ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII1991 good F KOG1907 Nucleotide transport and metabolism Phosphoribosylformylglycinamidine synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII1991 709756 713802 1349
(1349 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR061c [F] KOG1907 Phosphoribosylformylglycinamidine synthase 2031 0.0
SPAC6F12.10c [F] KOG1907 Phosphoribosylformylglycinamidine synthase 1305 0.0
At1g74260 [F] KOG1907 Phosphoribosylformylglycinamidine synthase 694 0.0
7297060 [F] KOG1907 Phosphoribosylformylglycinamidine synthase 579 e-164
CE17651 [F] KOG1907 Phosphoribosylformylglycinamidine synthase 537 e-152
>YGR061c [F] KOG1907 Phosphoribosylformylglycinamidine synthase
Length = 1358
Score = 2031 bits (5263), Expect = 0.0
Identities = 994/1361 (73%), Positives = 1140/1361 (83%), Gaps = 15/1361 (1%)
Query: 1 MSVSILPGPQALSQFRVENLVKALETHCNSTGFIDEIRSCYVHYID-LKTELSKEDEDLV 59
M+ ILPGP+ALSQFRV+NL+K + ++ NST I+E+RSCY+HY++ + LS++D L+
Sbjct: 1 MTDYILPGPKALSQFRVDNLIKDINSYTNSTSVINELRSCYIHYVNGIAQNLSEQDTKLL 60
Query: 60 SVXXXXXXXXXXXXXXNQLLVQSLEQNSDANL-----GNDTYLIRVTPRRGTISPWSSKA 114
V N L + L NL G DTYLIRV PR GTISPWSSKA
Sbjct: 61 EVLLTYDSALDIA---NDPLARQLNDAVANNLPSSALGEDTYLIRVVPRSGTISPWSSKA 117
Query: 115 TNIAHVCNLEDKVNRIERGVALLIKCNPGFPILDRLNDVSLKSVYDRMTQELFLDQPPHA 174
TNIAHVC L+DKV RIERG+ALLIK PGFP+L+ LND+SLK VYDRMTQ+L+L +PP+
Sbjct: 118 TNIAHVCGLQDKVQRIERGLALLIKTVPGFPLLENLNDISLKCVYDRMTQQLYLTEPPNT 177
Query: 175 TELFNHDAPKPLVHVPLVSSHTG-SPADILAKANVELGLALDAGEIEYLIRAFVETMNRD 233
+F H+ PKPLVHVPL T SP DIL+KAN ELGLALD+GE+EYLI AFVETM RD
Sbjct: 178 MSIFTHEEPKPLVHVPLTPKDTKQSPKDILSKANTELGLALDSGEMEYLIHAFVETMKRD 237
Query: 234 PTDVELFMFAQVNSEHCRHKIFNADWTIDGLQKDLSLFKMIRNTHQITPDFTLSAYSDNA 293
PTDVELFMFAQVNSEHCRHKIFNADWTIDG+++ +LF+MIRNTH++ P++T+SAYSDNA
Sbjct: 238 PTDVELFMFAQVNSEHCRHKIFNADWTIDGIKQQFTLFQMIRNTHKLNPEYTISAYSDNA 297
Query: 294 AVLDTENDSYYYAPDFKTKKWTATKERVPMLIKVETHNHPTAVSPFPGASTGSGGEIRDE 353
AVLD+END++++AP+ TK+WT+TKER+P+LIKVETHNHPTAVSPFPGA+TGSGGEIRDE
Sbjct: 298 AVLDSENDAFFFAPNSTTKEWTSTKERIPLLIKVETHNHPTAVSPFPGAATGSGGEIRDE 357
Query: 354 GATGRGSKSKCGLSGFSVSDLLIPGKVQPWELNVGKPNHIASALDIMIEAPLGSAAFNNE 413
GATGRGSK+KCGLSGFSVSDLLIPG QPWELN+GKP HIASALDIMIEAPLGSAAFNNE
Sbjct: 358 GATGRGSKTKCGLSGFSVSDLLIPGNEQPWELNIGKPYHIASALDIMIEAPLGSAAFNNE 417
Query: 414 FGRPCINGYFRTLTTNVINSDGKEEIRGFHKPIMIAGGFGAVRPQFALKNKPITAGSNLI 473
FGRPCINGYFRTLTT V+N GKEEIRGFHKPIMIAGGFG VRPQFALKN PIT GS LI
Sbjct: 418 FGRPCINGYFRTLTTKVLNHQGKEEIRGFHKPIMIAGGFGTVRPQFALKNTPITPGSCLI 477
Query: 474 VXXXXXXXXXXXXXXXXXXXXXXXXXDLDFASVQRGNPEMERRCQQVIDACVSLNESNPI 533
V DLDFASVQRGNPEMERRCQQVIDACV+L +NPI
Sbjct: 478 VLGGQSMLIGLGGGAASSVASGEGSADLDFASVQRGNPEMERRCQQVIDACVALGNNNPI 537
Query: 534 QSIHDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSQ 593
QSIHDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVS
Sbjct: 538 QSIHDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSP 597
Query: 594 QDLATFEEICKRERAPFAVVGHATAEQKLIVEDPLLKSTPIDLEMSILFGKPPKMARTAI 653
QDL+ FEEICKRERAPFAVVGHATAEQKLIVEDPLLK+TPIDLEM ILFGKPPKM+R I
