ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2454 check: MH R KOG0594 General function prediction only Protein kinase PCTAIRE and related kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2454 856214 855330 -295
(295 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 535 e-152
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 390 e-108
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 389 e-108
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 379 e-105
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 379 e-105
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 377 e-105
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 373 e-103
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 350 2e-96
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 340 1e-93
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 333 2e-91
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 330 1e-90
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 327 1e-89
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 317 2e-86
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 317 2e-86
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 310 1e-84
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 309 3e-84
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 308 6e-84
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 307 1e-83
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 306 2e-83
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 305 7e-83
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 297 1e-80
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 296 2e-80
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 296 2e-80
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 293 2e-79
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 285 7e-77
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 273 2e-73
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 267 1e-71
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 267 1e-71
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 266 3e-71
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 4e-71
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 6e-71
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 265 6e-71
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 265 6e-71
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 264 1e-70
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 264 1e-70
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 264 1e-70
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 264 1e-70
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 264 1e-70
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 264 1e-70
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 260 1e-69
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 258 9e-69
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 256 2e-68
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 255 6e-68
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 255 6e-68
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 251 7e-67
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 251 7e-67
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 245 6e-65
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 244 8e-65
CE26422 [D] KOG0600 Cdc2-related protein kinase 241 9e-64
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 240 2e-63
At5g10270 [D] KOG0600 Cdc2-related protein kinase 239 3e-63
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 238 1e-62
7296451 [D] KOG0600 Cdc2-related protein kinase 237 1e-62
At5g64960 [D] KOG0600 Cdc2-related protein kinase 235 5e-62
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 234 8e-62
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 234 8e-62
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 234 8e-62
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 231 1e-60
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 231 1e-60
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 231 1e-60
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 229 4e-60
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 229 5e-60
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 223 2e-58
YKL139w [D] KOG0600 Cdc2-related protein kinase 219 5e-57
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 218 1e-56
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
YPR161c [D] KOG0600 Cdc2-related protein kinase 216 4e-56
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 216 4e-56
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 214 1e-55
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 214 1e-55
At1g03740 [D] KOG0600 Cdc2-related protein kinase 214 1e-55
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 213 2e-55
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 213 3e-55
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 209 3e-54
At5g44290 [D] KOG0600 Cdc2-related protein kinase 209 3e-54
At1g33770 [D] KOG0600 Cdc2-related protein kinase 208 8e-54
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 203 2e-52
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 203 3e-52
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 202 4e-52
At5g50860 [D] KOG0600 Cdc2-related protein kinase 202 5e-52
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 202 6e-52
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 201 1e-51
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 201 1e-51
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 200 2e-51
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 200 2e-51
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 200 2e-51
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 199 5e-51
At4g10010 [D] KOG0600 Cdc2-related protein kinase 198 7e-51
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 198 9e-51
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 198 9e-51
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 195 7e-50
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 194 2e-49
At1g71530 [D] KOG0600 Cdc2-related protein kinase 194 2e-49
At1g09600 [D] KOG0600 Cdc2-related protein kinase 194 2e-49
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 192 5e-49
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 192 6e-49
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 191 8e-49
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 191 1e-48
At4g22940 [D] KOG0600 Cdc2-related protein kinase 191 1e-48
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 191 1e-48
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 191 1e-48
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 190 2e-48
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 189 3e-48
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 189 3e-48
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 189 3e-48
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 189 3e-48
At1g57700 [D] KOG0600 Cdc2-related protein kinase 189 4e-48
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 189 5e-48
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 189 5e-48
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 189 5e-48
At1g74330 [D] KOG0600 Cdc2-related protein kinase 188 7e-48
At1g54610 [D] KOG0600 Cdc2-related protein kinase 188 7e-48
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 188 9e-48
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 187 1e-47
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 187 1e-47
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 187 1e-47
At1g53050 [D] KOG0600 Cdc2-related protein kinase 187 2e-47
At3g05050 [D] KOG0600 Cdc2-related protein kinase 187 2e-47
CE24971 [T] KOG0660 Mitogen-activated protein kinase 186 3e-47
CE01583 [T] KOG0660 Mitogen-activated protein kinase 186 3e-47
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 186 3e-47
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 186 3e-47
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 186 4e-47
At5g39420 [D] KOG0600 Cdc2-related protein kinase 185 6e-47
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 184 1e-46
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 184 1e-46
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 184 2e-46
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 184 2e-46
YLR113w [T] KOG0660 Mitogen-activated protein kinase 182 4e-46
At1g18670 [D] KOG0600 Cdc2-related protein kinase 182 4e-46
YBL016w [T] KOG0660 Mitogen-activated protein kinase 179 4e-45
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 179 4e-45
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 178 7e-45
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 178 7e-45
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 177 2e-44
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 177 2e-44
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 177 2e-44
7298087 [T] KOG0660 Mitogen-activated protein kinase 176 4e-44
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 175 6e-44
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 175 6e-44
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 175 8e-44
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 175 8e-44
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 175 8e-44
7291043 [T] KOG0660 Mitogen-activated protein kinase 175 8e-44
CE29020 [T] KOG0660 Mitogen-activated protein kinase 174 1e-43
7301110 [T] KOG0660 Mitogen-activated protein kinase 174 1e-43
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 174 1e-43
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 174 1e-43
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 174 2e-43
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 174 2e-43
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 172 7e-43
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 172 7e-43
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 171 1e-42
CE06762 [T] KOG0660 Mitogen-activated protein kinase 170 2e-42
CE06686 [T] KOG0660 Mitogen-activated protein kinase 169 4e-42
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 168 7e-42
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 168 7e-42
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 168 7e-42
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 167 2e-41
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 167 2e-41
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 167 2e-41
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 164 1e-40
YHR030c [T] KOG0660 Mitogen-activated protein kinase 164 1e-40
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 164 1e-40
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 162 7e-40
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 162 7e-40
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 162 7e-40
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 162 7e-40
YGR040w [T] KOG0660 Mitogen-activated protein kinase 161 9e-40
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 161 9e-40
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 159 3e-39
YPR054w [T] KOG0660 Mitogen-activated protein kinase 159 5e-39
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 158 8e-39
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 156 4e-38
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 155 7e-38
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 155 9e-38
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 154 1e-37
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 152 6e-37
YKL161c [T] KOG0660 Mitogen-activated protein kinase 152 7e-37
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 151 9e-37
CE08727 [G] KOG0658 Glycogen synthase kinase-3 151 9e-37
CE21401 [G] KOG0658 Glycogen synthase kinase-3 151 1e-36
YMR139w [G] KOG0658 Glycogen synthase kinase-3 150 3e-36
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 150 3e-36
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 150 3e-36
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 150 3e-36
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 150 3e-36
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 149 4e-36
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 149 4e-36
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 149 5e-36
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 149 5e-36
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 149 6e-36
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 149 6e-36
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 149 6e-36
7290342 [G] KOG0658 Glycogen synthase kinase-3 149 6e-36
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 148 1e-35
CE27220 [T] KOG0660 Mitogen-activated protein kinase 147 2e-35
CE17062 [T] KOG0660 Mitogen-activated protein kinase 147 2e-35
CE29318 [T] KOG0660 Mitogen-activated protein kinase 146 3e-35
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 146 4e-35
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 146 4e-35
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 145 9e-35
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 1e-34
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 1e-34
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 1e-34
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 144 2e-34
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 142 4e-34
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 141 1e-33
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 140 2e-33
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 4e-33
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 139 5e-33
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 139 5e-33
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 137 2e-32
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 135 7e-32
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 135 9e-32
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 135 9e-32
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 134 1e-31
YDL079c [G] KOG0658 Glycogen synthase kinase-3 134 2e-31
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 134 2e-31
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 134 2e-31
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 134 2e-31
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 134 2e-31
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 133 3e-31
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 133 3e-31
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 132 6e-31
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 129 4e-30
YNL307c [G] KOG0658 Glycogen synthase kinase-3 129 7e-30
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 129 7e-30
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 127 2e-29
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 127 2e-29
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 125 7e-29
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 124 1e-28
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 124 2e-28
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 123 3e-28
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 123 4e-28
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 122 5e-28
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 122 5e-28
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 121 1e-27
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 121 1e-27
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 120 2e-27
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 119 5e-27
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 119 7e-27
CE20405 [G] KOG0658 Glycogen synthase kinase-3 116 4e-26
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 115 6e-26
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 115 6e-26
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 115 6e-26
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 115 6e-26
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 115 6e-26
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 114 2e-25
7298004 [G] KOG0658 Glycogen synthase kinase-3 114 2e-25
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 114 2e-25
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 114 2e-25
CE23001 [R] KOG0589 Serine/threonine protein kinase 114 2e-25
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 113 4e-25
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 113 4e-25
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 113 4e-25
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 113 4e-25
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 113 4e-25
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 113 4e-25
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 112 5e-25
CE05866 [G] KOG0658 Glycogen synthase kinase-3 112 6e-25
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 8e-25
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 112 8e-25
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 111 1e-24
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 111 1e-24
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 111 1e-24
YOL128c [G] KOG0658 Glycogen synthase kinase-3 110 2e-24
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 110 2e-24
CE09532 [G] KOG0658 Glycogen synthase kinase-3 110 2e-24
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 110 3e-24
CE05377 [G] KOG0658 Glycogen synthase kinase-3 110 3e-24
YDR477w [T] KOG0583 Serine/threonine protein kinase 109 4e-24
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 109 4e-24
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 109 5e-24
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 108 9e-24
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 108 9e-24
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 108 9e-24
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 108 9e-24
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 108 1e-23
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 108 1e-23
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 107 2e-23
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 107 3e-23
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 106 5e-23
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 105 6e-23
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 105 8e-23
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 8e-23
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 105 8e-23
At5g39440 [T] KOG0583 Serine/threonine protein kinase 105 1e-22
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 105 1e-22
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 104 2e-22
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 103 2e-22
At3g01090 [T] KOG0583 Serine/threonine protein kinase 103 2e-22
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 103 2e-22
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 103 3e-22
CE18454 [T] KOG4717 Serine/threonine protein kinase 103 3e-22
At3g20860 [R] KOG0589 Serine/threonine protein kinase 103 3e-22
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 103 4e-22
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 103 4e-22
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 102 5e-22
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 102 5e-22
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 102 5e-22
SPAC1D4.06c [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 7e-22
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 102 7e-22
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 102 7e-22
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 102 7e-22
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 102 7e-22
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 102 9e-22
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 102 9e-22
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 102 9e-22
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 102 9e-22
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 102 9e-22
At4g18700 [T] KOG0583 Serine/threonine protein kinase 102 9e-22
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 102 9e-22
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 101 1e-21
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 101 1e-21
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 101 1e-21
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 101 1e-21
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 100 2e-21
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 100 2e-21
CE28643 [T] KOG0583 Serine/threonine protein kinase 100 2e-21
CE07458 [T] KOG0583 Serine/threonine protein kinase 100 2e-21
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 2e-21
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 100 2e-21
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 2e-21
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 100 2e-21
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 100 2e-21
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 100 3e-21
7303211 [T] KOG4717 Serine/threonine protein kinase 100 3e-21
7301213 [R] KOG0589 Serine/threonine protein kinase 100 3e-21
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 100 4e-21
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 100 4e-21
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 100 4e-21
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 100 4e-21
YHR102w [T] KOG0201 Serine/threonine protein kinase 99 6e-21
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 99 6e-21
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 99 6e-21
At4g30960 [T] KOG0583 Serine/threonine protein kinase 99 6e-21
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 99 7e-21
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 99 7e-21
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 99 7e-21
At3g29160 [T] KOG0583 Serine/threonine protein kinase 99 7e-21
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 99 9e-21
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 99 9e-21
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 98 1e-20
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 98 1e-20
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 98 2e-20
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 98 2e-20
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 98 2e-20
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 98 2e-20
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 98 2e-20
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 97 2e-20
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 97 2e-20
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 97 2e-20
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 97 2e-20
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 97 2e-20
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 97 3e-20
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 97 3e-20
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 97 3e-20
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 97 3e-20
CE01612 [G] KOG0658 Glycogen synthase kinase-3 97 3e-20
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 97 4e-20
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 97 4e-20
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 97 4e-20
CE27177 [T] KOG4279 Serine/threonine protein kinase 97 4e-20
At5g45810 [T] KOG0583 Serine/threonine protein kinase 97 4e-20
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 97 4e-20
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 97 4e-20
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 96 5e-20
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 96 5e-20
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 96 5e-20
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 96 5e-20
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 96 5e-20
YDR507c [D] KOG0588 Serine/threonine protein kinase 96 6e-20
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 96 6e-20
At5g35410 [T] KOG0583 Serine/threonine protein kinase 96 6e-20
At2g45490 [D] KOG0580 Serine/threonine protein kinase 96 6e-20
At2g30360 [T] KOG0583 Serine/threonine protein kinase 96 6e-20
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 96 6e-20
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 96 8e-20
At2g38490 [T] KOG0583 Serine/threonine protein kinase 96 8e-20
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 96 8e-20
7299793 [T] KOG0583 Serine/threonine protein kinase 96 8e-20
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 95 1e-19
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 95 1e-19
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 95 1e-19
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 1e-19
At1g29230 [T] KOG0583 Serine/threonine protein kinase 95 1e-19
7299438 [R] KOG0586 Serine/threonine protein kinase 95 1e-19
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 95 1e-19
CE28218 [D] KOG0588 Serine/threonine protein kinase 95 1e-19
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 95 1e-19
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 94 2e-19
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 94 2e-19
CE24761 [D] KOG0580 Serine/threonine protein kinase 94 2e-19
7297776 [D] KOG0580 Serine/threonine protein kinase 94 2e-19
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 94 2e-19
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 94 2e-19
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 94 2e-19
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 94 2e-19
YDR523c [T] KOG0201 Serine/threonine protein kinase 94 3e-19
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 94 3e-19
CE28674 [T] KOG0201 Serine/threonine protein kinase 94 3e-19
CE07510 [T] KOG0201 Serine/threonine protein kinase 94 3e-19
CE00847 [T] KOG0583 Serine/threonine protein kinase 94 3e-19
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 94 3e-19
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 94 3e-19
7299437 [R] KOG0586 Serine/threonine protein kinase 94 3e-19
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 93 4e-19
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 93 4e-19
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 93 4e-19
At4g32830 [D] KOG0580 Serine/threonine protein kinase 93 4e-19
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 93 4e-19
7300224 [T] KOG0201 Serine/threonine protein kinase 93 4e-19
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 93 4e-19
YPL150w [T] KOG0583 Serine/threonine protein kinase 93 5e-19
YCL024w [T] KOG0583 Serine/threonine protein kinase 93 5e-19
At1g77720 [D] KOG0596 Dual specificity; serine/threonine and tyr... 93 5e-19
7290150 [T] KOG0583 Serine/threonine protein kinase 93 5e-19
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 92 7e-19
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 92 7e-19
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 92 7e-19
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 92 7e-19
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 92 7e-19
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 92 7e-19
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 92 7e-19
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 92 7e-19
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 92 7e-19
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 92 7e-19
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 92 7e-19
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 92 9e-19
At4g24400 [T] KOG0583 Serine/threonine protein kinase 92 9e-19
7302570 [R] KOG0586 Serine/threonine protein kinase 92 9e-19
At1g54510 [R] KOG0589 Serine/threonine protein kinase 92 1e-18
At1g53165 [T] KOG0201 Serine/threonine protein kinase 92 1e-18
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 92 1e-18
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 91 2e-18
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 91 2e-18
At3g15220 [T] KOG0201 Serine/threonine protein kinase 91 2e-18
At1g30270 [T] KOG0583 Serine/threonine protein kinase 91 2e-18
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 91 2e-18
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 91 2e-18
At3g04810 [R] KOG0589 Serine/threonine protein kinase 91 2e-18
At2g25090 [T] KOG0583 Serine/threonine protein kinase 91 2e-18
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 91 2e-18
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 91 2e-18
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 91 3e-18
At5g28290 [R] KOG0589 Serine/threonine protein kinase 91 3e-18
At5g20930 [T] KOG1151 Tousled-like protein kinase 91 3e-18
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 91 3e-18
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 90 3e-18
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 90 3e-18
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 90 3e-18
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 90 3e-18
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 90 3e-18
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 90 3e-18
CE21025 [D] KOG0580 Serine/threonine protein kinase 90 3e-18
At5g10930 [T] KOG0583 Serine/threonine protein kinase 90 3e-18
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 90 3e-18
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 90 4e-18
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 89 6e-18
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 89 6e-18
At5g25110 [T] KOG0583 Serine/threonine protein kinase 89 6e-18
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 6e-18
At2g25880 [D] KOG0580 Serine/threonine protein kinase 89 6e-18
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 89 6e-18
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 89 7e-18
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 89 7e-18
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 89 7e-18
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 89 7e-18
CE27768 [R] KOG0586 Serine/threonine protein kinase 89 7e-18
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 7e-18
CE23838 [R] KOG0586 Serine/threonine protein kinase 89 7e-18
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 89 7e-18
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 89 7e-18
Hs4826776 [T] KOG0197 Tyrosine kinases 89 1e-17
7302464 [R] KOG0586 Serine/threonine protein kinase 89 1e-17
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 88 1e-17
Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (... 88 1e-17
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 1e-17
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 88 1e-17
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 1e-17
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 1e-17
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 535 bits (1378), Expect = e-152
Identities = 257/294 (87%), Positives = 276/294 (93%), Gaps = 2/294 (0%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLR--HQNRVVAMKKIRLESEDEGVPSTAIREISLLK 60
EL NYKRLEKVGEGTYGVVYKA+DLR RVVA+KKIRLESEDEGVPSTAIREISLLK
Sbjct: 4 ELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLK 63
Query: 61 ELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
ELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYME IPKDQPLG +I+KKFMMQLCKG
Sbjct: 64 ELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKG 123
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
IAYCH+HRI+HRDLKPQNLLIN+DGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL
Sbjct: 124 IAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 183
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
LGGKQYSTGVD WSIGCIFAEMCNRKP+FSGDSEIDQIFKIFRVLGTPNE WPDI+YLP
Sbjct: 184 LGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLP 243
Query: 241 DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
DFK +FP+W R++LS+V+PSLD GIDLLDKL+ YDPI+RISA+RA HPYF+E
Sbjct: 244 DFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQE 297
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 390 bits (1002), Expect = e-108
Identities = 191/299 (63%), Positives = 239/299 (79%), Gaps = 12/299 (4%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQ--NRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
+ NY+++EK+GEGTYGVVYKA RH+ R+VAMKKIRLE E EGVPSTAIREISLLKE
Sbjct: 1 MENYQKVEKIGEGTYGVVYKA---RHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKE 57
Query: 62 LKDDN----IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKD--QPLGGNIIKKFMM 115
+ D+N VRL DI+H+++ KLYLVFEFLD+DLK+YM+ I + L +++KF
Sbjct: 58 VNDENNRSNCVRLLDILHAES-KLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTY 116
Query: 116 QLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYR 175
QL G+ +CH+ RIIHRDLKPQNLLI+++GNLKL DFGLAR+FGVPLR YTHEIVTLWYR
Sbjct: 117 QLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYR 176
Query: 176 APEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPD 235
APEVLLG + YSTGVD+WS+GCIFAEM R PLF GDSEID+IFKIF+VLGTPNE WP
Sbjct: 177 APEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPG 236
Query: 236 IIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ L D+K+TFP+W R +L +V+P+ + + I+LL ++ YDP HRISAKRA+Q Y ++
Sbjct: 237 VTLLQDYKSTFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQQNYLRD 295
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 389 bits (999), Expect = e-108
Identities = 187/286 (65%), Positives = 234/286 (81%), Gaps = 3/286 (1%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++++EK+GEGTYGVVYKA + R ++VA+KKIRL+ E EGVPSTAIREISLLKELK N
Sbjct: 4 FQKVEKIGEGTYGVVYKAKN-RETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPN 62
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHA 126
IVRL D+VH++ KLYLVFEFL DLK+YM+S P + L ++IK ++ QL +G+++CH+
Sbjct: 63 IVRLLDVVHNE-RKLYLVFEFLSQDLKKYMDSTPGSE-LPLHLIKSYLFQLLQGVSFCHS 120
Query: 127 HRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQY 186
HR+IHRDLKPQNLLIN G +KL DFGLARAFGVPLR YTHE+VTLWYRAPE+LLG K Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 187 STGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTTF 246
+T VD+WSIGCIFAEM RK LF GDSEIDQ+F+IFR+LGTP+E TWP + LPD+K +F
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
Query: 247 PKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
PKW R+ L E++P+L+ G DLL +L+ YDP RI+AK A+ HPYF
Sbjct: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 379 bits (974), Expect = e-105
Identities = 177/293 (60%), Positives = 231/293 (78%), Gaps = 6/293 (2%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQN--RVVAMKKIRLESEDEGVPSTAIREISLLKE 61
+ +Y ++EK+GEGTYGVVYK RH+ +VVAMKKIRLESE+EGVPSTAIREISLLKE
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKG---RHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKE 57
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L+ NIV L D++ D+ +LYL+FEFL +DLK+Y++SIP Q + +++K ++ Q+ +GI
Sbjct: 58 LRHPNIVSLQDVLMQDS-RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGI 116
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
+CH+ R++HRDLKPQNLLI+ G +KL DFGLARAFG+P+R YTHE+VTLWYR+PEVLL
Sbjct: 117 VFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLL 176
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
G +YST VD+WSIG IFAE+ +KPLF GDSEIDQ+F+IFR LGTPN WP++ L D
Sbjct: 177 GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD 236
Query: 242 FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+K TFPKW +L+ + +LD NG+DLL K++ YDP RIS K A+ HPYF +
Sbjct: 237 YKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 379 bits (972), Expect = e-105
Identities = 180/292 (61%), Positives = 235/292 (79%), Gaps = 4/292 (1%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y+++EK+GEGTYGVVYKA D + N +A+KKIRLE EDEGVPSTAIREISLLKE++
Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARD-KVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQ 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
NIV+ D+VHS+ +LYLVFE+LDLDLK++M+S P D ++IK ++ Q+ +GIAY
Sbjct: 60 HSNIVKYDDVVHSEK-RLYLVFEYLDLDLKKHMDSTP-DFSKDLHMIKTYLYQILRGIAY 117
Query: 124 CHAHRIIHRDLKPQNLLINRDGN-LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
CH+HR++HRDLKPQNLLI+R N LKL DFGLARAFG+P+R +THE+VTLWYRAPE+LLG
Sbjct: 118 CHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLG 177
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
YST VD+WS+GCIFAEM ++KPLF GDSEIDQ+FKIFR++GTP E TW + LPD+
Sbjct: 178 SHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDY 237
Query: 243 KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
K+ FPKW +L +P+LD +G+DLL K++ DP RI+A+ A++H YFK+
Sbjct: 238 KSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEYFKD 289
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 377 bits (969), Expect = e-105
Identities = 172/289 (59%), Positives = 231/289 (79%), Gaps = 2/289 (0%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ +++++EK+GEGTYGVVYK + R ++VAMKKIRLES+DEGVPSTAIREISLLKELK
Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRN-RLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELK 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
+NIV L D++ + +++YL+FEFL +DLK+YM+S+P D+ + +++ ++ Q+ I +
Sbjct: 60 HENIVCLEDVLMEE-NRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILF 118
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH R++HRDLKPQNLLI++ G +K+ DFGL R+FG+P+R YTHEIVTLWYRAPEVLLG
Sbjct: 119 CHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGS 178
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
+YS VD+WSIGCIFAEM RKPLF GDSEIDQ+F++FR+L TP E WP + LPD+K
Sbjct: 179 PRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYK 238
Query: 244 TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
TFP W+ L+ + +LDANGIDL+ K++ YDP+HRISAK ++HPYF
Sbjct: 239 NTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 373 bits (957), Expect = e-103
Identities = 179/292 (61%), Positives = 235/292 (80%), Gaps = 5/292 (1%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ N++++EK+GEGTYGVVYKA + + VVA+KKIRL++E EGVPSTAIREISLLKEL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYME-SIPKDQPLGGNIIKKFMMQLCKGIA 122
NIV+L D++H++ +KLYLVFEFL DLK++M+ S PL +IK ++ QL +G+A
Sbjct: 60 HPNIVKLLDVIHTE-NKLYLVFEFLHQDLKKFMDASALTGIPLP--LIKSYLFQLLQGLA 116
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
+CH+HR++HRDLKPQNLLIN +G +KL DFGLARAFGVP+R YTHE+VTLWYRAPE+LLG
Sbjct: 117 FCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLG 176
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
K YST VD+WS+GCIFAEM R+ LF GDSEIDQ+F+IFR LGTP+E WP + +PD+
