities = 64/234 (27%), Positives = 108/234 (45%), Gaps = 42/234 (17%)
Query: 400 SIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGK 459
S +G+G F+ VY+ ET +IKSV K T ++L+ + +I + +
Sbjct: 18 SEIGRGSFAIVYKGKHTETNRVISIKSVLTKK--LTKKLLENLESEISILKEIRH----- 70
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQ----------------EHVIAKQQRLE 503
++VE I +++ E+C G+L FI+ +H + L
Sbjct: 71 VHVVELIDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPVYKAGLN 130
Query: 504 DWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLIT-------------FEGN-----L 545
+ + ++ AL+F+ S S++H D+KP N+L+ F G+ L
Sbjct: 131 ETLVRHFTQQLASALQFLR-SRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPML 189
Query: 546 KLADFGMATKLPIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
KLADFG A L + G Y+APEI+R YD +AD++S+G ++ E+A
Sbjct: 190 KLADFGFARYLQTSSMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLYEMA 243
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 73.9 bits (180), Expect = 8e-13
Identities = 58/217 (26%), Positives = 104/217 (47%), Gaps = 18/217 (8%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVR-PTKHNFTNRILQEINMLSTIQDSVTNDTEGK 459
++G+G F V + +A+K +R P + T +E +L+ ++
Sbjct: 9 MIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHP-------- 60
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALR 519
IV F S+ +G YI+ E+C+ G+L I++ K + + I ++CL +
Sbjct: 61 -NIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQ---KGKLFPEDMILNWFTQMCLGVN 116
Query: 520 FIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSF--ENEGDREYIAPEII 577
IH ++H D+K N+ +T G +KL DFG A +L +F G Y+ PEI
Sbjct: 117 HIHKK-RVLHRDIKSKNIFLTQNGKVKLGDFGSA-RLLSNPMAFACTYVGTPYYVPPEIW 174
Query: 578 RDGIYDFRADIFSLGLMMIEIAANVILPDNGSAWHKL 614
+ Y+ ++DI+SLG ++ E+ + P ++W L
Sbjct: 175 ENLPYNNKSDIWSLGCILYEL-CTLKHPFQANSWKNL 210
>CE04493 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 449
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/211 (28%), Positives = 106/211 (49%), Gaps = 24/211 (11%)
Query: 403 GKGQFSTVYQVTFPETGLKYAIKSVRPTK---HNFTNRI----LQEINMLSTIQDSVTND 455
G+GQ S VY++ + + +VR K + TN++ L+E+N++ N
Sbjct: 213 GEGQ-SAVYRLIYNGKLIARKDVAVRLPKGVDQDSTNKLMAKKLREVNVI--------NG 263
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTE-FCENGNLDAFIQEHVIAKQQ-RLEDWRIWKIIVE 513
+IV F + HK + F E L A + + KQ + ++ I +I+
Sbjct: 264 CAPCPFIVHFFGYYVHKYRDCVKIHIFMEEMALSASVLKTEALKQGGAIPEFVIGRIVCS 323
Query: 514 ICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIA 573
+ A+ F+ D I+H D+KP N+LI ++G +K+ DFG+ L + + G ++Y A
Sbjct: 324 VIHAMWFLKDRLQIIHRDIKPGNILIDYDGRVKICDFGICGILE-NSIAVSDTGCQQYTA 382
Query: 574 PEIIRDGI-----YDFRADIFSLGLMMIEIA 599
PEI+ G+ Y ++DI+SLG+ + E+A
Sbjct: 383 PEILVKGVSNSPGYSIKSDIWSLGITIFELA 413
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 73.9 bits (180), Expect = 8e-13
Identities = 54/204 (26%), Positives = 100/204 (48%), Gaps = 10/204 (4%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
