ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2688 good S KOG1910 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2688 924069 931955 2629
(2629 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR454w [S] KOG1910 Uncharacterized conserved protein 1504 0.0
SPAC3H5.09c [S] KOG1910 Uncharacterized conserved protein 503 e-141
YPR117w [S] KOG1910 Uncharacterized conserved protein 436 e-121
>YLR454w [S] KOG1910 Uncharacterized conserved protein
Length = 2628
Score = 1504 bits (3895), Expect = 0.0
Identities = 895/2674 (33%), Positives = 1420/2674 (52%), Gaps = 176/2674 (6%)
Query: 39 GIYVLGFNPLTLKLQRIRIKD-KLWIKSIRYDAFKHQLIIDTVEWIGKVQSKDGDTDDKT 97
GI + N L++ + ++D + +KS+R+ F+ +L I + ++ SK T+D
Sbjct: 32 GINITWINLFKLEICGLSLEDGTVRLKSVRFAVFERKLFIKGL----RIDSKKSSTNDL- 86
Query: 98 NDSQQLHGPSEEDLKDETCKLLSRTLTRYLPFMSKWLDRVXXXXXXXXXXXXXXNFTLIK 157
++L E + +++ L WL+ V
Sbjct: 87 --HKELPREEERTFIETPEDNGGGFISKILSLSQYWLNGVTIILEDTQLVNNDITIEKFG 144
Query: 158 IF------SEGNEFAFEVNLQSVMLKEKQMVANTIFKSDAMMDL-ERPFPLND---ININ 207
F F+ L+ ++ + ++A+ IF + + + E PL D + ++
Sbjct: 145 FFLSIDNSKHIKSLRFDSFLRKLLWNGQTIIADAIFIVNTNLLIGEIMNPLKDGLQVGLD 204
Query: 208 LKMREMTVPVSSFIIAVYQLRHGKIPDQLDKVKKDPLYEGLPPIKSPESTIHDEEFPS-E 266
LK+ ++ +P++ + + + + +D + + L + L + DE+ +
Sbjct: 205 LKLGDLNIPMNLLNLFINK-------ENVDLMSNEKLLQRLADTTKANEELKDEDIAKMK 257
Query: 267 WNIEQVMEKFQKKFERFYDISSSFEKIEIHFDSPLFTEIPFKSNLELIQKTEAIQFEVTT 326
++ MEKF + + +++ + +K++I + P ++ EL+ + I + V
Sbjct: 258 DDLVYAMEKFVDRIKPLKEMNVTVDKLQIK-------DFPLTNHPELLGMNKYISYNVLV 310
Query: 327 TGIALSLSRSAFSEPGNKLLFDIDERPVKISTFITQLKLSIITQKDGSKNRLENRICEIP 386
+ I + +R PG L+F+ + P K S + + + + + + + +I EIP
Sbjct: 311 SNINFNTNRFRNEMPGYTLIFEERDSPFKFSIIMARFNIYLNLNRKHQSHAKQLKIIEIP 370
Query: 387 SISFYGDSNLFCTRSFGPDD--SKVFANTILKLFGHVTSPIFDIDIENLSLLISVERNLK 444
++S +G++NLF + ++ +K N I + G+++S D+D N+S + N+K
Sbjct: 371 NVSIFGETNLFSQKFRLSNNLHAKELENAIFNIKGNISSLTIDMDPVNISFIKCFLSNIK 430
Query: 445 VLEDLISDNPIKEPLDLNQIYNKITRKGKFLEYFQNYLPHTELKFTIEDPIIIVSNQLDS 504
V N I L N +TR+ +YF+ +LP +KFT++DP +++++ D
Sbjct: 431 VFTSSCPKNKI---LKENSHVKFLTRRRVLFDYFKCFLPLINMKFTLDDPKFVINDKDDL 487
Query: 505 LIHKFSMISFKIKSDRLYIK---AEEK-----LFYSLDTHLEISEWLFYHQNKNKLLKNA 556
+I KFS+ S R + EEK +FY ++E+ + H K++ ++
Sbjct: 488 IIGKFSVFMISHHSKRYTLGNNLMEEKEETQHIFYESHWNVELLDMKLQHIIKHQKYEHT 547
Query: 557 IFSVDSTIFRFNTRILPSLLLSSIVEINTVRLDLTNLETLVVINNTIRQRTMKLLYVEGK 616
I VDS ++LP +L S+ +I+T+ LDL+ L T+V+++ + +L VE
Sbjct: 548 ILRVDSIAIEEKVQLLPDILCSANADIDTLMLDLSELPTMVMLSELVHNLDSQLANVEEN 607
Query: 617 YFKDIFHHLESRLM---AKVEYFKKNQTNTSALDVEEFLFKDIPSFFQYLKLYVKDFEAN 673
YFK+ + S L A+ K L +F+F+ +P FF Y+K+ ++D +
Sbjct: 608 YFKEFYEKFASNLQNMKAECSNMAKCLRQKEILP-SDFMFQQLPDFFDYIKINIRDISST 666
Query: 674 LGFRSVFIERNDYINRDFETIHDFISGDMRKISYLFKELKV-LFAKENXXXXXXXXXXXX 732
