ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1909 good I KOG3071 Lipid transport and metabolism Fatty acyl-CoA elongase/Polyunsaturated fatty acid specific elongation enzyme
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1909 682191 681166 -342
(342 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR372w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 389 e-108
YCR034w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 236 5e-62
YJL196c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 226 5e-59
SPAC1B2.03c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated ... 223 3e-58
SPAC806.09c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated ... 184 2e-46
At3g06460 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fa... 72 2e-12
CE10286 [I] KOG3072 Long chain fatty acid elongase 67 3e-11
7300877 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 66 8e-11
At3g06470 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fa... 64 3e-10
7299265 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 62 9e-10
7300874 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 61 3e-09
CE05979 [I] KOG3072 Long chain fatty acid elongase 60 4e-09
7294765 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 60 6e-09
7299267 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 59 1e-08
7300878 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 57 4e-08
CE10284 [I] KOG3072 Long chain fatty acid elongase 57 5e-08
7299266 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 57 5e-08
7299264 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 57 5e-08
CE19785 [I] KOG3072 Long chain fatty acid elongase 56 7e-08
7302565 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 55 2e-07
Hs18561450 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 54 4e-07
Hs12232379 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 54 4e-07
Hs8923312 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fa... 53 6e-07
7296847 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatt... 52 1e-06
Hs13129088 [I] KOG3072 Long chain fatty acid elongase 52 2e-06
CE00112 [I] KOG3072 Long chain fatty acid elongase 51 2e-06
Hs13489093 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated f... 51 3e-06
Hs17454617 [I] KOG3072 Long chain fatty acid elongase 50 6e-06
>YLR372w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 345
Score = 389 bits (998), Expect = e-108
Identities = 187/312 (59%), Positives = 223/312 (70%), Gaps = 3/312 (0%)
Query: 10 QVLDNLNGCSWIEYDIPSPERPFGLHLWPIFSKAFEYVKGYPADEFEFVHNKTFMANGXX 69
Q L++ + C +++ +PS E PFG+ LWPIFSK FEY GYPA++FEF+HNKTF+ANG
Sbjct: 17 QSLNSSSSC-FLKVHVPSIENPFGIELWPIFSKVFEYFSGYPAEQFEFIHNKTFLANGYH 75
Query: 70 XXXXXXXXXXXXFGGQALLRKANAAPLKLNFLFQLHNXXXXXXXXXXXXXMVEQIFPMIW 129
FGGQA+LR NA+PLK LF++HN M+EQ+ PM++
Sbjct: 76 AVSIIIVYYIIIFGGQAILRALNASPLKFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVY 135
Query: 130 NHGLFWSICSKEAFAPXXXXXXXXXXXXXXXXXXDTVXXXXXXXXXXXXHTYHHGATALL 189
++GLFWSICSKEAFAP DTV HTYHHGATALL