FS I+G+G F VY +TG YA+K + K + + + + I S+ +
Sbjct: 191 FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCL--DKKRIKMKQGETLALNERIMLSLVST 248
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
+ +IV ++ + + G+L + +H + +Q + + E+
Sbjct: 249 GQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYAS-----EVI 303
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPE 575
L L +H+ +V+ DLKPAN+L+ G+++++D G+A + K + G Y+APE
Sbjct: 304 LGLEHMHNRF-VVYRDLKPANILLDENGHVRVSDLGLACDYS-KKKPHASVGTHGYMAPE 361
Query: 576 IIRDGI-YDFRADIFSLGLMMIEI 598
++ G+ YD AD FSLG M+ ++
Sbjct: 362 VLAKGVAYDSSADWFSLGCMLYKL 385
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 73.9 bits (180), Expect = 8e-13
Identities = 62/226 (27%), Positives = 106/226 (46%), Gaps = 23/226 (10%)
Query: 385 MKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQE 441
M+N LT K+ ++G+G F+ VY T AIK + + K +I +E
Sbjct: 1 MENKPSVLTDKYDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQIKRE 60
Query: 442 INMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQR 501
I+++ + +VE + K Y + E+C+ G L + +AK +
Sbjct: 61 ISVMRIARHP---------NVVELYEVMATKTRIYFVMEYCKGGELF-----NKVAKG-K 105
Query: 502 LEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDK 561
L D WK ++ A+ F H S + H D+KP N+L+ NLK++DFG++ + +
Sbjct: 106 LRDDVAWKYFYQLINAVDFCH-SREVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQ 164
Query: 562 S---FENEGDREYIAPEII-RDGIYDFRADIFSLGLMMIEIAANVI 603
G Y+APE+I R G +ADI+S G+++ + A +
Sbjct: 165 DGLLHTTCGTPAYVAPEVINRKGYDGTKADIWSCGVVLFVLLAGYL 210
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 73.9 bits (180), Expect = 8e-13
Identities = 77/272 (28%), Positives = 122/272 (44%), Gaps = 31/272 (11%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQEINMLSTIQDSVTNDTE 457
++G G F+ VY +TG A+K V + K ++I +EI+++ ++
Sbjct: 29 LLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHP------ 82
Query: 458 GKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDW-RIWKIIVEICL 516
IVE + K Y E G L A +AK + ED R++ ++
Sbjct: 83 ---NIVELHEVMASKSKIYFAMELVRGGELFA-----KVAKGRLREDVARVY--FQQLIS 132
Query: 517 ALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMAT---KLPIEDKSFENEGDREYIA 573
A+ F H S + H DLKP N+L+ EGNLK+ DFG++ L + G Y+A
Sbjct: 133 AVDFCH-SRGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVA 191
Query: 574 PEIIRDGIYD-FRADIFSLGLMMIEIAANVI--LPDN-GSAWHKLRSGDLSDAGRLSSAE 629
PE+I YD +AD++S G+++ + A + DN + + K+ GD G LSS
Sbjct: 192 PEVILKKGYDGAKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSS-- 249
Query: 630 IHSSSLFSNKKDHTNITDITTHETKIPAWVPK 661
+ L + D T IT + W K
Sbjct: 250 -DARRLVTKLLDPNPNTRITIEKVMDSPWFKK 280
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 73.9 bits (180), Expect = 8e-13
Identities = 61/260 (23%), Positives = 116/260 (44%), Gaps = 50/260 (19%)
Query: 378 RSINASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPT---KHNF 434
RS+ S + D F + + +G F V+ TG +AIK ++ + N
