ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2579 check: MH R KOG1124 General function prediction only FOG: TPR repeat
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2579 893707 891845 -621
(621 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR320c_1 [R] KOG1124 FOG: TPR repeat 209 1e-53
YDR320c_2 [R] KOG0431 Auxilin-like protein and related proteins ... 119 2e-26
SPAC17A5.12_2 [R] KOG0431 Auxilin-like protein and related prote... 97 6e-20
SPAC17A5.12_1 [R] KOG1124 FOG: TPR repeat 77 1e-13
At1g21660 [R] KOG0431 Auxilin-like protein and related proteins ... 63 1e-09
At4g12780 [R] KOG0431 Auxilin-like protein and related proteins ... 62 3e-09
At4g12770 [R] KOG0431 Auxilin-like protein and related proteins ... 60 8e-09
At1g75100 [R] KOG0431 Auxilin-like protein and related proteins ... 59 3e-08
Hs7662146_2 [R] KOG0431 Auxilin-like protein and related protein... 58 5e-08
At1g75310 [R] KOG0431 Auxilin-like protein and related proteins ... 56 2e-07
Hs4885251_3 [R] KOG0431 Auxilin-like protein and related protein... 53 2e-06
CE27221 [R] KOG0431 Auxilin-like protein and related proteins co... 52 3e-06
7296894_3 [R] KOG0431 Auxilin-like protein and related proteins ... 52 3e-06
>YDR320c_1 [R] KOG1124 FOG: TPR repeat
Length = 519
Score = 209 bits (532), Expect = 1e-53
Identities = 166/539 (30%), Positives = 248/539 (45%), Gaps = 88/539 (16%)
Query: 1 MSDPFADLLSSFKGVXXXXXXXXXXXXXXXXXXXXXXHSALTSPLSRKSPS--------- 51
MSDPFA LL+S K S T+P S SPS
Sbjct: 1 MSDPFAHLLTSLKNKDSASA------------------SKETTPQSSNSPSITGSAVADV 42
Query: 52 ----NVPSKTPESISITSMTASQ--DFFDDLLAAPSQVTPLRESPSQVAPSTATEKDDFD 105
P+ + SIS + S DF L + T + + + A DDF+
Sbjct: 43 ARTDKSPNDSLHSISAPPLIPSPKVDFSAPPLVPTNSTTKSNTANNTPPSALANTDDDFN 102
Query: 106 LAFESFNST-------PHVDLVXXXXXXXXXXX-XLVDEVKDMEIARLMSLGLSFDKAVH 157
F T P D LVDEVKDMEIARLMSLGLS ++A
Sbjct: 103 QLFGMGTVTTTDTIQKPDEDYYGSKEDHLYNGDDALVDEVKDMEIARLMSLGLSIEEATE 162
Query: 158 YYDKGIMYEELIESQKKRKQSRSNVNNDFGQQQLRKQES-------RDSSPAFISVASNL 210
+Y+ + YE +E K +++ R+++ + ++ ++S DS+ F S+A++
Sbjct: 163 FYENDVTYERYLEILKSKQKERNDLAIRKKESGIKMEKSGLSNIVGTDSNNLF-SMATDF 221
Query: 211 FNMGKEFIEDKLKPTLQPQYANSSQRSQFSDDIPLRRDYTRP--HSRPHSMQFQSERT-- 266
FN GK+ ++ T P AN + + +S DY P + P+ + F+
Sbjct: 222 FNKGKKLVDQW---TSFPPEAND-RLNNYSKTHDKVEDYDLPQVNDSPNRILFEDNEVVE 277
Query: 267 ----SPQPSPELPSIHQLSINNASSAPPPVSVENQDTASVINQE-----------TLVDF 311
+ P +L + + I+ P VS + T+ ++ +E +L+DF
Sbjct: 278 NLPPADNPDQDLLTDFETKIDITKRTAPDVSHSSSPTSGILIEENSRRNEPLIEDSLLDF 337
Query: 312 GAAPQTSASPQHR---------------ISDFELTSFNEFKNNGVKYFSSGDYHNALLEF 356
T++ ISD EL+ +NEFK G F +GDY N+L E+
Sbjct: 338 SEGNLTNSKSNEDSTLFNENSNTDSTIPISDIELSGYNEFKAKGTSLFKNGDYINSLQEY 397
