ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2608 suspect: Pn S KOG4674 Function unknown Uncharacterized conserved coiled-coil protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2608 902691 904529 613
(613 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 53 1e-06
7292701_2 [S] KOG4415 Uncharacterized conserved protein 52 3e-06
Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription fact... 50 8e-06
Hs4503509 [J] KOG2072 Translation initiation factor 3 subunit a ... 50 8e-06
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 53.1 bits (126), Expect = 1e-06
Identities = 75/356 (21%), Positives = 139/356 (38%), Gaps = 73/356 (20%)
Query: 63 YQTKSQSTNMRLLNKYFYGDPNVIEEVKK------RERKAL--------KDIHLFTKQIE 108
Y ++ + +LNKY DP +EE+KK +E++ L K+ F +Q+
Sbjct: 1331 YNSRWKLRFQSVLNKYERVDPTQLEELKKNCEALEKEKQELETKLQETAKETDTFKQQVN 1390
Query: 109 ETDSRLESLTSEVIP-------------QLKYNLNKRSII-FKHLKQETMVMQEQLYQLK 154
+ +E+L EV + NL K S+ F HLKQ
Sbjct: 1391 SLNEEVENLKKEVEQANTKNTRLAAAWNEKCENLKKSSLTRFAHLKQ------------- 1437
Query: 155 NDCELKKKNHELITNNLNLEHSINIQEVINQWQLKISDKRHIWELELQKLKQTKPDPAVL 214
EL KN EL + N E + + + D H +LQ+ + +
Sbjct: 1438 ---ELTNKNKELTSKNAE-------NEAMQKEIESLKDSNH----QLQESASSDAEQITK 1483
Query: 215 KEIEELSTDKAIIENDLKDLKRK-NHEQIQSYENELKLRLEKFKED------KKEPLIAS 267
++ E+L ++K E +L D K + H Q ++ + + K + +++ KE L+
Sbjct: 1484 EQFEQLKSEKERTEKELADSKNELEHLQSEAVDADGKTEISNLEKEIHELRSDKEGLVQQ 1543
Query: 268 IXXXXXXXXXXXXXXATQEALRD-----KIRNSVDTELSLQEIIKNKRLELQTLEASLEP 322
+ TQ +L + ++R+ +++ E K K E+ + L
Sbjct: 1544 VQNLSAELAALREHSPTQGSLENADEIARLRSQLESTKQYYE--KEKETEILAARSELVA 1601
Query: 323 VEEKLN---QLQLRYKSEKDTTDXXXXXXXXXXXXYNKNYDRMEQEQSQRRILENT 375
+EK + QL KS++ + + N D M ++Q + ++ EN+
Sbjct: 1602 EKEKTKEELENQLNEKSQR-IKELEEQAQKNSSENTHDNIDDMIKQQVEEKLKENS 1656
>7292701_2 [S] KOG4415 Uncharacterized conserved protein
Length = 1643
Score = 51.6 bits (122), Expect = 3e-06
Identities = 67/277 (24%), Positives = 128/277 (46%), Gaps = 33/277 (11%)
Query: 88 EVKKRERKAL-----KDIHLFTKQIEET--DSRLESLTSEVIPQLKYNLNKRSIIFKHLK 140
++K++ER+A K+ L K+ EE+ R E L E I + + + K +
Sbjct: 732 KLKEKEREAKLQEKEKEEKLKLKEREESLRMEREEKLKEEKIKEKEREEKLKEEKIKEKQ 791
Query: 141 QETMVMQEQLYQLKNDCELKKKNHELITNNLNLEHSINIQEVIN-QWQLKISDKRHIWEL 199
+E + +E+L + + + +K+K E E + +++ + + K+ +K L
Sbjct: 792 REEKLKEEKLKEKEREERMKEKEREEKAKEKQREEKLREEKIKEKEREEKLKEK-----L 846
Query: 200 ELQKLKQTKPDPAVLKEIEELSTDKAIIENDLKDLKRKNHEQIQSYENELKLRLEKFKED 259
+K+K+ + + + KE EE +K E + K +++ E+I+ E E KL+ EK ++
Sbjct: 847 REEKIKEKEKEEKLRKEREEKMREK---EREEKIKEKERVEKIKEKEREEKLKKEKEEKL 903
Query: 260 K-KEPLIASIXXXXXXXXXXXXXXATQEALRDKIRNSV---DTELSLQEIIKNKRLE--- 312
K KE L+ QE L++K R +TE +E + ++L+
Sbjct: 904 KEKEELLKKKEKEEKEREEKLKEKERQEKLKEKEREEKLKRETEERQREKEREEKLKEKE 963
Query: 313 ----LQTLEASL------EPVEEKLNQLQLRYKSEKD 339
L+ LE + E ++EK +L+L+ K EKD
Sbjct: 964 RAEKLKDLEKEVKLKEKEEQLKEKEKELKLKEKKEKD 1000
>Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription factor interacts
with stathmin
Length = 1591
Score = 50.4 bits (119), Expect = 8e-06
Identities = 61/275 (22%), Positives = 127/275 (46%), Gaps = 40/275 (14%)
Query: 84 NVIEEVKKRERKALKDIHL----------------FTKQIEETDSRLESLTSEVI--PQL 125
N+IE+VK LK+ H K+ EE +++++ L E++ ++
Sbjct: 846 NIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEV 905
Query: 126 KYNLNKRSIIFKHLKQETMVMQ----EQLYQLKN-----DCELK--KKNHELITNNLNLE 174
N + + KH K+ + +Q ++L +++N +CE+K K++ E++ +L
Sbjct: 906 LQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKL 965
Query: 175 HSINIQEVINQWQLKISDKRHIWELELQKLKQTKPDPAVLKEIEELSTDKAIIENDLKDL 234
H N +++ QL ++ + + + L++L+ T ++E E++ TD + L++L
Sbjct: 966 HVENDEKL----QLLRAELQSLEQSHLKELEDTL-QVRHIQEFEKVMTDHRV---SLEEL 1017
Query: 235 KRKNHEQIQSYENELKLRLEKFKEDKKEPLIASIXXXXXXXXXXXXXXATQEALRDKIRN 294
K++N +QI + E + + KE + + L + A +EA D+I+
Sbjct: 1018 KKEN-QQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKI 1076
Query: 295 SVDTELSLQEIIKNKRLELQTLEASLEPVEEKLNQ 329
++ + Q+ LE +T +L KLNQ
Sbjct: 1077 LLEESRAQQKETLKSLLEQET--ENLRTEISKLNQ 1109
>Hs4503509 [J] KOG2072 Translation initiation factor 3 subunit a (eIF-3a)
Length = 1382
Score = 50.4 bits (119), Expect = 8e-06
Identities = 69/308 (22%), Positives = 129/308 (41%), Gaps = 23/308 (7%)
Query: 91 KRERKALKDIHLFTKQIEETDSRLESLTSEVIPQLKYNLNKRSIIFKHLKQETMVMQEQL 150
K RK + I + IEE RLESL I + K L +R L++ +E+L
Sbjct: 559 KNSRKEHQRILARRQTIEERKERLESLN---IQREKEELEQREA---ELQKVRKAEEERL 612
Query: 151 YQLKNDCELKKKNHELITNNLNLEHSINIQEVINQWQLKISDKRHIWELELQKLKQTKPD 210
Q E K++ E I ++E + Q + + +++++ L++ PD
Sbjct: 613 RQ-----EAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPD 667
Query: 211 PAVLKEIEELSTDKAIIENDLKDLKRKNHEQIQSYENELKLRLEKFKEDKKEPLIASIXX 270
+ K++E+L +K ++ LK+ ++K I +E RLE+ K I
Sbjct: 668 FIMAKQVEQLEKEKKELQERLKNQEKK----IDYFER--AKRLEEIPLIKSAYEEQRIKD 721
Query: 271 XXXXXXXXXXXXATQEALRDKIRNSVDTELSLQEIIKNKRLELQTLEASLEPV-EEKLNQ 329
T + R+K +++ + + +++++ L + L+A+ + V EEKL Q
Sbjct: 722 MDLWEQQEEERITTMQLEREK---ALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQ 778
Query: 330 LQLRYKSEKDTTDXXXXXXXXXXXXYNKNYDRMEQEQSQRRILENTIDELDGHIRCFAYL 389
+ R E+ + Y R ++E+ QRR E + E + R
Sbjct: 779 FEERLAEERH--NRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAK 836
Query: 390 NYDELNDY 397
+EL +Y
Sbjct: 837 REEELREY 844
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,402,343
Number of Sequences: 60738
Number of extensions: 1327304
Number of successful extensions: 6013
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 5991
Number of HSP's gapped (non-prelim): 18
length of query: 613
length of database: 30,389,216
effective HSP length: 112
effective length of query: 501
effective length of database: 23,586,560
effective search space: 11816866560
effective search space used: 11816866560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)