ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2026 good R KOG1944 General function prediction only Peroxisomal membrane protein MPV17 and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2026 723299 724288 330
(330 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR292c [R] KOG1944 Peroxisomal membrane protein MPV17 and relat... 298 7e-81
SPAC3G6.05 [R] KOG1944 Peroxisomal membrane protein MPV17 and re... 91 2e-18
SPAC4G9.14 [R] KOG1944 Peroxisomal membrane protein MPV17 and re... 85 2e-16
YLR251w [R] KOG1944 Peroxisomal membrane protein MPV17 and relat... 63 5e-10
Hs4505241 [R] KOG1944 Peroxisomal membrane protein MPV17 and rel... 61 2e-09
Hs8923892 [R] KOG1944 Peroxisomal membrane protein MPV17 and rel... 60 3e-09
7294657 [R] KOG1944 Peroxisomal membrane protein MPV17 and relat... 57 3e-08
7304363 [R] KOG1944 Peroxisomal membrane protein MPV17 and relat... 57 5e-08
7290168 [R] KOG1944 Peroxisomal membrane protein MPV17 and relat... 55 1e-07
At4g04470 [R] KOG1944 Peroxisomal membrane protein MPV17 and rel... 54 2e-07
7296797 [R] KOG1944 Peroxisomal membrane protein MPV17 and relat... 51 2e-06
At5g19750 [R] KOG1944 Peroxisomal membrane protein MPV17 and rel... 50 5e-06
>YOR292c [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 309
Score = 298 bits (763), Expect = 7e-81
Identities = 151/299 (50%), Positives = 191/299 (63%), Gaps = 24/299 (8%)
Query: 29 WKTITLNLIYSLRRFKILKITIIHWSILSTWIVLLLHFTSVYGSLYQSSALLATMCTNVL 88
W + +L +I +IT+ HW +L W+ L FTS Y LY +SA+ AT+CTN+L
Sbjct: 34 WTRRAAAALRTLMNKRIQRITLTHWLLLVIWVTSLWKFTSHYRQLYANSAVFATLCTNIL 93
Query: 89 LFGTSDCLAQCISCFLSYXXXXXXXXXXXXTRNLVAGLSFRRTESFDDNYSDNVSIFNDY 148
LFG SD LAQ I+CF SY ++ R E+ SD +SIFND+
Sbjct: 94 LFGISDILAQSIACFYSYHVDPIPQILNDTFHHVQNN---RDVENGGGYESDELSIFNDF 150
Query: 149 GVERPSFEGQTDTRNASPGIDSELRHDWDLDSNLDYDADGTSSSNNELFSFYRWICFMSW 208
E S+ D P +D L ++ + F F+RW CFM W
Sbjct: 151 TSEHSSYTDNDDY----PELDRPL-----------------ATFKTDTFDFFRWGCFMFW 189
Query: 209 GWFLSFFQVPWYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISLYCFFMYSNYIMEHGDA 268
G+F+SFFQ PWYKFLN+FYTEDPTVVQV ERVLSDQL+YSPISLYCFFM+SNY+ME GD
Sbjct: 190 GFFISFFQAPWYKFLNFFYTEDPTVVQVFERVLSDQLLYSPISLYCFFMFSNYVMEGGDK 249
Query: 269 ESFQIKIRNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLSMRNSS 327
++ KI+ +YI+TLGCNYLVWP+VQFINFL++P+ Q PFSSSVGV+WNCFLSMRN+S
Sbjct: 250 DTLGKKIQRLYISTLGCNYLVWPMVQFINFLIMPRDFQAPFSSSVGVVWNCFLSMRNAS 308
>SPAC3G6.05 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 206
Score = 91.3 bits (225), Expect = 2e-18
Identities = 44/138 (31%), Positives = 82/138 (58%), Gaps = 1/138 (0%)
Query: 191 SSNNELFSFYRWICFMSWGWFLSFFQVPWYKFLNYFYTEDPTVVQVLERVLSDQLVYSPI 250
+++ E+ S R + F+++G+ +S FQ W + L+ + + + V++RVL DQ V++P
Sbjct: 58 NTHPEIPSIKRVLQFVTFGFAISPFQFRWLRLLSAKFPIEKGAINVVKRVLLDQAVFAPF 117
Query: 251 SLYCFFMYSNYIMEHGDAESFQIKIRNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFS 310
FF + G ++ K++ ++ TL NY+VWP Q +NF ++P Q+PF+
Sbjct: 118 GTAFFFSWMTLAEGKGFRGAYD-KLQAVFWPTLKANYMVWPFFQTVNFWLMPLQYQMPFA 176
Query: 311 SSVGVLWNCFLSMRNSSN 328
+V + WN FLS++N+S+
Sbjct: 177 CTVAIFWNIFLSLKNASS 194
>SPAC4G9.14 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 221
Score = 84.7 bits (208), Expect = 2e-16
Identities = 48/129 (37%), Positives = 74/129 (57%), Gaps = 3/129 (2%)