LG RSVF+ R+ + + D ++ D I G +RK ++L++ LF +
Sbjct: 667 LGARSVFMPRDVFSSVDSQSSKDLIDGKLRKYCNTVEKLQIALFGDKTQWHNKIGSNHAT 726
Query: 733 XXXXXXXXLASDD-----------MGLGSVTAEQSDSEPSSWSLALDLSDFNTDLFSETQ 781
S D L ++ + W++ L ++D T + ET
Sbjct: 727 MVRSGQLTNFSKDNKQNPNHKSSIADLDDISTSDATEVNHLWNINLLVNDITTSIIGETP 786
Query: 782 KDNFKLISKPVFKLPSFKMFVCPDHE-------EKRIKTSIHVSNVDLLFSLMTTFQFVS 834
+ + +L +K V K+ + + + PD E + +I I+ S + SLM+ F VS
Sbjct: 787 EVSEELSTKTVSKVSNLSIKLFPDTESFSSNESDSKIILQINHSRGTSVVSLMSIFLAVS 846
Query: 835 SIYNLKMVFKTDLYGSTKECLVSKHIQTIKQLKKHSLISYDKHALL-QLIELECSFDSIN 893
I+ L +F ++ ++ ++ + + KK S I K L +L+E+ S + I+
Sbjct: 847 GIHTLNQIFGHCIHQKMRQSKTKQYFLALSESKKKSCIKSIKWGQLKELLEINFSSEYIS 906
Query: 894 STMLLPNGVRTKLELVNPSFAFTCPHLIKMEGHYARLMVESPILKNTWMRMVSIVNFTIA 953
+ LPNG+RTK E + + I + G Y R+MVESP N W RM+ I F +
Sbjct: 907 QIIALPNGLRTKFEPTSTFITVKNCNTISVSGQYFRMMVESPTQPNFWERMICINGFKVM 966
Query: 954 VDVPIMLEKGDK-----------AGITLSNETWQWAIPHRFEMYKLFDNISTTFKSIKQM 1002
+ + ++ ++ K + ITL N++W ++IPH FEM+K+ D+I T FKSIKQM
Sbjct: 967 IHIDLLKQQMKKLNSLQNWEKLPSAITLENDSWHFSIPHHFEMFKIIDSIPTIFKSIKQM 1026
Query: 1003 LHSLASESNESVIYP-KVTKFIAIPKIKVKSSRWIFSVEDDPFESELNLLLQIGLREQKE 1061
L+SL + ++ +I+P K+ +++PKIK+KS RW+FS+ DDP E+ELN + QIGL+EQ+E
Sbjct: 1027 LYSLKTSKDDLIIFPHKIETPLSLPKIKLKSKRWLFSISDDPLEAELNTIFQIGLQEQRE 1086
Query: 1062 RLEKYNIFRKRVEMELKKPQV-----------------------------KNLRKSASFT 1092
RL K F KR+ +L K Q K LRKSA+ +
Sbjct: 1087 RLAKLQEFNKRISEDLIKSQKNAKEMKDDFEAIDNAILKHRTGLWAKDGKKRLRKSATDS 1146
Query: 1093 SKNTVPXXXXXXXXXXXXXXMIGFDSYDFDGADGMTEQLKEEYERLTRHISKSWITRVKK 1152
P F S + + A Y L + S SWI RVK+
Sbjct: 1147 EIPLTPAALNINGKRDDRPDRTQFISPEIENA----------YNTLLANFSDSWIKRVKE 1196
Query: 1153 QRNLLKNHFSENFEFLWGKLDITKLPKDFNKNVLDFTSSPALMNLIFEDIDIDLSKPSFG 1212
+ + F +NF FLWG +D TKLPKD NK VL F+++P LMNLI E+IDID+ +PS G
Sbjct: 1197 YKVKERREFDKNFSFLWGFIDYTKLPKDINKKVLPFSTNPFLMNLIIENIDIDIIRPSCG 1256
Query: 1213 VENIPDFIHDVGKKVPKDTKYSIMIPLNLNANFSEIRCHLKDYPLPAVHFPKENADTKKP 1272
+ENIP+FIHDVGK VPK+T+YSIMIP++L+A FSE+R HL+DYPLP V P ++ K
Sbjct: 1257 IENIPNFIHDVGKGVPKNTEYSIMIPMHLDAKFSEVRWHLRDYPLPFVSIPPLSSTQSKE 1316
Query: 1273 TTNLKC--DLLITEDMIHSDKELRTIYVPLVPSAHLEDSESLYSLLIPRTLTAIKLFTDI 1330
T ++ D +ITEDM+ SD+ELRT++VPL+PS +E+++ YSL +PRT+T+ K+FTD+
Sbjct: 1317 TIPMRIYGDFMITEDMLQSDRELRTLFVPLIPSVTVENTDRYYSLFVPRTMTSAKIFTDL 1376
Query: 1331 QLDITSSDNVRFVWGGSYSGAIQQTMKCFDNFSKPPIDPSPAVGFWDKIRNIFHARISIN 1390
+I S+ R WGGSY AIQQTM+C DNFSKPP+DPS +GFWDK R +FH +I+I
Sbjct: 1377 NFEINSNHTTRVTWGGSYQPAIQQTMQCLDNFSKPPLDPSVKLGFWDKTRYLFHGKINIV 1436
Query: 1391 LPN-SCFEVALKGDKNPYKIGGMSAGYALIFKDNVKIFCNKNDNPQKFLTVTASELSFSI 1449
FE++LKG K+PY +GG SAG+ + F NV + CN++++P+KFL+ +A ++ FSI
Sbjct: 1437 WKKRGKFEISLKGAKSPYMLGGESAGFIVGFDGNVNLKCNEDNDPKKFLSCSADKVHFSI 1496
