ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1906 good H KOG1284 Coenzyme transport and metabolism Bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2butanone-4-phosphate synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1906 680135 679509 -209
(209 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR487c [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihydr... 279 2e-75
SPBC23E6.06c [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-d... 248 4e-66
At5g64300 [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihy... 187 9e-48
At2g22450 [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihy... 176 2e-44
At5g59750 [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihy... 155 4e-38
>YDR487c [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 208
Score = 279 bits (714), Expect = 2e-75
Identities = 140/208 (67%), Positives = 165/208 (79%), Gaps = 2/208 (0%)
Query: 2 IFTDIEVAIEKFRQNKFVIVMDDESRENEGDLICAANAITTEQMAFLIRYSSGYVCAPMT 61
+FT I+ AIE F+QNKFVIVMDD RENEGDLICAA ++TEQMAFL+R+SSGYVCAPMT
Sbjct: 1 MFTPIDQAIEHFKQNKFVIVMDDAGRENEGDLICAAENVSTEQMAFLVRHSSGYVCAPMT 60
Query: 62 NEWADRLDLPLLKD-LSCESYADDRHGTAYTITCDYAHGTTTGISAHDRALTCSKLADKT 120
N AD+LDLPLL+ + ES DDRHGTAYTIT D A GTTTGISAHDR++TC LAD +
Sbjct: 61 NAIADKLDLPLLRTGMKFESNDDDRHGTAYTITVDVAQGTTTGISAHDRSMTCRALADSS 120
Query: 121 TTAIDYLKPGHVVPLRAKEGGVLARRGHTEAAVDLCKLASLPPVGVIGELVK-DEDGDMM 179
+T +LKPGH+ PLRA +GGVL RRGHTEA VDLCKL+ L PV VIGELV DE G MM
Sbjct: 121 STPKSFLKPGHICPLRAADGGVLQRRGHTEAGVDLCKLSGLSPVAVIGELVNDDEQGTMM 180
Query: 180 RLDDCVEFGKEFDISIITLEALVDYIQK 207
RL+DC FGK+ I +I++E L Y++K
Sbjct: 181 RLNDCQAFGKKHGIPLISIEELAQYLKK 208
>SPBC23E6.06c [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 204
Score = 248 bits (633), Expect = 4e-66
Identities = 123/206 (59%), Positives = 158/206 (75%), Gaps = 6/206 (2%)
Query: 2 IFTDIEVAIEKFRQNKFVIVMDDESRENEGDLICAANAITTEQMAFLIRYSSGYVCAPMT 61
+ IE A+ FR KF+IV+DDE+RENEGDLI A +TTEQMAFL+R+SSGYVC PMT
Sbjct: 1 MLASIEEAVNDFRDGKFLIVLDDETRENEGDLIIAGCKVTTEQMAFLVRHSSGYVCVPMT 60
Query: 62 NEWADRLDLPLLKDLSCESYADDRHGTAYTITCDYAHGTTTGISAHDRALTCSKLAD-KT 120
E D L++P++ D + +DR TAY +T DYA+GTTTGISAHDRALT +LA+ +
Sbjct: 61 GERLDSLEIPMMVDNN-----EDRMRTAYAVTLDYANGTTTGISAHDRALTTRQLANPEV 115
Query: 121 TTAIDYLKPGHVVPLRAKEGGVLARRGHTEAAVDLCKLASLPPVGVIGELVKDEDGDMMR 180
T+ ++ +PGH+VPLRA++GGVL R GHTEAAVDLCKLA LPPVG I ELV++EDG M R
Sbjct: 116 TSPREFNRPGHIVPLRARDGGVLERDGHTEAAVDLCKLAGLPPVGAICELVREEDGLMSR 175
Query: 181 LDDCVEFGKEFDISIITLEALVDYIQ 206
DDC+ FGK++ I +IT+E+L YI+
Sbjct: 176 FDDCISFGKKWGIKVITIESLKSYIK 201
>At5g64300 [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 543
Score = 187 bits (475), Expect = 9e-48
Identities = 97/205 (47%), Positives = 135/205 (65%), Gaps = 4/205 (1%)
Query: 3 FTDIEVAIEKFRQNKFVIVMDDESRENEGDLICAANAITTEQMAFLIRYSSGYVCAPMTN 62
F+ I AIE RQ K V+V+DDE RENEGDL+ AA T E MAF++R+ +G VC M