Sbjct: 136 HNGLFWSICSKEAFAPKLVTLYYLNYLTKFVELIDTVFLVLRRKKLLFLHTYHHGATALL 195
Query: 190 CYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRVWWKEWVTRFQIIQFLIDLVFV 249
CY+QL G+TS+EWVVI LNLGVHV+MYWYYFLS+ GIRVWWK+WVTRFQIIQFLIDLVFV
Sbjct: 196 CYTQLIGRTSVEWVVILLNLGVHVIMYWYYFLSSCGIRVWWKQWVTRFQIIQFLIDLVFV 255
Query: 250 YFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSYRKGASK-- 307
YFATYTFYA+KY D ILPNKGTCYGT++AAAYGYLILTSYL+LFISFYIQSY+KG K
Sbjct: 256 YFATYTFYAHKYLDGILPNKGTCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGGKKTV 315
Query: 308 KGETENKNAAAA 319
K E+E + A+
Sbjct: 316 KKESEVSGSVAS 327
>YCR034w [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 347
Score = 236 bits (601), Expect = 5e-62
Identities = 129/286 (45%), Positives = 163/286 (56%), Gaps = 6/286 (2%)
Query: 25 IPSPERPF-GLHLWPIFSKAFEYVKG--YPADEFEFVHNKTFMANGXXXXXXXXXXXXXX 81
+P+ ERPF + LW F V + EF+F+ + ++
Sbjct: 23 LPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVII 82
Query: 82 FGGQALLRKANAAPLKLNFLFQLHNXXXXXXXXXXXXXMVEQIFPMIWNHGLFWSICSKE 141
FGG+ LL K+ P KLN LFQLHN MVEQ+ P+I HGL+++IC+
Sbjct: 83 FGGRFLLSKSK--PFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIG 140
Query: 142 AFAPXXXXXXXXXXXXXXXXXXDTVXXXXXXXXXXXXHTYHHGATALLCYSQLQGKTSIE 201
A+ DT HTYHHGATALLCY+QL G TSI
Sbjct: 141 AWTQPLVTLYYMNYIVKFIEFIDTFFLVLKHKKLTFLHTYHHGATALLCYTQLMGTTSIS 200
Query: 202 WVVIALNLGVHVVMYWYYFLSARGIRVWWKEWVTRFQIIQFLIDLVFVYFATYTFYANKY 261
WV I+LNLGVHVVMYWYYFL+ARGIRVWWKEWVTRFQIIQF++D+ F+YFA Y + Y
Sbjct: 201 WVPISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLY 260
Query: 262 FDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSYRKGASK 307
F ILP+ G C G+ +A G I++SYLVLFISFYI Y++ +K
Sbjct: 261 F-PILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKGTK 305
>YJL196c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 310
Score = 226 bits (575), Expect = 5e-59
Identities = 117/294 (39%), Positives = 164/294 (54%), Gaps = 6/294 (2%)
Query: 26 PSPERPF-GLHLWPIFSKAFEYVKG--YPADEFEFVHNKTFMANGXXXXXXXXXXXXXXF 82
P+ +RPF ++LW F++A + + +FEF K ++ F
Sbjct: 18 PTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIF 77
Query: 83 GGQALLRKANAAPLKLNFLFQLHNXXXXXXXXXXXXXMVEQIFPMIWNHGLFWSICSKEA 142
GG++L++ PLKL F+ Q+HN MVEQ+ P+++ HGL++++C+ E+
Sbjct: 78 GGRSLVKSCK--PLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVES 135
Query: 143 FAPXXXXXXXXXXXXXXXXXXDTVXXXXXXXXXXXXHTYHHGATALLCYSQLQGKTSIEW 202
+ DTV HTYHHGATALLCY+QL G T++ W
Sbjct: 136 WTQPMETLYYLNYMTKFVEFADTVLMVLKHRKLTFLHTYHHGATALLCYNQLVGYTAVTW 195
Query: 203 VVIALNLGVHVVMYWYYFLSARGIRVWWKEWVTRFQIIQFLIDLVFVYFATYTFYANKYF 262
V + LNL VHV+MYWYYFLSA GIRVWWK WVTR QI+QF++DL+ VY+ Y YF
Sbjct: 196 VPVTLNLAVHVLMYWYYFLSASGIRVWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYF 255
Query: 263 DD-ILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSYRKGASKKGETENKN 315
+ P C G+ +A A G ILTSYL LFISFYI+ Y++G++ + NKN
Sbjct: 256 KNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRGSASGKKKINKN 309
>SPAC1B2.03c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 334
Score = 223 bits (568), Expect = 3e-58