Query: 1450 PNFFAKPLPVWNVPSEQSLFFPVEEFSNLQENAAFYYLLESAKMPKDKKDIEIMSKAYIE 1509
PN+FAKPL VW+ PS ++F P ++ +N+Q A+FYYLL + +K D EIM K++IE
Sbjct: 1497 PNYFAKPLLVWSRPSTNTMFIPNQDDTNMQRYASFYYLLNTTSSKNEKADKEIMGKSFIE 1556
Query: 1510 KTAIMLTGGMQFNVGIMFERQNKETNKRTFELKPHYEFRLCNPIYVPKSEDHDSYAGFRS 1569
KT I L+GGM ++GI+FER N+RTFE K HY RLCNPIYV HDSYAGFRS
Sbjct: 1557 KTGIKLSGGMTLDMGILFERLGPSLNERTFESKKHYLTRLCNPIYVQDLSKHDSYAGFRS 1616
Query: 1570 DFIHLSFDLISKSEDAYNCMQLTPNAFKIFFKWWSTFSGNLPVRKGPLFSDERFSPKFGT 1629
DFIH+SF L S S AYN MQL+PN FK FF WW +FSGN PVR+GPLF + SPKFG
Sbjct: 1617 DFIHMSFGLSSNSNSAYNAMQLSPNGFKAFFVWWKSFSGNFPVRRGPLFGLQSISPKFGE 1676
Query: 1630 HLYTISYRADVYPLFICHMVPGLDPKALVDSSV--NAEVFGLKAKMSEFSMDLHQRKEIF 1687
HLYTISY ADV PLFI +M D ++ + AE GLKAK S F MDLHQRKE+
Sbjct: 1677 HLYTISYHADVSPLFINYMYHNADADQILRKNYLEVAEFAGLKAKSSHFIMDLHQRKEVL 1736
Query: 1688 HEYKKQLQVTKRRASLKFFEAXXXXXXXXXXXXFASFSKAEY-AKTHSPDICIFDEDMTW 1746
EY+ L V +R LKF FSK Y + + IFD DM+W
Sbjct: 1737 TEYQAGLNVRRRVMKLKFLAGDVVCQDVDIRTVSGEFSKLNYIEEKEDAEYDIFDNDMSW 1796
Query: 1747 FDVDDFTEFNISNPGTLIPTVVVKPLLFSPMFAYKKIAPYGDKYQVDFETFEPIEPFNNA 1806
D+ DF + NP +P + + P FSP FAY+K A YGDKYQVD +T +PI PF+N
Sbjct: 1797 LDITDFQDAFFINPDNYLPKIKIMPFAFSPQFAYQKRASYGDKYQVDPKTCKPITPFDNR 1856
Query: 1807 RYHDCNLRKYVAIPDHLINDRHRIFAEEKSKLEEKVNDGNCTDNEKIELQERLEMIEKTI 1866
H C L V++ L+ R + + + KL+E + + L + L ++
Sbjct: 1857 VSHGCTLGHNVSLRTDLVEKRVTVLKKFREKLQEGIRKNKSAGVSEENLNDLLSKANSSV 1916
Query: 1867 AQLELMKTDINFLNSEYERADRESDVPDTSAEKLNLPILNFMKSSHNSNKNYANKFIVVS 1926
EL+ D + ++E E + + LN +K++ + K + ++F + +
Sbjct: 1917 ENAELLLKDFQKIFKQHEAGQTE--------QPFHFDSLNLLKNTKKTLKQFEHRFFIFN 1968
Query: 1927 MLLKWNEEVRNVFLKYMHRVSLLSDMNSVTKLKTLQTLDSLINKNRQSINTIAXXXXXXX 1986
+LLKWNE+ R+ K+ + +L ++ S+ K L+ + +I + + +T +
Sbjct: 1969 VLLKWNEDARSAIFKFFYYANLSNEFASLASGKGLREFEDVIKQREMTDDTTSMEAIPEG 2028
Query: 1987 XXXXXXXXQVFKSIFHEDKEPEEIVSSFQNDIKMLAGDFDYKTFEKHHVQLIAPQIQLTT 2046
Q S + E +++ F+ +I L+ D K K VQ I PQIQLT+
Sbjct: 2029 TDKANTTKQC-HSCDDTEFTTENLLNIFEKNITQLSCDIKNKIHHKFFVQFITPQIQLTS 2087
Query: 2047 ITDPDACILVTAPTIKINSLCFDSNTSGNEYQQNLFMRRTGVLLTNSNVFVFHKKEQGSY 2106
+ +P+AC+LV++P + +L FD+NT+ N Y Q++F++R G+L N+N F+F+KK+ +
Sbjct: 2088 LENPEACVLVSSPFFMLKTLEFDANTTSNTYMQDIFLKRHGILFGNANAFLFNKKDYQEF 2147
Query: 2107 GHLLFDNFLYGSTLETSWRPWLGLELCFNPENLTENMLISNFTSVFTYDQVLPFANIPDS 2166
L F + YG + W PWLGLEL F P L + ++ N +++ + ++ PF+ DS
Sbjct: 2148 FELYFGSSSYGQDKKEQWPPWLGLELGFEPSALKKKAVVRNISALLHHQKLAPFSAKYDS 2207
Query: 2167 LKDSNVLNNRISCDFPRIVIESNSARYISLFNLVTNLLLYVEPESAKMKDDIKKLVLSFN 2226
LKD + + I P++ ++ NS Y+ L + L LYVEPE ++K I+KL++ ++
Sbjct: 2208 LKDK--IEDNICGYVPQVNVQVNSDEYLMLTKMALKLFLYVEPEDEELKKYIEKLIIGYD 2265
Query: 2227 FEDLSIVKEMISVLEKEIDALNTLENEYSYRKYLLDDAEISDLNNIRYNKFDSIMKTHMI 2286