Sbjct: 177 CKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY 236
Query: 243 KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
K +FPKW R++ S+V+P LD +G LL +++ YDP RISAK A+ HP+F++
Sbjct: 237 KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 350 bits (897), Expect = 2e-96
Identities = 168/296 (56%), Positives = 219/296 (73%), Gaps = 9/296 (3%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L ++ +LEK+GEGTYGVVYK + R N +VAMKKIRLESEDEGVPSTA+REISLLKEL+
Sbjct: 19 LNDFTKLEKIGEGTYGVVYKGKN-RRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQ 77
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
N+V L ++ + ++L+L+FEFL DLKRYM+ + KD+ L +K + Q+ + + +
Sbjct: 78 HPNVVGLEAVIMQE-NRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCF 136
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH R+IHRDLKPQNLL++ +G +KL DFGLARA G+P+R YTHE+VTLWYRAPE+L+G
Sbjct: 137 CHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGA 196
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
++YS GVD+WSIGCIFAEM +KPLF GDSEID++F+IFRVLGTP E W + LPD+K
Sbjct: 197 QRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYK 256
Query: 244 TTFPKWNRRNLSEVIPS-------LDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
TFPKW L + LD LL+ L+ YDP R++AK+A+ HPYF
Sbjct: 257 ATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF 312
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 340 bits (873), Expect = 1e-93
Identities = 166/290 (57%), Positives = 217/290 (74%), Gaps = 6/290 (2%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L N++R EK+GEGTYG+VYKA + VA+KKIRLE E EGVPSTAIREISLLK LK
Sbjct: 5 LDNFQRAEKIGEGTYGIVYKARS-NSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLK 63
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
N+V+L+D+V S + LY++FE+L++DLK+ M+ K +IK +M Q+ + +
Sbjct: 64 HPNVVQLFDVVIS-GNNLYMIFEYLNMDLKKLMDK--KKDVFTPQLIKSYMHQILDAVGF 120
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH +RI+HRDLKPQNLL++ G +KL DFGLARAF VP+RAYTHE+VTLWYRAPE+LLG
Sbjct: 121 CHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGT 180
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
K YSTGVD+WS+GCIF+EM R+ LF GDSEIDQ+++IFR L TP+E WP + LPDFK
Sbjct: 181 KFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFK 240
Query: 244 TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
T FP+W N+ + I +A+ +L+ ++ YDP RISAK A+QH YF+
Sbjct: 241 TKFPRWEGTNMPQPITEHEAH--ELIMSMLCYDPNLRISAKDALQHAYFR 288
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 333 bits (853), Expect = 2e-91
Identities = 164/293 (55%), Positives = 218/293 (73%), Gaps = 7/293 (2%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y++LEK+GEGTYG V+KA + R + +VA+K++RL+ +DEGVPS+A+REI LLKELK
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKN-RETHEIVALKRVRLDDDDEGVPSSALREICLLKELK 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
NIVRL+D++HSD KL LVFEF D DLK+Y +S D L I+K F+ QL KG+ +
Sbjct: 60 HKNIVRLHDVLHSDK-KLTLVFEFCDQDLKKYFDSCNGD--LDPEIVKSFLFQLLKGLGF 116
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH+ ++HRDLKPQNLLINR+G LKL DFGLARAFG+P+R Y+ E+VTLWYR P+VL G
Sbjct: 117 CHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGA 176
Query: 184 KQYSTGVDVWSIGCIFAEMCNR-KPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
K YST +D+WS GCIFAE+ N +PLF G+ DQ+ +IFR+LGTP E WP + LPD+
Sbjct: 177 KLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDY 236
Query: 243 KTTFPKW-NRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
K +P + +L V+P L+A G DLL L+ +P+ RISA+ A+QHPYF +
Sbjct: 237 K-PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 330 bits (846), Expect = 1e-90
Identities = 166/305 (54%), Positives = 221/305 (72%), Gaps = 18/305 (5%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y++LEKVGEGTYG VYKA++ + ++VA+KK RLE ++EG+P TA+REISLL+ L
Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAME-KTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 64 DD-NIVRLY-----------DIVHSDAHKLYLVFEFLDLDLKRYMESIPKD---QPLGGN 108
IVRL + HS LYLVFE+LD DLK++++S K +PL +
Sbjct: 60 QSIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEAS 119
Query: 109 IIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAFGVPLRAYTH 167
++++FM QL KG+A+CH+H ++HRDLKPQNLL+++D G LK+ D GL+RAF VPL+AYTH
Sbjct: 120 LVQRFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTH 179
Query: 168 EIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGT 227
EIVTLWYRAPEVLLG YST VD+WS+GCIFAEM R+ LF GDSE Q+ IFR+LGT
Sbjct: 180 EIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGT 239
Query: 228 PNERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
P E+ WP ++ L D+ +PKW ++LS +PSL GIDLL +++ Y+P RISAK A+
Sbjct: 240 PTEQQWPGVMALRDWH-VYPKWEPQDLSRAVPSLSPEGIDLLTQMLKYNPAERISAKAAL 298
Query: 288 QHPYF 292
HPYF
Sbjct: 299 DHPYF 303
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 327 bits (838), Expect = 1e-89
Identities = 165/303 (54%), Positives = 217/303 (71%), Gaps = 16/303 (5%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y++LEKVGEGTYG VYKA++ + ++VA+KK RLE ++EG+P TA+REISLL+ L
Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAME-KGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 64 DD-NIVRLYDIVH---------SDAHKLYLVFEFLDLDLKRYMESI---PKDQPLGGNII 110
+VRL + H S LYLVFE+LD DLK++++S P +PL +I
Sbjct: 60 TSIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLI 119
Query: 111 KKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNL-KLGDFGLARAFGVPLRAYTHEI 169
+K M QLCKG+A+CH+H ++HRDLKPQNLL+ +D L K+ D GL RAF VPL++YTHEI
Sbjct: 120 QKLMFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTVPLKSYTHEI 179
Query: 170 VTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPN 229
VTLWYRAPEVLLG YSTGVD+WS+GCIFAEM R+ LF GDSE Q+ IFR+LGTP
Sbjct: 180 VTLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPT 239
Query: 230 ERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQH 289
E+ WP + L D+ +PKW ++L+ +PSL G+DLL K++ Y+P RISAK A+ H
Sbjct: 240 EQQWPGVSTLRDWH-VYPKWEPQDLTLAVPSLSPQGVDLLTKMLKYNPAERISAKTALDH 298
Query: 290 PYF 292
PYF
Sbjct: 299 PYF 301
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 317 bits (811), Expect = 2e-86
Identities = 155/301 (51%), Positives = 219/301 (72%), Gaps = 9/301 (2%)
Query: 1 MSELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLK 60
+S + +++LEKVGEGTYG VY+A + + +VA+KK RL ++EGVP T +REIS+L+
Sbjct: 10 VSAMEAFEKLEKVGEGTYGKVYRARE-KATGMIVALKKTRLHEDEEGVPPTTLREISILR 68
Query: 61 EL-KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFM 114
L +D +IVRL D+ + LYLVFE++D DLK+++ S + Q + N +K M
Sbjct: 69 MLARDPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLM 128
Query: 115 MQLCKGIAYCHAHRIIHRDLKPQNLLINRDG-NLKLGDFGLARAFGVPLRAYTHEIVTLW 173
QLCKG+A+CH H ++HRDLKP NLL++R LK+ D GLARAF +P++ YTHEI+TLW
Sbjct: 129 YQLCKGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTLPMKKYTHEILTLW 188
Query: 174 YRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
YRAPEVLLG YSTGVD+WS+GCIFAE+ ++ +F+GDSE+ Q+ +IFR+LGTPNE W
Sbjct: 189 YRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVW 248
Query: 234 PDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
P + L D+ +P+W +LS +P+LD G+DLL K++ Y+P RISAK+A++HPYF
Sbjct: 249 PGVSKLKDWH-EYPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYFD 307
Query: 294 E 294
+
Sbjct: 308 D 308
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 317 bits (811), Expect = 2e-86
Identities = 155/294 (52%), Positives = 216/294 (72%), Gaps = 9/294 (3%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y ++EK+GEGTYG V+K + R +VA+K++RL+ +DEGVPS+A+REI LLKELK
Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRN-RDTMEIVALKRVRLDEDDEGVPSSALREICLLKELK 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
NIVRL D++HSD KL LVFE D DLK+Y +S+ + + + + FM+QL +G+A+
Sbjct: 60 HKNIVRLIDVLHSDK-KLTLVFEHCDQDLKKYFDSLNGEIDMA--VCRSFMLQLLRGLAF 116
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH+H ++HRDLKPQNLLIN++G LKL DFGLARAFG+P++ Y+ E+VTLWYR P+VL G
Sbjct: 117 CHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGA 176
Query: 184 KQYSTGVDVWSIGCIFAEMCNR-KPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
K Y+T +D+WS GCI AE+ + +PLF G +DQ+ KIFRVLGTPNE +WP + +L D+
Sbjct: 177 KLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDY 236
Query: 243 KT--TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+FP + S+++P L++ G DLL KL+ P RISA+ A+QHPYF +
Sbjct: 237 VALPSFPAIT--SWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 310 bits (795), Expect = 1e-84
Identities = 148/287 (51%), Positives = 212/287 (73%), Gaps = 3/287 (1%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
NY+RLEK+GEGTY VYK + R +VA+K IR+++ DEG PSTAIREISL+KEL+
Sbjct: 2 NYQRLEKLGEGTYAHVYKGQN-RVTGEIVALKVIRIDA-DEGTPSTAIREISLMKELRHP 59
Query: 66 NIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
NI+ L D++ ++ +KL LVFE+++ DLK+YM++ L + +K F QL KGI++CH
Sbjct: 60 NIMSLSDVLQTE-NKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCH 118
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+R++HRDLKPQNLLIN G LKL DFGLAR+ G+P+ +++E+VTLWYRAP+VLLG +
Sbjct: 119 ENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRV 178
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTT 245
YST +D+WS+GCI AEM +PLF+G + DQ+ KIFR+LGTP E++WP I LP++K T
Sbjct: 179 YSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKPT 238
Query: 246 FPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
FP + ++L+ + P+ D G+DLL +++ P R + + A+QH +F
Sbjct: 239 FPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAWF 285
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 309 bits (792), Expect = 3e-84
Identities = 149/293 (50%), Positives = 217/293 (73%), Gaps = 7/293 (2%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ NY ++EK+GEGTYG V+KA + ++ +VA+K++RL+ +DEGVPS+A+REI +L+ELK
Sbjct: 1 MLNYDKMEKIGEGTYGTVFKARN-KNSGEIVALKRVRLDDDDEGVPSSALREICILRELK 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
N+VRLYD+VHS+ +KL LVFE+ D DLK++ +S+ + + + M+QL +G+++
Sbjct: 60 HRNVVRLYDVVHSE-NKLTLVFEYCDQDLKKFFDSL--NGYMDAQTARSLMLQLLRGLSF 116
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CHAH ++HRDLKPQNLLIN +G LKL DFGLARAFGVP+R ++ E+VTLWYR P+VL G
Sbjct: 117 CHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGA 176
Query: 184 KQYSTGVDVWSIGCIFAEMCNR-KPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
K Y+T +D+WS GCIFAE+ N +PLF G DQ+ +IF+ LG+P+E WP I LPD+
Sbjct: 177 KLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDY 236
Query: 243 KTTFPKWN-RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
K +P ++ S+++P+L++ G DLL KL+ +P RI A A++H YF +
Sbjct: 237 K-PYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFAD 288
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 308 bits (789), Expect = 6e-84
Identities = 155/302 (51%), Positives = 215/302 (70%), Gaps = 11/302 (3%)
Query: 1 MSELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLK 60
MS + +K+LEK+G GTY VYK ++ + VA+K+++L+SE EG PSTAIREISL+K
Sbjct: 1 MSSSSQFKQLEKLGNGTYATVYKGLN-KTTGVYVALKEVKLDSE-EGTPSTAIREISLMK 58
Query: 61 ELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGG---NIIKKFMMQL 117
ELK +NIVRLYD++H++ +KL LVFEF+D DLK+YM+S G N++K F QL
Sbjct: 59 ELKHENIVRLYDVIHTE-NKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQL 117
Query: 118 CKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP 177
+G+A+CH ++I+HRDLKPQNLLIN+ G LKLGDFGLARAFG+P+ ++ E+VTLWYRAP
Sbjct: 118 LQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 177
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
+VL+G + YST +D+WS GCI AEM KPLF G ++ +Q+ IF ++GTPNE WP +
Sbjct: 178 DVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVT 237
Query: 238 YLPDFKTTFPKWNRRNLSEVI-----PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
LP + + R+L +V+ LD N +D L L+ +P R+SAK+A+ HP+F
Sbjct: 238 KLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF 297
Query: 293 KE 294
E
Sbjct: 298 AE 299
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 307 bits (786), Expect = 1e-83
Identities = 148/289 (51%), Positives = 207/289 (71%), Gaps = 4/289 (1%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++++LEK+GEGTYGVVYKA + R+ NRVVA+KKIRLE+E+EG+P+T IREI LLK LK
Sbjct: 4 SFQKLEKIGEGTYGVVYKARE-RNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHS 62
Query: 66 NIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPL-GGNIIKKFMMQLCKGIAYC 124
IV L D+++++ +K+YLVFE+++LDL+RY++ + + L ++K QL + YC
Sbjct: 63 TIVELSDVIYNN-NKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAMEYC 121
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H+ I HRDLKPQN+L++ N+KL DFGL RA G+PLR YT E+VTLWYR PE+LLG K
Sbjct: 122 HSRNIFHRDLKPQNILVDPKENIKLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGCK 181
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKT 244
Y VDVWS CI AE+ +P F GDSEIDQ+F+IF+VLGTPN W ++ P++K
Sbjct: 182 YYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVENFPNYKV 241
Query: 245 TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
FP W+ +L + D + +DL+ K++ YDP R++AK + H YF+
Sbjct: 242 EFPVWDPVDLKTIFRG-DPDFVDLISKMLEYDPKMRMTAKNGLSHKYFE 289
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 306 bits (785), Expect = 2e-83
Identities = 152/304 (50%), Positives = 215/304 (70%), Gaps = 15/304 (4%)
Query: 1 MSELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLK 60
+S + +++LEKVGEGTYG VY+A + + ++VA+KK RL ++EGVPST +REIS+L+
Sbjct: 8 VSAMDAFEKLEKVGEGTYGKVYRARE-KATGKIVALKKTRLHEDEEGVPSTTLREISILR 66
Query: 61 EL-KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNI----IK 111
L +D ++VRL D+ + + LYLVFE++D D+K+++ S + G NI IK
Sbjct: 67 MLARDPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSF---RSTGKNIPTQTIK 123
Query: 112 KFMMQLCKGIAYCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYTHEIV 170
M QLCKG+A+CH H I+HRDLKP NLL++ + LK+ D GLARAF +P++ YTHEI+
Sbjct: 124 SLMYQLCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTLPMKKYTHEIL 183
Query: 171 TLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNE 230
TLWYRAPEVLLG YST VD+WS+GCIFAE+ + +F GDSE+ Q+ IF++ GTPNE
Sbjct: 184 TLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNE 243
Query: 231 RTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHP 290
WP + L ++ +P+W LS +P+LD G+DLL K++ Y+P RISAK A++HP
Sbjct: 244 EMWPGVSTLKNWH-EYPQWKPSTLSSAVPNLDEAGVDLLSKMLQYEPAKRISAKMAMEHP 302
Query: 291 YFKE 294
YF +
Sbjct: 303 YFDD 306
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 305 bits (780), Expect = 7e-83
Identities = 147/301 (48%), Positives = 206/301 (67%), Gaps = 20/301 (6%)
Query: 10 LEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 69
L ++GEGTYGVV+KA+ +R N A+K IR + ++EG+PST +REIS +K+L+ DNIV
Sbjct: 48 LRRIGEGTYGVVFKAIHVR-DNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVT 106
Query: 70 LYDIVH---------------SDAHKLYLVFEFLDLDLKRYMESI-PKDQPLGGNIIKKF 113
L+DI++ S KLY+VFEF+D DLK +E + P + L N +K F
Sbjct: 107 LFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSF 166
Query: 114 MMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLW 173
M QL ++YCH RI+HRDLKPQN+L++ G +K+ DFGLAR F P R YTHE+VTLW
Sbjct: 167 MWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFSFPSRNYTHEVVTLW 226
Query: 174 YRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
YR PE+LLG ++YST +D+WS+GCIF+E+ + KPLF G+ EI Q+FKIF ++GTPN ++W
Sbjct: 227 YRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIKSW 286
Query: 234 PDIIYLPDFKTTFPKW--NRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
P + P +K FP+W N + L E L NG+D+L +++ Y P R++AK A+ H Y
Sbjct: 287 PGVDSFPHYKAVFPQWPVNLKKLEET-SCLTGNGLDVLREILRYPPERRLTAKGALSHRY 345
Query: 292 F 292
F
Sbjct: 346 F 346
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 297 bits (760), Expect = 1e-80
Identities = 152/292 (52%), Positives = 205/292 (70%), Gaps = 39/292 (13%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ N++++EK+GEGTYGVVYKA + + VVA+KKIRL++E EGVPSTAIREISLLKEL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYME-SIPKDQPLGGNIIKKFMMQLCKGIA 122
NIV+L D++H++ +KLYLVFEFL DLK++M+ S PL +IK ++ QL +G+A
Sbjct: 60 HPNIVKLLDVIHTE-NKLYLVFEFLHQDLKKFMDASALTGIPLP--LIKSYLFQLLQGLA 116
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
+CH+HR++HRDLKPQNLLIN +G +KL DFGLARAFGVP+R YTHE+
Sbjct: 117 FCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEV------------- 163
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
R+ LF GDSEIDQ+F+IFR LGTP+E WP + +PD+
Sbjct: 164 ---------------------TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY 202
Query: 243 KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
K +FPKW R++ S+V+P LD +G LL +++ YDP RISAK A+ HP+F++
Sbjct: 203 KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPYKRISAKAALAHPFFQD 254
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 296 bits (758), Expect = 2e-80
Identities = 153/296 (51%), Positives = 205/296 (68%), Gaps = 16/296 (5%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+L Y +L+K+GEGTY VYK N +VA+K+IRLE E EG P TAIRE+SLLK+L
Sbjct: 161 KLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLEHE-EGAPCTAIREVSLLKDL 218
Query: 63 KDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNII-----KKFMMQL 117
K NIV L+DI+H++ L LVFE+LD DLK+Y++ GNII K F+ QL
Sbjct: 219 KHANIVTLHDIIHTEK-SLTLVFEYLDKDLKQYLDDC-------GNIINMHNVKLFLFQL 270
Query: 118 CKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP 177
+G+AYCH +++HRDLKPQNLLIN G LKL DFGLARA +P + Y++E+VTLWYR P
Sbjct: 271 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP 330
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
++LLG YST +D+W +GCIF EM +PLF G + +Q+ IFR+LGTP E TWP I+
Sbjct: 331 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL 390
Query: 238 YLPDFKT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+FKT +PK+ L P LD++G DLL KL+ ++ +RISA+ A++HP+F
Sbjct: 391 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 296 bits (758), Expect = 2e-80
Identities = 153/296 (51%), Positives = 205/296 (68%), Gaps = 16/296 (5%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+L Y +L+K+GEGTY VYK N +VA+K+IRLE E EG P TAIRE+SLLK+L
Sbjct: 113 KLETYIKLDKLGEGTYATVYKGKSKLTDN-LVALKEIRLEHE-EGAPCTAIREVSLLKDL 170
Query: 63 KDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNII-----KKFMMQL 117
K NIV L+DI+H++ L LVFE+LD DLK+Y++ GNII K F+ QL
Sbjct: 171 KHANIVTLHDIIHTEK-SLTLVFEYLDKDLKQYLDDC-------GNIINMHNVKLFLFQL 222
Query: 118 CKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP 177
+G+AYCH +++HRDLKPQNLLIN G LKL DFGLARA +P + Y++E+VTLWYR P
Sbjct: 223 LRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPP 282
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
++LLG YST +D+W +GCIF EM +PLF G + +Q+ IFR+LGTP E TWP I+
Sbjct: 283 DILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGIL 342
Query: 238 YLPDFKT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+FKT +PK+ L P LD++G DLL KL+ ++ +RISA+ A++HP+F
Sbjct: 343 SNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 398
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 293 bits (750), Expect = 2e-79
Identities = 152/297 (51%), Positives = 204/297 (68%), Gaps = 16/297 (5%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
++ Y +LEK+GEGTY VYK +N +VA+K+IRLE E EG P TAIRE+SLLK+L
Sbjct: 188 KMETYIKLEKLGEGTYATVYKGRSKLTEN-LVALKEIRLEHE-EGAPCTAIREVSLLKDL 245
Query: 63 KDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNI-----IKKFMMQL 117
K NIV L+DIVH+D L LVFE+LD DLK+YM+ GNI +K F+ Q+
Sbjct: 246 KHANIVTLHDIVHTDK-SLTLVFEYLDKDLKQYMDDC-------GNIMSMHNVKLFLYQI 297
Query: 118 CKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP 177
+G+AYCH +++HRDLKPQNLLIN G LKL DFGLARA VP + Y++E+VTLWYR P
Sbjct: 298 LRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPP 357
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
+VLLG +Y T +D+W +GCIF EM + +PLF G + D++ IFR+LGTP++ TWP I
Sbjct: 358 DVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGIS 417
Query: 238 YLPDFKT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+FK FPK+ L P LD+ GI+L+ K + Y+ R+SA+ A++H YF+
Sbjct: 418 SNEEFKNYNFPKYKPEPLINHAPRLDSEGIELIRKFLQYESKKRVSAEEAMKHVYFR 474
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 285 bits (728), Expect = 7e-77
Identities = 147/292 (50%), Positives = 199/292 (67%), Gaps = 6/292 (2%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+L Y +L+K+GEGTY V+K +N +VA+K+IRLE E EG P TAIRE+SLLK L
Sbjct: 138 KLETYVKLDKLGEGTYATVFKGRSKLTEN-LVALKEIRLEHE-EGAPCTAIREVSLLKNL 195
Query: 63 KDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
K NIV L+D++H+D L LVFE+LD DLK+Y++ + +K FM QL +G+A
Sbjct: 196 KHANIVTLHDLIHTD-RSLTLVFEYLDSDLKQYLDHCGNLMSMHN--VKIFMFQLLRGLA 252
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
YCH +I+HRDLKPQNLLIN G LKL DFGLARA VP + Y++E+VTLWYR P+VLLG
Sbjct: 253 YCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLG 312
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
+YST +D+W +GCI EM +PLF G + +++ IFR+LGTP E TWP + +F
Sbjct: 313 STEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEF 372
Query: 243 KT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+T +FP + + L P LD +GI LL L+ Y+ R+SA+ A+ H YF+
Sbjct: 373 RTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFR 424
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 273 bits (699), Expect = 2e-73
Identities = 138/297 (46%), Positives = 196/297 (65%), Gaps = 12/297 (4%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++RL K+ EGTYGVVY+A D + +VA+KK+++E E EG P T++REI++L +
Sbjct: 406 FERLNKIDEGTYGVVYRAKD-KKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPS 464
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + ++V S +++V E+++ DLK ME++ Q + +K M+QL +G+ Y H
Sbjct: 465 IVDVKEVVVGSSLDSIFMVMEYMEHDLKALMETMK--QRFSQSEVKCLMLQLLEGVKYLH 522
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ ++HRDLK NLL+N G LK+ DFGLAR +G PL+ YTH +VTLWYRAPE+LLG KQ
Sbjct: 523 DNWVLHRDLKTSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQ 582
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTT 245
YST +D+WS+GCI AE+ + PLF+G +E DQ+ KIFR+LGTPNE WP LP K
Sbjct: 583 YSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVKVN 642
Query: 246 FPKWNRRNLSEVIPS--------LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
F K L + P+ L G DLL+KL+TYDP RI+ A++H +F+E
Sbjct: 643 FVKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFRE 699
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 267 bits (683), Expect = 1e-71
Identities = 142/295 (48%), Positives = 194/295 (65%), Gaps = 12/295 (4%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+L Y++L+K+GEGTY V++ + N+ VA+K+IRLE E EG P TAIRE+SLL+ L
Sbjct: 357 KLETYEKLDKLGEGTYATVFRGRSIL-TNKFVALKEIRLEQE-EGAPCTAIREVSLLRNL 414
Query: 63 KDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
+ N+V L+DI+H+D L LVFE++D DLK+YM+S + N I+ F+ QL +G+A
Sbjct: 415 RHANVVTLHDIIHTD-RLLTLVFEYVDRDLKQYMDSCNNAMQM--NNIRLFLYQLLRGLA 471
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
YCH R++HRDLKPQNLLI G LKL DFGLARA VP + Y++E+VTLWYR P+VLLG
Sbjct: 472 YCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLG 531
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
YST +D+W +GCI EM + LF G + +Q+ IFR LG+P P I P F
Sbjct: 532 STDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTF 591
Query: 243 KTTFPKWNRR----NLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+P NR L IP +DA+G +LL K + Y+ R+SA AV+HP+ +
Sbjct: 592 ---YPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFLR 643
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 267 bits (683), Expect = 1e-71
Identities = 142/295 (48%), Positives = 194/295 (65%), Gaps = 12/295 (4%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+L Y++L+K+GEGTY V++ + N+ VA+K+IRLE E EG P TAIRE+SLL+ L
Sbjct: 234 KLETYEKLDKLGEGTYATVFRGRSIL-TNKFVALKEIRLEQE-EGAPCTAIREVSLLRNL 291
Query: 63 KDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
+ N+V L+DI+H+D L LVFE++D DLK+YM+S + N I+ F+ QL +G+A
Sbjct: 292 RHANVVTLHDIIHTD-RLLTLVFEYVDRDLKQYMDSCNNAMQM--NNIRLFLYQLLRGLA 348
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
YCH R++HRDLKPQNLLI G LKL DFGLARA VP + Y++E+VTLWYR P+VLLG
Sbjct: 349 YCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLG 408
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
YST +D+W +GCI EM + LF G + +Q+ IFR LG+P P I P F
Sbjct: 409 STDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTF 468
Query: 243 KTTFPKWNRR----NLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+P NR L IP +DA+G +LL K + Y+ R+SA AV+HP+ +
Sbjct: 469 ---YPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFLR 520
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 266 bits (680), Expect = 3e-71
Identities = 134/286 (46%), Positives = 186/286 (64%), Gaps = 5/286 (1%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y + E +G+GTYGVV+KA D ++ VA+KKIRL E EGV TA+REI LLKELK +
Sbjct: 11 YLKREVLGQGTYGVVFKATDTKN-GETVAIKKIRLGKEKEGVNVTALREIKLLKELKHPH 69
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHA 126
I+ L D L++VFEF++ DL+ + ++ L +K ++ + KG+ YCH
Sbjct: 70 IIELID-AFPHKENLHIVFEFMETDLEAVIRD--RNLYLSPGDVKSYLQMILKGLEYCHG 126
Query: 127 HRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQY 186
++HRD+KP NLLI +G LKL DFGLAR FG P R +TH++ WYRAPE+L G KQY
Sbjct: 127 KWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFGAKQY 186
Query: 187 STGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTTF 246
VDVW+ GCIFAE+ R+P G+S+IDQ+ KIF GTP WPD+I LPD+ +
Sbjct: 187 DGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDY-VEY 245
Query: 247 PKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+L ++P++ + +DLL K+ TYDP RIS ++A++H YF
Sbjct: 246 QFVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQQALKHRYF 291
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 82 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 140
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 141 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 198
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 199 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 258
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 259 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 318
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 319 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 369
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 414 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 472
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 473 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 530
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 531 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 590
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 591 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 650
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 651 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 701
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 423 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 481
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 482 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 539
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 599
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 600 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 659
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 104 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 162
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 163 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 220
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 221 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 280
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 281 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 340
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 341 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 391
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 208 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 266
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 267 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 324
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 325 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 384
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 385 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 444
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 445 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 495
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 391 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 449
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 450 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 507
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 508 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 567
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 568 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 627
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 628 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 678
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 380 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 438
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 439 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 496
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 497 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 556
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 557 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 616
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 617 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 667
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 169 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 227
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 228 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 285
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 286 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 345
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 346 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 405
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 406 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 456
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 425 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 483
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 484 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 541
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 542 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 601
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 602 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 661
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 662 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 712
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 265 bits (678), Expect = 4e-71
Identities = 138/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 438 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 496
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 497 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 554
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VTLWYRAPE+LLG K+
Sbjct: 555 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 614
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 615 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 674
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 675 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 725
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 265 bits (677), Expect = 6e-71
Identities = 137/291 (47%), Positives = 201/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E+EG P T++REI+ + + + N
Sbjct: 418 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPN 476
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 477 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 534
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VT WYRAPE+LLG K+
Sbjct: 535 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 594
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G+SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 595 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 654
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 655 TFSEHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 705
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 265 bits (677), Expect = 6e-71
Identities = 137/291 (47%), Positives = 201/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E+EG P T++REI+ + + + N
Sbjct: 420 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPN 478
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 479 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 536
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VT WYRAPE+LLG K+
Sbjct: 537 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 596
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G+SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 597 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 656
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 657 TFSEHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 707
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 265 bits (677), Expect = 6e-71
Identities = 140/288 (48%), Positives = 184/288 (63%), Gaps = 9/288 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y R + +GEGTYGVVYKA D + + VA+KKIRL ++ EGV TA+REI LLKEL +
Sbjct: 13 YLRRQILGEGTYGVVYKATDTK-TGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPH 71
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQP--LGGNIIKKFMMQLCKGIAYC 124
IV L D D L+LVFE++ DL E++ +D+ L IK +M+ KG+AYC
Sbjct: 72 IVELIDAFPHDG-SLHLVFEYMQTDL----EAVIRDRNIFLSPGDIKSYMLMTLKGLAYC 126
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H ++HRD+KP NLLI +G LKL DFGLAR FG P R +TH++ WYRAPE+L G +
Sbjct: 127 HKKWVLHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSR 186
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKT 244
QY GVDVW+ GCIFAE+ R+P G +EIDQ+ KIF+ GTP W D+IYLPD+
Sbjct: 187 QYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDY-M 245
Query: 245 TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
F L + P + +DLL K+ YDP RI+ ++A+ H YF
Sbjct: 246 EFSYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDHRYF 293
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 264 bits (675), Expect = 1e-70
Identities = 137/288 (47%), Positives = 187/288 (64%), Gaps = 9/288 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y + E +G+GTYGVV+KA D + + + VA+KKIRL + EGV TA+REI +LKELK +
Sbjct: 12 YLKQEVLGQGTYGVVFKATDTKTE-QTVAIKKIRLGKQREGVNITALREIKMLKELKHPH 70
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQP--LGGNIIKKFMMQLCKGIAYC 124
I+ L D L+LVFEF++ DL E++ +D L IK +++ KG+AYC
Sbjct: 71 IILLID-AFPHKENLHLVFEFMETDL----EAVIRDSNIFLSPADIKSYLLMTFKGLAYC 125
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H ++HRD+KP NLLI DG LKL DFGLAR FG P R +TH++ WYRAPE+L G K
Sbjct: 126 HDKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFGAK 185
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKT 244
QY VDVW++ CIFAE+ R+P G+S+IDQ+ KIF GTP WPD+ LPD+
Sbjct: 186 QYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDLTKLPDY-V 244
Query: 245 TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+ +L + P++ + +DLL K+ TYDP RIS K+A++H YF
Sbjct: 245 EYQFVPAPSLRSLFPAVSDDALDLLSKMFTYDPKARISIKQALEHRYF 292
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 264 bits (674), Expect = 1e-70
Identities = 137/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 420 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 478
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 479 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 536
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VT WYRAPE+LLG K+
Sbjct: 537 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 596
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G+SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 597 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 656
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 657 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 707
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 264 bits (674), Expect = 1e-70
Identities = 137/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 423 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 481
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 482 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 539
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VT WYRAPE+LLG K+
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G+SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 659
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 264 bits (674), Expect = 1e-70
Identities = 137/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 410 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 468
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 469 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 526
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VT WYRAPE+LLG K+
Sbjct: 527 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 586
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G+SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 587 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 646
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 647 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 697
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 264 bits (674), Expect = 1e-70
Identities = 137/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 419 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 477
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 478 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 535
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VT WYRAPE+LLG K+
Sbjct: 536 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 595
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G+SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 596 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 655
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 656 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 706
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 264 bits (674), Expect = 1e-70
Identities = 137/291 (47%), Positives = 200/291 (68%), Gaps = 6/291 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D + + +VA+K++++E E EG P T++REI+ + + + N
Sbjct: 40 FQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 98
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV + +IV S+ K+Y+V +++ DLK ME++ QP +K M+QL +G+ + H
Sbjct: 99 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLH 156
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDLK NLL++ G LK+GDFGLAR +G PL+AYT +VT WYRAPE+LLG K+
