ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2838 good YU KOG3091 Intracellular trafficking, secretion, and vesicular transport Nuclear pore complex, p54 component (sc Nup57)
r_klactII2838 good YU KOG3091 Nuclear structure Nuclear pore complex, p54 component (sc Nup57)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2838 977257 978969 571
(571 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR119c [YU] KOG3091 Nuclear pore complex p54 component (sc Nup57) 298 1e-80
SPBC19G7.15 [YU] KOG3091 Nuclear pore complex p54 component (sc ... 128 3e-29
YMR047c [YU] KOG0845 Nuclear pore complex Nup98 component (sc Nu... 57 1e-07
Hs22041284 [YU] KOG3091 Nuclear pore complex p54 component (sc N... 52 2e-06
CE10988_1 [YU] KOG0845 Nuclear pore complex Nup98 component (sc ... 52 2e-06
>YGR119c [YU] KOG3091 Nuclear pore complex p54 component (sc Nup57)
Length = 541
Score = 298 bits (764), Expect = 1e-80
Identities = 195/506 (38%), Positives = 243/506 (47%), Gaps = 37/506 (7%)
Query: 70 FGSTQQQQKPSTGGLFXXXXXXXXXXXXLFGQSXXXXXXXXGLFGNANSTGIQQNNTAPT 129
FGS QQ STGG + GLFG + Q +
Sbjct: 65 FGSNQQS---STGGGLFGNKPALGSLGSSSTTASGTTATGTGLFGQQTA----QPQQSTI 117
Query: 130 SGGLFGSKPA---GGLFNNTQQSTTGIQGNPTGGGLFXXXXXXXXXXXXXXXXXXXXXXX 186
GGLFG+KP GGLF N+ Q+ + T GGLF
Sbjct: 118 GGGLFGNKPTTTTGGLFGNSAQNNS-----TTSGGLFGNKVGSTGSLMGGNSTQNTSNMN 172
Query: 187 ATSGGLFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPVAPATTS-LFXXXXXXXXXXX 245
A GGLF KP T LF
Sbjct: 173 A--GGLFGAKPQNTTATTGGLFGS-------------KPQGSTTNGGLFGSGTQNNNTLG 217
Query: 246 XXXXXXXXX---XXXASLFGSTPSTTMQPSFAWSNTXXXXXXXXXXXXXXXXXXXXXXXX 302
A G+T ST QPSFAWS
Sbjct: 218 GGGLFGQSQQPQTNTAPGLGNTVST--QPSFAWSKPSTGSNLQQQQQQQIQVPLQQTQAI 275
Query: 303 XXXXXXXXXXXXXXXXXILKCKESWVPSEQRSKLKTFVYNKCTETEAMLYNKPLSISQDD 362
+LKCKESW P+ ++KL+ FVYNK ETEA+LY KP + Q++
Sbjct: 276 AQQQQLSNYPQQIQEQ-VLKCKESWDPNTTKTKLRAFVYNKVNETEAILYTKPGHVLQEE 334
Query: 363 WDQALMSKPGNNTIPIRLLGFQDLNDRNQLQKQHVAQARVLLGQILEKLNQVNTKHDLDT 422
WDQA+ KP TIPI++ GF+ LN RNQ+Q ++VAQAR++L ILEK Q+ KH+LDT
Sbjct: 335 WDQAMEKKPSPQTIPIQIYGFEGLNQRNQVQTENVAQARIILNHILEKSTQLQQKHELDT 394
Query: 423 QSRIAKAVSRNTVIENRILKLASQLAILKSKNLPLSLHEEEMMNKFNKLLQESNDPAGLG 482
SRI KA SRN IE RILKL +QLA LK++ LPL + EE+M ++F LLQ S DPAGLG
Sbjct: 395 ASRILKAQSRNVEIEKRILKLGTQLATLKNRGLPLGIAEEKMWSQFQTLLQRSEDPAGLG 454
Query: 483 KNNELWARLSVLKERAKNISEQLDSTLVVISEXXXXXXXXXXXQDEELEDRVNKIAEILS 542
K NELWARL++LKERAKNIS QLDS L+V ++ EE DR+NKI EIL+
Sbjct: 455 KTNELWARLAILKERAKNISSQLDSKLMVFNDDTKNQDSMSKGTGEESNDRINKIVEILT 514
Query: 543 NQQRGLCFLNDVIEKDQKLVDEVHTK 568
NQQRG+ +LN+V+EKD +V + K
Sbjct: 515 NQQRGITYLNEVLEKDAAIVKKYKNK 540
>SPBC19G7.15 [YU] KOG3091 Nuclear pore complex p54 component (sc Nup57)
Length = 403
Score = 128 bits (321), Expect = 3e-29
Identities = 69/239 (28%), Positives = 128/239 (52%), Gaps = 12/239 (5%)
Query: 320 ILKCKESWVPSEQRSKLKTFVYNKCTETEAMLYNKPLSISQDDWDQALMSKPGNNTIPIR 379
+ K +W + + F YNK +A LY KP + +Q WD+A+ ++P N+ +P+
Sbjct: 160 VQKILNAWNLNHPDCAFQRFFYNKVPVEQAALYVKPPNYNQQKWDEAVANRPSNSVVPVL 219
Query: 380 LLGFQDLNDRNQLQKQHVAQARVLLGQILEKLNQVNTKHDLDTQSRIAKAVSRNTVIENR 439
+GF D+ R +Q Q V R+ + +I+E L +++ KHDLD ++A+A +R+ + R
Sbjct: 220 AVGFPDVQKRINMQIQQVNTYRIRMREIVETLGRLSNKHDLDFSIKLAEAKNRHVRLSER 279
Query: 440 ILKLASQLAILKSKNLPLSLHEEEMMNKFNKLLQESNDPAGLGKNNELWARLSVLKERAK 499
IL+LA ++ +L+ + L +EEE+ K + L + N+P G+ NE+WAR++++ E K
Sbjct: 280 ILRLAIKVHVLRHRGYALKPNEEELRKKLDDLTKSLNNPEIFGRLNEIWARITLIFEGEK 339
Query: 500 NISEQLDSTLVVISEXXXXXXXXXXXQDEELEDRVNKIAEILSNQQRGLCFLNDVIEKD 558