Query: 357 EKSFNTLPFKHPLRIISLSNIVSCQLKLGENSKALESVKLALDL-SDLAPNASDIIEHSV 415
EKS NTLP HPLRII+LSNI++ QLK+GE SK++E+ +AL+L + I +S
Sbjct: 398 EKSLNTLPLNHPLRIIALSNIIASQLKIGEYSKSIENSSMALELFPSSKAKWKNKISNSD 457
Query: 416 PERTFKQMINKIQLKHAEIQEHLENYEKALSLYANLISNGITEQKVMDGKRRCEKIVNP 474
PER+F + KI ++ AE EHLE+++KAL Y LI + K+M GKRRC+ +NP
Sbjct: 458 PERSFNDIWPKIMIRRAESFEHLESFKKALETYQELIKKNFFDDKIMQGKRRCQDFINP 516
>YDR320c_2 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 149
Score = 119 bits (297), Expect = 2e-26
Identities = 55/91 (60%), Positives = 70/91 (76%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLWWASWKEVSPQDLVMTKKVKICYLKAIAKTHPDKIP 590
KIS W ++D+R+LLANL LL W +WK+VS QDLVM K+VKI Y+KA+AKTHPDKIP
Sbjct: 58 KISSWKDGKDDDIRHLLANLSSLLTWCNWKDVSMQDLVMPKRVKITYMKAVAKTHPDKIP 117
Query: 591 ADASLETIMIAENVYTILNKAWEYFKSQNNI 621
SLE MIAEN+++ L+ AW+ FK QN+I
Sbjct: 118 ESLSLENKMIAENIFSTLSIAWDKFKLQNDI 148
>SPAC17A5.12_2 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 147
Score = 97.4 bits (241), Expect = 6e-20
Identities = 43/91 (47%), Positives = 68/91 (74%), Gaps = 1/91 (1%)
Query: 532 ISEWTKNNENDLRYLLANLEPLLW-WASWKEVSPQDLVMTKKVKICYLKAIAKTHPDKIP 590
+++W + E++LR LLA+L+ +LW W++VS +LV+ KKVKI Y+KA+++ HPDK+P
Sbjct: 57 VNKWKEGKESNLRALLASLDTILWPECRWQKVSLSELVLPKKVKIAYMKAVSRVHPDKLP 116
Query: 591 ADASLETIMIAENVYTILNKAWEYFKSQNNI 621
S+E +IAE+ ++ILN AWE FK QN++
Sbjct: 117 QQTSVEHQLIAESAFSILNHAWELFKQQNDL 147
>SPAC17A5.12_1 [R] KOG1124 FOG: TPR repeat
Length = 550
Score = 76.6 bits (187), Expect = 1e-13
Identities = 81/349 (23%), Positives = 155/349 (44%), Gaps = 44/349 (12%)
Query: 150 LSFDKAVHYYDKGIMYEELIESQKKRKQSRSNVNNDFGQQQLRKQESRDSSPAFISVASN 209
L D A Y +G YE +S K + S ++ QL+ Q A++
Sbjct: 219 LEKDNAKGQYREGEAYEAFSDSSAKTQFSDFQALSN----QLKSQ--------LFEKAND 266
Query: 210 LFNMGKEFIEDKL------KPTLQPQYANSSQ---RSQFSDDIPLRRDYTR-PHSRPHSM 259
L+N+G++ + D + K +P++ ++S R + +P R PH P +
Sbjct: 267 LWNIGRKKLRDAVEERRAVKDPSKPRWMDASHDFGREATPEILPKTPIPKRKPHKVPMNE 326
Query: 260 QFQSERTSPQPS----PELPSIHQLSINNASSAPPPVSVENQDTASVINQETLVDFGAAP 315
+ +R + S E + L+ + +S+ S + T +++ ET + A
Sbjct: 327 KVSEDRITTNQSRSGNDESSLVDFLTSKSDNSSFNFPSDTYEGTENIL--ETAYESTTAR 384
Query: 316 QTSASP----------QHRISDFELTSFNEFKNNGVKYFSSGDYHNALLEFEKSFNTLPF 365
Q + + + +++ E ++ G + F GD+ A+ EF S + LP
Sbjct: 385 QVNNNKPGKSTVKKREEETLNNMVSALVEEQQSTGNELFRKGDFSQAIEEFTNSLSQLPA 444
Query: 366 KHPLRIISLSNIVSCQLKLGENSKALESVKLALD-LSDLAPNASDIIEHSVPERTFKQMI 424
KH R+ LSN C K+G+ L+ V +D + + + I + S+ + K M+
Sbjct: 445 KHTKRVPLLSNRSLCYQKVGDLKTCLQDVDELVDIIGEEKGHGESIRDKSMNDYYVKNMV 504
Query: 425 NKIQLKHAEIQEHLENYEKALSLYANLISNGITEQKVMDGKRRCEKIVN 473
