ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII2868 good S KOG1043 Function unknown Ca2+-binding transmembrane protein LETM1/MRS7
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII2868 991008 989632 -459
(459 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR125w [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 533 e-151
SPAC23C11.17 [S] KOG1043 Ca2+-binding transmembrane protein LETM... 331 1e-90
YOL027c [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 300 3e-81
At3g59820 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 239 6e-63
Hs6912482 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 238 1e-62
7291797 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 229 8e-60
At1g65540 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 206 8e-53
CE20894 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 204 3e-52
CE11400 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 204 3e-52
Hs21389523 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/... 126 6e-29
Hs20483257 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/... 70 7e-12
At5g06220 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 55 2e-07
At3g11560 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7 54 6e-07
>YPR125w [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 454
Score = 533 bits (1374), Expect = e-151
Identities = 269/400 (67%), Positives = 326/400 (81%), Gaps = 9/400 (2%)
Query: 59 QHQPKPALPVKKEAEPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSR 118
Q PVK++ K+ K++ +HYWDG+KLLGLE+KI+ +L+MK +AGY L+R
Sbjct: 64 QESASKVSPVKEKE--KVPFKVKMQKALRHYWDGSKLLGLEIKISSKLLMKSAAGYPLTR 121
Query: 119 REKIQLKRTTQDMIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESL 178
RE +QLKRTTQD++RLVPF+AF+I+PFAELLLP ALKLFPNLLPSTYES K ++ KLE+L
Sbjct: 122 RENLQLKRTTQDIVRLVPFAAFLIIPFAELLLPFALKLFPNLLPSTYESSKKRENKLENL 181
Query: 179 RKTRSVMSEIIKENKSHFKPSNITEEQKLVFNSFYKHVRETGEPESREQLIQVARLFTDD 238
R TR +MSEIIK NKSHFKP+NI+EEQK +FN FY HVR TG PESR+QLI+VARLFTDD
Sbjct: 182 RNTRKLMSEIIKNNKSHFKPNNISEEQKALFNRFYTHVRATGVPESRQQLIEVARLFTDD 241
Query: 239 TVLDNLTRPYLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYEGVESLDAIEL 298
TVLDN+TRPYL+A+AKY+NLQPFGTDVMLRYRIRYKMLELK DDL+IYYE E L EL
Sbjct: 242 TVLDNVTRPYLIALAKYMNLQPFGTDVMLRYRIRYKMLELKKDDLSIYYEDAEQLSLSEL 301
Query: 299 RTACASRGIRNLNVEESVLRDNLKIWLNMRLKDKIPSTLLVMATAYTYGDIGSKKTLYDA 358
+TACASRGIR+++VE SVL NL++WLNMRLKDKIPSTLL+MATAY YG++ SK++LYDA
Sbjct: 302 KTACASRGIRSVDVEPSVLYSNLRLWLNMRLKDKIPSTLLIMATAYNYGNVQSKESLYDA 361
Query: 359 LCDVLSGIPDELYHEVKVNVVEEDSATNKSKMAQLKEQVEIMKEEEQQEKDAVVRVKDEL 418
LCDVL GIPDELYHEVKVNVV+ED A+ K K+ QL+EQ EIMKEEEQQE++A+V VKDEL