Sbjct: 598 QDLSIFEEICKRERAPFAVVGHATAEQKLIVEDPLLKTTPIDLEMPILFGKPPKMSRETI 657
Query: 654 TEPLQLPQPDLSVIPSMEDAIDRVLHLPSVGSKSFLITIGDRTVTGLIDRDQFVGPWQVP 713
TE L LP+ +LS IPS++DAI RVL+LPSVGSKSFLITIGDR+VTGLIDRDQFVGPWQVP
Sbjct: 658 TEALNLPEANLSEIPSLQDAIQRVLNLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVP 717
Query: 714 VADVGVTATALGDAILSTGEAMAMGERPTTXXXXXXXXXXXXXXXXXXNVFAADIKSLQH 773
VADVGVT T+LG+ I+STGEAMAMGE+P N+FAAD+KSL H
Sbjct: 718 VADVGVTGTSLGETIISTGEAMAMGEKPVNALISASASAKLSVAESLLNIFAADVKSLNH 777
Query: 774 VKLSANWMSPASHKGEGAKLYEAVQAIGMDLCPELGVSIPVGKDSMSMKMKWDDKEVTAP 833
+KLSANWMSPASH+GEG+KLYEAVQA+G+DLCP LGV+IPVGKDSMSMKMKWDDKEVTAP
Sbjct: 778 IKLSANWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAP 837
Query: 834 LSVTITAFAPVNNTSKTWTPVLNSEAGDTILVLVDLAALQEKRSLGSSAFLQVYNQIGDT 893
LS+ ITAFAPV NTSKTWTP+LN D++LVLVDL+A QE +SLG+SA LQVYNQ+G+
Sbjct: 838 LSLNITAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNK 897
Query: 894 APTVHDNKVLRGFLESLLDLH--KTDLVLSYHDRSDGGLLVTLLEMAFASRCGLDVVIDT 951
+PTV+DN +L+GFLESL+ LH K D+VL+YHDRSDGGLL+TLLEMAFASRCGL++ ID
Sbjct: 898 SPTVYDNAILKGFLESLIQLHQQKEDIVLAYHDRSDGGLLITLLEMAFASRCGLEINIDG 957
Query: 952 VKDGNPFVPLFNEELGAVFQIKESSLSEFQSVLNAHGVSNEYISVVAKPNFAAHQI-TIS 1010
+ LFNEELGAVFQI +LS+F+ +LN +GV+ EYIS+V KP+F + +I I+
Sbjct: 958 GDLESQLTNLFNEELGAVFQISAKNLSKFEKILNENGVAKEYISIVGKPSFQSQEIKIIN 1017
Query: 1011 DKAGSAIFQGTRGKLQQAWSSTSYEMQKLRDNPKTTVQEFSAINDDKDPGLHYALTYNPT 1070
I+ +R +L+Q WS TSYEMQKLRDNPKT +EF++I DD+DPGL YALTYNP
Sbjct: 1018 STTNDVIYANSRSELEQTWSKTSYEMQKLRDNPKTAEEEFASITDDRDPGLQYALTYNPA 1077
Query: 1071 DDLQIGAQLSAVRPKVAILREQGVNGQMEMAWCFQQAGFDPIDVTMTDLIGGKFNLNEFT 1130
DD++IG +LS+ RPKVAILREQGVNGQMEMAWCFQQAGF+ +DVTMTDL+ G+F+L++F
Sbjct: 1078 DDMKIGLELSSQRPKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFI 1137
Query: 1131 GMAACGGFSYGDVLGAGAGWAKSVLYHEGVRKQFVNFFQEREDTFAFGACNGCQFLSRLK 1190
G+AACGGFSYGDVLGAGAGWAKSVLYHEGVR QF FF ER+DTFAFGACNGCQFLSRLK
Sbjct: 1138 GLAACGGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLK 1197
Query: 1191 SIIPGCENWPSFERNLSEQYEARVCMVEIVQD-DGAEAQSVFFNGMVGSKLPIAVAHGEG 1249
IIPGCENWPSFERN+SEQYEARVCMV+I Q+ D + +SVF NGM GSKLPIAVAHGEG
Sbjct: 1198 DIIPGCENWPSFERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEG 1257
Query: 1250 KATFT-DEDQLKRFEEQGLTGVRYVDNYGNVTEKFPFNPNGSPNGISGIKSPNGRVLAMM 1308
KATF+ +QL++FE+ GL +RYVDNYGNVTE+FPFNPNGS NGI+GIKSPNGRVLAMM
Sbjct: 1258 KATFSKSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMM 1317
Query: 1309 PHPERVCRLESNSWYPDGKYEEWEGYGPWIRLFRSARKWVG 1349
PHPERVCRLE+NSWYP+GKYEEW GYGPWIRLFRSAR+WVG
Sbjct: 1318 PHPERVCRLEANSWYPEGKYEEWGGYGPWIRLFRSARRWVG 1358
>SPAC6F12.10c [F] KOG1907 Phosphoribosylformylglycinamidine synthase
Length = 1323
Score = 1305 bits (3377), Expect = 0.0
Identities = 685/1274 (53%), Positives = 866/1274 (67%), Gaps = 36/1274 (2%)
Query: 95 TYLIRVTPRRGTISPWSSKATNIAHVCNLEDKVNRIERGVALLIKCNPGFPILDRLNDVS 154
T ++ V PR GTISPWSSKATNIA+VC +D + RIERG+A + I + + +
Sbjct: 67 TTMVYVFPRPGTISPWSSKATNIANVCGYKDVI-RIERGIAYSVVFKDD--ISEEMLKSA 123
