ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3030 check: MH T KOG0660 Signal transduction mechanisms Mitogen-activated protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3030 1041657 1043141 495
(495 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR030c [T] KOG0660 Mitogen-activated protein kinase 727 0.0
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 493 e-139
YKL161c [T] KOG0660 Mitogen-activated protein kinase 454 e-127
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 338 1e-92
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 338 1e-92
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 328 1e-89
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 327 3e-89
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 323 4e-88
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 315 1e-85
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 314 2e-85
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 313 5e-85
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 313 5e-85
YPR054w [T] KOG0660 Mitogen-activated protein kinase 311 1e-84
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 310 2e-84
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 310 3e-84
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 309 7e-84
YLR113w [T] KOG0660 Mitogen-activated protein kinase 308 1e-83
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 308 1e-83
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 307 2e-83
CE24971 [T] KOG0660 Mitogen-activated protein kinase 307 2e-83
CE01583 [T] KOG0660 Mitogen-activated protein kinase 307 2e-83
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 304 2e-82
YGR040w [T] KOG0660 Mitogen-activated protein kinase 300 3e-81
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 299 6e-81
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 296 4e-80
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 295 1e-79
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 294 2e-79
YBL016w [T] KOG0660 Mitogen-activated protein kinase 293 4e-79
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 293 4e-79
7298087 [T] KOG0660 Mitogen-activated protein kinase 290 4e-78
CE06686 [T] KOG0660 Mitogen-activated protein kinase 286 4e-77
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 286 5e-77
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 283 3e-76
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 283 4e-76
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 280 3e-75
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 278 1e-74
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 275 1e-73
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 274 2e-73
7301110 [T] KOG0660 Mitogen-activated protein kinase 274 3e-73
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 270 5e-72
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 269 6e-72
CE06762 [T] KOG0660 Mitogen-activated protein kinase 267 2e-71
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 266 5e-71
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 261 2e-69
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 258 1e-68
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 251 2e-66
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 248 1e-65
CE17062 [T] KOG0660 Mitogen-activated protein kinase 248 1e-65
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 247 3e-65
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 247 3e-65
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 246 7e-65
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 246 7e-65
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 244 2e-64
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 243 6e-64
CE29020 [T] KOG0660 Mitogen-activated protein kinase 242 1e-63
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 241 1e-63
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 241 1e-63
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 240 3e-63
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 238 1e-62
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 238 1e-62
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 238 1e-62
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 238 2e-62
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 234 2e-61
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 234 2e-61
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 233 4e-61
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 233 4e-61
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 233 6e-61
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 231 1e-60
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 228 2e-59
7291043 [T] KOG0660 Mitogen-activated protein kinase 221 2e-57
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 213 7e-55
CE29318 [T] KOG0660 Mitogen-activated protein kinase 209 8e-54
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 199 6e-51
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 199 8e-51
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 194 2e-49
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 191 2e-48
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 187 2e-47
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 181 3e-45
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 180 5e-45
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 179 1e-44
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 179 1e-44
CE27220 [T] KOG0660 Mitogen-activated protein kinase 178 1e-44
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 178 2e-44
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 178 2e-44
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 176 6e-44
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 173 5e-43
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 173 6e-43
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 173 6e-43
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 172 1e-42
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 171 2e-42
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 171 2e-42
At5g64960 [D] KOG0600 Cdc2-related protein kinase 170 5e-42
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 169 7e-42
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 169 7e-42
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 169 7e-42
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 169 1e-41
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 167 3e-41
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 167 3e-41
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 167 4e-41
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 167 4e-41
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 166 6e-41
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 166 1e-40
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 165 2e-40
At5g10270 [D] KOG0600 Cdc2-related protein kinase 164 3e-40
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 163 5e-40
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 163 5e-40
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 163 6e-40
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 162 8e-40
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 162 1e-39
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 161 2e-39
At1g33770 [D] KOG0600 Cdc2-related protein kinase 161 2e-39
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 160 4e-39
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 160 5e-39
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 159 1e-38
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 158 2e-38
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 157 3e-38
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 157 3e-38
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 157 5e-38
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 155 1e-37
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 155 2e-37
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 154 2e-37
7296451 [D] KOG0600 Cdc2-related protein kinase 154 2e-37
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 154 3e-37
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 153 5e-37
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 153 5e-37
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 153 5e-37
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 153 7e-37
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 153 7e-37
At4g10010 [D] KOG0600 Cdc2-related protein kinase 153 7e-37
At1g09600 [D] KOG0600 Cdc2-related protein kinase 153 7e-37
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 152 9e-37
At4g22940 [D] KOG0600 Cdc2-related protein kinase 152 9e-37
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 152 9e-37
At3g05050 [D] KOG0600 Cdc2-related protein kinase 152 9e-37
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 152 1e-36
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 152 1e-36
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 152 1e-36
At1g03740 [D] KOG0600 Cdc2-related protein kinase 151 2e-36
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 151 2e-36
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 150 3e-36
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 150 3e-36
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 150 4e-36
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 150 4e-36
At1g18670 [D] KOG0600 Cdc2-related protein kinase 150 6e-36
YMR139w [G] KOG0658 Glycogen synthase kinase-3 149 9e-36
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 149 9e-36
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 149 9e-36
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 149 9e-36
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 1e-35
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 1e-35
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 149 1e-35
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 148 2e-35
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 148 2e-35
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 2e-35
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 2e-35
At5g50860 [D] KOG0600 Cdc2-related protein kinase 147 4e-35
At5g44290 [D] KOG0600 Cdc2-related protein kinase 147 4e-35
7290342 [G] KOG0658 Glycogen synthase kinase-3 147 4e-35
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 147 5e-35
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 147 5e-35
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 147 5e-35
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 146 6e-35
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 146 6e-35
At1g54610 [D] KOG0600 Cdc2-related protein kinase 146 6e-35
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 146 8e-35
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 1e-34
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 145 1e-34
At1g74330 [D] KOG0600 Cdc2-related protein kinase 145 1e-34
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 145 1e-34
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 145 1e-34
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 145 2e-34
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 145 2e-34
CE26422 [D] KOG0600 Cdc2-related protein kinase 145 2e-34
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 144 4e-34
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 143 5e-34
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 143 5e-34
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 143 5e-34
At1g57700 [D] KOG0600 Cdc2-related protein kinase 143 5e-34
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 143 7e-34
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 143 7e-34
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 142 9e-34
CE21401 [G] KOG0658 Glycogen synthase kinase-3 142 9e-34
At1g53050 [D] KOG0600 Cdc2-related protein kinase 142 9e-34
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 142 1e-33
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 142 1e-33
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 142 1e-33
YPR161c [D] KOG0600 Cdc2-related protein kinase 141 2e-33
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 140 3e-33
At1g71530 [D] KOG0600 Cdc2-related protein kinase 140 3e-33
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 140 4e-33
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 140 4e-33