Sbjct: 362 LCDVLIGIPDELYHEVKVNVVKEDEASAKQKLKQLREQEEIMKEEEQQEENAIVSVKDEL 421
Query: 419 SLDAVDAKTVSQTEKAAPQDGEKKPHNARTESESTEATKK 458
SLD D + AAP + KPH+ + E+ +K
Sbjct: 422 SLDDQD----KNIDAAAP---DVKPHDTKPIGEAAAIKEK 454
>SPAC23C11.17 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 485
Score = 331 bits (849), Expect = 1e-90
Identities = 185/412 (44%), Positives = 260/412 (62%), Gaps = 15/412 (3%)
Query: 36 RYYSQETXXXXXXXXXXXXSTALQHQPKPALPVKKEAEPKLSLWAKVKHEAQHYWDGTKL 95
R YS ET A + KP VKK S+W +VK H+WDGTKL
Sbjct: 83 RLYSTETPTPSKVKEAPKQVAA--EETKPTTVVKKP-----SIWQRVKGGVLHFWDGTKL 135
Query: 96 LGLEVKIAMRLVMKMSAGYELSRREKIQLKRTTQDMIRLVPFSAFVIVPFAELLLPIALK 155
LG+E+KI+ +LV KM+ GYEL+RRE QL RT +D+ RLVPFS FV+VPFAELLLPIA+K
Sbjct: 136 LGVEIKISSKLVYKMAVGYELTRRESRQLTRTLKDIGRLVPFSVFVVVPFAELLLPIAVK 195
Query: 156 LFPNLLPSTYESKKDKQTKLESLRKTRSVMSEIIKE--NKSHFKPSNITEEQKLVFNSFY 213
LFPNLLPST+E KDK+ K LRKTR+ +S +++ F SN T E K F F+
Sbjct: 196 LFPNLLPSTFEDAKDKEAKKAQLRKTRNEVSNMLRSTLKSGKFTFSNETRESK-EFRDFF 254
Query: 214 KHVRETGEPESREQLIQVARLFTDDTVLDNLTRPYLVAIAKYINLQPFGTDVMLRYRIRY 273
+ VR +G+ SRE+LI+V + F DD LDNL+R LVA+ +Y+NL FGTD +LRY IR+
Sbjct: 255 QKVRTSGQSPSREELIEVCKYFKDDITLDNLSRAQLVAMCRYMNLNAFGTDPLLRYNIRH 314
Query: 274 KMLELKTDDLAIYYEGVESLDAIELRTACASRGIRNLNVEESVLRDNLKIWLNMRLKDKI 333
+M +++ DD AIY EG+ SL EL AC SRGIR + + L++ L +WL+MR+K I
Sbjct: 315 RMRQIRRDDRAIYIEGINSLSIPELFNACNSRGIRTQGLSPAKLKEELSVWLDMRIKHGI 374
Query: 334 PSTLLVMATAYTYG-DIGSKKTLYDALCDVLSGIPDELYHEVKVNVVEEDSATNKSKMAQ 392
PS +L+++ A++YG + G+ + +DAL D L+ IPDELYHE V++ + +NK ++
Sbjct: 375 PSVILMLSNAFSYGYNEGTYDSRWDALQDTLASIPDELYHETVVDMPTK-QVSNKERLEI 433
Query: 393 LKEQVEIMKEEEQ---QEKDAVVRVKDELSLDAVDAKTVSQTEKAAPQDGEK 441
L+EQ E+++EE + + D + +E + A + E P++ K
Sbjct: 434 LREQEELIEEEAEHVAEHPDLAKKQTEENKATSKPAVSAKSPESNIPKNERK 485
>YOL027c [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 573
Score = 300 bits (768), Expect = 3e-81
Identities = 178/440 (40%), Positives = 257/440 (57%), Gaps = 44/440 (10%)
Query: 63 KPALPVKKEA--EPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRRE 120
KP P +A +PK +L KVKH +HY +GTKLLG E+K++ +L++K + GYELSRRE
Sbjct: 66 KPVAPTSTDAPAKPKETLMVKVKHALKHYANGTKLLGYEIKVSTKLLIKFAQGYELSRRE 125
Query: 121 KIQLKRTTQDMIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLRK 180
+ QL+RT D+ RL+PFSAF+I+PFAEL LP ALKLFPNLLPSTYES KDKQ K L +
Sbjct: 126 RNQLRRTMGDVFRLIPFSAFLIIPFAELFLPFALKLFPNLLPSTYESGKDKQAKRNKLIE 185
Query: 181 TRSVMSEIIKE--NKSHFKPSNITE--EQKLVFNSFYKHVRETGEPE----SREQLIQVA 232
R SE + E +S+ N E E+K F +F++ + E + +++ +A
Sbjct: 186 IRKKTSEFLHETLEESNLITYNTIENAEKKQKFLNFFRKLYSAKEGKIMTFQHDEISAIA 245