Query: 155 LKSVYDRMTQELFLDQPPHATELFNHDAPKPLVHVPLVSSHTG---SPADILAKANVELG 211
L +YDRMT+ L + P E+F+ P PLV + L G + + L AN + G
Sbjct: 124 LNHLYDRMTEALRF-KLPEEDEVFDKHEPAPLVRIELNCGQGGDKQAATERLNHANKKFG 182
Query: 212 LALDAGEIEYLIRAFVET---MNRDPTDVELFMFAQVNSEHCRHKIFNADWTIDGLQKDL 268
LAL EI+YL+ + +R+PTDVELFMF QVNSEHCRHKIFNADWTIDG +KD
Sbjct: 183 LALAPDEIDYLVECYTSEPSLKSREPTDVELFMFGQVNSEHCRHKIFNADWTIDGEKKDY 242
Query: 269 SLFKMIRNTHQITPDFTLSAYSDNAAVLDTENDSYYYAPDFKTKKWTATKERVPMLIKVE 328
SLFKMIRNTH P +T+SAYSDNAAV + N +AP W+ E V L KVE
Sbjct: 243 SLFKMIRNTHLKNPQYTISAYSDNAAVFEG-NSGTLFAP--VNGIWSMKDEPVEFLGKVE 299
Query: 329 THNHPTAVSPFPGASTGSGGEIRDEGATGRGSKSKCGLSGFSVSDLLIPGKVQPWELNVG 388
THNHPTAVSPFPGA+TGSGGEIRDEGA G+GS SK GL+G+SVSDL IPG QPWEL+VG
Sbjct: 300 THNHPTAVSPFPGAATGSGGEIRDEGAVGQGSLSKAGLAGYSVSDLNIPGYKQPWELDVG 359
Query: 389 KPNHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTNVINSDGKEEIRGFHKPIMI 448
KP HIA++LDIM+EAP+GS+AFNNEFGRPCINGYFRT V DG EIRG+HKPIM
Sbjct: 360 KPYHIATSLDIMLEAPIGSSAFNNEFGRPCINGYFRTFCMEVPRGDGTLEIRGYHKPIMA 419
Query: 449 AGGFGAVRPQFALKNKPITAGSNLIVXXXXXXXXXXXXXXXXXXXXXXXXXDLDFASVQR 508
AGG G +R Q A K K I GS +IV +LDFASVQR
Sbjct: 420 AGGIGRIRKQHAFK-KSIAPGSPIIVLGGPALLVGLGGGAASSMNAGEGSEELDFASVQR 478
Query: 509 GNPEMERRCQQVIDACVSLNESNPIQSIHDVGAGGLSNALPELVHDNDLGAKFDIRKVLS 568
GNPEM+RR Q VIDAC +++E N IQSIHDVGAGG+SNALPELVHD LGA+F++R +
Sbjct: 479 GNPEMQRRAQMVIDACTTMDE-NIIQSIHDVGAGGVSNALPELVHDAGLGARFELRDIPC 537
Query: 569 LEPGMSPMEIWCNESQERYVLGVSQQDLATFEEICKRERAPFAVVGHATAEQKLIVEDPL 628
+EP MSPM+IWC ESQERYVL V +DL TF+ IC+RER P+ VVG++T EQ+LI+ D L
Sbjct: 538 IEPSMSPMQIWCCESQERYVLSVKSEDLDTFKSICERERCPYGVVGYSTVEQRLILTDRL 597
Query: 629 LKSTPIDLEMSILFGKPPKMARTAITEPLQLPQPDLS----VIPSME---DAIDRVLHLP 681
+TPIDL M +LFGKPPKM+R A T+ + L + D S + PS + DA++RVL +P
Sbjct: 598 YNTTPIDLPMEVLFGKPPKMSRVAETQTIPLSKFDSSLKSYLAPSSDPILDAVERVLRMP 657
Query: 682 SVGSKSFLITIGDRTVTGLIDRDQFVGPWQVPVADVGVTATALGDAILSTGEAMAMGERP 741
+V SKSFLITIGDR+VTGLI RDQ VGPWQVPVADVGVT T+ G I +TGEA+AMGE+P
Sbjct: 658 AVASKSFLITIGDRSVTGLIARDQMVGPWQVPVADVGVTVTSYGKGI-NTGEALAMGEKP 716
Query: 742 TTXXXXXXXXXXXXXXXXXXNVFAADIKSLQHVKLSANWMSPASHKGEGAKLYEAVQAIG 801
+ N+ AA I +L ++LSANWM+ SH GEGAKLYEAVQAIG
Sbjct: 717 ISALVSAAASARMAVAECIMNLVAASIPALDRIRLSANWMAAPSHPGEGAKLYEAVQAIG 776
Query: 802 MDLCPELGVSIPVGKDSMSMKMKWD----DKEVTAPLSVTITAFAPVNNTSKTWTPVLN- 856
++LCP LG+SIPVGKDSMSM MKW+ +K VTAPLS+ IT F+PV++ WTP L
Sbjct: 777 LELCPSLGISIPVGKDSMSMSMKWNEDGREKSVTAPLSLIITGFSPVDDLYSIWTPQLRK 836
Query: 857 -SEAGDTILVLVDLAALQEKRSLGSSAFLQVYNQIGDTAPTVHDNKVLRGFLESLLDLHK 915
+ G T L+ +DLA K+ LG S Q Y Q+GD P + + + F+ + LHK
Sbjct: 837 VEDIGSTSLIFIDLA--NGKQRLGGSILAQSYKQLGDEVPDLDNLDTFKNFINVITQLHK 894
Query: 916 TDLVLSYHDRSDGGLLVTLLEMAFASRCGLDVVIDTVKDGNPFVPLFNEELGAVFQIKES 975
T+ + +YHD+SDGGL VTL EMAFA G++ +D++ N LFNEELGAV Q+ +
Sbjct: 895 TNYIQAYHDKSDGGLFVTLSEMAFAGHVGIECELDSLSSDN-IAALFNEELGAVIQVCDR 953
Query: 976 SLSEFQSVLNAHGVSNEYISVVAKPNFAAHQITISDKAGSAIFQGTRGKLQQAWSSTSYE 1035
+++ + A+G+S + + K Q ++G IF+ TR KL W TSY+
