ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2854 good R KOG3234 General function prediction only Acetyltransferase, (GNAT) family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2854 985951 986541 197
(197 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR131c [R] KOG3234 Acetyltransferase (GNAT) family 244 7e-65
SPCC16C4.12 [R] KOG3234 Acetyltransferase (GNAT) family 135 4e-32
7293615 [R] KOG3234 Acetyltransferase (GNAT) family 115 4e-26
CE25639 [R] KOG3234 Acetyltransferase (GNAT) family 110 9e-25
At1g03150 [R] KOG3234 Acetyltransferase (GNAT) family 108 4e-24
Hs7705823 [R] KOG3234 Acetyltransferase (GNAT) family 108 5e-24
ECU07g1680 [R] KOG3234 Acetyltransferase (GNAT) family 77 1e-14
At5g13780 [R] KOG3235 Subunit of the major N alpha-acetyltransfe... 62 4e-10
CE18023 [R] KOG3235 Subunit of the major N alpha-acetyltransferase 61 9e-10
Hs14249280 [R] KOG3235 Subunit of the major N alpha-acetyltransf... 56 3e-08
SPAC15E1.08 [R] KOG3235 Subunit of the major N alpha-acetyltrans... 56 4e-08
7298032_2 [R] KOG3234 Acetyltransferase (GNAT) family 55 5e-08
Hs10835057 [R] KOG3235 Subunit of the major N alpha-acetyltransf... 54 2e-07
7294847 [R] KOG3235 Subunit of the major N alpha-acetyltransferase 52 7e-07
>YPR131c [R] KOG3234 Acetyltransferase (GNAT) family
Length = 251
Score = 244 bits (622), Expect = 7e-65
Identities = 119/197 (60%), Positives = 139/197 (70%), Gaps = 2/197 (1%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYE 60
MT++QPFE D F N VNLD TENFP+EFY EY+I+WP L FKS EMT + + ++
Sbjct: 57 MTTIQPFEPVDLFKTNNVNLDILTENFPLEFYFEYMIIWPDLFFKSSEMT--VDPTFKHN 114
Query: 61 ISGYMMGKTEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDLFV 120
ISGYMM KTEGK +WH HITAVT++PRFRRISLAS LC+TL+T+TD PH VNFIDLFV
Sbjct: 115 ISGYMMAKTEGKTTEWHTHITAVTVAPRFRRISLASKLCNTLETMTDVMPHEVNFIDLFV 174
Query: 121 KCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLKDAFDMRHGMERDQGKS 180
KCNNQLAI LYEKL NS D P K +D KDAFDMR M RD+ +S
Sbjct: 175 KCNNQLAIKLYEKLGYSVYRRVVGYYNSAEDGYPDTLKKVDDNKDAFDMRKAMARDRNRS 234
Query: 181 LRADGRKHNCLPMDIRF 197
+R DGR H C P D+RF
Sbjct: 235 VRPDGRSHKCYPHDVRF 251
>SPCC16C4.12 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 180
Score = 135 bits (340), Expect = 4e-32
Identities = 76/199 (38%), Positives = 109/199 (54%), Gaps = 21/199 (10%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSL-MFKSIEMTSPLHGSEEY 59
MT + F+ATD FS N +NLD TE F I FYL YL WPSL + + +++ P
Sbjct: 1 MTDTRKFKATDLFSFNNINLDPLTETFNISFYLSYLNKWPSLCVVQESDLSDPT------ 54
Query: 60 EISGYMMGKTEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDLF 119
+ GY+MGK+EG G++WH H+TA+T++P RR+ LA + D L+T+ + N F+DLF
Sbjct: 55 -LMGYIMGKSEGTGKEWHTHVTAITVAPNSRRLGLARTMMDYLETV--GNSENAFFVDLF 111
Query: 120 VKCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLKDAFDMRHGMERDQGK 179
V+ +N LAI Y+ L I S +D+FDMR + RD +
Sbjct: 112 VRASNALAIDFYKGLGYSVYRRV----------IGYYSNPHGKDEDSFDMRKPLSRDVNR 161
Query: 180 -SLRADGRKHNCLPMDIRF 197
S+R +G C P D+ F
Sbjct: 162 ESIRENGENFKCSPADVSF 180
>7293615 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 175