Sbjct: 872 RSLRTSPVHPRDRTSIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNA 931
Query: 435 TNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEH 494
IL E ++L +++ ++V F S++ + + Y++ E+ G+L + ++
Sbjct: 932 VESILAERDILINVRNP---------FVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNL 982
Query: 495 VIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMA- 553
LE+ + I E+ LAL ++H +VH DLKP N+LI +G++KL DFG++
Sbjct: 983 GC-----LEEDIVRVYIAEVVLALEYLHSE-GVVHRDLKPDNLLIAHDGHIKLTDFGLSK 1036
Query: 554 -------------------------TKLPIEDKSFENE------GDREYIAPEIIRDGIY 582
++L ++ E G +Y+APEI+ +
Sbjct: 1037 VGLINSTDDLAGPAVSGTSLLDEEESRLAASEEQLERRKKRSAVGTPDYLAPEILLGTGH 1096
Query: 583 DFRADIFSLGLMMIEIAANV 602
AD +S+G+++ E+ +
Sbjct: 1097 GATADWWSVGIILFELIVGI 1116
>At2g28930 [T] KOG1187 Serine/threonine protein kinase
Length = 412
Score = 73.9 bits (180), Expect = 8e-13
Identities = 70/280 (25%), Positives = 122/280 (43%), Gaps = 34/280 (12%)
Query: 335 SPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQPPEKQRSINASIMKNPDFHLTT 394
SP S + + S S++I T R + LQ P + A + T
Sbjct: 13 SPGASPKYMSSEANDSLGSKSSSVSIRTNPRTEGEILQSPNLKSFTFAELKA-----ATR 67
Query: 395 KFSNVSIMGKGQFSTVYQ---------VTFPETGLKYAIKSVRPTKHNFTNRILQEINML 445
F S++G+G F +V++ + P TG+ A+K + L E+N L
Sbjct: 68 NFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQDGWQGHQEWLAEVNYL 127
Query: 446 STIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLE-- 503
Q S N +V+ I ++ EF G+L+ H+ + +
Sbjct: 128 G--QFSHPN-------LVKLIGYCLEDEHRLLVYEFMPRGSLE----NHLFRRGSYFQPL 174
Query: 504 DWRI-WKIIVEICLALRFIHDS-CSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDK 561
W + K+ + L F+H++ S+++ D K +N+L+ E N KL+DFG+A P DK
Sbjct: 175 SWTLRLKVALGAAKGLAFLHNAETSVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPTGDK 234
Query: 562 SFENE---GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
S + G Y APE + G ++D++S G++++E+
Sbjct: 235 SHVSTRIMGTYGYAAPEYLATGHLTTKSDVYSYGVVLLEV 274
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 73.9 bits (180), Expect = 8e-13
Identities = 61/243 (25%), Positives = 111/243 (45%), Gaps = 22/243 (9%)
Query: 368 PTHLQPPEKQRSINASI---MKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAI 424
P PP S + I + P L+ + +G+GQF Y+ T G +YA
Sbjct: 54 PKPAPPPPPSTSSGSQIGPILNRPMIDLSALYDLHKELGRGQFGITYKCTDKSNGREYAC 113
Query: 425 KSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCEN 484
KS+ K + ++++ I +T G+ IVEF ++ K + +++ E C
Sbjct: 114 KSISKRK-LIRRKDIEDVRREVMILQHLT----GQPNIVEFRGAYEDKDNLHLVMELCSG 168
Query: 485 GNL-DAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITF-- 541
G L D I++ ++++ +R +V +C + +VH DLKP N L+
Sbjct: 169 GELFDRIIKKGSYSEKEAANIFRQIVNVVHVCHFM-------GVVHRDLKPENFLLVSNE 221
Query: 542 -EGNLKLADFGMATKLPIEDKSFEN-EGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIA 599
+ +K DFG++ + E K + + G Y+APE++ Y D++S G+M+ +
Sbjct: 222 EDSPIKATDFGLSVFIE-EGKVYRDIVGSAYYVAPEVLHRN-YGKEIDVWSAGVMLYILL 279