ISE + D++ I ++L + Q GL ++ ++++D
Sbjct: 340 ------------ISEDQRSNLAKGVVDWRKNSDQLEVITDVLRDHQVGLSYVVKLMQED 386
>YMR047c [YU] KOG0845 Nuclear pore complex Nup98 component (sc
Nup145/Nup100/Nup116)
Length = 1113
Score = 56.6 bits (135), Expect = 1e-07
Identities = 40/95 (42%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 69 LFGSTQQQQKPSTGGLFXXXXXXXXXXXXLFGQSXXXXXXXXGLFGNANSTGIQQNNTAP 128
LFG T QQQ S GGLF LFGQ+ GLFG NS+
Sbjct: 383 LFGQTNQQQ--SGGGLFGQQQNSNAGG--LFGQNNQSQNQS-GLFGQQNSSNAF--GQPQ 435
Query: 129 TSGGLFGSKPAGGLFNNTQQSTTGIQGNPTGGGLF 163
GGLFGSKPAGGLF Q ++T GN +F
Sbjct: 436 QQGGLFGSKPAGGLFGQQQGASTFASGNAQNNSIF 470
Score = 51.6 bits (122), Expect = 3e-06
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 22/94 (23%)
Query: 71 GSTQQQQKPSTGGLFXXXXXXXXXXXXLFGQSXXXXXXXXGLFGNANSTGIQQNNTAPTS 130
G Q +Q+P++GGLF S GLFGN QNN A TS
Sbjct: 560 GLFQNKQQPASGGLFG---------------SKPSNTVGGGLFGNNQVAN--QNNPASTS 602
Query: 131 GGLFGSKPA-GGLFNNTQQSTTGIQGNPTGGGLF 163
GGLFGSKPA G LF T + N + GG+F
Sbjct: 603 GGLFGSKPATGSLFGGTNSTAP----NASSGGIF 632
>Hs22041284 [YU] KOG3091 Nuclear pore complex p54 component (sc Nup57)
Length = 327
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/231 (21%), Positives = 103/231 (43%), Gaps = 30/231 (12%)
Query: 346 ETEAMLYNKPLSISQDDWDQALMSKPGNNT-IPIRLLGFQDLNDRNQLQKQHVAQARVLL 404
+ + +L N P + W+QA + P + IP+ ++GF++L R ++Q Q Q + L
Sbjct: 112 QIKQLLQNPPAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRL 171
Query: 405 GQILEKLNQVNTKHDLDTQSRIAKAVSRNTVIENRILKLASQLAILKSKNLPLSLHEEEM 464
I E ++++ K+ + ++IA+ + + +R L++ + I + + EE++
Sbjct: 172 DIISEDISELQ-KNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQL 230
Query: 465 MNKFNKLLQESNDPAGL-GKNNELWARLSVLKERAKNISEQ---LDSTLVVISEXXXXXX 520
+ + + E N P G+ NEL +++ + SE+ +D+
Sbjct: 231 RVQLDTIQGELNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDA------------- 277
Query: 521 XXXXXQDEELEDRVNKIAEILSNQQRGLCFLNDVIEKDQKLVDEVHTKLNK 571
D + +I + L QQ GL L +I+ D + + V LN+
Sbjct: 278 -----------DLLREIKQHLKQQQEGLSHLISIIKDDLEDIKLVEHGLNE 317
>CE10988_1 [YU] KOG0845 Nuclear pore complex Nup98 component (sc
Nup145/Nup100/Nup116)
Length = 608
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/216 (25%), Positives = 63/216 (28%), Gaps = 30/216 (13%)
Query: 69 LFGSTQQQQKPSTGGLFXXXXXXXXX-XXXLFGQSXXXXXXX----XGLFG------NAN 117
LFGST P GGLF LFG S GLFG NA
Sbjct: 170 LFGSTAAPAAP--GGLFGSTSTSTAAPSGGLFGSSAAPTSTAPAPSGGLFGAAPATSNAA 227
Query: 118 STGIQQNNTAP----TSGGLFGSKP-----AGGLFNNTQQSTTGIQGNPTGGGLFXXXXX 168
T N+AP +SGGLFG+ P +GGLF +T +TT T G
Sbjct: 228 PTSGLFGNSAPAATASSGGLFGAAPKPAAPSGGLFGSTAPATTAATTTATSGLFGAPTSA 287
Query: 169 XXXXXXXXXXXXXXXXXXATSGGLFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPVAP 228
A +GGLF P A
Sbjct: 288 PSSAPATGGLFGASTAPAAATGGLFSIGAASASTPSVGLFGNSSASTTAAAAPATAPAAA 347
Query: 229 ATTSLFXXXXXXXXXXXXXXXXXXXXXXXASLFGST 264
+T LF LFGST
Sbjct: 348 STGGLF--------GATTAAAAAPTSSTTGGLFGST 375
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.313 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,730,756
Number of Sequences: 60738
Number of extensions: 721685
Number of successful extensions: 1984
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1937
Number of HSP's gapped (non-prelim): 23
length of query: 571
length of database: 30,389,216
effective HSP length: 112
effective length of query: 459
effective length of database: 23,586,560
effective search space: 10826231040
effective search space used: 10826231040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)