Score = 115 bits (288), Expect = 4e-26
Identities = 63/179 (35%), Positives = 92/179 (51%), Gaps = 22/179 (12%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYE 60
MT+++PF D F N VN D TE + + FY +YL WP L S +
Sbjct: 1 MTTLRPFTCDDLFKFNNVNFDPLTETYGLSFYTQYLAKWPEYF--------QLAESPSGQ 52
Query: 61 ISGYMMGKTEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDLFV 120
I GY+MGK EG +WH H+TA+T+SP +RR+ LA++L L+ I++ F+DLFV
Sbjct: 53 IMGYIMGKVEGHLDNWHGHVTALTVSPDYRRLGLAALLMSFLEDISEKK--RAYFVDLFV 110
Query: 121 KCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLKDAFDMRHGMERDQGK 179
+ +NQ+AI++Y L + D +DA+DMR + RD K
Sbjct: 111 RKSNQVAINMYTNLGYIIYRTILEYYSGDQD------------EDAYDMRKALSRDVNK 157
>CE25639 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 173
Score = 110 bits (276), Expect = 9e-25
Identities = 61/179 (34%), Positives = 96/179 (53%), Gaps = 22/179 (12%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYE 60
MT+++PF+ D F N VNLD TE + +FYL Y++ +P ++ +G E
Sbjct: 1 MTTLRPFDVMDMFKFNNVNLDINTETYGFQFYLHYMMNYPEYY----QVAEHPNG----E 52
Query: 61 ISGYMMGKTEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDLFV 120
I Y+MGK EG+ +WH H+TA++++P FRR+ LA+ + + L+ ++ F+DLFV
Sbjct: 53 IMAYVMGKIEGRDTNWHGHVTALSVAPNFRRLGLAAYMMEFLERTSE--ARRAYFVDLFV 110
Query: 121 KCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLKDAFDMRHGMERDQGK 179
+ +N++AI LY+KL D +DAFDMR + RD K
Sbjct: 111 RVSNKIAIELYKKLGYVVYRQIIGYYTGDRD------------EDAFDMRKSLSRDPEK 157
>At1g03150 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 174
Score = 108 bits (271), Expect = 4e-24
Identities = 59/166 (35%), Positives = 85/166 (50%), Gaps = 13/166 (7%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEE-- 58
MT+++ F D +VNLD TE F + FY+ YL WP H +E
Sbjct: 1 MTTIRRFSCNDLLRFTSVNLDHLTETFNMSFYMTYLARWPDYF----------HVAEGPG 50
Query: 59 YEISGYMMGKTEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDL 118
+ GY+MGK EG+G+ WH H+TAVT+SP +RR LA L + L+ I+D F+DL
Sbjct: 51 NRVMGYIMGKVEGQGESWHGHVTAVTVSPEYRRQQLAKKLMNLLEDISDKI-DKAYFVDL 109
Query: 119 FVKCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLK 164
FV+ +N AI +YEKL + + D + R D++
Sbjct: 110 FVRASNTPAIKMYEKLGYIIYRRVLRYYSGEEDGLDMRKALSRDVE 155
>Hs7705823 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 178
Score = 108 bits (270), Expect = 5e-24
Identities = 61/181 (33%), Positives = 101/181 (55%), Gaps = 21/181 (11%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYE 60
MT+++ F D F N +NLD TE + I FYL+YL WP + + G E
Sbjct: 1 MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYF-----IVAEAPGG---E 52
Query: 61 ISGYMMGKTEGK--GQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDL 118
+ GY+MGK EG ++WH H+TA++++P FRR+ LA+ L + L+ I++ F+DL
Sbjct: 53 LMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERK--GGFFVDL 110
Query: 119 FVKCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLKDAFDMRHGMERDQG 178
FV+ +NQ+A+++Y++L ++ + +P++ DA+DMR + RD
Sbjct: 111 FVRVSNQVAVNMYKQLGYSVYRTVIEYYSAS-------NGEPDE--DAYDMRKALSRDTE 161
Query: 179 K 179
K
Sbjct: 162 K 162