Identities = 122/312 (39%), Positives = 165/312 (52%), Gaps = 9/312 (2%)
Query: 14 NLNGCSWIEYDIPSPERPFGLHLWPIFSKAFEYVKGYPADEFEFVHNKTFMANGXXXXXX 73
+L G ++ PS + PFG+ LW +F + G+ EFE++ KT M+
Sbjct: 2 DLTGAHMLKIHRPSIDHPFGVDLWHLFEQLSIKTIGWNPSEFEYIPGKTPMSQWSSVIVS 61
Query: 74 XXXXXXXXFGGQALLRKANAAPLKLNFLFQLHNXXXXXXXXXXXXXMVEQIFPMIWNHGL 133
G+A++ N PLK LFQLHN +VE++F +GL
Sbjct: 62 ITAYYVIILSGRAIM--TNRKPLKQRRLFQLHNFILTIISGALLALLVEEVFRNYMRNGL 119
Query: 134 FWSICSKEAFAPXXXXXXXXXXXXXXXXXXDTVXXXXXXXXXXXXHTYHHGATALLCYSQ 193
F+ +C F DTV H YHHG TALLC++Q
Sbjct: 120 FYCVCDSRHFTQRLVTLYYLNYLTKYLELMDTVFLFLKKKPLAFLHCYHHGITALLCFTQ 179
Query: 194 LQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRVWWKEWVTRFQIIQFLIDLVFVYFAT 253
L G+TS++W VI LNL VHV+MY YYFL+A G RVWWK+WVTR QIIQF++DL+ YF T
Sbjct: 180 LLGRTSVQWGVIGLNLYVHVIMYSYYFLAACGRRVWWKQWVTRVQIIQFVLDLILCYFGT 239
Query: 254 YTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSYRKGASKK----- 308
Y+ A +YF LP+ G C G+ AA +G +L+SYL LFI FYI +Y K +KK
Sbjct: 240 YSHIAFRYF-PWLPHVGDCSGSLFAAFFGCGVLSSYLFLFIGFYINTYIKRGAKKNQRKA 298
Query: 309 -GETENKNAAAA 319
G+ +N + AAA
Sbjct: 299 AGKADNTSVAAA 310
>SPAC806.09c [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 328
Score = 184 bits (466), Expect = 2e-46
Identities = 106/288 (36%), Positives = 148/288 (50%), Gaps = 10/288 (3%)
Query: 34 LHLWPIFSKAFEYVKGYPADEFEFVHNKTFMANGXXXXXXXXXXXXXXFGGQALLRKANA 93
L W + + G FEF+ NKT ++ G ++R N
Sbjct: 2 LDCWSWLNSLADATFGKRPSSFEFIVNKTRFSSAPVVATIIISYYLLILVGGRIMR--NR 59
Query: 94 APLKLNFLFQLHNXXXXXXXXXXXXXMVEQIFPMIWNHGLFWSICSKEAFAPXXXXXXXX 153
P++L +FQ +N + EQ+ P I+ HG F+SIC+++A+
Sbjct: 60 QPIRLQKIFQYYNLTFSIASAILALLIFEQVAPAIYKHGFFFSICNEKAWTQPLVFLYYC 119
Query: 154 XXXXXXXXXXDTVXXXXXXXXXXXXHTYHHGATALLCYSQLQGKTSIEWVVIALNLGVHV 213
DT H YHHGATA+L Y+Q+ G+TSI W++I +NL VHV
Sbjct: 120 AYISKFLELTDTFFLVLRKKPLQFLHCYHHGATAVLVYTQIVGRTSISWLIIEINLLVHV 179
Query: 214 VMYWYYFLSARGIRVWWKEWVTRFQIIQFLIDLVFVYFATYT--FYANKYFDDILPNKGT 271
MY+YY+L A+GIRV WK+WVTRFQI+QF DL F+YFA YT Y K++ + G
Sbjct: 180 TMYYYYYLVAKGIRVPWKKWVTRFQIVQFFADLGFIYFAVYTEVAYRLKFYKACM---GH 236
Query: 272 CYGTESAAAYGYLILTSYLVLFISFYIQSYRKGASKKGETENKNAAAA 319
C G AA G ++SYLVLFI FY +Y+K A+ K + + AAAA
Sbjct: 237 CSGHPLAAFCGLATISSYLVLFIVFYHNTYKKNAALKMKAK---AAAA 281
>At3g06460 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 298
Score = 71.6 bits (174), Expect = 2e-12
Identities = 43/125 (34%), Positives = 59/125 (46%), Gaps = 10/125 (8%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRVWWKEWVTRFQ 238
H YHH +LCY L+ + S+ V + LN VHV+MY YYFL A G R WK+ VT FQ
Sbjct: 151 HVYHHATVVILCYLWLRTRQSMFPVGLVLNSTVHVIMYGYYFLCAIGSRPKWKKLVTNFQ 210
Query: 239 IIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYI 298
++QF + YF T Y + + S L LF +F+
Sbjct: 211 MVQFAFGM---GLGAAWMLPEHYFGSGCAGIWTVY-------FNGVFTASLLALFYNFHS 260
Query: 299 QSYRK 303
++Y K
Sbjct: 261 KNYEK 265
>CE10286 [I] KOG3072 Long chain fatty acid elongase
Length = 274
Score = 67.4 bits (163), Expect = 3e-11
Identities = 42/138 (30%), Positives = 61/138 (43%), Gaps = 12/138 (8%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRV--WWKEWVTR 236
