ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2017 good T KOG0037 Signal transduction mechanisms Ca2+-binding protein, EF-Hand protein superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2017 721240 720155 -362
(362 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR058w [T] KOG0037 Ca2+-binding protein EF-Hand protein superfa... 268 9e-72
7303734 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfa... 81 3e-15
Hs7019485 [T] KOG0037 Ca2+-binding protein EF-Hand protein super... 77 5e-14
Hs6912582 [T] KOG0037 Ca2+-binding protein EF-Hand protein super... 76 9e-14
CE12418 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfa... 71 2e-12
Hs4507207 [T] KOG0037 Ca2+-binding protein EF-Hand protein super... 63 6e-10
Hs20544511 [T] KOG0037 Ca2+-binding protein EF-Hand protein supe... 62 2e-09
Hs6912388 [T] KOG0037 Ca2+-binding protein EF-Hand protein super... 61 2e-09
7289349 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfa... 61 3e-09
Hs14161692 [T] KOG0037 Ca2+-binding protein EF-Hand protein supe... 59 8e-09
Hs4557405 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine proteas... 59 1e-08
Hs4502563 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine proteas... 59 1e-08
Hs4502565 [T] KOG0037 Ca2+-binding protein EF-Hand protein super... 55 2e-07
Hs12408656 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protea... 55 2e-07
7302479 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease ... 50 5e-06
Hs5729758 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine proteas... 49 9e-06
7294858 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease ... 49 9e-06
>YGR058w [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 335
Score = 268 bits (685), Expect = 9e-72
Identities = 147/301 (48%), Positives = 187/301 (61%), Gaps = 23/301 (7%)
Query: 76 SQPRVPSYEQPPAPSRVMAQMP---AHNG--SSASMSTYAP--------PQQVYYQSQTA 122
+Q + P+ AP + Q A NG S S +Y+P P+ + A
Sbjct: 44 TQAQTPNTRVHSAPIPLQTQYNKNRAENGHHSYGSPQSYSPRHTKTPVDPRYNVIAQKPA 103
Query: 123 GHPVATVP-HSSPQNISIRAPNPPPPRSMQSSSAPQVQYRKNQPLXXXXXXXXXXXXXXX 181
G P+ P H + N S + PP + + + P +K P
Sbjct: 104 GRPIPPAPTHYNNLNTSAQRIASSPPPLIHNQAVPAQLLKKVAP---------ASFDSRE 154
Query: 182 XXXDNLIATELFNNHDLKNMGRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTV 241
D +AT+LF+NHD+K RLTA+EL NLLQNDD S FC SS+++LINLFG SRFGTV
Sbjct: 155 DVRDMQVATQLFHNHDVKGKNRLTAEELQNLLQNDDNSHFCISSVDALINLFGASRFGTV 214
Query: 242 NLNEFISLYKRVKKWRKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAE 301
N EFI+LYKRVK WRK +VDNDINGS T++++EFH ++Q LGYLIPFEVSEK F+ YAE
Sbjct: 215 NQAEFIALYKRVKSWRKVYVDNDINGSLTISVSEFHNSLQELGYLIPFEVSEKTFDQYAE 274
Query: 302 YFDQQRLNKEMKFDRFVETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDLTLYLGKFLP 361
+ ++ KE+KFD+FVE LVWLMRLTK+FRK+D QEG ATI YKDFI TLYLG+FLP
Sbjct: 275 FINRNGTGKELKFDKFVEALVWLMRLTKLFRKFDTNQEGIATIQYKDFIYATLYLGRFLP 334
Query: 362 H 362
H
Sbjct: 335 H 335
>7303734 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 199
Score = 80.9 bits (198), Expect = 3e-15
Identities = 48/166 (28%), Positives = 82/166 (48%), Gaps = 5/166 (3%)
Query: 189 ATELFNNHDLKNMGRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTVNLNEFIS 248
A + F+ D G++ A EL L N G F ++ + +I++F GT+++ EF
Sbjct: 35 AQQWFSMVDRDRSGKINASELQAALVNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEK 94
Query: 249 LYKRVKKWRKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRL 308
LY + +W + F D + S + E +A +G F S + + D Q
Sbjct: 95 LYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMG----FRFSPEFINFLVKKSDPQG- 149
Query: 309 NKEMKFDRFVETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDLTL 354
+KE+ D+F+ V + R T+ FR+ D QQ GT TI ++DF+ + +
Sbjct: 150 HKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFLTVAI 195
>Hs7019485 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 191
Score = 76.6 bits (187), Expect = 5e-14
Identities = 43/168 (25%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Query: 185 DNLIATELFNNHDLKNMGRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTVNLN 244