K A++ E LE Y+++L+++ +LI++G + +DGK RCE ++
Sbjct: 505 RK-----AQVLEQLEKYQESLNIWKDLIADGQISKLYIDGKHRCEAAIS 548
>At1g21660 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 523
Score = 63.2 bits (152), Expect = 1e-09
Identities = 35/90 (38%), Positives = 49/90 (53%), Gaps = 2/90 (2%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLW-WASWKEVSPQDLVMTKKVKICYLKAIAKTHPDKI 589
+I W E ++R LL++L +LW W+ VS DL+ + VK Y KA HPDK+
Sbjct: 431 EIRRWATGKEGNMRALLSSLHIVLWPGCGWEAVSITDLITSSAVKKVYRKATLYVHPDKV 490
Query: 590 -PADASLETIMIAENVYTILNKAWEYFKSQ 618
A+LE IAE V+ IL +AW F +
Sbjct: 491 QQKGATLEQKYIAEKVFDILKEAWNKFNKE 520
>At4g12780 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 924
Score = 61.6 bits (148), Expect = 3e-09
Identities = 35/90 (38%), Positives = 49/90 (53%), Gaps = 2/90 (2%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLW-WASWKEVSPQDLVMTKKVKICYLKAIAKTHPDKI 589
+I W E +LR LL+ L+ +LW W+ VS DL+ VK Y KA HPDK+
Sbjct: 832 EIKRWGAGKEGNLRALLSTLQYVLWPECGWQPVSLTDLITAASVKKVYRKATLCIHPDKV 891
Query: 590 -PADASLETIMIAENVYTILNKAWEYFKSQ 618
A+L+ IAE V+ +L +AW F S+
Sbjct: 892 QQKGANLQQKYIAEKVFDMLKEAWNKFNSE 921
>At4g12770 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 909
Score = 60.5 bits (145), Expect = 8e-09
Identities = 35/90 (38%), Positives = 49/90 (53%), Gaps = 2/90 (2%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLW-WASWKEVSPQDLVMTKKVKICYLKAIAKTHPDKI 589
+I W E +LR LL+ L+ +LW W+ VS DL+ VK Y KA HPDK+
Sbjct: 817 EIRRWGAGKEGNLRALLSTLQYVLWPECGWQPVSLTDLITGASVKKVYRKATLCIHPDKV 876
Query: 590 -PADASLETIMIAENVYTILNKAWEYFKSQ 618
A+L+ IAE V+ +L +AW F S+
Sbjct: 877 QQKGANLQQKYIAEKVFDMLKEAWNKFNSE 906
>At1g75100 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 651
Score = 58.5 bits (140), Expect = 3e-08
Identities = 30/89 (33%), Positives = 50/89 (55%), Gaps = 2/89 (2%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLWWAS-WKEVSPQDLVMTKKVKICYLKAIAKTHPDKI 589
KI +W+ ++R LL+ L+ +LW S WK V D++ V+ Y +A+ HPDK+
Sbjct: 559 KIRKWSSGKSGNIRSLLSTLQYILWSGSGWKPVPLMDMIEGNAVRKSYQRALLILHPDKL 618
Query: 590 -PADASLETIMIAENVYTILNKAWEYFKS 617
AS +AE V+ +L +AW++F +
Sbjct: 619 QQKGASANQKYMAEKVFELLQEAWDHFNT 647
>Hs7662146_2 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 265
Score = 57.8 bits (138), Expect = 5e-08
Identities = 32/90 (35%), Positives = 47/90 (51%), Gaps = 5/90 (5%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLWWAS--WKEVSPQDLVMTKKVKICYLKAIAKTHPDK 588
KI EW + E ++R LL+ + +LW WK V DLV ++VK Y KA+ HPDK
Sbjct: 173 KILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDK 232
Query: 589 IPADASLETIMIAENVYTILNKAWEYFKSQ 618
+ A+ ++ LN AW F++Q
Sbjct: 233 ATGQPYEQ---YAKMIFMELNDAWSEFENQ 259