Sbjct: 954 DIAKVLELFAANGLST-CVHRIGKVLSGQAQTISFSRSGKIIFKSTRSKLHGIWHETSYK 1012
Query: 1036 MQKLRDNPKTTVQEFSAINDDKDPGLHYALTYNPTDDLQIGAQLSAVRPKVAILREQGVN 1095
MQ++RDNP+ QE I D+ DPGL Y LT++P + L++ RPKVAILREQGVN
Sbjct: 1013 MQEIRDNPECARQEMENIADNNDPGLGYHLTFDPNVSVTADLALTS-RPKVAILREQGVN 1071
Query: 1096 GQMEMAWCFQQAGFDPIDVTMTDLIGGKFNLNEFTGMAACGGFSYGDVLGAGAGWAKSVL 1155
G +EMA+ F +GF +DV MTD++ G+ +L++F G+AACGGFSYGDVLG+G GWA S+L
Sbjct: 1072 GYLEMAYAFYASGFTAVDVHMTDILSGRVHLDDFVGIAACGGFSYGDVLGSGNGWATSIL 1131
Query: 1156 YHEGVRKQFVNFFQEREDTFAFGACNGCQFLSRLKSIIPGCENWPSFERNLSEQYEARVC 1215
HE R +F FF ER+DTF G CNGCQ SRLKS+IPG ++WP F N S QYE R
Sbjct: 1132 LHEDARNEFYRFFNERKDTFGLGICNGCQLFSRLKSLIPGAKSWPMFTFNESAQYEGRAV 1191
Query: 1216 MVEIVQDDGAEAQSVFFNGMVGSKLPIAVAHGEGKATFTDEDQLKRFEEQGLTGVRYVDN 1275
M++I D+ + ++S+F M GS LP+ VAHGEG+A F E ++F+++GL + YV+N
Sbjct: 1192 MLKI--DETSGSKSIFTESMAGSSLPVVVAHGEGRAVFDSESDYEQFKKEGLDLIYYVNN 1249
Query: 1276 YGNVTEKFPFNPNGSPNGISGIKSPNGRVLAMMPHPERVCRLESNSWYPDGKYEEWEGYG 1335
Y T ++PFNPNGS + I+G++SP GR LAMMPHPERV +NS+YP K EW +G
Sbjct: 1250 YNERTSRYPFNPNGSRDAIAGVRSPCGRFLAMMPHPERVVLKVANSYYPHSKASEWGVHG 1309
Query: 1336 PWIRLFRSARKWVG 1349
PWIRLF+SARKWVG
Sbjct: 1310 PWIRLFQSARKWVG 1323
>At1g74260 [F] KOG1907 Phosphoribosylformylglycinamidine synthase
Length = 1387
Score = 694 bits (1792), Expect = 0.0
Identities = 462/1296 (35%), Positives = 674/1296 (51%), Gaps = 81/1296 (6%)
Query: 90 NLGNDTYL------------IRVTPRRGTISPWSSKATNIAHVCNLEDKVNRIERGVALL 137
NLG D++L + V PR + WS+ A +I C L D+V R+ER L
Sbjct: 133 NLGTDSFLERKKQEGLHAVIVEVGPRLSFTTAWSTNAVSICRACGL-DEVTRLERSRRYL 191
Query: 138 IKCNPGFPILDRLNDVSLKSVYDRMTQELFLDQPPHATELFNHDAPKPLVHVPLVSSHTG 197
+ P+L+ V+DRMT+ ++ + + P+ + +VP++ G
Sbjct: 192 LFSKE--PLLENQIKEFAAMVHDRMTECVYTQK---LVSFETNVVPEEVKYVPVMEK--G 244
Query: 198 SPADILAKANVELGLALDAGEIEYLIRAFVETMNRDPTDVELFMFAQVNSEHCRHKIFNA 257
A L + N E+GLA D +++Y R F E + RDPT+VELF AQ NSEH RH F
Sbjct: 245 RKA--LEEINQEMGLAFDEQDLQYYTRLFREDIKRDPTNVELFDIAQSNSEHSRHWFFAG 302
Query: 258 DWTIDGLQKDLSLFKMIRNTHQITPDFTLSAYSDNAAVLD--TENDSYYYAPDFKTKKWT 315
+ IDG D SL +++++T + + ++ + DN++ + N P
Sbjct: 303 NMVIDGKPMDKSLMQIVKSTWEANRNNSVIGFKDNSSAIRGFLVNQLRPLLPGSVCLLDV 362
Query: 316 ATKERVPMLIKVETHNHPTAVSPFPGASTGSGGEIRDEGATGRGSKSKCGLSGFSVSDLL 375
+ ++ + +L ETHN P AV+P+PGA TG+GG IRD ATGRGS SG+ V +L
Sbjct: 363 SARD-LDILFTAETHNFPCAVAPYPGAETGAGGRIRDTHATGRGSFVVASTSGYCVGNLN 421
Query: 376 IPGKVQPWE-LNVGKPNHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTNVINSD 434
+ G PWE + P+++AS L I+I+A G++ + N+FG P I GY RT + + D
Sbjct: 422 MEGSYAPWEDSSFQYPSNLASPLQILIDASNGASDYGNKFGEPMIQGYTRTFGMRLPSGD 481
Query: 435 GKEEIRGFHKPIMIAGGFGAVRPQFALKNKPITAGSNLIVXXXXXXXXXXXXXXXXXXXX 494
+E + KPIM + G G + K +P G ++
Sbjct: 482 RREWL----KPIMFSAGIGQIDHTHITKGEP-EVGMLVVKIGGPAYRIGMGGGAASSMVS 536
Query: 495 XXXXXDLDFASVQRGNPEMERRCQQVIDACVSLNESNPIQSIHDVGAGGLSNALPELVHD 554
+LDF +VQRG+ EM ++ +V+ AC+ + E NPI SIHD GAGG N + E+++
Sbjct: 537 GQNDAELDFNAVQRGDAEMSQKLYRVVRACIEMGEKNPIISIHDQGAGGNCNVVKEIIYP 596
Query: 555 NDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSQQDLATFEEICKRERAPFAVVG 614