Query: 600 ANV 602
+ V
Sbjct: 280 SGV 282
>At1g28390 [T] KOG1187 Serine/threonine protein kinase
Length = 470
Score = 73.9 bits (180), Expect = 8e-13
Identities = 62/236 (26%), Positives = 111/236 (46%), Gaps = 19/236 (8%)
Query: 374 PEKQRSINASIMKNPDFHLTTK-FSNVSIMGKGQFSTVYQVTFPETGLKYAIK--SVRPT 430
PEK+ + + + T FS + +GKG VY+ + L A+K ++ T
Sbjct: 29 PEKRHPPKLRVFNYDELAVATNGFSANNFLGKGSHGRVYKAVLDDGKLLAAVKRTTITTT 88
Query: 431 KHNFTNRILQ---EINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNL 487
N N + Q EI +LS ++ + G Y V+ + + ++ E+ NG L
Sbjct: 89 VGNNNNNVSQVDNEIEILSRVRHRWMVNLIG--YCVDH-----RRKTKLLVVEYMPNGTL 141
Query: 488 DAFIQEHVIAKQQRLEDW-RIWKIIVEICLALRFIHDS-CSIVHLDLKPANVLITFEGNL 545
+ + RL W R K ++I +A+ +H + ++H D+K NVLI +GN
Sbjct: 142 HDQLHSRS-SLDSRLSSWNRRIKHALQIAIAVHALHTAETQVIHRDIKSCNVLIDGDGNA 200
Query: 546 KLADFGMATKLPIEDKSFE---NEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+LADFG+A ++D+ + G Y+ P + ++D+FS G++++EI
Sbjct: 201 RLADFGLALIGNVDDERLKYTPPAGTLGYLDPSYLAPADLTAKSDVFSFGILLLEI 256
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 73.9 bits (180), Expect = 8e-13
Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 20/202 (9%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRP---TKHNFTNRILQEINMLSTIQDSVTNDTEG 458
+G G F V V E+G+ YA K + K + ++ E N+L ++ T
Sbjct: 53 LGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNT----- 107
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
V I+S+ S Y++ G L + + K ++ + + ++ LAL
Sbjct: 108 ----VNLIASYKDFDSLYLVLPLIGGGELFTYHR-----KVRKFTEKQARFYAAQVFLAL 158
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
++H CS+++ DLKP N+++ G LK+ DFG A K +E ++ G EY+ PEII+
Sbjct: 159 EYLHH-CSLLYRDLKPENIMMDKNGYLKVTDFGFAKK--VETRTMTLCGTPEYLPPEIIQ 215
Query: 579 DGIYDFRADIFSLGLMMIEIAA 600
Y D ++ G+++ E A
Sbjct: 216 SKPYGTSVDWWAFGVLVFEFVA 237
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 73.9 bits (180), Expect = 8e-13
Identities = 63/258 (24%), Positives = 114/258 (43%), Gaps = 22/258 (8%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSV---RPTKHNFTNRILQEINMLSTIQDSVTNDTEG 458
+G+G+F VY + A+K + K ++L+EI + S ++
Sbjct: 59 LGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHP------- 111
Query: 459 KEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLAL 518
+I+ ++ + + Y+ E G L ++ A R ++ R K ++ AL
Sbjct: 112 --HILRLLTWFHDESRIYLALEIASEGELFKHLRG---APNHRFDEPRSAKYTYQVANAL 166
Query: 519 RFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
+ H + +++H DLKP N+L+T +LKLADFG + P +K G +Y+ PE++
Sbjct: 167 NYCHLN-NVIHRDLKPENILLTSTDDLKLADFGWSAHTP-NNKRRTLCGTLDYLPPEMVD 224
Query: 579 DGIYDFRADIFSLGLMMIEIAANVILPDNG---SAWHKLRSGDLSDAGRLSSA--EIHSS 633
YD D + LG++ E ++ S + K+R ++S LS E+
Sbjct: 225 GNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGG 284
Query: 634 SLFSNKKDHTNITDITTH 651
L K + D+ TH
Sbjct: 285 LLRKESKGRITLVDVMTH 302
>SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 903
Score = 73.6 bits (179), Expect = 1e-12