H YHH T + + + +N VH +MY YY L + G++V W + +T
Sbjct: 141 HWYHHVLTMNYAFMSFEANLGFNTWITWMNFSVHSIMYGYYMLRSFGVKVPAWIAKNITT 200
Query: 237 FQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISF 296
QI+QF+I ++ Y + D T + L+ SY+VLF +F
Sbjct: 201 MQILQFVITHFILFHVGYLAVTGQSVD----------STPGYYWFCLLMEISYVVLFGNF 250
Query: 297 YIQSYRKGASKKGETENK 314
Y QSY KG KK E K
Sbjct: 251 YYQSYIKGGGKKFNAEKK 268
>7300877 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 322
Score = 65.9 bits (159), Expect = 8e-11
Identities = 44/146 (30%), Positives = 73/146 (49%), Gaps = 20/146 (13%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIA-LNLGVHVVMYWYYFLSARGIR----VWWKEW 233
H YHH T L + L+ + V+I LN GVH++MY+YY ++A G + +WWK++
Sbjct: 145 HVYHHTITVLFSWGYLKYAPGEQGVIIGILNSGVHIIMYFYYMVAAMGPQYQKYLWWKKY 204
Query: 234 VTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLF 293
+T Q+IQF+ L+ Y T + KG C ++ + +L LF
Sbjct: 205 MTSIQLIQFV--LILGYMLT------------VGAKG-CNMPKTLTFFFVGNTVIFLYLF 249
Query: 294 ISFYIQSYRKGASKKGETENKNAAAA 319
+FY ++Y+K S G + ++ A
Sbjct: 250 GNFYRKTYKKAKSVDGGSRTTGSSLA 275
>At3g06470 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 278
Score = 63.9 bits (154), Expect = 3e-10
Identities = 29/65 (44%), Positives = 39/65 (59%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRVWWKEWVTRFQ 238
H YHH ++CY L+ + S+ + + N VHV+MY YYFL A G R WK VT Q
Sbjct: 154 HVYHHATVVVMCYLWLRTRQSMFPIALVTNSTVHVIMYGYYFLCAVGSRPKWKRLVTDCQ 213
Query: 239 IIQFL 243
I+QF+
Sbjct: 214 IVQFV 218
>7299265 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 257
Score = 62.4 bits (150), Expect = 9e-10
Identities = 46/143 (32%), Positives = 66/143 (45%), Gaps = 21/143 (14%)
Query: 179 HTYHHGATALLCYSQ--LQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRV----WWKE 232
H +HH A A Y G + + LN VHV+MY YY+LS+ V WWK+
Sbjct: 130 HVFHHFAMAFFGYLYYCFHGYGGVAFPQCLLNTAVHVIMYAYYYLSSISKEVQRSLWWKK 189
Query: 233 WVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVL 292
++T Q++QF I L+ T T + N+ YG S +A+ + V+
Sbjct: 190 YITIAQLVQFAIILL---HCTITLAQ----PNCAVNRPLTYGCGSLSAF-------FAVI 235
Query: 293 FISFYIQSYRKGASKKGETENKN 315
F FY +Y K KK +NKN
Sbjct: 236 FSQFYYHNYIK-PGKKSAKQNKN 257
>7300874 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 277
Score = 60.8 bits (146), Expect = 3e-09
Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 19/141 (13%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIA-LNLGVHVVMYWYYFLSARGIRV----WWKEW 233
H YHH + + ++ ++ +N +H++MY YY LSA G +V WWK++
Sbjct: 149 HLYHHTLMPVCAFIGVKYFAGGHGTLLGFINSFIHIIMYAYYLLSAMGPKVQKYLWWKKY 208
Query: 234 VTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLF 293
+T QI+QFLI +FV+ F N F P T +A + Y +F
Sbjct: 209 ITILQIVQFLI--IFVHTLQIQFQPNCNF----PKSIAALLTFNAGLFTY--------MF 254
Query: 294 ISFYIQSYRKGASKKGETENK 314
+FY+ +Y+K A+ + + K
Sbjct: 255 SAFYVANYKKEAAAQAKLAAK 275
>CE05979 [I] KOG3072 Long chain fatty acid elongase
Length = 288
Score = 60.5 bits (145), Expect = 4e-09
Identities = 61/240 (25%), Positives = 85/240 (35%), Gaps = 17/240 (7%)