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 140 4e-33
At5g39420 [D] KOG0600 Cdc2-related protein kinase 140 6e-33
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 139 7e-33
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 139 1e-32
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 139 1e-32
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 139 1e-32
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 3e-32
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 137 4e-32
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 137 4e-32
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 137 4e-32
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 136 6e-32
YDL079c [G] KOG0658 Glycogen synthase kinase-3 135 1e-31
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 135 1e-31
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 134 2e-31
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 134 3e-31
YKL139w [D] KOG0600 Cdc2-related protein kinase 132 9e-31
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 132 9e-31
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 132 1e-30
YNL307c [G] KOG0658 Glycogen synthase kinase-3 131 3e-30
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 3e-30
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 3e-30
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 131 3e-30
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 130 3e-30
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 130 6e-30
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 129 1e-29
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 127 4e-29
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 127 5e-29
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 126 7e-29
CE08727 [G] KOG0658 Glycogen synthase kinase-3 126 7e-29
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 126 9e-29
YOL128c [G] KOG0658 Glycogen synthase kinase-3 125 1e-28
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 125 1e-28
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 124 2e-28
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 124 3e-28
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 123 7e-28
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 123 7e-28
Hs18581346 [T] KOG0660 Mitogen-activated protein kinase 121 2e-27
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 120 6e-27
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 119 8e-27
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 119 1e-26
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 119 1e-26
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 119 1e-26
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 118 2e-26
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 117 4e-26
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 117 4e-26
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 116 7e-26
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 115 2e-25
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 114 3e-25
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 114 3e-25
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 1e-24
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 111 2e-24
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 111 2e-24
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 111 2e-24
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 110 4e-24
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 110 5e-24
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 110 5e-24
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 110 5e-24
CE09532 [G] KOG0658 Glycogen synthase kinase-3 110 6e-24
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 109 8e-24
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 109 1e-23
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 108 1e-23
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 108 2e-23
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 108 2e-23
CE05866 [G] KOG0658 Glycogen synthase kinase-3 107 3e-23
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 107 3e-23
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 107 3e-23
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 106 7e-23
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 106 7e-23
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 105 2e-22
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 104 3e-22
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 103 5e-22
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 102 1e-21
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 102 1e-21
At3g01090 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 102 2e-21
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 2e-21
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 101 3e-21
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 101 3e-21
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 101 3e-21
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 101 3e-21
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 101 3e-21
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 3e-21
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 101 3e-21
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 4e-21
At5g39440 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 100 7e-21
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 100 7e-21
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 100 7e-21
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 7e-21
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 9e-21
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 100 9e-21
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 100 9e-21
7298004 [G] KOG0658 Glycogen synthase kinase-3 100 9e-21
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 99 1e-20
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 3e-20
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 97 4e-20
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 97 4e-20
CE01612 [G] KOG0658 Glycogen synthase kinase-3 97 4e-20
CE20405 [G] KOG0658 Glycogen synthase kinase-3 97 6e-20
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 6e-20
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 97 6e-20
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 97 6e-20
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 97 7e-20
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 7e-20
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 96 9e-20
CE05377 [G] KOG0658 Glycogen synthase kinase-3 96 9e-20
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 9e-20
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 96 1e-19
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 96 1e-19
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 95 2e-19
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 95 2e-19
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 2e-19
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 95 2e-19
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 95 2e-19
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 3e-19
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 94 4e-19
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 94 4e-19
At3g29160 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 94 5e-19
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 94 5e-19
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 5e-19
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 94 6e-19
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 94 6e-19
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 94 6e-19
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 93 8e-19
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 93 8e-19
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 93 8e-19
At2g45490 [D] KOG0580 Serine/threonine protein kinase 93 8e-19
YPL209c [D] KOG0580 Serine/threonine protein kinase 93 1e-18
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 93 1e-18
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 93 1e-18
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 92 1e-18
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 92 1e-18
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 2e-18
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 92 2e-18
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 92 2e-18
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
At4g24400 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 91 3e-18
At4g33950 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 91 3e-18
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 91 4e-18
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 4e-18
YDR477w [T] KOG0583 Serine/threonine protein kinase 91 5e-18
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 91 5e-18
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 91 5e-18
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 90 7e-18
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 90 7e-18
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 90 7e-18
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 90 7e-18
CE28643 [T] KOG0583 Serine/threonine protein kinase 90 7e-18
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 90 7e-18
7302570 [R] KOG0586 Serine/threonine protein kinase 90 7e-18
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 90 9e-18
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 90 9e-18
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 90 9e-18
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 89 1e-17
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 89 1e-17
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 89 1e-17
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 89 2e-17
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 89 2e-17
At5g35410 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 89 2e-17
YCL024w [T] KOG0583 Serine/threonine protein kinase 89 2e-17
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 89 2e-17
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 89 2e-17
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 89 2e-17
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 89 2e-17
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 88 3e-17
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 88 3e-17
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 88 3e-17
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 88 3e-17
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 88 3e-17
CE07458 [T] KOG0583 Serine/threonine protein kinase 88 3e-17
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 88 3e-17
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 4e-17
At2g38490 [T] KOG0583 Serine/threonine protein kinase 87 4e-17
At2g30360 [T] KOG0583 Serine/threonine protein kinase 87 4e-17
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 87 6e-17
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 87 6e-17
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 87 6e-17
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 87 6e-17
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 87 6e-17
CE27768 [R] KOG0586 Serine/threonine protein kinase 87 6e-17
CE23838 [R] KOG0586 Serine/threonine protein kinase 87 6e-17
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 6e-17
YDR507c [D] KOG0588 Serine/threonine protein kinase 87 7e-17
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 87 7e-17
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 87 7e-17
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 7e-17
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 87 7e-17
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 86 1e-16
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 86 1e-16
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 86 1e-16
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 86 1e-16
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 86 1e-16
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 86 1e-16
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 86 1e-16
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 86 1e-16
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 86 1e-16
At5g28290 [R] KOG0589 Serine/threonine protein kinase 86 2e-16
At3g50500 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 86 2e-16
7295638 [T] KOG0603 Ribosomal protein S6 kinase 86 2e-16