Identities = 55/181 (30%), Positives = 97/181 (53%), Gaps = 41/181 (22%)
Query: 447 TIQDSVTNDTEG---KEYIVEFISSWSHK-----GSFYIMTEFCENGNLDAFIQEHVIAK 498
+ Q S T+D EG K+ +E SS + + YI E+CE +L I++ +
Sbjct: 688 SFQYSNTSDKEGSSDKDSSIEEASSVKTQENGLNATLYIQMEYCEKLSLQDIIRDKIPVD 747
Query: 499 QQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPI 558
+ WR+++ I+E AL +IH S ++H DLKP N+ + N+KL DFG+AT
Sbjct: 748 EM----WRLFRQILE---ALAYIH-SRGMMHRDLKPGNIFLDENRNVKLGDFGLAT---- 795
Query: 559 EDKSFENEGDR------------------EYIAPEII--RDGI-YDFRADIFSLGLMMIE 597
E++++++ D+ Y+APE++ R+G+ YD + D++SLG+++ E
Sbjct: 796 ENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDAKVDMYSLGIILFE 855
Query: 598 I 598
+
Sbjct: 856 M 856
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 73.6 bits (179), Expect = 1e-12
Identities = 57/211 (27%), Positives = 105/211 (49%), Gaps = 25/211 (11%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDS---V 452
F+ +S++GKG F V YAIK + K F IL+ + ST + +
Sbjct: 683 FTFLSVLGKGNFGKVMLAELKSEKQLYAIKVL---KKEF---ILENDEVESTKSEKRVFL 736
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIV 512
+ E ++V S + + Y + +F G+L IQ+ +++ R
Sbjct: 737 VANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQFSRR------RAQFYAA 790
Query: 513 EICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE-----G 567
E+CLAL++ HD+ I++ DLK N+L++ +G++K+AD+G+ ED +N G
Sbjct: 791 EVCLALKYFHDN-GIIYRDLKLDNILLSPDGHVKVADYGLCK----EDMWHDNTTATFCG 845
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
E++APEI+ + Y D ++ G+++ ++
Sbjct: 846 TPEFMAPEILLEQQYTRSVDWWAFGVLIYQM 876
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 73.6 bits (179), Expect = 1e-12
Identities = 74/303 (24%), Positives = 134/303 (43%), Gaps = 45/303 (14%)
Query: 328 DQESSIFSPSPSKTNLQTPTKTSFDIGPDSLAIMTKLRNDPTHLQP---------PEKQR 378
D+ + + +K N+ K I D I+ D +H++ P K
Sbjct: 219 DKHHKLTTSGVTKMNITERCKPKTTIQTDKKHIIRPFIEDKSHVESIMTGKVTKVPVKAD 278
Query: 379 SIN------------ASIMKNPDFHLTTKFSNVSI-MGKGQFSTVYQ---VTFPETGL-- 420
S N A + + H ++ NV +G+G +VY V + G+
Sbjct: 279 SKNTLSRRMTDRQALAMLKDSVTSHDPVEYFNVKHKLGQGASGSVYLAKVVGGKQLGIFD 338
Query: 421 KYAIKSVRPTKHNFTNRILQEINML-STIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMT 479
AIKS+ IL EI ++ +I ++ Y+ F+ H +++
Sbjct: 339 SVAIKSIDLQCQTRKELILNEITVMRESIHPNIVT------YLDSFLVRERH---LWVVM 389
Query: 480 EFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLI 539
E+ G+L I++ +L + +I +I +E C ++ +H + +I+H D+K NVL+
Sbjct: 390 EYMNAGSLTDIIEK------SKLTEAQIARICLETCKGIQHLH-ARNIIHRDIKSDNVLL 442
Query: 540 TFEGNLKLADFGMATKLPIE-DKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
GN+K+ DFG +L +K G ++APE+++ Y + DI+SLG+M+IE+
Sbjct: 443 DNSGNIKITDFGFCARLSNRTNKRVTMVGTPYWMAPEVVKQNEYGTKVDIWSLGIMIIEM 502
Query: 599 AAN 601
N
Sbjct: 503 IEN 505
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 73.6 bits (179), Expect = 1e-12
Identities = 49/196 (25%), Positives = 97/196 (49%), Gaps = 16/196 (8%)