D + ++ ++ L L +E E +++ LLDD DL+NI + +++ +++
Sbjct: 2266 IYDTAQTRKFVNDLHDSEQILAVVEKELLFKRSLLDDIGKLDLSNIHNERMHQLLRLYIL 2325
Query: 2287 MKVLTSASPEQSNDEEMLLIVLKAKEIILHMLDDDGDNFLDVAVADMAFQRMETSSGYNF 2346
KV TS N L+ +K E ILH+LD FLD+AVA + FQR++ + G
Sbjct: 2326 RKVFTSNGNNYIN--RTLVWNIKVNETILHLLDKIDKPFLDIAVAKLNFQRIQHTMGLRK 2383
Query: 2347 NRMTVGIGQVINLSHDALFHDLLSPV------EKELTESSEPFIDLQWEKNKAVGGIQVV 2400
N +TV + Q+ +L + +H +L P+ + S P + + W+ +K VGGI+VV
Sbjct: 2384 NTVTVKMMQIFDLGENVNYHCILGPLITSSGNDTVGLASDVPLVQITWDVDKPVGGIKVV 2443
Query: 2401 KNVVTNLQTLKLNVEQSTIEKIIAWVSPSSVSLLIXXXXXXXXXXXXXXXLQXXXXXXXX 2460
KNV T L +L + +E+ + K+ W+S +
Sbjct: 2444 KNVETTLSSLTIKLEEDRLNKLFEWLSLKEL---------------------------IY 2476
Query: 2461 XXXXXXANGIQSQQYSIMQSPTELIFPVDDMLGNDMEMEEMIQRSKDNMIIENIKINSFL 2520
+G S + E + + +D EM++RS D MI+E++K+NSF
Sbjct: 2477 DGNGDDDDGASSIFDMVSSESEEGKIEFSEDISSD--FNEMLKRSSDYMIVEDLKLNSFK 2534
Query: 2521 MIISYQGTGAKRLINVTDFNLNFPLIRFTNQTMTMLDLMMHLKKVLIKSLLRHTGKFIGN 2580
+ ISY+G G RL NVT+F NFP +R +NQT+ + DL++ LKKVLIK L++HTG+FIGN
Sbjct: 2535 LCISYKGKGKMRLANVTNFVFNFPTLRLSNQTLRVTDLLLALKKVLIKVLIKHTGRFIGN 2594
Query: 2581 KLKKHRSVKRLRGAARSPLKQLNYYTHYTPVDEL 2614
KLK++ ++ SPLKQL Y YT +EL
Sbjct: 2595 KLKRNSKENKIADDT-SPLKQLTTYNSYTEPEEL 2627
>SPAC3H5.09c [S] KOG1910 Uncharacterized conserved protein
Length = 2685
Score = 503 bits (1296), Expect = e-141
Identities = 449/1825 (24%), Positives = 799/1825 (43%), Gaps = 169/1825 (9%)
Query: 895 TMLLPNGVRTKLELVNPSFAFTCPHLIKMEGHYARLMVESPILKNTWMRMVSIVNFTIAV 954
++LL G T L+ +A +M + ++ ++ + W R +++ N +
Sbjct: 789 SLLLDCGGFTTLKKTEKKYA-------EMHAKFIQIHTKNSDVPTLWDRFLALGNVRYQL 841
Query: 955 DVPIMLEKGDKAGITLSNETWQWAIPHRFEMYKLFDNISTTFKSIKQMLHSLASESNESV 1014
LEK + +T S + + IPH+F + L ++ T K+ ++ + +
Sbjct: 842 KDLSDLEKLHQ--VTCSYISIR--IPHKFIPFILIESAINTVKAAIRVSAEPLTIDQQHD 897
Query: 1015 IYPKVTKFIAIPKIKVKSSRWIFSVEDDPFESELNLLLQIGLREQKERLEKYNIFRKRVE 1074
+ ++ + +P I++KS+++ F V+DDPFE L + +IGL EQ+ R++++NIF +R
Sbjct: 898 LAEEIKQPRVVPHIQIKSTKFKFEVDDDPFECRLGMNYRIGLTEQQMRIDRWNIFEERAN 957
Query: 1075 M--ELKKPQVKNLRKSASF------------TSKNTVPXXXXXXXXXXXXXXMIGFDSYD 1120
+ + K P K+ +S+SF S NT + D
Sbjct: 958 LLRKAKDPSPKSASESSSFYQNGSDIDDNDSNSSNTSNHTTENANAQQRKLEDLNRSFED 1017
Query: 1121 FDGA---------DGMTEQLKEEYERLTRHISKSWITRVKKQRNLLKNHFSENFEFLWGK 1171
F G+ ++ E+L + S SWI+ +K+ R + W +
Sbjct: 1018 FLGSRPTNNSSFLKNVSVDEDTAREKLMEYDSLSWISNIKRIREFRYHRLRIRRMTAWPE 1077
Query: 1172 LDITKLPKDFNKNVLDFTSSPALMNLIFEDIDIDLSKPSFGVENIPDFIHDVGKKVPKDT 1231
D F +N++ P L+++ + D L KPSF +E +P F++ VG+ P D
Sbjct: 1078 SDALDKHILFKENIIPIPIRPPLVDISLLNFDFTLDKPSFPLEELPKFLNTVGRGQPLDY 1137
Query: 1232 KYSIMIPLNLNANFSEIRCHLKDYPLPAVHFPK--ENADTKKPTTNLKCDLLITEDMIHS 1289
YSI P+ ++ E + ++DYPLP V+ PK D + + +LK +++ITE +