Sbjct: 157 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 216
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
YST VD+WS+GCIF E+ +KPLF G+SEIDQI K+F+ LGTP+E+ WP LP K
Sbjct: 217 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 276
Query: 245 TFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
TF + NL + + L G DL++K +TY P RISA+ ++H YF+E
Sbjct: 277 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 327
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 260 bits (665), Expect = 1e-69
Identities = 136/298 (45%), Positives = 189/298 (62%), Gaps = 10/298 (3%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
+ + +Y+ LEK+ EG+YG+VY+ +D + N +VA+KKI+ + G P T++REI L
Sbjct: 69 NSIDDYEILEKIEEGSYGIVYRGLD-KSTNTLVALKKIKFDPNGIGFPITSLREIESLSS 127
Query: 62 LKDDNIVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
++ DNIV L +V D +YLV EF++ DLK ++++P+D + +K M+QL
Sbjct: 128 IRHDNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPED--FLQSEVKTLMLQLLAA 185
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
A+ H H +HRDLKP NLL+N G +KL DFGLAR P + T +VTLWYRAPE+L
Sbjct: 186 TAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELL 245
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
LG Y +D+WSIGCIFAEM R PLFSG SE+DQ++KIF +LG P WP LP
Sbjct: 246 LGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLP 305
Query: 241 DFK----TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
T P ++ S IP+L N DLL++L++ +P RISAK A++HPYF E
Sbjct: 306 YANKIKHPTVPTHSKIRTS--IPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYE 361
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 258 bits (658), Expect = 9e-69
Identities = 140/292 (47%), Positives = 185/292 (62%), Gaps = 9/292 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y +LE +GEG+Y VYK RV A+K+IRL+ E+EG P TAIRE SLLKELK N
Sbjct: 192 YVKLEPLGEGSYATVYKGFSKLTYQRV-ALKEIRLQ-EEEGAPFTAIREASLLKELKHSN 249
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHA 126
IV L+DIVH+ L VFE+++ DL +YME P L ++ F+ QL +G++YCH
Sbjct: 250 IVTLHDIVHT-RETLTFVFEYVNTDLSQYMEKHPGG--LDHRNVRLFLFQLLRGLSYCHK 306
Query: 127 HRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQY 186
R++HRD+KPQNLLI+ G LKL DFGLARA VP Y+HE+VTLWYR P+VLLG +Y
Sbjct: 307 RRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEY 366
Query: 187 STGVDVWSIGCIFAEMCNRKPLFSGDSE-IDQIFKIFRVLGTPNERTWPDIIYLPDFKT- 244
ST +D+W +GCIF EM P F G + DQ+ KIF++LGTP E TWP + + P +K
Sbjct: 367 STSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPH 426
Query: 245 TFPKWNRRNLSEVIPSL--DANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ R L P L G + + + +P R+ A A+QHPYF +
Sbjct: 427 KLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQ 478
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 256 bits (655), Expect = 2e-68
Identities = 141/296 (47%), Positives = 192/296 (64%), Gaps = 21/296 (7%)
Query: 1 MSELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLK 60
+S K+LEK+GEGTYG V+KA + + +VA+K +RL+ D+GVPS+A+REI LLK
Sbjct: 69 LSREDEQKKLEKIGEGTYGTVFKAKNWE-THEIVALKWVRLDDNDDGVPSSALREICLLK 127
Query: 61 ELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
ELK NIVRL+D++HSD KL LVF+F LK+Y +S D L I+K F+ QL KG
Sbjct: 128 ELKHKNIVRLHDLLHSDK-KLTLVFKFCHQHLKKYFDSCNGD--LDPEIVKSFLFQLLKG 184
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
+ +CH+ ++ RDLKPQNLLINR+G LKL DFGL+RAFG+P+ Y V
Sbjct: 185 LGFCHSRNVLRRDLKPQNLLINRNGELKLADFGLSRAFGIPI-CY-------------VF 230
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
G K YST +D+WS GCIFAE+ N PLF G+ DQ+ +IF +LG + WP + L
Sbjct: 231 FGAKLYSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFWLLGMLTKEQWPSMTKL 290
Query: 240 PDFKTTFPKW-NRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
PD+K +P + +L ++P L A G DLL L+ +P ISA+ A+Q+PYF +
Sbjct: 291 PDYK-LYPLYPATTSLVNIVPKLSATGRDLLQNLLKCNPCQCISAEEALQYPYFSD 345
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 255 bits (651), Expect = 6e-68
Identities = 143/293 (48%), Positives = 192/293 (64%), Gaps = 9/293 (3%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y++LEK+GEG+Y VYK + ++VA+K IRL+ E+EG P TAIRE SLLK LK
Sbjct: 116 SYEKLEKLGEGSYATVYKGKS-KVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHA 173
Query: 66 NIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
NIV L+DI+H+ L LVFE++ DL +YM+ P L + +K F+ QL +G++Y H
Sbjct: 174 NIVLLHDIIHTK-ETLTLVFEYVHTDLCQYMDKHPGG--LHPDNVKLFLFQLLRGLSYIH 230
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
I+HRDLKPQNLLI+ G LKL DFGLARA VP Y++E+VTLWYR P+VLLG +
Sbjct: 231 QRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTE 290
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEI-DQIFKIFRVLGTPNERTWPDIIYLPDFK- 243
YST +D+W +GCIF EM F G +I DQ+ +IF VLGTPNE TWP + LP FK
Sbjct: 291 YSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKP 350
Query: 244 TTFPKWNRRNLSEVIPSLD--ANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
F ++ +NL + L + DL KL+ P +R+SA+ A+ H YF +
Sbjct: 351 ERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSD 403
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 255 bits (651), Expect = 6e-68
Identities = 132/295 (44%), Positives = 196/295 (65%), Gaps = 12/295 (4%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD-- 64
Y+ + ++GEG YG V+KA DL++ R VA+K++R+++ +EG+P + IRE+++L+ L+
Sbjct: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFE 72
Query: 65 -DNIVRLYDIV---HSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
N+VRL+D+ +D KL LVFE +D DL Y++ +P + + IK M QL +
Sbjct: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVP-EPGVPTETIKDMMFQLLR 131
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 179
G+ + H+HR++HRDLKPQN+L+ G +KL DFGLAR + + A T +VTLWYRAPEV
Sbjct: 132 GLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEV 190
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
LL Y+T VD+WS+GCIFAEM RKPLF G S++DQ+ KI V+G P E WP + L
Sbjct: 191 LLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVAL 249
Query: 240 PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P + F + + + + + +D G DLL K +T++P RISA A+ HPYF++
Sbjct: 250 P--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQD 302
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 251 bits (642), Expect = 7e-67
Identities = 134/296 (45%), Positives = 189/296 (63%), Gaps = 15/296 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
YKR++K+GEG+Y VYK + + +VA+K+I+L+ + EG+P TAIRE SLL+ L+ N
Sbjct: 108 YKRIDKLGEGSYATVYKC-ESKLDGSIVALKEIKLQFQ-EGLPFTAIREASLLRNLRHAN 165
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHA 126
IV L+DI + H+L VFE++ +DL +Y+E L IK + QL +G+ +CH
Sbjct: 166 IVSLHDIFYQH-HQLTFVFEYMKMDLSKYLEQ--NVYGLDSIDIKLLLFQLLRGLDFCHR 222
Query: 127 HRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQY 186
+I+HRDLKPQNLL++ DG LKL DFGLARA VP R Y+HE+VTLWYR P+VL+G Y
Sbjct: 223 KKILHRDLKPQNLLLDEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGSTDY 282
Query: 187 STGVDVWSIGCIFAEMCNRKPLFSGDSEI------DQIFKIFRVLGTPNERTWPDIIYLP 240
ST +D+W +GCIFAE+C LF G + DQ+ IF + GTP+E+ WP++ LP
Sbjct: 283 STSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLP 342
Query: 241 DF-KTTFPKWNRRNLSEVIP---SLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+ FP++ + V P + G +LL L+ P R+SA A+ HPYF
Sbjct: 343 GYTPELFPRYRELSFIAVNPMFTKILKTGQELLGMLLQLRPESRVSAASAMLHPYF 398
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 251 bits (642), Expect = 7e-67
Identities = 131/305 (42%), Positives = 192/305 (62%), Gaps = 17/305 (5%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLES----EDEGVPSTAIREISLL 59
+ +++L K+ EGTYG+VYKA D + + +VA+KKI+++ E+ G P T++REI++L
Sbjct: 294 VNEFQKLNKINEGTYGIVYKARDEKTKE-IVALKKIKMKEDRFEEEYGFPLTSLREINIL 352
Query: 60 KELKDDNIVRLYDIV--HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQL 117
IV + ++V + + +Y+V E L+ DL+ M+ + +P + +K MMQL
Sbjct: 353 LSCNHPAIVNVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDR--RKEPFSTSEVKCLMMQL 410
Query: 118 CKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAP 177
G+ Y H + IIHRDLKP NLL+N G LK+ DFG+AR +G P++ YT ++T WYR P
Sbjct: 411 LDGLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSPIKPYTQMVITQWYRPP 470
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
E+LLG K+YST VD+WS+GCI AE+ ++KPLF G SE+DQ+ KIF VLGTPNE WP
Sbjct: 471 ELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWPGFS 530
Query: 238 YLPDFKTTFPKWNRRNLSEVIPS--------LDANGIDLLDKLITYDPIHRISAKRAVQH 289
P+ K FP L + P+ L G DLL+ L+T DP R++ + A+ H
Sbjct: 531 SFPNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVEDALNH 590
Query: 290 PYFKE 294
+F E
Sbjct: 591 GWFHE 595
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 245 bits (625), Expect = 6e-65
Identities = 131/296 (44%), Positives = 189/296 (63%), Gaps = 12/296 (4%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDE---GVPSTAIREISL 58
S Y++L+ +GEG + VYKA D ++ N++VA+KKI+L E G+ TA+REI L
Sbjct: 7 SRAKRYEKLDFLGEGQFATVYKARD-KNTNQIVAIKKIKLGHRSEAKDGINRTALREIKL 65
Query: 59 LKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPL--GGNIIKKFMMQ 116
L+EL NI+ L D ++ + LVF+F++ DL E I KD L + IK +M+
Sbjct: 66 LQELSHPNIIGLLDAFGHKSN-ISLVFDFMETDL----EVIIKDNSLVLTPSHIKAYMLM 120
Query: 117 LCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRA 176
+G+ Y H H I+HRDLKP NLL++ +G LKL DFGLA++FG P RAYTH++VT WYRA
Sbjct: 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA 180
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE+L G + Y GVD+W++GCI AE+ R P GDS++DQ+ +IF LGTP E WPD+
Sbjct: 181 PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM 240
Query: 237 IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
LPD+ TF + L + + + +DL+ L ++P RI+A +A++ YF
Sbjct: 241 CSLPDY-VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYF 295
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 244 bits (624), Expect = 8e-65
Identities = 133/300 (44%), Positives = 193/300 (64%), Gaps = 16/300 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ L ++ EGTYGVVY+A D R N +VA+K++++E E EG P T++REI+ L + + N
Sbjct: 558 FQCLNRIEEGTYGVVYRAKDKR-TNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPN 616
Query: 67 IVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIP-KDQPLGGNIIKKFMMQLCKGIAYC 124
IV + +IV S+ K+++V ++++ DLK ME++ + Q +K QL + +A+
Sbjct: 617 IVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHL 676
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H + I+HRDLK NLL++ G LK+GDFGLAR +G P++ YT +VTLWYRAPE+LL
Sbjct: 677 HDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSP 736
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK- 243
YST +DVWS+GCIFAE PLF G SEID++ +IF+ LGTPNE+ WP LP K
Sbjct: 737 VYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKN 796
Query: 244 --------TTFP-KWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
T +P R++ E + G+ LL L+TYDP R+SA A++H +FKE
Sbjct: 797 MLSQNSQFTEYPVSQLRKHFQEKTSEM---GLSLLQGLLTYDPKQRLSADAALKHGFFKE 853
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 241 bits (615), Expect = 9e-64
Identities = 134/308 (43%), Positives = 185/308 (59%), Gaps = 23/308 (7%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
+ LT+Y L+++GEGTYG VYKAV+ VA+K++RLE+E EG P TAIREI +L++
Sbjct: 306 TNLTHYTMLDQIGEGTYGQVYKAVN-NLTGEQVALKRVRLENEKEGFPITAIREIKILRQ 364
Query: 62 LKDDNIVRLYDIVHSDAH---------KLYLVFEFLDLDLKRYMES-----IPKDQPLGG 107
L NIVRL DIV D YLVFE++D DL +ES KDQ
Sbjct: 365 LHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQ---- 420
Query: 108 NIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTH 167
I QL +G+AY H +HRD+K N+L+N G LK+ D GLAR + R YT+
Sbjct: 421 --ICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTN 478
Query: 168 EIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGT 227
++TLWYR PE+LLG ++Y +DVWS GC+ E+ RKPLF+G++E Q+ I +V G+
Sbjct: 479 RVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGS 538
Query: 228 PNERTWPDIIYLPDFKTTFPK--WNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKR 285
PN WP++ L + T K + RR E + +DLLDK++T +P RISAK
Sbjct: 539 PNVDNWPELTELVGWNTFRMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKE 598
Query: 286 AVQHPYFK 293
A+ HP+ +
Sbjct: 599 ALNHPWIR 606
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 240 bits (613), Expect = 2e-63
Identities = 137/292 (46%), Positives = 184/292 (62%), Gaps = 9/292 (3%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
++Y LEK+GEG+Y VYK + R ++VA+K I + +E EGVP TAIRE SLLK LK
Sbjct: 50 SSYLNLEKLGEGSYATVYKGIS-RINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKH 107
Query: 65 DNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
NIV L+DI+H+ L VFE++ DL +YM P L + ++ FM QL +G+AY
Sbjct: 108 ANIVLLHDIIHTK-ETLTFVFEYMHTDLAQYMSQHPGG--LHPHNVRLFMFQLLRGLAYI 164
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H ++HRDLKPQNLLI+ G LKL DFGLARA +P + Y+ E+VTLWYR P+ LLG
Sbjct: 165 HHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGAT 224
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEI-DQIFKIFRVLGTPNERTWPDIIYLPDFK 243
+YS+ +D+W GCIF EM +PLF G S I +Q+ KI+ VLG P E TWP + LP++
Sbjct: 225 EYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYN 284
Query: 244 TT-FPKWNRRNLSEVIPSLD--ANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
FP R+L V L DL +++ P R+SA+ A+ H YF
Sbjct: 285 PEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYF 336
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 239 bits (610), Expect = 3e-63
Identities = 126/309 (40%), Positives = 196/309 (62%), Gaps = 32/309 (10%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
+++LE++GEGTYG VY A +++ +VA+KKIR+++E EG P TAIREI +LK+L +N
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIK-TGEIVALKKIRMDNEREGFPITAIREIKILKKLHHEN 84
Query: 67 IVRLYDIVHS-----------DAHK----LYLVFEFLDLDLKRYME------SIPKDQPL 105
+++L +IV S D +K +Y+VFE++D DL + ++P+
Sbjct: 85 VIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQ---- 140
Query: 106 GGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA- 164
IK +M QL G+ YCH ++++HRD+K NLLI+ +GNLKL DFGLAR++
Sbjct: 141 ----IKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGN 196
Query: 165 YTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRV 224
T+ ++TLWYR PE+LLG +Y +D+WS+GCIFAE+ + KP+ G +E +Q+ KIF +
Sbjct: 197 LTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFEL 256
Query: 225 LGTPNERTWPDIIYLPDFKTTFP-KWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISA 283
G+P+E+ WP + +P F P + +R + E D + ++LL+K++ DP RISA
Sbjct: 257 CGSPDEKLWPGVSKMPWFNNFKPARPLKRRVREFFRHFDRHALELLEKMLVLDPAQRISA 316
Query: 284 KRAVQHPYF 292
K A+ YF
Sbjct: 317 KDALDAEYF 325
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 238 bits (606), Expect = 1e-62
Identities = 128/291 (43%), Positives = 181/291 (61%), Gaps = 12/291 (4%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDE---GVPSTAIREISLLKELK 63
Y +L +GEG + VYKA D N++VA+KKI+ S ++ G+ TA+REI +L+EL+
Sbjct: 12 YAKLSFLGEGQFATVYKARDTV-TNQIVAVKKIKKGSREDARDGINRTALREIKILQELQ 70
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQP--LGGNIIKKFMMQLCKGI 121
+NI+ L D V + LVF+F+D DL E I KD L IK + + KG+
Sbjct: 71 HENIIGLVD-VFGQLSNVSLVFDFMDTDL----EVIIKDNKIILTQANIKAYAIMTLKGL 125
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y H + I+HRDLKP NLL+N DG LK+GDFGLA++FG P R YTH +VT WYR+PE+L
Sbjct: 126 EYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLF 185
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
G +QY TGVD+W++GCI AE+ R P GDS++DQ+ +IF LGTP E WP + L D
Sbjct: 186 GARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHD 245
Query: 242 FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+ F + L + + + I L+ +L +P+ R+S + A+ PYF
Sbjct: 246 Y-LQFRNFPGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 237 bits (605), Expect = 1e-62
Identities = 128/300 (42%), Positives = 184/300 (60%), Gaps = 15/300 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
++ + ++GEGTYG VYKA D H N +VA+KK+RLE E EG P TA+REI +L++L N
Sbjct: 804 FEMIAQIGEGTYGQVYKARD-HHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRN 862
Query: 67 IVRLYDIV---------HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQL 117
IV L++IV D YLVFE++D DL +ES D N M QL
Sbjct: 863 IVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNA--SIMKQL 920
Query: 118 CKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP--LRAYTHEIVTLWYR 175
G+ YCH +HRD+K N+L+N G +KL DFGLAR + R YT++++TLWYR
Sbjct: 921 LDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYR 980
Query: 176 APEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPD 235
PE+LLG ++Y +DVWS GCI E+ ++PLF ++E+ Q+ I ++ G+P WP+
Sbjct: 981 PPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPN 1040
Query: 236 IIYLPDFKT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+I LP F T K +RR L E + A +DLLDK++ DP RI+A+ A++ P+ ++
Sbjct: 1041 VIKLPLFHTLKQKKTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRK 1100
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 235 bits (600), Expect = 5e-62
Identities = 125/311 (40%), Positives = 195/311 (62%), Gaps = 36/311 (11%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
+++LE++GEGTYG VY A +++ +VA+KKIR+++E EG P TAIREI +LK+L +N
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIK-TGEIVALKKIRMDNEREGFPITAIREIKILKKLHHEN 84
Query: 67 IVRLYDIVHS-----------DAHK----LYLVFEFLDLDLKRYME------SIPKDQPL 105
++ L +IV S D +K +Y+VFE++D DL + ++P+
Sbjct: 85 VIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQ---- 140
Query: 106 GGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA- 164
IK +M QL G+ YCH ++++HRD+K NLLI+ +GNLKL DFGLAR++
Sbjct: 141 ----IKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGN 196
Query: 165 YTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRV 224
T+ ++TLWYR PE+LLG +Y +D+WS+GCIFAE+ N KP+ G +E +Q+ KI+ +
Sbjct: 197 LTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYEL 256
Query: 225 LGTPNERTWPDIIYLP---DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
G+P+E WP + +P K++ P +R + E+ D + ++LL+K++ DP RI
Sbjct: 257 CGSPDESNWPGVSKMPWYNQMKSSRPL--KRRVREIYRHFDRHALELLEKMLVLDPSQRI 314
Query: 282 SAKRAVQHPYF 292
AK A+ YF
Sbjct: 315 CAKDALDAEYF 325
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 234 bits (598), Expect = 8e-62
Identities = 126/297 (42%), Positives = 181/297 (60%), Gaps = 22/297 (7%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+GEGTYG VYKA D + +VA+KK+RL++E EG P TAIREI +L++L ++V + +
Sbjct: 733 IGEGTYGQVYKARD-KDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKE 791
Query: 73 IV---------HSDAHKLYLVFEFLDLDLKRYMES----IPKDQPLGGNIIKKFMMQLCK 119
IV D YLVFE++D DL +ES +D IK FM QL +
Sbjct: 792 IVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDH------IKSFMKQLME 845
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP-LRAYTHEIVTLWYRAPE 178
G+ YCH +HRD+K N+L+N G +KL DFGLAR + R YT++++TLWYR PE
Sbjct: 846 GLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPE 905
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
+LLG ++Y+ +DVWS GCI E+ +KP+F + E+ Q+ I R+ G+P WPD+I
Sbjct: 906 LLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIK 965
Query: 239 LPDFKTTFPKWN-RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
LP F T PK RR L E + + +DLLD ++T DP R +A++ +Q + K+
Sbjct: 966 LPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 234 bits (598), Expect = 8e-62
Identities = 125/293 (42%), Positives = 179/293 (60%), Gaps = 14/293 (4%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+GEGTYG VYKA D + +VA+KK+RL++E EG P TAIREI +L++L +I+ + +
Sbjct: 711 IGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKE 769
Query: 73 IV---------HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
IV D YLVFE++D DL +ES N IK FM QL +G+ Y
Sbjct: 770 IVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH--FNENHIKSFMRQLMEGLDY 827
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP-LRAYTHEIVTLWYRAPEVLLG 182
CH +HRD+K N+L+N G +KL DFGLAR + R YT++++TLWYR PE+LLG
Sbjct: 828 CHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLG 887
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
++Y+ +DVWS GCI E+ +KP+F + E+ Q+ I R+ G+P WPD+I LP F
Sbjct: 888 EERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYF 947
Query: 243 KTTFPKWN-RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
T PK RR L E + A +DL D ++ DP R +A++A+Q + ++
Sbjct: 948 NTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 234 bits (598), Expect = 8e-62
Identities = 125/293 (42%), Positives = 179/293 (60%), Gaps = 14/293 (4%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+GEGTYG VYKA D + +VA+KK+RL++E EG P TAIREI +L++L +I+ + +
Sbjct: 711 IGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKE 769
Query: 73 IV---------HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
IV D YLVFE++D DL +ES N IK FM QL +G+ Y
Sbjct: 770 IVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVH--FNENHIKSFMRQLMEGLDY 827
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP-LRAYTHEIVTLWYRAPEVLLG 182
CH +HRD+K N+L+N G +KL DFGLAR + R YT++++TLWYR PE+LLG
Sbjct: 828 CHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLG 887
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
++Y+ +DVWS GCI E+ +KP+F + E+ Q+ I R+ G+P WPD+I LP F
Sbjct: 888 EERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYF 947
Query: 243 KTTFPKWN-RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
T PK RR L E + A +DL D ++ DP R +A++A+Q + ++
Sbjct: 948 NTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 231 bits (588), Expect = 1e-60
Identities = 129/301 (42%), Positives = 187/301 (61%), Gaps = 16/301 (5%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEG---VPSTAIREISLLKE 61
+ Y+ + ++G G YG VYKA D H VA+K +R+ + G +P + +RE++LL+
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARD-PHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 62 LK---DDNIVRLYDIVHSDAH----KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFM 114
L+ N+VRL D+ + K+ LVFE +D DL+ Y++ P L IK M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPG-LPAETIKDLM 121
Query: 115 MQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWY 174
Q +G+ + HA+ I+HRDLKP+N+L+ G +KL DFGLAR + + A T +VTLWY
Sbjct: 122 RQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQM-ALTPVVVTLWY 180
Query: 175 RAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWP 234
RAPEVLL Y+T VD+WS+GCIFAEM RKPLF G+SE DQ+ KIF ++G P E WP
Sbjct: 181 RAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWP 239
Query: 235 DIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ LP + FP R + V+P ++ +G LL +++T++P RISA RA+QH Y +
Sbjct: 240 RDVSLP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHK 297
Query: 295 E 295
+
Sbjct: 298 D 298
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 231 bits (588), Expect = 1e-60
Identities = 121/291 (41%), Positives = 184/291 (62%), Gaps = 5/291 (1%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
+++L ++GEGTYG+VY+A D + + +VA+KK+R++ E +G+P +++REI+LL L+ N
Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQ-TDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPN 97
Query: 67 IVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV L ++V + ++LV + + DL +E++P P +K ++Q+ +G+ Y H
Sbjct: 98 IVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT--PFSEAQVKCIVLQVLRGLQYLH 155
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ IIHRDLK NLL+ G +K DFGLARA+GVP++ T ++VTLWYRAPE+LLG
Sbjct: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
+T +D+W++GCI AE+ +PL G SEI QI I ++LGTP+E WP LP +
Sbjct: 216 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 275
Query: 245 TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+ K NL P L G+ LL L YDP R +A ++ YFKE+
Sbjct: 276 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEK 326
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 231 bits (588), Expect = 1e-60
Identities = 121/291 (41%), Positives = 184/291 (62%), Gaps = 5/291 (1%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
+++L ++GEGTYG+VY+A D + + +VA+KK+R++ E +G+P +++REI+LL L+ N
Sbjct: 10 FEKLNRIGEGTYGIVYRARDTQ-TDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPN 68
Query: 67 IVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV L ++V + ++LV + + DL +E++P P +K ++Q+ +G+ Y H
Sbjct: 69 IVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT--PFSEAQVKCIVLQVLRGLQYLH 126
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ IIHRDLK NLL+ G +K DFGLARA+GVP++ T ++VTLWYRAPE+LLG
Sbjct: 127 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 186
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF-KT 244
+T +D+W++GCI AE+ +PL G SEI QI I ++LGTP+E WP LP +
Sbjct: 187 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 246
Query: 245 TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+ K NL P L G+ LL L YDP R +A ++ YFKE+
Sbjct: 247 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEK 297
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 229 bits (584), Expect = 4e-60
Identities = 128/299 (42%), Positives = 189/299 (62%), Gaps = 8/299 (2%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREIS-LLKEL 62
+ Y+ + +V EGT+GVVY+ D R + +VA+K++++E E EG P TA+REI+ LLK
Sbjct: 353 IDEYECVNRVDEGTFGVVYRGKDKR-TDEIVALKRLKMEKEKEGFPITALREINMLLKAG 411
Query: 63 KDDNIVRLYDIV-HSDAHKLYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
NIV + +I+ S+ K+Y+ EF++ D+K ++++ + ++ K + QL G
Sbjct: 412 NHPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSG 471
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
I + H I+HRDLK NLL++ G LK+ DFGLAR +G PL+ +T +VTLWYR+PE+L
Sbjct: 472 IEHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELL 531
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
LG + YST VD+WS+GCI AE KPLF G E++QI KIF +GTP E WP + L
Sbjct: 532 LGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELD 591
Query: 241 DFKT-TFPKWNRRNLSEVIPS---LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+K TF K+ L + + L+ G LL+ L+T DP +R SA +A+ H +F EE
Sbjct: 592 GWKALTFEKYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTEE 650
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 229 bits (583), Expect = 5e-60
Identities = 126/304 (41%), Positives = 182/304 (59%), Gaps = 16/304 (5%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E Y+++ K+G+GT+G V+KA + + + VAMKK+ +++E EG P TA+REI +L+ L
Sbjct: 46 ESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLL 105
Query: 63 KDDNIVRLYDIVHSDA-------HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMM 115
K +N+V L +I + A YLVF+F + DL + ++ LG IKK M
Sbjct: 106 KHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGE--IKKVMQ 163
Query: 116 QLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA----YTHEIVT 171
QL G+ Y H+++I+HRD+K N+LI + G LKL DFGLARAF +P YT+ +VT
Sbjct: 164 QLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVT 223
Query: 172 LWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNER 231
LWYR PE+LLG + Y VD+W GCI AEM R P+ G++E Q+ I ++ G+
Sbjct: 224 LWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPD 283
Query: 232 TWPDIIYLPDFKT-TFPKWNRRNLSEVIPSL--DANGIDLLDKLITYDPIHRISAKRAVQ 288
WP + L +K+ PK +R + E + D G DLLDKL+T DP RI A A+
Sbjct: 284 VWPGVEELELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALN 343
Query: 289 HPYF 292
H +F
Sbjct: 344 HDFF 347
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 223 bits (569), Expect = 2e-58
Identities = 126/297 (42%), Positives = 186/297 (62%), Gaps = 13/297 (4%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
NY+ L +GEG YG VY+A D+ N +VA+KK+R+ + GVP + +REISLLK+L
Sbjct: 25 NYQELNIIGEGAYGTVYRARDVITGN-IVALKKVRISLNENGVPMSTLREISLLKQLNAS 83
Query: 66 N---IVRLYDI---VHSDAHKLYL-VFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
N IV+LY++ + D L L VFE ++ DL ++ +PK + I++ +L
Sbjct: 84 NHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSG-MSPPTIQRLSRELL 142
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
G+ + H+HRIIHRDLKPQNLL++ G+LK+ DFGLA+ +G ++ T +VTLWYRAPE
Sbjct: 143 TGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAPE 201
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
VLL + Y++ VD+WS CI EM NR+ LF G SE +Q+ +IF + G P E+ WP I
Sbjct: 202 VLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTIS 260
Query: 239 LPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+ FP+ + + + P L DLL+K+++YD R SA ++H YF++E
Sbjct: 261 VA--LEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQQE 315
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 219 bits (557), Expect = 5e-57
Identities = 119/295 (40%), Positives = 176/295 (59%), Gaps = 11/295 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y R+ +VGEGTYG VYKA + + ++VA+KK+RL+ E EG P T+IREI LL+ N
Sbjct: 183 YLRIMQVGEGTYGKVYKAKNTNTE-KLVALKKLRLQGEREGFPITSIREIKLLQSFDHPN 241
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHA 126
+ + +I+ +Y++FE+ D DL + + K+ + + K QL G+ Y H
Sbjct: 242 VSTIKEIMVESQKTVYMIFEYADNDLSGLL--LNKEVQISHSQCKHLFKQLLLGMEYLHD 299
Query: 127 HRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-YTHEIVTLWYRAPEVLLGGKQ 185
++I+HRD+K N+LI+ GNLK+ DFGLAR RA YT+ ++TLWYR PE+LLG
Sbjct: 300 NKILHRDVKGSNILIDNQGNLKITDFGLARKMNS--RADYTNRVITLWYRPPELLLGTTN 357
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTT 245
Y T VD+W GC+ E+ N+ +F G +E++QI IF+++GTP +WP + +P F
Sbjct: 358 YGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMI 417
Query: 246 FPKWNRR---NLSEVIPSL--DANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
P+ + N SE S+ + + L L+ YD R SA A+Q YFKEE
Sbjct: 418 MPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFKEE 472
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 218 bits (554), Expect = 1e-56
Identities = 119/315 (37%), Positives = 187/315 (58%), Gaps = 27/315 (8%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y + K+GEGTYG+V+ A R +A+KK + + +GV TAIREI LL+E+
Sbjct: 22 LQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREIS 81
Query: 64 DDNIVRLYDI-VHSDAHKLYLVFEFLDLDL----KRYMESIPKDQPLGGNIIKKFMMQLC 118
+N+V+L ++ ++ LYL F++ + DL + + + + L +K + QL
Sbjct: 82 HENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKV--GHSLNTYTVKSLLWQLL 139
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRD----GNLKLGDFGLARAFGVPLRAYTHE--IVTL 172
G+ Y H++ IIHRDLKP N+L+ D G +K+ DFGLAR + PL+ + +VT+
Sbjct: 140 NGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTI 199
Query: 173 WYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDS--------EIDQIFKIFRV 224
WYRAPE+LLG K Y++ VD+W++GCIFAE+ KPLF G ++DQ+ KIF++
Sbjct: 200 WYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKI 259
Query: 225 LGTPNERTWPDIIYLPDFKTTFP-----KWNRRNLSEVIP-SLDANGIDLLDKLITYDPI 278
LG P WP ++ LP ++ K++ L V+ + + DLL K++ YDP+
Sbjct: 260 LGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLEYDPL 319
Query: 279 HRISAKRAVQHPYFK 293
RI+A +A++H YF+
Sbjct: 320 KRITASQALEHEYFR 334
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 218 bits (554), Expect = 1e-56
Identities = 114/291 (39%), Positives = 182/291 (62%), Gaps = 5/291 (1%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
++ +++L +VGEG+YG+VY+A D R N +VA+KK+R++ E +G+P + +REI +LK+
Sbjct: 50 VSEFEKLNRVGEGSYGIVYRARDTR-SNEIVALKKVRMDQEKDGLPISGLREIMILKQCH 108
Query: 64 DDNIVRLYDIVHSDA-HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
+NIVRL ++V + ++LV +F + DL ++++ QP + +K +Q+ K +
Sbjct: 109 HENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNM--SQPFTESEVKCITLQVLKALK 166
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
Y H+ +IHRDLK NLL+ G +K+ DFGLAR F P + T ++VTLWYRAPE+LLG
Sbjct: 167 YLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLG 226
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
+ ++T VD+W+ GCI E+ KPL G+SEI Q+ I +LG P+E WP LP
Sbjct: 227 CRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAV 286
Query: 243 KT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+ T + NL+ + +G +LL+ L Y+P R +A+ ++ YF
Sbjct: 287 QNFTLSQQPYNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKYF 337
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 216 bits (549), Expect = 4e-56
Identities = 122/314 (38%), Positives = 179/314 (56%), Gaps = 27/314 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y+ EK+G+GT+G VYK + L Q R VAMKKI + E + P TA REI++LK L
Sbjct: 59 HYREDEKLGQGTFGEVYKGIHLETQ-RQVAMKKIIVSVEKDLFPITAQREITILKRLNHK 117
Query: 66 NIVRLYDIVH-----------SDAHK-LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKF 113
NI++L ++V+ S+ HK Y++ ++ DL + + + + IK
Sbjct: 118 NIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCD--IKNM 175
Query: 114 MMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF-GVPLRA-------- 164
M+Q+ +G+ Y H + +HRD+K N+LI+ +G LKL DFGLAR + G P
Sbjct: 176 MLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGS 235
Query: 165 ---YTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKI 221
YT +VT WYRAPE++LG KQY+T VD+W +GC+FAE +KP+ G ++IDQ I
Sbjct: 236 GAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVI 295
Query: 222 FRVLGTPNERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
F++LGTP E W YLP + T + L G+D L +L+ DP R+
Sbjct: 296 FKLLGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRL 355
Query: 282 SAKRAVQHPYFKEE 295
+A A HP+FKE+
Sbjct: 356 TAMSAKHHPWFKED 369
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 216 bits (549), Expect = 4e-56
Identities = 117/302 (38%), Positives = 182/302 (59%), Gaps = 19/302 (6%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRV------------VAMKKIRLESEDEGVPST 51
+ Y R ++GEGTY V+Y Q++ VA+KKI+ +G +
Sbjct: 1 MKTYIRERRLGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEIS 60
Query: 52 AIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIK 111
AIREI LK + +VRL D D +++V E+++ +L+ + + D+ + IK
Sbjct: 61 AIREIKSLKRIDSKYVVRLIDTFVYDKC-VHIVLEYVETNLENVIRN--SDKIIMPGDIK 117
Query: 112 KFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVT 171
+++ + +G+ CH IIHRD+KP N+LI +G +KL DFGL R G T + VT
Sbjct: 118 AWILMVLRGVYECHRLFIIHRDIKPNNILITSEGMVKLADFGLTRGIG---NRMTPQAVT 174
Query: 172 LWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNER 231
WYRAPE+L+G + Y + VD+WS+GC+FAE+ R PLF+GD++I Q+ IFR LGTP ER
Sbjct: 175 RWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTPVER 234
Query: 232 TWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
WP + LP+F F ++ + +L+ + + ++ +DLL+KL+T +P +RIS A++HPY
Sbjct: 235 EWPGVSTLPEF-LDFQQYPKASLNGLFSAASSDALDLLEKLLTLNPCNRISCDDAIKHPY 293
Query: 292 FK 293
FK
Sbjct: 294 FK 295
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 214 bits (545), Expect = 1e-55
Identities = 127/315 (40%), Positives = 182/315 (57%), Gaps = 30/315 (9%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
S LT+Y +EK+GEGT+G VYK+ R +V A+K+I + +E EG P TAIREI +LK
Sbjct: 31 SHLTDYHLMEKLGEGTFGEVYKS-QRRKDGKVYALKRILMHTEKEGFPITAIREIKILKS 89
Query: 62 LKDDNIVRLYDIV-------HSDAHKLYLVFEFLDLDLKRYME--SIPKDQPLGGNIIKK 112
+K +NI+ L D+ H +Y+V ++D DL +E S+ +P IK
Sbjct: 90 IKHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQ----IKC 145
Query: 113 FMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF----------GVP- 161
+M QL G Y H I+HRDLK NLLI+ G LK+ DFGLAR G+P
Sbjct: 146 YMKQLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPP 205
Query: 162 --LRAYTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIF 219
R YT +VT WYR+PE+LLG ++Y+T +D+WS+GCI AEM +P+ G S++DQ+
Sbjct: 206 PNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLD 265
Query: 220 KIFRVLGTPNERTWPDIIYLPDFK--TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDP 277
KIFR+ G+P + T P+ LP + +FP + R L + L ++T +P
Sbjct: 266 KIFRLCGSPTQATMPNWEKLPGCEGVRSFPS-HPRTLETAFFTFGKEMTSLCGAILTLNP 324
Query: 278 IHRISAKRAVQHPYF 292
R+SA A++H YF
Sbjct: 325 DERLSASMALEHEYF 339
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 214 bits (545), Expect = 1e-55
Identities = 119/304 (39%), Positives = 180/304 (59%), Gaps = 17/304 (5%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E++ Y++L K+G+GT+G V+KA R + VA+KK+ +E+E EG P TA+REI +L+ L
Sbjct: 15 EVSKYEKLAKIGQGTFGEVFKARH-RKTGQKVALKKVLMENEKEGFPITALREIKILQLL 73
Query: 63 KDDNIVRLYDIVHSDAH-------KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMM 115
K +N+V L +I + A +YLVF+F + DL + ++ L IK+ M
Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSE--IKRVMQ 131
Query: 116 QLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA----YTHEIVT 171
L G+ Y H ++I+HRD+K N+LI RDG LKL DFGLARAF + + YT+ +VT
Sbjct: 132 MLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVT 191
Query: 172 LWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNER 231
LWYR PE+LLG + Y +D+W GCI AEM R P+ G++E Q+ I ++ G+
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPE 251
Query: 232 TWPDI-IYLPDFKTTFPKWNRRNLSEVIPSL--DANGIDLLDKLITYDPIHRISAKRAVQ 288
WP++ Y K K +R + + + + D +DL+DKL+ DP RI + A+
Sbjct: 252 VWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALN 311
Query: 289 HPYF 292
H +F
Sbjct: 312 HDFF 315
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 214 bits (545), Expect = 1e-55
Identities = 119/292 (40%), Positives = 179/292 (60%), Gaps = 11/292 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
+++LEK+G+GTY VY+A DL H N++VA+KK+R + D REI +++ L N
Sbjct: 213 FEKLEKIGQGTYSSVYRARDLLH-NKIVALKKVRFDLNDMESVKFMAREIIVMRRLDHPN 271
Query: 67 IVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
+++L ++ + + LYLVFE++D DL + S+P + + K +M QL G+ +CH
Sbjct: 272 VLKLEGLITAPVSSSLYLVFEYMDHDLLG-LSSLPGVKFTEPQV-KCYMRQLLSGLEHCH 329
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAY--THEIVTLWYRAPEVLLGG 183
+ ++HRD+K NLLI+ G LK+ DFGLA F P ++ T +VTLWYR PE+LLG
Sbjct: 330 SRGVLHRDIKGSNLLIDSKGVLKIADFGLATFFD-PAKSVSLTSHVVTLWYRPPELLLGA 388
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW--PDIIYLPD 241
Y GVD+WS GCI E+ KP+ G +E++Q+ KIF++ G+P E W +
Sbjct: 389 SHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPTENYWRKQKLPSSAG 448
Query: 242 FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
FKT P RR +SE+ A+ + LL+ L++ DP HR SA RA++ YFK
Sbjct: 449 FKTAIP--YRRKVSEMFKDFPASVLSLLETLLSIDPDHRSSADRALESEYFK 498
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 213 bits (543), Expect = 2e-55
Identities = 123/298 (41%), Positives = 178/298 (59%), Gaps = 18/298 (6%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
S+ Y + KVGEGTY VV+ + NR VA+KKI++ +G+ +A+REI L+E
Sbjct: 6 SDKWTYVKERKVGEGTYAVVFLGRQ-KETNRRVAIKKIKVGQFKDGIDISALREIKFLRE 64
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKD-----QPLGGNIIKKFMMQ 116
+ DN++ L D V S L ++ EFLD DL E + KD QP IK +M+
Sbjct: 65 SRHDNVIELVD-VFSTKSNLNIILEFLDSDL----EMLIKDKFIVFQPAH---IKSWMVM 116
Query: 117 LCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRA 176
L +G+ + H+ I+HRDLKP NLLI+ DG LKL DFGL+R FG P +H+++T WYR
Sbjct: 117 LLRGLHHIHSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSHM-SHQVITRWYRP 175
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE+ +G + Y TGVD+WS+GCIFAE+ R P G+S++DQ+ IFR LGTP +
Sbjct: 176 PELFMGCRSYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSM 235