Query: 200 YRWICFMSWGWFLSFFQVPWYKFL-NYFYTEDPTVVQVLERVLSDQLVYSPISLYCFFMY 258
+R I + ++G L+ Q W+ L N TE+P + VL RV DQ +++P+ + FF++
Sbjct: 90 HRTIRYAAYGLCLTPIQFRWFVALSNVIQTENPFIAIVL-RVALDQFIFAPLGIVFFFLF 148
Query: 259 SNYIMEHGDAESFQIKIRNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWN 318
I E E + R Y TL NY++WP VQ NF VP LQV F+++V ++W
Sbjct: 149 MG-ITECKSYERLKSYFRKHYWPTLKANYILWPAVQLFNFTFVPLVLQVIFANAVSMVWT 207
Query: 319 CFLSMRNSS 327
+LS++NSS
Sbjct: 208 AYLSLKNSS 216
>YLR251w [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 197
Score = 63.2 bits (152), Expect = 5e-10
Identities = 41/118 (34%), Positives = 62/118 (51%), Gaps = 5/118 (4%)
Query: 213 SFFQVPWYKFLN--YFYTEDPTV--VQVLERVLSDQLVYSPISLYCFFMYSNYIMEHGDA 268
SF WYK LN + P ++ RV DQL ++P+ L +F + IME
Sbjct: 64 SFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAFAPLGLPFYFTCMS-IMEGRSF 122
Query: 269 ESFQIKIRNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLSMRNS 326
+ ++KI+ + TL N+ VWPL Q INF +VP ++ + V + WN +LS +NS
Sbjct: 123 DVAKLKIKEQWWPTLLTNWAVWPLFQAINFSVVPLQHRLLAVNVVAIFWNTYLSYKNS 180
>Hs4505241 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 176
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/106 (33%), Positives = 53/106 (49%), Gaps = 2/106 (1%)
Query: 219 WYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISLYCFFMYSNYIMEHGDAESFQIKIRNI 278
WYK L+ F T V L+++L DQ ++P L CF + A+ K++
Sbjct: 69 WYKVLDRFIP-GTTKVDALKKMLLDQGGFAPCFLGCFLPLVG-ALNGLSAQDNWAKLQRD 126
Query: 279 YITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLSMR 324
Y L NY +WP VQ NF +VP H ++ V V+WN +LS +
Sbjct: 127 YPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWK 172
>Hs8923892 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 195
Score = 60.5 bits (145), Expect = 3e-09
Identities = 39/113 (34%), Positives = 59/113 (51%), Gaps = 6/113 (5%)
Query: 214 FFQVPWYKFLNYFYTEDPTVVQV----LERVLSDQLVYSPISLYCFFMYSNYIMEHGDAE 269
FF P F YF+ E +V L R+L D+LV++P L FF+ N++ E DA
Sbjct: 81 FFTGPLSHFF-YFFMEHWIPPEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFL-EGKDAS 138
Query: 270 SFQIKIRNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLS 322
+F K+R + L N+ VW +QFIN VP +V F++ + W +L+
Sbjct: 139 AFAAKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLA 191
>7294657 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 196
Score = 57.4 bits (137), Expect = 3e-08
Identities = 30/104 (28%), Positives = 57/104 (53%), Gaps = 2/104 (1%)
Query: 219 WYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISLYCFFMYSNYIMEHGDAESFQIKIRNI 278
WY+ L+Y + + T V+ ++L DQ + SP + FF+ + I+E E + +IR
Sbjct: 81 WYQHLDYLFPKR-TYKVVVVKILLDQFICSPFYIAVFFL-TMAILEDNTWEELEQEIREK 138
Query: 279 YITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLS 322
+ + VWPL QFINFL++ +V + +++ + ++ + S
Sbjct: 139 ALVLYAAEWTVWPLAQFINFLLIKPQYRVFYDNTISLGYDIYTS 182
>7304363 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 168
Score = 56.6 bits (135), Expect = 5e-08
Identities = 31/108 (28%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Query: 219 WYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISLYCFFMYSNYIMEHGDAESF---QIKI 275
WY FL + P + R ++ LV + F M ++++ + E + +I
Sbjct: 60 WYHFLE---SRVPKTYSPMRRGVTKMLVDQTLFAPPFTMAMSFLVPLSNGEPIDRIRQRI 116