Query: 233 RLFTDDTVLDNLTRPYLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYEGVES 292
++F +D+VLDNL+RP L A++K+++L+PFG D MLRY+IR K+ ++ DD I YEGVES
Sbjct: 246 QMFKNDSVLDNLSRPQLAAMSKFMSLRPFGNDNMLRYQIRSKLKDIMNDDKTIDYEGVES 305
Query: 293 LDAIELRTACASRGIRNLNVEESVLRDNLKIWLNMRLKDKIPSTLLVMATAYTYGDIGSK 352
L EL AC SRG++ V + L DNLK+WL +RL+ KIPS L+V+++ +T+G + +
Sbjct: 306 LSQEELYQACVSRGMKAYGVSKEDLVDNLKVWLELRLRQKIPSVLMVLSSTFTFGGLPKE 365
Query: 353 ---------------KTLYDALCD--------VLSGIPDELYHEVKVNVVEEDS------ 383
K+ YD L D VLS IPD +Y+ K++V E S
Sbjct: 366 NYSKAFSPLAEKKETKSKYDDLLDLYYDGILQVLSSIPDPVYNVAKLDVSESKSSAAETE 425
Query: 384 -----ATNKSKMAQLKEQVEIMKEEEQQEKDAVVRVKDELSLDAVDAKTVSQTEKAAPQD 438
A K K + E+ I KEE ++ + ++ V ++T K
Sbjct: 426 AEKQVAEKKIKTEEKPEETAIPKEEATAKESVIATTASAVTPKLVVVNEKAETAKTEEIS 485
Query: 439 GEKKPHNARTESESTEATKK 458
EK+ +E+TEA +K
Sbjct: 486 QEKENAEPTDSAEATEAEEK 505
>At3g59820 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 755
Score = 239 bits (610), Expect = 6e-63
Identities = 143/391 (36%), Positives = 227/391 (57%), Gaps = 29/391 (7%)
Query: 68 VKKEAEPKLSLWAKV----KHE----AQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRR 119
+K A + WAK KHE +HYW GTKLL + +I+ RL++K++ G LSRR
Sbjct: 186 IKAVASMNRADWAKKLTHWKHEFVSTLKHYWLGTKLLWADTRISSRLLLKLAGGKSLSRR 245
Query: 120 EKIQLKRTTQDMIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLR 179
E+ QL RTT D+ RLVPF+ F++VPF E LLP+ LKLFPN+LPST++ K ++ L+
Sbjct: 246 ERQQLTRTTADIFRLVPFAVFILVPFMEFLLPVFLKLFPNMLPSTFQDKMKEEEALKRKL 305
Query: 180 KTR----SVMSEIIKENKSHFKPSNITEEQKLV--FNSFYKHVRETGEPESREQLIQVAR 233
R + E +E K S E ++ + F VR G+ ++L+ A+
Sbjct: 306 LARIEYAKFLQETAREMAKEVKHSRTGEVKQTAEDLDEFLDKVRR-GQIVHNDELLGFAK 364
Query: 234 LFTDDTVLDNLTRPYLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYEGVESL 293
LF D+ LDN++RP LV++ KY+ + P+GTD LRY +R ++ +K DD I EGV+SL
Sbjct: 365 LFNDELTLDNISRPRLVSMCKYMGISPYGTDAYLRYMLRKRLRSIKEDDKLIRAEGVDSL 424
Query: 294 DAIELRTACASRGIRNL-NVEESVLRDNLKIWLNMRLKDKIPSTLLVMATAYTYGDIGSK 352
ELR C RG+ L +VEE +R L+ W+++ L +PS+LL+++ A+T + +
Sbjct: 425 SEAELREDCRERGMLGLVSVEE--MRQQLRDWMDLSLNHSVPSSLLILSRAFT---VAGR 479
Query: 353 KTLYDALCDVLSGIPDELYHEVKVNVV--EEDSATNKSKMAQLKEQVEIMKEEEQQEKDA 410
DA+ LS +PDE+ V + + E+ + + K+ L+ Q E++KEEE++E++
Sbjct: 480 VKAEDAVRATLSSLPDEVVDTVGITSLPSEDPVSERRRKLEYLEMQEELIKEEEEKEEEE 539
Query: 411 VVRVKD------ELSLDAVDAKTVSQTEKAA 435
+ R+KD + +L + T S+ ++ A
Sbjct: 540 LTRIKDVKGGDEDKALQEMTIPTASEAQEQA 570
>Hs6912482 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 739
Score = 238 bits (608), Expect = 1e-62
Identities = 146/404 (36%), Positives = 235/404 (58%), Gaps = 25/404 (6%)