>ECU07g1680 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 181
Score = 77.4 bits (189), Expect = 1e-14
Identities = 57/192 (29%), Positives = 87/192 (44%), Gaps = 27/192 (14%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYL-------ILWPSLMFKSIEMTSPL 53
M ++P +D SL+ +NLD +E+FP +YL YL I+ PSL+ T
Sbjct: 1 MYKIEPMLPSDILSLDWINLDETSESFPFSYYLYYLINYSEDCIIIPSLLEYETSFT--- 57
Query: 54 HGSEEYEISGYMMGKTEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNV 113
+ +I GYM+GK E K AH +AV+++P +RR M D ++ D +N
Sbjct: 58 ---YKRDIYGYMIGKLEEKDGVISAHASAVSVAPSYRRNRFGKMCMDVMEKSGD--VYNA 112
Query: 114 NFIDLFVKCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLKDAFDMRHGM 173
F DL+V+ N AI Y+KL + ++A DMR +
Sbjct: 113 YFADLYVREGNTTAIEFYKKLGYVTYRKVFNYYVDGAE------------ENALDMRKSL 160
Query: 174 ERDQGKSLRADG 185
+ D+ K A G
Sbjct: 161 KMDKDKVYMARG 172
>At5g13780 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 192
Score = 62.4 bits (150), Expect = 4e-10
Identities = 44/191 (23%), Positives = 84/191 (43%), Gaps = 27/191 (14%)
Query: 1 MTSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEY- 59
M ++ D ++ A NL EN+ +++YL +++ WP L L+ +E+Y
Sbjct: 1 MVCIRRATVDDLLAMQACNLMCLPENYQMKYYLYHILSWPQL----------LYVAEDYN 50
Query: 60 -EISGYMMGKTEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDL 118
I GY++ K E + + H HIT++ + R++ LA+ L + + + ++ L
Sbjct: 51 GRIVGYVLAKMEEESNECHGHITSLAVLRTHRKLGLATKLMTAAQAAME-QVYEAEYVSL 109
Query: 119 FVKCNNQLAISLYEKLXXXXXXXXXXXXNSQTDPIPSRSTKPNDLKDAFDMRHGMERDQG 178
V+ +N+ A +LY + + D +DA+DMR ++ Q
Sbjct: 110 HVRRSNRAAFNLYTETLGYKINDVEAKYYA-------------DGEDAYDMRKNLKGKQN 156
Query: 179 KSLRADGRKHN 189
A G H+
Sbjct: 157 HH-HAHGHHHH 166
>CE18023 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 182
Score = 61.2 bits (147), Expect = 9e-10
Identities = 32/124 (25%), Positives = 66/124 (52%), Gaps = 12/124 (9%)
Query: 11 DFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYEISGYMMGKTE 70
D S+ NL EN+ +++Y + + WP L + + + + GY++ K E
Sbjct: 10 DLMSMQNANLMCLPENYQMKYYFYHALSWPQLSY--------IAEDHKGNVVGYVLAKME 61
Query: 71 -GKGQDWHAHITAVTISPRFRRISLASMLCD-TLKTITDNSPHNVNFIDLFVKCNNQLAI 128
G++ H HIT++ + +RR+ LA+ + D T + + + +N ++ L V+ +N+ A+
Sbjct: 62 EDPGEEPHGHITSLAVKRSYRRLGLANKMMDQTARAMVET--YNAKYVSLHVRVSNRAAL 119
Query: 129 SLYE 132
+LY+
Sbjct: 120 NLYK 123
>Hs14249280 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 229
Score = 56.2 bits (134), Expect = 3e-08
Identities = 35/131 (26%), Positives = 67/131 (50%), Gaps = 12/131 (9%)
Query: 3 SVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYEIS 62
+++ + D ++ NL EN+ +++YL + + WP L + + E+ +I
Sbjct: 2 NIRNAQPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSY--------IAEDEDGKIV 53
Query: 63 GYMMGKTEGKGQDW-HAHITAVTISPRFRRISLASMLCD-TLKTITDNSPHNVNFIDLFV 120
GY++ K E + D H HIT++ + RR+ LA L D + + +N N ++ L V
Sbjct: 54 GYVLAKMEEEPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIEN--FNAKYVSLHV 111
Query: 121 KCNNQLAISLY 131
+ +N+ A+ LY
Sbjct: 112 RKSNRPALHLY 122
>SPAC15E1.08 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 177