D +F D G ++ EL L N + F ++ S+I++F VN +
Sbjct: 24 DQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFS 83
Query: 245 EFISLYKRVKKWRKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFD 304
EF ++K + W+ F D + S + E +A+ GY +S++ + FD
Sbjct: 84 EFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGY----RLSDQFHDILIRKFD 139
Query: 305 QQRLNKEMKFDRFVETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDL 352
+Q ++ FD F++ + L RLT +FR+YD Q+G ++Y+ ++ +
Sbjct: 140 RQG-RGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSM 186
>Hs6912582 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 284
Score = 75.9 bits (185), Expect = 9e-14
Identities = 41/161 (25%), Positives = 84/161 (51%), Gaps = 4/161 (2%)
Query: 193 FNNHDLKNMGRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTVNLNEFISLYKR 252
F + D + G ++ EL L N + S F + +IN+F ++ G +++ F +L+K
Sbjct: 123 FQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKF 182
Query: 253 VKKWRKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEM 312
+++W+ F D + S +++ E +A+ +GY + + ++ L Y + N M
Sbjct: 183 IQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYC----PRSANPAM 238
Query: 313 KFDRFVETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDLT 353
+ DRF++ L LT+ FR+ D +G ++++DF+ +T
Sbjct: 239 QLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMT 279
>CE12418 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 157
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/142 (27%), Positives = 69/142 (48%), Gaps = 5/142 (3%)
Query: 191 ELFNNHDLKNMGRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTVNLNEFISLY 250
++F++ D G++++DEL L N + F + +I +F + G +N EF +L+
Sbjct: 10 QIFSSVDKDRSGQISSDELQTALSNGTWNPFNPETCRLMIGMFDSNGDGAINFQEFQALW 69
Query: 251 KRVKKWRKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNK 310
+ + W CF D +GS + +E A+ GY +S + + FD+ N+
Sbjct: 70 RYINDWTNCFRGFDTDGSGNIDKSELTNALTQFGY----RLSPQFYNILMHKFDRSHSNR 125
Query: 311 EMKFDRFVETLVWLMRLTKVFR 332
+ FD F++ V L LT FR
Sbjct: 126 -INFDDFIQLCVVLQTLTAAFR 146
>Hs4507207 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 198
Score = 63.2 bits (152), Expect = 6e-10
Identities = 42/157 (26%), Positives = 72/157 (45%), Gaps = 11/157 (7%)
Query: 202 GRLTADELHNLLQNDD---GSK-FCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKWR 257
G++ ADEL L G K F + ++++ GT+ NEF L+ + WR
Sbjct: 47 GQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWR 106
Query: 258 KCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDRF 317
+ F+ D + S T+ E KA+ ++G+ + + + + Y+ N ++ FD +
Sbjct: 107 QHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-------TNGKITFDDY 159
Query: 318 VETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDLTL 354
+ V L LT FR+ D Q+G Y DFI +
Sbjct: 160 IACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
>Hs20544511 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 121
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/112 (27%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 241 VNLNEFISLYKRVKKWRKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYA 300
VN +EF ++K + W+ F D + S + E +A+ GY +S++ +
Sbjct: 10 VNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGY----RLSDQFHDILI 65
Query: 301 EYFDQQRLNKEMKFDRFVETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDL 352
FD+Q ++ FD F++ + L RLT +FR+YD Q+G ++Y+ ++ +
Sbjct: 66 RKFDRQGRG-QIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSM 116
>Hs6912388 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 217
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/157 (27%), Positives = 71/157 (44%), Gaps = 11/157 (7%)
Query: 202 GRLTADELHNLLQ----NDDGSKFCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKWR 257
G + A+EL L N S F + +I + G + N F L+ + W+
Sbjct: 66 GEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWK 125
Query: 258 KCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDRF 317