Query: 64 PALPVKKEAEPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQ 123
P E K SL +V E +HY+ G +LL ++ KIA R++ ++ G+ L+RRE+ Q
Sbjct: 139 PVYSPPAEVVVKKSLGQRVLDELKHYYHGFRLLWIDTKIAARMLWRILNGHSLTRRERRQ 198
Query: 124 LKRTTQDMIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYES--------KKDKQTKL 175
R D+ RLVPF FV+VPF E LLP+A+KLFPN+LPST+E+ KK+ + KL
Sbjct: 199 FLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTFETQSLKEERLKKELRVKL 258
Query: 176 ESLRKTRSVMSEIIKENKSHFKPSNITEEQKLVFNSFYKHVRETGEPESREQLIQVARLF 235
E + + + E+ +NK+ + T++ F+ F++ +RETGE S E++++ ++LF
Sbjct: 259 ELAKFLQDTIEEMALKNKA--AKGSATKD----FSVFFQKIRETGERPSNEEIMRFSKLF 312
Query: 236 TDDTVLDNLTRPYLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYEGVESLDA 295
D+ LDNLTRP LVA+ K + LQ GT+ LR+++ ++ +K DD I EGV+SL+
Sbjct: 313 EDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNV 372
Query: 296 IELRTACASRGIRNLNVEESVLRDNLKIWLNMRLKDKIPSTLLVMATAYTYGDIGSKKTL 355
EL+ AC +RG+R L V E LR LK WL++ L +IP++LL+++ A D S
Sbjct: 373 KELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPA-- 430
Query: 356 YDALCDVLSGIPDELYHE--VKVNVVEEDSATNKSKM-AQLKEQVEIMKEEEQQEKDAVV 412
D L L +P+ + E VKV VE + NK+K+ A L+E+ I +E ++E +
Sbjct: 431 -DQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKE----L 485
Query: 413 RVKDELSLDAVDAKTVSQTEKAAPQDGEKKPHNARTESESTEAT 456
+ + E++ D + V+ ++ + + P +SE+ + T
Sbjct: 486 QKRSEVAKDFEPERVVAAPQRPGTEPQPEMPDTV-LQSETLKDT 528
>7291797 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 1013
Score = 229 bits (583), Expect = 8e-60
Identities = 125/371 (33%), Positives = 215/371 (57%), Gaps = 10/371 (2%)
Query: 69 KKEAEPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTT 128
K A+PK L ++ E HY+ G +LL ++V I +L+ ++ G L+RRE QL+RTT
Sbjct: 172 KSVAKPKKPLRTRIWDELVHYYHGFRLLFIDVAICSKLLWRVLNGKTLTRRENKQLQRTT 231
Query: 129 QDMIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLRKTRSVMSEI 188
D+ RL+PFS F+IVPF ELLLP+ +K FP +LPST+++ D+Q KL R +++
Sbjct: 232 SDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSLSVRLEVAKF 291
Query: 189 IKENKSHF--KPSNITEEQKLVFNSFYKHVRETGEPESREQLIQVARLFTDDTVLDNLTR 246
+++ + + E+ F +F+ +R EP S +++I+ A+ F D+ LD+L+R
Sbjct: 292 LQQTLDQMPVQHKEHSSEEAKQFEAFFTKIRNPTEPVSNDEIIKFAKRFDDEITLDSLSR 351
Query: 247 PYLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYEGVESLDAIELRTACASRG 306
L A+ + + L GT +LR+++R K+ L TDD I EGV+SLD +EL+ AC +RG
Sbjct: 352 EQLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARG 411
Query: 307 IRNLNVEESVLRDNLKIWLNMRLKDKIPSTLLVMATAYTYGDIGSKKTLYDALCDVLSGI 366
+R + E LR LK W+++ L +++P TLL+++ D D L + + +
Sbjct: 412 MRAYGLTEERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISD---DSITTDKLKETIRVL 468