YDL028c [D] KOG0596 Dual specificity; serine/threonine and tyros... 85 2e-16
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 85 2e-16
At1g01140 [T] KOG0583 Serine/threonine protein kinase 85 2e-16
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 85 2e-16
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 85 3e-16
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 85 3e-16
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 85 3e-16
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 84 4e-16
Hs22066955 [T] KOG0660 Mitogen-activated protein kinase 84 4e-16
At1g30270 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 84 5e-16
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 84 5e-16
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 84 5e-16
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 84 5e-16
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 84 5e-16
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 84 5e-16
At2g25880 [D] KOG0580 Serine/threonine protein kinase 84 5e-16
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 5e-16
At1g54510 [R] KOG0589 Serine/threonine protein kinase 84 5e-16
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 84 5e-16
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 84 5e-16
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 84 6e-16
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 84 6e-16
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 84 6e-16
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 84 6e-16
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 84 6e-16
At5g45810 [T] KOG0583 Serine/threonine protein kinase 84 6e-16
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 6e-16
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 6e-16
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 83 8e-16
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 83 8e-16
At5g66880 [T] KOG0583 Serine/threonine protein kinase 83 8e-16
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 83 8e-16
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 83 1e-15
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
CE28218 [D] KOG0588 Serine/threonine protein kinase 83 1e-15
CE23001 [R] KOG0589 Serine/threonine protein kinase 83 1e-15
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 1e-15
At4g18700 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 83 1e-15
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 82 1e-15
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 1e-15
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 82 1e-15
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 82 1e-15
At3g04810 [R] KOG0589 Serine/threonine protein kinase 82 1e-15
7294217 [D] KOG0588 Serine/threonine protein kinase 82 1e-15
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 1e-15
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 82 2e-15
At3g17510 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 82 2e-15
CE18454 [T] KOG4717 Serine/threonine protein kinase 82 2e-15
At4g32830 [D] KOG0580 Serine/threonine protein kinase 82 2e-15
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 82 2e-15
7299793 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 82 2e-15
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 81 3e-15
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 81 3e-15
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 81 3e-15
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 81 3e-15
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 81 3e-15
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 81 3e-15
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 81 3e-15
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 81 3e-15
7293601 [T] KOG0577 Serine/threonine protein kinase 81 3e-15
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 81 4e-15
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 81 4e-15
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 81 4e-15
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 81 4e-15
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 4e-15
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 4e-15
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 81 4e-15
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 81 4e-15
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 80 5e-15
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 80 5e-15
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 80 5e-15
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 80 5e-15
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 80 5e-15
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 80 5e-15
CE01405 [T] KOG0577 Serine/threonine protein kinase 80 5e-15
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 80 7e-15
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 80 7e-15
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 7e-15
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 80 7e-15
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 80 7e-15
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 727 bits (1877), Expect = 0.0
Identities = 351/453 (77%), Positives = 394/453 (86%), Gaps = 7/453 (1%)
Query: 5 DAVDRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSK 64
D ++RHTFKVFNQDF+VDKRFQLIKEIGHG+YGIVCSARF EAA++TTVAIKKVTNVFSK
Sbjct: 3 DKIERHTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSK 62
Query: 65 TLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSG 124
TLLCKRSLRELKLLRHFRGHKNITCLYDMDIVF PDG NGLYLYEELMECDMHQI+KSG
Sbjct: 63 TLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG 122
Query: 125 QPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENP 184
QPLTDAHYQSF YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENP
Sbjct: 123 QPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENP 182
Query: 185 VENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQL 244
VEN+QFLTEYVATRWYRAPEIMLSYQGYTKAIDVWS GCILAE LGGKPIFKGKDYV+QL
Sbjct: 183 VENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQL 242
Query: 245 NRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFD 304
N+ILQVLGTPP+ETL+RIGSKNVQDYIHQLG+IPK+PF LYPNAN AL+LLE ML+FD
Sbjct: 243 NQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFD 302
Query: 305 PQLRITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYV 364
PQ RITVD+AL+HPYLSIWHDPADEP+C+EKF+FSFESVN++E LKQMVI EV DFR +V
Sbjct: 303 PQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVNDMEDLKQMVIQEVQDFRLFV 362
Query: 365 RLPLLHEQQQQQGKTDGGFDDQIREDQRTFQAQLEEQVNNGRTASNVPSFDEPFSSQMMG 424
R PLL EQ+Q Q + Q ++ Q+ Q Q V+NG A++ ++ + ++
Sbjct: 363 RQPLLEEQRQLQLQ-----QQQQQQQQQQQQQQQPSDVDNGNAAASEENYPKQMATS--N 415
Query: 425 SASQQDPLVGIHSDNLPSHELDFPPRPSENVLD 457
S + Q GIHS NLP H+ DFPPRP E++++
Sbjct: 416 SVAPQQESFGIHSQNLPRHDADFPPRPQESMME 448
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 493 bits (1269), Expect = e-139
Identities = 233/358 (65%), Positives = 289/358 (80%), Gaps = 3/358 (0%)
Query: 9 RH-TFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLL 67
RH ++VFNQ+ V+ F+++KE+G G+YGIVC+AR + D+ VAIKK+TNVFSK++L
Sbjct: 4 RHRVYRVFNQEMYVEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSIL 63
Query: 68 CKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL 127
KR+LRE+KLL HFR H+NITC+YD+DI+ + FN +Y+YEELME D++ I+KSGQPL
Sbjct: 64 TKRALREIKLLIHFRNHRNITCIYDLDIINPYN--FNEVYIYEELMEADLNAIIKSGQPL 121
Query: 128 TDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVEN 187
TDAH+QSFIYQILCGLKYIHSA+V+HRDLKPGNLLVNADC+LKICDFGLARG SENP EN
Sbjct: 122 TDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEEN 181
Query: 188 NQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRI 247
F+TEYVATRWYRAPEIMLS+ Y K IDVWS GCILAELLGG P+FKGKD+V QLN I
Sbjct: 182 PGFMTEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLI 241
Query: 248 LQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQL 307
L LGTP EETL I S Q+Y+ L IPF T +P ANP AL+LL +L+FDP
Sbjct: 242 LHQLGTPDEETLSHISSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNR 301
Query: 308 RITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVR 365
RI+VDDAL+HPYL++WHDP+DEP+C FDFSFE + + +L+++++DEV +FRQ VR
Sbjct: 302 RISVDDALEHPYLAVWHDPSDEPVCDSVFDFSFEYIEDANELRRVILDEVLNFRQKVR 359
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 454 bits (1168), Expect = e-127
Identities = 217/358 (60%), Positives = 272/358 (75%)
Query: 8 DRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLL 67
+R F+ F QDF ++K F L +IG GS+ ++CS+ +TE+ +ET VAI+K+ N F L
Sbjct: 6 ERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLS 65
Query: 68 CKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL 127
CKR+LRELKLLRH RGH NI L+D DIVF P+G NG+YLYEELMECD+ QI++S Q L
Sbjct: 66 CKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRL 125
Query: 128 TDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVEN 187
DAH+QSFIYQILC LKYIHSA+VLH DLKP NLLVN+DCQLKIC+FGL+ YSEN N
Sbjct: 126 EDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVN 185
Query: 188 NQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRI 247
+ F+ Y+ + WY+APEI+L+YQ TKA+D+WS GCILAELLG KP+F+GKDYVD LN I
Sbjct: 186 DGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHI 245
Query: 248 LQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQL 307
LQ+LGTPPEETL+ I S+ V +YI Q G IP F ++ P ANP+AL LL+ ML FDP+
Sbjct: 246 LQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKK 305
Query: 308 RITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVR 365
RITV+DAL+HPYLS+WHD +E C + F F FE + + +L VI EV DFR+ VR
Sbjct: 306 RITVEDALEHPYLSMWHDIDEEFSCQKTFRFEFEHIESMAELGNEVIKEVFDFRKVVR 363
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 338 bits (866), Expect = 1e-92
Identities = 174/375 (46%), Positives = 245/375 (64%), Gaps = 7/375 (1%)
Query: 15 FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
F+ F V +++I+ IG+G+YG+V SAR + VAIKK+ N F KR+LRE
Sbjct: 45 FDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ--VAIKKIPNAFDVVTNAKRTLRE 102
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQS 134
LK+L+HF+ H NI + D+ P G F +Y+ +LME D+HQI+ S QPLT H +
Sbjct: 103 LKILKHFK-HDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRY 161
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
F+YQ+L GLKY+HSA V+HRDLKP NLLVN +C+LKI DFG+ARG +P E+ F+TEY
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
VATRWYRAPE+MLS YT+AID+WS GCI E+L + +F GK+YV QL I+ VLGTP
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTP 281
Query: 255 PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDA 314
++ +G++ V+ YI L +P+ T+YP A+ AL+LL ML F+P RI+ A
Sbjct: 282 SPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAA 341
Query: 315 LQHPYLSIWHDPADEPICTEKFDFSFE-SVNEIEQLKQMVIDEVTDF---RQYVRLPLLH 370
L+HP+L+ +HDP DEP C FDF+F+ E++K+ ++ E+ DF R+ +R +
Sbjct: 342 LRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRF 401
Query: 371 EQQQQQGKTDGGFDD 385
+ Q ++ G D
Sbjct: 402 QPSLQPVASEPGCPD 416
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 338 bits (866), Expect = 1e-92
Identities = 174/375 (46%), Positives = 245/375 (64%), Gaps = 7/375 (1%)
Query: 15 FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
F+ F V +++I+ IG+G+YG+V SAR + VAIKK+ N F KR+LRE
Sbjct: 45 FDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQ--VAIKKIPNAFDVVTNAKRTLRE 102
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQS 134
LK+L+HF+ H NI + D+ P G F +Y+ +LME D+HQI+ S QPLT H +
Sbjct: 103 LKILKHFK-HDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRY 161
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
F+YQ+L GLKY+HSA V+HRDLKP NLLVN +C+LKI DFG+ARG +P E+ F+TEY
Sbjct: 162 FLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEY 221
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
VATRWYRAPE+MLS YT+AID+WS GCI E+L + +F GK+YV QL I+ VLGTP
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTP 281
Query: 255 PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDA 314
++ +G++ V+ YI L +P+ T+YP A+ AL+LL ML F+P RI+ A
Sbjct: 282 SPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAA 341
Query: 315 LQHPYLSIWHDPADEPICTEKFDFSFE-SVNEIEQLKQMVIDEVTDF---RQYVRLPLLH 370
L+HP+L+ +HDP DEP C FDF+F+ E++K+ ++ E+ DF R+ +R +
Sbjct: 342 LRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRF 401
Query: 371 EQQQQQGKTDGGFDD 385
+ Q ++ G D
Sbjct: 402 QPSLQPVASEPGCPD 416
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 328 bits (840), Expect = 1e-89