GA+ DIR V+ + MS +EIW E QE+ + V + + ICKRER AV+G
Sbjct: 597 Q--GAEIDIRAVVVGDHTMSVLEIWGAEYQEQDAILVKAESREILQSICKRERLSMAVIG 654
Query: 615 -----------HATAEQKLIVEDPLLKSTPIDLEMSILFGKPPKMARTAITEPLQLPQPD 663
+TA K E +DLE+ + G PK +T + +
Sbjct: 655 TINGGGRCTLIDSTAAAKCSKEGLPPPPPAVDLELEKVLGDMPK--KTFKFNRIAYAREP 712
Query: 664 LSVIP--SMEDAIDRVLHLPSVGSKSFLITIGDRTVTGLIDRDQFVGPWQVPVADVGVTA 721
L + P ++ DA+ RVL LPSV SK FL T DR VTGL+ + Q VGP Q+ +ADV V A
Sbjct: 713 LDIAPGITLMDALKRVLRLPSVSSKRFLTTKVDRCVTGLVAQQQTVGPLQITLADVAVIA 772
Query: 722 TALGDAILSTGEAMAMGERPTTXXXXXXXXXXXXXXXXXXNVFAADIKSLQHVKLSANWM 781
D TG A A+GE+P N+ A + +L VK S NWM
Sbjct: 773 QTFTDL---TGGACAIGEQPIKGLLDPKAMARLAVGEALTNLVWAKVTALSDVKASGNWM 829
Query: 782 SPASHKGEGAKLYEAVQAIGMDLCPELGVSIPVGKDSMSMKMKWDDKEVTAPLSVTITAF 841
A +GEG+ +Y+A A+ + ELG++I GKDS+SM D + V AP ++ I+A+
Sbjct: 830 YAAKLEGEGSAMYDAAIALSEAMI-ELGIAIDGGKDSLSMAAHADGEVVKAPGNLVISAY 888
Query: 842 APVNNTSKTWTPVLNSEAGDTILVLVDLAALQEKRSLGSSAFLQVYNQIGDTAPTVHDNK 901
+ +KT TP L D IL+ VDLA + KR LG SA QV+ QIG+ P + D
Sbjct: 889 VTCPDITKTVTPDLKLGGDDGILLHVDLA--KGKRRLGGSALAQVFGQIGNDCPDLDDVP 946
Query: 902 VLRGFLESLLDLHKTDLVLSYHDRSDGGLLVTLLEMAFASRCGLDVVIDTVKDG-NPFVP 960
L+ + + L +LV + HD SDGGL+VT LEMAFA G++ +D +G + F
Sbjct: 947 YLKNVFDGVQALIAENLVSAGHDISDGGLVVTALEMAFAGNKGIN--LDLASNGISLFET 1004
Query: 961 LFNEELGAVFQIKESSLSEFQSVLNAHGVSNEYI-SVVAKPNFAAHQITISDKAGSAIFQ 1019
LF+EELG V +I +++L L A V+ E I +V P I+ + F
Sbjct: 1005 LFSEELGLVLEISKTNLDAVMEKLRAFDVTAEIIGNVTDSPLIEVKVDGITHLSEKTSF- 1063
Query: 1020 GTRGKLQQAWSSTSYEMQKLRDNPKTTVQEFSAINDDKDPGLHYALTYNPTDDLQIGAQL 1079
L+ W TS++++KL+ E + +P + + T++ +
Sbjct: 1064 -----LRDMWEDTSFQLEKLQRLASCVEMEKEGLKFRHEPNWKLSFIPSSTNNNYMS--- 1115
Query: 1080 SAVRPKVAILREQGVNGQMEMAWCFQQAGFDPIDVTMTDLIGGKFNLNEFTGMAACGGFS 1139
+ PKVA++RE+G NG EM+ F AGF+P DVT++DL+ G L++F G+ GGFS
Sbjct: 1116 QGMIPKVAVIREEGSNGDREMSAAFYAAGFEPWDVTVSDLLAGDITLDQFRGIVFVGGFS 1175
Query: 1140 YGDVLGAGAGWAKSVLYHEGVRKQFVNFFQEREDTFAFGACNGCQFLSRLKSIIPGCE-- 1197
Y DVL + GWA S+ ++E V QF F++ R DTF+ G CNGCQ ++ L +PG +
Sbjct: 1176 YADVLDSAKGWAASIRFNEPVLSQFQEFYK-RPDTFSLGICNGCQLMALL-GWVPGPQVG 1233
Query: 1198 -----NWPSFERNLSEQYEARVCMVEIVQDDGAEAQSVFFNGMVGSKLPIAVAHGEGKAT 1252
+ P F N S ++E R V I ++ S+ GM GS L + AHGEG+A
Sbjct: 1234 GSLDTSQPRFVHNESGRFECRFTSVTI-----KDSPSIMLKGMEGSTLGVWAAHGEGRAY 1288
Query: 1253 FTDEDQLKRFEEQGLTGVRYVDNYGNVTEKFPFNPNGSPNGISGIKSPNGRVLAMMPHPE 1312
F DE L L +RY D+ GNVTE +PFN NGSP GI+ I SP+GR LAMMPHPE
Sbjct: 1289 FPDEGVLDHMLHSDLAPLRYCDDDGNVTEAYPFNLNGSPLGIAAICSPDGRHLAMMPHPE 1348
Query: 1313 RVCRLESNSWYPDGKYEEWEGYGPWIRLFRSARKWV 1348
R + WYP E G PW+++F++AR W+
Sbjct: 1349 RCFLMWQFPWYPTSWDVEKAGPSPWLKMFQNARDWL 1384
>7297060 [F] KOG1907 Phosphoribosylformylglycinamidine synthase
Length = 1354
Score = 579 bits (1492), Expect = e-164
Identities = 415/1300 (31%), Positives = 628/1300 (47%), Gaps = 77/1300 (5%)
Query: 92 GNDTYLIRVTPRRGTISPWSSKATNIAHVCNLEDKVNRIERGVALLIKCNPGFPILDRLN 151
G+ L+ + PR +P+S+ NI + V R+E L+ G +