Score = 55.8 bits (133), Expect = 4e-08
Identities = 34/131 (25%), Positives = 68/131 (50%), Gaps = 13/131 (9%)
Query: 4 VQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYEISG 63
++P +D + NL EN+ +++YL + I WP L + + T P + + G
Sbjct: 3 IRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVA---TDP-----KGRVVG 54
Query: 64 YMMGKTEGKGQDW--HAHITAVTISPRFRRISLAS-MLCDTLKTITDNSPHNVNFIDLFV 120
Y++ K E + +D H HIT+V++ +R + LA ++ + + + + + ++ L V
Sbjct: 55 YVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVE--VYGAKYMSLHV 112
Query: 121 KCNNQLAISLY 131
+ +N+ AI LY
Sbjct: 113 RKSNRAAIHLY 123
>7298032_2 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 203
Score = 55.5 bits (132), Expect = 5e-08
Identities = 37/143 (25%), Positives = 67/143 (45%), Gaps = 20/143 (13%)
Query: 2 TSVQPFEATDFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYEI 61
TS + F D F N + +D E + + F L ++ P L+ + + + +
Sbjct: 1 TSPRLFVLEDLFKFNNIVMDPLAEVYSLPFLLPKILEHPELVLAA--------DAPDNSL 52
Query: 62 SGYMMGKT---------EGKGQDW-HAHITAVTISPRFRRISLASMLCDTLKTITDNSPH 111
G+++G + K W H HI+A+ ++ +R++ L + L T++ + D
Sbjct: 53 MGFILGTRVEDATESFGDAKTMTWNHGHISALAVAQDYRKLGLGTRLLTTVRDMMDRQKD 112
Query: 112 NVNFIDLFVKCNNQLAISLYEKL 134
+IDLFV+ N +AI LYE L
Sbjct: 113 F--YIDLFVREKNTIAIGLYESL 133
>Hs10835057 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 235
Score = 53.5 bits (127), Expect = 2e-07
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Query: 11 DFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYEISGYMMGKTE 70
D ++ NL EN+ +++Y + + WP L + + E +I GY++ K E
Sbjct: 10 DLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSY--------IAEDENGKIVGYVLAKME 61
Query: 71 GKGQDW-HAHITAVTISPRFRRISLASMLCD-TLKTITDNSPHNVNFIDLFVKCNNQLAI 128
D H HIT++ + RR+ LA L D + + +N N ++ L V+ +N+ A+
Sbjct: 62 EDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIEN--FNAKYVSLHVRKSNRAAL 119
Query: 129 SLY 131
LY
Sbjct: 120 HLY 122
>7294847 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 196
Score = 51.6 bits (122), Expect = 7e-07
Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 12/124 (9%)
Query: 11 DFFSLNAVNLDTFTENFPIEFYLEYLILWPSLMFKSIEMTSPLHGSEEYEISGYMMGK-- 68
D ++ NL EN+ +++Y + + WP L + +++ ++ I GY++ K
Sbjct: 10 DLMTMQHCNLLCLPENYQMKYYFYHGLTWPQLSYVAVD--------DKGAIVGYVLAKME 61
Query: 69 -TEGKGQDWHAHITAVTISPRFRRISLASMLCDTLKTITDNSPHNVNFIDLFVKCNNQLA 127
E + H HIT++ + +RR+ LA L + N ++ L V+ +N+ A
Sbjct: 62 EPEPNEESRHGHITSLAVKRSYRRLGLAQKLMNQASQAMVEC-FNAQYVSLHVRKSNRAA 120
Query: 128 ISLY 131
++LY
Sbjct: 121 LNLY 124
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,966,443
Number of Sequences: 60738
Number of extensions: 409886
Number of successful extensions: 845
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 816
Number of HSP's gapped (non-prelim): 14
length of query: 197
length of database: 30,389,216
effective HSP length: 101
effective length of query: 96
effective length of database: 24,254,678
effective search space: 2328449088
effective search space used: 2328449088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)