Identities = 172/362 (47%), Positives = 239/362 (65%), Gaps = 18/362 (4%)
Query: 3 EYDAVDRH-----TFKVFNQDFTVDKRFQL-IKEIGHGSYGIVCSARFTEAADETTVAIK 56
++ AV+ H ++ +F F + +++ I IG G+YGIVCS TE + VA+K
Sbjct: 10 DFPAVETHGGQFISYDIFGSLFEITSKYRPPIIPIGRGAYGIVCSVLDTETNE--LVAMK 67
Query: 57 KVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQP-DGMFNGLYLYEELMEC 115
K+ N F + KR+LRE+KLLRH H+NI + D+V P F+ +Y+ ELM+
Sbjct: 68 KIANAFDNHMDAKRTLREIKLLRHL-DHENIIAI--RDVVPPPLRRQFSDVYISTELMDT 124
Query: 116 DMHQIVKSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFG 175
D+HQI++S Q L++ H Q F+YQ+L GLKYIHSA+++HRDLKP NLL+NA+C LKICDFG
Sbjct: 125 DLHQIIRSNQSLSEEHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFG 184
Query: 176 LARGYSENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIF 235
LAR P N F+TEYV TRWYRAPE++L+ YT AIDVWS GCI EL+ KP+F
Sbjct: 185 LAR-----PTSENDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLF 239
Query: 236 KGKDYVDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALN 295
GKD+V Q+ + ++LGTP E L +++ + YI QL P+ P + L+ + NP A++
Sbjct: 240 PGKDHVHQMRLLTELLGTPTESDLGFTHNEDAKRYIRQLPNFPRQPLAKLFSHVNPMAID 299
Query: 296 LLEGMLSFDPQLRITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVN-EIEQLKQMVI 354
L++ ML+FDP RITV+ AL H YL+ HDP DEPIC + F F FE + EQ+K+M+
Sbjct: 300 LVDRMLTFDPNRRITVEQALNHQYLAKLHDPNDEPICQKPFSFEFEQQPLDEEQIKEMIY 359
Query: 355 DE 356
E
Sbjct: 360 QE 361
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 327 bits (837), Expect = 3e-89
Identities = 176/352 (50%), Positives = 240/352 (68%), Gaps = 14/352 (3%)
Query: 12 FKVFNQDFTVDKRFQL-IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR 70
+ +F F V +++ I IG G+YGIVCSA +E + +VAIKK+ N F + KR
Sbjct: 49 YNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAMNSETNE--SVAIKKIANAFDNKIDAKR 106
Query: 71 SLRELKLLRHFRGHKNITCLYDMDIVFQP-DGMFNGLYLYEELMECDMHQIVKSGQPLTD 129
+LRE+KLLRH H+NI + DI+ P FN +Y+ ELM+ D+HQI++S Q L++
Sbjct: 107 TLREIKLLRHM-DHENIVAI--RDIIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQALSE 163
Query: 130 AHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ 189
H Q F+YQIL GLKYIHSA+VLHRDLKP NLL+NA+C LKICDFGLAR SE +
Sbjct: 164 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSE-----SD 218
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
F+TEYV TRWYRAPE++L+ YT AIDVWS GCI EL+ KP+F G+D+V QL +++
Sbjct: 219 FMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLME 278
Query: 250 VLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRI 309
++GTP EE L+ + ++N + YI QL P+ + +P +P A++L+E ML+FDP+ RI
Sbjct: 279 LIGTPSEEELEFL-NENAKRYIRQLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRI 337
Query: 310 TVDDALQHPYLSIWHDPADEPICTEKFDFSFES-VNEIEQLKQMVIDEVTDF 360
TV DAL HPYL+ HD +DEP CT F+F FE+ EQ+K+++ E F
Sbjct: 338 TVLDALAHPYLNSLHDISDEPECTIPFNFDFENHALSEEQMKELIYREALAF 389
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 323 bits (828), Expect = 4e-88
Identities = 167/351 (47%), Positives = 235/351 (66%), Gaps = 11/351 (3%)
Query: 12 FKVFNQDFTVDKRF-QLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR 70
+ V+ F V +++ ++ IG G+YGIVC+A +E +E VAIKK+ N F + KR
Sbjct: 29 YNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEE--VAIKKIGNAFDNIIDAKR 86
Query: 71 SLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDA 130
+LRE+KLL+H H+N+ + D+ Q + FN +Y+ ELM+ D+HQI++S QPLTD
Sbjct: 87 TLREIKLLKHM-DHENVIAVKDIIKPPQREN-FNDVYIVYELMDTDLHQIIRSNQPLTDD 144
Query: 131 HYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQF 190
H + F+YQ+L GLKY+HSA+VLHRDLKP NLL+NA+C LK+ DFGLAR SE F
Sbjct: 145 HCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSET-----DF 199
Query: 191 LTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQV 250
+TEYV TRWYRAPE++L+ YT AID+WS GCIL E + +P+F GKDYV QL I ++
Sbjct: 200 MTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITEL 259
Query: 251 LGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRIT 310
+G+P + +L + S N + Y+ QL P+ F+ +PN + A++LLE ML FDP RIT
Sbjct: 260 IGSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRIT 319
Query: 311 VDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQ-LKQMVIDEVTDF 360
VD+AL HPYL+ HD +EP+C F+F FE E+ +K+++ E F
Sbjct: 320 VDEALCHPYLAPLHDINEEPVCVRPFNFDFEQPTLTEENIKELIYRETVKF 370
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 315 bits (806), Expect = 1e-85
Identities = 170/349 (48%), Positives = 229/349 (64%), Gaps = 11/349 (3%)
Query: 9 RHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLC 68
+H F ++ F +D ++ IK IG G+YG+VCS+ E+ + VAIKK+ NVF +
Sbjct: 16 KHYFSMWQTLFEIDTKYVPIKPIGRGAYGVVCSSVNRESNER--VAIKKIHNVFENRIDA 73
Query: 69 KRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLT 128
R+LRELKLLRH R H+N+ L D+ ++ F +YL ELM+ D+HQI+KS Q L+
Sbjct: 74 LRTLRELKLLRHLR-HENVVALKDV-MMANHKRSFKDVYLVYELMDTDLHQIIKSSQVLS 131
Query: 129 DAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENN 188
+ H Q F++Q+L GLKYIHSA++LHRDLKPGNLLVNA+C LKICDFGLAR +
Sbjct: 132 NDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTK----G 187
Query: 189 QFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRIL 248
QF+TEYV TRWYRAPE++L Y +IDVWS GCI AELLG KP+F G + ++Q+ I+
Sbjct: 188 QFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLII 247
Query: 249 QVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLR 308
+LG+ EE L+ I + + YI L Y P I FS LYP AN A++LL+ ML DP R
Sbjct: 248 NILGSQREEDLEFIDNPKAKRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKR 307
Query: 309 ITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEV 357
I+V +ALQHPY++ +DP+ P D V+E E L +I E+
Sbjct: 308 ISVTEALQHPYMAPLYDPSANPPAQVPIDL---DVDEDEDLGAEMIREL 353
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 314 bits (805), Expect = 2e-85
Identities = 165/352 (46%), Positives = 231/352 (64%), Gaps = 8/352 (2%)
Query: 9 RHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLC 68
+H F ++ F +D ++ IK IG G+YG+VCS+ ++ ++ VAIKK+ NV+ +
Sbjct: 16 KHYFSMWQTLFEIDTKYMPIKPIGRGAYGVVCSSVNSDTNEK--VAIKKIHNVYENRIDA 73
Query: 69 KRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLT 128
R+LRELKLLRH R H+N+ L D+ + F +YL ELM+ D+HQI+KS Q L+
Sbjct: 74 LRTLRELKLLRHLR-HENVIALKDVMMPIHKMS-FKDVYLVYELMDTDLHQIIKSSQVLS 131
Query: 129 DAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENN 188
+ H Q F++Q+L GLKYIHSA++LHRDLKPGNLLVNA+C LKICDFGLAR +
Sbjct: 132 NDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTK----G 187
Query: 189 QFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRIL 248
QF+TEYV TRWYRAPE++L Y +IDVWS GCI AELLG KPIF+G + ++QL I+
Sbjct: 188 QFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIV 247
Query: 249 QVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLR 308
+LG+ EE L+ I + + YI L Y P + S LYP A+ A++LL+ ML FDP R
Sbjct: 248 NILGSQREEDLEFIDNPKAKRYIRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKR 307
Query: 309 ITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDF 360
I+V +ALQHPY++ +DP P D + E +++M+ +E+ +
Sbjct: 308 ISVSEALQHPYMAPLYDPNANPPAQVPIDLDVDEDLREEMIREMMWNEMLHY 359
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 313 bits (801), Expect = 5e-85
Identities = 170/351 (48%), Positives = 243/351 (68%), Gaps = 12/351 (3%)
Query: 14 VFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLR 73
V Q F V R+ + IG G+YG+VCSA + ++ VAIKK++ F C+R+LR
Sbjct: 14 VRGQVFDVGPRYTNLSYIGEGAYGMVCSAY--DNVNKVRVAIKKISP-FEHQTYCQRTLR 70
Query: 74 ELKLLRHFRGHKNITCLYDMDIVFQPD-GMFNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
E+K+L FR H+NI + D I+ P +Y+ ++LME D+++++K+ Q L++ H
Sbjct: 71 EIKILLRFR-HENIIGIND--IIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHI 126
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
F+YQIL GLKYIHSA+VLHRDLKP NLL+N C LKICDFGLAR ++ ++ FLT
Sbjct: 127 CYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLT 185
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
EYVATRWYRAPEIML+ +GYTK+ID+WS GCILAE+L +PIF GK Y+DQLN IL +LG
Sbjct: 186 EYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILG 245
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
+P +E L I + ++Y+ L + K+P++ L+PNA+ AL+LL+ ML+F+P RI V+
Sbjct: 246 SPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVE 305
Query: 313 DALQHPYLSIWHDPADEPICTEKFDFSFESVNEI--EQLKQMVIDEVTDFR 361
AL HPYL ++DP+DEPI F F E ++++ E+LK+++ +E F+
Sbjct: 306 QALAHPYLEQYYDPSDEPIAEAPFKFDME-LDDLPKEKLKELIFEETARFQ 355
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 313 bits (801), Expect = 5e-85
Identities = 170/351 (48%), Positives = 233/351 (65%), Gaps = 12/351 (3%)
Query: 12 FKVFNQDFTVDKRFQL-IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR 70
+ +F F + +++ I+ IG G+ GIVCSA +E ++ VAIKK+T VF T+ KR
Sbjct: 46 YNLFGHIFELPAKYKPPIRPIGRGACGIVCSAVDSETNEK--VAIKKITQVFDNTIEAKR 103
Query: 71 SLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDA 130
+LRE+KLLRHF H+NI + D+ + Q D F +Y+ ELME D+++ +KS Q LT
Sbjct: 104 TLREIKLLRHF-DHENIVAIRDVILPPQRDS-FEDVYIVNELMEFDLYRTLKSDQELTKD 161
Query: 131 HYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQF 190
H F+YQIL GLKYIHSA+VLHRDLKP NLL++ C LKICDFGLAR E +
Sbjct: 162 HGMYFMYQILRGLKYIHSANVLHRDLKPSNLLLSTQCDLKICDFGLARATPE-----SNL 216
Query: 191 LTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQV 250
+TEYV TRWYRAPE++L YT AIDVWS GCI E++ +P+F GKD V+QL +L++
Sbjct: 217 MTEYVVTRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLEL 276
Query: 251 LGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRIT 310
+GTP EE L + S+ + YI QL +P+ F+ +PN P A++L+E ML+FDP+ RI+
Sbjct: 277 IGTPSEEELGSL-SEYAKRYIRQLPTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRIS 335
Query: 311 VDDALQHPYLSIWHDPADEPICTEKFDFSF-ESVNEIEQLKQMVIDEVTDF 360
V +AL HPYLS +HD DEP C+E F+F E EQ ++++ E F
Sbjct: 336 VKEALAHPYLSSFHDITDEPECSEPFNFDLDEHPFSEEQFRELIYCEALAF 386
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 311 bits (797), Expect = 1e-84
Identities = 152/350 (43%), Positives = 240/350 (68%), Gaps = 20/350 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+++I+ +G G+YG VCS +F + +A+KK++N+F+K +L KR++RELK + F+GH
Sbjct: 38 YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGH 97
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
KNI L D++IV ++GLY Y+EL++ D+ +++ S L++ H + F+YQILCGLK
Sbjct: 98 KNIVNLIDLEIV--TSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLK 155
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ----FLTEYVATRWY 200
YIHSADV+HRDLKPGN+L + LKICDFGLARG + + +T YVATRWY
Sbjct: 156 YIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWY 215
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPE++LS Q Y+K++D+W+ GCILAE KP+F G+D + Q+ I++VLGTP ++ L
Sbjct: 216 RAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILI 275
Query: 261 RIGS-------KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDD 313
+ G+ KN + +++ KIP+S ++P A+ +A+NL+E +L +D R+ V+
Sbjct: 276 KFGTIKAWNLGKNSNNPVYK-----KIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQ 330
Query: 314 ALQHPYLSIWHDPADEPICTE-KFDFSFES-VNEIEQLKQMVIDEVTDFR 361
A+ HP+L+ P DEP+C + FDF++ES +N + +L+ +++EV +F+
Sbjct: 331 AISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNFK 380
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 310 bits (795), Expect = 2e-84
Identities = 169/351 (48%), Positives = 242/351 (68%), Gaps = 12/351 (3%)
Query: 14 VFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLR 73
V Q F V R+ + IG G+YG+VCSA + ++ VAIKK++ F C+R+LR
Sbjct: 14 VRGQVFDVGPRYTNLSYIGEGAYGMVCSAY--DNVNKVRVAIKKISP-FEHQTYCQRTLR 70
Query: 74 ELKLLRHFRGHKNITCLYDMDIVFQPD-GMFNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
E+K+L FR H+NI + D I+ P +Y+ ++LME D+++++K+ Q L++ H
Sbjct: 71 EIKILLRFR-HENIIGIND--IIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHI 126
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
F+YQIL GLKYIHSA+VLHRDLKP NLL+N C LKICDFGLAR ++ ++ FLT
Sbjct: 127 CYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLT 185
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
EYVATRWYRAPEIML+ +GYTK+ID+WS GCILAE+L +PIF GK Y+DQL IL +LG
Sbjct: 186 EYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILG 245
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
+P +E L I + ++Y+ L + K+P++ L+PNA+ AL+LL+ ML+F+P RI V+
Sbjct: 246 SPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVE 305
Query: 313 DALQHPYLSIWHDPADEPICTEKFDFSFESVNEI--EQLKQMVIDEVTDFR 361
AL HPYL ++DP+DEPI F F E ++++ E+LK+++ +E F+
Sbjct: 306 QALAHPYLEQYYDPSDEPIAEAPFKFDME-LDDLPKEKLKELIFEETARFQ 355
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 310 bits (794), Expect = 3e-84
Identities = 166/350 (47%), Positives = 242/350 (68%), Gaps = 10/350 (2%)