Sbjct: 1138 GYSIYFPMYIDWKMDEAKFLIRDYPLPLVYIPKLGRGQDKRISSWHLKSNMVITEQQA-T 1196
Query: 1290 DKELRTIYVPLVPSAHLEDSESLYSLLIPRTLTAIKLFTDIQLDITSSDNVRFVWGGSYS 1349
+R + V ++P A L Y + + RT++ IK F+ ++D+ SS +W SY
Sbjct: 1197 LAAIRDVSVKVIP-ADLTKEGIPYVVNVTRTVSPIKTFSKTEIDVNSSLPTFLLWCNSYQ 1255
Query: 1350 GAIQQTMKCFDNFSKPPIDPSPAVGFWDKIRNIFHARISIN-LPNSCFEVALKGDKNPYK 1408
A+ + D F+K PIDPS +GFWDKIR + H++I + L + ++LKG ++PY
Sbjct: 1256 PALSDMTRIMDTFTKMPIDPSEKLGFWDKIRLVAHSQIRLRWLEDGDVFLSLKGSRDPYV 1315
Query: 1409 IGGMSAGYALIFKDNVKIFCNKNDNPQKFLTVTASELSFSIPNFFAKPLPVWNVPSEQSL 1468
I G AG+ + NV ++NP F+ V + + +IP+F P + + +
Sbjct: 1316 ILGEGAGFQFCWSGNVSWDIGCDENPANFMIVDSDKFYLTIPDF---PRQINGILEGK-- 1370
Query: 1469 FFPVEEFSNLQENAAFYYLLESAKMPKDKKDIEIMSKAYIEKTAIMLTGGMQFNVGIMFE 1528
P+ S + F L KD + ++++K L G +++ G + E
Sbjct: 1371 --PLPTKSTKRSYTTFGVL-------KDLRCRKVIAK---------LVGKVRWRAGFVPE 1412
Query: 1529 RQ--------NKETNKRTFELKPHYEFRLCNPIYVPKSED--HDSYAGFRSDFIHLSFDL 1578
R N++ R + KPH++ P Y + +D+Y FRS +IH S L
Sbjct: 1413 RHCDEDCTVCNRKKACRLWNFKPHWQVITRIPQYCHDTHYGVYDAYRDFRSHYIHCSLAL 1472
Query: 1579 IS----------KSEDAYNCMQLTPNAFKIFFKWWSTFSGNL--PVRKGPLFSDERFSP- 1625
S ++ ++YN + LTP F F WW+ FS N+ P+R G LF SP
Sbjct: 1473 ESPRYLDDANAFENVNSYNTIHLTPLVFSHFSSWWNLFSNNMSYPLRSGNLFPTLDSSPN 1532
Query: 1626 -KFGTHLYTISYRADVYPLFICHMVPGLDPKALVDSSVNAEVFGLKAKMSEFSMDLHQRK 1684
KFG HL T Y ++ PLFI HM K D + +A GLKA++ F++DLHQR
Sbjct: 1533 KKFGRHLATFKYALELTPLFISHMYNYKTNKNWQDRTASAT--GLKARVDNFTIDLHQRS 1590
Query: 1685 EIFHEYKKQLQVTKRR---ASLKFFEAXXXXXXXXXXXXFASFSKAEYAKTHSPDICIFD 1741
E HE K + + ++ S+K A ASF + + S + D
Sbjct: 1591 EK-HEVKNKANLGRKHQEATSMKVHLAEIDFKTIDLRAISASFDEGALDNSDSIPANVLD 1649
Query: 1742 ED-------------MTWFDVDDFTEFNISNPGTLIPTVVVKPLLFSPMFAYKKIAPYGD 1788
E+ W D+DD+ E + P + PL FSP F Y +
Sbjct: 1650 EEEKECFSFKNVDGPANWVDIDDYHEADWLLPQQN-EKCSIYPLAFSPRFTYYRHTKCHR 1708
Query: 1789 KYQVDFETFEPIE-PFNNARYHDCNL---RKYVAIPDHLINDRHRIFAEEKSKLEEKVND 1844
+ + + + P F + H C + A+ L+ R + E S +E++
Sbjct: 1709 RNEKNEKEIIPDTCRFGDEFTHRCLMPSRENPKAVQYELLQKRRKELEEFMSSEQERIGF 1768
Query: 1845 GNC---TDNEKIELQERLEMIEKTIAQLELMKTDINFLNSEYERADRESDVPDTSAEKLN 1901
++N+ E+++ E + K I L + +L + + S + +++
Sbjct: 1769 LKSQLESNNDSEEVRQEYEELTKRIVTLSDHYRLLEYLLKDESSCSQASQCSENG--QVD 1826
Query: 1902 LPILNFMKSSHNSNKNYANKFIVVSMLLKWNEEVRNVFLKYMHRVSLLSDMNSVTKLKTL 1961
L + +S H N N+F+ ++ +KWN +RN + Y+H V + K +
Sbjct: 1827 LSYASLSESVHAFN----NRFVAHNVQVKWNNFIRNAVMSYVHEVERVRGFAYYMSQKAI 1882
Query: 1962 QTLDSLINKNRQSINTIAXXXXXXXXXXXXXXXQVFKSIFHEDK--------EPEEIVSS 2013
L L K +S N + K + + K + + S
Sbjct: 1883 VFLRDL-EKRTESANDDFFGNYTEDDEDRENARHLLKFLLEDSKKRFWVKTSDADREHGS 1941
Query: 2014 FQNDIKMLAGDFDYKTFEKHHVQLIAPQIQLTTITDPDACILVTAPTIKINSLCF-DSNT 2072
+ + ++ + +Y + + + I+PQIQL ++P+ ++++ +++I L D