Query: 237 IYLPDF--KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
LP++ P N + + + IDLL ++ Y+P R +A++A++H YF
Sbjct: 236 QQLPNYVEMKHIPPPN-GGMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYF 292
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 213 bits (541), Expect = 3e-55
Identities = 114/293 (38%), Positives = 177/293 (59%), Gaps = 9/293 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y++++++GEGTYG VYKA++ + +VA+K+IRLE E +G P T +RE+ +L+ L+ N
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGD-LVALKRIRLEQEKDGFPITTVREVKILQRLRHKN 335
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHA 126
IVRL +I+ + +Y+VFE++D DL + + G IK Q+ + +AY H
Sbjct: 336 IVRLLEIM-VEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGN--IKHLSKQIFEALAYLHH 392
Query: 127 HRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA--YTHEIVTLWYRAPEVLLGGK 184
++HRD+K N+L+N +G+LK DFGLAR F ++ YT+ ++TLW+R PE+LLG
Sbjct: 393 RGVLHRDIKGSNILLNNNGDLKFADFGLAR-FNTSSKSANYTNRVITLWFRPPELLLGET 451
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKT 244
Y T VD+WS GCI E+ KP F G EI Q+ I+ ++GTP+ +WP++ LP ++
Sbjct: 452 AYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVKNLPWYEL 511
Query: 245 TFPKWNRRN--LSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
P +++ + L IDL KL+ +P R SA + H YF E
Sbjct: 512 LKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTSE 564
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 209 bits (533), Expect = 3e-54
Identities = 123/303 (40%), Positives = 181/303 (59%), Gaps = 13/303 (4%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREIS-LLKEL 62
++ Y L + EGTYG V++ + R + VVA+K+ ++E E EG P TA+REI+ LLK
Sbjct: 396 ISEYVILNVIAEGTYGEVFRGKNTR-TDEVVALKRFKMEKEKEGFPITALREINMLLKAG 454
Query: 63 KDDNIVRLYDI-VHSDAHKLYLVFEFLDLDLKRYMESI-PKDQPLGGNIIKKFMMQLCKG 120
+NIV + +I V S ++Y+ E+++ D+K ++ + ++Q K M QL G
Sbjct: 455 AHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSG 514
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPL-----RAYTHEIVTLWYR 175
I + H I+HRDLK NLLI+ G LK+ DFGLAR +G T +VTLWYR
Sbjct: 515 IEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYR 574
Query: 176 APEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPD 235
+PE+LL K YST VD+WSIGCI AE KP+F GDSE +Q+ +IF+++GTP E+ WPD
Sbjct: 575 SPELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPD 634
Query: 236 IIYLPDFK-TTFPKWNRRNLSEVIPS---LDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
I L + FP L + ++ G DLL+ ++ +P +R++A A+QH +
Sbjct: 635 IKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDW 694
Query: 292 FKE 294
F E
Sbjct: 695 FSE 697
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 209 bits (533), Expect = 3e-54
Identities = 118/298 (39%), Positives = 182/298 (60%), Gaps = 15/298 (5%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
+ +++LEK+G+GTY VYKA DL + N++VA+K++R + D REI +++ L
Sbjct: 135 STFEKLEKIGQGTYSSVYKARDLTN-NKIVALKRVRFDLSDLESVKFMAREIIVMRRLDH 193
Query: 65 DNIVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
N+++L ++ + + LYLVFE++D DL + SIP + +K +M QL G+ +
Sbjct: 194 PNVLKLEGLITASVSSSLYLVFEYMDHDLVG-LASIPGIK-FSEPQVKCYMQQLLSGLHH 251
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFG----VPLRAYTHEIVTLWYRAPEV 179
CH+ ++HRD+K NLLI+ +G LK+ DFGLA F VPL T +VTLWYR PE+
Sbjct: 252 CHSRGVLHRDIKGSNLLIDSNGVLKIADFGLATFFDPQNCVPL---TSRVVTLWYRPPEL 308
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
LLG Y GVD+WS GCI E+ + KP+ +G +E++Q+ KIF++ G+P E W +
Sbjct: 309 LLGACHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPTEDYWRKLKLP 368
Query: 240 PD--FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
P F+ P R ++E+ L N + LL+ L++ DP R SA RA++ YF+ E
Sbjct: 369 PSAAFRPALP--YGRRVAEMFKDLPTNVLSLLEALLSIDPDRRGSAARALESEYFRTE 424
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 208 bits (529), Expect = 8e-54
Identities = 116/296 (39%), Positives = 180/296 (60%), Gaps = 13/296 (4%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++++L+K+G+GTY +VYKA DL ++VAMKK+R + D REI++L++L
Sbjct: 140 SFEKLDKIGQGTYSIVYKARDLE-TGKIVAMKKVRFANMDPESVRFMAREINILRKLDHP 198
Query: 66 NIVRLYDIVHSD-AHKLYLVFEFLDLDLK--RYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
N+++L +V S + L+LVFE+++ DL + +P IK FM QL G+
Sbjct: 199 NVMKLQCLVTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQ----IKCFMKQLLCGLE 254
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPL-RAYTHEIVTLWYRAPEVLL 181
+CH+ I+HRD+K NLL+N DG LK+GDFGLA + + T +VTLWYRAPE+LL
Sbjct: 255 HCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPLTSRVVTLWYRAPELLL 314
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY--L 239
G +Y +D+WS+GCI AE+ KP+ G +E++Q+ KIF++ G+P+E W +
Sbjct: 315 GSTEYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEEFWNTTKFPQA 374
Query: 240 PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+K P +R L E +L ++ +DLLDKL++ +P R SA + +F E
Sbjct: 375 TSYKPQHP--YKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEFFTTE 428
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 203 bits (517), Expect = 2e-52
Identities = 116/296 (39%), Positives = 173/296 (58%), Gaps = 16/296 (5%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
T Y ++ +G G YGVV +V+ N VA+KKI E+ +RE+ LL+ L+
Sbjct: 30 TKYMPIKPIGRGAYGVVCSSVN-SDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRH 88
Query: 65 DNIVRLYDI---VHSDAHK-LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
+N++ L D+ +H + K +YLV+E +D DL + ++S Q L + + F+ QL +G
Sbjct: 89 ENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKS---SQVLSNDHCQYFLFQLLRG 145
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
+ Y H+ I+HRDLKP NLL+N + +LK+ DFGLARA + T +VT WYRAPE+L
Sbjct: 146 LKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTKGQFMTEYVVTRWYRAPELL 205
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
L Y T +DVWS+GCIFAE+ RKP+F G ++Q+ I +LG+ E D+ ++
Sbjct: 206 LCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQREE---DLEFID 262
Query: 241 DFKT-----TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ K + P +LS + P IDLL K++ +DP RIS A+QHPY
Sbjct: 263 NPKAKRYIRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKRISVSEALQHPY 318
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 203 bits (516), Expect = 3e-52
Identities = 111/292 (38%), Positives = 169/292 (57%), Gaps = 10/292 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y + +KVGEGTY VVY R +A+K+I+ +G+ +AIRE+ L+E++ N
Sbjct: 7 YTKEKKVGEGTYAVVYLGCQ-HSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPN 65
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPL--GGNIIKKFMMQLCKGIAYC 124
++ L DI + L LV EFL DL E + KD+ + IK +M+ +G+ +C
Sbjct: 66 VIELIDIFMA-YDNLNLVLEFLPTDL----EVVIKDKSILFTPADIKAWMLMTLRGVYHC 120
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H + I+HRDLKP NLL + DG +K+ DFGLARA P T +VT WYRAPE+L G K
Sbjct: 121 HRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAK 180
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK- 243
Y++ +D+WS+G IFAE+ R P G +++DQ+ FR LGTP +R WP++ +
Sbjct: 181 HYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNK 240
Query: 244 -TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+P +R L + + +D + ++T +P R +A + ++ YFKE
Sbjct: 241 LQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKE 292
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 202 bits (515), Expect = 4e-52
Identities = 114/324 (35%), Positives = 178/324 (54%), Gaps = 41/324 (12%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLR-HQNRVVAMKKIRLES-------EDEGVPSTAIREISL 58
YK + + GTYG VYKAV + R+ A+KK + ES + GV +AIRE+ L
Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMML 64
Query: 59 LKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKR--YMESIPKDQPLGGNIIKKFMMQ 116
+E++ +NIV L ++ D + +VFE+ + DL + + S + + + +I+K + Q
Sbjct: 65 CREIQHENIVSLVQVLLKDG-TISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQ 123
Query: 117 LCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHE---IVTLW 173
+ G+AY H + I+HRDLKP N++I G +K+GD GL R P+ + +VT+W
Sbjct: 124 IINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTIW 183
Query: 174 YRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDS-----------EIDQIFKIF 222
YRAPE+LLG Y+ +DVW+IGCI+ EM PLF GD + Q+ +I
Sbjct: 184 YRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQSTQMLRIM 243
Query: 223 RVLGTPNERTWPDIIYLPDF-----------KTTFPKWNRRNLSEVIPSLDANGIDLLDK 271
+LGTP E WP + P++ P+W + + + D G+DLL K
Sbjct: 244 ELLGTPTEERWPGLKNYPEYYQLSSFEVRYWNNLLPQW-----YQTVKNRDPQGLDLLMK 298
Query: 272 LITYDPIHRISAKRAVQHPYFKEE 295
++ YDP RI+AK+A++H +F +
Sbjct: 299 MLQYDPKSRITAKQALEHVFFTSD 322
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 202 bits (514), Expect = 5e-52
Identities = 115/298 (38%), Positives = 175/298 (58%), Gaps = 15/298 (5%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
T Y++LEK+G+GTY VYKA DL ++VA+KK+R ++ + REI +L+ L
Sbjct: 112 TTYEKLEKIGQGTYSNVYKAKDLL-SGKIVALKKVRFDNLEAESVKFMAREILVLRRLNH 170
Query: 65 DNIVRLYDIVHSDAH-KLYLVFEFLDLDLKRYM--ESIPKDQPLGGNIIKKFMMQLCKGI 121
N+++L +V S LYLVFE+++ DL + + D P +K FM QL G+
Sbjct: 171 PNVIKLQGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQ----VKCFMKQLLSGL 226
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLR-AYTHEIVTLWYRAPEVL 180
+CH+ ++HRD+K NLLI+ DG LK+ DFGLA + + T +VTLWYR PE+L
Sbjct: 227 EHCHSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSRVVTLWYRPPELL 286
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
LG Y TGVD+WS GCI AE+ KP+ G +E++Q+ KIF++ G+P++ W LP
Sbjct: 287 LGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKK-YRLP 345
Query: 241 D---FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+ FK P +R ++E + + L++ L+T DP R ++ A+ +F E
Sbjct: 346 NATLFKPQHP--YKRCVAEAFNGFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTE 401
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 202 bits (513), Expect = 6e-52
Identities = 114/283 (40%), Positives = 173/283 (60%), Gaps = 8/283 (2%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
+ YK LEK+GEG +G V+KA+DL+ +N+ VA+KK+ L+++ + +REI L+ K
Sbjct: 7 SRYKMLEKIGEGVHGCVFKAIDLQ-RNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKS 65
Query: 65 DNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
+ I+ + DI + D L LV E+ L ++S + PL ++KF Q+ KGIAY
Sbjct: 66 EYILDIIDI-YPDLTGLSLVLEYQPDTLYNRLKS--EVNPLSRQQVRKFAHQMFKGIAYL 122
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP--LRAYTHEIVTLWYRAPEVLLG 182
H ++HRD+KP NLLI+ LK+ DFGLAR + R Y+ ++ T WYRAPE+L G
Sbjct: 123 HEAGLMHRDIKPANLLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFG 182
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
++Y TGVD+W+ GC+ AEM PLF+G ++I+Q+ I R LG+P WP++ LPD+
Sbjct: 183 SQKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLPDY 242
Query: 243 -KTTFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISA 283
K FP + + PS A I+L+ L+ Y+P +R+ A
Sbjct: 243 SKIRFPNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKNRLKA 285
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 201 bits (511), Expect = 1e-51
Identities = 117/297 (39%), Positives = 173/297 (57%), Gaps = 18/297 (6%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
T Y ++ +G G YGVV +V+ R N VA+KKI E+ +RE+ LL+ L+
Sbjct: 30 TKYVPIKPIGRGAYGVVCSSVN-RESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRH 88
Query: 65 DNIVRLYDIVHSDAHK-----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
+N+V L D++ ++ HK +YLV+E +D DL + ++S Q L + + F+ QL +
Sbjct: 89 ENVVALKDVMMAN-HKRSFKDVYLVYELMDTDLHQIIKS---SQVLSNDHCQYFLFQLLR 144
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 179
G+ Y H+ I+HRDLKP NLL+N + +LK+ DFGLAR + T +VT WYRAPE+
Sbjct: 145 GLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQFMTEYVVTRWYRAPEL 204
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
LL Y T +DVWS+GCIFAE+ RKP+F G ++QI I +LG+ E D+ ++
Sbjct: 205 LLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREE---DLEFI 261
Query: 240 PDFKT-----TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ K + P + S + P + IDLL K++ DP RIS A+QHPY
Sbjct: 262 DNPKAKRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEALQHPY 318
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 201 bits (510), Expect = 1e-51
Identities = 113/298 (37%), Positives = 166/298 (54%), Gaps = 18/298 (6%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y+ L VGEG+YG+V K + + R+VA+KK +D+ V A+REI LLK+L+
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRN-KDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLR 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
+N+V L ++ + YLVFEF+D + +E P L +++K++ Q+ GI +
Sbjct: 60 HENLVNLLEVCKKKK-RWYLVFEFVDHTILDDLELFPNG--LDYQVVQKYLFQIINGIGF 116
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH+H IIHRD+KP+N+L+++ G +KL DFG AR P YT + T WYRAPE+L+G
Sbjct: 117 CHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGD 176
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP--------NERTWPD 235
+Y VDVW+IGC+ EM +PLF GDS+IDQ++ I LG N+
Sbjct: 177 VKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFA 236
Query: 236 IIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ LP+ K R L P L IDL K + DP R + H +F+
Sbjct: 237 GVRLPEIK------EREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQ 288
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 200 bits (508), Expect = 2e-51
Identities = 106/291 (36%), Positives = 174/291 (59%), Gaps = 15/291 (5%)
Query: 11 EKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK---DDNI 67
+ +G+G YG VY+ L H + A+K+I + S++EG+P + +REI+++K L NI
Sbjct: 106 QALGKGAYGNVYRVRSL-HDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNI 164
Query: 68 VRLYDIVHS-----DAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
+ L + H K+ ++ E D DL ++ +IP+ P K Q+ + +
Sbjct: 165 ISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVP--EQQAKHVTAQIVRALD 222
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
+ H H IIHRDLKPQN+L+NRD +KL DFGL++ + A+T +VTLWYR+PEVLL
Sbjct: 223 FLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYS-NTTAFTTLVVTLWYRSPEVLL- 280
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
Y++ VD+W++GCI +E+ R+PLF G +E +Q+ IF+ +GTP + WP +
Sbjct: 281 QSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSESVIA-- 338
Query: 243 KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ +FP++ NL ++ P + I+ + + + YD R+SA+ A+ HP+ K
Sbjct: 339 RDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPFLK 389
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 200 bits (508), Expect = 2e-51
Identities = 110/292 (37%), Positives = 166/292 (56%), Gaps = 29/292 (9%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDE---GVPSTAIREISLLKELK 63
Y ++ +GEG + VY A DL VA+KKI+L S +E G+ TAIREI LLKE+
Sbjct: 5 YDTIKHLGEGQFANVYLAQDLE-SGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIH 63
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
DNI+ L D++ + LVF+F+D DL+ ++ K+ L IK MQ+ G+ +
Sbjct: 64 HDNIIGLRDVI-GHRTSIQLVFDFMDTDLEHVIKD--KEIILMPAHIKNITMQMLLGLEF 120
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
H H I+HRDLKP NLL+N+ G +VT WYRAPE+L G
Sbjct: 121 LHVHWILHRDLKPNNLLMNKMGR----------------------VVTRWYRAPELLFGA 158
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
+ Y G+D+WS+GCI AE+ R P+F G+S+IDQ+ KIF +LG P TWP++ + +
Sbjct: 159 RSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYV 218
Query: 244 TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
P+ L+ + + +DL+ + T+DPI R++ +++Q YF+ +
Sbjct: 219 IIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQ 270
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 200 bits (508), Expect = 2e-51
Identities = 106/291 (36%), Positives = 174/291 (59%), Gaps = 15/291 (5%)
Query: 11 EKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK---DDNI 67
+ +G+G YG VY+ L H + A+K+I + S++EG+P + +REI+++K L NI
Sbjct: 42 QALGKGAYGNVYRVRSL-HDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNI 100
Query: 68 VRLYDIVHS-----DAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
+ L + H K+ ++ E D DL ++ +IP+ P K Q+ + +
Sbjct: 101 ISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVP--EQQAKHVTAQIVRALD 158
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
+ H H IIHRDLKPQN+L+NRD +KL DFGL++ + A+T +VTLWYR+PEVLL
Sbjct: 159 FLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYS-NTTAFTTLVVTLWYRSPEVLL- 216
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
Y++ VD+W++GCI +E+ R+PLF G +E +Q+ IF+ +GTP + WP +
Sbjct: 217 QSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSESVIA-- 274
Query: 243 KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ +FP++ NL ++ P + I+ + + + YD R+SA+ A+ HP+ K
Sbjct: 275 RDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPFLK 325
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 199 bits (505), Expect = 5e-51
Identities = 109/287 (37%), Positives = 166/287 (56%), Gaps = 10/287 (3%)
Query: 10 LEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 69
+ +G G G+V AVD N VA+KKI ++ +REI LL+ +NIV
Sbjct: 63 IRPIGRGACGIVCSAVD-SETNEKVAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVA 121
Query: 70 LYDIV----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
+ D++ +Y+V E ++ DL R ++S DQ L + FM Q+ +G+ Y H
Sbjct: 122 IRDVILPPQRDSFEDVYIVNELMEFDLYRTLKS---DQELTKDHGMYFMYQILRGLKYIH 178
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ ++HRDLKP NLL++ +LK+ DFGLARA T +VT WYRAPE+LLG
Sbjct: 179 SANVLHRDLKPSNLLLSTQCDLKICDFGLARATPES-NLMTEYVVTRWYRAPELLLGSSD 237
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII-YLPDFKT 244
Y+ +DVWS+GCIF E+ NR+PLF G +++Q+ + ++GTP+E + Y +
Sbjct: 238 YTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSEEELGSLSEYAKRYIR 297
Query: 245 TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
P R++ +E P++ IDL++K++T+DP RIS K A+ HPY
Sbjct: 298 QLPTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEALAHPY 344
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 198 bits (504), Expect = 7e-51
Identities = 111/294 (37%), Positives = 176/294 (59%), Gaps = 9/294 (3%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++++L+K+G+GTY VY+A DL ++VAMKK+R + D REI++L++L
Sbjct: 155 SFEKLDKIGQGTYSSVYRARDLE-TGKMVAMKKVRFVNMDPESVRFMAREINILRKLDHP 213
Query: 66 NIVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
N+++L +V S + LYLVFE+++ DL ++ + IK +M QL G+ +C
Sbjct: 214 NVMKLECLVTSKLSGSLYLVFEYMEHDLSGL--ALRPGVKFTESQIKCYMKQLLSGLEHC 271
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPL-RAYTHEIVTLWYRAPEVLLGG 183
H+ I+HRD+K NLL+N DG LK+GDFGLA + + T +VTLWYRAPE+LLG
Sbjct: 272 HSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQDQPLTSRVVTLWYRAPELLLGA 331
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW--PDIIYLPD 241
+Y G+D+WS+GCI E+ KP+ G +E++Q+ KIF+ G+P++ W +
Sbjct: 332 TEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSDDYWQKTKLPLATS 391
Query: 242 FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
FK P +R L E +L + + L+DKL++ +P R +A + +F E
Sbjct: 392 FKPQQP--YKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTLSSKFFTME 443
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 198 bits (503), Expect = 9e-51
Identities = 107/291 (36%), Positives = 162/291 (54%), Gaps = 26/291 (8%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y L ++GEG +G+V+KA + ++A+KK+ L ++G P+ A+REI L+E++
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVE-TGEIIALKKVALRRLEDGFPNQALREIKALQEME 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
D+ V V L FEF+ DL + + PL +K ++ L KG+A+
Sbjct: 60 DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQR--PLAQAQVKSYLQMLLKGVAF 117
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP-LRAYTHEIVTLWYRAPEVLLG 182
CHA+ I+HRDLKP NLLI+ G LK+ DFGLAR F R YTH++ T
Sbjct: 118 CHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR---------- 167
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
S+GCI E+ N PLF G ++I+Q+ + R+LGTPN + WP++ LPD+
Sbjct: 168 -----------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDY 216
Query: 243 -KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
K +F + L EV+P + +DLL + + Y P RI+A +A+ H YF
Sbjct: 217 NKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 267
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 198 bits (503), Expect = 9e-51
Identities = 113/296 (38%), Positives = 171/296 (57%), Gaps = 16/296 (5%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
T Y ++ +G G YGVV +++ R N VA+KKI E+ +RE+ LL+ ++
Sbjct: 30 TKYVPIKPIGRGAYGVVCSSIN-RETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRH 88
Query: 65 DNIVRLYDIV----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
+N++ L D++ S +YLV+E +D DL + ++S Q L + K F+ QL +G
Sbjct: 89 ENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKS---SQSLSDDHCKYFLFQLLRG 145
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
+ Y H+ I+HRDLKP NLL+N + +LK+ DFGLAR + T +VT WYRAPE+L
Sbjct: 146 LKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGNEQFMTEYVVTRWYRAPELL 205
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
L Y T +DVWS+GCIFAE+ RKP+F G ++Q+ I V+G+ E DI ++
Sbjct: 206 LCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQE---SDIRFID 262
Query: 241 D-----FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ F + P +LS + P + IDLL +++ +DP RIS A+ HPY
Sbjct: 263 NPKARRFIKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDALLHPY 318
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 195 bits (495), Expect = 7e-50
Identities = 109/298 (36%), Positives = 174/298 (57%), Gaps = 18/298 (6%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGV-PSTAIREISLLKEL 62
+ Y+++ K+GEG+YGVV+K + R ++VA+KK LESED+ V A+REI +LK+L
Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRN-RDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQL 59
Query: 63 KDDNIVRLYDIVHSDAHKLYLVFEFLDL----DLKRYMESIPKDQPLGGNIIKKFMMQLC 118
K N+V L ++ +L+LVFE+ D +L RY +P+ +++K Q
Sbjct: 60 KHPNLVNLLEVFRRK-RRLHLVFEYCDHTVLHELDRYQRGVPE------HLVKSITWQTL 112
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+ + +CH H IHRD+KP+N+LI + +KL DFG AR P YT + T WYR+PE
Sbjct: 113 QAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPE 172
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLG---TPNERTWPD 235
+L+G QY VDVW+IGC+FAE+ + PL+ G S++DQ++ I + LG +++ +
Sbjct: 173 LLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFST 232
Query: 236 IIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
Y K P+ + L P++ + LL + DP R++ ++ + HPYF+
Sbjct: 233 NQYFSGVKIPDPE-DMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFE 289
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 194 bits (492), Expect = 2e-49
Identities = 102/224 (45%), Positives = 148/224 (65%), Gaps = 9/224 (4%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+T Y +G GTYG VY+A+D + +V A+K+IRL +E EG+P TA+REIS+LK+L
Sbjct: 1 MTRYILGALIGSGTYGEVYEAIDTETKEKV-ALKRIRL-NEKEGMPGTALREISILKKLS 58
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
NI+ L I+H+DA L +VF F+D +LK+Y+ G NI++ +C G+ Y
Sbjct: 59 HRNIISLVSIIHTDA-LLTMVFPFIDYELKKYI-----GMNTGKNIMELVNQLIC-GVHY 111
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
H ++HRDLKPQN+L+ DG LK+ DFGL+R+ + + Y+ E+VTLWYR+PE+L+G
Sbjct: 112 LHRMNVVHRDLKPQNILVTSDGVLKIADFGLSRSLEIRVPPYSSEVVTLWYRSPELLMGS 171
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGT 227
Y VD+WS+GCI EM +PLF G+S+ +Q+ I R GT
Sbjct: 172 TSYRFYVDIWSLGCIIYEMITLEPLFPGESKENQLTLIRRKAGT 215
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 194 bits (492), Expect = 2e-49
Identities = 113/296 (38%), Positives = 175/296 (58%), Gaps = 13/296 (4%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++++L+K+G+GTY VYKA DL ++VAMKK+R + D REI +L++L
Sbjct: 146 SFEKLDKIGQGTYSSVYKARDLE-TGKIVAMKKVRFVNMDPESVRFMAREILILRKLDHP 204
Query: 66 NIVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMES--IPKDQPLGGNIIKKFMMQLCKGIA 122
N+++L +V S + LYLVFE+++ DL + I +P IK +M QL +G+
Sbjct: 205 NVMKLEGLVTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQ----IKCYMQQLFRGLE 260
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF-GVPLRAYTHEIVTLWYRAPEVLL 181
+CH I+HRD+K NLLIN +G LK+GDFGLA + G T +VTLWYRAPE+LL
Sbjct: 261 HCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYRGDGDLQLTSRVVTLWYRAPELLL 320
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW--PDIIYL 239
G +Y +D+WS GCI E+ KP+ G +E++Q+ KIF++ G+P+E W +
Sbjct: 321 GATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDYWRRATLPLA 380
Query: 240 PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
FK + P + L+E ++ + L++KL+ +P R SA ++ +F E
Sbjct: 381 TSFKPSHP--YKPVLAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFFTTE 434
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 194 bits (492), Expect = 2e-49
Identities = 113/296 (38%), Positives = 177/296 (59%), Gaps = 19/296 (6%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++++LEK+G+GTY VYKA DL N++VA+KK+R + D REI +L+ L
Sbjct: 162 SFEKLEKIGQGTYSSVYKARDLE-TNQLVALKKVRFANMDPDSVRFMAREIIILRRLDHP 220
Query: 66 NIVRLYDIVHSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNI----IKKFMMQLCKG 120
N+++L ++ S +YL+FE+++ DL + S P G N IK +M QL G
Sbjct: 221 NVMKLEGLITSRVSGSMYLIFEYMEHDLAG-LASTP-----GINFSEAQIKCYMKQLLHG 274
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF-GVPLRAYTHEIVTLWYRAPEV 179
+ +CH+ ++HRD+K NLL++ + NLK+GDFGLA + G + T +VTLWYR PE+
Sbjct: 275 LEHCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQGHQKQPLTSRVVTLWYRPPEL 334
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
LLG Y VD+WS GCI AE+ KP+ G +E++Q+ KIF++ G+P+E W I L
Sbjct: 335 LLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEEYW-KISKL 393
Query: 240 PD---FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
P FK P +R ++E SL ++ + L++ L+ +P R + A++ +F
Sbjct: 394 PHATIFKPQQP--YKRCVAETFKSLPSSALALVEVLLAVEPDARGTTASALESEFF 447
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 192 bits (488), Expect = 5e-49
Identities = 110/296 (37%), Positives = 175/296 (58%), Gaps = 17/296 (5%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLE--SEDEGVPSTAIREISLLKE 61
+ Y + ++G+GTYG V +VA+K+++ + S DE + +RE+ LK+
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKS-NESGELVAIKRMKRKFYSWDECMN---LREVKSLKK 56
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L N+++L +++ + H LY +FE++ +L + M+ K P ++I+ M Q+ +G+
Sbjct: 57 LNHANVIKLKEVIRENDH-LYFIFEYMKENLYQLMKDRNKLFP--ESVIRNIMYQILQGL 113
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA---YTHEIVTLWYRAPE 178
A+ H H HRD+KP+NLL +K+ DFGLAR LR+ YT + T WYRAPE
Sbjct: 114 AFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARE----LRSQPPYTDYVSTRWYRAPE 169
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
VLL YS+ +DVW++G I AE+ +PLF G SE+D+IFKI +VLGTP + WP+
Sbjct: 170 VLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQ 229
Query: 239 L-PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
L FP+ NL +IP+ I L+ +++ +DP R +A +A++HPYF+
Sbjct: 230 LASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 192 bits (487), Expect = 6e-49
Identities = 110/292 (37%), Positives = 183/292 (62%), Gaps = 12/292 (4%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESE--DEGVPSTAIREISLLKE 61
+ YK LE++G+GT G VYKAV+L VVA+KK++ + +E V +RE+ L++
Sbjct: 9 MCRYKILEELGDGTCGSVYKAVNLETYE-VVAVKKMKRKFYYWEECVN---LREVKALRK 64
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L +I++L +IV + ++L+ +FE +D +L M+ +++P I+ FM Q+ +G+
Sbjct: 65 LNHPHIIKLKEIVR-EHNELFFIFECMDHNLYHIMKE--RERPFSEGEIRSFMSQMLQGL 121
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
A+ H + HRDLKP+NLL+ + LK+ DFGLAR + YT + T WYRAPEVLL
Sbjct: 122 AHMHKNGYFHRDLKPENLLVTNN-ILKIADFGLAREVA-SMPPYTEYVSTRWYRAPEVLL 179
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
Y+ VD+W++G I AE+ PLF G+SEIDQ++KI VLG P+ T+P+ +
Sbjct: 180 QSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISR 239
Query: 242 FKT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+ + ++ + +++++P+ IDL+++L ++DP+ R +A A+ HP+F
Sbjct: 240 IMSISHTEFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFF 291
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 191 bits (486), Expect = 8e-49
Identities = 117/319 (36%), Positives = 178/319 (55%), Gaps = 41/319 (12%)
Query: 12 KVGEGTYGVVYKAVDLRHQN-RVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRL 70
KVG GTYG VYKA ++ + A+K+I E G+ +A REI+LL+ELK N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 71 YDIVHSDA-HKLYLVFEFLDLDL------KRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
+ S A K++L+F++ + DL R ++ K L ++K + Q+ GI Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 124 CHAHRIIHRDLKPQNLLINRDG----NLKLGDFGLARAFGVPLRAYTH---EIVTLWYRA 176
HA+ ++HRDLKP N+L+ +G +K+ D G AR F PL+ +VT WYRA
Sbjct: 142 LHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRA 201
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLF---------SGDSEIDQIFKIFRVLGT 227
PE+LLG + Y+ +D+W+IGCIFAE+ +P+F S DQ+ +IF V+G
Sbjct: 202 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGF 261
Query: 228 PNERTWPDIIYLPDFKTTFPKWNRRNLS-----------EVIPSLDANGIDLLDKLITYD 276
P ++ W DI +P+ T + R + +V P D+ LL KL+T D
Sbjct: 262 PADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMD 319
Query: 277 PIHRISAKRAVQHPYFKEE 295
PI RI++++A+Q PYF E+
Sbjct: 320 PIKRITSEQAMQDPYFLED 338
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 191 bits (485), Expect = 1e-48
Identities = 109/298 (36%), Positives = 172/298 (57%), Gaps = 19/298 (6%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
T Y ++ +G G YGVV +++ RV A+KKI E+ +RE+ LL+ ++
Sbjct: 30 TKYVPIKPIGRGAYGVVCSSINSETNERV-AIKKIHNVFENRIDALRTLRELKLLRHVRH 88
Query: 65 DNIVRLYDIV----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
+N++ L D++ +YLV+E +D DL + ++S Q L + K F+ QL +G
Sbjct: 89 ENVISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIKS---SQSLSDDHCKYFLFQLLRG 145
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
+ Y H+ I+HRDLKP NLL+N + +LK+ DFGLAR + + Y +VT WYRAPE+L
Sbjct: 146 LKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTYEQFMTEY---VVTRWYRAPELL 202
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
L Y T +DVWS+GCIFAE+ RKP+F G ++Q+ I V+G +++ W D+ ++
Sbjct: 203 LCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVG--SQQDW-DLQFID 259
Query: 241 D-----FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ F + P + S + P + IDLL +++ +DP RIS A+ HPY +
Sbjct: 260 NQKARRFIKSLPFSKGTHFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDALLHPYME 317
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 191 bits (485), Expect = 1e-48
Identities = 110/302 (36%), Positives = 177/302 (58%), Gaps = 22/302 (7%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
+++++ E++G GT+ V+KA DL +N+ VA+K+IR + + REI +L++L
Sbjct: 101 SHFEKQEQIGGGTFSKVFKARDLL-RNKTVALKRIRFDINNSESIKCIAREIIILRKLDH 159
Query: 65 DNIVRLYDI--VHSDAHKLYLVFEFLDLDLKRYME--SIPKDQPLGGNIIKKFMMQLCKG 120
N+++L + V D+ LYL+FE+++ DL + +P +K +M QL +G
Sbjct: 160 PNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLGLSSLLGVHFSEPQ----VKCYMRQLLRG 215
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF----GVPLRAYTHEIVTLWYRA 176
+ +CH + ++HRD+K NLLIN DG LK+ DFGLA F VPL T + TLWYR
Sbjct: 216 LDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLATFFDPHNSVPL---TTHVATLWYRP 272
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE+LLG Y GVD+WS GC+ E+ KP+ G +E DQ+ KIF++ G+P++ W +
Sbjct: 273 PELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSDDYWTKL 332
Query: 237 ---IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ P + +P + +++E A+ I LL+ L++ DP R +A A++ YFK
Sbjct: 333 KLQLSTP-LRPIYPYGS--HIAETFKQFPASVISLLETLLSIDPDFRGTAASALKSKYFK 389
Query: 294 EE 295
E
Sbjct: 390 TE 391
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 191 bits (484), Expect = 1e-48
Identities = 116/318 (36%), Positives = 182/318 (56%), Gaps = 39/318 (12%)
Query: 12 KVGEGTYGVVYKAVDLRHQN-RVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRL 70
KVG GTYG VYKA ++ + A+K+I E G+ +A REI+LL+ELK N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 71 YDIV--HSDAHKLYLVFEFLDLDL------KRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
+ HSD K++L+F++ + DL R ++ K L +++K + Q+ GI
Sbjct: 82 QKVFLSHSD-RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIH 140
Query: 123 YCHAHRIIHRDLKPQNLLINRDG----NLKLGDFGLARAFGVPLRAYTH---EIVTLWYR 175
Y HA+ ++HRDLKP N+L+ +G +K+ D G AR F PL+ +VT WYR
Sbjct: 141 YLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYR 200
Query: 176 APEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLF---------SGDSEIDQIFKIFRVLG 226
APE+LLG + Y+ +D+W+IGCIFAE+ +P+F S DQ+ +IF V+G
Sbjct: 201 APELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMG 260
Query: 227 TPNERTWPDIIYLPDFKTTFPKWNRRNL--SEVIPSLDANGID-------LLDKLITYDP 277
P ++ W DI +P++ T + R S +I ++ + + LL KL+T DP
Sbjct: 261 FPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDP 320
Query: 278 IHRISAKRAVQHPYFKEE 295
RI++++A+Q PYF+E+
Sbjct: 321 TKRITSEQALQDPYFQED 338
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 191 bits (484), Expect = 1e-48
Identities = 102/287 (35%), Positives = 171/287 (59%), Gaps = 16/287 (5%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+G+G YG+V A++ N VA+KKI +++ +REI LL+ + +NIV + D
Sbjct: 69 IGKGAYGIVCSAMN-SETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRD 127
Query: 73 IV----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHR 128
I+ + + +Y+ +E +D DL + + S +Q L + F+ Q+ +G+ Y H+
Sbjct: 128 IIPPPLRNAFNDVYIAYELMDTDLHQIIRS---NQALSEEHCQYFLYQILRGLKYIHSAN 184
Query: 129 IIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYST 188
++HRDLKP NLL+N + +LK+ DFGLAR T +VT WYRAPE+LL Y+
Sbjct: 185 VLHRDLKPSNLLLNANCDLKICDFGLARVTSES-DFMTEYVVTRWYRAPELLLNSSDYTA 243
Query: 189 GVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD----FKT 244
+DVWS+GCIF E+ +RKPLF G + Q+ + ++GTP+E ++ +L + +
Sbjct: 244 AIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEE---ELEFLNENAKRYIR 300
Query: 245 TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
P + R+++++ P++ IDL++K++T+DP RI+ A+ HPY
Sbjct: 301 QLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHPY 347
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 190 bits (482), Expect = 2e-48
Identities = 115/298 (38%), Positives = 169/298 (56%), Gaps = 13/298 (4%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQ--NRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
+ ++ L VGEG YGVV K RH+ + +VA+KK + E+E V T +RE+ +L+
Sbjct: 10 MNKFEILGVVGEGAYGVVLKC---RHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRT 66
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
LK +NIV L + KLYLVFE+++ ++ +E +P P +K ++ QL K I
Sbjct: 67 LKQENIVELKEAFRRRG-KLYLVFEYVEKNMLELLEEMPNGVP--PEKVKSYIYQLIKAI 123
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-YTHEIVTLWYRAPEVL 180
+CH + I+HRD+KP+NLLI+ + LKL DFG AR A YT + T WYR+PE+L
Sbjct: 124 HWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELL 183
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
LG Y VD+WS+GCI E+ + +PLF G+SEIDQ+F I +VLG P
Sbjct: 184 LGA-PYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNP 242
Query: 241 DFK-TTFPKWNRRNLSE--VIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
F FP N E + L++ +DL+ L+ DP R ++ + HP F+ +
Sbjct: 243 RFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ 300
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 189 bits (481), Expect = 3e-48
Identities = 108/293 (36%), Positives = 172/293 (57%), Gaps = 11/293 (3%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLE--SEDEGVPSTAIREISLLKE 61
+ Y + ++G+GTYG V + ++A+KK++ + S +E + +RE+ LK+
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIE-SGELIAIKKMKRKFYSWEECMN---LREVKSLKK 56
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L N+V+L +++ + H LY +FE++ +L + ++ K P + I+ M Q+ +G+
Sbjct: 57 LNHANVVKLKEVIRENDH-LYFIFEYMKENLYQLIKERNKLFP--ESAIRNIMYQILQGL 113
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
A+ H H HRDLKP+NLL +K+ DFGLAR YT + T WYRAPEVLL
Sbjct: 114 AFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLL 172
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
YS+ +DVW++GCI AE+ +PLF G SEID IFKI +VLGTP + WP+ L
Sbjct: 173 RSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSS 232
Query: 242 -FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+P+ NL +IP+ + + LL ++ +DP R +A +A+++PYF+
Sbjct: 233 AMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 189 bits (481), Expect = 3e-48
Identities = 103/291 (35%), Positives = 168/291 (57%), Gaps = 17/291 (5%)
Query: 10 LEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 69
L +G G YG+V A + VA+KKI ++ +REI LLK + +N++
Sbjct: 46 LRPIGRGAYGIVCAATN-SETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIA 104
Query: 70 LYDIV----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
+ DI+ + + +Y+V+E +D DL + + S +QPL + + F+ QL +G+ Y H
Sbjct: 105 VKDIIKPPQRENFNDVYIVYELMDTDLHQIIRS---NQPLTDDHCRFFLYQLLRGLKYVH 161
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ ++HRDLKP NLL+N + +LKLGDFGLAR T +VT WYRAPE+LL +
Sbjct: 162 SANVLHRDLKPSNLLLNANCDLKLGDFGLARTKS-ETDFMTEYVVTRWYRAPELLLNCSE 220
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD---- 241
Y+ +D+WS+GCI E R+PLF G + Q+ I ++G+P++ + + +L
Sbjct: 221 YTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSS---LGFLRSDNAR 277
Query: 242 -FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ P++ R+N + P++ A +DLL+K++ +DP RI+ A+ HPY
Sbjct: 278 RYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITVDEALCHPY 328
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 189 bits (481), Expect = 3e-48
Identities = 108/286 (37%), Positives = 163/286 (56%), Gaps = 13/286 (4%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+G G YG+V +D N +VAMKKI ++ +REI LL+ L +NI+ + D
Sbjct: 44 IGRGAYGIVCSVLDTE-TNELVAMKKIANAFDNHMDAKRTLREIKLLRHLDHENIIAIRD 102
Query: 73 IVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHR 128
+V + +Y+ E +D DL + + S +Q L + F+ QL +G+ Y H+
Sbjct: 103 VVPPPLRRQFSDVYISTELMDTDLHQIIRS---NQSLSEEHCQYFLYQLLRGLKYIHSAN 159
Query: 129 IIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYST 188
IIHRDLKP NLL+N + +LK+ DFGLAR T +VT WYRAPE+LL Y+
Sbjct: 160 IIHRDLKPSNLLLNANCDLKICDFGLARPTSEN-DFMTEYVVTRWYRAPELLLNSSDYTA 218
Query: 189 GVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK---TT 245
+DVWS+GCIF E+ NRKPLF G + Q+ + +LGTP E + D K
Sbjct: 219 AIDVWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDL-GFTHNEDAKRYIRQ 277
Query: 246 FPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
P + R+ L+++ ++ IDL+D+++T+DP RI+ ++A+ H Y
Sbjct: 278 LPNFPRQPLAKLFSHVNPMAIDLVDRMLTFDPNRRITVEQALNHQY 323
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 189 bits (481), Expect = 3e-48
Identities = 108/292 (36%), Positives = 171/292 (57%), Gaps = 11/292 (3%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLE--SEDEGVPSTAIREISLLKE 61
+ Y L ++G+GTYG V + VA+K+++ + S +E + +RE+ LK+
Sbjct: 1 MNRYITLTQLGDGTYGTVVLG-QRKDTGEKVAIKRMKRKYYSWEEAMN---LREVKSLKK 56