Query: 14 VFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLR 73
V Q F V R+ ++ IG G+YG+V SA + +T VAIKK++ F C+R+LR
Sbjct: 31 VKGQPFDVGPRYTQLQYIGEGAYGMVSSAY--DHVRKTRVAIKKISP-FEHQTYCQRTLR 87
Query: 74 ELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQ 133
E+++L FR H+N+ + D+ + M +Y+ ++LME D+++++KS Q L++ H
Sbjct: 88 EIQILLRFR-HENVIGIRDILRASTLEAM-RDVYIVQDLMETDLYKLLKS-QQLSNDHIC 144
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
F+YQIL GLKYIHSA+VLHRDLKP NLL+N C LKICDFGLAR ++ ++ FLTE
Sbjct: 145 YFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTE 203
Query: 194 YVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGT 253
YVATRWYRAPEIML+ +GYTK+ID+WS GCILAE+L +PIF GK Y+DQLN IL +LG+
Sbjct: 204 YVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGS 263
Query: 254 PPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDD 313
P +E L I + ++Y+ L K+ ++ L+P ++ AL+LL+ ML+F+P RITV++
Sbjct: 264 PSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEE 323
Query: 314 ALQHPYLSIWHDPADEPICTEKFDFSFESVNEI--EQLKQMVIDEVTDFR 361
AL HPYL ++DP DEP+ E F F+ E ++++ E+LK+++ E F+
Sbjct: 324 ALAHPYLEQYYDPTDEPVAEEPFTFAME-LDDLPKERLKELIFQETARFQ 372
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 309 bits (791), Expect = 7e-84
Identities = 157/314 (50%), Positives = 222/314 (70%), Gaps = 9/314 (2%)
Query: 18 DFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKL 77
+F + + +++I IG G+YG+VC+A + VA+KK+ + F+ + C R+LRE+KL
Sbjct: 32 NFELPEEYEMINLIGQGAYGVVCAALHKPSG--LKVAVKKI-HPFNHPVFCLRTLREIKL 88
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFI 136
LRHFR H+NI + +DI+ P +Y+ +ELME D++++++S QPL+D H Q F
Sbjct: 89 LRHFR-HENIISI--LDILPPPSYQELEDVYIVQELMETDLYRVIRS-QPLSDDHCQYFT 144
Query: 137 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVA 196
YQIL LK +HSA V+HRDLKP NLL+NA+C LK+ DFGLAR + N F+TEYVA
Sbjct: 145 YQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQG-GNPGFMTEYVA 203
Query: 197 TRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPE 256
TRWYRAPEIMLS++ Y+KAID+WS GCILAE+L +P+F GKDY Q+ IL +LGTP
Sbjct: 204 TRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTM 263
Query: 257 ETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQ 316
+ RI S + YI L + PK+ F L+P A+PDA++LLE +L+F+P RIT ++AL+
Sbjct: 264 DDFSRIKSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALK 323
Query: 317 HPYLSIWHDPADEP 330
HPY++ +HD +DEP
Sbjct: 324 HPYVAAYHDASDEP 337
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 308 bits (789), Expect = 1e-83
Identities = 171/406 (42%), Positives = 245/406 (60%), Gaps = 33/406 (8%)
Query: 13 KVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSL 72
++F F + R+ + +G G++G+VCSA T+ VAIKK+ FS +L KR+
Sbjct: 11 QIFGTVFEITNRYNDLNPVGMGAFGLVCSA--TDTLTSQPVAIKKIMKPFSTAVLAKRTY 68
Query: 73 RELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
RELKLL+H R H+N+ CL DI P +Y EL D+H+++++ +PL
Sbjct: 69 RELKLLKHLR-HENLICL--QDIFLSP---LEDIYFVTELQGTDLHRLLQT-RPLEKQFV 121
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
Q F+YQIL GLKY+HSA V+HRDLKP N+L+N +C LKICDFGLAR +++ Q +T
Sbjct: 122 QYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR------IQDPQ-MT 174
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
YV+TR+YRAPEIML++Q Y +D+WS GCI AE++ GKP+F GKD+V Q + I +LG
Sbjct: 175 GYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG 234
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
+PP++ + I S+N ++ L + IPFS + PDA++LLE ML FDP+ RIT
Sbjct: 235 SPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAA 294
Query: 313 DALQHPYLSIWHDPADEPICTEKFDFSFESVN-EIEQLKQMVIDEVTDFRQYVRLPLLHE 371
DAL HPY + +HDP DEP+ KFD+ F + ++ + M+ E+ DF H+
Sbjct: 295 DALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDF---------HK 345
Query: 372 QQQQQGKTD--GGFDDQI-----REDQRTFQAQLEEQVNNGRTASN 410
G+ D FDDQ+ Q QAQ + Q+N + N
Sbjct: 346 IGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHN 391
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 308 bits (789), Expect = 1e-83
Identities = 165/335 (49%), Positives = 218/335 (64%), Gaps = 10/335 (2%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
I+ IG G+YGIVC A +E +E VAIKK+ N F + KR+LRE+KLL H H N+
Sbjct: 36 IEPIGRGAYGIVCCATNSETNEE--VAIKKIANAFDNRVDAKRTLREIKLLSHM-DHDNV 92
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIH 147
+ D+ I F +Y+ ELM+ D+HQI++S Q LTD H Q F+YQIL GLKYIH
Sbjct: 93 IKIKDI-IELPEKERFEDVYIVYELMDTDLHQIIRSTQTLTDDHCQYFLYQILRGLKYIH 151
Query: 148 SADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIML 207
SA+VLHRDLKP NL++N +C LKICDFGLAR +E + +TEYV TRWYRAPE++L
Sbjct: 152 SANVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETEI-----MTEYVVTRWYRAPELLL 206
Query: 208 SYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKNV 267
+ YT AID+WS GCI E+L + +F GKDYV QL I ++LG+P + L + S N
Sbjct: 207 NSSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSDLDFLRSDNA 266
Query: 268 QDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPA 327
+ Y+ QL ++ K F +PN +P AL+L E ML FDP RITVD+AL+ PYL+ H+
Sbjct: 267 RKYVKQLPHVQKQSFREKFPNISPMALDLAEKMLVFDPSKRITVDEALKQPYLASLHEIN 326
Query: 328 DEPICTEKFDFSFESVNEIEQ-LKQMVIDEVTDFR 361
+EP C F F FE EQ +K++V E F+
Sbjct: 327 EEPTCPTPFSFDFEETALDEQDIKELVWRESLHFK 361
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 307 bits (787), Expect = 2e-83
Identities = 161/349 (46%), Positives = 232/349 (66%), Gaps = 17/349 (4%)
Query: 13 KVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSL 72
++F F + R+ ++ IG G++G+VCSA+ + VA+KK+ FS +L KR+
Sbjct: 8 QIFGTCFEITTRYSDLQPIGMGAFGLVCSAK--DQLTGMNVAVKKIMKPFSTPVLAKRTY 65
Query: 73 RELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
RELKLL+H R H+NI L D+ I F +Y EL+ D+H+++ S +PL
Sbjct: 66 RELKLLKHLR-HENIISLSDIFI-----SPFEDIYFVTELLGTDLHRLLTS-RPLETQFI 118
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
Q F+YQIL GLK++HSA V+HRDLKP N+L+N +C LKICDFGLAR +++ Q +T
Sbjct: 119 QYFLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLAR------IQDPQ-MT 171
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
YV+TR+YRAPEIML++Q Y +D+WS GCI AE++ GKP+F G+D+V+Q + I ++LG
Sbjct: 172 GYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLG 231
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
TPP E ++ I SKN ++ L K+PF+ + NA+PDA++LLE ML FDP+ RI+
Sbjct: 232 TPPMEVIETICSKNTLRFVQSLPQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAA 291
Query: 313 DALQHPYLSIWHDPADEPICTEKFDFSFESVN-EIEQLKQMVIDEVTDF 360
DAL H YL+ +HDP DEP+ E FD+SF+ + +E K M+ EV F
Sbjct: 292 DALAHNYLAPYHDPTDEPVADEVFDWSFQDNDLPVETWKVMMYSEVLSF 340
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 307 bits (787), Expect = 2e-83
Identities = 167/346 (48%), Positives = 237/346 (68%), Gaps = 10/346 (2%)
Query: 13 KVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSL 72
+V Q F V R+ + IG G+YG+V SA T D VAIKK++ F C+R+L
Sbjct: 84 EVHGQLFEVAPRYVNLSYIGEGAYGMVASALDTITRDR--VAIKKISP-FEHQTFCQRTL 140
Query: 73 RELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
RE+K+L F+ H+NI + ++ I + +Y+ + LME D+++++K+ Q L++ H
Sbjct: 141 REIKILNRFK-HENIINIQEI-IRSETVDSLKDIYIVQCLMETDLYKLLKT-QKLSNDHV 197
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
F+YQIL GLKYIHSA+VLHRDLKP NLL+N C LKICDFGLAR ++ ++ FLT
Sbjct: 198 CYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VTDPQTDHTGFLT 256
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
EYVATRWYRAPEIML+ +GYTK+IDVWS GCILAE+L +P+F GK Y+DQLN IL V+G
Sbjct: 257 EYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVG 316
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
+P L+ I + + Y+ L + PK P++ LYP A+P AL+LL+ ML+F+P RI ++
Sbjct: 317 SPSNADLQCIINDKARSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIE 376
Query: 313 DALQHPYLSIWHDPADEPICTEKF--DFSFESVNEIEQLKQMVIDE 356
AL HPYL ++DP DEP+C E F + F+ + + E+LK+++ +E
Sbjct: 377 QALAHPYLEQYYDPGDEPVCEEPFTLEMEFDDLPK-EKLKELIWEE 421
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 307 bits (787), Expect = 2e-83
Identities = 167/346 (48%), Positives = 237/346 (68%), Gaps = 10/346 (2%)
Query: 13 KVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSL 72
+V Q F V R+ + IG G+YG+V SA T D VAIKK++ F C+R+L
Sbjct: 16 EVHGQLFEVAPRYVNLSYIGEGAYGMVASALDTITRDR--VAIKKISP-FEHQTFCQRTL 72
Query: 73 RELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
RE+K+L F+ H+NI + ++ I + +Y+ + LME D+++++K+ Q L++ H
Sbjct: 73 REIKILNRFK-HENIINIQEI-IRSETVDSLKDIYIVQCLMETDLYKLLKT-QKLSNDHV 129
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
F+YQIL GLKYIHSA+VLHRDLKP NLL+N C LKICDFGLAR ++ ++ FLT
Sbjct: 130 CYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VTDPQTDHTGFLT 188
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
EYVATRWYRAPEIML+ +GYTK+IDVWS GCILAE+L +P+F GK Y+DQLN IL V+G
Sbjct: 189 EYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVG 248
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
+P L+ I + + Y+ L + PK P++ LYP A+P AL+LL+ ML+F+P RI ++
Sbjct: 249 SPSNADLQCIINDKARSYLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIE 308
Query: 313 DALQHPYLSIWHDPADEPICTEKF--DFSFESVNEIEQLKQMVIDE 356
AL HPYL ++DP DEP+C E F + F+ + + E+LK+++ +E
Sbjct: 309 QALAHPYLEQYYDPGDEPVCEEPFTLEMEFDDLPK-EKLKELIWEE 353
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 304 bits (779), Expect = 2e-82
Identities = 162/349 (46%), Positives = 222/349 (63%), Gaps = 8/349 (2%)
Query: 9 RHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLC 68
+H + ++ F +D ++ IK IG G+YG+VCS+ E + VAIKK+ NVF +
Sbjct: 16 KHYYSMWQTLFEIDTKYVPIKPIGRGAYGVVCSSINRETNER--VAIKKIHNVFENRVDA 73
Query: 69 KRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLT 128
R+LRELKLLRH R H+N+ L D+ + F +YL ELM+ D+HQI+KS Q L+
Sbjct: 74 LRTLRELKLLRHVR-HENVIALKDVMLPANRSS-FKDVYLVYELMDTDLHQIIKSSQSLS 131
Query: 129 DAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENN 188
D H + F++Q+L GLKY+HSA++LHRDLKPGNLLVNA+C LKICDFGLAR N
Sbjct: 132 DDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLAR----TSQGNE 187
Query: 189 QFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRIL 248
QF+TEYV TRWYRAPE++L Y +IDVWS GCI AE+LG KPIF G + ++QL I+
Sbjct: 188 QFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLII 247
Query: 249 QVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLR 308
V+G+ E ++ I + + +I L Y S LYP ANP A++LL+ ML FDP R
Sbjct: 248 NVVGSQQESDIRFIDNPKARRFIKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKR 307
Query: 309 ITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEV 357
I+V DAL HPY++ DP P + E +++M+ +E+
Sbjct: 308 ISVTDALLHPYMAGLFDPGSNPPAHVPISLDIDENMEEPVIREMMWNEM 356
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 300 bits (768), Expect = 3e-81
Identities = 167/361 (46%), Positives = 229/361 (63%), Gaps = 26/361 (7%)
Query: 19 FTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLL 78
F + +++L+ IG G+YG VCSA + + VAIKK+ FSK L R++RE+KLL
Sbjct: 7 FDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIK--VAIKKI-QPFSKKLFVTRTIREIKLL 63
Query: 79 RHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP----LTDAHYQS 134
R+F H+NI + D D + N +YL EELME D+ +++ + L+D H Q
Sbjct: 64 RYFHEHENIISILDKVRPVSIDKL-NAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQY 122
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ---FL 191
F YQIL LK IHSA V+HRD+KP NLL+N++C LK+CDFGLAR + + F+
Sbjct: 123 FTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFM 182
Query: 192 TEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVL 251
TEYVATRWYRAPEIML++Q YT A+D+WSCGCILAE++ GKP+F G+DY QL IL+VL
Sbjct: 183 TEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVL 242
Query: 252 GTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLY--PNANPDALNLLEGMLSFDPQLRI 309
GTP E +I SK ++YI L P +P+ T++ + NPD ++LL+ ML F+P RI
Sbjct: 243 GTPSFEDFNQIKSKRAKEYIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRI 302
Query: 310 TVDDALQHPYLSIWHDPADEPICTE-KFDFSF------------ESVNEIEQLKQMVIDE 356
+ +AL+HPYL+++HDP+DEP D F E IE LK M+ DE
Sbjct: 303 SAAEALRHPYLAMYHDPSDEPEYPPLNLDDEFWKLDNKIMRPEEEEEVPIEMLKDMLYDE 362
Query: 357 V 357
+
Sbjct: 363 L 363
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 299 bits (766), Expect = 6e-81
Identities = 166/355 (46%), Positives = 229/355 (63%), Gaps = 16/355 (4%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V +R+Q + +G G+YG VC+A T+ VA+KK++ F + KR+ REL+LL+H
Sbjct: 20 VPERYQNLSPVGSGAYGSVCAAFDTKTG--LRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQIL 140
+ H+N+ L D+ + FN +YL LM D++ IVK Q LTD H Q IYQIL
Sbjct: 78 MK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQIL 135