Sbjct: 1942 EEGNTNSISNN-EYDIIQSYVFRFISPQIQLQCSSNPEKAVIISIQSLQIKILSVVDPIF 2000
Query: 2073 SGNEYQQNLFMRRTGVLLTNSNVFVFHKK---EQGSYGHLLFDNFLYGSTLETSWRPWLG 2129
N+ N + R + N + F KK E + L+ + YG T W PW+
Sbjct: 2001 PDNDI--NYLIERRFLCKVNESQFFISKKSDFEVVNASSLVLNE--YGCEHNTVWPPWVP 2056
Query: 2130 LELCFN----PENLTENMLISNFTSVFTYDQVLPFANIPDSLK----DSNVLNNRISCDF 2181
E F+ P + + +F+ ++T L S + D + + ++ DF
Sbjct: 2057 FETTFDFVLTPAAFSRFLHRVSFSVIYTKHNDLRLQETVHSTRAFFEDLDTHADTLTFDF 2116
Query: 2182 PRIVIESNSARYISLFNLVTNLLLYVEPESAKMKDDIKKLVLSFNFEDLSIVKEMISVLE 2241
PR+V ++S++Y +F ++T+LLLY EP + +++++L+ +F DL+ E++ L+
Sbjct: 2117 PRVVFSTDSSQYYDIFTIITDLLLYKEPAQKQRNQRLEEIMLAADFSDLTGTSEVVRALQ 2176
Query: 2242 KEIDALNTLENEYS-YRKYLLDDAEISD---LNNIRYNKFDSIMKTHMIMKVLTSASPEQ 2297
+ L L+ ++ Y A I+ L N + + + + + + Q
Sbjct: 2177 ARVHRLLDLKLQHQLYDVTFGIYAHIAQQLFLQNELHRCGEELYYLIESIAAVQNRGIHQ 2236
Query: 2298 SNDEEMLLIVLKAKEIILHMLDDDGDNFLDVAVADMAFQRMETSSGYNFNRMTVGIGQVI 2357
+ L L AKE++ H+L+D+ FLDV + + F+R+E S NFN + + +
Sbjct: 2237 NKVRSNLSWFLMAKEVVWHLLEDNKKPFLDVRLQNATFRRIENSDASNFNTLEIEFMKGS 2296
Query: 2358 NLSHDALFHDLLSP-VEKELTES---SEPFIDLQWEKNKAVGGIQVVKNVVTNLQTLKLN 2413
NL+ F +++ P E + + FI + WE +AV GIQV+++ NL L L
Sbjct: 2297 NLAPGCQFENIICPYFNHEFSNEQLLQQKFIRIHWEVLEAVAGIQVIQHFEINLFPLSLQ 2356
Query: 2414 VEQSTIEKIIAWVSPSSVSLLIXXXXXXXXXXXXXXXLQXXXXXXXXXXXXXXANGIQSQ 2473
+EQ K+ A+ P+ Q
Sbjct: 2357 IEQELATKLFAYAFPNRNESDGFPHIYSRNHDKRKENGSQGEADNSNYSGSLMRRRTNDQ 2416
Query: 2474 QYSIMQSPTE------------LIFPVDDMLGND----MEMEEMIQRSKDNMIIENIKIN 2517
+ + +P+ + F +D L D ME++ M+ R+ NM+I KI
Sbjct: 2417 EEDALATPSSSRRDSRSKRASLIDFTIDKCLDVDDEGRMELQSMLDRAGSNMLITYFKIP 2476
Query: 2518 SFLMIISYQGTGAKRLINVTDFNLNFPLIRFTNQTMTMLDLMMHLKKVLIKSLLRHTGKF 2577
S ++ +SY+GTG L N+T F P + + N+ + LDL M LK LI++++ HTGK
Sbjct: 2477 SVVLRLSYRGTGGLGLENITGFVFTVPTMEYRNEVCSYLDLAMKLKHDLIRTVVSHTGKL 2536
Query: 2578 IGNKLKKHRSVKRLRGAARSPLKQL 2602
+ K+K + +K S L L
Sbjct: 2537 LVEKVKGNYHLKEHEREVSSELLNL 2561
>YPR117w [S] KOG1910 Uncharacterized conserved protein
Length = 2489
Score = 436 bits (1122), Expect = e-121
Identities = 396/1718 (23%), Positives = 725/1718 (42%), Gaps = 261/1718 (15%)
Query: 981 HRFEMYKLFDNISTTFKSIKQMLHSLASESNESVIYPKVTKFIAIPKIKVKSSRWIFSVE 1040
+ F Y + DNI T +KS KQ+ + ++ + +YP+ +P + + ++ +E
Sbjct: 845 YHFRFYMITDNIVTLYKSFKQIKLAFSNLNEFKRLYPQQQFPKKVPNLHICCQDFLIDIE 904
Query: 1041 DDPFESELNLLLQIGLREQKERLEKYNIFRKRV----EMELKKPQVKNLRKSASFTSKNT 1096
+DPFE EL L+L++G+ EQ+ERL+K F++++ +M ++ + + + SF
Sbjct: 905 EDPFEQELGLILKVGVLEQRERLKKLEEFKEKLSTYEDMNVRLRSLYDTSRGQSFFP--- 961
Query: 1097 VPXXXXXXXXXXXXXXMIGFDSYDFDGADGMTEQLKEEYERLTRHISKSWITRVKKQRNL 1156
+F D EQ + Y RL + S SWI R +K +
Sbjct: 962 -----------------------EFYANDQEYEQ--KAYLRLLENFSTSWIARYRKAKLS 996