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L NIV+L +++ + LY VFE++ +L + ++ +D L +K + Q+ G+
Sbjct: 57 LSHPNIVKLKEVIREN-DTLYFVFEYMKENLYQMIKD--RDTHLPEPELKSILFQVLTGL 113
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
A+ H H HRDLKP+NLL + +K+ DFGLAR +T + T WYRAPEVLL
Sbjct: 114 AFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLAREIR-SRPPFTDYVSTRWYRAPEVLL 172
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
Y + +D+W++GCI AE+ +PLF G SE+DQ+FKI VLGTP++ WPD L
Sbjct: 173 HSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLAS 232
Query: 242 -FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+P + LS V+ NG+DLL+ ++ YDP R +A++++++PYF
Sbjct: 233 MIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF 284
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 189 bits (480), Expect = 4e-48
Identities = 108/291 (37%), Positives = 172/291 (58%), Gaps = 15/291 (5%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++++LE +G+GTY VY+A DL N++VA+KK+R + D REI +L+ L
Sbjct: 145 SFEKLEMIGQGTYSSVYRARDLE-TNQIVALKKVRFANMDPESVRFMAREIIILRRLNHP 203
Query: 66 NIVRLYDIVHSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
N+++L ++ S A +YL+FE++D DL + S P I QL G+ +C
Sbjct: 204 NVMKLEGLIISKASGSMYLIFEYMDHDLAG-LASTP-------GIKFSQAQQLLLGLEHC 255
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF-GVPLRAYTHEIVTLWYRAPEVLLGG 183
H+ ++HRD+K NLL++R+ NLK+GDFGL+ + G + T +VTLWYR PE+LLG
Sbjct: 256 HSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRKQPLTSRVVTLWYRPPELLLGS 315
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW--PDIIYLPD 241
Y VD+WS GCI AE+ KPL G +E++Q+ KIF++ G+P+E W + +
Sbjct: 316 TDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWRRSRLRHATI 375
Query: 242 FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
FK P +R +++ L ++ + LL+ L+ +P R +A A+Q +F
Sbjct: 376 FKPQHP--YKRCVADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEFF 424
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 189 bits (479), Expect = 5e-48
Identities = 105/297 (35%), Positives = 172/297 (57%), Gaps = 15/297 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y L +GEG YG+V A D ++ RV A+KKI E + +REI +L + +N
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRV-AIKKIS-PFEHQTYCQRTLREIKILLRFRHEN 82
Query: 67 IVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
I+ + DI+ + + +Y+V + ++ DL + + K Q L + I F+ Q+ +G+
Sbjct: 83 IIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL----KTQHLSNDHICYFLYQILRGLK 138
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP---LRAYTHEIVTLWYRAPEV 179
Y H+ ++HRDLKP NLL+N +LK+ DFGLAR T + T WYRAPE+
Sbjct: 139 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEI 198
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
+L K Y+ +D+WS+GCI AEM + +P+F G +DQ+ I +LG+P++ II L
Sbjct: 199 MLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINL 258
Query: 240 P--DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
++ + P N+ + + P+ D+ +DLLDK++T++P RI ++A+ HPY ++
Sbjct: 259 KARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 189 bits (479), Expect = 5e-48
Identities = 105/297 (35%), Positives = 172/297 (57%), Gaps = 15/297 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y L +GEG YG+V A D ++ RV A+KKI E + +REI +L + +N
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRV-AIKKIS-PFEHQTYCQRTLREIKILLRFRHEN 82
Query: 67 IVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
I+ + DI+ + + +Y+V + ++ DL + + K Q L + I F+ Q+ +G+
Sbjct: 83 IIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL----KTQHLSNDHICYFLYQILRGLK 138
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP---LRAYTHEIVTLWYRAPEV 179
Y H+ ++HRDLKP NLL+N +LK+ DFGLAR T + T WYRAPE+
Sbjct: 139 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEI 198
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
+L K Y+ +D+WS+GCI AEM + +P+F G +DQ+ I +LG+P++ II L
Sbjct: 199 MLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPSQEDLNCIINL 258
Query: 240 P--DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
++ + P N+ + + P+ D+ +DLLDK++T++P RI ++A+ HPY ++
Sbjct: 259 KARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 315
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 189 bits (479), Expect = 5e-48
Identities = 112/302 (37%), Positives = 166/302 (54%), Gaps = 22/302 (7%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y++L ++GEG+YGVVYK D R +VA+K+ +D + A+REI LLK LK
Sbjct: 1 MDRYEKLSRLGEGSYGVVYKCRD-RETGALVAVKRFVESEDDPAIRKIALREIRLLKNLK 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
N+V L ++ +L+LVFEF +L + +E P+ P ++ K+ Q G+AY
Sbjct: 60 HPNLVSLLEVFRRK-RRLHLVFEFCELTVLHELERHPQGCP--EHLTKQICYQTLLGVAY 116
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH +HRD+KP+N+L+ G +KL DFG AR P YT + T WYRAPE+L+G
Sbjct: 117 CHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGD 175
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP--------NERTWPD 235
QY T VDVW+IGC+FAE+ + L+ G S++DQ++ I + LG + +
Sbjct: 176 TQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFK 235
Query: 236 IIYLPDFKTTFPKWNRRNLSEVIPSLDANG---IDLLDKLITYDPIHRISAKRAVQHPYF 292
I LP T P L + +P+ ID L K + DP R S ++ +H YF
Sbjct: 236 GITLPVPPTLEP------LEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF 289
Query: 293 KE 294
+
Sbjct: 290 DD 291
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 188 bits (478), Expect = 7e-48
Identities = 111/292 (38%), Positives = 172/292 (58%), Gaps = 11/292 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLES-EDEGVPSTAIREISLLKELKDD 65
+++LEK+G+GTY V++AV+ R+VA+KK+R ++ E E V A REI +L+ L
Sbjct: 121 FEKLEKIGQGTYSNVFRAVETE-TGRIVALKKVRFDNFEPESVKFMA-REILILRRLNHP 178
Query: 66 NIVRLYDIVHSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
NI++L ++ S + LVFE+++ DL + S D IK +M QL G+ +C
Sbjct: 179 NIIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSS--PDIKFTTPQIKCYMKQLLSGLDHC 236
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR---AFGVPLRAYTHEIVTLWYRAPEVLL 181
H+ ++HRD+K NLL++ +G LK+ DFGLA + G + T +VTLWYR PE+LL
Sbjct: 237 HSRGVMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTSRVVTLWYRPPELLL 296
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
G Y VD+WS+GC+FAE+ KP+ G +E++Q+ KIF++ G+P E W LP
Sbjct: 297 GATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDYWKK-SKLPH 355
Query: 242 FKTTFPKWNRRN-LSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
P+ + L E + L I+L++ L++ DP R +A A+ YF
Sbjct: 356 AMLFKPQQTYDSCLRETLKDLSETEINLIETLLSIDPHKRGTASSALVSQYF 407
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 188 bits (478), Expect = 7e-48
Identities = 109/294 (37%), Positives = 172/294 (58%), Gaps = 11/294 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLES-EDEGVPSTAIREISLLKELKDD 65
+++++K+G+GTY VYKA D+ ++VA+KK+R ++ E E V A REI +L+ L
Sbjct: 118 FEKIDKIGQGTYSNVYKAKDML-TGKIVALKKVRFDNLEPESVKFMA-REILVLRRLDHP 175
Query: 66 NIVRLYDIVHSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
N+V+L +V S LYLVF+++D DL S + +K M QL G+ +C
Sbjct: 176 NVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASS--PVVKFSESEVKCLMRQLISGLEHC 233
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP-LRAYTHEIVTLWYRAPEVLLGG 183
H+ ++HRD+K NLLI+ G LK+ DFGLA F R T +VTLWYRAPE+LLG
Sbjct: 234 HSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPELLLGA 293
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWP--DIIYLPD 241
Y G+D+WS GCI AE+ +P+ G +E++Q+ KI+++ G+P+E W +
Sbjct: 294 TDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAI 353
Query: 242 FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+K P +R++ E + + L+D L++ +P R +A A++ +F E
Sbjct: 354 YKPREP--YKRSIRETFKDFPPSSLPLIDALLSIEPEDRQTASAALKSEFFTSE 405
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 188 bits (477), Expect = 9e-48
Identities = 102/289 (35%), Positives = 164/289 (56%), Gaps = 10/289 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+++ +GEGT+G V A R A+KK+ E EG+ T IRE+ +L+ + +
Sbjct: 22 YEKIRIIGEGTFGQVILA---RKGRARYALKKV--SKEKEGLSVTTIREVQVLRAMGHPS 76
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHA 126
IVRL ++V +Y+VF + DL R++ S + + IK Q+ +G+ Y H+
Sbjct: 77 IVRLIEVVVEPGGDIYMVFPYFPYDLNRFIRS----NKMTCSEIKHIFYQIAQGVCYIHS 132
Query: 127 HRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQY 186
I+HRDLK N+L+++ N + DFG+AR + AYT +VTLWYRAPE+LLG Y
Sbjct: 133 KGIMHRDLKSANILLDQKLNASIADFGMAR-YTTKTGAYTPGMVTLWYRAPEILLGSSSY 191
Query: 187 STGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTTF 246
+ VD+WS+GCI EM +F G +E+ Q+ + G+ NE ++P + LP F+
Sbjct: 192 TYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGSINENSYPGVQDLPGFRNFR 251
Query: 247 PKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
+ R + +I DA+ ++L+ K++ DP RI+ ++ V YF+ E
Sbjct: 252 LPQSPRRIEGIIRKHDASAVELVSKMLCLDPSKRITVEQVVGSKYFEHE 300
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 187 bits (476), Expect = 1e-47
Identities = 110/295 (37%), Positives = 164/295 (55%), Gaps = 17/295 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ L+ VG G YG V AVD R +V A+KK+ + E A RE+ LLK ++ +N
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKV-AIKKLYRPFQSELFAKRAYRELRLLKHMRHEN 85
Query: 67 IVRLYDIVHSDAH-----KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
++ L D+ D YLV F+ DL + M K + LG + I+ + Q+ KG+
Sbjct: 86 VIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM----KHEKLGEDRIQFLVYQMLKGL 141
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y HA IIHRDLKP NL +N D LK+ DFGLAR + Y +VT WYRAPEV+L
Sbjct: 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGY---VVTRWYRAPEVIL 198
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
+Y+ VD+WS+GCI AEM K LF G +DQ+ +I +V GTP + + +
Sbjct: 199 NWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTP-PAEFVQRLQSDE 257
Query: 242 FKTT---FPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
K P+ +++ + ++ + ++LL+K++ D R++A A+ HPYF+
Sbjct: 258 AKNNMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFE 312
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 187 bits (476), Expect = 1e-47
Identities = 103/298 (34%), Positives = 174/298 (57%), Gaps = 17/298 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y +L+ +GEG YG+V A D + RV A+KKI E + +REI +L + +N
Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRV-AIKKIS-PFEHQTYCQRTLREIQILLRFRHEN 99
Query: 67 IVRLYDIVHSDA----HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
++ + DI+ + +Y+V + ++ DL + ++S Q L + I F+ Q+ +G+
Sbjct: 100 VIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKS----QQLSNDHICYFLYQILRGLK 155
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYT----HEIVTLWYRAPE 178
Y H+ ++HRDLKP NLLIN +LK+ DFGLAR P +T + T WYRAPE
Sbjct: 156 YIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPE 214
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
++L K Y+ +D+WS+GCI AEM + +P+F G +DQ+ I +LG+P++ II
Sbjct: 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 274
Query: 239 LP--DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ ++ + P + +++ P D+ +DLLD+++T++P RI+ + A+ HPY ++
Sbjct: 275 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 332
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 187 bits (476), Expect = 1e-47
Identities = 98/264 (37%), Positives = 161/264 (60%), Gaps = 10/264 (3%)
Query: 34 VAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVH----SDAHKLYLVFEFLD 89
+A+KKI +++ +REI LL+ L+ +N+V + DI+ D +Y+VFE +D
Sbjct: 66 IAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMD 125
Query: 90 LDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKL 149
DL + + S +Q L + + F+ Q+ +G+ Y H+ ++HRDLKP NLL+N + +LK+
Sbjct: 126 TDLHQIIRS---NQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKI 182
Query: 150 GDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLF 209
DFGLAR T +VT WYRAPE+LL +Y++ +DVWS+GCIFAE+ R+PLF
Sbjct: 183 TDFGLARTTS-ETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLF 241
Query: 210 SGDSEIDQIFKIFRVLGTPNERTWPDI--IYLPDFKTTFPKWNRRNLSEVIPSLDANGID 267
G + Q+ I ++G+P+ + + + PK+ R+N S PS+++ ID
Sbjct: 242 PGKDYVHQLKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPSMNSTAID 301
Query: 268 LLDKLITYDPIHRISAKRAVQHPY 291
LL+K++ +DP+ RI+ + A+ +PY
Sbjct: 302 LLEKMLVFDPVKRITVEEALCYPY 325
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 187 bits (475), Expect = 2e-47
Identities = 112/292 (38%), Positives = 175/292 (59%), Gaps = 11/292 (3%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLES-EDEGVPSTAIREISLLKELKD 64
++++L+K+G+GTY VY+A DL Q ++VA+KK+R ++ E E V A REI +L+ L
Sbjct: 133 SFEKLDKIGQGTYSNVYRARDL-DQKKIVALKKVRFDNLEPESVRFMA-REIQILRRLDH 190
Query: 65 DNIVRLYDIVHSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
NI++L +V S LYLVFE+++ DL + S P + + +K ++ QL G+ +
Sbjct: 191 PNIIKLEGLVTSRMSCSLYLVFEYMEHDLAG-LASHPAIK-FSESQVKCYLQQLLHGLDH 248
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGV-PLRAYTHEIVTLWYRAPEVLLG 182
CH+ ++HRD+K NLLI+ G LK+ DFGLA F + T +VTLWYR PE+LLG
Sbjct: 249 CHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQTQPLTSRVVTLWYRPPELLLG 308
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW--PDIIYLP 240
+Y VD+WS GCI AE+ KP+ G +E++Q+ KIF++ G+P E W + +
Sbjct: 309 ATRYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDYWVKSRLPHAT 368
Query: 241 DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
FK T P +R + E + LL+ L++ +P R +A A++ +F
Sbjct: 369 IFKPTQP--YKRLVGETFKEFPQPALALLETLLSVNPDDRGTATAALKSEFF 418
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 187 bits (474), Expect = 2e-47
Identities = 107/296 (36%), Positives = 166/296 (55%), Gaps = 10/296 (3%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++++++K+G GTY VYKA D N +VA+KK+R + + REI +L+ L
Sbjct: 137 SFEKIDKIGSGTYSNVYKAKDSLTGN-IVALKKVRCDVNERESLKFMAREILILRRLDHP 195
Query: 66 NIVRLYDIVHSD-AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
N+++L +V S + LYLVF ++D DL S + +K +M QL G+ +C
Sbjct: 196 NVIKLEGLVTSRMSSSLYLVFRYMDHDLAGLAAS--PEIKFTEQQVKCYMKQLLSGLEHC 253
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-YTHEIVTLWYRAPEVLLGG 183
H ++HRD+K NLLI+ G L++GDFGLA F R T+ +VTLWYR+PE+L G
Sbjct: 254 HNRGVLHRDIKGSNLLIDDGGVLRIGDFGLATFFDASKRQEMTNRVVTLWYRSPELLHGV 313
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
+YS GVD+WS GCI AE+ + + G +E++Q+ +I+++ G+P+E W I K
Sbjct: 314 VEYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIRLPSTHK 373
Query: 244 ----TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
P++ RR + EV + LLD L+ DP R +A + +F E
Sbjct: 374 HAHHKPLPQYKRR-IREVYKDFSPEALSLLDTLLALDPAERQTATDVLMSDFFTTE 428
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 186 bits (473), Expect = 3e-47
Identities = 105/297 (35%), Positives = 168/297 (56%), Gaps = 15/297 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y L +GEG YG+V A+D ++RV A+KKI E + +REI +L K +N
Sbjct: 96 YVNLSYIGEGAYGMVASALDTITRDRV-AIKKIS-PFEHQTFCQRTLREIKILNRFKHEN 153
Query: 67 IVRLYDIVHSDA----HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
I+ + +I+ S+ +Y+V ++ DL + + K Q L + + F+ Q+ +G+
Sbjct: 154 IINIQEIIRSETVDSLKDIYIVQCLMETDLYKLL----KTQKLSNDHVCYFLYQILRGLK 209
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA---YTHEIVTLWYRAPEV 179
Y H+ ++HRDLKP NLL+N +LK+ DFGLAR T + T WYRAPE+
Sbjct: 210 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAPEI 269
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII-- 237
+L K Y+ +DVWS+GCI AEM + +PLF G +DQ+ I V+G+P+ II
Sbjct: 270 MLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIIND 329
Query: 238 YLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ + P ++ + + P D +DLLDK++T++P +RI ++A+ HPY ++
Sbjct: 330 KARSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLEQ 386
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 186 bits (473), Expect = 3e-47
Identities = 105/297 (35%), Positives = 168/297 (56%), Gaps = 15/297 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y L +GEG YG+V A+D ++RV A+KKI E + +REI +L K +N
Sbjct: 28 YVNLSYIGEGAYGMVASALDTITRDRV-AIKKIS-PFEHQTFCQRTLREIKILNRFKHEN 85
Query: 67 IVRLYDIVHSDA----HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
I+ + +I+ S+ +Y+V ++ DL + + K Q L + + F+ Q+ +G+
Sbjct: 86 IINIQEIIRSETVDSLKDIYIVQCLMETDLYKLL----KTQKLSNDHVCYFLYQILRGLK 141
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA---YTHEIVTLWYRAPEV 179
Y H+ ++HRDLKP NLL+N +LK+ DFGLAR T + T WYRAPE+
Sbjct: 142 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAPEI 201
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII-- 237
+L K Y+ +DVWS+GCI AEM + +PLF G +DQ+ I V+G+P+ II
Sbjct: 202 MLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIIND 261
Query: 238 YLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ + P ++ + + P D +DLLDK++T++P +RI ++A+ HPY ++
Sbjct: 262 KARSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLEQ 318
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 186 bits (472), Expect = 3e-47
Identities = 109/301 (36%), Positives = 183/301 (60%), Gaps = 20/301 (6%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRV--------VAMKKIRLE--SEDEGVPSTAI 53
+ Y L++VG+GT+G V++AV+ + N V VA+K+++ + S +E V +
Sbjct: 1 MERYTLLKEVGDGTFGNVWRAVN-KQTNEVGTEVFYVQVAIKRMKKKYFSWEECVN---L 56
Query: 54 REISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKF 113
RE+ L + NIV+L +++ + LY VFE+++ +L + M+ PK + I+ +
Sbjct: 57 REVKSLSRMNHPNIVKLKEVIREN-DILYFVFEYMECNLYQLMKDRPKH--FAESDIRNW 113
Query: 114 MMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLW 173
Q+ +G++Y H HRDLKP+NLL+++D +K+ D GLAR YT + T W
Sbjct: 114 CFQVFQGLSYMHQRGYFHRDLKPENLLVSKDV-IKIADLGLAREIDSS-PPYTEYVSTRW 171
Query: 174 YRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
YRAPEVLL Y++ VD+W++G I AE+ + +PLF G SE D+I+KI V+G+P E TW
Sbjct: 172 YRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETW 231
Query: 234 PDIIYLPD-FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
+ + L FP++ +LS V+P A+ ++L+++L ++DP +R + A+QHP+F
Sbjct: 232 LEGLNLASVINYQFPQFPGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEALQHPFF 291
Query: 293 K 293
+
Sbjct: 292 Q 292
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 186 bits (472), Expect = 3e-47
Identities = 116/331 (35%), Positives = 181/331 (54%), Gaps = 44/331 (13%)
Query: 1 MSELTNYKRLEKVGEGTYGVVYKAV-DLRHQNRVVAMKKIRLESEDEGVPSTAIREISLL 59
+ +L NY+ KVG GTYG VYKA + A+K+I + G+ +A REI+LL
Sbjct: 93 VEDLFNYEGC-KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALL 147
Query: 60 KELKDDNIVRLYDIV--HSDAHKLYLVFEFLDLDL------KRYMESIPKDQPLGGNIIK 111
+ELK N++ L + H+D K++L+ ++ + DL R ++ K + ++K
Sbjct: 148 RELKHQNVITLIRVFLSHND-RKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVK 206
Query: 112 KFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGN----LKLGDFGLARAFGVPLRAYTH 167
+ Q+ GI Y H++ ++HRDLKP N+L+ DGN +K+ D G AR F PL+
Sbjct: 207 SLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLAD 266
Query: 168 ---EIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLF---------SGDSEI 215
+VT WYRAPE+LLG + Y+ +D+W+IGCIFAE+ +P+F S
Sbjct: 267 LDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHH 326
Query: 216 DQIFKIFRVLGTPNERTWPDIIYLPDFKTTFPKWNRRNLS-----------EVIPSLDAN 264
DQ+ +IF V+G P ++ W DI +P+ T + R S ++ P D+
Sbjct: 327 DQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKP--DSK 384
Query: 265 GIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
LL KL+ DP RI++++A+Q YF+EE
Sbjct: 385 AFHLLQKLLLMDPNKRITSEQAMQDQYFQEE 415
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 186 bits (471), Expect = 4e-47
Identities = 105/297 (35%), Positives = 165/297 (55%), Gaps = 19/297 (6%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y RL K+GEG+YGVVYK + R ++VA+KK +D + A+REI +LK+LK
Sbjct: 1 MDKYDRLSKLGEGSYGVVYKCKN-RDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLK 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
N+V L ++ + KL+LVFE D + +E P + +IKK + QL + + +
Sbjct: 60 HQNLVGLIEVFKRN-RKLHLVFELCDRTVLHELEKNPHG--VNDELIKKIIYQLLEALKF 116
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
CH+H+ IHRD+KP+N+ + R+ +KLGDFG AR YT + T WYR+PE+L+G
Sbjct: 117 CHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTT-EMYTDYVATRWYRSPELLVGD 175
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
QY VD+W++GC++AE+ + L+ G S+IDQ++ I + LG R ++ F+
Sbjct: 176 VQYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLGEFLPR------HISIFR 229
Query: 244 T-------TFPK-WNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
T + P+ + L +P+ + +D L K P R S + H F
Sbjct: 230 TNQFFFGLSIPEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIF 286
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 185 bits (470), Expect = 6e-47
Identities = 109/284 (38%), Positives = 168/284 (58%), Gaps = 7/284 (2%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
+++LEK+G+GTY V++A ++ ++VA+KK++ ++ REI +L++L N
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVE-TGKMVALKKVKFDNLQPESIRFMAREILILRKLNHPN 163
Query: 67 IVRLYDIVHSDAHK-LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
I++L IV S A +YLVFE+++ DL + S P D IK +M QL G+ +CH
Sbjct: 164 IMKLEGIVTSRASSSIYLVFEYMEHDLAG-LSSNP-DIRFTEPQIKCYMKQLLWGLEHCH 221
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLR-AYTHEIVTLWYRAPEVLLGGK 184
+IHRD+K N+L+N G LKLGDFGLA + T +VTLWYRAPE+L+G
Sbjct: 222 MRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSRVVTLWYRAPELLMGST 281
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKT 244
Y VD+WS+GC+FAE+ KP+ G +EI+Q+ KI+++ G+P + W LP +
Sbjct: 282 SYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSPQDSFWKR-TKLPHATS 340
Query: 245 TFPKWN-RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
P+ L E L A G+ LL+ L++ +P R +A A+
Sbjct: 341 FKPQHTYEATLRERCKDLSATGVYLLETLLSMEPDKRGTASSAL 384
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 184 bits (468), Expect = 1e-46
Identities = 107/293 (36%), Positives = 170/293 (57%), Gaps = 11/293 (3%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLE--SEDEGVPSTAIREISLLKE 61
+ Y + ++G+GTYG V + ++A+KK++ + S +E + RE+ LK+
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIE-SGELIAIKKMKRKFYSWEECMNQ---REVKSLKK 56
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L N+V+L +++ + H LY +FE++ +L + ++ K P + I+ M Q+ +G+
Sbjct: 57 LNHANVVKLKEVIRENDH-LYFIFEYMKENLYQLIKERNKLFP--ESAIRNIMYQILQGL 113
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
A+ H HRDLKP+NLL +K+ DFGLAR YT + T WYRAPEVLL
Sbjct: 114 AFIHKLGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLL 172
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD 241
YS+ +DVW++GCI AE+ +PLF G SEID IFKI +VLGTP + WP+ L
Sbjct: 173 RSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSS 232
Query: 242 -FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+P+ NL +IP+ + + LL ++ +DP R +A +A+++PYF+
Sbjct: 233 AMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 184 bits (467), Expect = 1e-46
Identities = 110/335 (32%), Positives = 181/335 (53%), Gaps = 45/335 (13%)
Query: 1 MSELTNYKRLEKVGEGTYGVVYKAVDLRHQ----NRVVAMKKIRLESEDEGVPSTAIREI 56
+ +L ++ +++G GTYG+VYKAV + N+ A+K I E +G +A REI
Sbjct: 20 VEDLFYFENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMI----EGQGFSMSACREI 75
Query: 57 SLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDL----KRYMESIPKDQPL--GGNII 110
+L +EL+ N++ L + ++ K++L+ ++ + DL K + + K P+ N++
Sbjct: 76 ALFRELRHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMV 135
Query: 111 KKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDG------NLKLGDFGLARAFGVPLRA 164
K + Q+ G+ Y H++ ++HRDLKP N+L+ DG +K+ D G +R + PL+
Sbjct: 136 KNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKP 195
Query: 165 YTH---EIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSE------- 214
+VT WYRAPE+LLG K Y+ +DVW+IGCIFAE+ +PLF E
Sbjct: 196 MAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNP 255
Query: 215 --IDQIFKIFRVLGTPNERTWPDIIYLPDFK-------------TTFPKWNRRNLSEVIP 259
DQ+ +IF +LG P++ WPD+ +PD + TFP R +
Sbjct: 256 YHYDQVKRIFHLLGYPSDADWPDMKKMPDHQRLLSDARNEGTPIQTFPNSLHRYFDKWKI 315
Query: 260 SLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ ++ LL KL+T DP R+S + A+ YF++
Sbjct: 316 NSQSSPYRLLVKLLTVDPTKRVSCEEAMNDIYFRK 350
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 184 bits (466), Expect = 2e-46
Identities = 104/287 (36%), Positives = 172/287 (59%), Gaps = 29/287 (10%)
Query: 35 AMKKIRLESED------EGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFL 88
A+KK + E + G+ +A RE++L +EL + ++ L +I + +++V+E+
Sbjct: 181 AIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIF-LERKCVHMVYEYA 239
Query: 89 DLDLKR--YMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGN 146
+ DL + + S P+ + + +++ M QL G++Y H + ++HRDLKP N+++ DG
Sbjct: 240 EHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGC 299
Query: 147 LKLGDFGLARAFGVPLRA-YTHE--IVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMC 203
+K+GD GLAR F L+ YT + +VT+WYRAPE+LLG + Y+ VD+WS+GCIFAE+
Sbjct: 300 VKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELI 359
Query: 204 NRKPLFSGDS-----------EIDQIFKIFRVLGTPNERTWPDIIYLPDFK--TTFPKWN 250
+P+F G+ +++Q+ +I VLGTP+++ WP + P++ T FPK+
Sbjct: 360 GLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKY- 418
Query: 251 RRNLSEVIPSL---DANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
R NL+ S D + + LL L+ YDPI RI A A++H YF E
Sbjct: 419 RDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTE 465
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 184 bits (466), Expect = 2e-46
Identities = 112/290 (38%), Positives = 160/290 (54%), Gaps = 12/290 (4%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVD-LRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
T Y L+ +G G +G+V A D L N VA+KKI + RE+ LLK L+
Sbjct: 18 TRYSDLQPIGMGAFGLVCSAKDQLTGMN--VAVKKIMKPFSTPVLAKRTYRELKLLKHLR 75
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
+NI+ L DI S +Y V E L DL R + S +PL I+ F+ Q+ +G+ +
Sbjct: 76 HENIISLSDIFISPFEDIYFVTELLGTDLHRLLTS----RPLETQFIQYFLYQILRGLKF 131
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
H+ +IHRDLKP N+LIN + +LK+ DFGLAR + Y + T +YRAPE++L
Sbjct: 132 VHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTW 188
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD-- 241
++Y+ VD+WS GCIFAEM KPLF G ++Q I +LGTP I
Sbjct: 189 QKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICSKNTLR 248
Query: 242 FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
F + P+ + +E + D + IDLL+K++ +DP RISA A+ H Y
Sbjct: 249 FVQSLPQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAADALAHNY 298
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 182 bits (463), Expect = 4e-46
Identities = 109/292 (37%), Positives = 163/292 (55%), Gaps = 11/292 (3%)
Query: 3 ELTN-YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
E+TN Y L VG G +G+V A D ++ VA+KKI + RE+ LLK
Sbjct: 18 EITNRYNDLNPVGMGAFGLVCSATDTL-TSQPVAIKKIMKPFSTAVLAKRTYRELKLLKH 76
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L+ +N++ L DI S +Y V E DL R +++ +PL ++ F+ Q+ +G+
Sbjct: 77 LRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQT----RPLEKQFVQYFLYQILRGL 132
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y H+ +IHRDLKP N+LIN + +LK+ DFGLAR + Y + T +YRAPE++L
Sbjct: 133 KYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIML 189
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII--YL 239
++Y VD+WS GCIFAEM KPLF G + Q I +LG+P + I
Sbjct: 190 TWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENT 249
Query: 240 PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
F T+ P + SE +++ + +DLL+K++ +DP RI+A A+ HPY
Sbjct: 250 LKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPY 301
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 182 bits (463), Expect = 4e-46
Identities = 112/295 (37%), Positives = 171/295 (57%), Gaps = 16/295 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLES-EDEGVPSTAIREISLLKELKDD 65
+++LEK+G+GTY V++A + R+VA+KK+R ++ E E V A REI +L++L
Sbjct: 131 FEKLEKIGQGTYSSVFRARETE-TGRIVALKKVRFDNFEPESVRFMA-REILILRKLNHP 188
Query: 66 NIVRLYDIVHSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
NI++L IV S ++LVFE+++ DL + S D IK +M QL G+ +C
Sbjct: 189 NIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSS--PDIDFTTPQIKCYMKQLLSGLDHC 246
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP--LRAYTHEIVTLWYRAPEVLLG 182
HA ++HRD+K NLL+N +G LK+ DFGLA + T +VTLWYR PE+LLG
Sbjct: 247 HARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTSRVVTLWYRPPELLLG 306
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDF 242
+Y VD+WS+GC+FAE+ KP+ G +E++Q+ KIF++ G+P E W LP
Sbjct: 307 ATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPEDYWKK-SKLPHA 365
Query: 243 KTTFPKWN-----RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
P+ + R L + L I+L++ L++ P R +A A+ YF
Sbjct: 366 MLFKPQQHYDGCLRETLK--LKGLSDADINLIETLLSIQPHKRGTASTALVSQYF 418
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 179 bits (454), Expect = 4e-45
Identities = 107/299 (35%), Positives = 166/299 (54%), Gaps = 25/299 (8%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPST-AIREISLLKELKDDNIVRLY 71
+GEG YGVV A + +VA+KKI E D+ + + +REI +LK K +NI+ ++
Sbjct: 19 LGEGAYGVVCSATH-KPTGEIVAIKKI--EPFDKPLFALRTLREIKILKHFKHENIITIF 75
Query: 72 DIVHSDA----HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAH 127
+I D+ +++Y++ E + DL R + + Q L + I+ F+ Q + + H
Sbjct: 76 NIQRPDSFENFNEVYIIQELMQTDLHRVIST----QMLSDDHIQYFIYQTLRAVKVLHGS 131
Query: 128 RIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPL----------RAYTHEIVTLWYRAP 177
+IHRDLKP NLLIN + +LK+ DFGLAR T + T WYRAP
Sbjct: 132 NVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAP 191
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
EV+L +YS +DVWS GCI AE+ R+P+F G Q+ IF ++GTP+ I
Sbjct: 192 EVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCI 251
Query: 238 YLP---DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
P ++ + P + L ++ P ++ GIDLL +++ +DP RI+AK A++HPY +
Sbjct: 252 ESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQ 310
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 179 bits (454), Expect = 4e-45
Identities = 97/291 (33%), Positives = 163/291 (55%), Gaps = 17/291 (5%)
Query: 10 LEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 69
+E +G G YG+V A + N VA+KKI ++ +REI LL + DN+++
Sbjct: 36 IEPIGRGAYGIVCCATN-SETNEEVAIKKIANAFDNRVDAKRTLREIKLLSHMDHDNVIK 94
Query: 70 LYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
+ DI+ + +Y+V+E +D DL + + S Q L + + F+ Q+ +G+ Y H
Sbjct: 95 IKDIIELPEKERFEDVYIVYELMDTDLHQIIRST---QTLTDDHCQYFLYQILRGLKYIH 151
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ ++HRDLKP NL++N + +LK+ DFGLAR T +VT WYRAPE+LL +
Sbjct: 152 SANVLHRDLKPSNLVLNTNCDLKICDFGLARTSN-ETEIMTEYVVTRWYRAPELLLNSSE 210
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD---- 241
Y+ +D+WS+GCIF E+ R+ LF G + Q+ I +LG+P++ D+ +L
Sbjct: 211 YTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDD---SDLDFLRSDNAR 267
Query: 242 -FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ P +++ E P++ +DL +K++ +DP RI+ A++ PY
Sbjct: 268 KYVKQLPHVQKQSFREKFPNISPMALDLAEKMLVFDPSKRITVDEALKQPY 318
>CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 489
Score = 178 bits (452), Expect = 7e-45
Identities = 102/263 (38%), Positives = 150/263 (56%), Gaps = 27/263 (10%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQN----------RVVAMKKIRLESEDEGVPSTA 52
+++ Y++L K+G+GT+G V + R+ R+VA+KKI +E+E EG P TA
Sbjct: 81 DVSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITA 140
Query: 53 IREISLLKELKDDNIVRLYDIVHS---------DAHKLYLVFEFLDLDLKRYMESIPKDQ 103
+RE+ +L++LK NI L ++ + D YLV DL + + PK +
Sbjct: 141 LREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSN-PKIR 199
Query: 104 PLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF----- 158
+ IK M L G+ H +I+HRD+K N+LI++DG LKL DFGLAR F
Sbjct: 200 -MSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQREN 258
Query: 159 -GVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQ 217
P YT+ +VTLWYR PE+LLG +QY T +DVW GCI AEM R+P+ GD+E Q
Sbjct: 259 GAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQ 318
Query: 218 IFKIFRVLGTPNERTWPDIIYLP 240
+ I + G+ N+ WP+ + +P
Sbjct: 319 LQLISGLCGSINKDVWPNCVNMP 341
>CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 456
Score = 178 bits (452), Expect = 7e-45
Identities = 102/263 (38%), Positives = 150/263 (56%), Gaps = 27/263 (10%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQN----------RVVAMKKIRLESEDEGVPSTA 52
+++ Y++L K+G+GT+G V + R+ R+VA+KKI +E+E EG P TA
Sbjct: 81 DVSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITA 140
Query: 53 IREISLLKELKDDNIVRLYDIVHS---------DAHKLYLVFEFLDLDLKRYMESIPKDQ 103
+RE+ +L++LK NI L ++ + D YLV DL + + PK +
Sbjct: 141 LREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSN-PKIR 199
Query: 104 PLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF----- 158
+ IK M L G+ H +I+HRD+K N+LI++DG LKL DFGLAR F
Sbjct: 200 -MSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQREN 258
Query: 159 -GVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQ 217
P YT+ +VTLWYR PE+LLG +QY T +DVW GCI AEM R+P+ GD+E Q
Sbjct: 259 GAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQ 318
Query: 218 IFKIFRVLGTPNERTWPDIIYLP 240
+ I + G+ N+ WP+ + +P
Sbjct: 319 LQLISGLCGSINKDVWPNCVNMP 341
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 177 bits (449), Expect = 2e-44
Identities = 104/300 (34%), Positives = 164/300 (54%), Gaps = 23/300 (7%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ +E +G G YGVV A R + VA+KKI + +RE+ +LK K DN
Sbjct: 55 YEIIETIGNGAYGVVSSA-RRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 67 IVRLYDIV-----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
I+ + DI+ + + +Y+V + ++ DL + + S QPL ++ F+ QL +G+
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLRGL 170
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAY----THEIVTLWYRAP 177
Y H+ ++IHRDLKP NLL+N + LK+GDFG+AR + T + T WYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
E++L +Y+ +D+WS+GCIF EM R+ LF G + + Q+ I VLGTP+ P +I
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPS----PAVI 286
Query: 238 Y------LPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ + + P V P D + LL +++ ++P RISA A++HP+
Sbjct: 287 QAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPF 346
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 177 bits (449), Expect = 2e-44
Identities = 104/300 (34%), Positives = 164/300 (54%), Gaps = 23/300 (7%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ +E +G G YGVV A R + VA+KKI + +RE+ +LK K DN
Sbjct: 55 YEIIETIGNGAYGVVSSA-RRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113
Query: 67 IVRLYDIV-----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
I+ + DI+ + + +Y+V + ++ DL + + S QPL ++ F+ QL +G+
Sbjct: 114 IIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS---SQPLTLEHVRYFLYQLLRGL 170
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAY----THEIVTLWYRAP 177
Y H+ ++IHRDLKP NLL+N + LK+GDFG+AR + T + T WYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
E++L +Y+ +D+WS+GCIF EM R+ LF G + + Q+ I VLGTP+ P +I
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPS----PAVI 286
Query: 238 Y------LPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ + + P V P D + LL +++ ++P RISA A++HP+
Sbjct: 287 QAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPF 346
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 177 bits (448), Expect = 2e-44
Identities = 109/295 (36%), Positives = 163/295 (54%), Gaps = 10/295 (3%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMK-KIRLESEDEGVPSTAIREISLLKEL 62
+ NYK + K+GEGT+ V K LR N + K R ES ++ +REI L+ L
Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ---VNNLREIQALRRL 57
Query: 63 KDD-NIVRLYDIVHS-DAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
NI+ L+++V + L L+ E +D+++ + + PL I +M QLCK
Sbjct: 58 NPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRG--RRYPLSEKKIMHYMYQLCKS 115
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
+ + H + I HRD+KP+N+LI +D LKLGDFG R+ + YT I T WYRAPE L
Sbjct: 116 LDHIHRNGIFHRDVKPENILIKQDV-LKLGDFGSCRSV-YSKQPYTEYISTRWYRAPECL 173
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
L Y+ +D+WS GC+F E+ + +PLF G +E+DQI KI V+GTP ++
Sbjct: 174 LTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSR 233
Query: 241 DFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
FP + + +L + LL ++ YDP RI+A +A+QHPYF+E+
Sbjct: 234 AMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQ 288
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 176 bits (446), Expect = 4e-44
Identities = 101/298 (33%), Positives = 160/298 (52%), Gaps = 18/298 (6%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ L+ VG+G YG V KAV +R + VA+KK+ + RE+ LLK + +N
Sbjct: 24 YQNLQPVGQGAYGQVCKAV-VRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHEN 82
Query: 67 IVRLYDIVH--------SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
++ L D+ H ++Y+V +D DL +I + Q L + ++ + Q+
Sbjct: 83 VIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLN----NIIRTQKLSDDHVQFLVYQIL 138
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+G+ Y H+ +IHRDLKP N+ +N D L++ DFGLAR + Y + T WYRAPE
Sbjct: 139 RGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGY---VATRWYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII- 237
++L Y+ D+WS+GCI AE+ + LF G I Q+ I VLGTP + I
Sbjct: 196 IMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISS 255
Query: 238 -YLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
++ + P RRN ++ + IDLL+K++ D RI+A++A+ HPY ++
Sbjct: 256 ESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEK 313
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 175 bits (444), Expect = 6e-44
Identities = 105/294 (35%), Positives = 164/294 (55%), Gaps = 15/294 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ + +G+G YGVV A+ + VA+KKI + T +REI LL+ + +N
Sbjct: 39 YEMINLIGQGAYGVVCAALH-KPSGLKVAVKKIHPFNHPVFCLRT-LREIKLLRHFRHEN 96
Query: 67 IVRLYDIV----HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
I+ + DI+ + + +Y+V E ++ DL R + S QPL + + F Q+ + +
Sbjct: 97 IISILDILPPPSYQELEDVYIVQELMETDLYRVIRS----QPLSDDHCQYFTYQILRALK 152
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR---AFGVPLRAYTHEIVTLWYRAPEV 179
H+ ++HRDLKP NLL+N + +LK+ DFGLAR A G T + T WYRAPE+
Sbjct: 153 AMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPEI 212
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI--I 237
+L ++YS +D+WS GCI AEM + +PLF G QI I +LGTP + I
Sbjct: 213 MLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKSA 272
Query: 238 YLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ + P + + + P + IDLL+KL+T++P RI+A+ A++HPY
Sbjct: 273 RARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALKHPY 326
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 175 bits (444), Expect = 6e-44
Identities = 100/288 (34%), Positives = 156/288 (53%), Gaps = 16/288 (5%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
VG G YG V A+D R +V A+KK+ + E A RE+ LLK ++ +N++ L D