Sbjct: 82 GSSQLLLEIGPRFNFSTPYSTNCVNIFQNLGYSE-VRRMETSTRYLVTFGEGSKAPEAAR 140
Query: 152 DVSLKSVYDRMTQELFLDQ-PPHATELFNHDAPKPLVH---VPLVSSHTGSPADILAKAN 207
V L DRMTQ L+ ++ P A+ F+ P+ + VP++ + L + N
Sbjct: 141 FVPLLG--DRMTQCLYTEENTPKAS--FDEQLPERQANWHFVPVLEEGRAA----LERIN 192
Query: 208 VELGLALDAGEIEYLIRAFVETMNRDPTDVELFMFAQVNSEHCRHKIFNADWTIDGLQKD 267
ELGLA + +++Y F + + R+PT VELF AQ NSEH RH F IDG+++
Sbjct: 193 QELGLAFNDYDLDYYHDLFAKELGRNPTTVELFDCAQSNSEHSRHWFFRGRMVIDGVEQP 252
Query: 268 LSLFKMIRNTHQITPDFTLSAYSDNAAVLDTENDSYYYAPDFKTKKWTATKERVP--MLI 325
SL +MI +T T +SDN++ + D P + V ++
Sbjct: 253 KSLIRMIMDTQAHTNPNNTIKFSDNSSAM-VGFDHQTIVPSSVVAPGAVRLQSVQSDLIF 311
Query: 326 KVETHNHPTAVSPFPGASTGSGGEIRDEGATGRGSKSKCGLSGFSVSDLLIPGKVQPWE- 384
ETHN PTAV+PF GA+TG+GG +RD GRG G +G+ V L IPG QP+E
Sbjct: 312 TAETHNMPTAVAPFSGATTGTGGRLRDVQGVGRGGVPIAGTAGYCVGALHIPGYKQPYEP 371
Query: 385 LNVGKPNHIASALDIMIEAPLGSAAFNNEFGRPCINGYFRTLTTN-VINSDGKEEIRGFH 443
L+ P A L ++IEA G++ + N+FG P I+G+ + N ++ ++E +
Sbjct: 372 LDFKYPATFAPPLQVLIEASNGASDYGNKFGEPVISGFALSYGLNSAADASQRDE---YV 428
Query: 444 KPIMIAGGFGAVRPQFALKNKPITAGSNLIVXXXXXXXXXXXXXXXXXXXXXXXXXDLDF 503
KPIM +GG G + K P + +LDF
Sbjct: 429 KPIMFSGGLGTMPATMREKLPPARGQLLAKIGGPVYRIGVGGGAASSVEIQGSGDAELDF 488
Query: 504 ASVQRGNPEMERRCQQVIDACVSLNESNPIQSIHDVGAGGLSNALPELVHDNDLGAKFDI 563
+VQRG+ EME + +V+ AC+ L E NPI +IHD GAGG N L ELV GA
Sbjct: 489 NAVQRGDAEMENKLNRVVRACLDLGEQNPILAIHDQGAGGNGNVLKELVEPGFAGAVIFS 548
Query: 564 RKVLSLEPGMSPMEIWCNESQERYVLGVSQQDLATFEEICKRERAPFAVVGHATAEQKL- 622
++ +P ++ +E+W E QE + + E+IC+RER P + VG T + ++
Sbjct: 549 KEFQLGDPTITALELWGAEYQENNAILCNADQRELLEKICRRERCPISFVGVVTGDGRVT 608
Query: 623 IVEDPLLKS-------------TPIDLEMSILFGKPPKMARTAITEPLQLPQPDLSVIPS 669
++E P K +P DLE+ + G PK RT + Q P +LS+
Sbjct: 609 LLEKPAPKDLEQALNASNRSEVSPFDLELKYVLGDMPK--RTYDLKREQTPLKELSLPKG 666
Query: 670 --MEDAIDRVLHLPSVGSKSFLITIGDRTVTGLIDRDQFVGPWQVPVADVGVTATALGDA 727
+++A++RVL L +VGSK FL DR V GLI + Q VGP Q P+AD +T +
Sbjct: 667 LLLDEALERVLSLVAVGSKRFLTNKVDRCVGGLIAQQQCVGPLQAPLADYALTTVS---H 723
Query: 728 ILSTGEAMAMGERPTTXXXXXXXXXXXXXXXXXXNVFAADIKSLQHVKLSANWMSPASHK 787
+G A ++G +P N+ I L VK S NWM A
Sbjct: 724 FSHSGIATSIGTQPLKGLLDPAAMARMCVAEALSNLVFVKISELADVKCSGNWMWAAKLP 783
Query: 788 GEGAKLYEAVQAIGMDLCPELGVSIPVGKDSMSMKMKWDDKEVTAPLSVTITAFAPVNNT 847
GEGA++++A + + + EL ++I GKDS+SM K + + +P ++ I+ +AP +
Sbjct: 784 GEGARMFDACKEL-CQILEELHIAIDGGKDSLSMAAKVGGETIKSPGTLVISTYAPCPDV 842
Query: 848 SKTWTPVLNSEAGDTILVLVDLAALQEKRSLGSSAFLQVYNQIGDTAPTVHDNKVLRGFL 907
TP L + L+ + L+ LG SA Q Y Q G P + + VL
Sbjct: 843 RLKVTPDLKGPGAGSKTSLLWI-NLENSARLGGSALAQAYAQQGKDTPNLTRSDVLGKAF 901
Query: 908 ESLLDLHKTDLVLSYHDRSDGGLLVTLLEMAFASRCGLDVVID-----------TVKDGN 956
L L+ + HD SDGGLLV +LEMA GL V + +V+ N
Sbjct: 902 AVTQSLLGDGLIQAGHDVSDGGLLVCVLEMAIGGLSGLRVDLSEPLAKLKNFDKSVEKLN 961
Query: 957 --PFVPLFNEELGAVFQIKESSLSEFQSVLNAHGVSNEYISVVAKPNFAAHQITISDKAG 1014
LF EE G V ++ ++ L +S GV N Y+ V F +
Sbjct: 962 RPELAVLFAEECGWVVEVLDTDLERVRSTYEKAGVPNYYLGVT--EGFGLDSRVVLKNGK 1019
Query: 1015 SAIFQGTRGKLQQAWSSTSYEMQKLRDNPKTTVQEFSAINDDKDPGLHYALTYNPTDDLQ 1074