Query: 401 IMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTNDTEGKE 460
++G G+F V++ T TGL A K ++ + EIN+++ + S N
Sbjct: 496 VLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQL--SHVN------ 547
Query: 461 YIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALRF 520
+++ ++ K S ++ E+ + G L + + ++ L + + +IC + +
Sbjct: 548 -LIQLYDAFESKHSCTLVMEYVDGGELF----DRITDEKYHLTELDVVLFTRQICEGVHY 602
Query: 521 IHDSCSIVHLDLKPANVLITFEGN--LKLADFGMATKLPIEDKSFENEGDREYIAPEIIR 578
+H I+HLDLKP N+L + +K+ DFG+A + +K N G E++APE++
Sbjct: 603 LHQHY-ILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVN 661
Query: 579 DGIYDFRADIFSLGLM 594
F D++S+G++
Sbjct: 662 YEFVSFPTDMWSVGVI 677
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 73.6 bits (179), Expect = 1e-12
Identities = 54/226 (23%), Positives = 112/226 (48%), Gaps = 22/226 (9%)
Query: 381 NASIMKNPDFHLTT---KFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNR 437
N ++ NP+ T+ ++ + +GKG F + E IK + + + R
Sbjct: 153 NEIMITNPNPRATSAQNRYERIRTVGKGAFGSAVLYRRREDSSLVIIKEINMYDLDSSQR 212
Query: 438 --ILQEINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHV 495
L E+++LS I+ I+ + S+ +G I E+ + G L +
Sbjct: 213 RLALNEVSLLSRIEHP---------NIIAYYDSFEEEGVLMIEMEYADGGTLAQMLSR-- 261
Query: 496 IAKQQRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATK 555
Q L++ +I +++++C A+ ++H++ S++H DLK ANV +T + +K+ DFG++
Sbjct: 262 --TQNLLDEEQIGDMMIQMCSAVAYLHEN-SVLHRDLKTANVFLTRDSFVKIGDFGISKI 318
Query: 556 LPIEDKSFENE---GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+ E + + G YI+PE+ Y+ ++D+++LG ++ E+
Sbjct: 319 MGTETLAQGAKTVVGTPYYISPEMCSGVSYNEKSDMWALGCILYEM 364
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 73.6 bits (179), Expect = 1e-12
Identities = 53/212 (25%), Positives = 98/212 (46%), Gaps = 19/212 (8%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFT----NRILQEINMLSTIQDS 451
+ V ++G+G F + + H T N I E+N+L +Q
Sbjct: 4 YEKVRVVGRGAFGVCWLCRGKNDASHQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHP 63
Query: 452 VTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKII 511
+ I+ +I S+ I+ ++ E G L+ I + K + ++ K +
Sbjct: 64 L---------IIGYIDSFIMDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREYFPEKTV 114
Query: 512 VE----ICLALRFIHDSCSIVHLDLKPANVLITFEGN-LKLADFGMATKLPIEDKSFENE 566
++ I +AL +H +IVH DLKP N+L+ LKL+DFG++ +L + +
Sbjct: 115 LDYFTQILIALNHMHQK-NIVHRDLKPQNILMNRRKTVLKLSDFGISKELGTKSAASTVI 173
Query: 567 GDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
G Y++PEI Y+ ++D++SLG ++ E+
Sbjct: 174 GTPNYLSPEICESRPYNQKSDMWSLGCVLYEL 205
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 73.6 bits (179), Expect = 1e-12
Identities = 61/235 (25%), Positives = 109/235 (45%), Gaps = 11/235 (4%)
Query: 396 FSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSVTND 455
F + ++GKG F V T YAIK ++ + I+ + T+ ++
Sbjct: 193 FDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKK------DVIIAREEVAHTLTENRVLQ 246