Query: 82 FGGQALLRKANAAPLKLNFLFQLHNXXXXXXXXXXXXXMVEQIFPMIWNHGLFWSICSKE 141
FG + +R N P +L + N M + F I N G+ S C
Sbjct: 59 FGTKWFMR--NRQPFQLTIPLNIWNFILAAFSIAGAVKMTPEFFGTIANKGIVASYCKVF 116
Query: 142 AFAPXXXXXXX-XXXXXXXXXXXDTVXXXXXXXXXXXXHTYHHGATALLCYSQLQGKTSI 200
F DT+ H YHH T + +
Sbjct: 117 DFTKGENGYWVWLFMASKLFELVDTIFLVLRKRPLMFLHWYHHILTMIYAWYSHPLTPGF 176
Query: 201 EWVVIALNLGVHVVMYWYYFLSARGIRV--WWKEWVTRFQIIQFLIDLVFVYFATYTFYA 258
I LN VH MY YYFL + IRV + + +T QI+QF+I + Y +
Sbjct: 177 NRYGIYLNFVVHAFMYSYYFLRSMKIRVPGFIAQAITSLQIVQFIISCAVLAHLGYLMHF 236
Query: 259 NKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSY--RKGASK-KGETENKN 315
D P S + T+YL LF++F++QSY R G K K + KN
Sbjct: 237 TNANCDFEP---------SVFKLAVFMDTTYLALFVNFFLQSYVLRGGKDKYKAVPKKKN 287
>7294765 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 442
Score = 59.7 bits (143), Expect = 6e-09
Identities = 43/135 (31%), Positives = 65/135 (47%), Gaps = 20/135 (14%)
Query: 179 HTYHHGATALLCYSQLQGK-TSIEWVVIALNLGVHVVMYWYYFLSARGIRV----WWKEW 233
H YHH + C+ ++ T +V +N VH++MY YY LS G RV WWK +
Sbjct: 320 HVYHHSTMFVFCWILIKWMPTGSTYVPAMINSFVHIIMYGYYALSVLGPRVQRFLWWKRY 379
Query: 234 VTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLF 293
+T Q++QF I +F F+A++ + +G YGT + L +L +F
Sbjct: 380 LTGLQLVQFTI--IF-------FWASQ-----MLVRGCEYGTWITLSMAIYSL-PFLFMF 424
Query: 294 ISFYIQSYRKGASKK 308
FY+Q Y A K
Sbjct: 425 GKFYMQKYTVSAVGK 439
>7299267 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 261
Score = 58.5 bits (140), Expect = 1e-08
Identities = 35/129 (27%), Positives = 64/129 (49%), Gaps = 20/129 (15%)
Query: 179 HTYHHGATALL--CYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSA----RGIRVWWKE 232
H +HH + Y G + +I N+ VH +MY YY+ S+ G +WWK+
Sbjct: 135 HVFHHVYMVYIGFLYMYYYGYGGHGFFLITFNVVVHTMMYTYYYQSSLNRNSGGDLWWKK 194
Query: 233 WVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVL 292
++T Q++QF+I +++ Y + D C + +A +G LI +++L
Sbjct: 195 YITVVQLVQFVI------IFSHSVYILRQTD--------CQTSRLSATWGSLISVVFIIL 240
Query: 293 FISFYIQSY 301
F +FY+++Y
Sbjct: 241 FSNFYVRTY 249
>7300878 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 295
Score = 57.0 bits (136), Expect = 4e-08
Identities = 40/134 (29%), Positives = 60/134 (43%), Gaps = 28/134 (20%)
Query: 179 HTYHHGATALLCYSQLQ-----GKTSIEWVVIALNLGVHVVMYWYYFLSARGIR----VW 229
H YHH ++ + + T I W+ N VH++MY YYFLSA G + +W
Sbjct: 144 HVYHHTVMPMISWGTSKYYPGGHGTFIGWI----NSFVHIIMYSYYFLSAFGPQMQKYLW 199
Query: 230 WKEWVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSY 289
WK+++T Q+IQF + YT D P C+ +A + +
Sbjct: 200 WKKYITNLQMIQFCCAFIHQTQLLYT-------DCGYPRWSVCFTLPNAVFFYF------ 246
Query: 290 LVLFISFYIQSYRK 303
LF FY +SY+K
Sbjct: 247 --LFNDFYQKSYKK 258
>CE10284 [I] KOG3072 Long chain fatty acid elongase
Length = 286
Score = 56.6 bits (135), Expect = 5e-08
Identities = 43/150 (28%), Positives = 64/150 (42%), Gaps = 16/150 (10%)
Query: 164 DTVXXXXXXXXXXXXHTYHHGAT---ALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYF 220
DTV H YHH T AL+CY + + WVV +N +H MY YY