Query: 1157 LKNHFSENFEFLWGKLDITKLPKDFNKNVLDFTSSPALMNLIFEDIDIDLSKPSFGVENI 1216
+ + + +L ++ TS+ A NL+ +D+D L PSF ++N
Sbjct: 997 F-------YGMPYRVISREELGTKYHLFTRQKTSTVA--NLVVKDLDFKLGSPSFPLDNY 1047
Query: 1217 PDFIHDVGKKVPKDTKYSIMIPLNLNANFSEIRCHLKDYPLPAVHFPKENADTKKPTTNL 1276
DF++ GKKVPK T+Y+++I L L + L+DYP+PA+ FP
Sbjct: 1048 MDFVYQYGKKVPKSTEYTLLIILGLKIKSALWELRLRDYPIPAISFP------------- 1094
Query: 1277 KCDLLITEDMIHSDK-----ELRTIYVPLVPSAH---LEDSESLYSLLIPRTLTAIKLFT 1328
D T D++ ++K L T+YVP V SA D+ ++Y L I RT+ ++K +
Sbjct: 1095 --DTFTTGDVVFAEKMPAPCALHTVYVPFVSSAQRSPYNDANTIYGLHIIRTINSVKTYF 1152
Query: 1329 DIQLDITSSDNVRFVWGGSYSGAIQQTMKCFDNFSKPPIDPSPAVGFWDKIRNIFHARIS 1388
+I+ +TSS + R WG S + M FD +KP IDPS +GFWDK R + H +
Sbjct: 1153 NIRSMVTSSSSARITWGKSLQPGYESLMLWFDFLTKPLIDPSKKLGFWDKFRYLVHGKWI 1212
Query: 1389 INLPN-SCFEVALKGDKNPYKIGGMSAGYALIFKDNVKIFCNKNDNPQKFLTVTASELSF 1447
S + +KG +PYKI AG A + I+ + + +P++FL + +
Sbjct: 1213 YEFSEESEIHLNIKGSHDPYKITDDGAGLAFCWSGGTTIYVHNSTDPKEFLKIESQRFQL 1272
Query: 1448 SIPNFFAKPLPVWNVPSEQSLFFPVEEFSNLQENAAFYYLLESAKMPKDKKDIEIMSKAY 1507
++P+F AK+ K
Sbjct: 1273 AVPDF--------------------------------------AKVSK------------ 1282
Query: 1508 IEKTAIMLTGGMQFNVGIMFER---QNKETNKRTFELKPHYEFRLCNPIYVPKSEDHDSY 1564
+K + L G + + +G++FE+ +R +PHYE +L NP V + HD+Y
Sbjct: 1283 FDKVFMKLDGRVIWTLGLLFEQGDISKAGDEERFLPNRPHYEIQLMNPDGVADLDHHDTY 1342
Query: 1565 AGFRSDFIHLSFDLISKSEDAYNCMQLTPNAFKIFFKWWSTF----SGNLPVRKGPLFSD 1620
GFR+ FIH+SF + S + N + L P A FFKWW+ F SG P+R+G LF+D
Sbjct: 1343 KGFRTSFIHMSFGVYSSEHGSINSLYLAPYALTHFFKWWNLFHTYTSG--PIRQGRLFTD 1400
Query: 1621 E-RFSPKFGTHLYTISYRADVYPLFICHMVPGLDPKALVDSSVNAEVFGLKAKMSEFSMD 1679
+ KFG L+TI+Y+ + L + H+ + + ++ GLK + +D
Sbjct: 1401 VLQNKTKFGRSLFTIAYQLHLKRLMVTHIYRHITTQYDLEKDRKITFTGLKGRFDSLKID 1460
Query: 1680 LHQRKEIFHEYKKQLQVTKRRASLKFFEAXXXXXXXXXXXXFASFSKA------------ 1727
LHQ++ ++L +K K F +
Sbjct: 1461 LHQKRVKLTHTNQKLNKSKPVWKFKMSRGEIDCAEADIRILSTLFDQEAVKEILTSGLDG 1520
Query: 1728 ----EYAKTHSPDICIFDEDMTWFDVDDFTEFNISNPGTLIPTVVVK-PLLFSPMFAYKK 1782
E ++ +P + + W+D +D+ + N G+ +P + PLL+SP +Y +
Sbjct: 1521 ILEDEPSRPITPQDVEYLRESDWYDYEDYIDLNQVPLGSSLPLKLEAIPLLYSPRISYFR 1580
Query: 1783 IAPYGDKYQVDFETFEPIEPFNNARYHDCNLRKY--VAIPDHLINDRHRIFAEEK----- 1835
+++ + + PF H+C + K + L +R R E+
Sbjct: 1581 --------KINDDGYVLAYPFGTEESHNCLIGKNHPELTQEKLATERKREIEEQLKLLHI 1632
Query: 1836 --SKLEEKVNDGNCTDN----------EKIELQERLEMIEKTIAQLELMKTDINFLNSEY 1883
S+L+ G+ + N E EL RL + ++ L++ +T +
Sbjct: 1633 TLSELQSNKGGGSVSGNSERYARELKAEVAELNHRLHTVNTILSDLKISET----IPGGN 1688
Query: 1884 ERADRESDVPDTSAEKLNLPILNFMKSSHNSN-----------------KNYANKFIVVS 1926
D S + DT N P + S +N Y N+F+V +
Sbjct: 1689 TDGDSSSSLSDTDVNLENAPPIQNRISLLRTNTVESFVSMRKASTMQVESTYDNRFMVHN 1748
Query: 1927 MLLKWNEEVRNVFLKYMHRVSLLSDMNSVTKLKTLQTLDSLINKNRQSINTIAXXXXXXX 1986