+ F+ D +GS T+ E +A+ +GY + + + + Y++ N + FD +
Sbjct: 126 ENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSK-------NGRIFFDDY 178
Query: 318 VETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDLTL 354
V V L LT FRK D Q+G+A Y DF+ T+
Sbjct: 179 VACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTM 215
>7289349 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 219
Score = 60.8 bits (146), Expect = 3e-09
Identities = 45/174 (25%), Positives = 74/174 (41%), Gaps = 9/174 (5%)
Query: 185 DNLIATELFNNHDLKNMGRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTVNLN 244
D ++F D G ++ADEL L N S F +I +I +F GTV+
Sbjct: 10 DQQFLWDVFQRVDKDRSGHISADELQVALSNGTWSAFNPETIRLMIGMFDRENKGTVSFK 69
Query: 245 EFISLYKRVKKWRKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFD 304
+F +L+K V W+ CF D + S + E A+ S GY +S+ L + FD
Sbjct: 70 DFGALWKYVTDWQNCFRSFDRDNSGNIDKTELKTALTSFGY----RLSDHLIDVLLRKFD 125
Query: 305 QQRLNKEMKFDRFVETLVWLMRLTKVFRKYDLQ----QEGTATIAYKDFIDLTL 354
+ + FD F++ + L V Y+ + +AY+ ++ L
Sbjct: 126 RFG-RGTILFDDFIQCCIVLYVSMTVIAIYEYKVAVGSRDFRCLAYEKIFEIAL 178
>Hs14161692 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 248
Score = 59.3 bits (142), Expect = 8e-09
Identities = 31/135 (22%), Positives = 70/135 (50%), Gaps = 6/135 (4%)
Query: 221 FCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKWRKCFVDNDINGSFTLTMAEFHKAV 280
F + S++++ G + EF L+ +KKW+ + D + S +L ++ A+
Sbjct: 119 FSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYKQYDRDHSGSLGSSQLRGAL 178
Query: 281 QSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDRFVETLVWLMRLTKVFRKYDLQQEG 340
Q+ G F+++E+L++ + + + +M F+ F+ LV L + + F+ D ++G
Sbjct: 179 QAAG----FQLNEQLYQMIVRRYANE--DGDMDFNNFISCLVRLDAMFRAFKSLDRDRDG 232
Query: 341 TATIAYKDFIDLTLY 355
++ K+++ LT+Y
Sbjct: 233 LIQVSIKEWLQLTMY 247
>Hs4557405 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease (calpain)
large subunit (EF-Hand protein superfamily)
Length = 821
Score = 58.9 bits (141), Expect = 1e-08
Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 6/135 (4%)
Query: 221 FCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKWRKCFVDNDINGSFTLTMAEFHKAV 280
F S S+I L G +NL EF L+ ++K W+K F D + S T+ E AV
Sbjct: 692 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 751
Query: 281 QSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDRFVETLVWLMRLTKVFRKYDLQQEG 340
G F ++ +L++ + + +N + FD F+ V L + + F +D +G
Sbjct: 752 NDAG----FHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDG 805
Query: 341 TATIAYKDFIDLTLY 355
+ +++ LT+Y
Sbjct: 806 IIKLNVLEWLQLTMY 820
>Hs4502563 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease (calpain)
large subunit (EF-Hand protein superfamily)
Length = 700
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/145 (25%), Positives = 74/145 (50%), Gaps = 13/145 (8%)
Query: 204 LTADELHNLL-------QNDDGSKFCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKW 256
++A EL +L Q+ F + + ++++ G + L EF L+ +++K+
Sbjct: 548 ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKY 607
Query: 257 RKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDR 316
+K + + D++ S T+ E KA++ G+ +P ++ + + A + D Q + + FD
Sbjct: 608 QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIV---ARFADDQLI---IDFDN 661
Query: 317 FVETLVWLMRLTKVFRKYDLQQEGT 341
FV LV L L K+F++ D + GT
Sbjct: 662 FVRCLVRLETLFKIFKQLDPENTGT 686
>Hs4502565 [T] KOG0037 Ca2+-binding protein EF-Hand protein superfamily
Length = 268
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/214 (20%), Positives = 80/214 (36%), Gaps = 24/214 (11%)
Query: 142 PNPPPPRSMQSSSAPQVQYRKNQPLXXXXXXXXXXXXXXXXXXDNLIATELFNNHDLKNM 201
P PPPPR+ S+ Q N++ + + DLK
Sbjct: 78 PEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTD 137
Query: 202 GRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKWRKCFV 261
G F + S++ + G + EF L+ +K+W+ +
Sbjct: 138 G------------------FGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYK 179
Query: 262 DNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDRFVETL 321