Query: 456 TEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEIC 515
++ E S+ + EF G+L + V ++ + R EI
Sbjct: 247 RCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGSEIV 306
Query: 516 LALRFIHDSCSIVHLDLKPANVLITFEGNLKLADFGMA-TKLPIEDKSFENEGDREYIAP 574
LAL ++H + SIV+ DLK N+L+ +G++K+ADFG+ ++ DK+ G EY+AP
Sbjct: 307 LALGYLHAN-SIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAP 365
Query: 575 EIIRDGIYDFRADIFSLGLMMIEIAANVI---LPDNGSAWHKLRSGDLSDAGRLS 626
E++ D Y D + +G++M E+ + D+ + + +GDL +LS
Sbjct: 366 EVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLS 420
>At5g66790 [T] KOG1187 Serine/threonine protein kinase
Length = 622
Score = 73.6 bits (179), Expect = 1e-12
Identities = 55/214 (25%), Positives = 102/214 (46%), Gaps = 21/214 (9%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T FS+ +++G G + TVY FP + AIK ++ ++++ EI +LS++
Sbjct: 311 TDSFSDKNMLGTGAYGTVYAGEFPNSSC-VAIKRLKHKDTTSIDQVVNEIKLLSSVSHP- 368
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
+V + G +++ EF NG L +Q + Q W++ I
Sbjct: 369 --------NLVRLLGCCFADGEPFLVYEFMPNGTLYQHLQHE---RGQPPLSWQLRLAIA 417
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADF-----GMATKLPIEDKSFE 564
+ A+ +H S + I H D+K +N+L+ E N K++DF GM+T S
Sbjct: 418 CQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFNSKISDFGLSRLGMSTDFEASHISTA 477
Query: 565 NEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+G Y+ P+ +D ++D++S G++++EI
Sbjct: 478 PQGTPGYLDPQYHQDFQLSDKSDVYSFGVVLVEI 511
>At5g42120 [T] KOG1187 Serine/threonine protein kinase
Length = 691
Score = 73.6 bits (179), Expect = 1e-12
Identities = 59/218 (27%), Positives = 106/218 (48%), Gaps = 20/218 (9%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T+ F+ +I+G+G +TVY+ + P G A+K NR N +T ++
Sbjct: 363 TSGFNENAIVGQGASATVYRGSIPSIG-SVAVKRFDREHWPQCNR-----NPFTTEFTTM 416
Query: 453 TNDTEGKEYIVEFISSWSHKGS-FYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWK-- 509
T K +V+F W +G+ ++ E+ NG+L F+ + + WK
Sbjct: 417 TGYLRHKN-LVQF-QGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEIIVLSWKQR 474
Query: 510 --IIVEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMA-----TKLPIED 560
II+ + AL ++H+ C I+H D+K N+++ E N KL DFG+A + L
Sbjct: 475 VNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSALLAGR 534
Query: 561 KSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEI 598
+ G Y+APE + G+ + D++S G++++E+
Sbjct: 535 AATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEV 572
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 73.6 bits (179), Expect = 1e-12
Identities = 58/226 (25%), Positives = 103/226 (44%), Gaps = 17/226 (7%)
Query: 381 NASIMKNPDFHLTTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQ 440
N I+ P + + +G+GQF Y VT ET + A KS+ PT+ ++
Sbjct: 63 NGRILGRPMEEVRRTYEFGRELGRGQFGVTYLVTHKETKQQVACKSI-PTRRLVHKDDIE 121
Query: 441 EINMLSTIQDSVTNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNL-DAFIQEHVIAKQ 499
++ + + + G IV+ ++ + S ++ E CE G L D I + + +++