+ LK + ++R+ L+Y M K++ L L+ + T
Sbjct: 1749 IELKIDNKIRHHLLEYASSAFERKSMRFAVTYKSVTILKELLGNVLTGVRT--------- 1799
Query: 1987 XXXXXXXXQVFKSIFHED-KEPEEIVSSFQNDIKML-AGDFDYKTFEKHHVQLIAPQIQL 2044
+ + SI +D E + F+ I+ + + DFDY + + +LI+PQ+Q+
Sbjct: 1800 ------SVEDYGSILEDDLASNSEFIEHFEKLIREVPSDDFDY--VDNYLFRLISPQVQI 1851
Query: 2045 TTITDPDACILVTAPTIKINSLCFDS--NTSGNEYQ---QNLFMRRTGVLLTNSNVFVFH 2099
+ + +A +++ A I++ + SG + R + + +F
Sbjct: 1852 KSDVERNAAVILAARDIEMGIIDIVQVYGKSGKRIPVDVDTIVETRYSAVSKDIQLFTLF 1911
Query: 2100 KKE-QGSYGHLLFDNFLYGSTLETS-WRPWLGLELCFNPENLTENMLISNFTSVFTYDQV 2157
KK+ +G G N YGS E+ W PW+ LE+CF+ L +++ + + TY
Sbjct: 1912 KKDLEGPEGRFFHKNG-YGSDKESDIWPPWIPLEMCFDGSLLDKHVFLKRRSMFLTYVAP 1970
Query: 2158 LP-FANIPDSLKDSNVLNNRISCDFPRIVIESNSARYISLFNLVTNLLLYVEPESAKMKD 2216
P F + D+ S ++R FP +V+ S+ +Y +++ + +LL + + + +
Sbjct: 1971 NPLFFSANDTSAFS--YDSRFRIAFPGLVLTSDCQQYCAVYAIAEDLLSF----GSSLDE 2024
Query: 2217 DIKKLV-------LSFNFEDLSIVKEMISVLEKEIDALNTLENEYSYRKYLLDDAEISDL 2269
++KL + N E+L + +++ L++ I L Y R YL +
Sbjct: 2025 KVEKLSRILFTDEVRNNLENLDV--SVVTALQERIKEL------YYTRAYLKLHEPRLFM 2076
Query: 2270 NNIRYNKFD---SIMKTHMIMKVLTSASPEQSNDEEMLLIVLK----AKEIILHMLDDDG 2322
+ + FD S +K ++M + + ++ L+ E+I + D+
Sbjct: 2077 KSGQELTFDIQTSTLKLTLLMTAIKKTYDRMGSGNRVIQKRLRWQVGTDELIWELYDESK 2136
Query: 2323 DNFLDVAVADMAFQRMETSSGYNFNRMTVGIGQVINLSHDALFHDLLSP-VEKELTESSE 2381
F+ + + F R ETS G N N++++ Q N + ++ +LL+P E +
Sbjct: 2137 TPFVTIGLGPSTFIRSETSDGTNSNKVSISSLQCFNQQENPVYTELLAPFYENSSYNKNA 2196
Query: 2382 PFIDLQWEKNKAVGGIQVVKNVVTNLQTLKLNVEQSTIEKIIAWVSPSSVSLLIXXXX-- 2439
P +++ W +VGGI +++++ +LQ L ++ T EK++ ++ P I
Sbjct: 2197 PMVEIFWILGPSVGGISDLQDLIVSLQPLIFKMDHKTSEKLMNYLFPKIEQTSIEPNSPE 2256
Query: 2440 ---XXXXXXXXXXXLQXXXXXXXXXXXXXXANGIQSQQYSIMQSPTELIFPVDD------ 2490
A + S +QS + D
Sbjct: 2257 LVPRSSTSSFFSSSPVLRHSLSNGSLSVYDAKDVDSWDLRSIQSKEGIKKHKGDHRKLSA 2316
Query: 2491 --MLGNDMEMEEMIQRSKDNMIIENIKINSFLMIISYQGTGAKRLINVTDFNLNFPLIRF 2548
+ D + EM++RS +++I I LM + Y+G+ + L +V + + P++++
Sbjct: 2317 SLFVQPDYNINEMVKRSGTFFNVKSIIIRKTLMSVCYKGSHS-LLTDVNNLIVRVPVLKY 2375
Query: 2549 TNQTMTMLDLMMHLKKVLIKSLLRHTGKFIGNKLKKHR 2586
N+ + + LK+ +++ +L+H G IGNK H+
Sbjct: 2376 HNKLWSREEFFTALKRDVVRIVLQHLGNIIGNKFLPHK 2413
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150,514,520
Number of Sequences: 60738
Number of extensions: 6619206
Number of successful extensions: 17895
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 17835
Number of HSP's gapped (non-prelim): 16
length of query: 2629
length of database: 30,389,216
effective HSP length: 124
effective length of query: 2505
effective length of database: 22,857,704
effective search space: 57258548520
effective search space used: 57258548520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)