D + S T+ +E A ++ G F ++E L+ + + N M FD F+ L
Sbjct: 180 QFDTDRSGTICSSELPGAFEAAG----FHLNEHLYNMIIRRYSDESGN--MDFDNFISCL 233
Query: 322 VWLMRLTKVFRKYDLQQEGTATIAYKDFIDLTLY 355
V L + + F+ D G + ++++ LT+Y
Sbjct: 234 VRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMY 267
>Hs12408656 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease (calpain)
large subunit (EF-Hand protein superfamily)
Length = 714
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/135 (26%), Positives = 66/135 (48%), Gaps = 6/135 (4%)
Query: 221 FCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKWRKCFVDNDINGSFTLTMAEFHKAV 280
F S S++NL G + L EF L+ R++ + F D++ S +++ E A+
Sbjct: 585 FSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAI 644
Query: 281 QSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDRFVETLVWLMRLTKVFRKYDLQQEG 340
+S G F++++KL+E + + L + FD FV LV L + + F+ D +G
Sbjct: 645 ESAG----FKLNKKLYELIITRYSEPDL--AVDFDNFVCCLVRLETMFRFFKTLDTDLDG 698
Query: 341 TATIAYKDFIDLTLY 355
T ++ LT++
Sbjct: 699 VVTFDLFKWLQLTMF 713
>7302479 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease (calpain)
large subunit (EF-Hand protein superfamily)
Length = 828
Score = 50.1 bits (118), Expect = 5e-06
Identities = 30/140 (21%), Positives = 62/140 (43%), Gaps = 6/140 (4%)
Query: 216 DDGSKFCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKWRKCFVDNDINGSFTLTMAE 275
D+ F S++ + + G + EF +L + KW+ F D+ + ++ +
Sbjct: 694 DETHGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQ 753
Query: 276 FHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDRFVETLVWLMRLTKVFRKYD 335
+A+ S GY + V L Y + ++ FD F+ V + +F++ D
Sbjct: 754 LREALNSAGYHLNNRVLNVLGHRYGS------RDGKIAFDDFIMCAVKIKTYIDIFKERD 807
Query: 336 LQQEGTATIAYKDFIDLTLY 355
++ TAT +++I+ T+Y
Sbjct: 808 TEKNETATFTLEEWIERTIY 827
>Hs5729758 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease (calpain)
large subunit (EF-Hand protein superfamily)
Length = 690
Score = 49.3 bits (116), Expect = 9e-06
Identities = 40/158 (25%), Positives = 78/158 (49%), Gaps = 13/158 (8%)
Query: 204 LTADEL----HNLLQNDDGSKFCTSSI---ESLINLFGGSRFGTVNLNEFISLYKRVKKW 256
+TA+EL + +LQ KF S+ +++I+L S G + +EF + ++K+W
Sbjct: 537 VTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQW 596
Query: 257 RKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDR 316
F+ D + S T++ E A+++ G F++S L + + + L ++ FD
Sbjct: 597 INLFLRFDADKSGTMSTYELRTALKAAG----FQLSSHLLQLIVLRYADEEL--QLDFDD 650
Query: 317 FVETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDLTL 354
F+ LV L ++VF+ + + + +FI LT+
Sbjct: 651 FLNCLVRLENASRVFQALSTKNKEFIHLNINEFIHLTM 688
>7294858 [OT] KOG0045 Cytosolic Ca2+-dependent cysteine protease (calpain)
large subunit (EF-Hand protein superfamily)
Length = 791
Score = 49.3 bits (116), Expect = 9e-06
Identities = 33/159 (20%), Positives = 69/159 (42%), Gaps = 8/159 (5%)
Query: 197 DLKNMGRLTADELHNLLQNDDGSKFCTSSIESLINLFGGSRFGTVNLNEFISLYKRVKKW 256
D + + R+ + +++ DG F ++ S++ + R G + EF +L + KW
Sbjct: 640 DWQELKRILDHSMRDVMVGSDG--FSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKW 697
Query: 257 RKCFVDNDINGSFTLTMAEFHKAVQSLGYLIPFEVSEKLFECYAEYFDQQRLNKEMKFDR 316
R F D + ++ A+ S GY ++ +L A + + ++ FD
Sbjct: 698 RAVFKLYDTRRTGSIDGFHLRGALNSAGY----HLNNRLLNALAHRYGSR--EGQIPFDD 751
Query: 317 FVETLVWLMRLTKVFRKYDLQQEGTATIAYKDFIDLTLY 355
F+ + + ++FR+ D TA D+++ T+Y
Sbjct: 752 FLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLERTIY 790
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,716,638
Number of Sequences: 60738
Number of extensions: 965710
Number of successful extensions: 5943
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 5920
Number of HSP's gapped (non-prelim): 19
length of query: 362
length of database: 30,389,216
effective HSP length: 108
effective length of query: 254
effective length of database: 23,829,512
effective search space: 6052696048
effective search space used: 6052696048
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)