Query: 367 PDELYHEVKVNVVE-EDSATNKSKMAQLKEQVEIMKEEEQQEKDAVV----RVKDELSLD 421
PD + + + E E NK+K+ +KE+ ++EE ++E++ + +K+E+
Sbjct: 469 PDAVGAHTRHAIGESEGKVDNKTKIEIIKEEERKIREEREEEREETIAKRSAIKEEIPAP 528
Query: 422 AVDAKTVSQTE 432
V A+ +S ++
Sbjct: 529 YVFAEKLSGSQ 539
>At1g65540 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 398
Score = 206 bits (523), Expect = 8e-53
Identities = 118/275 (42%), Positives = 169/275 (60%), Gaps = 11/275 (4%)
Query: 75 KLSLWA-KVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTTQDMIR 133
KL W + K QHYW GTKLL +V+I++RL++K++ G LSRRE+ QL RTT D+ R
Sbjct: 126 KLRHWKDEFKSTLQHYWLGTKLLWADVRISVRLLVKLANGKGLSRRERQQLTRTTADIFR 185
Query: 134 LVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLRKTR----SVMSEII 189
LVP + F+IVPF E LLP+ LKLFPN+LPST++ K ++ L+ R + + +
Sbjct: 186 LVPVAVFIIVPFMEFLLPVFLKLFPNMLPSTFQDKMKEEEALKRRLNARMEYAKFLQDTV 245
Query: 190 KENKSHFKPSNITEEQKLV--FNSFYKHVRETGEPESREQLIQVARLFTDDTVLDNLTRP 247
KE + S E +K + F VR G S ++++ A+LF D+ LDN+ R
Sbjct: 246 KEMAKEVQTSRSGEIKKTAEDLDGFMTKVRR-GVGVSNDEILGFAKLFNDELTLDNINRS 304
Query: 248 YLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYEGVESLDAIELRTACASRGI 307
LV + KY+ + PFGTD LRY +R ++ E+K DD I EGVESL ELR AC RG+
Sbjct: 305 RLVNMCKYMGISPFGTDAYLRYMLRKRLQEIKKDDKLIKAEGVESLSEAELRQACRERGM 364
Query: 308 RNL-NVEESVLRDNLKIWLNMRLKDKIPSTLLVMA 341
L +VEE +R+ L WL++ L +PS+LL+++
Sbjct: 365 LQLGSVEE--MREQLVDWLDLSLNHSVPSSLLILS 397
>CE20894 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 770
Score = 204 bits (518), Expect = 3e-52
Identities = 126/380 (33%), Positives = 207/380 (54%), Gaps = 17/380 (4%)
Query: 69 KKEAEPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTT 128
K A K L ++ HE +HY+ G +LL LE +++ + + + G LSRRE+ QL RT
Sbjct: 82 KDVATVKPPLKDRIIHELKHYYHGFRLLALETRVSAKYLWTVLRGATLSRRERQQLVRTV 141
Query: 129 QDMIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLRKTRSVMSEI 188
D+ RLVPFS F+IVPF EL LPI +KLFP +LPST++ ++ K K R M++
Sbjct: 142 SDLFRLVPFSFFIIVPFMELALPIFIKLFPGMLPSTFQESSKEEEKWRKQVKLRVEMAKF 201
Query: 189 IKENKSHF----KPSNITEEQKLVFNSFYKHVRETGEPESREQLIQVARLFTDDTVLDNL 244
+++ K N + L F F K VR G S E+L++ ++LF D+ LDNL
Sbjct: 202 LQDTIEEIGLERKTRNKESTRSLEFALFIKKVRNEGGYVSNEELLKFSKLFEDEITLDNL 261
Query: 245 TRPYLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYE-GVESLDAIELRTACA 303
+ L ++ + +++ G+ +LR+++ K+ ELK DD I E GV++L +I+L++AC
Sbjct: 262 SMGQLRSLCRLMSINSLGSPEILRFQLNMKIRELKADDKQIAAEGGVDALSSIDLQSACR 321
Query: 304 SRGIRNLNVEESVLRDNLKIWLNMRLKDKIPSTLLVMA-TAYTYGDIGSKKTLYDALCDV 362
+RG+R + V E L++ L WL + L DK+P LL+++ T Y + + + D L +
Sbjct: 322 ARGMRAIGVSEERLKEQLVQWLELSLNDKVPPALLLLSRTLY----LPEEVSFPDRLKAI 377