S + L + W TSYE++KL+ NP+ E++++ + P Y N +L
Sbjct: 1020 SELLDQPLRVLYKKWERTSYELEKLQANPECAEAEYNSLEYRQAP--QYRGPQNVQAELT 1077
Query: 1075 IGAQLSAVRPKVAILREQGVNGQMEMAWCFQQAGFDPIDVTMTDLIGGKFNLNEFTGMAA 1134
+ + VR VA+LRE+GVN + EM C +A F+ DVTM+DL+ G +++++ G+
Sbjct: 1078 LKRSSAPVR--VAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRGLIF 1135
Query: 1135 CGGFSYGDVLGAGAGWAKSVLYHEGVRKQFVNFFQEREDTFAFGACNGCQ------FLSR 1188
GGFSY D LG+ GWA ++L++ + QF F+ R+D F+ G CNGCQ F+
Sbjct: 1136 PGGFSYADTLGSAKGWAANILHNPRLLPQF-EAFKRRQDVFSLGICNGCQLMTLIGFVGS 1194
Query: 1189 LKSIIPGCENWPSFERNLSEQYEARVCMVEIVQDDGAEAQSVFFNGMVGSKLPIAVAHGE 1248
KS + G + + N S+++E R V+I + +S+ M L VAHGE
Sbjct: 1195 AKSEV-GADPDVALLHNKSQRFECRWATVKIPSN-----RSIMLGSMKDLVLGCWVAHGE 1248
Query: 1249 GKATFTDEDQLKRFEEQGLTGVRYVDNYGNVTEKFPFNPNGSPNGISGIKSPNGRVLAMM 1308
G+ F DE + + + L ++YVD+ G TE +P NPNGSP GI+G+ S +GR LA+M
Sbjct: 1249 GRFAFRDEKLISHLQSEQLVTLQYVDDVGKPTELYPLNPNGSPQGIAGLCSSDGRHLALM 1308
Query: 1309 PHPERVCRLESNSWYPDG-KYEEWEGYGPWIRLFRSARKW 1347
PHPER + + P + + PW +F +A W
Sbjct: 1309 PHPERCSSMYQWPYVPSSFEVSPTQSESPWQIMFNNAYNW 1348
>CE17651 [F] KOG1907 Phosphoribosylformylglycinamidine synthase
Length = 1343
Score = 537 bits (1383), Expect = e-152
Identities = 410/1278 (32%), Positives = 626/1278 (48%), Gaps = 106/1278 (8%)
Query: 127 VNRIERGVALLIKCNPGFPILDRLNDVSLKSVY----DRMTQELFLDQPPHATELFNHDA 182
V RIERG+ L++ +DV + + D+MT+ ++ + E +H
Sbjct: 113 VERIERGIRYLVE-----------DDVDVNEFFEIAADKMTEAIYGNDVKFDDE--SHQI 159
Query: 183 PKPLVHVPLVSSHTGSPADILAKANVELGLALDAGEIEYLIRAFVETMNRDPTDVELFMF 242
K + L S L KAN ELGLALD ++++ FV + ++PTDVELF
Sbjct: 160 EKVFLIDVLESKQN------LIKANEELGLALDQLDLDFYYDFFVNKVKKNPTDVELFDL 213
Query: 243 AQVNSEHCRHKIFNADWTIDGLQKDLSLFKMIRNTHQITPDFTLSAYSDNAAVLDTENDS 302
AQ +SEH RH F + ID ++D SL K IR T + D +L A+ DN++ +
Sbjct: 214 AQSDSEHSRHWFFRGEIWIDDRKRDGSLMKTIRETLDSSNDNSLIAFCDNSSAIRGFESV 273
Query: 303 YYYAPDFKT--KKWTATKERVPMLIKVETHNHPTAVSPFPGASTGSGGEIRDEGATGRGS 360
P+ T A ++ ETHN PTAV PF GA+TG+GG IRD ATGRG+
Sbjct: 274 CRLRPNDPTTVSPMIAIFPPSHLIYSAETHNFPTAVCPFQGATTGTGGRIRDIHATGRGA 333
Query: 361 KSKCGLSGFSVSDLLIPGKVQPWELNVGK-PNHIASALDIMIEAPLGSAAFNNEFGRPCI 419
G G+S +L +PG PWE + P I+ I IEA G++ + N+FG P I
Sbjct: 334 YEIAGTVGYSFGNLNLPGLPLPWEDETFEYPTSISEPAKIAIEASNGASDYGNKFGEPVI 393
Query: 420 NGYFRTLTTNVINSDGKEEIRGFHKPIMIAGGFGAVRPQFALKNKPITAGSNLI-VXXXX 478
+G+ R+ + N + E + KPIM +GG GA+ + ++ +P ++ +
Sbjct: 394 SGFARSFGQRLENGERCE----YLKPIMFSGGIGAI-DKDEVRKEPCAPHQKVVKIGGPV 448
Query: 479 XXXXXXXXXXXXXXXXXXXXXDLDFASVQRGNPEMERRCQQVIDACVSLNESNPIQSIHD 538
LDFA+VQRG+ EM + +V+ AC NP+ +IHD
Sbjct: 449 YRIGVGGGAASSVSVQGNRENQLDFAAVQRGDAEMGGKLHRVVRACAERIGGNPLMAIHD 508
Query: 539 VGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSQQDLAT 598
GAGG N + ELV + K D ++ + +S E+W E QE V L
Sbjct: 509 QGAGGNGNVIKELVEGCGVTVKSDTFQL--GDESISLRELWTAEYQENDAALVDASLLDA 566
Query: 599 FEEICKRERAPFAVVGHATAEQKLIVEDPLLKSTPIDLEMSI-LFGKPPKMARTAITEPL 657
+ I KRE+ +VVG EQ++ + L KS I +++ G+ K + P
Sbjct: 567 LQTISKREKCHVSVVGEVEKEQRVKL---LGKSGEIAVDLDTRQLGEREKKVFKLKSAPR 623