Query: 276 RNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLSM 323
+ Y++ L NY++WP Q +NF VP QV ++ + ++WNC+LSM
Sbjct: 117 LDSYLSILVRNYMLWPAAQMLNFRFVPLGYQVLYAQFIALVWNCYLSM 164
>7290168 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 186
Score = 55.5 bits (132), Expect = 1e-07
Identities = 31/127 (24%), Positives = 60/127 (46%), Gaps = 6/127 (4%)
Query: 200 YRWICFMSWGWFLSFFQVP----WYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISLYCF 255
Y W + + + F P W K + + + V++ + + + Y+P ++ CF
Sbjct: 48 YDWWRVLRFSMYGGLFVAPTLYGWVKISSAMWPQTSLRTGVIKAAV-ETISYTPGAMTCF 106
Query: 256 FMYSNYIMEHGDAESFQIKIRNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGV 315
+ + ++E E ++ ++ T VWPLV INF ++P+ +VPF S+ +
Sbjct: 107 YFIMS-LLESKTVEQAVAEVGKKFLPTYKVALSVWPLVATINFTLIPERNRVPFISACSL 165
Query: 316 LWNCFLS 322
W CFL+
Sbjct: 166 CWTCFLA 172
>At4g04470 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 190
Score = 54.3 bits (129), Expect = 2e-07
Identities = 30/112 (26%), Positives = 56/112 (49%)
Query: 219 WYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISLYCFFMYSNYIMEHGDAESFQIKIRNI 278
++ +L+ F+ V ++V+ +QL SP++ F +Y ++E + +I+
Sbjct: 73 FHTYLDKFFKGKKDTQTVAKKVILEQLTLSPLNHLLFMIYYGVVIERTPWTLVRERIKKT 132
Query: 279 YITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLSMRNSSNSL 330
Y T + +P+V +IN+ VP H +V S V W FL++R S +L
Sbjct: 133 YPTVQLTAWTFFPVVGWINYKYVPLHFRVILHSLVAFFWGIFLTLRARSMTL 184
>7296797 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 193
Score = 51.2 bits (121), Expect = 2e-06
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 6/130 (4%)
Query: 197 FSFYRWICFMSWGWFLSFFQVP----WYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISL 252
F Y W+ + + F FF P W + + + + L + +++Q Y P+++
Sbjct: 41 FRTYDWMKCLRFSLFGFFFMGPTIYVWIRLASVMWPRTD-IKSSLCKAITEQTAYDPMAI 99
Query: 253 YCFFMYSNYIMEHGDAESFQIKIRNIYITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSS 312
F + +ME + ++ + ++ + WP VQ +NF VP QV F+S
Sbjct: 100 SSFLFFMT-LMEGNSYAEAKREVNDKFLDAYKVGVIYWPCVQTVNFAFVPARNQVVFTSF 158
Query: 313 VGVLWNCFLS 322
+ W FL+
Sbjct: 159 FSMCWTTFLA 168
>At5g19750 [R] KOG1944 Peroxisomal membrane protein MPV17 and related proteins
Length = 288
Score = 50.1 bits (118), Expect = 5e-06
Identities = 32/106 (30%), Positives = 53/106 (49%), Gaps = 3/106 (2%)
Query: 219 WYKFLNYFYTEDPTVVQVLERVLSDQLVYSPISLYCFFMYSNYIMEHGDAESFQIKIRNI 278
WY +L+ T V+ R+L DQ V++PI + F S + G + K++
Sbjct: 178 WYLYLSKVVTASGLSGAVI-RLLLDQFVFAPIFVGVFL--SAVVTLEGKPSNVIPKLQQE 234
Query: 279 YITTLGCNYLVWPLVQFINFLMVPKHLQVPFSSSVGVLWNCFLSMR 324
+ + N+ +W QF+NF VP++ QV S+ V + WN LS +
Sbjct: 235 WTGAMIANWQLWIPFQFLNFRFVPQNYQVLASNVVALAWNVILSFK 280
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.138 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,511,215
Number of Sequences: 60738
Number of extensions: 801424
Number of successful extensions: 2407
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2393
Number of HSP's gapped (non-prelim): 12
length of query: 330
length of database: 30,389,216
effective HSP length: 107
effective length of query: 223
effective length of database: 23,890,250
effective search space: 5327525750
effective search space used: 5327525750
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)