Sbjct: 122 DVRR----EVQIMHHLSGHRNIVDLKGAYEDRHSVNLIMELCEGGELFDRIISKGLYSER 177
Query: 500 QRLEDWRIWKIIVEICLALRFIHDSCSIVHLDLKPANVLITFEGN---LKLADFGMATKL 556
+ R ++V C S ++H DLKP N L + LK DFG++
Sbjct: 178 AAADLCRQMVMVVHSC-------HSMGVMHRDLKPENFLFLSKDENSPLKATDFGLSVFF 230
Query: 557 PIEDKSFENEGDREYIAPEIIRDGIYDFRADIFSLGLMMIEIAANV 602
DK + G Y+APE+++ Y ADI+S G+++ + + V
Sbjct: 231 KPGDKFKDLVGSAYYVAPEVLKRN-YGPEADIWSAGVILYILLSGV 275
>At2g42960 [T] KOG1187 Serine/threonine protein kinase
Length = 494
Score = 73.6 bits (179), Expect = 1e-12
Identities = 56/210 (26%), Positives = 101/210 (47%), Gaps = 17/210 (8%)
Query: 393 TTKFSNVSIMGKGQFSTVYQVTFPETGLKYAIKSVRPTKHNFTNRILQEINMLSTIQDSV 452
T +F+ V+++G+G + VY+ G + A+K + E+ + ++
Sbjct: 180 TNRFAPVNVLGEGGYGVVYRGKLVN-GTEVAVKKLLNNLGQAEKEFRVEVEAIGHVRHK- 237
Query: 453 TNDTEGKEYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRI-WKII 511
N Y +E + H+ Y E+ +GNL+ ++ H +Q W KII
Sbjct: 238 -NLVRLLGYCIEGV----HRMLVY---EYVNSGNLEQWL--HGAMRQHGNLTWEARMKII 287
Query: 512 VEICLALRFIHDSCS--IVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENE--G 567
AL ++H++ +VH D+K +N+LI E N KL+DFG+A L + G
Sbjct: 288 TGTAQALAYLHEAIEPKVVHRDIKASNILIDDEFNAKLSDFGLAKLLDSGESHITTRVMG 347
Query: 568 DREYIAPEIIRDGIYDFRADIFSLGLMMIE 597
Y+APE G+ + ++DI+S G++++E
Sbjct: 348 TFGYVAPEYANTGLLNEKSDIYSFGVLLLE 377
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 73.6 bits (179), Expect = 1e-12
Identities = 61/218 (27%), Positives = 105/218 (47%), Gaps = 19/218 (8%)
Query: 402 MGKGQFSTVYQVTFPETGLKYAIKSVRPTKHN--FTNRILQEINMLSTIQDSVTNDTEGK 459
+GKG F+ V T T K AIK + T N + N+ +EI +L +++
Sbjct: 47 IGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFREIAILKSLRHP-------- 98
Query: 460 EYIVEFISSWSHKGSFYIMTEFCENGNLDAFIQEHVIAKQQRLEDWRIWKIIVEICLALR 519
+I + Y++TE+ NG I +H++A R+++ ++ ++ A+
Sbjct: 99 -HITRLYEVMESQSMIYLVTEYAPNGE----IFDHLVANG-RMKEPEAARVFTQLVSAVH 152
Query: 520 FIHDSCSIVHLDLKPANVLITFEGNLKLADFGMATKLPIEDKSFENEGDREYIAPEIIRD 579
+ H +VH DLK NVL+ + N+KLADFG + G Y APE+ +
Sbjct: 153 YCHRR-GVVHRDLKAENVLLDKDMNIKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQG 211
Query: 580 GIYDF-RADIFSLGLMMIEIAANVILPDNGSAWHKLRS 616
YD ++DI+SLG+++ + LP +G +L+S
Sbjct: 212 LEYDGPKSDIWSLGVVLYALVCGA-LPFDGKTILELKS 248
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,414,340
Number of Sequences: 60738
Number of extensions: 1711592
Number of successful extensions: 7441
Number of sequences better than 1.0e-05: 1363
Number of HSP's better than 0.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 1313
Number of HSP's that attempted gapping in prelim test: 5496
Number of HSP's gapped (non-prelim): 1587
length of query: 722
length of database: 30,389,216
effective HSP length: 114
effective length of query: 608
effective length of database: 23,465,084
effective search space: 14266771072
effective search space used: 14266771072
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)