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKV-AIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLD 89
Query: 73 IVHSDA-----HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAH 127
+ + + YLV F+ DL++ M ++ I+ + Q+ KG+ Y H+
Sbjct: 90 VFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEEK-----IQYLVYQMLKGLKYIHSA 144
Query: 128 RIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYS 187
++HRDLKP NL +N D LK+ DFGLAR + Y +VT WYRAPEV+L Y+
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGY---VVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI--IYLPDFKTT 245
VD+WS+GCI AEM K LF G +DQ+ +I +V G P + + +
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 246 FPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
P+ R++ +++ P DLL+K++ D R++A +A+ HP+F+
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFE 309
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 175 bits (443), Expect = 8e-44
Identities = 108/295 (36%), Positives = 166/295 (55%), Gaps = 20/295 (6%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+G G +GVV+ D R RV A+KK+ ++ REI +L + DN++ L D
Sbjct: 49 IGYGAFGVVWSVTDPRSGKRV-ALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLD 107
Query: 73 IVH----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHR 128
I+ S +LY++ E + DL + + S Q L + +K F+ Q+ +G+ Y H
Sbjct: 108 ILQPANPSFFQELYVLTELMQSDLHKIIVS---PQALTPDHVKVFVYQILRGLKYLHTAN 164
Query: 129 IIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-YTHEIVTLWYRAPEVLLGGKQYS 187
I+HRD+KP NLL+N + LK+ DFGLAR + R THE+VT +YRAPE+L+G ++Y+
Sbjct: 165 ILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYT 224
Query: 188 TGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD------ 241
VD+WS+GCIFAE+ RK LF I+Q+ I +LGTP++ + Y +
Sbjct: 225 GAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEA---MKYACEGAKNHV 281
Query: 242 FKTTFPKWNRRNLSEVIPSLDAN--GIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ + + L ++ D N +DLL KL+ +DP RIS + A+QH Y +E
Sbjct: 282 LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 336
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 175 bits (443), Expect = 8e-44
Identities = 108/295 (36%), Positives = 166/295 (55%), Gaps = 20/295 (6%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+G G +GVV+ D R RV A+KK+ ++ REI +L + DN++ L D
Sbjct: 74 IGYGAFGVVWSVTDPRSGKRV-ALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLD 132
Query: 73 IVH----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHR 128
I+ S +LY++ E + DL + + S Q L + +K F+ Q+ +G+ Y H
Sbjct: 133 ILQPANPSFFQELYVLTELMQSDLHKIIVS---PQALTPDHVKVFVYQILRGLKYLHTAN 189
Query: 129 IIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-YTHEIVTLWYRAPEVLLGGKQYS 187
I+HRD+KP NLL+N + LK+ DFGLAR + R THE+VT +YRAPE+L+G ++Y+
Sbjct: 190 ILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYT 249
Query: 188 TGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD------ 241
VD+WS+GCIFAE+ RK LF I+Q+ I +LGTP++ + Y +
Sbjct: 250 GAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEA---MKYACEGAKNHV 306
Query: 242 FKTTFPKWNRRNLSEVIPSLDAN--GIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ + + L ++ D N +DLL KL+ +DP RIS + A+QH Y +E
Sbjct: 307 LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 361
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 175 bits (443), Expect = 8e-44
Identities = 108/295 (36%), Positives = 166/295 (55%), Gaps = 20/295 (6%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+G G +GVV+ D R RV A+KK+ ++ REI +L + DN++ L D
Sbjct: 246 IGYGAFGVVWSVTDPRSGKRV-ALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLD 304
Query: 73 IVH----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHR 128
I+ S +LY++ E + DL + + S Q L + +K F+ Q+ +G+ Y H
Sbjct: 305 ILQPANPSFFQELYVLTELMQSDLHKIIVS---PQALTPDHVKVFVYQILRGLKYLHTAN 361
Query: 129 IIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-YTHEIVTLWYRAPEVLLGGKQYS 187
I+HRD+KP NLL+N + LK+ DFGLAR + R THE+VT +YRAPE+L+G ++Y+
Sbjct: 362 ILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYT 421
Query: 188 TGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD------ 241
VD+WS+GCIFAE+ RK LF I+Q+ I +LGTP++ + Y +
Sbjct: 422 GAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEA---MKYACEGAKNHV 478
Query: 242 FKTTFPKWNRRNLSEVIPSLDAN--GIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ + + L ++ D N +DLL KL+ +DP RIS + A+QH Y +E
Sbjct: 479 LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 533
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 175 bits (443), Expect = 8e-44
Identities = 112/302 (37%), Positives = 165/302 (54%), Gaps = 33/302 (10%)
Query: 11 EKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK-DDNIVR 69
+++G+G YG+V+KA D R +N VA+KK+ DE RE+ L+ + NIVR
Sbjct: 29 KRMGKGAYGIVWKATDRRTKN-TVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVR 87
Query: 70 LYDIVHSDAH-KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIK----KFMM-QLCKGIAY 123
L DI + + YLVFEF++ DL ++ GN++K +F+M QL I +
Sbjct: 88 LVDIFKASNNLDFYLVFEFMESDLHNVIKR--------GNVLKDVHKRFVMYQLINAIKF 139
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAY---------THEIVTLWY 174
H+ +IHRDLKP N+LI+ LK+ DFGLAR R Y T + T WY
Sbjct: 140 IHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLS-SRRIYDDLEQDGMLTDYVATRWY 198
Query: 175 RAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWP 234
RAPE+L+ + Y+ G+D+W +GCI EM +KPLF G S ++QI KI V PN
Sbjct: 199 RAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI--VTSLPNVTKLD 256
Query: 235 DIIYLPDFKTTFPKWN-----RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQH 289
P F + N R +L E++ + +GI L+ L+ +P +R++AK A++H
Sbjct: 257 IASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRH 316
Query: 290 PY 291
PY
Sbjct: 317 PY 318
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 174 bits (442), Expect = 1e-43
Identities = 104/296 (35%), Positives = 166/296 (55%), Gaps = 22/296 (7%)
Query: 11 EKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL-KDDNIVR 69
+++G+G YG+V+KA D R + VA+KKI + RE+ L+E K N+++
Sbjct: 17 KRLGKGAYGIVWKAYDKRSRE-TVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIK 75
Query: 70 LYDIVHSDAHK-LYLVFEFLDLDLKRYME--SIPKDQPLGGNIIKKFMM-QLCKGIAYCH 125
LY+I +D + +YL FEF++ DL ++ SI KD + K+++M QL + I + H
Sbjct: 76 LYNIFRADNDRDIYLAFEFMEADLHNVIKKGSILKD------VHKQYIMCQLFRAIRFLH 129
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF--------GVPLRAYTHEIVTLWYRAP 177
+ ++HRDLKP N+L++ D +KL DFGLAR+ G + T + T WYR+P
Sbjct: 130 SGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSP 189
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI- 236
E+LL K+Y+ GVD+WS+GCI AEM + LF G S I+QI +I + P+ I
Sbjct: 190 EILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIG 249
Query: 237 -IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
Y P+ R+ L +I ID++ +L+ + P R++ ++ + HPY
Sbjct: 250 SHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHPY 305
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 174 bits (442), Expect = 1e-43
Identities = 104/298 (34%), Positives = 157/298 (51%), Gaps = 18/298 (6%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ L+ VG G YG V KAV +R N VA+KK+ + RE+ LLK + +N
Sbjct: 25 YQDLQPVGSGAYGQVSKAV-VRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHEN 83
Query: 67 IVRLYDIVH--------SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
++ L DI H + ++YLV +D DL +I + Q L + ++ + Q+
Sbjct: 84 VIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLN----NIIRMQHLSDDHVQFLVYQIL 139
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+G+ Y H+ +IHRDLKP N+ +N D L++ DFGLAR + Y + T WYRAPE
Sbjct: 140 RGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGY---VATRWYRAPE 196
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII- 237
++L Y VD+WS+GCI AE+ R+ LF G I Q+ I +LGTP I
Sbjct: 197 IMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISS 256
Query: 238 -YLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ + P R+ V + + IDLL+K++ D RI+A+ A+ HPY ++
Sbjct: 257 ESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEK 314
>Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 240
Score = 174 bits (441), Expect = 1e-43
Identities = 76/127 (59%), Positives = 97/127 (75%)
Query: 168 EIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGT 227
++VTLWYR+PEVLLG +YST VD+WSIG IFAE+ +KPLF GDSEIDQ+F+IFR LGT
Sbjct: 106 KVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT 165
Query: 228 PNERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
PN WP++ L D+K TFPKW +L+ + +LD NG+DLL K++ YDP RIS K A+
Sbjct: 166 PNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMAL 225
Query: 288 QHPYFKE 294
HPYF +
Sbjct: 226 NHPYFND 232
Score = 127 bits (320), Expect = 1e-29
Identities = 66/110 (60%), Positives = 88/110 (80%), Gaps = 6/110 (5%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQN--RVVAMKKIRLESEDEGVPSTAIREISLLKE 61
+ +Y ++EK+GEGTYGVVYK RH+ +VVAMKKIRLESE+EGVPSTAIREISLLKE
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKG---RHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKE 57
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIK 111
L+ NIV L D++ D+ +LYL+FEFL +DLK+Y++SIP Q + +++K
Sbjct: 58 LRHPNIVSLQDVLMQDS-RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVK 106
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 174 bits (441), Expect = 1e-43
Identities = 96/290 (33%), Positives = 171/290 (58%), Gaps = 11/290 (3%)
Query: 7 YKRLEKVGEGTYGVVY--KAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
Y +++G+GT+G V K +D + + MKK + S +E + ++RE+ LK+L
Sbjct: 45 YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKK-KFYSWEEAM---SLREVKSLKKLNH 100
Query: 65 DNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
NI++L +++ + LY VFEF+ +L M+ +D+ ++I+ + Q+ +G+A+
Sbjct: 101 PNIIKLREVIREN-DILYFVFEFMQENLYELMKD--RDRYFPESVIRNIIYQVLQGLAFM 157
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H + HRD+KP+N++ N +K+ DFGLAR YT + T WYRAPE+LL
Sbjct: 158 HKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEILLRST 216
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD-FK 243
Y++ +D+W++GCI AE+ +PLF G SE+DQ+FKI +LGTPN+ WP+ L
Sbjct: 217 SYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMN 276
Query: 244 TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
F + + +V+ ++ G+ L+ ++ ++P R +A +++++ YF+
Sbjct: 277 FRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYFQ 326
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 174 bits (440), Expect = 2e-43
Identities = 107/297 (36%), Positives = 160/297 (53%), Gaps = 14/297 (4%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNR-VVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
N+K ++++G+G YG+V A ++ +++ VA+KKI + A+REI LL ++
Sbjct: 20 NFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRN 79
Query: 65 D-NIVRLYD---IVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
NI +YD I + +++Y+ E ++ DL ++S QPL + F+ Q+ G
Sbjct: 80 HRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKS---GQPLTDAHFQSFIYQILCG 136
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA----YTHEIVTLWYRA 176
+ Y H+ +IHRDLKP NLL+N D LK+ DFGLAR T + T WYRA
Sbjct: 137 LKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYRA 196
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE++L Y G+DVWS+GCI AE+ PLF G + Q+ I LGTP+E T I
Sbjct: 197 PEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSHI 256
Query: 237 --IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
++ + PK P + +DLL KL+ +DP RIS A++HPY
Sbjct: 257 SSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDALEHPY 313
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 174 bits (440), Expect = 2e-43
Identities = 104/292 (35%), Positives = 154/292 (52%), Gaps = 15/292 (5%)
Query: 10 LEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 69
L VG G YG V A D R + +V A+KK+ + RE+ LLK LK +N++
Sbjct: 27 LRPVGSGAYGSVCSAYDARLRQKV-AVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 70 LYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
L D+ D ++YLV + DL +I K Q L ++ + QL +G+ Y
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLN----NIVKCQALSDEHVQFLVYQLLRGLKYI 141
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 184
H+ IIHRDLKP N+ +N D L++ DFGLAR + Y + T WYRAPE++L
Sbjct: 142 HSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGY---VATRWYRAPEIMLNWM 198
Query: 185 QYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII--YLPDF 242
Y+ VD+WS+GCI AE+ K LF G IDQ+ +I V+GTP+ I + +
Sbjct: 199 HYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY 258
Query: 243 KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ P +++LS + + IDLL +++ D R+SA A+ H YF +
Sbjct: 259 IQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQ 310
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 172 bits (435), Expect = 7e-43
Identities = 108/295 (36%), Positives = 162/295 (54%), Gaps = 22/295 (7%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+G G +GVV+ D R RV A+KK+ ++ RE+ +L K DN++ D
Sbjct: 132 IGYGAFGVVWSVTDPRDGKRV-ALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALD 190
Query: 73 IV---HSDA-HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHR 128
I+ H D ++Y+V E + DL + + S QPL + +K F+ Q+ +G+ Y H+
Sbjct: 191 ILQPPHIDYFEEIYVVTELMQSDLHKIIVS---PQPLSSDHVKVFLYQILRGLKYLHSAG 247
Query: 129 IIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP-LRAYTHEIVTLWYRAPEVLLGGKQYS 187
I+HRD+KP NLL+N + LK+ DFGLAR + R T E+VT +YRAPE+L+G + YS
Sbjct: 248 ILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYS 307
Query: 188 TGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPN--------ERTWPDIIYL 239
+D+WS+GCIFAE+ R+ LF S I Q+ I +LGTP+ E I+
Sbjct: 308 NAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRG 367
Query: 240 PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P + + P L + + LL +++ +DP RISAK A+ HPY E
Sbjct: 368 PHKQPSLPV-----LYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 417
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 172 bits (435), Expect = 7e-43
Identities = 101/307 (32%), Positives = 167/307 (53%), Gaps = 23/307 (7%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E T Y E +G G +GVV +A+D + N+ VA+KKI +++ A+REI + +EL
Sbjct: 40 EATQYLAQENLGAGAFGVVCRAIDSK-LNKQVAIKKITRVFKNQSTAKCALREIRITREL 98
Query: 63 KDDNIVRLYDIVHSDA---HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
+NI+ D++ ++ +Y+V + ++ DL ++S +Q L + F Q+ K
Sbjct: 99 SHENIINSTDVLMRESGSGQDIYIVMDLMETDLLSVLKS---NQTLNEKHFQYFFYQILK 155
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-------------YT 166
G+ Y H+ IIHRDLKP NLL+N D +LK+ DFG++R+ G + +
Sbjct: 156 GLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRS-GPSTKTTPNTSPNAHISGDLS 214
Query: 167 HEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLG 226
+ TLWYRAPE+LL +Y T VD+WS GCI AEM +P+F+G QI + LG
Sbjct: 215 QYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLG 274
Query: 227 TPNERTWPDI--IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAK 284
TP+E+ I + D+ ++F + + P+ +++ K++ P R SA+
Sbjct: 275 TPDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAE 334
Query: 285 RAVQHPY 291
+ ++ P+
Sbjct: 335 QLLEEPF 341
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 171 bits (432), Expect = 1e-42
Identities = 105/300 (35%), Positives = 170/300 (56%), Gaps = 31/300 (10%)
Query: 11 EKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRL 70
+ +G G G+V AVD R R VA+KKI L D A+REI +++ L DNIV++
Sbjct: 24 QPLGFGVNGLVLSAVDSR-ACRKVAVKKIALS--DARSMKHALREIKIIRRLDHDNIVKV 80
Query: 71 YDIVHSDAHKL----------YLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
Y+++ L Y+V E+++ DL R +E L K FM QL +G
Sbjct: 81 YEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQ----GTLAEEHAKLFMYQLLRG 136
Query: 121 IAYCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYTHE------IVTLW 173
+ Y H+ ++HRDLKP N+ I+ D LK+GDFGLAR + Y+H+ +VT W
Sbjct: 137 LKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVD---QHYSHKGYLSEGLVTKW 193
Query: 174 YRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
YR+P +LL Y+ +D+W+ GCI AEM + LF+G E++Q+ I + E
Sbjct: 194 YRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDK 253
Query: 234 PDII-YLPDFKTTFPKWN-RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+++ +P F ++ W +R L +++P +++ ID L+K++T++P+ R++A+ +QHPY
Sbjct: 254 DELLRVMPSFVSS--TWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPY 311
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 170 bits (431), Expect = 2e-42
Identities = 112/312 (35%), Positives = 160/312 (50%), Gaps = 30/312 (9%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E T Y E VG G YGVV KA+D R++ +V A+KKI + ++RE+ +L+EL
Sbjct: 53 EGTPYLAEENVGAGAYGVVCKAMDTRNKKQV-AIKKIPRAFTAHTLAKRSLREVRILREL 111
Query: 63 KDDNIVRLYDIVHSD-AH--KLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
+NI+ + D+ ++ AH +YLV + ++ DL + + S Q L + F QL +
Sbjct: 112 LHENIIAVLDMFTAEGAHGKDIYLVMDLMETDLHQILHS---RQTLMEQHFQYFFYQLLR 168
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA---------YTHEIV 170
G+ Y H+ IIHRDLKP NLL+N D L++ DFG+ARA+ T +
Sbjct: 169 GLKYLHSAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVS 228
Query: 171 TLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNE 230
T WYRAPE+L +Y T VD+WS GCIFAEM R+ LF G + QI I LG+P E
Sbjct: 229 TRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEE 288
Query: 231 RT--------WPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRIS 282
D I KT P S + P +++ L+ P R S
Sbjct: 289 EVINRITSDLVRDSIEACGRKTPLP------FSAIFPKASPEARNMVSYLLQISPWKRYS 342
Query: 283 AKRAVQHPYFKE 294
A + +QHP+ +
Sbjct: 343 ADQILQHPFMAQ 354
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 169 bits (428), Expect = 4e-42
Identities = 106/292 (36%), Positives = 149/292 (50%), Gaps = 15/292 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y L +G G YG V A R RV A+KK + RE+ LL+ + +N
Sbjct: 35 YINLTPIGTGAYGTVCAAECTRSGTRV-AIKKFNRPFQSIIHARRTYRELRLLRCMCHEN 93
Query: 67 IVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
I+ L D+ +D +Y V + DL +I K Q L + I+ + Q+ +G+
Sbjct: 94 IIDLLDVFTPNENVNDIEDVYFVSMLMGADLS----NILKIQRLNDDHIQFLVYQILRGL 149
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y H+ IIHRDLKP N+ +N D LK+ DFGLAR + Y + T WYRAPE++L
Sbjct: 150 KYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGY---VATRWYRAPEIML 206
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII--YL 239
Y+ VDVWS+GCI AE+ K LF G IDQ+ +I V GTP+E I
Sbjct: 207 NWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEA 266
Query: 240 PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
++ PK RR+ + IDLL+K++ DP R +AK A++H Y
Sbjct: 267 RNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEY 318
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 168 bits (426), Expect = 7e-42
Identities = 103/308 (33%), Positives = 171/308 (55%), Gaps = 31/308 (10%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
+ Y L+ +G G G+V+ AVD RV A+KKI L D A+REI +++ L
Sbjct: 18 SRYMDLKPLGCGGNGLVFSAVDNDCDKRV-AIKKIVLT--DPQSVKHALREIKIIRRLDH 74
Query: 65 DNIVRLYDIVH-------------SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIK 111
DNIV++++I+ ++ + +Y+V E+++ DL +E PL +
Sbjct: 75 DNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ----GPLLEEHAR 130
Query: 112 KFMMQLCKGIAYCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYTHE-- 168
FM QL +G+ Y H+ ++HRDLKP NL IN D LK+GDFGLAR Y+H+
Sbjct: 131 LFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPH---YSHKGH 187
Query: 169 ----IVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRV 224
+VT WYR+P +LL Y+ +D+W+ GCIFAEM K LF+G E++Q+ I
Sbjct: 188 LSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILES 247
Query: 225 LGTPNERTWPDII-YLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISA 283
+ +E +++ +P + + L++++P + +D L++++T+ P+ R++A
Sbjct: 248 IPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFSPMDRLTA 307
Query: 284 KRAVQHPY 291
+ A+ HPY
Sbjct: 308 EEALSHPY 315
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 168 bits (426), Expect = 7e-42
Identities = 90/242 (37%), Positives = 149/242 (61%), Gaps = 6/242 (2%)
Query: 53 IREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKK 112
+RE+ L+ + NIV+L +++ + LY VFE+++ +L + M+ + + IK
Sbjct: 14 LREVKSLRRMNHPNIVKLKEVIREN-DILYFVFEYMECNLYQLMKD--RQKLFAEADIKN 70
Query: 113 FMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTL 172
+ Q+ +G++Y H HRDLKP+NLL+++D +K+ DFGLAR +T + T
Sbjct: 71 WCFQVFQGLSYMHQRGYFHRDLKPENLLVSKD-IIKIADFGLAREVNSS-PPFTEYVSTR 128
Query: 173 WYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERT 232
WYRAPEVLL Y++ VD+W++G I AE+ + +P+F G SE D+I+KI V+GTP E T
Sbjct: 129 WYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICSVIGTPTEET 188
Query: 233 WPDIIYLPD-FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
W + + L + FP+ LS ++PS + I+L+++L ++DP R +A +QHP+
Sbjct: 189 WLEGLNLANTINYQFPQLPGVPLSSLMPSASEDAINLIERLCSWDPSSRPTAAEVLQHPF 248
Query: 292 FK 293
F+
Sbjct: 249 FQ 250
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 168 bits (426), Expect = 7e-42
Identities = 95/291 (32%), Positives = 159/291 (53%), Gaps = 17/291 (5%)
Query: 10 LEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 69
+ +G G G+V AV+ +V A+KKI ++ +REI LL+ + +N++
Sbjct: 78 IRPIGRGACGIVCAAVNSVTGEKV-AIKKIGNAFDNIIDAKRTLREIKLLRHMDHENVIT 136
Query: 70 LYDIVHSDAHKL----YLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
+ DIV + Y+V+E +D DL+R + S +Q L + + + QL +G+ Y H
Sbjct: 137 IKDIVRPPQRDIFNDVYIVYELMDTDLQRILRS---NQTLTSDQCRFLVYQLLRGLKYVH 193
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQ 185
+ I+HRDL+P N+L+N LK+GDFGLAR T +VT WYRAPE+LL +
Sbjct: 194 SANILHRDLRPSNVLLNSKNELKIGDFGLARTTS-DTDFMTEYVVTRWYRAPELLLNCSE 252
Query: 186 YSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPD---- 241
Y+ +D+WS+GCI E+ +PLF G + Q+ I ++G+P+ + + +L
Sbjct: 253 YTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSS---LGFLRSDNAR 309
Query: 242 -FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ P++ ++ + P + IDLL++++ +DP RIS A+ H Y
Sbjct: 310 RYVRQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRISVDEALGHAY 360
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 167 bits (423), Expect = 2e-41
Identities = 102/295 (34%), Positives = 155/295 (51%), Gaps = 15/295 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ L VG G YG V A D + RV A+KK+ + RE+ LLK +K +N
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRV-AVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 67 IVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
++ L D+ + + +YLV + DL +I K Q L + ++ + Q+ +G+
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLN----NIVKCQKLTDDHVQFLIYQILRGL 138
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y H+ IIHRDLKP NL +N D LK+ DFGLAR + Y + T WYRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGY---VATRWYRAPEIML 195
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII--YL 239
Y+ VD+WS+GCI AE+ + LF G IDQ+ I R++GTP I
Sbjct: 196 NWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESA 255
Query: 240 PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
++ + + + N + V + +DLL+K++ D RI+A +A+ H YF +
Sbjct: 256 RNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQ 310
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 167 bits (423), Expect = 2e-41
Identities = 93/290 (32%), Positives = 162/290 (55%), Gaps = 12/290 (4%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLES--EDEGVPSTAIREISLL 59
+ + NY+++ ++ G++G VY+ V + NRV A+K++ + G IRE+ +L
Sbjct: 21 NSIENYEKVCRISSGSFGNVYR-VRRKTDNRVFALKRMNPSMCYDTNGFSILYIREVMIL 79
Query: 60 KELKDDNIVRLYDIVHS-DAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
K ++ NI+ + ++V + + ++V E D DL+ + S+ K +G + Q+
Sbjct: 80 KHIRHRNIMEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVGK---IGMKAARFLTCQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
KG+ + H I+HRDLKP N+L+ RDG L++ DFGLARA + T+ +VTLWYR E
Sbjct: 137 KGLKFLHGAGIVHRDLKPSNILLMRDGGLRIADFGLARAIESQM---TNLVVTLWYRPIE 193
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
+LLG + Y +D+WS+GC+ EM +P+ +G+ E+DQ+ +IFR+LG P + + + +
Sbjct: 194 ILLGSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTDADF-EGLD 252
Query: 239 LPDFKT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
LP FK P + + L+++DP R +A + +
Sbjct: 253 LPHFKNIRRPSTFEASFEGDFECYGEEAASFVRNLLSFDPRKRCTASQGL 302
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 167 bits (422), Expect = 2e-41
Identities = 99/297 (33%), Positives = 158/297 (52%), Gaps = 19/297 (6%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQN--RVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
Y+ L KVGEG+YG V K +H+N ++VA+K I E ++ V A+REI LK+
Sbjct: 4 YETLGKVGEGSYGTVMKC---KHKNTGQIVAIK-IFYERPEQSVNKIAMREIKFLKQFHH 59
Query: 65 DNIVRLYDIVHSDAHKLYLVFEFLDL----DLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
+N+V L ++ K++LVFEF+D +L+ Y + + ++K++ Q+ +
Sbjct: 60 ENLVNLIEVFRQKK-KIHLVFEFIDHTVLDELQHYCHGLESKR------LRKYLFQILRA 112
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
I Y H++ IIHRD+KP+N+L+++ G KL DFG AR P YT + T WYRAPE++
Sbjct: 113 IDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELV 172
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLP 240
L Y VD+W++GC+ EM P S++D + KI +G + P
Sbjct: 173 LKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSP 232
Query: 241 DFK-TTFPK-WNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKEE 295
F P+ + +N + P L+ D++ + DP RIS+ + H YF +
Sbjct: 233 IFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRD 289
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 164 bits (416), Expect = 1e-40
Identities = 112/305 (36%), Positives = 164/305 (53%), Gaps = 24/305 (7%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E Y+ E VG+G+YGVV AVD H VA+KKI E + +REI LL+ L
Sbjct: 100 EANRYQIQEVVGKGSYGVVASAVD-SHTGERVAIKKINDVFEHVSDATRILREIKLLRLL 158
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
+ ++V + I+ + + +Y+VFE ++ DL + +++ + L + F+ QL
Sbjct: 159 RHPDVVEIKHIMLPPSRREFRDIYVVFELMESDLHQVIKA---NDDLTPEHYQFFLYQLL 215
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR-AFGVPLRA--YTHEIVTLWYR 175
+G+ Y HA + HRDLKP+N+L N D LK+ DFGLAR +F A +T + T WYR
Sbjct: 216 RGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYR 275
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
APE L G +Y+ +D+WS+GCIFAEM KPLF G + + Q+ + LGTP +
Sbjct: 276 APE-LCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESI 334
Query: 234 PDI------IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
I YL + P S P D + LL++L+ +DP R SA+ A+
Sbjct: 335 SRIRNEKARRYLSSMRKKQPV----PFSHKFPKADPLALRLLERLLAFDPKDRASAEDAL 390
Query: 288 QHPYF 292
PYF
Sbjct: 391 ADPYF 395
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 164 bits (415), Expect = 1e-40
Identities = 102/304 (33%), Positives = 166/304 (54%), Gaps = 28/304 (9%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRH-QNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++ ++++G G YG+V A ++ VA+KK+ + ++RE+ LL+ +
Sbjct: 23 FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 82
Query: 66 -NIVRLYD---IVHSDA--HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
NI LYD + + D + LYL E ++ D+ + ++S QPL + F Q+
Sbjct: 83 KNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKS---GQPLTDAHYQSFTYQILC 139
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGV-PL---RAYTHEIVTLWYR 175
G+ Y H+ ++HRDLKP NLL+N D LK+ DFGLAR + P+ + T + T WYR
Sbjct: 140 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYR 199
Query: 176 APEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW-- 233
APE++L + Y+ +DVWS GCI AE KP+F G ++Q+ +I +VLGTP + T
Sbjct: 200 APEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRR 259
Query: 234 ------PDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
D I+ F P N + P+ ++ +DLL++++ +DP RI+ A+
Sbjct: 260 IGSKNVQDYIHQLGFIPKVPFVN------LYPNANSQALDLLEQMLAFDPQKRITVDEAL 313
Query: 288 QHPY 291
+HPY
Sbjct: 314 EHPY 317
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 164 bits (415), Expect = 1e-40
Identities = 105/298 (35%), Positives = 154/298 (51%), Gaps = 21/298 (7%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ L VG G YG V A D + RV A+KK+ + RE+ LLK +K +N
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRV-AVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 67 IVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
++ L D+ + + +YLV + DL +I K Q L + ++ + Q+ +G+
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLN----NIVKCQKLTDDHVQFLIYQILRGL 138
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y H+ IIHRDLKP NL +N D LK+ DFGLAR + Y + T WYRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGY---VATRWYRAPEIML 195
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP-----NERTWPDI 236
Y+ VD+WS+GCI AE+ + LF G I+Q+ +I R+ GTP N +
Sbjct: 196 NWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEA 255
Query: 237 IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
T PK N N V + +DLL+K++ D RI+A +A+ H YF +
Sbjct: 256 RNYIQSLTQMPKMNFAN---VFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQ 310
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 162 bits (409), Expect = 7e-40
Identities = 90/227 (39%), Positives = 135/227 (58%), Gaps = 7/227 (3%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y++L K GEG+YGVV+K + + +VVA+KK +D V A+REI +LK+LK
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRN-KTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLK 59
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPK----DQPLGGNIIKKFMMQLCK 119
N+V L ++ K++LVFE+ D L +E P D +G +L
Sbjct: 60 HPNLVNLIEVFRRK-RKMHLVFEYCDHTLLNELERNPNGMDSDSIVGRLRSVADRSRLAP 118
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 179
+ IHRD+KP+N+LI + G +K+ DFG A+ +P AYT + T WYRAPE+
Sbjct: 119 KNNQIMILQCIHRDIKPENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPEL 177
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLG 226
L+G QY + VD+W+IGC+FAE+ +PL+ G S++DQ++ I R LG
Sbjct: 178 LVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLG 224
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 162 bits (409), Expect = 7e-40
Identities = 109/304 (35%), Positives = 165/304 (53%), Gaps = 22/304 (7%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E + Y+ E +G+G+YGVV A+D H VA+KKI E + +REI LL+ L
Sbjct: 122 EASRYQIQEVIGKGSYGVVASAIDT-HSGEKVAIKKINDVFEHVSDATRILREIKLLRLL 180
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
+ +IV + ++ + + +Y+VFE ++ DL + +++ + L + F+ QL
Sbjct: 181 RHPDIVEIKHVMLPPSRREFRDIYVVFELMESDLHQVIKA---NDDLTPEHYQFFLYQLL 237
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR-AFGVPLRA--YTHEIVTLWYR 175
+G+ + H + HRDLKP+N+L N D LK+ DFGLAR +F A +T + T WYR
Sbjct: 238 RGLKFIHTANVFHRDLKPKNILANSDCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYR 297
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
APE L G +Y+ +D+WSIGCIFAEM KPLF G + + Q+ + +LGTP
Sbjct: 298 APE-LCGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPPPEA- 355
Query: 234 PDIIYLPDFKTTFPKWNRRNLSEV-----IPSLDANGIDLLDKLITYDPIHRISAKRAVQ 288
I + + K N R V P +D + LL +L+ +DP R SA+ A+
Sbjct: 356 --IARIRNEKARRYLGNMRRKPPVPFTHKFPHVDPLALRLLHRLLAFDPKDRPSAEEALA 413
Query: 289 HPYF 292
PYF
Sbjct: 414 DPYF 417
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 162 bits (409), Expect = 7e-40
Identities = 111/305 (36%), Positives = 165/305 (53%), Gaps = 24/305 (7%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E Y+ E VG+G+YGVV A+D H VA+KKI + + +REI LL+ L
Sbjct: 86 EANRYQIQEVVGKGSYGVVGSAIDT-HTGERVAIKKINDVFDHISDATRILREIKLLRLL 144
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
++V + I+ + + +Y+VFE ++ DL + +++ + L + F+ QL
Sbjct: 145 LHPDVVEIKHIMLPPSRREFRDVYVVFELMESDLHQVIKA---NDDLTPEHHQFFLYQLL 201
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR-AFGVPLRA--YTHEIVTLWYR 175
+G+ Y HA + HRDLKP+N+L N D LK+ DFGLAR +F A +T + T WYR
Sbjct: 202 RGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYR 261
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
APE L G +Y+ +D+WS+GCIFAEM KPLF G + + Q+ + LGTP
Sbjct: 262 APE-LCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAI 320
Query: 234 PDI------IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
I YL + + P S+ P D + + LL++LI +DP R SA+ A+
Sbjct: 321 SKIRNDKARRYLGNMRKKQPV----PFSKKFPKADPSALRLLERLIAFDPKDRPSAEEAL 376
Query: 288 QHPYF 292
PYF
Sbjct: 377 ADPYF 381
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 162 bits (409), Expect = 7e-40
Identities = 105/293 (35%), Positives = 160/293 (53%), Gaps = 18/293 (6%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
+G G +GVV+ D R RV A+KK+ + RE+ +L K +N++ D
Sbjct: 46 IGYGAFGVVWAVTDPRDGRRV-ALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALD 104
Query: 73 IV---HSDA-HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHR 128
I+ H D ++Y++ E L DL + + S Q L + IK F+ Q+ +G+ Y H+ R
Sbjct: 105 ILQPPHLDFFQEIYVITELLQSDLHKIIVS---PQHLSADHIKVFLYQILRGLKYLHSAR 161
Query: 129 IIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAY-THEIVTLWYRAPEVLLGGKQYS 187
I+HRD+KP NLL+N + LK+ DFGLAR + T E+VT +YRAPE+L+G + YS
Sbjct: 162 ILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYS 221
Query: 188 TGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTTF- 246
+ VDVWS+GCIF E+ R+ LF + + Q+ I +LGTP T D+ + + T
Sbjct: 222 SAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTP---TMEDMRHACEGARTHM 278
Query: 247 ----PKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
PK ++ + S + LL +++ +DP RIS A+ HPY E
Sbjct: 279 LRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDE 331
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 161 bits (408), Expect = 9e-40
Identities = 108/311 (34%), Positives = 171/311 (54%), Gaps = 33/311 (10%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
+ YK ++ +GEG YG V A+ + VA+KKI+ S+ V T IREI LL+ +
Sbjct: 11 SQYKLVDLIGEGAYGTVCSAIH-KPSGIKVAIKKIQPFSKKLFVTRT-IREIKLLRYFHE 68
Query: 65 -DNIVRLYDIVH----SDAHKLYLVFEFLDLDLKRYMESIPKD-QPLGGNIIKKFMMQLC 118
+NI+ + D V + +YLV E ++ DL++ + + L + ++ F Q+
Sbjct: 69 HENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQIL 128
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA-------YTHEIVT 171
+ + H+ ++IHRD+KP NLL+N + +LK+ DFGLAR + T + T
Sbjct: 129 RALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVAT 188
Query: 172 LWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNER 231
WYRAPE++L ++Y+T +D+WS GCI AEM + KPLF G Q++ I VLGTP+
Sbjct: 189 RWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFE 248
Query: 232 TWPDI------IYLPDFKTTFP-----KWNRRNLSEVIPSLDANGIDLLDKLITYDPIHR 280
+ I Y+ + P W++ +L+ P + IDLLDK++ ++P R
Sbjct: 249 DFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLN---PDM----IDLLDKMLQFNPDKR 301
Query: 281 ISAKRAVQHPY 291
ISA A++HPY
Sbjct: 302 ISAAEALRHPY 312
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 161 bits (408), Expect = 9e-40
Identities = 107/306 (34%), Positives = 165/306 (52%), Gaps = 24/306 (7%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+ Y+ LE +G+G+YGVV A+D + +V A+KKI E +RE+ LL+ L
Sbjct: 9 DANRYRILEVIGKGSYGVVCAAIDTQTGEKV-AIKKINDVFEHVSDALRILREVKLLRLL 67
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
+ +IV + I+ + + +Y+VFE ++ DL + +++ + L + F+ Q+
Sbjct: 68 RHPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKA---NDDLTREHHQFFLYQML 124
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF--GVPLRAY-THEIVTLWYR 175
+ + Y H + HRDLKP+N+L N + LK+ DFGLAR P + T + T WYR
Sbjct: 125 RALKYMHTANVYHRDLKPKNILANANCKLKVCDFGLARVSFNDTPTTVFWTDYVATRWYR 184
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
APE L G +Y+ +D+WSIGCIFAE+ KPLF G S + Q+ I +LGTP T
Sbjct: 185 APE-LCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETI 243
Query: 234 PDI------IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
+ YL + + K N S+ P+ D + LL +L+ +DP R +A A+
Sbjct: 244 AGVRNEKARKYLNEMR----KKNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEAL 299
Query: 288 QHPYFK 293
PYFK
Sbjct: 300 ADPYFK 305
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 159 bits (403), Expect = 3e-39
Identities = 107/302 (35%), Positives = 161/302 (52%), Gaps = 16/302 (5%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+ Y+ LE +G+G+YGVV A+D H VA+KKI E +RE+ LL+ L
Sbjct: 9 DANRYRILEVIGKGSYGVVCAAIDT-HTGEKVAIKKINDVFEHISDALRILREVKLLRLL 67
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
+ +IV + I+ + + +Y+VFE ++ DL + +++ + L + F+ Q+
Sbjct: 68 RHPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKA---NDDLTREHHQFFLYQML 124
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR-AFG-VPLRAY-THEIVTLWYR 175
+ + + H + HRDLKP+N+L N + LK+ DFGLAR AF P + T + T WYR
Sbjct: 125 RALKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVFWTDYVATRWYR 184
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
APE L G +Y+ +DVWSIGCIFAE+ KPLF G S + Q+ I +LGTP T
Sbjct: 185 APE-LCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETI 243
Query: 234 PDI--IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ + T K N S+ D + LL +L+ +DP R + A+ PY
Sbjct: 244 SGVRNDKARKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADPY 303
Query: 292 FK 293
FK
Sbjct: 304 FK 305
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 159 bits (402), Expect = 5e-39
Identities = 105/308 (34%), Positives = 157/308 (50%), Gaps = 26/308 (8%)
Query: 7 YKRLEKVGEGTYGVVYKA-VDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
Y+ ++ +G+G YG V R +A+KKI E + AIRE+ + K
Sbjct: 38 YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGH 97
Query: 66 -NIVRLYD---IVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
NIV L D + S LY E +D DL + + S + L IK F+ Q+ G+
Sbjct: 98 KNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQ---LSEFHIKYFLYQILCGL 154
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA--------YTHEIVTLW 173
Y H+ +IHRDLKP N+L +G LK+ DFGLAR T+ + T W
Sbjct: 155 KYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRW 214
Query: 174 YRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
YRAPE+LL + YS VD+W++GCI AE RKP+F G + QIF+I +VLGTP++
Sbjct: 215 YRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDI- 273
Query: 234 PDIIYLPDFK-------TTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRA 286
+I K + P + + S + P I+L++ L+ +D HR++ ++A
Sbjct: 274 --LIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQA 331
Query: 287 VQHPYFKE 294
+ HP+ E
Sbjct: 332 ISHPFLNE 339
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 158 bits (400), Expect = 8e-39
Identities = 109/306 (35%), Positives = 165/306 (53%), Gaps = 24/306 (7%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E + Y+ E +G+G+YGVV A D H VA+KKI E + +REI LL+ L
Sbjct: 21 EGSRYRIEEVIGKGSYGVVCSAYDT-HTGEKVAIKKINDIFEHVSDATRILREIKLLRLL 79
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
+ +IV + I+ + + +Y+VFE ++ DL + +++ + L + F+ QL
Sbjct: 80 RHPDIVEIKHILLPPSRREFRDIYVVFELMESDLHQVIKA---NDDLTPEHYQFFLYQLL 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR-AFGVPLRA--YTHEIVTLWYR 175