Sbjct: 128 FSSIPEAIEDIRQGKLVVVVDDEDRENEGDLVMAAQLATPEAMAFIVRHGTGIVCVSMKE 187
Query: 63 EWADRLDLPLLKDLSCESYADDRHGTAYTITCDYAHGTTTGISAHDRALTCSKLADKTTT 122
+ +RL LPL+ + + +++ TA+T+T D HGTTTG+SA DRA T LA + +
Sbjct: 188 DDLERLHLPLMVN---QKENEEKLSTAFTVTVDAKHGTTTGVSARDRATTILSLASRDSK 244
Query: 123 AIDYLKPGHVVPLRAKEGGVLARRGHTEAAVDLCKLASLPPVGVIGELVKDEDGDMMRLD 182
D+ +PGH+ PL+ +EGGVL R GHTEA+VDL LA L PVGV+ E+V D+DG M RL
Sbjct: 245 PEDFNRPGHIFPLKYREGGVLKRAGHTEASVDLTVLAGLDPVGVLCEIV-DDDGSMARLP 303
Query: 183 DCVEFGKEFDISIITLEALVDYIQK 207
EF E ++ ++++ L+ Y +K
Sbjct: 304 KLREFAAENNLKVVSIADLIRYRRK 328
>At2g22450 [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 433
Score = 176 bits (447), Expect = 2e-44
Identities = 95/207 (45%), Positives = 133/207 (63%), Gaps = 4/207 (1%)
Query: 3 FTDIEVAIEKFRQNKFVIVMDDESRENEGDLICAANAITTEQMAFLIRYSSGYVCAPMTN 62
F I AIE R K V+V+DDE RENEGDLI AA+ T E MAF++++ +G VC M
Sbjct: 63 FASIPQAIEDIRHGKMVVVVDDEDRENEGDLIMAASLATPEAMAFVVKHGTGIVCVSMKG 122
Query: 63 EWADRLDLPLLKDLSCESYADDRHGTAYTITCDYAHGTTTGISAHDRALTCSKLADKTTT 122
E +RL+LPL+ +++ TA+T++ D GT+TG+SA DRA T LA K +
Sbjct: 123 EDLERLELPLMVTRKDN---EEKLRTAFTVSVDAKKGTSTGVSARDRAQTILTLASKDSK 179
Query: 123 AIDYLKPGHVVPLRAKEGGVLARRGHTEAAVDLCKLASLPPVGVIGELVKDEDGDMMRLD 182
D+ +PGH+ PLR +EGGVL R GHTEA+VDL LA L PV V+ E+V D+DG M RL
Sbjct: 180 PEDFNRPGHIFPLRYREGGVLKRAGHTEASVDLTVLAGLEPVSVLCEIV-DDDGSMARLP 238
Query: 183 DCVEFGKEFDISIITLEALVDYIQKHQ 209
+F +E ++ +I++ L+ Y +K +
Sbjct: 239 RLRQFAQENNLKLISIADLIRYRRKRE 265
>At5g59750 [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 508
Score = 155 bits (392), Expect = 4e-38
Identities = 87/205 (42%), Positives = 124/205 (60%), Gaps = 3/205 (1%)
Query: 3 FTDIEVAIEKFRQNKFVIVMDDESRENEGDLICAANAITTEQMAFLIRYSSGYVCAPMTN 62
++ IE+A++ R+ KFVIV+DDE+ + EG+LI AA + + +AFLI+ SG V M
Sbjct: 100 YSSIELALQALRKGKFVIVVDDETGDVEGNLIMAATLTSPKDIAFLIKNGSGIVSVGMKK 159
Query: 63 EWADRLDLPLLKDLSCESYADDRHGTAYTITCDYAHGTTTGISAHDRALTCSKLADKTTT 122
E +RL L L+ S E +D +TIT D GT+TG+SA DRA+T L+
Sbjct: 160 ENLERLSLTLM---SPEMEDEDSSAPTFTITVDAKSGTSTGVSASDRAMTVLALSSLDAK 216
Query: 123 AIDYLKPGHVVPLRAKEGGVLARRGHTEAAVDLCKLASLPPVGVIGELVKDEDGDMMRLD 182
D+ +PGHV PL+ ++GGVL R GHTEA+VDL LA L P+ V+ ++ EDG M L
Sbjct: 217 PDDFRRPGHVFPLKYRDGGVLRRAGHTEASVDLMILAGLRPLSVLSAILDQEDGSMASLP 276
Query: 183 DCVEFGKEFDISIITLEALVDYIQK 207
+ E DI I++L L+ Y +K
Sbjct: 277 YMKKLATEHDIPIVSLTDLIRYRRK 301
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,774,997
Number of Sequences: 60738
Number of extensions: 524500
Number of successful extensions: 992
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 978
Number of HSP's gapped (non-prelim): 5
length of query: 209
length of database: 30,389,216
effective HSP length: 102
effective length of query: 107
effective length of database: 24,193,940
effective search space: 2588751580
effective search space used: 2588751580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)