>At1g75310 [R] KOG0431 Auxilin-like protein and related proteins containing DnaJ
domain
Length = 1448
Score = 55.8 bits (133), Expect = 2e-07
Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Query: 532 ISEWTKNNENDLRYLLANLEPLLWWAS-WKEVSPQDLVMTKKVKICYLKAIAKTHPDKI- 589
+ W+ EN+LR L++ L+ +L S WK + DLV + V+ Y KA HPDK+
Sbjct: 1358 VKRWSSGKENNLRALISTLQYILGAESGWKPIPLTDLVSSASVRKAYRKATLYVHPDKLQ 1417
Query: 590 PADASLETIMIAENVYTILNKAWEYF 615
AS + I E V+ +L +AW F
Sbjct: 1418 QRGASTQQKYICEKVFDLLKEAWNKF 1443
>Hs4885251_3 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 231
Score = 52.8 bits (125), Expect = 2e-06
Identities = 30/92 (32%), Positives = 48/92 (51%), Gaps = 5/92 (5%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLW--WASWKEVSPQDLVMTKKVKICYLKAIAKTHPDK 588
K+ +W + E ++R LL+ L +LW + W V DLV ++VK Y +A+ HPDK
Sbjct: 139 KLLDWIEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVAPEQVKKHYRRAVLAVHPDK 198
Query: 589 IPADASLETIMIAENVYTILNKAWEYFKSQNN 620
A A+ ++ LN AW F++Q +
Sbjct: 199 A---AGQPYEQHAKMIFMELNDAWSEFENQGS 227
>CE27221 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 784
Score = 52.0 bits (123), Expect = 3e-06
Identities = 32/92 (34%), Positives = 49/92 (52%), Gaps = 7/92 (7%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLWWAS--WKEVSPQDLVMTKKVKICYLKAIAKTHPDK 588
+I +WT+ E ++R LL +L +LW + W + S DL+ ++K Y KA HPDK
Sbjct: 694 QIRDWTQGKERNIRALLGSLHNVLWEGADRWNQPSMGDLLTPDQIKKHYRKACLVVHPDK 753
Query: 589 IPADASLETIMIAENVYTILNKAWEYFKSQNN 620
+ L +A+ +T LN A Y K QN+
Sbjct: 754 LTGSPHLS---LAKMAFTELNDA--YSKYQND 780
>7296894_3 [R] KOG0431 Auxilin-like protein and related proteins containing
DnaJ domain
Length = 449
Score = 52.0 bits (123), Expect = 3e-06
Identities = 29/88 (32%), Positives = 45/88 (50%), Gaps = 4/88 (4%)
Query: 531 KISEWTKNNENDLRYLLANLEPLLW-WASWKEVSPQDLVMTKKVKICYLKAIAKTHPDKI 589
+I EWT +N++R LL ++ +LW A W+ +V +VK Y +A HPDK
Sbjct: 355 RIMEWTDGKKNNIRALLCSMHTVLWDNAKWQRCEMSTMVTPTEVKKAYRRACLAVHPDK- 413
Query: 590 PADASLETIMIAENVYTILNKAWEYFKS 617
E IA+ ++ LN AW F++
Sbjct: 414 --HNGTENEEIAKLIFMELNNAWTDFEN 439
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.128 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,356,111
Number of Sequences: 60738
Number of extensions: 1441303
Number of successful extensions: 4940
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 4911
Number of HSP's gapped (non-prelim): 23
length of query: 621
length of database: 30,389,216
effective HSP length: 112
effective length of query: 509
effective length of database: 23,586,560
effective search space: 12005559040
effective search space used: 12005559040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)