+G+ Y H + HRDLKP+N+L N D LK+ DFGLAR AF A +T + T WYR
Sbjct: 137 RGLKYIHTANVFHRDLKPKNILANADCKLKICDFGLARVAFNDTPTAIFWTDYVATRWYR 196
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNE--- 230
APE L G +Y+ +D+WSIGCIFAE+ KPLF G + + Q+ + +LGTP+
Sbjct: 197 APE-LCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEAI 255
Query: 231 ---RTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
R YL + P S P D + LL+K+++++P R +A+ A+
Sbjct: 256 GRVRNEKARRYLSSMRKKKP----IPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEAL 311
Query: 288 QHPYFK 293
YFK
Sbjct: 312 ADVYFK 317
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 156 bits (394), Expect = 4e-38
Identities = 106/306 (34%), Positives = 161/306 (51%), Gaps = 24/306 (7%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
E + Y+ E VG+G+YGVV A + H VA+KK+ E +REI LL+ L
Sbjct: 12 EASQYQIQEVVGKGSYGVVASA-ECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLL 70
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
+ +IV + I+ K +Y+VFE ++ DL ++ + L + F+ QL
Sbjct: 71 RHPDIVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKV---NDDLTPQHHQFFLYQLL 127
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRA---YTHEIVTLWYR 175
+G+ + H+ + HRDLKP+N+L N D +K+ D GLAR + +T + T WYR
Sbjct: 128 RGLKFMHSAHVFHRDLKPKNILANADCKIKICDLGLARVSFTDSPSAVFWTDYVATRWYR 187
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
APE L G Y+ +D+WS+GCIFAEM KPLF G + + Q+ + +LGTP+ T
Sbjct: 188 APE-LCGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPITL 246
Query: 234 PDI------IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAV 287
I YL + + P + P++D + LL +LI +DP R SA+ A+
Sbjct: 247 SRIRNEKARKYLGNMRRKDPV----PFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEAL 302
Query: 288 QHPYFK 293
PYF+
Sbjct: 303 ADPYFQ 308
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 155 bits (392), Expect = 7e-38
Identities = 105/302 (34%), Positives = 167/302 (54%), Gaps = 16/302 (5%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
+ +K E +G+G+YGVV A+D +V A+KKI E + +REI LL+ L
Sbjct: 9 DANRFKVQEVIGKGSYGVVCSAIDTLTGEKV-AIKKIHDIFEHISDAARILREIKLLRLL 67
Query: 63 KDDNIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
+ +IV + I+ + + +Y+VFE ++ DL + +++ + L + F+ QL
Sbjct: 68 RHPDIVEIKHIMLPPSRREFKDIYVVFELMESDLHQVIKA---NDDLTREHYQFFLYQLL 124
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLAR-AFG-VPLRAY-THEIVTLWYR 175
+ + Y H + HRDLKP+N+L N + LK+ DFGLAR AF P + T + T WYR
Sbjct: 125 RALKYIHTANVYHRDLKPKNILANANCKLKICDFGLARVAFNDTPTTIFWTDYVATRWYR 184
Query: 176 APEVLLGG--KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTW 233
APE L G +Y+ +D+WSIGCIFAE+ KPLF G + + Q+ + +LGTP+ T
Sbjct: 185 APE-LCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTI 243
Query: 234 PDI--IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ + T+ K ++ P+ D + LL++L+ +DP R +A+ A+ PY
Sbjct: 244 SRVRNEKARRYLTSMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEALADPY 303
Query: 292 FK 293
FK
Sbjct: 304 FK 305
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 155 bits (391), Expect = 9e-38
Identities = 101/299 (33%), Positives = 154/299 (50%), Gaps = 33/299 (11%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
S + Y+ ++ G G +G+V A D RV A+K+I + + + + REIS L+
Sbjct: 3 SSIYRYETIQVAGRGAFGLVVIARDTLTSKRV-AIKRIMVPNVSK---VSLAREISCLRN 58
Query: 62 LKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
L NI++L D F DL M + ++ P + Q+ GI
Sbjct: 59 LHHRNILKLLDC-------------FPSADL---MSIVTEEVPYTW-----YYTQILSGI 97
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGV--PLRAYTHEIVTLWYRAPEV 179
AY H+ I+HRD+KP+N+L+ +K+ DFG A + P + Y + T WYRAPE+
Sbjct: 98 AYLHSKEIMHRDIKPENILVTSRNVVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPEL 157
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
L G K+Y VD+W+IGCI AE+ KP+F G SE++QI IF VLGTPNE WP+ +
Sbjct: 158 LFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNEDNWPNWRTM 217
Query: 240 PDFKTTF--PKWNRRNLSEVI--PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
PD PK R N +E++ + N + L + + R+ A ++ P+ K+
Sbjct: 218 PDANKLLFEPKEPRNNWTEILLCKEISNNFTEFLGSHLQF--FKRLKASELLKEPWIKQ 274
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 154 bits (389), Expect = 1e-37
Identities = 90/235 (38%), Positives = 136/235 (57%), Gaps = 10/235 (4%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y+ +++VGEG +G VYK+ V A+KK+ ++ E G P TAIREI L K +
Sbjct: 1 MEKYENIKQVGEGAFGQVYKS-RRTSDGAVFAIKKMPVDRET-GFPFTAIREIKLCKSVI 58
Query: 64 DDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
+ +I+ L +IV + +++V E++ DL + S K L + I+ QL + ++
Sbjct: 59 NKHIIGLDEIVFEEGF-IFVVLEYMPYDLTGLLASGAK---LSTDQIRSITSQLIEAVSS 114
Query: 124 CHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
H ++HRD+KP N+L++ G LKL DFGL R + T+ + TLWYRAPE+LLG
Sbjct: 115 MHGMGLVHRDIKPSNILLDCHGMLKLTDFGLTREISGMM---TNRVCTLWYRAPELLLGE 171
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNER-TWPDII 237
YS VD WS+GCI EM +P + G E+ QI IF LG P ++ W D++
Sbjct: 172 TSYSLKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQDKYKWSDLL 226
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 152 bits (384), Expect = 6e-37
Identities = 99/298 (33%), Positives = 161/298 (53%), Gaps = 19/298 (6%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y+ +G G++GVV +A L +A+K++ + + RE+ +++ +
Sbjct: 24 SYEPCRVLGSGSFGVVIQA-KLVGTPGFIAVKRVLQDKRYKN------RELQIMRAISHP 76
Query: 66 NIVRLYDIVHS-----DAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNI-IKKFMMQLCK 119
NI++L H+ D L L+ E++ + M + + N+ IK + QL +
Sbjct: 77 NIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFR 136
Query: 120 GIAYCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+AY H+ + HRD+KPQNLL++ + G LKL DFG A+ VP I + +YRAPE
Sbjct: 137 ALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVL-VPSEPNVSYICSRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
++ G Y+T +DVWS C+ AE+ +PLF GDS ++Q+ +I RVLGTP+ +
Sbjct: 196 LVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEIS--VM 253
Query: 239 LPDF-KTTFPKWNRRNLSEVIP-SLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P++ + P L V+P + N +DLL K++TY P RISA + HP+F E
Sbjct: 254 NPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDE 311
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 152 bits (383), Expect = 7e-37
Identities = 91/296 (30%), Positives = 159/296 (52%), Gaps = 22/296 (7%)
Query: 12 KVGEGTYGVVYKAVDLRHQNRV-VAMKKIRLESEDEGVPSTAIREISLLKELKDD-NIVR 69
K+G G++ ++ + VA++KI ++ +RE+ LL+ L+ NIV
Sbjct: 28 KIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVW 87
Query: 70 LYDI-----VHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
L+D + + +YL E ++ DL + + S +Q L + F+ Q+ + Y
Sbjct: 88 LFDTDIVFYPNGALNGVYLYEELMECDLSQIIRS---EQRLEDAHFQSFIYQILCALKYI 144
Query: 125 HAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVP-------LRAYTHEIVTLWYRAP 177
H+ ++H DLKP+NLL+N D LK+ +FGL+ ++ ++ Y I ++WY+AP
Sbjct: 145 HSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGY---ITSIWYKAP 201
Query: 178 EVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
E+LL ++ + VD+WS GCI AE+ RKP+F G +D + I ++LGTP E T +I
Sbjct: 202 EILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIA 261
Query: 238 YLPDFKTTFPKWN--RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ F N R+ ++P + ++LL K++ +DP RI+ + A++HPY
Sbjct: 262 SQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPY 317
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 151 bits (382), Expect = 9e-37
Identities = 84/232 (36%), Positives = 139/232 (59%), Gaps = 9/232 (3%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREI-SLLKELKDD 65
Y + KVG+GT+G VY A VVA+K ++ + +T +RE+ SLL+ +++
Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVS-DATRLREVHSLLRLSENE 94
Query: 66 NIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCH 125
NIV ++D+ L++V EFLD +L + + S K+ PL ++ M Q+ KG+ + H
Sbjct: 95 NIVNIFDLYIDQFRCLHIVMEFLDCNLYQLI-STRKNDPLTLEQVQDIMRQIFKGLNHIH 153
Query: 126 AHRIIHRDLKPQNLLINRDG-----NLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
+ HRD+KP+N+LI+ + N+K+ DFGLAR YT + T WYRAPE+L
Sbjct: 154 TNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREIN-SRPPYTEYVSTRWYRAPELL 212
Query: 181 LGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERT 232
L YS VD+++ GC+ E+ +P+F G+ + DQ++K+ +LG+P+E++
Sbjct: 213 LRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQS 264
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 151 bits (382), Expect = 9e-37
Identities = 97/298 (32%), Positives = 160/298 (53%), Gaps = 25/298 (8%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
+ L+ +G G++G VYKAV LR + +A+KKI+++ + RE++++ E+ N
Sbjct: 37 FTNLQLIGTGSFGAVYKAV-LRENDEPIAIKKIKVDDRFKS------RELTIMHEMDHPN 89
Query: 67 IVRL-YDIVHSDAHKLYLVFEFLDLDLKR-YMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
I+RL Y V + L V EF+ DL + + D+ + IK +M QL +GI +
Sbjct: 90 IIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIKLYMFQLLRGIGFL 149
Query: 125 HAHRIIHRDLKPQNLLINR-DGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGG 183
H H I+HRD+KP+NLL++ +G LK+ DFG A+ T+ I + +YRAPE++ G
Sbjct: 150 HLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITY-ICSRYYRAPELIFGS 208
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWP----DIIYL 239
K Y T +D WS+G + E+ + P+F DS +D + + GTP++ + +++
Sbjct: 209 KNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAKWNYEYVHI 268
Query: 240 PDFKTT---FPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P T K+ R LS + ++LL+ L+ DP RI A+ PYF +
Sbjct: 269 PYDTITGVGIQKFIGRKLS-------LSTLELLNSLMKMDPKLRIKPYEALTLPYFDD 319
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 151 bits (381), Expect = 1e-36
Identities = 102/298 (34%), Positives = 160/298 (53%), Gaps = 19/298 (6%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y + +G G++GVV+ A L N +VA+KK+ + + RE+ ++++L
Sbjct: 35 SYYDQKVIGNGSFGVVFLA-KLSTTNEMVAIKKVLQDKRFKN------RELQIMRKLNHP 87
Query: 66 NIVRLYDIVHSDAHK-----LYLVFEFLDLDLKRYMESIPKD-QPLGGNIIKKFMMQLCK 119
NIV+L +S K L L+ E++ + R K Q + +K +M QL +
Sbjct: 88 NIVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLR 147
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+AY H+ I HRD+KPQNLLI+ + G LKL DFG A+ + V I + +YRAPE
Sbjct: 148 SLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAK-YLVRNEPNVSYICSRYYRAPE 206
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
++ G Y+ +DVWS G + AE+ +P+F GDS +DQ+ +I +VLGTP +
Sbjct: 207 LIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSM-- 264
Query: 239 LPDFKT-TFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P++K FP+ ++V A IDL+ K+I Y P R + + A QH +F E
Sbjct: 265 NPNYKEFKFPQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSRPTPQAACQHAFFDE 322
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 150 bits (378), Expect = 3e-36
Identities = 98/298 (32%), Positives = 163/298 (53%), Gaps = 20/298 (6%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
++ E VG G++GVV+ V ++ N VA+KK+ + + RE+ ++K L
Sbjct: 38 SFPTTEVVGHGSFGVVFATV-IQETNEKVAIKKVLQDKRFKN------RELEIMKMLSHI 90
Query: 66 NIVRL----YDIVHSDAHKLYLVFEFLDLDL-KRYMESIPKDQPLGGNIIKKFMMQLCKG 120
NI+ L Y+ D L L+ E++ L +R + + P+ IK +M QL K
Sbjct: 91 NIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKS 150
Query: 121 IAYCHAH-RIIHRDLKPQNLLINRDG-NLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+ Y H + HRD+KPQNLL++ + +LKL DFG A+ P I + +YRAPE
Sbjct: 151 LNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLK-PTEPNVSYICSRYYRAPE 209
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
++ G Y+ +D+WS GC+ AE+ +P+F G+S IDQ+ +I ++LGTP+++ +I
Sbjct: 210 LIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQ---EICS 266
Query: 239 L-PDF-KTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ P++ + FP+ LS V D ++ L ++ YDP+ R +A + + PYF E
Sbjct: 267 MNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDE 324
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 150 bits (378), Expect = 3e-36
Identities = 102/300 (34%), Positives = 165/300 (55%), Gaps = 23/300 (7%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y + VG G++GVV + V L + A+K++ + + RE+ +++ +K
Sbjct: 31 SYTSSKVVGSGSFGVVMQ-VHLIESDSKAAIKRVLQDKRFKN------RELQIMRIMKHP 83
Query: 66 NIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNI-IKKFMMQLCK 119
NIV L + SD L LV EF+ + R + + + +K ++ QL +
Sbjct: 84 NIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLR 143
Query: 120 GIAYCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRA 176
+AY HA I HRD+KPQNLL++ +G LKL DFG A+ G P +Y I + +YRA
Sbjct: 144 SLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVSY---ICSRYYRA 200
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE++ G Y+ +D+WS GC+ AE+ PLF G+S IDQ+ +I ++LGTP+ +
Sbjct: 201 PELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTM 260
Query: 237 IYLPDF-KTTFPKWNRRNLSEVIP-SLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P++ + FP+ + LS V S+ + +DLL K++ Y P R++A A+ HP+F E
Sbjct: 261 --NPNYMEHRFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDE 318
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 150 bits (378), Expect = 3e-36
Identities = 107/306 (34%), Positives = 155/306 (49%), Gaps = 26/306 (8%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y+ L+ +G G G+V A D +R VA+KK+ +++ A RE+ L+K +
Sbjct: 61 LKRYQNLKPIGSGAQGIVCAAYDAV-LDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 119
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + ++ L + + Q+
Sbjct: 120 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-----MELDHERMSYLLYQML 174
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPE
Sbjct: 175 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 233
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP----NERTWP 234
V+L G Y VD+WS+GCI EM K LF G IDQ K+ LGTP ++ P
Sbjct: 234 VIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 292
Query: 235 DIIYLPDFK-----TTFPKWNRRNL----SEVIPSLDANGIDLLDKLITYDPIHRISAKR 285
+ + + TFPK +L SE + DLL K++ DP RIS
Sbjct: 293 TVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDD 352
Query: 286 AVQHPY 291
A+QHPY
Sbjct: 353 ALQHPY 358
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 150 bits (378), Expect = 3e-36
Identities = 107/306 (34%), Positives = 155/306 (49%), Gaps = 26/306 (8%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y+ L+ +G G G+V A D +R VA+KK+ +++ A RE+ L+K +
Sbjct: 61 LKRYQNLKPIGSGAQGIVCAAYDAV-LDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 119
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + ++ L + + Q+
Sbjct: 120 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-----MELDHERMSYLLYQML 174
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPE
Sbjct: 175 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 233
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP----NERTWP 234
V+L G Y VD+WS+GCI EM K LF G IDQ K+ LGTP ++ P
Sbjct: 234 VIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 292
Query: 235 DIIYLPDFK-----TTFPKWNRRNL----SEVIPSLDANGIDLLDKLITYDPIHRISAKR 285
+ + + TFPK +L SE + DLL K++ DP RIS
Sbjct: 293 TVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDD 352
Query: 286 AVQHPY 291
A+QHPY
Sbjct: 353 ALQHPY 358
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 150 bits (378), Expect = 3e-36
Identities = 107/306 (34%), Positives = 155/306 (49%), Gaps = 26/306 (8%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y+ L+ +G G G+V A D +R VA+KK+ +++ A RE+ L+K +
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAV-LDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + ++ L + + Q+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP----NERTWP 234
V+L G Y VD+WS+GCI EM K LF G IDQ K+ LGTP ++ P
Sbjct: 196 VIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 254
Query: 235 DIIYLPDFK-----TTFPKWNRRNL----SEVIPSLDANGIDLLDKLITYDPIHRISAKR 285
+ + + TFPK +L SE + DLL K++ DP RIS
Sbjct: 255 TVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDD 314
Query: 286 AVQHPY 291
A+QHPY
Sbjct: 315 ALQHPY 320
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 149 bits (377), Expect = 4e-36
Identities = 102/304 (33%), Positives = 162/304 (52%), Gaps = 23/304 (7%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
S+ Y ++ +G G++GVVY+A L +VA+KK+ + + RE+ ++++
Sbjct: 114 SQEVAYTDIKVIGNGSFGVVYQA-RLAETRELVAIKKVLQDKRFKN------RELQIMRK 166
Query: 62 LKDDNIVRLYDIVHSDAHK-----LYLVFEFLDLDLKRYMESIPKDQ-PLGGNIIKKFMM 115
L NIVRL +S K L LV E++ + R K + + +K +M
Sbjct: 167 LDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMY 226
Query: 116 QLCKGIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAF--GVPLRAYTHEIVTL 172
QL + +AY H+ + HRD+KPQNLL++ D LKL DFG A+ G P +Y I +
Sbjct: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSY---ICSR 283
Query: 173 WYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERT 232
+YRAPE++ G Y++ +DVWS GC+ AE+ +P+F GDS +DQ+ +I +VLGTP
Sbjct: 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQ 343
Query: 233 WPDIIYLPDF-KTTFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHP 290
++ P++ + FP+ ++V S I L L+ Y P R+S A H
Sbjct: 344 IREM--NPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHS 401
Query: 291 YFKE 294
+F E
Sbjct: 402 FFDE 405
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 149 bits (377), Expect = 4e-36
Identities = 102/304 (33%), Positives = 162/304 (52%), Gaps = 23/304 (7%)
Query: 2 SELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKE 61
S+ Y ++ +G G++GVVY+A L +VA+KK+ + + RE+ ++++
Sbjct: 114 SQEVAYTDIKVIGNGSFGVVYQA-RLAETRELVAIKKVLQDKRFKN------RELQIMRK 166
Query: 62 LKDDNIVRLYDIVHSDAHK-----LYLVFEFLDLDLKRYMESIPKDQ-PLGGNIIKKFMM 115
L NIVRL +S K L LV E++ + R K + + +K +M
Sbjct: 167 LDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMY 226
Query: 116 QLCKGIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAF--GVPLRAYTHEIVTL 172
QL + +AY H+ + HRD+KPQNLL++ D LKL DFG A+ G P +Y I +
Sbjct: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSY---ICSR 283
Query: 173 WYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERT 232
+YRAPE++ G Y++ +DVWS GC+ AE+ +P+F GDS +DQ+ +I +VLGTP
Sbjct: 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQ 343
Query: 233 WPDIIYLPDF-KTTFPKWNRRNLSEVIPS-LDANGIDLLDKLITYDPIHRISAKRAVQHP 290
++ P++ + FP+ ++V S I L L+ Y P R+S A H
Sbjct: 344 IREM--NPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHS 401
Query: 291 YFKE 294
+F E
Sbjct: 402 FFDE 405
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 149 bits (376), Expect = 5e-36
Identities = 107/310 (34%), Positives = 151/310 (48%), Gaps = 34/310 (10%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y++L+ +G G G+V A D V A+KK+ +++ A RE+ LLK +
Sbjct: 23 LKRYQQLKPIGSGAQGIVCAAFDTVLGINV-AVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + + L + + Q+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMM-TPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP---------- 228
V+LG Y VD+WS+GCI AEM K LF G IDQ K+ LGTP
Sbjct: 196 VILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 229 -------NERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
N +P I F+ FP W + SE + DLL K++ DP RI
Sbjct: 255 TVRNYVENRPKYPGI----KFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRI 310
Query: 282 SAKRAVQHPY 291
S A++HPY
Sbjct: 311 SVDEALRHPY 320
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 149 bits (376), Expect = 5e-36
Identities = 107/310 (34%), Positives = 151/310 (48%), Gaps = 34/310 (10%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y++L+ +G G G+V A D V A+KK+ +++ A RE+ LLK +
Sbjct: 23 LKRYQQLKPIGSGAQGIVCAAFDTVLGINV-AVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + + L + + Q+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMM-TPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP---------- 228
V+LG Y VD+WS+GCI AEM K LF G IDQ K+ LGTP
Sbjct: 196 VILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 229 -------NERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
N +P I F+ FP W + SE + DLL K++ DP RI
Sbjct: 255 TVRNYVENRPKYPGI----KFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRI 310
Query: 282 SAKRAVQHPY 291
S A++HPY
Sbjct: 311 SVDEALRHPY 320
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 149 bits (375), Expect = 6e-36
Identities = 101/300 (33%), Positives = 161/300 (53%), Gaps = 23/300 (7%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y + +G G++GVVY+A L +VA+KK+ + + RE+ ++++L
Sbjct: 55 SYTDTKVIGNGSFGVVYQA-KLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDHC 107
Query: 66 NIVRLYDIVHSDAHK-----LYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCK 119
NIVRL +S K L LV +++ + R + Q L +K +M QL +
Sbjct: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFR 167
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRA 176
+AY H+ I HRD+KPQNLL++ D LKL DFG A+ G P +Y I + +YRA
Sbjct: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY---ICSRYYRA 224
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE++ G Y++ +DVWS GC+ AE+ +P+F GDS +DQ+ +I +VLGTP ++
Sbjct: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM 284
Query: 237 IYLPDF-KTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P++ + FP+ ++V P I L +L+ Y P R++ A H +F E
Sbjct: 285 --NPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE 342
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 149 bits (375), Expect = 6e-36
Identities = 87/227 (38%), Positives = 125/227 (54%), Gaps = 13/227 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ L VG G YG V A D + RV A+KK+ + RE+ LLK +K +N
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRV-AVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 67 IVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
++ L D+ + + +YLV + DL +I K Q L + ++ + Q+ +G+
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLN----NIVKCQKLTDDHVQFLIYQILRGL 138
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y H+ IIHRDLKP NL +N D LK+ DFGLAR + Y + T WYRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGY---VATRWYRAPEIML 195
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP 228
Y+ VD+WS+GCI AE+ + LF G IDQ+ I R++GTP
Sbjct: 196 NWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 149 bits (375), Expect = 6e-36
Identities = 87/227 (38%), Positives = 125/227 (54%), Gaps = 13/227 (5%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ L VG G YG V A D + RV A+KK+ + RE+ LLK +K +N
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRV-AVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 67 IVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
++ L D+ + + +YLV + DL +I K Q L + ++ + Q+ +G+
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLN----NIVKCQKLTDDHVQFLIYQILRGL 138
Query: 122 AYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
Y H+ IIHRDLKP NL +N D LK+ DFGLAR + Y + T WYRAPE++L
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGY---VATRWYRAPEIML 195
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP 228
Y+ VD+WS+GCI AE+ + LF G IDQ+ I R++GTP
Sbjct: 196 NWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 149 bits (375), Expect = 6e-36
Identities = 100/300 (33%), Positives = 164/300 (54%), Gaps = 23/300 (7%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y + +G G++GVV++A L +VA+KK+ + + RE+ ++++L+
Sbjct: 547 SYTDTKVIGNGSFGVVFQA-KLCDTGELVAIKKVLQDRRFKN------RELQIMRKLEHC 599
Query: 66 NIVRLYDIVHSDAHK-----LYLVFEFLDLDLKRYMESIPKD-QPLGGNIIKKFMMQLCK 119
NIV+L +S K L LV E++ + + K Q + N I+ +M QL +
Sbjct: 600 NIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFR 659
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRA 176
+AY H+ I HRD+KPQNLL++ + LKL DFG A+ G P +Y I + +YRA
Sbjct: 660 SLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSY---ICSRYYRA 716
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE++ G Y+T +DVWS GC+ AE+ +P+F GDS +DQ+ ++ +VLGTP ++
Sbjct: 717 PELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREM 776
Query: 237 IYLPDF-KTTFPKWNRRNLSEVIP-SLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P++ + FP+ +V I+L+ L+ Y P RI+ +A HP+F E
Sbjct: 777 --NPNYTEFKFPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDE 834
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 148 bits (373), Expect = 1e-35
Identities = 93/248 (37%), Positives = 135/248 (53%), Gaps = 28/248 (11%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD- 65
Y ++G+G YG+V+KAVD R VVA+KKI D+ REI+LL+E D
Sbjct: 13 YLLRRQLGQGAYGIVWKAVD-RRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHP 71
Query: 66 NIVRLYDIVHSDAHK-LYLVFEFL-----------------DLDLKRYMESIPKDQPLGG 107
NI+ L D++ ++ + +YLVFEF+ D DL I K L
Sbjct: 72 NIISLLDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAV---IRKGGLLQD 128
Query: 108 NIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFG-VPL---- 162
++ QL + + H+ ++HRD KP N+L++ + +KL DFGLAR+ G +P
Sbjct: 129 VHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPED 188
Query: 163 RAYTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIF 222
+A T + T WYRAPEVLL +Y+ GVD+WS+GCI EM +PLF G S + Q+ I
Sbjct: 189 QAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELIL 248
Query: 223 RVLGTPNE 230
+ P+E
Sbjct: 249 ETIPPPSE 256
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 147 bits (371), Expect = 2e-35
Identities = 99/309 (32%), Positives = 156/309 (50%), Gaps = 23/309 (7%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ + +G G +G+V +AV+ N+ VA+KK+ S + +REI +L+ + N
Sbjct: 82 YEPTQNIGSGAFGIVCEAVETS-SNQKVAIKKVAHASATPTLARRTLREIRVLRYINHPN 140
Query: 67 IVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESI-PKDQPLGGNIIKKFMMQLCKGIAYCH 125
IV L DI + VF +DL I + PL + I F+ QL +G+ Y H
Sbjct: 141 IVPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLH 200
Query: 126 AHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAY---------THEIVTLWYRA 176
A I HRDLKP NLL+N+DG L++ DFG+A+ + + T + TL YRA
Sbjct: 201 AACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHVATLPYRA 260
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE+L ++ST VD+W++GCIF EM R + G S QI + +LG P + ++
Sbjct: 261 PELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPPQEVINEV 320
Query: 237 ------IYLPDF-KTTFPKWN-----RRNLSEVIPSLDANGIDLLDKLITYDPIHRISAK 284
+ DF + +W+ + + I + + ID + +L YD RI+ +
Sbjct: 321 RCDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVKQLFQYDAQKRINIQ 380
Query: 285 RAVQHPYFK 293
A+ HPY +
Sbjct: 381 DALLHPYIQ 389
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 147 bits (371), Expect = 2e-35
Identities = 105/342 (30%), Positives = 158/342 (45%), Gaps = 63/342 (18%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y L+ +GEG YGVV A + VA+KK + RE+ LL+ L+ DN
Sbjct: 49 YNSLKPLGEGAYGVVCTA-EYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDN 107
Query: 67 IVRLYDIV--HSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYC 124
++ + D+ DA L V+ F+ + + +++I K Q L I+ + Q+ +G+ Y
Sbjct: 108 VLEMIDVFTPDPDASSLNNVY-FVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYM 166
Query: 125 -----------------------------HAHRIIHRDLKPQNLLINRDGNLKLG----- 150
H+ IIHRDLKP N+ +N +K+
Sbjct: 167 SHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQ 226
Query: 151 ------------DFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCI 198
DFGLARA + Y + T WYRAPE++L Y+ VDVWS+GCI
Sbjct: 227 LSFLILSFFKILDFGLARAQDAEMTGY---VATRWYRAPEIMLNWMHYTQTVDVWSVGCI 283
Query: 199 FAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI------IYLPDFKTTFPKWNRR 252
AE+ + +PLF GD IDQ+ KI V+GTP E W I Y+ + R+
Sbjct: 284 LAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNRSPII----RQ 339
Query: 253 NLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ + P ++LL+ ++ DP RIS A++H Y +E
Sbjct: 340 DFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDYLRE 381
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 146 bits (369), Expect = 3e-35
Identities = 106/304 (34%), Positives = 156/304 (50%), Gaps = 22/304 (7%)
Query: 10 LEKVGEGTYGVVYK--AVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNI 67
+E +G G++G V K AV R VA+KK+R D RE LL+ ++ DNI
Sbjct: 121 IEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNI 180
Query: 68 VRLYDIV----HSDAHKLYLVFEFLDLDLKRYMESIPKD---QPLGGNIIKKFMMQLCKG 120
+ DI +D +Y+V EF L + ++ +D + L IK + Q+ +
Sbjct: 181 ICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQ-QRDYGRRVLTDEHIKFIIYQIIRA 239
Query: 121 IAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVL 180
+ Y H+ IIHRDLKP NL + D +L + DFGLAR+ + T + T WYR+PEV+
Sbjct: 240 LKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTSLTQYVQTRWYRSPEVI 299
Query: 181 LGG-KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI--- 236
Y+ D+WS+GCI AE+ +PLF GD Q +I ++ G+P+E I
Sbjct: 300 YWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIEND 359
Query: 237 --IYLPDFKTTFPKWNRRNLSEVI----PSLDANGIDLLDKLITYDPIHRISAKRAVQHP 290
+ ++ RRN +V PS D IDLL+KL+ DP RI+ + A+QHP
Sbjct: 360 NSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDF--IDLLEKLLVLDPEKRITVEEAIQHP 417
Query: 291 YFKE 294
Y E
Sbjct: 418 YLAE 421
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 146 bits (368), Expect = 4e-35
Identities = 89/250 (35%), Positives = 139/250 (55%), Gaps = 12/250 (4%)
Query: 54 REISLLKELKDDNIVRLYDIVHS-----DAHKLYLVFEFLDLDLKRYMESIPKDQPLGGN 108
RE+ +++ + NI++L H+ D L L+ E++ + M + + N
Sbjct: 34 RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPN 93
Query: 109 I-IKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYT 166
+ IK + QL + +AY H+ + HRD+KPQNLL++ + G LKL DFG A+ VP
Sbjct: 94 LSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVL-VPSEPNV 152
Query: 167 HEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLG 226
I + +YRAPE++ G Y+T +DVWS C+ AE+ +PLF GDS ++Q+ +I RVLG
Sbjct: 153 SYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLG 212
Query: 227 TPNERTWPDIIYLPDF-KTTFPKWNRRNLSEVIP-SLDANGIDLLDKLITYDPIHRISAK 284
TP+ + P++ + P L V+P + N +DLL K++TY P RISA
Sbjct: 213 TPSYHEIS--VMNPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAI 270
Query: 285 RAVQHPYFKE 294
+ HP+F E
Sbjct: 271 EVLTHPFFDE 280
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 146 bits (368), Expect = 4e-35
Identities = 99/300 (33%), Positives = 153/300 (51%), Gaps = 37/300 (12%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRL-- 70
VG G++G+V++A R VVA+KK+ + + RE+ +++ L N+V L
Sbjct: 88 VGTGSFGMVFQA-KCRETGEVVAIKKVLQDKRYKN------RELQIMQMLDHPNVVCLKH 140
Query: 71 --YDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNI-IKKFMMQLCKGIAYCH-A 126
Y ++ L LV EF+ + R S + L I +K + Q+C+G+AY H
Sbjct: 141 SFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLAYLHNC 200
Query: 127 HRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRAPEVLLGG 183
+ HRD+KPQNLL+N LK+ DFG A+ G P +Y I + +YRAPE++ G
Sbjct: 201 CGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISY---ICSRYYRAPELIFGA 257
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
+Y+T +D+WS GC+ AE+ +PLF G+S +DQ+ +I +VLGTP + K
Sbjct: 258 TEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTRE---------EIK 308
Query: 244 TTFPKWNRRNLSEVIP---------SLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P + ++ P L +DLL + Y P R +A A HP+F E
Sbjct: 309 CMNPNYTEFKFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDE 368
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 145 bits (365), Expect = 9e-35
Identities = 95/300 (31%), Positives = 163/300 (53%), Gaps = 26/300 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y+ + K+G G Y V++A+++ + RVV KI + + + RE+ +L+ L+
Sbjct: 39 DYQLVRKLGRGKYSEVFEAINITNNERVVV--KILKPVKKKKIK----REVKILENLRGG 92
Query: 66 -NIVRLYDIVHSDAHKL-YLVFEFLD-LDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
NI++L D V K LVFE+++ D K+ + + I+ +M +L K +
Sbjct: 93 TNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFD------IRFYMYELLKALD 146
Query: 123 YCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
YCH+ I+HRD+KP N++I+ + L+L D+GLA F P + Y + + +++ PE+L+
Sbjct: 147 YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLV 205
Query: 182 GGKQYSTGVDVWSIGCIFAEMC-NRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL- 239
+ Y +D+WS+GC+ A M R+P F G DQ+ +I +VLGT + ++
Sbjct: 206 DYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHID 265
Query: 240 --PDFKTTFPKWNRRNLSEVIPS-----LDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
P F + +R+ I S + +DLLDKL+ YD R++AK A++HPYF
Sbjct: 266 LDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 144 bits (364), Expect = 1e-34
Identities = 103/310 (33%), Positives = 149/310 (47%), Gaps = 34/310 (10%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y++L+ +G G G+V A D V A+KK+ +++ A RE+ LLK +
Sbjct: 23 LKRYQQLKPIGSGAQGIVCAAFDTVLGINV-AVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + + L + + Q+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP---------- 228
V+L G Y VD+WS+GCI E+ +F G IDQ K+ LGTP
Sbjct: 196 VIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 229 -------NERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
N +P I F+ FP W + SE + DLL K++ DP RI
Sbjct: 255 TVRNYVENRPKYPGI----KFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRI 310
Query: 282 SAKRAVQHPY 291
S A++HPY
Sbjct: 311 SVDEALRHPY 320
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 144 bits (364), Expect = 1e-34
Identities = 103/310 (33%), Positives = 149/310 (47%), Gaps = 34/310 (10%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y++L+ +G G G+V A D V A+KK+ +++ A RE+ LLK +
Sbjct: 23 LKRYQQLKPIGSGAQGIVCAAFDTVLGINV-AVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + + L + + Q+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP---------- 228
V+L G Y VD+WS+GCI E+ +F G IDQ K+ LGTP
Sbjct: 196 VIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 229 -------NERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
N +P I F+ FP W + SE + DLL K++ DP RI
Sbjct: 255 TVRNYVENRPKYPGI----KFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRI 310
Query: 282 SAKRAVQHPY 291
S A++HPY
Sbjct: 311 SVDEALRHPY 320
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 144 bits (364), Expect = 1e-34
Identities = 103/310 (33%), Positives = 149/310 (47%), Gaps = 34/310 (10%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y++L+ +G G G+V A D V A+KK+ +++ A RE+ LLK +
Sbjct: 23 LKRYQQLKPIGSGAQGIVCAAFDTVLGINV-AVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +YLV E +D +L + + L + + Q+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP---------- 228
V+L G Y VD+WS+GCI E+ +F G IDQ K+ LGTP
Sbjct: 196 VIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 229 -------NERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
N +P I F+ FP W + SE + DLL K++ DP RI
Sbjct: 255 TVRNYVENRPKYPGI----KFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRI 310
Query: 282 SAKRAVQHPY 291
S A++HPY
Sbjct: 311 SVDEALRHPY 320
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 144 bits (363), Expect = 2e-34
Identities = 108/312 (34%), Positives = 150/312 (47%), Gaps = 31/312 (9%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
T Y L + G G V A DL RV A+KK++ A RE LL +K
Sbjct: 36 TRYVNLSFLNAGAQGTVVMADDLVTTQRV-AIKKMQQPFVMTMSAKRAYREFILLTTIKH 94
Query: 65 DNIVRLYDIVHSDA-----HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
NI+RL + D ++YLV E + +L + + D + F+ Q
Sbjct: 95 PNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLDH----KTLSFFVYQSLC 150
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHE-IVTLWYRAPE 178
I + H +IHRDLKP N+++N LK+ DFGLAR V + +VT +YRAPE
Sbjct: 151 AIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPE 210
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI-I 237
V+LG YS VD+WS+GCIFAEM N LF G IDQ KI+ VLGTP++ +
Sbjct: 211 VILG-LPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQ 269
Query: 238 YLPDFKTTFPKWNRRNLSEVIPSLDANGI----------------DLLDKLITYDPIHRI 281
+ + P+ R SE++P D N + DLL ++ +P R
Sbjct: 270 SAAMYVRSLPRHQARAFSEIVP--DTNFLPETENPRVHLTPHVARDLLFNMLKINPEERY 327
Query: 282 SAKRAVQHPYFK 293
S + A+ HPY K
Sbjct: 328 SVEDALNHPYVK 339
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 144 bits (363), Expect = 2e-34
Identities = 102/309 (33%), Positives = 150/309 (48%), Gaps = 26/309 (8%)
Query: 1 MSELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLK 60
M L Y+ L +G G G+V A D +N VA+KK+ ++ A RE+ L+
Sbjct: 113 MVVLKRYQNLRLIGSGAQGIVCSAFDTV-RNEQVAIKKLSRPFQNVTHAKRAYRELKLMS 171
Query: 61 ELKDDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMM 115
+ NI+ + + + + LY+V E +D +L + ++ L + +
Sbjct: 172 LVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ-----MDLDHERLSYLLY 226
Query: 116 QLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYR 175
Q+ GI + H+ IIHRDLKP N+++ D LK+ DFGLAR + T +VT +YR
Sbjct: 227 QMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLART-AIEAFMMTPYVVTRYYR 285
Query: 176 APEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPN----ER 231
APEV+LG Y VDVWSIGCIF E+ + LF G IDQ +I LGTP+ ER
Sbjct: 286 APEVILG-MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLER 344
Query: 232 TWPDI---------IYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRIS 282
P + F+ F ++ A DLL +++ DP RIS
Sbjct: 345 LQPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRIS 404
Query: 283 AKRAVQHPY 291
A++HPY
Sbjct: 405 VDDALRHPY 413
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 144 bits (362), Expect = 2e-34
Identities = 102/308 (33%), Positives = 152/308 (49%), Gaps = 30/308 (9%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y+ L+ +G G G+V A D + R VA+KK+ +++ A RE+ L+K +
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILE-RNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +Y+V E +D +L + ++ L + + Q+
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
V+L G Y VD+WS+GCI EM K LF G IDQ K+ LGTP +
Sbjct: 196 VIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-- 252
Query: 239 LPDFKT---TFPKWNRRNLSEVIPSL------------DANGIDLLDKLITYDPIHRISA 283
P +T PK+ + ++ P + + DLL K++ D RIS
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 284 KRAVQHPY 291
A+QHPY
Sbjct: 313 DEALQHPY 320
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 144 bits (362), Expect = 2e-34
Identities = 103/311 (33%), Positives = 159/311 (51%), Gaps = 32/311 (10%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y + +G G++GVVY+A L +VA+KK+ + + RE+ ++++L
Sbjct: 55 SYTDTKVIGNGSFGVVYQA-KLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDHC 107
Query: 66 NIVRLYDIVHSDAHK-----LYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCK 119
NIVRL +S K L LV +++ + R + Q L +K +M QL +
Sbjct: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFR 167
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRA 176
+AY H+ I HRD+KPQNLL++ D LKL DFG A+ G P +Y I + +YRA
Sbjct: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY---ICSRYYRA 224
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP-------- 228
PE++ G Y++ +DVWS GC+ AE+ +P+F GDS +DQ+ +I +VLGTP
Sbjct: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM 284