Sbjct: 132 DTVFIVLRKRPLIFMHWYHHALTGYYALVCYHE--DAVHMVWVVW-MNYIIHAFMYGYYL 188
Query: 221 LSARGIRV--WWKEWVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESA 278
L + + + + +T Q++QF + + +Y Y +G Y
Sbjct: 189 LKSLKVPIPPSVAQAITTSQMVQFAVAIFAQVHVSYKHYVEGV-------EGLAYSFRGT 241
Query: 279 AAYGYLILTSYLVLFISFYIQSYRKGASKK 308
A G+ +LT+Y L+I FY + Y K KK
Sbjct: 242 AI-GFFMLTTYFYLWIQFYKEHYLKNGGKK 270
>7299266 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 262
Score = 56.6 bits (135), Expect = 5e-08
Identities = 37/129 (28%), Positives = 68/129 (52%), Gaps = 20/129 (15%)
Query: 179 HTYHHGATALLCYSQLQ--GKTSIEWVVIALNLGVHVVMYWYYFLSARGIRV----WWKE 232
H +HH + ++ G +++ N+ VH+VMY YY+ S++ V WWK+
Sbjct: 135 HVFHHVFMVFTSHMLIRFYGFGGHVFLICMFNVLVHIVMYGYYYASSQSQNVQESLWWKK 194
Query: 233 WVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVL 292
++T Q++QFL L+F++ YT++ + ++G Y SA+A+ +L +
Sbjct: 195 YLTLGQLVQFL--LMFLH-CMYTYFQ----PNCSASRGVIYVISSASAFMFL-------M 240
Query: 293 FISFYIQSY 301
F FYI++Y
Sbjct: 241 FTKFYIKTY 249
>7299264 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 265
Score = 56.6 bits (135), Expect = 5e-08
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 19/135 (14%)
Query: 179 HTYHHGATALLCYSQL--QGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRVW---WKEW 233
H +HH + Y + G + + LN+ VHV+MY YY+LS+ V WK++
Sbjct: 138 HVFHHLVMSFGGYLHITFNGYGGTLFPLCLLNVAVHVIMYAYYYLSSVSKDVQTSRWKKY 197
Query: 234 VTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLF 293
+T Q++QF++ L AN + + P+ C + + G I T+++++F
Sbjct: 198 ITIVQLVQFILVL-----------ANFSYTLMQPD---CNASRTVIYTGMFISTTFILMF 243
Query: 294 ISFYIQSYRKGASKK 308
+FYI +Y SK+
Sbjct: 244 ANFYIHNYILNGSKQ 258
>CE19785 [I] KOG3072 Long chain fatty acid elongase
Length = 274
Score = 56.2 bits (134), Expect = 7e-08
Identities = 59/231 (25%), Positives = 90/231 (38%), Gaps = 32/231 (13%)
Query: 84 GQALLRKANAAPLKLNFLFQLHNXXXXXXXXXXXXXMVEQIFPMIWNHGLFWSICSKEAF 143
GQ L+ A+ P L L N ++ ++F + G S C E +
Sbjct: 50 GQKLM--AHRKPFDLQNTLALWNFGFSLFSGIAAYKLIPELFGVFMKDGFVASYCQNENY 107
Query: 144 APXXXXXXXXXXXXXXXX--XXDTVXXXXXXXXXXXXHTYHHGAT---ALLCYSQLQGKT 198
DT+ H YHH T A++ YS+ Q
Sbjct: 108 YTDASTGFWGWAFVMSKAPELGDTMFLVLRKKPVIFMHWYHHALTFVYAVVTYSEHQAWA 167
Query: 199 SIEWVVIALNLGVHVVMYWYYFLSARGIRV--WWKEWVTRFQIIQFLID------LVFVY 250
W +ALNL VH VMY+Y+ + A I+ +++T QI+QF+I LVF+
Sbjct: 168 --RWS-LALNLAVHTVMYFYFAVRALNIQTPRPVAKFITTIQIVQFVISCYIFGHLVFIK 224
Query: 251 FATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSY 301
A D +P C + + + G L+ SYL LF F+ ++Y
Sbjct: 225 SA-----------DSVPG---CAVSWNVLSIGGLMYISYLFLFAKFFYKAY 261
>7302565 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 221
Score = 54.7 bits (130), Expect = 2e-07
Identities = 48/142 (33%), Positives = 67/142 (46%), Gaps = 31/142 (21%)
Query: 179 HTYHH-----GATALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSAR--GIR--VW 229
H YHH G+ AL Y G + V LN VH VMY+YYFLS+ G+R +W
Sbjct: 93 HIYHHVFMSFGSYALTRYYGTGGHVN---AVGLLNSLVHTVMYFYYFLSSEYPGVRANIW 149
Query: 230 WKEWVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTS- 288