Query: 363 LSGIPDELYHEVKVNVVE-EDSATNKSKMAQLKEQVEIMKEEEQQEKDAVVRVKDELSLD 421
+ +PD L K + E E + +L +E E+++++ + +E
Sbjct: 378 VQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEA--- 434
Query: 422 AVDAKTVSQTEKAAPQDGEK 441
K+ + EKA Q+ EK
Sbjct: 435 ---LKSKEEAEKAKVQEKEK 451
>CE11400 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 784
Score = 204 bits (518), Expect = 3e-52
Identities = 126/380 (33%), Positives = 207/380 (54%), Gaps = 17/380 (4%)
Query: 69 KKEAEPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTT 128
K A K L ++ HE +HY+ G +LL LE +++ + + + G LSRRE+ QL RT
Sbjct: 82 KDVATVKPPLKDRIIHELKHYYHGFRLLALETRVSAKYLWTVLRGATLSRRERQQLVRTV 141
Query: 129 QDMIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLRKTRSVMSEI 188
D+ RLVPFS F+IVPF EL LPI +KLFP +LPST++ ++ K K R M++
Sbjct: 142 SDLFRLVPFSFFIIVPFMELALPIFIKLFPGMLPSTFQESSKEEEKWRKQVKLRVEMAKF 201
Query: 189 IKENKSHF----KPSNITEEQKLVFNSFYKHVRETGEPESREQLIQVARLFTDDTVLDNL 244
+++ K N + L F F K VR G S E+L++ ++LF D+ LDNL
Sbjct: 202 LQDTIEEIGLERKTRNKESTRSLEFALFIKKVRNEGGYVSNEELLKFSKLFEDEITLDNL 261
Query: 245 TRPYLVAIAKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYE-GVESLDAIELRTACA 303
+ L ++ + +++ G+ +LR+++ K+ ELK DD I E GV++L +I+L++AC
Sbjct: 262 SMGQLRSLCRLMSINSLGSPEILRFQLNMKIRELKADDKQIAAEGGVDALSSIDLQSACR 321
Query: 304 SRGIRNLNVEESVLRDNLKIWLNMRLKDKIPSTLLVMA-TAYTYGDIGSKKTLYDALCDV 362
+RG+R + V E L++ L WL + L DK+P LL+++ T Y + + + D L +
Sbjct: 322 ARGMRAIGVSEERLKEQLVQWLELSLNDKVPPALLLLSRTLY----LPEEVSFPDRLKAI 377
Query: 363 LSGIPDELYHEVKVNVVE-EDSATNKSKMAQLKEQVEIMKEEEQQEKDAVVRVKDELSLD 421
+ +PD L K + E E + +L +E E+++++ + +E
Sbjct: 378 VQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEA--- 434
Query: 422 AVDAKTVSQTEKAAPQDGEK 441
K+ + EKA Q+ EK
Sbjct: 435 ---LKSKEEAEKAKVQEKEK 451
>Hs21389523 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 396
Score = 126 bits (317), Expect = 6e-29
Identities = 79/280 (28%), Positives = 141/280 (50%), Gaps = 47/280 (16%)
Query: 73 EPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTTQDMI 132
E K S K+ E ++Y++G LL ++ K+A R+V ++ G L+RRE+ + ++
Sbjct: 70 EGKQSYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRREEK------ 123
Query: 133 RLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLRKTRSVMSEIIKEN 192
KK KLE + + M+E+ + N
Sbjct: 124 ----------------------------------QKKKMAVKLELAKFLQETMTEMARRN 149
Query: 193 KSHFKPSNITEEQKLVFNSFYKHVRETGEPESREQLIQVARLFTDDTVLDNLTRPYLVAI 252
++ ++ +S+ K V +TG S +++++ ++LF D L++L RP LVA+
Sbjct: 150 RAKMGDASTQ------LSSYVKQV-QTGHKPSTKEIVRFSKLFEDQLALEHLDRPQLVAL 202
Query: 253 AKYINLQPFGTDVMLRYRIRYKMLELKTDDLAIYYEGVESLDAIELRTACASRGIRNLNV 312