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GLKYIHSAD++HRDLKP NL VN DC+LKI DFGLAR + +T YVATRWY
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWY 188
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEIML++ Y + +D+WS GCI+AELL G+ +F G D++DQL IL+++GTP E LK
Sbjct: 189 RAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLK 248
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
+I S++ ++YI L +PK+ F+ ++ ANP A++LLE ML D RIT AL H Y
Sbjct: 249 KISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF 308
Query: 321 SIWHDPADEPICTEKFDFSFESVN-EIEQLKQMVIDEVTDFRQYVRLPLLHEQQQ 374
+ +HDP DEP+ + +D SFES + I++ K + DEV F V PL E+ +
Sbjct: 309 AQYHDPDDEPV-ADPYDQSFESRDLLIDEWKSLTYDEVISF---VPPPLDQEEME 359
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 296 bits (759), Expect = 4e-80
Identities = 162/352 (46%), Positives = 225/352 (63%), Gaps = 16/352 (4%)
Query: 12 FKVFNQDFTVDKRF-QLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR 70
+ V+ F V ++ I+ IG G+ S ++ +AIKK+ F + KR
Sbjct: 29 YNVYGNLFEVSNKYVPPIRPIGRGA-----SVLSVDSETHEEIAIKKIGKAFDNKVDAKR 83
Query: 71 SLRELKLLRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTD 129
+LRE+KLLRH H+N+ + DI+ P F +Y+ ELM+ D+HQI++S Q L D
Sbjct: 84 TLREIKLLRHLE-HENVVVI--KDIIRPPKKEDFVDVYIVFELMDTDLHQIIRSNQSLND 140
Query: 130 AHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ 189
H Q F+YQIL GLKYIHSA+VLHRDLKP NLL+N++C LKI DFGLAR SE +
Sbjct: 141 DHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTTSET-----E 195
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
++TEYV TRWYRAPE++L+ YT AIDVWS GCI AE++ +P+F GKDYV QL I +
Sbjct: 196 YMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITE 255
Query: 250 VLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRI 309
++G+P +L+ + S N + Y+ +L P+ FS +P+ N A++LLE ML FDP RI
Sbjct: 256 LIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPSMNSTAIDLLEKMLVFDPVKRI 315
Query: 310 TVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEI-EQLKQMVIDEVTDF 360
TV++AL +PYLS HD DEP+C+ F F FE + E++K++V E F
Sbjct: 316 TVEEALCYPYLSALHDLNDEPVCSNHFSFHFEDPSSTEEEIKELVWLESVKF 367
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 295 bits (755), Expect = 1e-79
Identities = 160/357 (44%), Positives = 232/357 (64%), Gaps = 20/357 (5%)
Query: 9 RHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLC 68
+H + ++ F +D ++ IK IG G+YG+VCS+ +E + VAIKK+ NVF +
Sbjct: 16 KHYYTMWQTLFEIDTKYVPIKPIGRGAYGVVCSSINSETNER--VAIKKIHNVFENRIDA 73
Query: 69 KRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLT 128
R+LRELKLLRH R H+N+ L D+ + F +YL ELM+ D++QI+KS Q L+
Sbjct: 74 LRTLRELKLLRHVR-HENVISLKDVMLPTHRYS-FRDVYLVYELMDSDLNQIIKSSQSLS 131
Query: 129 DAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENN 188
D H + F++Q+L GLKY+HSA++LHRDLKPGNLLVNA+C LKICDFGLAR Y
Sbjct: 132 DDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTYE------- 184
Query: 189 QFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRIL 248
QF+TEYV TRWYRAPE++L Y +IDVWS GCI AE+LG KPIF G + ++QL I+
Sbjct: 185 QFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLII 244
Query: 249 QVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLR 308
V+G+ + L+ I ++ + +I L + FS +YP+ANP A++LL+ ML FDP R
Sbjct: 245 NVVGSQQDWDLQFIDNQKARRFIKSLPFSKGTHFSHIYPHANPLAIDLLQRMLVFDPTKR 304
Query: 309 ITVDDALQHPYLSIWHDP-----ADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDF 360
I+V DAL HPY+ +P + P+ + + D + E + +++M+ +E+ +
Sbjct: 305 ISVSDALLHPYMEGLLEPECNPSENVPVSSLEIDENMEG----DMIREMMWEEMLHY 357
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 294 bits (753), Expect = 2e-79
Identities = 160/352 (45%), Positives = 228/352 (64%), Gaps = 13/352 (3%)
Query: 12 FKVFNQDFTVDKRF-QLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR 70
+ V+ Q F V +++ I+ IG G+ GIVC+A + ++ VAIKK+ N F + KR
Sbjct: 61 YNVYGQLFEVSRKYVPPIRPIGRGACGIVCAAVNSVTGEK--VAIKKIGNAFDNIIDAKR 118
Query: 71 SLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDA 130
+LRE+KLLRH H+N+ + D+ Q D +FN +Y+ ELM+ D+ +I++S Q LT
Sbjct: 119 TLREIKLLRHM-DHENVITIKDIVRPPQRD-IFNDVYIVYELMDTDLQRILRSNQTLTSD 176
Query: 131 HYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQF 190
+ +YQ+L GLKY+HSA++LHRDL+P N+L+N+ +LKI DFGLAR S+ F
Sbjct: 177 QCRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDT-----DF 231
Query: 191 LTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQV 250
+TEYV TRWYRAPE++L+ YT AID+WS GCIL E++ G+P+F GKDYV QL I ++
Sbjct: 232 MTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITEL 291
Query: 251 LGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRIT 310
+G+P +L + S N + Y+ QL PK F+ +P A++LLE ML FDP RI+
Sbjct: 292 VGSPDNSSLGFLRSDNARRYVRQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRIS 351
Query: 311 VDDALQHPYLSIWHDPADEPICTEKFDFSFE--SVNEIEQLKQMVIDEVTDF 360
VD+AL H YLS HD A EP+C+ F F FE S E E +K+++ E F
Sbjct: 352 VDEALGHAYLSPHHDVAKEPVCSTPFSFDFEHPSCTE-EHIKELIYKESVKF 402
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 293 bits (750), Expect = 4e-79
Identities = 157/353 (44%), Positives = 227/353 (63%), Gaps = 22/353 (6%)
Query: 19 FTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLL 78
+ + FQL +G G+YG+VCSA T VAIKK+ F K L R+LRE+K+L
Sbjct: 7 YNISSDFQLKSLLGEGAYGVVCSA--THKPTGEIVAIKKI-EPFDKPLFALRTLREIKIL 63
Query: 79 RHFRGHKNITCLYDMDIVFQPDGM--FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFI 136
+HF+ H+NI ++++ +PD FN +Y+ +ELM+ D+H+++ S Q L+D H Q FI
Sbjct: 64 KHFK-HENIITIFNIQ---RPDSFENFNEVYIIQELMQTDLHRVI-STQMLSDDHIQYFI 118
Query: 137 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ------F 190
YQ L +K +H ++V+HRDLKP NLL+N++C LK+CDFGLAR E+ +N++
Sbjct: 119 YQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSG 178
Query: 191 LTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQV 250
+TEYVATRWYRAPE+ML+ Y++A+DVWSCGCILAEL +PIF G+DY QL I +
Sbjct: 179 MTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGI 238
Query: 251 LGTP-PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRI 309
+GTP + L+ I S ++YI L P P ++P NP ++LL+ ML FDP RI
Sbjct: 239 IGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRI 298
Query: 310 TVDDALQHPYLSIWHDPAD----EPICTEKFDFS-FESVNEIEQLKQMVIDEV 357
T +AL+HPYL +HDP D EPI F+F ++ + LK+++ +E+
Sbjct: 299 TAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHYKEALTTKDLKKLIWNEI 351
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 293 bits (750), Expect = 4e-79
Identities = 162/355 (45%), Positives = 226/355 (63%), Gaps = 16/355 (4%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V +R+Q + +G G+YG VC+A T+ VA+KK++ F + KR+ REL+LL+H
Sbjct: 20 VPERYQNLSPVGSGAYGSVCAAFDTKTG--LRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQIL 140
+ H+N+ L D+ + FN +YL LM D++ IVK Q LTD H Q IYQIL
Sbjct: 78 MK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQIL 135
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GLKYIHSAD++HRDLKP NL VN DC+LKI DFGLAR + +T YVATRWY
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWY 188
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEIML++ Y + +D+WS GCI+AELL G+ +F G D+++QL +I+++ GTPP +
Sbjct: 189 RAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLIN 248
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
R+ S ++YI L +PK+ F+ ++ ANP A++LLE ML D RIT AL H Y
Sbjct: 249 RMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF 308
Query: 321 SIWHDPADEPICTEKFDFSFESVN-EIEQLKQMVIDEVTDFRQYVRLPLLHEQQQ 374
+ +HDP DEP+ + +D SFES + I++ K + DEV F V PL E+ +
Sbjct: 309 AQYHDPDDEPV-ADPYDQSFESRDLLIDEWKSLTYDEVISF---VPPPLDQEEME 359
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 290 bits (741), Expect = 4e-78
Identities = 158/349 (45%), Positives = 223/349 (63%), Gaps = 18/349 (5%)
Query: 18 DFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKL 77
++ + + +Q ++ +G G+YG VC A T VAIKK+ F + KR+ REL+L
Sbjct: 17 EWEIPETYQNLQPVGQGAYGQVCKA--VVRGTSTKVAIKKLARPFQSAVHAKRTYRELRL 74
Query: 78 LRHFRGHKNITCLYDMDIVFQPDG---MFNGLYLYEELMECDMHQIVKSGQPLTDAHYQS 134
L+H H+N+ L D+ QP F +Y+ LM+ D++ I+++ Q L+D H Q
Sbjct: 75 LKHM-DHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRT-QKLSDDHVQF 132
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
+YQIL GLKYIHSA V+HRDLKP N+ VN DC+L+I DFGLAR P E+ +T Y
Sbjct: 133 LVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR-----PAESE--MTGY 185
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
VATRWYRAPEIML++ Y + D+WS GCI+AELL G+ +F G D++ QLN I++VLGTP
Sbjct: 186 VATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTP 245
Query: 255 PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDA 314
+E + RI S++ ++YI L +P+ F ++ ANP A++LLE ML D RIT + A
Sbjct: 246 ADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQA 305
Query: 315 LQHPYLSIWHDPADEPICTEKFDFSFESVNE--IEQLKQMVIDEVTDFR 361
L HPY+ +HDP DE +D SFE NE +E+ ++MV EVT F+
Sbjct: 306 LAHPYMEKYHDPTDEQTAA-LYDQSFEE-NELPVEKWREMVFSEVTAFK 352
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 286 bits (733), Expect = 4e-77
Identities = 159/348 (45%), Positives = 216/348 (61%), Gaps = 17/348 (4%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
IG G+YG VC+A T + T VAIKK F + +R+ REL+LLR H+NI L
Sbjct: 41 IGTGAYGTVCAAECTRSG--TRVAIKKFNRPFQSIIHARRTYRELRLLRCMC-HENIIDL 97
Query: 91 YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIH 147
D VF P+ N + Y LM D+ I+K Q L D H Q +YQIL GLKYIH
Sbjct: 98 LD---VFTPNENVNDIEDVYFVSMLMGADLSNILKI-QRLNDDHIQFLVYQILRGLKYIH 153
Query: 148 SADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIML 207
SAD++HRDLKP N+ VN DC+LKI DFGLAR + + +T YVATRWYRAPEIML
Sbjct: 154 SADIIHRDLKPSNIAVNEDCELKILDFGLAR-------QTDSEMTGYVATRWYRAPEIML 206
Query: 208 SYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKNV 267
++ YT+ +DVWS GCILAEL+ GK +F G D++DQL RI+ V GTP EE LK+I S+
Sbjct: 207 NWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEA 266
Query: 268 QDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPA 327
++YI L + + F L+ A P A++LLE ML DP R T +A++H YL+ +HD
Sbjct: 267 RNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYLAAYHDET 326
Query: 328 DEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPLLHEQQQQ 375
DEPI E + I++ K+++ +E++DF++ V E +++
Sbjct: 327 DEPIAEEMDLNDDVRADTIDEWKKIIWEEISDFQKNVAFADEEEDEEK 374
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 286 bits (732), Expect = 5e-77
Identities = 169/404 (41%), Positives = 245/404 (59%), Gaps = 20/404 (4%)
Query: 15 FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
F D+ RF++ + IG GSYG+VCSA T ++ VAIKK+ ++F R LRE
Sbjct: 3 FFSDYGDANRFKVQEVIGKGSYGVVCSAIDTLTGEK--VAIKKIHDIFEHISDAARILRE 60
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQ 133
+KLLR R H +I + I+ P F +Y+ ELME D+HQ++K+ LT HYQ
Sbjct: 61 IKLLRLLR-HPDIVEI--KHIMLPPSRREFKDIYVVFELMESDLHQVIKANDDLTREHYQ 117
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
F+YQ+L LKYIH+A+V HRDLKP N+L NA+C+LKICDFGLAR + N F T+
Sbjct: 118 FFLYQLLRALKYIHTANVYHRDLKPKNILANANCKLKICDFGLAR-VAFNDTPTTIFWTD 176
Query: 194 YVATRWYRAPEIMLS-YQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
YVATRWYRAPE+ S Y YT AID+WS GCI AE+L GKP+F GK+ V QL+ + +LG
Sbjct: 177 YVATRWYRAPELCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLG 236
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
TP +T+ R+ ++ + Y+ + P IPF+ +PNA+P +L LLE +L+FDP+ R T +
Sbjct: 237 TPSLDTISRVRNEKARRYLTSMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAE 296
Query: 313 DALQHPYL----SIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPL 368
+AL PY + +P+ +PI +F+F V + E +++++ E+ ++ L
Sbjct: 297 EALADPYFKGLAKVEREPSCQPITKMEFEFERRKVTK-EDIRELISREILEYHP----QL 351
Query: 369 LHEQQQQQGKTDGGFDDQIREDQRTFQAQLEEQVNNGRTASNVP 412
L + K + + + +R F A LEE N+G+T P
Sbjct: 352 LKDHMNGADKASFLYPSAVDQFRRQF-AHLEE--NSGKTGPVAP 392
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 283 bits (725), Expect = 3e-76
Identities = 168/413 (40%), Positives = 246/413 (58%), Gaps = 22/413 (5%)
Query: 4 YDAVDRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFS 63
Y +D H K F ++ R+Q+ + IG GSYG+V SA T + ++ VAIKK+ +VF
Sbjct: 107 YILMDPH--KKFFTEYGEASRYQIQEVIGKGSYGVVASAIDTHSGEK--VAIKKINDVFE 162
Query: 64 KTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM--FNGLYLYEELMECDMHQIV 121
R LRE+KLLR R H +I ++ V P F +Y+ ELME D+HQ++
Sbjct: 163 HVSDATRILREIKLLRLLR-HPDIV---EIKHVMLPPSRREFRDIYVVFELMESDLHQVI 218
Query: 122 KSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYS 181
K+ LT HYQ F+YQ+L GLK+IH+A+V HRDLKP N+L N+DC+LKICDFGLAR S
Sbjct: 219 KANDDLTPEHYQFFLYQLLRGLKFIHTANVFHRDLKPKNILANSDCKLKICDFGLAR-VS 277
Query: 182 ENPVENNQFLTEYVATRWYRAPEIMLS-YQGYTKAIDVWSCGCILAELLGGKPIFKGKDY 240