WK+++T Q+ QF + L +Y Y ++F PN G G YL +
Sbjct: 150 WKKYITLTQLCQFFMLL------SYAIYV-RFFS---PNCGVPRGLL------YLNMVQG 193
Query: 289 --YLVLFISFYIQSYRKGASKK 308
++ LF FYI +Y + K
Sbjct: 194 VVFIYLFGKFYIDNYLRPPKAK 215
>Hs18561450 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 128
Score = 53.5 bits (127), Expect = 4e-07
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 24/119 (20%)
Query: 207 LNLGVHVVMYWYYFLSARGIR----VWWKEWVTRFQIIQFLIDLVFVYFATYTFYAN-KY 261
LN VHVVMY YY LSA G +WWK+++T Q++QF+I V ++ + + F + KY
Sbjct: 23 LNTAVHVVMYSYYGLSALGPAYQKYLWWKKYLTSLQLVQFVI--VAIHISQFFFMEDCKY 80
Query: 262 FDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSYRKG-----ASKKGETENKN 315
+ C +Y ++ +L+LF+ F+ ++Y KG K G +NK+
Sbjct: 81 QFPVF----ACI----IMSYSFM----FLLLFLHFWYRAYTKGQRLPKTVKNGTCKNKD 127
>Hs12232379 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 314
Score = 53.5 bits (127), Expect = 4e-07
Identities = 44/152 (28%), Positives = 65/152 (41%), Gaps = 32/152 (21%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVV-------IALNLGVHVVMYWYYFLSARGIRV--- 228
H YHH L + I+WV LN +HV+MY YY L+A G +
Sbjct: 158 HVYHHCTMFTLWW------IGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPWIQKY 211
Query: 229 -WWKEWVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILT 287
WWK ++T Q+IQF + + + YT D P A Y I
Sbjct: 212 LWWKRYLTMLQLIQFHVTIGHTALSLYT-------DCPFPK------WMHWALIAYAI-- 256
Query: 288 SYLVLFISFYIQSYRKGASKKGETENKNAAAA 319
S++ LF++FYI++Y++ K N +A
Sbjct: 257 SFIFLFLNFYIRTYKEPKKPKAGKTAMNGISA 288
>Hs8923312 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 296
Score = 53.1 bits (126), Expect = 6e-07
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 31/144 (21%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIA-------LNLGVHVVMYWYYFLS---ARGIRV 228
H YHH + + + L W+ LN VH++MY YY LS + +
Sbjct: 146 HVYHHASMFNIWWCVLN------WIPCGQSFFGPTLNSFVHILMYSYYGLSVFPSMHKYL 199
Query: 229 WWKEWVTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTS 288
WWK+++T+ Q++QF++ + T+T A ++ G +G + + +
Sbjct: 200 WWKKYLTQAQLVQFVLTI------THTMSA------VVKPCGFPFG---CLIFQSSYMLT 244
Query: 289 YLVLFISFYIQSYRKGASKKGETE 312
++LF++FY+Q+YRK KK E
Sbjct: 245 LVILFLNFYVQTYRKKPMKKDMQE 268
>7296847 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 245
Score = 52.0 bits (123), Expect = 1e-06
Identities = 39/145 (26%), Positives = 61/145 (41%), Gaps = 20/145 (13%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIAL-NLGVHVVMYWYYFLSARGIR----VWWKEW 233
H HHG + L+ AL N VH+VMY+YY ++A G + +WWK++
Sbjct: 37 HVIHHGCMPFSVWMGLKFAPGGHSTFFALLNSFVHIVMYFYYMIAAMGPKYQKYIWWKKY 96
Query: 234 VTRFQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLF 293
+T FQ++QF+ A +T F + C + + L +L LF
Sbjct: 97 LTTFQMVQFV--------AIFTHQFQLLFRE-------CDYPKGFMVWIGLHGVMFLFLF 141
Query: 294 ISFYIQSYRKGASKKGETENKNAAA 318
FY Y A ++ + N A
Sbjct: 142 SDFYKAKYLNAARRRRQAVKANGYA 166
>Hs13129088 [I] KOG3072 Long chain fatty acid elongase
Length = 265
Score = 51.6 bits (122), Expect = 2e-06
Identities = 44/178 (24%), Positives = 66/178 (36%), Gaps = 14/178 (7%)