Query: 229 ----NERTWPDIIYLPDFKTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISA 283
E +P I P K + + + V P I L +L+ Y P R++
Sbjct: 285 NPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTP 344
Query: 284 KRAVQHPYFKE 294
A H +F E
Sbjct: 345 LEACAHSFFDE 355
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 144 bits (362), Expect = 2e-34
Identities = 102/308 (33%), Positives = 152/308 (49%), Gaps = 30/308 (9%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y+ L+ +G G G+V A D + R VA+KK+ +++ A RE+ L+K +
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILE-RNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +Y+V E +D +L + ++ L + + Q+
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
V+L G Y VD+WS+GCI EM K LF G IDQ K+ LGTP +
Sbjct: 196 VIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-- 252
Query: 239 LPDFKT---TFPKWNRRNLSEVIPSL------------DANGIDLLDKLITYDPIHRISA 283
P +T PK+ + ++ P + + DLL K++ D RIS
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 284 KRAVQHPY 291
A+QHPY
Sbjct: 313 DEALQHPY 320
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 144 bits (362), Expect = 2e-34
Identities = 101/308 (32%), Positives = 151/308 (48%), Gaps = 30/308 (9%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y+ L+ +G G G+V A D + R VA+KK+ +++ A RE+ L+K +
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILE-RNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +Y+V E +D +L + ++ L + + Q+
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
V+L G Y VD+WS+GCI EM LF G IDQ K+ LGTP +
Sbjct: 196 VIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-- 252
Query: 239 LPDFKT---TFPKWNRRNLSEVIPSL------------DANGIDLLDKLITYDPIHRISA 283
P +T PK+ + ++ P + + DLL K++ D RIS
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 284 KRAVQHPY 291
A+QHPY
Sbjct: 313 DEALQHPY 320
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 144 bits (362), Expect = 2e-34
Identities = 101/308 (32%), Positives = 151/308 (48%), Gaps = 30/308 (9%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
L Y+ L+ +G G G+V A D + R VA+KK+ +++ A RE+ L+K +
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILE-RNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 64 DDNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLC 118
NI+ L ++ + +Y+V E +D +L + ++ L + + Q+
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-----MELDHERMSYLLYQML 136
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPE
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
V+L G Y VD+WS+GCI EM LF G IDQ K+ LGTP +
Sbjct: 196 VIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKL-- 252
Query: 239 LPDFKT---TFPKWNRRNLSEVIPSL------------DANGIDLLDKLITYDPIHRISA 283
P +T PK+ + ++ P + + DLL K++ D RIS
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 284 KRAVQHPY 291
A+QHPY
Sbjct: 313 DEALQHPY 320
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 142 bits (359), Expect = 4e-34
Identities = 99/300 (33%), Positives = 152/300 (50%), Gaps = 37/300 (12%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
VG G++G+V++A R VVA+KK+ + + RE+ +++ L N V L
Sbjct: 89 VGTGSFGMVFQA-KCRETGEVVAIKKVLQDKRYKN------RELQIMQMLDHPNAVALKH 141
Query: 73 IVHS--DAHKLYL--VFEFLDLDLKRYMESIPKDQPLGGNI-IKKFMMQLCKGIAYCH-A 126
S D ++YL V EF+ + R S + L I +K + Q+C+ +AY H +
Sbjct: 142 SFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRALAYIHNS 201
Query: 127 HRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRAPEVLLGG 183
+ HRD+KPQNLL+N LK+ DFG A+ G P +Y I + +YRAPE++ G
Sbjct: 202 FGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNVSY---ICSRYYRAPELIFGA 258
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFK 243
+Y+T +D+WS GC+ AE+ +PLF G+S +DQ+ +I +VLGTP + K
Sbjct: 259 SEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTRE---------EIK 309
Query: 244 TTFPKWNRRNLSEVIP---------SLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P + ++ P L +DLL + Y P R +A A HP F E
Sbjct: 310 CMNPNYTEFKFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTALEACIHPLFDE 369
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 141 bits (356), Expect = 1e-33
Identities = 95/305 (31%), Positives = 163/305 (53%), Gaps = 36/305 (11%)
Query: 4 LTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELK 63
+ Y+ +++G G Y V++ R + + A+K +R + RE+ +L+ L
Sbjct: 34 IEKYQIYQRMGRGKYSEVFEGRKDREKIVIKALKPVR--------KAKICREVLILRNLS 85
Query: 64 DDNIVRLYDIVHSDAHKLY-LVFEFLDLD--LKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
NI++L D+V ++Y L+FE+++ + K + + KD I ++ Q+
Sbjct: 86 HKNIIKLMDVVVDPESQIYSLIFEYIEHEDYAKIFEKLCYKD-------IVEYSRQILSA 138
Query: 121 IAYCHAHRIIHRDLKPQNLLINR-DGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 179
++YCH+ IIHRD+KPQN++IN+ LK+ D+GLA F P + Y+ + + +Y+ PE+
Sbjct: 139 LSYCHSMGIIHRDIKPQNMVINQARRELKIIDWGLAE-FYHPKKEYSVRVASRYYKGPEL 197
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMC-NRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
L+ Y +D+WS GC+ AE+ ++P F G+S DQ+ KI R+LG + + Y
Sbjct: 198 LVDYPYYDYSLDIWSFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKK-----Y 252
Query: 239 LPDFKTT--FPKW----NRRNLSEVIP----SLDANGIDLLDKLITYDPIHRISAKRAVQ 288
+ +K PK+ R LS P L N IDLL+K++ YD R +A ++
Sbjct: 253 VRKYKMAPLNPKYEGVGERVLLSSFTPPGKTGLYTNAIDLLEKILIYDHQDRPTADECLR 312
Query: 289 HPYFK 293
HP F+
Sbjct: 313 HPLFE 317
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 140 bits (353), Expect = 2e-33
Identities = 75/203 (36%), Positives = 114/203 (55%), Gaps = 14/203 (6%)
Query: 99 IPKDQPLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAF 158
I QPL ++ F+ QL +G+ Y H+ ++IHRDLKP NLL+N + LK+GDFG+AR
Sbjct: 9 IHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGL 68
Query: 159 GVPLRAY----THEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSE 214
+ T + T WYRAPE++L +Y+ +D+WS+GCIF EM R+ LF G +
Sbjct: 69 CTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNY 128
Query: 215 IDQIFKIFRVLGTPNERTWPDIIY------LPDFKTTFPKWNRRNLSEVIPSLDANGIDL 268
+ Q+ I VLGTP+ P +I + + + P V P D + L
Sbjct: 129 VHQLQLIMMVLGTPS----PAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSL 184
Query: 269 LDKLITYDPIHRISAKRAVQHPY 291
L +++ ++P RISA A++HP+
Sbjct: 185 LGRMLRFEPSARISAAAALRHPF 207
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 139 bits (351), Expect = 4e-33
Identities = 104/308 (33%), Positives = 149/308 (47%), Gaps = 31/308 (10%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
+ Y L +G G G+V A D Q V A+KK+ ++ A RE L+K +
Sbjct: 22 SRYINLRPIGSGAQGIVCAAYDTITQQNV-AIKKLSRPFQNVTHAKRAYREFKLMKLVNH 80
Query: 65 DNIVRLYDIVH-----SDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
NI+ L + + +YLV E +D +L + ++ L + + + Q+
Sbjct: 81 KNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ-----MDLDHDRMSYLLYQMLC 135
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 179
GI + H+ IIHRDLKP N+++ D LK+ DFGLAR G T +VT +YRAPEV
Sbjct: 136 GIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTF-MMTPYVVTRYYRAPEV 194
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPN----ERTWPD 235
+L G Y+ VD+WS+GCI EM LF G IDQ KI LGTP+ +R P
Sbjct: 195 IL-GMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPT 253
Query: 236 IIYLPD---------FKTTFPKW---NRRNLSEVIPSLDANGIDLLDKLITYDPIHRISA 283
+ + F FP N N + + DA +LL K++ DP RIS
Sbjct: 254 VRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDAR--NLLSKMLVIDPEQRISV 311
Query: 284 KRAVQHPY 291
A++H Y
Sbjct: 312 DEALKHEY 319
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 139 bits (350), Expect = 5e-33
Identities = 94/300 (31%), Positives = 163/300 (54%), Gaps = 26/300 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y+ + K+G G Y V++A+++ + +VV KI + + + REI +L+ L+
Sbjct: 38 DYQLVRKLGRGKYSEVFEAINITNNEKVVV--KILKPVKKKKIK----REIKILENLRGG 91
Query: 66 -NIVRLYDIVHSDAHKL-YLVFEFLD-LDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
NI+ L DIV + LVFE ++ D K+ +++ I+ +M ++ K +
Sbjct: 92 PNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYD------IRFYMYEILKALD 145
Query: 123 YCHAHRIIHRDLKPQNLLINRDGN-LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
YCH+ I+HRD+KP N++I+ + L+L D+GLA F P + Y + + +++ PE+L+
Sbjct: 146 YCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLV 204
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNERTWPD---II 237
+ Y +D+WS+GC+ A M RK P F G DQ+ +I +VLGT + + D I
Sbjct: 205 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264
Query: 238 YLPDFKTTFPKWNRRNLSEVIPS-----LDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
P F + +R+ + S + +D LDKL+ YD R++A+ A++HPYF
Sbjct: 265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 139 bits (350), Expect = 5e-33
Identities = 93/302 (30%), Positives = 160/302 (52%), Gaps = 27/302 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y+ +G G++GVV++A L + +V A+KK+ + + RE+ +++ L
Sbjct: 101 SYRAEHVIGTGSFGVVFQAKCLETEEKV-AIKKVLQDKRYKN------RELQIMRMLDHP 153
Query: 66 NIVRL----YDIVHSDAHKLYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
N+V L + D L LV E++ + R S K +Q + I+ + Q+C+
Sbjct: 154 NVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTYQICRA 213
Query: 121 IAYCH-AHRIIHRDLKPQNLLINR-DGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+ Y H + HRD+KPQNLL+N +K+ DFG A+ +P I + +YRAPE
Sbjct: 214 MNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKML-IPGEPNISYICSRYYRAPE 272
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI-I 237
++ G +Y++ +D+WS+GC+ AE+ PLF G++ +DQ+ +I ++LGTP ++
Sbjct: 273 LIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEIKNMNP 332
Query: 238 YLPDFKTTFPK-----WNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
DFK FP+ W++ +V P +DL +L+ Y P R +A A HP+F
Sbjct: 333 RYNDFK--FPQIKAQPWHKIFRRQVSP----EAMDLASRLLQYSPNLRCTALEACAHPFF 386
Query: 293 KE 294
+
Sbjct: 387 DD 388
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 137 bits (344), Expect = 2e-32
Identities = 96/298 (32%), Positives = 155/298 (51%), Gaps = 19/298 (6%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y VG G++G+V++A L VA+KK+ + + RE+ L++ +
Sbjct: 39 SYMAERVVGTGSFGIVFQAKCLE-TGETVAIKKVLQDRRYKN------RELQLMRVMDHP 91
Query: 66 NIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
N+V L S K L LV E++ L R ++ +Q + +K +M Q+ +G
Sbjct: 92 NVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRG 151
Query: 121 IAYCH-AHRIIHRDLKPQNLLINR-DGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+AY H + HRDLKPQNLL++ +K+ DFG A+ V A I + +YRAPE
Sbjct: 152 LAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQL-VKGEANISYICSRFYRAPE 210
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP-NERTWPDII 237
++ G +Y+T +D+WS GC+ AE+ +PLF G++ +DQ+ +I +VLGTP E
Sbjct: 211 LIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNP 270
Query: 238 YLPDFKTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ DF+ FP+ ++ + ID +L+ Y P R +A A HP+F E
Sbjct: 271 HYTDFR--FPQIKAHPWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDE 326
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 135 bits (340), Expect = 7e-32
Identities = 90/300 (30%), Positives = 160/300 (53%), Gaps = 26/300 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y+ + K+G G Y V++A+++ + V KI + + + REI +L+ L+
Sbjct: 36 DYQLVRKLGRGKYSEVFEAINITTTEKCVV--KILKPVKKKKIK----REIKILENLRGG 89
Query: 66 -NIVRLYDIVHSDAHKL-YLVFEFLD-LDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
NI+ L +V + L+FE ++ D K+ +++ + I+ ++ +L K +
Sbjct: 90 TNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYE------IRYYLFELLKALD 143
Query: 123 YCHAHRIIHRDLKPQNLLINRDGN-LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
YCH+ I+HRD+KP N++I+ + L+L D+GLA F P + Y + + +++ PE+L+
Sbjct: 144 YCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLV 202
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNERTWPD---II 237
+ Y +D+WS+GC+ A M RK P F G DQ+ +I +VLGT + D I
Sbjct: 203 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNID 262
Query: 238 YLPDFKTTFPKWNRRNLSEVIPS-----LDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
P F + +R+ + S + +D LDKL+ YD + R++A+ A+ HPYF
Sbjct: 263 LDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF 322
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 135 bits (339), Expect = 9e-32
Identities = 96/294 (32%), Positives = 159/294 (53%), Gaps = 27/294 (9%)
Query: 13 VGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYD 72
VG+G++G+V++A L VA+KK+ + + RE+ ++ L N+V L
Sbjct: 80 VGQGSFGIVFQAKCLE-TGETVAIKKVLQDKRYKN------RELQTMRLLDHPNVVSLKH 132
Query: 73 IVHSDAHK----LYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKGIAYCHAH 127
S K L LV E++ + R + + +Q + +K + Q+C+ +AY H
Sbjct: 133 CFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYIHGG 192
Query: 128 -RIIHRDLKPQNLLIN-RDGNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRAPEVLLGG 183
+ HRD+KPQNLL+N +KL DFG A+ G P +Y I + +YRAPE++ G
Sbjct: 193 VGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISY---ICSRYYRAPELIFGA 249
Query: 184 KQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL-PDF 242
+Y+T +D+WS GC+ AE+ +PLF G+S +DQ+ +I +VLGTP T +I + P++
Sbjct: 250 TEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTP---TREEIKCMNPNY 306
Query: 243 -KTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ FP+ ++ +DL+ +L+ Y P R +A A+ HP+F E
Sbjct: 307 TEFKFPQIKAHPWHKIFHKRTPPEAVDLVSRLLQYSPNLRSTA--AIVHPFFDE 358
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 135 bits (339), Expect = 9e-32
Identities = 97/301 (32%), Positives = 161/301 (53%), Gaps = 25/301 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y VG G++GVV++A L VA+KK+ + + RE+ ++ L
Sbjct: 72 SYMAERVVGHGSFGVVFQAKCLE-TGETVAIKKVLQDRRYKN------RELQTMRLLDHP 124
Query: 66 NIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
N+V L S K L LV E++ + R ++ K +Q + +K + Q+ +
Sbjct: 125 NVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRS 184
Query: 121 IAYCH-AHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRA 176
++Y H + HRD+KPQNLL+N +KL DFG A+ G P +Y I + +YRA
Sbjct: 185 LSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISY---ICSRYYRA 241
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE++ G +Y+T +DVWS GC+ AE+ +PLF G+S +DQ+ +I +VLGTP T +I
Sbjct: 242 PELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTP---TREEI 298
Query: 237 IYL-PDF-KTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ P++ + FP+ ++ + +DL+ +L+ Y P R +A ++ HP+F
Sbjct: 299 KCMNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFD 358
Query: 294 E 294
E
Sbjct: 359 E 359
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 134 bits (338), Expect = 1e-31
Identities = 96/311 (30%), Positives = 160/311 (50%), Gaps = 38/311 (12%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRV-------VAMKKIRLESEDEGVPSTAIRE 55
E +Y+ + KVG G Y V++ +++ + + V KKIR RE
Sbjct: 30 EQDDYEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKKKKIR-------------RE 76
Query: 56 ISLLKEL-KDDNIVRLYDIVHSDAHKL-YLVFEFLDLDLKRYMESIPKDQPLGGNIIKKF 113
I +L+ L NIV+L D+V K L+FE+++ + + D I+ +
Sbjct: 77 IKILQNLCGGPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPTLTDYD-----IRYY 131
Query: 114 MMQLCKGIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAFGVPLRAYTHEIVTL 172
+ +L K + +CH+ I+HRD+KP N++I+ + L+L D+GLA F P + Y + +
Sbjct: 132 IYELLKALDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAE-FYHPGKEYNVRVASR 190
Query: 173 WYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNER 231
+++ PE+L+ + Y +D+WS+GC+FA M RK P F G DQ+ KI +VLGT
Sbjct: 191 YFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELN 250
Query: 232 TWPDIIYL---PDFKTTFPKWNRRNLSEVIPS-----LDANGIDLLDKLITYDPIHRISA 283
+ + L + + +R+ S+ I + + ID LDKL+ YD R++A
Sbjct: 251 AYLNKYQLELDTQLEALVGRHSRKPWSKFINADNRHLVSPEAIDYLDKLLRYDHQDRLTA 310
Query: 284 KRAVQHPYFKE 294
K A+ HPYF +
Sbjct: 311 KEAMAHPYFAQ 321
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 134 bits (337), Expect = 2e-31
Identities = 98/297 (32%), Positives = 151/297 (49%), Gaps = 18/297 (6%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y E VG G++GVV V + N+ VA+KK+ + + RE+ +K L
Sbjct: 163 SYPTTEVVGHGSFGVVVTTVIIE-TNQKVAIKKVLQDRRYKN------RELETMKMLCHP 215
Query: 66 NIVRL----YDIVHSDAHKLYLVFEFLDLDL-KRYMESIPKDQPLGGNIIKKFMMQLCKG 120
N V L Y+ D L LV +++ L +R + + IK + QL K
Sbjct: 216 NTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKA 275
Query: 121 IAYCH-AHRIIHRDLKPQNLLINRDG-NLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+ Y H RI HRD+KPQNLL++ + K+ DFG A+ P + I + +YRAPE
Sbjct: 276 LNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLK-PDQPNVSYICSRYYRAPE 334
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
++ G YS VDVWS C+ AE+ KPLFSG+S IDQ+ +I +++G P + +
Sbjct: 335 LMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGM-- 392
Query: 239 LPDFKT-TFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
P+++ FP L+E+ + D + +DLL K + Y P R+ + + YF E
Sbjct: 393 NPNYEDHVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDE 449
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 134 bits (337), Expect = 2e-31
Identities = 96/311 (30%), Positives = 160/311 (50%), Gaps = 38/311 (12%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRV-------VAMKKIRLESEDEGVPSTAIRE 55
E +Y+ + KVG G Y V++ +++ + + V KKIR RE
Sbjct: 30 EQDDYEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKKKKIR-------------RE 76
Query: 56 ISLLKEL-KDDNIVRLYDIVHSDAHKL-YLVFEFLDLDLKRYMESIPKDQPLGGNIIKKF 113
I +L+ L NIV+L D+V K L+FE+++ + + D I+ +
Sbjct: 77 IKILQNLCGGPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPTLTDYD-----IRYY 131
Query: 114 MMQLCKGIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAFGVPLRAYTHEIVTL 172
+ +L K + +CH+ I+HRD+KP N++I+ + L+L D+GLA F P + Y + +
Sbjct: 132 IYELLKALDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAE-FYHPGKEYNVRVASR 190
Query: 173 WYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNER 231
+++ PE+L+ + Y +D+WS+GC+FA M RK P F G DQ+ KI +VLGT
Sbjct: 191 YFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELN 250
Query: 232 TWPDIIYL---PDFKTTFPKWNRRNLSEVIPS-----LDANGIDLLDKLITYDPIHRISA 283
+ + L P + + +R+ S+ I + + ID LDKL+ YD R++A
Sbjct: 251 AYLNKYQLELDPQLEALVGRHSRKPWSKFINADNQHLVSPEAIDFLDKLLRYDHQDRLTA 310
Query: 284 KRAVQHPYFKE 294
K A+ H YF +
Sbjct: 311 KEAMAHAYFAQ 321
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 134 bits (337), Expect = 2e-31
Identities = 97/301 (32%), Positives = 160/301 (52%), Gaps = 25/301 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y VG G++GVV++A L VA+KK+ + + RE+ ++ L
Sbjct: 68 SYMAERVVGHGSFGVVFQAKCLE-TGETVAIKKVLQDRRYKN------RELQTMRLLDHP 120
Query: 66 NIVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
N+V L S K L LV E++ + R ++ K +Q + +K + Q+ +
Sbjct: 121 NVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRA 180
Query: 121 IAYCH-AHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRA 176
++Y H + HRD+KPQNLL+N +KL DFG A+ G P +Y I + +YRA
Sbjct: 181 LSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISY---ICSRYYRA 237
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE++ G +Y+T +DVWS GC+ AE+ +PLF G+S +DQ+ +I +VLGTP T +I
Sbjct: 238 PELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTP---TREEI 294
Query: 237 IYL-PDF-KTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ P++ + FP+ ++ + +DL+ +L+ Y P R +A + HP+F
Sbjct: 295 KCMNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFD 354
Query: 294 E 294
E
Sbjct: 355 E 355
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 134 bits (336), Expect = 2e-31
Identities = 97/301 (32%), Positives = 157/301 (51%), Gaps = 25/301 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y VG G++G+V++A L VA+KK+ + + RE+ L++ +
Sbjct: 71 SYMAERVVGTGSFGIVFQAKCLE-TGESVAIKKVLQDRRYKN------RELQLMRLMDHP 123
Query: 66 NIVRL----YDIVHSDAHKLYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
N+V L + D L LV E++ L R ++ +Q + +K + Q+ +G
Sbjct: 124 NVVSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRG 183
Query: 121 IAYCH-AHRIIHRDLKPQNLLINR-DGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+AY H A + HRD+KPQNLL++ KL DFG A+ V A I + +YRAPE
Sbjct: 184 LAYIHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVL-VKGEANISYICSRYYRAPE 242
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
++ G +Y++ +D+WS GC+ AE+ +PLF G++ +DQ+ +I +VLGTP T +I
Sbjct: 243 LIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTP---TREEIRC 299
Query: 239 L----PDFKTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFK 293
+ DF+ FP+ +V + IDL +L+ Y P R +A A HP+F
Sbjct: 300 MNPNYTDFR--FPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFN 357
Query: 294 E 294
E
Sbjct: 358 E 358
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 134 bits (336), Expect = 2e-31
Identities = 99/302 (32%), Positives = 161/302 (52%), Gaps = 26/302 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL-KD 64
+Y+ + KVG G Y V++ ++ R V KI + + + REI +L+ L
Sbjct: 33 DYEVVRKVGRGKYSEVFEGKNVNTNERCVI--KILKPVKKKKIK----REIKILQNLCGG 86
Query: 65 DNIVRLYDIVHSDAHKL-YLVFEFLD-LDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
NIV+LYDIV + K LVFEF++ +D K ++ I+ ++ +L K +
Sbjct: 87 PNIVKLYDIVRDEHSKTPSLVFEFVNSVDFKVLYPTLTDYD------IRYYIYELLKALD 140
Query: 123 YCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 181
+CH+ I+HRD+KP N++I+ L+L D+GLA F P + Y + + +++ PE+L+
Sbjct: 141 FCHSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLAE-FYHPGKEYNVRVASRYFKGPELLV 199
Query: 182 GGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL- 239
+ Y +D+WS+GC+FA M RK P F G DQ+ KI +VLGT + + L
Sbjct: 200 DLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTNELDHYLNKYQLD 259
Query: 240 --PDFKTT----FPK-WNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYF 292
P + PK W++ ++ + ID LDKL+ YD R++A+ A+ HPYF
Sbjct: 260 LDPQLEALVGRHVPKPWSKFINADNQHLVSPEAIDFLDKLLQYDHQDRLTAREAMDHPYF 319
Query: 293 KE 294
+
Sbjct: 320 AQ 321
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 133 bits (335), Expect = 3e-31
Identities = 93/299 (31%), Positives = 159/299 (53%), Gaps = 21/299 (7%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y VG G++GVV++A L +V A+KK+ + + RE+ +++
Sbjct: 137 SYMAQRVVGTGSFGVVFQAKCLETGEQV-AIKKVLQDKRYKN------RELQIMRLQDHP 189
Query: 66 NIVRL----YDIVHSDAHKLYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
N+VRL + D L LV E++ + R + K +Q + ++ + Q+C+
Sbjct: 190 NVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTYQICRA 249
Query: 121 IAYCH-AHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+ Y H + HRD+KPQNLL+N + LK+ DFG A+ VP I + +YRAPE
Sbjct: 250 LNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKML-VPGEPNISYICSRYYRAPE 308
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIY 238
++ G +Y+ +D+WS GC+ AE+ +PLF G+S IDQ+ +I ++LGTP T +I
Sbjct: 309 LIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTP---TREEIRC 365
Query: 239 L-PDF-KTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
+ P++ + FP+ ++ + +DL+ +L+ Y P R +A A HP+F +
Sbjct: 366 MNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFFDD 424
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 133 bits (335), Expect = 3e-31
Identities = 96/303 (31%), Positives = 157/303 (51%), Gaps = 29/303 (9%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD 65
+Y VG G++G+V++A L VA+KK+ + + RE+ L++ +
Sbjct: 69 SYMAERVVGTGSFGIVFQAKCLE-TGESVAIKKVLQDRRYKN------RELQLMRPMDHP 121
Query: 66 NIVRL----YDIVHSDAHKLYLVFEFLDLDLKRYMESIPK-DQPLGGNIIKKFMMQLCKG 120
N++ L + D L LV E++ L R + +Q + +K + Q+ +G
Sbjct: 122 NVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRG 181
Query: 121 IAYCHA-HRIIHRDLKPQNLLINR-DGNLKLGDFGLARAF--GVPLRAYTHEIVTLWYRA 176
+AY H + HRD+KPQNLL++ +KL DFG A+ G P +Y I + +YRA
Sbjct: 182 LAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNISY---ICSRYYRA 238
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDI 236
PE++ G +Y+ +D+WS GC+ AE+ +PLF G++ +DQ+ +I +VLGTP T +I
Sbjct: 239 PELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTP---TREEI 295
Query: 237 IYL----PDFKTTFPKWNRRNLSEVI-PSLDANGIDLLDKLITYDPIHRISAKRAVQHPY 291
+ DF+ FP+ +V + IDL +L+ Y P R +A A HP+
Sbjct: 296 RCMNPNYTDFR--FPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPF 353
Query: 292 FKE 294
F E
Sbjct: 354 FNE 356
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 132 bits (332), Expect = 6e-31
Identities = 92/299 (30%), Positives = 158/299 (52%), Gaps = 34/299 (11%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ +E +G G++GVV K +D RH A+K++ + RE+ +L E+ N
Sbjct: 56 YRYVEMIGRGSFGVVVKIMDDRHN--FFALKRVYQDRRYHN------RELGILMEVDHPN 107
Query: 67 IVRLYDIVHSDAHK----LYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIA 122
IVRL H+D L ++ +F+ ++L+ Y+++ ++ + I+ Q+ +G+
Sbjct: 108 IVRLVSYFHTDKTSSGAYLNIITDFVGMNLEEYIKA---NRGVETEEIRSVYRQILEGLR 164
Query: 123 YCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
Y H I HRD+KP N+LI+ +G +K+ D G A+ R T+ I + +YRAPE LL
Sbjct: 165 YLHEKNICHRDMKPSNILIDTNGLVKICDLGSAKVIKSGERNITY-ICSRFYRAPENLLD 223
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRKPLFSGD---SEIDQIFKIFRVLGTPNERTWPDIIYL 239
K+Y +D+WS+GC+ AE + P+F GD S +++I +I RV T D+I L
Sbjct: 224 YKEYDFKIDIWSVGCVIAEFRHPGPIFKGDTSGSTLNRILEIVRV-------TSDDLIGL 276
Query: 240 ----PDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
PD K R E S D + +++L+K + + P R +A ++ +F++
Sbjct: 277 GCLKPDLKQGV---GIRKYLEAFFS-DPDLLEVLEKSLAFSPCKRSTASELLRKQFFQQ 331
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 129 bits (325), Expect = 4e-30
Identities = 104/313 (33%), Positives = 153/313 (48%), Gaps = 31/313 (9%)
Query: 5 TNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
T Y L+ + G G+V A DL RV A+KK++ A RE LL LK
Sbjct: 27 TRYVNLKFLNVGAQGIVVMADDLVTTQRV-AIKKMQQPFLLTMSARRAYREFILLTTLKH 85
Query: 65 DNIVRLYDIVHSDA-----HKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
NI+RL + D ++YLV EF+ +L + + D ++ + LC
Sbjct: 86 PNIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLRLDHETLSFLVYQ---SLC- 141
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 179
I + H IHRDLKP N+++N LK+ DFGLAR V +R + + T +YRAPEV
Sbjct: 142 AIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARRRNVDMRMSDY-VGTRYYRAPEV 200
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYL 239
+LG YS VD+WS+GCI AEM N LF G DQ +I VL TP++ + +
Sbjct: 201 ILG-LNYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHFINQLEPI 259
Query: 240 -PDFKTTFPKWNRRNLSEVIPSLDANGI----------------DLLDKLITYDPIHRIS 282
+ + P+ R +E++P D+N + DLL ++ +P R S
Sbjct: 260 GAVYVRSLPQHLARAFNEIVP--DSNFLPETENPKDHLTLHMARDLLFNMLKINPEERYS 317
Query: 283 AKRAVQHPYFKEE 295
+ A+ HPY ++
Sbjct: 318 VEDALNHPYTMDD 330
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 129 bits (323), Expect = 7e-30
Identities = 92/310 (29%), Positives = 160/310 (50%), Gaps = 39/310 (12%)
Query: 8 KRLEKVGEGTYGVVYKAV---DLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKD 64
K K+G G +G V +A D ++ A+KK+ +E + RE+ +L+
Sbjct: 36 KEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKS------RELQILRIADH 89
Query: 65 DNIVRL-YDIVHSDA--HKLY------LVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMM 115
NIV+L Y H +K+Y + E L +++ RY+ + + PL I+ +
Sbjct: 90 PNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTN-KLEMPL--KHIRLYTY 146
Query: 116 QLCKGIAYCHAHRIIHRDLKPQNLLINRD-GNLKLGDFGLARAF--GVPLRAYTHEIVTL 172
Q+ +G+ Y H + HRD+KP N+L++ + G LK+ DFG A+ P +Y I +
Sbjct: 147 QIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISY---ICSR 203
Query: 173 WYRAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERT 232
+YRAPE+++G QY+T +D+W +GC+ EM K +F G + Q+ +I ++LG P++R
Sbjct: 204 FYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKR- 262
Query: 233 WPDIIYLPD--------FKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAK 284
I+ + K F +++ + +GIDLL K++ Y+P R+S +
Sbjct: 263 ---FIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPR 319
Query: 285 RAVQHPYFKE 294
R + H +F E
Sbjct: 320 RILAHQFFNE 329
>At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 432
Score = 129 bits (323), Expect = 7e-30
Identities = 94/299 (31%), Positives = 158/299 (52%), Gaps = 24/299 (8%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL-KD 64
+Y+ + KVG G Y V++ + + V KI + + + REI +L+ L
Sbjct: 131 DYEVVRKVGRGKYSEVFEGIHATDNEKCVI--KILKPVKKKKIK----REIKILQNLCGG 184
Query: 65 DNIVRLYDIVHSDAHKL-YLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAY 123
NIV+L DIV K L+FE ++ K + P L ++ ++ +L K + +
Sbjct: 185 PNIVKLLDIVRDQQSKTPSLIFEHVNN--KDFKVLYPT---LSDYDVRYYIFELLKALDF 239
Query: 124 CHAHRIIHRDLKPQNLLINRDGN-LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLG 182
CH+ I+HRD+KP N++I+ + L+L D+GLA F P + Y + + +++ PE+L+
Sbjct: 240 CHSRGIMHRDVKPHNVMIDHEQRKLRLIDWGLAE-FYHPGKEYNVRVASRYFKGPELLVD 298
Query: 183 GKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNERTWPD---IIY 238
+ Y +D+WS+GC+FA M RK P F G DQ+ KI +VLGT + + I
Sbjct: 299 LQDYDYSLDLWSLGCMFAGMIFRKEPFFYGHDNYDQLVKIAKVLGTDELNAYLNKYRIEL 358
Query: 239 LPDFKTTFPKWNRRNLSEVIPSLDAN-----GIDLLDKLITYDPIHRISAKRAVQHPYF 292
P+ + + +R+ ++ I S + + +D +DKL+ YD R +AK A+ HPYF
Sbjct: 359 DPNLTSLVGRHSRKPWTKFINSENQHLAVPEAVDFVDKLLRYDHQERPTAKEAMAHPYF 417
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 127 bits (319), Expect = 2e-29
Identities = 96/312 (30%), Positives = 165/312 (52%), Gaps = 39/312 (12%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDD- 65
Y+ LE +G+G++G V +A+D + N VA+K IR + + A+ E+++L EL++
Sbjct: 198 YEILEVIGKGSFGQVIRALDHK-TNTHVAIKIIRNKKR---FLNQAVVELNILDELREKD 253
Query: 66 -----NIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMESIPKDQPLGGN--IIKKFMMQLC 118
N++ + D + H L + FE + L+L E I K+ G + +I++F +
Sbjct: 254 ADGSHNVIHMLDYTYFRKH-LCITFELMSLNL---YELIKKNNYNGFSMSLIRRFCNSIV 309
Query: 119 KGIAYCHAHRIIHRDLKPQNLLINRDGN--LKLGDFGLARAFGVPLRAYTHEIVTLWYRA 176
K + + IIH DLKP+N+L+ + G+ +K+ DFG + V + YT+ I + +YR+
Sbjct: 310 KCLRLLYKENIIHCDLKPENILLKQRGSSSIKVIDFG--SSCYVDRKIYTY-IQSRFYRS 366
Query: 177 PEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP-------- 228
PEV+LG QY T +D+WS+GCI AE+ PLF G++E++Q+ I VLG P
Sbjct: 367 PEVILG-LQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVLISVA 425
Query: 229 -------NERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRI 281
+ R P I + P ++L+ ++ D ID L + + +DP R+
Sbjct: 426 RRRRLFFDSRDAPRCITNTKGRKRSP--GSKSLAHILHCQDRYFIDFLQRCLEWDPAERM 483
Query: 282 SAKRAVQHPYFK 293
+ A H + +
Sbjct: 484 TPDEAAHHEFLQ 495
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 127 bits (318), Expect = 2e-29
Identities = 89/304 (29%), Positives = 158/304 (51%), Gaps = 26/304 (8%)
Query: 3 ELTNYKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKEL 62
++ +Y+ + K+G G Y V++ + +VV KI + + + REI +L+ L
Sbjct: 34 QIDDYQLVRKLGRGKYSEVFEGFKMSTDEKVVV--KILKPVKKKKIK----REIKILENL 87
Query: 63 KDD-NIVRLYDIVHSDAHKL-YLVFEFLD-LDLKRYMESIPKDQPLGGNIIKKFMMQLCK 119
+ NI+ L D+V + L+FE ++ D K+ Q L I+ ++ +L K
Sbjct: 88 RGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLY------QTLSDYDIRYYLYELLK 141
Query: 120 GIAYCHAHRIIHRDLKPQNLLINRDGN-LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPE 178
+ +CH+ I+HRD+KP N++I+ + L+L D+GLA F P + Y + + +++ PE
Sbjct: 142 ALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAE-FYHPRQDYNVRVASRYFKGPE 200
Query: 179 VLLGGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPNERTWPDII 237
+L+ + Y +D+WS+GC+ A M RK P F G DQ+ +I +VLGT +
Sbjct: 201 LLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARY 260
Query: 238 YL---PDFKTTFPKWNRRNLSEVIPS-----LDANGIDLLDKLITYDPIHRISAKRAVQH 289
++ P F + +R+ I + + +D LDKL+ YD R++A+ A+ H
Sbjct: 261 HIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGH 320
Query: 290 PYFK 293
YF+
Sbjct: 321 EYFR 324
>YIL035c [TDK] KOG0668 Casein kinase II alpha subunit
Length = 372
Score = 125 bits (314), Expect = 7e-29
Identities = 103/337 (30%), Positives = 169/337 (49%), Gaps = 62/337 (18%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVVAM-------KKIRLESE------DEGVPSTA 52
+Y+ KVG G Y V++ V L + ++V KKI+ E + +E VP T
Sbjct: 39 DYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTT 98
Query: 53 I----------REISLLKELKD----------DNIVRLYDIVHSDAHKL-YLVFEFLDLD 91
+ ++ +LK ++ NI+ L+DI+ K LVFE++D
Sbjct: 99 LPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNV 158
Query: 92 LKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLI-NRDGNLKLG 150
R + PK L I+ +M +L K + YCH+ I+HRD+KP N++I +++ L+L
Sbjct: 159 DFRIL--YPKLTDLE---IRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLI 213
Query: 151 DFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDVWSIGCIFAEMC-NRKPLF 209
D+GLA + V + Y + + +++ PE+L+ + Y +D+WS G + A M R+P F
Sbjct: 214 DWGLAEFYHVNME-YNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFF 272
Query: 210 SGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTTFPK------------WNRRNLSEV 257
G S DQ+ KI +VLGT + YL ++ T P+ W+ R +++
Sbjct: 273 HGTSNTDQLVKIVKVLGTSDFEK-----YLLKYEITLPREFYDMDQYIRKPWH-RFINDG 326
Query: 258 IPSLDANG--IDLLDKLITYDPIHRISAKRAVQHPYF 292
L N IDL+D L+ YD R++AK A+ HP+F
Sbjct: 327 NKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWF 363
>CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 381
Score = 124 bits (312), Expect = 1e-28
Identities = 92/297 (30%), Positives = 146/297 (48%), Gaps = 33/297 (11%)
Query: 24 AVDLRHQNRVVAMKKIRLESEDEGVP-STAIREISLLKELKDDNIVRLYDIVH-----SD 77
A D + RVV K + E+ D A RE+ ++++N V++Y I +
Sbjct: 34 AFDQISERRVVIKKVVLPENFDNWQHWRRAQRELFCTLHIQEENFVKMYSIYTWVETVEE 93
Query: 78 AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQ 137
+ Y V E++D +L+ ++ S P + L +IK +C + Y H+ R+ HRDLKP+
Sbjct: 94 MREFYTVREYMDWNLRNFILSTP--EKLDHKVIKSIFFDVCLAVQYMHSIRVGHRDLKPE 151
Query: 138 NLLINRDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYST-GVDVWSIG 196
N+LIN + K+ G A A T IV +YRAPE+L + VD+WS+G
Sbjct: 152 NVLINYEAIAKIS--GFAHANREDPFVNTPYIVQRFYRAPEILCETMDNNKPSVDIWSLG 209
Query: 197 CIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERTWPDIIYLPDFKTTF-------PKW 249
CI AE+ K LF+G ++IDQ F+I R LG P+ + + +PD TF
Sbjct: 210 CILAELLTGKILFTGQTQIDQFFQIVRFLGNPDLSFY---MQMPDSARTFFLGLPMNQYQ 266
Query: 250 NRRNLSEVIPS-----------LDAN-GIDLLDKLITYDPIHRISAKRAVQHPYFKE 294
N+ E P+ +D + DLL +++ +P RI ++ + HPY +E
Sbjct: 267 KPTNIHEHFPNSLFLDTMISEPIDCDLARDLLFRMLVINPDDRIDIQKILVHPYLEE 323
>SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 332
Score = 124 bits (310), Expect = 2e-28
Identities = 88/307 (28%), Positives = 158/307 (50%), Gaps = 38/307 (12%)
Query: 6 NYKRLEKVGEGTYGVVYKAVDLRHQNRVV--AMKKIRLESEDEGVPSTAIREISLLKELK 63
NY+ + KVG G Y V++ +++ + ++ + +K ++ + REI +L+ L
Sbjct: 42 NYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKIK--------REIKILQNLA 93
Query: 64 DD-NIVRLYDIVHSDAHKL-YLVFEFLD-LDLKRYMESIPKDQPLGGNIIKKFMMQLCKG 120
NI+ L DIV K L+FEF+D +D + + L I+ + +L K
Sbjct: 94 GGPNIISLLDIVRDPESKTPSLIFEFVDNIDFRTLYPT------LSDYDIRYYSYELLKA 147
Query: 121 IAYCHAHRIIHRDLKPQNLLIN-RDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEV 179
+ +CH+ I+HRD+KP N++I+ + L+L D+GLA + + Y + + +++ PE+
Sbjct: 148 LDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGME-YNVRVASRYFKGPEL 206
Query: 180 LLGGKQYSTGVDVWSIGCIFAEMCNRK-PLFSGDSEIDQIFKIFRVLGTPN--------- 229
L+ ++Y +D+WS G +FA + +K F G DQ+ KI +VLGT
Sbjct: 207 LVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTDELFAYVQKYQ 266
Query: 230 ---ERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIHRISAKRA 286
+R + +I+ + + NR N S + IDLL++L+ YD R++ + A
Sbjct: 267 IVLDRQYDNILGQYPKRDWYSFVNRDNRS----LANDEAIDLLNRLLRYDHQERLTCQEA 322
Query: 287 VQHPYFK 293
+ HPYF+
Sbjct: 323 MAHPYFQ 329
>Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 520
Score = 123 bits (309), Expect = 3e-28
Identities = 87/315 (27%), Positives = 166/315 (52%), Gaps = 43/315 (13%)
Query: 7 YKRLEKVGEGTYGVVYKAVDLRHQNRVVAMKKIRLESEDEGVPSTAIREISLLKELKDDN 66
Y+ LE +G+G++G V K +D ++ N +VA+K IR + A+ E+ +L+ L+ +
Sbjct: 104 YEVLETIGKGSFGQVAKCLDHKN-NELVALKIIRNKKRFH---QQALMELKILEALRKKD 159
Query: 67 IVRLYDIVHSD-----AHKLYLVFEFLDLDLKRYMESIPKDQPLGGNIIKKFMMQLCKGI 121
Y++VH + + FE L ++L M++ Q +I+++F + + K +
Sbjct: 160 KDNTYNVVHMKDFFYFRNHFCITFELLGINLYELMKN-NNFQGFSLSIVRRFTLSVLKCL 218
Query: 122 AYCHAHRIIHRDLKPQNLLINRDG--NLKLGDFGLARAFGVPLRAYTHE-----IVTLWY 174
+IIH DLKP+N+++ + G ++K+ DFG + Y H+ I + +Y
Sbjct: 219 QMLSVEKIIHCDLKPENIVLYQKGQASVKVIDFGSS--------CYEHQKVYTYIQSRFY 270
Query: 175 RAPEVLLGGKQYSTGVDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTP------ 228
R+PEV+LG Y +D+WS+GCI AE+ PLF G++E++Q+ I VLG P
Sbjct: 271 RSPEVILG-HPYDVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLPPAGFIQ 329
Query: 229 ---------NERTWPDIIYLPDFKTTFPKWNRRNLSEVIPSLDANGIDLLDKLITYDPIH 279
+ + +P I K +P + ++L+ V+ + D + +D L + + ++P
Sbjct: 330 TASRRQTFFDSKGFPKNITNNRGKKRYP--DSKDLTMVLKTYDTSFLDFLRRCLVWEPSL 387
Query: 280 RISAKRAVQHPYFKE 294
R++ +A++H + +
Sbjct: 388 RMTPDQALKHAWIHQ 402
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 123 bits (308), Expect = 4e-28
Identities = 102/362 (28%), Positives = 173/362 (47%), Gaps = 87/362 (24%)
Query: 7 YKRLEKVGEGTYGVVY-------------KAVDLR----------HQNR------VVAMK 37
Y+ +EK+G G++G V K D+R HQN VVA+K
Sbjct: 38 YQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIK 97
Query: 38 KI--RLESEDEGVPSTAIREISLLKELK-DDNIVRLYDI-VHSDAHKLYLVFEFLDLDLK 93
+ +L + + T +REI + + +D++++++++ + S+ ++L++V E ++ +L
Sbjct: 98 TMMTKLHTLQD---YTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLY 154
Query: 94 RYME-------SIPKDQPLGGNIIKKFMMQLCKGIAYCHAHRIIHRDLKPQNLLI----- 141
+ M+ SIP +K + Q+ G+ + H H HRDLKP+N+LI
Sbjct: 155 QMMKHRRRRVFSIPS--------LKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQ 206
Query: 142 -------NRDGN-----LKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTG 189
N+ G +KL DFGLAR YT + T WYR+PE+LL YS
Sbjct: 207 YFEKEYMNQIGYQDNYVIKLADFGLARHVENK-NPYTAYVSTRWYRSPEILLRSGYYSKP 265
Query: 190 VDVWSIGCIFAEMCNRKPLFSGDSEIDQIFKIFRVLGTPNERT----------------W 233
+D+W+ GC+ E+ + LF G +EIDQI+KI VLGTP +R+ W
Sbjct: 266 LDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTNHITAPPPGGFW 325
Query: 234 PDIIYL-PDFKTTFPKWNRRNLSEVIPSLDANGI-DLLDKLITYDPIHRISAKRAVQHPY 291
D L P +L ++ S + + +++ K + +DP R +A+ + P+
Sbjct: 326 DDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPF 385
Query: 292 FK 293
F+
Sbjct: 386 FE 387
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.142 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,497,549
Number of Sequences: 60738
Number of extensions: 829704
Number of successful extensions: 7074
Number of sequences better than 1.0e-05: 1650
Number of HSP's better than 0.0 without gapping: 533
Number of HSP's successfully gapped in prelim test: 1117
Number of HSP's that attempted gapping in prelim test: 3484
Number of HSP's gapped (non-prelim): 1952
length of query: 295
length of database: 30,389,216
effective HSP length: 106
effective length of query: 189
effective length of database: 23,950,988
effective search space: 4526736732
effective search space used: 4526736732
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)