N + F T+YVATRWYRAPE+ S + YT AID+WS GCI AE+L GKP+F GK+
Sbjct: 278 FNDAPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNV 337
Query: 241 VDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGM 300
V QL+ + +LGTPP E + RI ++ + Y+ + P +PF+ +P+ +P AL LL +
Sbjct: 338 VHQLDIMTDLLGTPPPEAIARIRNEKARRYLGNMRRKPPVPFTHKFPHVDPLALRLLHRL 397
Query: 301 LSFDPQLRITVDDALQHPYL----SIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDE 356
L+FDP+ R + ++AL PY ++ +P+ +PI +F+F + + E +++++ E
Sbjct: 398 LAFDPKDRPSAEEALADPYFYGLANVDREPSTQPIPKLEFEFERRKITK-EDVRELIYRE 456
Query: 357 VTDFRQYVRLPLLHEQQQQQGKTDGGFDDQIREDQRTFQAQLEEQVNNGRTAS 409
+ ++ + L +Q G D +R F A LEE G S
Sbjct: 457 ILEYHPQMLQEYLRGGEQTSFMYPSGVD----RFKRQF-AHLEENYGKGEKGS 504
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 283 bits (724), Expect = 4e-76
Identities = 153/342 (44%), Positives = 217/342 (62%), Gaps = 13/342 (3%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V +R Q ++ +G G+YG VCSA +A VA+KK++ F + +R+ REL+LL+H
Sbjct: 20 VPQRLQGLRPVGSGAYGSVCSAY--DARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKH 77
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQIL 140
+ H+N+ L D+ F+ +YL LM D++ IVK Q L+D H Q +YQ+L
Sbjct: 78 LK-HENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKC-QALSDEHVQFLVYQLL 135
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GLKYIHSA ++HRDLKP N+ VN DC+L+I DFGLAR E +T YVATRWY
Sbjct: 136 RGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEE-------MTGYVATRWY 188
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEIML++ Y + +D+WS GCI+AELL GK +F G DY+DQL RI++V+GTP E L
Sbjct: 189 RAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLA 248
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
+I S++ + YI L +P+ S+++ ANP A++LL ML D R++ +AL H Y
Sbjct: 249 KISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYF 308
Query: 321 SIWHDPADEPICTEKFDFSFESVNE-IEQLKQMVIDEVTDFR 361
S +HDP DEP E +D S E+ +E+ K++ EV F+
Sbjct: 309 SQYHDPEDEPE-AEPYDESVEAKERTLEEWKELTYQEVLSFK 349
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 280 bits (717), Expect = 3e-75
Identities = 166/404 (41%), Positives = 241/404 (59%), Gaps = 19/404 (4%)
Query: 15 FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
F ++ R+++ + IG GSYG+VCSA T ++ VAIKK+ ++F R LRE
Sbjct: 15 FFTEYGEGSRYRIEEVIGKGSYGVVCSAYDTHTGEK--VAIKKINDIFEHVSDATRILRE 72
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQ 133
+KLLR R H +I + I+ P F +Y+ ELME D+HQ++K+ LT HYQ
Sbjct: 73 IKLLRLLR-HPDIVEI--KHILLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQ 129
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
F+YQ+L GLKYIH+A+V HRDLKP N+L NADC+LKICDFGLAR + N F T+
Sbjct: 130 FFLYQLLRGLKYIHTANVFHRDLKPKNILANADCKLKICDFGLAR-VAFNDTPTAIFWTD 188
Query: 194 YVATRWYRAPEIMLS-YQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
YVATRWYRAPE+ S + YT AID+WS GCI AELL GKP+F GK+ V QL+ + +LG
Sbjct: 189 YVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLG 248
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
TP E + R+ ++ + Y+ + IPFS +P+ +P AL LLE MLSF+P+ R T +
Sbjct: 249 TPSAEAIGRVRNEKARRYLSSMRKKKPIPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAE 308
Query: 313 DALQHPYL----SIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPL 368
+AL Y + +P+ +P+ +F+F + + E +++++ E ++ +
Sbjct: 309 EALADVYFKGLAKVEREPSAQPVTKLEFEFERRRITK-EDVRELIYRESLEYHP----KM 363
Query: 369 LHEQQQQQGKTDGGFDDQIREDQRTFQAQLEEQVNNGRTASNVP 412
L E T+ + + ++ F A LEE NG T+ N P
Sbjct: 364 LKEYLDGSEPTNFMYPSAVEHFKKQF-AYLEEHYKNG-TSHNPP 405
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 278 bits (712), Expect = 1e-74
Identities = 154/352 (43%), Positives = 222/352 (62%), Gaps = 13/352 (3%)
Query: 15 FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
F ++ R+Q+ + +G GSYG+V SA + + VAIKK+ +VF R LRE
Sbjct: 94 FFTEYGEANRYQIQEVVGKGSYGVVASAVDSHTGER--VAIKKINDVFEHVSDATRILRE 151
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQ 133
+KLLR R H ++ + I+ P F +Y+ ELME D+HQ++K+ LT HYQ
Sbjct: 152 IKLLRLLR-HPDVVEI--KHIMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQ 208
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
F+YQ+L GLKY+H+A+V HRDLKP N+L NADC+LKICDFGLAR S N F T+
Sbjct: 209 FFLYQLLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLAR-VSFNDAPTAIFWTD 267
Query: 194 YVATRWYRAPEIMLSY-QGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
YVATRWYRAPE+ S+ YT AID+WS GCI AE+L GKP+F GK+ V QL+ + LG
Sbjct: 268 YVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLG 327
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
TPP E++ RI ++ + Y+ + +PFS +P A+P AL LLE +L+FDP+ R + +
Sbjct: 328 TPPPESISRIRNEKARRYLSSMRKKQPVPFSHKFPKADPLALRLLERLLAFDPKDRASAE 387
Query: 313 DALQHPYLS----IWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDF 360
DAL PY S +P +PI +FDF + + + + +++++ E+ ++
Sbjct: 388 DALADPYFSGLSNSEREPTTQPISKLEFDFERKKLVK-DDVRELIYREILEY 438
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 275 bits (703), Expect = 1e-73
Identities = 174/453 (38%), Positives = 266/453 (58%), Gaps = 37/453 (8%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+++++ IG GSYG+VC+A T+ ++ VAIKK+ +VF R LRE+KLLR R
Sbjct: 12 RYRILEVIGKGSYGVVCAAIDTQTGEK--VAIKKINDVFEHVSDALRILREVKLLRLLR- 68
Query: 84 HKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
H +I + I+ P F +Y+ ELME D+HQ++K+ LT H+Q F+YQ+L
Sbjct: 69 HPDIVEI--KSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRA 126
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
LKY+H+A+V HRDLKP N+L NA+C+LK+CDFGLAR S N F T+YVATRWYRA
Sbjct: 127 LKYMHTANVYHRDLKPKNILANANCKLKVCDFGLAR-VSFNDTPTTVFWTDYVATRWYRA 185
Query: 203 PEIMLSY-QGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
PE+ S+ YT AID+WS GCI AE+L GKP+F GK V QL+ I +LGTP ET+
Sbjct: 186 PELCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETIAG 245
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL- 320
+ ++ + Y++++ +PFS +PNA+P AL LL+ +L+FDP+ R T +AL PY
Sbjct: 246 VRNEKARKYLNEMRKKNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEALADPYFK 305
Query: 321 ---SIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPLLHEQQQQQG 377
+ +P+ +PI +F+F + + + +++++ E+ ++ LL + +G
Sbjct: 306 CLAKVEREPSCQPISKMEFEFERRRLTK-DDIRELIYREILEYHP----QLLKDYMNSEG 360
Query: 378 KTDGGFDDQIREDQRTFQAQLEEQVNNGRTASNVPSFDEPFSSQMMGSASQQDPLVGIHS 437
+ + I ++ F A LEE N+G++ +P D +S P +HS
Sbjct: 361 -SSFLYPSAIGHLRKQF-AYLEE--NSGKSGPVIPP-DRKHASL---------PRSAVHS 406
Query: 438 DNLPSHELDFPPRPSENVLDSPMGLSHQQTHNG 470
+ S+ +PS N DS +S + + NG
Sbjct: 407 SAVNSN-----AQPSLNASDS-RRVSIEPSRNG 433
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 274 bits (701), Expect = 2e-73
Identities = 135/277 (48%), Positives = 187/277 (66%), Gaps = 4/277 (1%)
Query: 113 MECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKIC 172
ME D+HQI+ S QPLT H + F+YQ+L GLKY+HSA V+HRDLKP NLLVN +C+LKI
Sbjct: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
Query: 173 DFGLARGYSENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGK 232
DFG+ARG +P E+ F+TEYVATRWYRAPE+MLS YT+AID+WS GCI E+L +
Sbjct: 61 DFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARR 120
Query: 233 PIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPD 292
+F GK+YV QL I+ VLGTP ++ +G++ V+ YI L +P+ T+YP A+
Sbjct: 121 QLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQ 180
Query: 293 ALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPADEPICTEKFDFSFE-SVNEIEQLKQ 351
AL+LL ML F+P RI+ AL+HP+L+ +HDP DEP C FDF+F+ E++K+
Sbjct: 181 ALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERIKE 240
Query: 352 MVIDEVTDF---RQYVRLPLLHEQQQQQGKTDGGFDD 385
++ E+ DF R+ +R + + Q ++ G D
Sbjct: 241 AIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPD 277
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 274 bits (700), Expect = 3e-73
Identities = 150/341 (43%), Positives = 218/341 (62%), Gaps = 16/341 (4%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+Q ++ +G G+YG V A VAIKK+ F + KR+ REL+LL+H H
Sbjct: 25 YQDLQPVGSGAYGQVSKA--VVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHM-DH 81
Query: 85 KNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILC 141
+N+ L D+ +G F +YL LM+ D++ I++ Q L+D H Q +YQIL
Sbjct: 82 ENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRM-QHLSDDHVQFLVYQILR 140
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
GLKYIHSA V+HRDLKP N+ VN DC+L+I DFGLAR P EN +T YVATRWYR
Sbjct: 141 GLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR-----PTENE--MTGYVATRWYR 193
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APEIML++ Y + +D+WS GCI+AEL+ + +F G D++ QLN I+++LGTPP E LK+
Sbjct: 194 APEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKK 253
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
I S++ + YI L + F ++ NANP A++LLE ML D + RIT ++AL HPYL
Sbjct: 254 ISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLE 313
Query: 322 IWHDPADEPICTEKFDFSFESVN-EIEQLKQMVIDEVTDFR 361
+ +P+ E + +D SFE ++ +++ K+++ EVT+F+
Sbjct: 314 KYAEPSVEQ-TSPPYDHSFEDMDLPVDKWKELIYKEVTNFK 353
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 270 bits (689), Expect = 5e-72
Identities = 159/399 (39%), Positives = 233/399 (57%), Gaps = 17/399 (4%)
Query: 15 FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
F ++ R+Q+ + +G GSYG+V SA T + VAIKK+ +VF R LRE
Sbjct: 80 FFTEYGEANRYQIQEVVGKGSYGVVGSAIDTHTGER--VAIKKINDVFDHISDATRILRE 137
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQ 133
+KLLR H ++ + I+ P F +Y+ ELME D+HQ++K+ LT H+Q
Sbjct: 138 IKLLRLLL-HPDVVEI--KHIMLPPSRREFRDVYVVFELMESDLHQVIKANDDLTPEHHQ 194
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
F+YQ+L GLKY+H+A+V HRDLKP N+L NADC+LKICDFGLAR S N F T+
Sbjct: 195 FFLYQLLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLAR-VSFNDAPTAIFWTD 253
Query: 194 YVATRWYRAPEIMLS-YQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
YVATRWYRAPE+ S + YT AID+WS GCI AE+L GKP+F GK+ V QL+ + LG
Sbjct: 254 YVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLG 313
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
TPP E + +I + + Y+ + +PFS +P A+P AL LLE +++FDP+ R + +
Sbjct: 314 TPPPEAISKIRNDKARRYLGNMRKKQPVPFSKKFPKADPSALRLLERLIAFDPKDRPSAE 373
Query: 313 DALQHPYL----SIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPL 368
+AL PY S +P+ +PI +F+F + + + + +++++ E+ ++ +
Sbjct: 374 EALADPYFNGLSSKVREPSTQPISKLEFEFERKKLTK-DDIRELIYREILEYHPQMLEEY 432
Query: 369 LHEQQQQQGKTDGGFDDQIREDQRTFQAQLEEQVNNGRT 407
L Q G D +R F E Q GR+
Sbjct: 433 LRGGNQLSFMYPSGVD----RFRRQFAHLEENQGPGGRS 467
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 269 bits (688), Expect = 6e-72
Identities = 146/338 (43%), Positives = 213/338 (62%), Gaps = 19/338 (5%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
++ +G G+YG VCSA + VAIKK+ F L KR+ REL+LL+H R H+N+
Sbjct: 30 LQPVGSGAYGAVCSA--VDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMR-HENV 86
Query: 88 TCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
L D VF PD F YL M D+ +++K + L + Q +YQ+L GL+
Sbjct: 87 IGLLD---VFTPDETLDDFTDFYLVMPFMGTDLGKLMKH-EKLGEDRIQFLVYQMLKGLR 142
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
YIH+A ++HRDLKPGNL VN DC+LKI DFGLAR + + +T YV TRWYRAPE
Sbjct: 143 YIHAAGIIHRDLKPGNLAVNEDCELKILDFGLAR-------QADSEMTGYVVTRWYRAPE 195
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++L++ YT+ +D+WS GCI+AE++ GK +FKG D++DQL I++V GTPP E ++R+ S
Sbjct: 196 VILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQS 255
Query: 265 KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWH 324
++ + L + K F+++ NA+P A+NLLE ML D + R+T +AL HPY H
Sbjct: 256 DEAKNNMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESLH 315
Query: 325 DPADEPICTEKFDFSFESVNE-IEQLKQMVIDEVTDFR 361
D DEP +K+D SF+ V+ +++ K++ EV F+
Sbjct: 316 DTEDEP-QVQKYDDSFDDVDRTLDEWKRVTYKEVLSFK 352
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 267 bits (683), Expect = 2e-71
Identities = 137/310 (44%), Positives = 195/310 (62%), Gaps = 12/310 (3%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+ +G G+YG+VC A T ++ VAIKK+ F+ L KRSLRE+++LR H+NI
Sbjct: 61 ENVGAGAYGVVCKAMDTR--NKKQVAIKKIPRAFTAHTLAKRSLREVRILRELL-HENII 117
Query: 89 CLYDMDIVFQPDGMFN-GLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIH 147
+ DM F +G +YL +LME D+HQI+ S Q L + H+Q F YQ+L GLKY+H
Sbjct: 118 AVLDM---FTAEGAHGKDIYLVMDLMETDLHQILHSRQTLMEQHFQYFFYQLLRGLKYLH 174
Query: 148 SADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ-----FLTEYVATRWYRA 202
SA ++HRDLKP NLL+N DC L+I DFG+AR Y+ + +T+YV+TRWYRA
Sbjct: 175 SAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVSTRWYRA 234