Query: 127 MIWNHGLFWSICSKEAF-APXXXXXXXXXXXXXXXXXXDTVXXXXXXXXXXXXHTYHHGA 185
++ GL S+C + + P DT+ H YHH
Sbjct: 88 ILMTKGLKQSVCDQGFYNGPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHIT 147
Query: 186 TALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRVWWK--EWVTRFQIIQFL 243
L + + + + +N GVH VMY YY L A G RV K ++T QI Q L
Sbjct: 148 VLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQML 207
Query: 244 IDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSY 301
+ V Y ++ C+ + L+ SYLVLF F+ ++Y
Sbjct: 208 MGCVVNYLVFCWMQHDQ-----------CHSHFQNIFWSSLMYLSYLVLFCHFFFEAY 254
>CE00112 [I] KOG3072 Long chain fatty acid elongase
Length = 291
Score = 51.2 bits (121), Expect = 2e-06
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 15/137 (10%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIRV--WWKEWVTR 236
H YHH A + T+ I +N H +MY YY +SA G R+ W VT
Sbjct: 162 HYYHHAAVLIYTVHSGAEHTAAGRFYILMNYFAHSLMYTYYTVSAMGYRLPKWVSMTVTT 221
Query: 237 FQIIQFL--IDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFI 294
Q Q L + + ++ + T Y K C + + ++I ++ +LFI
Sbjct: 222 VQTTQMLAGVGITWMVYKVKTEY-----------KLPCQQSVANLYLAFVIYVTFAILFI 270
Query: 295 SFYIQSYRKGASKKGET 311
F++++Y +SKK ++
Sbjct: 271 QFFVKAYIIKSSKKSKS 287
>Hs13489093 [I] KOG3071 Fatty acyl-CoA elongase/Polyunsaturated fatty acid
specific elongation enzyme
Length = 279
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/103 (33%), Positives = 54/103 (51%), Gaps = 19/103 (18%)
Query: 207 LNLGVHVVMYWYYFLSARG----IRVWWKEWVTRFQIIQFLIDLVFVYFATYTFYAN-KY 261
+N VHV+MY YY LSA G +WWK+ +T Q+IQF+ LV ++ + Y F ++ Y
Sbjct: 170 INSSVHVIMYLYYGLSAFGPVAQPYLWWKKHMTAIQLIQFV--LVSLHISQYYFMSSCNY 227
Query: 262 FDDILPNKGTCYGTESAAAYGYLILTSYLVLFISFYIQSYRKG 304
++ + YG T + +LF +F+ SY KG
Sbjct: 228 QYPVIIHLIWMYG------------TIFFMLFSNFWYHSYTKG 258
>Hs17454617 [I] KOG3072 Long chain fatty acid elongase
Length = 270
Score = 49.7 bits (117), Expect = 6e-06
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 13/125 (10%)
Query: 179 HTYHHGATALLCYSQLQGKTSIEWVVIALNLGVHVVMYWYYFLSARGIR--VWWKEWVTR 236
H YHH + + K + +N GVH +MY YY L A ++ +T
Sbjct: 145 HWYHHSTVLVYTSFGYKNKVPAGGWFVTMNFGVHAIMYTYYTLKAANVKPPKMLPMLITS 204
Query: 237 FQIIQFLIDLVFVYFATYTFYANKYFDDILPNKGTCYGTESAAAYGYLILTSYLVLFISF 296
QI+Q + + V TY + ++ C+ T + +++ +Y +LF F
Sbjct: 205 LQILQMFVGAI-VSILTYIWRQDQ----------GCHTTMEHLFWSFILYMTYFILFAHF 253
Query: 297 YIQSY 301
+ Q+Y
Sbjct: 254 FCQTY 258
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.140 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,301,481
Number of Sequences: 60738
Number of extensions: 579007
Number of successful extensions: 1503
Number of sequences better than 1.0e-05: 28
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1454
Number of HSP's gapped (non-prelim): 29
length of query: 342
length of database: 30,389,216
effective HSP length: 107
effective length of query: 235
effective length of database: 23,890,250
effective search space: 5614208750
effective search space used: 5614208750
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)