K + LQ FGT+ +LR+++ K+ +K DD I EGV +L EL+ AC +RG+R+L +
Sbjct: 203 CKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGL 262
Query: 313 EESVLRDNLKIWLNMRLKDKIPSTLLVMATAYTYGDIGSK 352
E LR L W ++ LK+ +P +LL+++ + D+ K
Sbjct: 263 TEEQLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKPK 302
>Hs20483257 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 281
Score = 70.1 bits (170), Expect = 7e-12
Identities = 49/156 (31%), Positives = 78/156 (49%), Gaps = 13/156 (8%)
Query: 71 EAEPKLSLWAKVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTTQD 130
E P S+ +V +H + LL ++ + A + + +G+ L+ RE Q R D
Sbjct: 133 EEAPVKSVGRRVLDGLKHCYHSFSLLWMDTRTATHSLWGILSGHMLTHREHRQFVRVRAD 192
Query: 131 MIRLVPFSAFVIVPFAELLLPIALKLFPNLLPSTYESKKDKQTKLESLRKTRSVMSEIIK 190
+ LVP F +V F ELLLPI +K+FPN+L ST+E+ +S+++ R
Sbjct: 193 LFCLVPLLIFAVVLFMELLLPIIVKIFPNMLLSTFET--------QSIKEERPKKQLWGS 244
Query: 191 ENKSHFK--PSNITEEQ---KLVFNSFYKHVRETGE 221
N HF PS E + F+ F++ +RETG+
Sbjct: 245 WNWLHFSRTPSRRKETKGRTAKAFSMFFQKIRETGK 280
>At5g06220 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 813
Score = 55.1 bits (131), Expect = 2e-07
Identities = 31/110 (28%), Positives = 55/110 (49%), Gaps = 6/110 (5%)
Query: 81 KVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTTQDMIRLVPFSAF 140
++K W GT+LL + AM L+ + G EL+ +EK L+RT D+ +VP
Sbjct: 692 QLKDATTDVWQGTQLLAFDSAAAMELLRRSVVGDELTEKEKKALRRTMTDLASVVPIGVL 751
Query: 141 VIVPFAEL----LLPIALKLFPNLLPSTYESKKDKQTKLESLRKTRSVMS 186
+++P + +L + P L+PSTY + ++ L L K + + +
Sbjct: 752 MLLPVTAVGHAAMLAAIQRYVPGLIPSTYGA--ERLNLLRQLEKVKQMQT 799
>At3g11560 [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7
Length = 797
Score = 53.5 bits (127), Expect = 6e-07
Identities = 30/112 (26%), Positives = 62/112 (54%), Gaps = 5/112 (4%)
Query: 81 KVKHEAQHYWDGTKLLGLEVKIAMRLVMKMSAGYELSRREKIQLKRTTQDMIRLVPFSAF 140
K++ W GT+LL ++ A++L+ + G EL+ +EK L+RT D+ ++P
Sbjct: 676 KLREATTDVWQGTQLLAIDSAAAVQLLRRSLIGDELTGKEKKALRRTMTDLASVIPIGIL 735
Query: 141 VIVPFAEL----LLPIALKLFPNLLPSTYESKK-DKQTKLESLRKTRSVMSE 187
+++P + +L + P L+PSTY S++ + +LE +++ ++ +E
Sbjct: 736 MLLPVTAVGHAAMLAGIQRYVPGLIPSTYGSERLNLLRQLEKIKELQTNETE 787
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,616,019
Number of Sequences: 60738
Number of extensions: 998050
Number of successful extensions: 5783
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 5741
Number of HSP's gapped (non-prelim): 18
length of query: 459
length of database: 30,389,216
effective HSP length: 110
effective length of query: 349
effective length of database: 23,708,036
effective search space: 8274104564
effective search space used: 8274104564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)