Query: 658 QLPQPDLSVIPSMEDAIDRVLHLPSVGSKSFLITIGDRTVTGLIDRDQFVGPWQVPVADV 717
L + +L ++ A+ RVL LPSV SK +L DR+VTGL+ + Q VGP P+ADV
Sbjct: 624 VLKKLELPENLTVRKALKRVLMLPSVASKRYLTCKVDRSVTGLVAQQQCVGPLHTPLADV 683
Query: 718 GVTATALGDAILSTGEAMAMGERPTTXXXXXXXXXXXXXXXXXXNVFAADIK-------- 769
V A + D + G A+++GE+P N+ A I
Sbjct: 684 AVVALSHFDTV---GGAVSLGEQPIKMLIDAEKGARMCIAETIMNLIWAPITDLKVHFLI 740
Query: 770 -----------SLQHVKLSANWMSPASHKGEGAKLYEAVQAIGMDLCPELGVSIPVGKDS 818
SL+ VK+S NWM A GEGA+L +AV A+ L E+G +I GKDS
Sbjct: 741 YFYSKFQKLLLSLKDVKMSGNWMWAAKCDGEGARLVDAVGALCRGL-REIGCAIDGGKDS 799
Query: 819 MSMKMKWDDKEVTAPLSVTITAFAPVNNTSKTWTPVLNSEAGDTILVLVDLAALQEKRSL 878
+SM + + V +P ++ ++A+AP N +K P L + G IL + + + +EK L
Sbjct: 800 LSMAVTAHGEVVKSPGTLVLSAYAPCTNVTKVVNPSLKAVPGSKIL-WIKIGSSEEKMRL 858
Query: 879 GSSAFLQVYNQIGDTAPTVHD-NKVLRGF--------LESLLDLHKTDLVLSYHDRSDGG 929
G SA QVY+QIGD P + + +++ + F E L + ++L+ HD SDGG
Sbjct: 859 GGSALAQVYSQIGDDCPDIENFSEISKVFSIVQQLLNREELAGPLRKPIILAGHDISDGG 918
Query: 930 LLVTLLEMAFASRCGLDVVIDTVKDG-NPFVPLFNEELGAVFQIKESSLSEFQSVLNAHG 988
LL +LEMAFA +D+ I P LF EE G + ++ S+ + + G
Sbjct: 919 LLTAILEMAFAGNVSIDIDIKPPNQNIKPIDILFAEECGILLEV--SNPENVLHIFSEAG 976
Query: 989 VSNEYI---SVVAKPNFAAHQITISDKAGSAIFQGTRGKLQQAWSSTSYEMQKLRDNPKT 1045
+ + I S V P+ A +I ++ G L++ W + + + NPK+
Sbjct: 977 IKCQEIGKASAVFGPD-AHVKIHVN---GHLEINEKLVDLREEWELVGDRLGEFQTNPKS 1032
Query: 1046 --TVQEFSAINDDKDPGLHYALTYNPTDDLQIGAQLSAVRPKVAILREQGVNGQMEMAWC 1103
+E + + YNP Q + P+VAI+RE+G NG EMA
Sbjct: 1033 LKEAREVRRTCQKINYKCDFDWYYNPA--FIHNEQYFSTAPRVAIIREEGSNGDREMASA 1090
Query: 1104 FQQAGFDPIDVTMTDLIGGKFNLNEFTGMAACGGFSYGDVLGAGAGWAKSVLYHEGVRKQ 1163
F AGF DVTMTD++ G L + G+A GGFSY DVLG+ GWA V ++E V KQ
Sbjct: 1091 FTLAGFQTFDVTMTDILAG-HTLEAYRGVAFVGGFSYADVLGSAKGWAAGVQFNESVSKQ 1149
Query: 1164 FVNFFQEREDTFAFGACNGCQFLSRLKSIIPGCENWPS--FERNLSEQYEARVCMVEIVQ 1221
F F+ R DTF++G CNGCQ +++L I + P+ + N ++++ V+I +
Sbjct: 1150 F-EAFRSRPDTFSYGVCNGCQLMAQLGWIGDEEQKGPTVFLDENECGRFDSSFGPVKIEK 1208
Query: 1222 DDGAEAQSVFFNGMVGSKLPIAVAHGEGKATFTDEDQLKRFEEQGLTGVRYVD------- 1274
+ S+ +GM S L + +HGEG+ T+ + + + G +R+ D
Sbjct: 1209 N-----VSIMLSGMENSVLGLWSSHGEGRFTYRNLQNFQNLKTNGQVCIRFCDDRGMTGA 1263
Query: 1275 NYGNVTEKFPFNPNGSPNGISGIKSPNGRVLAMMPHPERVCR----LESNSWYPDGKYEE 1330
++G+V +P+NPNGS + ++ I S +GR LAMMPH +R ES+ + ++++
Sbjct: 1264 DHGSVKLPYPWNPNGSIDDVAAICSRDGRHLAMMPHADRSFLTWQWAESSEVPWNARFDQ 1323
Query: 1331 -WEGYGPWIRLFRSARKW 1347
PWI++FR+A W
Sbjct: 1324 KTVALSPWIKMFRNAYNW 1341
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,557,008
Number of Sequences: 60738
Number of extensions: 3508698
Number of successful extensions: 7807
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 7731
Number of HSP's gapped (non-prelim): 5
length of query: 1349
length of database: 30,389,216
effective HSP length: 119
effective length of query: 1230
effective length of database: 23,161,394
effective search space: 28488514620
effective search space used: 28488514620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)