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PEI+ S Y +D+WS GCI AE+L + +F GKD V Q+ I+ LG+P EE + RI
Sbjct: 235 PEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEEEVINRI 294
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
S V+D I G +PFS ++P A+P+A N++ +L P R + D LQHP+++
Sbjct: 295 TSDLVRDSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQILQHPFMAQ 354
Query: 323 WHDPADEPIC 332
+H+ EP+C
Sbjct: 355 YHNDQYEPLC 364
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 266 bits (680), Expect = 5e-71
Identities = 146/339 (43%), Positives = 203/339 (59%), Gaps = 19/339 (5%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+G G+YG VCSA + ++ VAIKK++ F + KR+ REL LL+H + H+N+ L
Sbjct: 31 VGSGAYGSVCSAIDKRSGEK--VAIKKLSRPFQSEIFAKRAYRELLLLKHMQ-HENVIGL 87
Query: 91 YDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIH 147
D VF P F YL M+ D+ +I+ G ++ Q +YQ+L GLKYIH
Sbjct: 88 LD---VFTPASSLRNFYDFYLVMPFMQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIH 142
Query: 148 SADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIML 207
SA V+HRDLKPGNL VN DC+LKI DFGLAR +T YV TRWYRAPE++L
Sbjct: 143 SAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAE-------MTGYVVTRWYRAPEVIL 195
Query: 208 SYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKNV 267
S+ Y + +D+WS GCI+AE+L GK +FKGKDY+DQL +IL+V G P E ++++ K
Sbjct: 196 SWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAA 255
Query: 268 QDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPA 327
+ YI L P+ F+ L+P A+P A +LLE ML D R+T AL HP+ + DP
Sbjct: 256 KSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPE 315
Query: 328 DEPICTEKFDFSFESVN-EIEQLKQMVIDEVTDFRQYVR 365
+E + FD S E +++ KQ + E+ +F R
Sbjct: 316 EETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIAR 354
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 261 bits (667), Expect = 2e-69
Identities = 148/336 (44%), Positives = 212/336 (63%), Gaps = 16/336 (4%)
Query: 13 KVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSL 72
K F ++ ++Q+ + +G GSYG+V SA + VAIKK+TNVF R L
Sbjct: 4 KEFFTEYGEASQYQIQEVVGKGSYGVVASAECPHTGGK--VAIKKMTNVFEHVSDAIRIL 61
Query: 73 RELKLLRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAH 131
RE+KLLR R H +I + I+ P F +Y+ ELME D+H ++K LT H
Sbjct: 62 REIKLLRLLR-HPDIVEI--KHIMLPPCRKEFKDIYVVFELMESDLHHVLKVNDDLTPQH 118
Query: 132 YQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR-GYSENPVENNQF 190
+Q F+YQ+L GLK++HSA V HRDLKP N+L NADC++KICD GLAR ++++P + F
Sbjct: 119 HQFFLYQLLRGLKFMHSAHVFHRDLKPKNILANADCKIKICDLGLARVSFTDSP--SAVF 176
Query: 191 LTEYVATRWYRAPEIMLS-YQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
T+YVATRWYRAPE+ S Y YT AID+WS GCI AE+L GKP+F GK+ V QL +
Sbjct: 177 WTDYVATRWYRAPELCGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTD 236
Query: 250 VLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRI 309
+LGTP TL RI ++ + Y+ + +PF+ +PN +P AL LL+ +++FDP+ R
Sbjct: 237 LLGTPSPITLSRIRNEKARKYLGNMRRKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRP 296
Query: 310 TVDDALQHPYL----SIWHDPADEPICTEKFDFSFE 341
+ ++AL PY ++ ++P+ +PI K +F FE
Sbjct: 297 SAEEALADPYFQGLANVDYEPSRQPI--SKLEFEFE 330
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 258 bits (659), Expect = 1e-68
Identities = 144/343 (41%), Positives = 214/343 (61%), Gaps = 13/343 (3%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+++++ IG GSYG+VC+A T ++ VAIKK+ +VF R LRE+KLLR R
Sbjct: 12 RYRILEVIGKGSYGVVCAAIDTHTGEK--VAIKKINDVFEHISDALRILREVKLLRLLR- 68
Query: 84 HKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
H +I + I+ P F +Y+ ELME D+HQ++K+ LT H+Q F+YQ+L
Sbjct: 69 HPDIVEI--KSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRA 126
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
LK++H+A+V HRDLKP N+L NA+C+LK+CDFGLAR + N F T+YVATRWYRA
Sbjct: 127 LKFMHTANVYHRDLKPKNILANANCKLKVCDFGLAR-VAFNDTPTTVFWTDYVATRWYRA 185
Query: 203 PEIMLS-YQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
PE+ S + YT AIDVWS GCI AE+L GKP+F GK V QL I +LGTP ET+
Sbjct: 186 PELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETISG 245
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL- 320
+ + + Y+ ++ + FS + A+P AL LL+ +L+FDP+ R T +AL PY
Sbjct: 246 VRNDKARKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADPYFK 305
Query: 321 ---SIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDF 360
I +P+ + I +F+F + + + +++++ E+ ++
Sbjct: 306 GLSKIEREPSSQQISKMEFEFERRRLTK-DDIRELIYREILEY 347
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 251 bits (640), Expect = 2e-66
Identities = 131/271 (48%), Positives = 181/271 (66%), Gaps = 11/271 (4%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V +R+Q + +G G+YG VC+A T+ VA+KK++ F + KR+ REL+LL+H
Sbjct: 20 VPERYQNLSPVGSGAYGSVCAAFDTKTG--LRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQIL 140
+ H+N+ L D+ + FN +YL LM D++ IVK Q LTD H Q IYQIL
Sbjct: 78 MK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQIL 135
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GLKYIHSAD++HRDLKP NL VN DC+LKI DFGLAR + +T YVATRWY
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWY 188
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEIML++ Y + +D+WS GCI+AELL G+ +F G D++DQL IL+++GTP E LK
Sbjct: 189 RAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLK 248
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANP 291
+I S++ ++YI L +PK+ F+ ++ ANP
Sbjct: 249 KISSESARNYIQSLTQMPKMNFANVFIGANP 279
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 248 bits (634), Expect = 1e-65
Identities = 147/384 (38%), Positives = 224/384 (58%), Gaps = 32/384 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A T VA+KK++ F K
Sbjct: 11 YSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLG--INVAVKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL LL+ HKNI L + VF P F +YL ELM+ ++ Q++
Sbjct: 69 RAYRELVLLKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIH--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAC 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
N +T YV TR+YRAPE++L GY + +D+WS GCI+AE++ K +F G+DY+DQ N+
Sbjct: 178 TNFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPN------------ANPDAL 294
+++ LGTP E +K++ V++Y+ P I F L+P+ A
Sbjct: 237 VIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSFES-VNEIEQLKQM 352
+LL ML DP RI+VD+AL+HPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 296 DLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQQQQQ 376
+ EV D+ + + ++ +Q Q
Sbjct: 356 IYKEVMDWEERSKNGVVKDQPSAQ 379
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 248 bits (633), Expect = 1e-65
Identities = 152/388 (39%), Positives = 207/388 (53%), Gaps = 63/388 (16%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
H ++ + + + + +K +G G+YG+VC+A + D VAIKK F T+ K
Sbjct: 34 HEVELNKTKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDR--VAIKKFFRPFQSTIHAK 91
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPD---GMFNGLYLYEELMECDMHQIVKSGQP 126
R+ RELKLLR + H N+ + D VF PD N +Y LM D+ I+K Q
Sbjct: 92 RTYRELKLLRTLQ-HDNVLEMID---VFTPDPDASSLNNVYFVSVLMGSDLQNIMKI-QR 146
Query: 127 LTDAHYQSFIYQILCGLKY-----------------------------IHSADVLHRDLK 157
LTD Q IYQ+L GLKY IHSA ++HRDLK
Sbjct: 147 LTDEQIQLLIYQVLRGLKYMSHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLK 206
Query: 158 PGNLLVNADCQLK-----------------ICDFGLARGYSENPVENNQFLTEYVATRWY 200
P N+ VN C++K I DFGLAR +T YVATRWY
Sbjct: 207 PSNIAVNERCEVKVFLSFSQLSFLILSFFKILDFGLARAQDAE-------MTGYVATRWY 259
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEIML++ YT+ +DVWS GCILAEL+ G+P+F G D++DQL +I+ V+GTP EE
Sbjct: 260 RAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWS 319
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
+I S+ ++YI I + F TL+P A+P AL LLE ML DP RI+V AL+H YL
Sbjct: 320 KIQSEEARNYIKNRSPIIRQDFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDYL 379
Query: 321 SIWHDPADEPICTEKFDFSFESVNEIEQ 348
+ P DEP+ + S +++ E+
Sbjct: 380 REYSVPNDEPVAMDTVINSIVTIDPAEE 407
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 247 bits (631), Expect = 3e-65
Identities = 146/380 (38%), Positives = 223/380 (58%), Gaps = 32/380 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A T VA+KK++ F K
Sbjct: 11 YSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLG--INVAVKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL LL+ HKNI L + VF P F +YL ELM+ ++ Q++
Sbjct: 69 RAYRELVLLKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIH--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAC 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
N +T YV TR+YRAPE++L GY + +D+WS GCI+AE++ K +F G+DY+DQ N+
Sbjct: 178 TNFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPN------------ANPDAL 294
+++ LGTP E +K++ V++Y+ P I F L+P+ A
Sbjct: 237 VIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSFES-VNEIEQLKQM 352
+LL ML DP RI+VD+AL+HPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 296 DLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQ 372
+ EV D+ + + ++ +Q
Sbjct: 356 IYKEVMDWEERSKNGVVKDQ 375
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 247 bits (630), Expect = 3e-65
Identities = 147/384 (38%), Positives = 223/384 (57%), Gaps = 32/384 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A T VA+KK++ F K
Sbjct: 11 YSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLG--INVAVKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL LL+ HKNI L + VF P F +YL ELM+ ++ Q++
Sbjct: 69 RAYRELVLLKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIH--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAC 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
N +T YV TR+YRAPE++L GY + +D+WS GCI+ EL+ G IF+G D++DQ N+
Sbjct: 178 TNFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPN------------ANPDAL 294
+++ LGTP E +K++ V++Y+ P I F L+P+ A
Sbjct: 237 VIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSFES-VNEIEQLKQM 352
+LL ML DP RI+VD+AL+HPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 296 DLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQQQQQ 376
+ EV D+ + + ++ +Q Q
Sbjct: 356 IYKEVMDWEERSKNGVVKDQPSAQ 379
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 246 bits (627), Expect = 7e-65
Identities = 146/380 (38%), Positives = 222/380 (58%), Gaps = 32/380 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A T VA+KK++ F K
Sbjct: 11 YSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLG--INVAVKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL LL+ HKNI L + VF P F +YL ELM+ ++ Q++
Sbjct: 69 RAYRELVLLKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIH--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAC 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
N +T YV TR+YRAPE++L GY + +D+WS GCI+ EL+ G IF+G D++DQ N+
Sbjct: 178 TNFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPN------------ANPDAL 294
+++ LGTP E +K++ V++Y+ P I F L+P+ A
Sbjct: 237 VIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSFES-VNEIEQLKQM 352
+LL ML DP RI+VD+AL+HPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 296 DLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQ 372
+ EV D+ + + ++ +Q
Sbjct: 356 IYKEVMDWEERSKNGVVKDQ 375
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 246 bits (627), Expect = 7e-65
Identities = 146/380 (38%), Positives = 222/380 (58%), Gaps = 32/380 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A T VA+KK++ F K
Sbjct: 11 YSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLG--INVAVKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL LL+ HKNI L + VF P F +YL ELM+ ++ Q++
Sbjct: 69 RAYRELVLLKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIH--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAC 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
N +T YV TR+YRAPE++L GY + +D+WS GCI+ EL+ G IF+G D++DQ N+
Sbjct: 178 TNFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPN------------ANPDAL 294
+++ LGTP E +K++ V++Y+ P I F L+P+ A
Sbjct: 237 VIEQLGTPSAEFMKKL-QPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSFES-VNEIEQLKQM 352
+LL ML DP RI+VD+AL+HPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 296 DLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQ 372
+ EV D+ + + ++ +Q
Sbjct: 356 IYKEVMDWEERSKNGVVKDQ 375
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 244 bits (624), Expect = 2e-64
Identities = 145/375 (38%), Positives = 218/375 (57%), Gaps = 33/375 (8%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+ IG+G++G+V S T+ D VA+KK+ NVF + CKR RELK+L F+ H N+
Sbjct: 130 RPIGYGAFGVVWSV--TDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDNVL 186
Query: 89 CLYDMDIVFQPDGM--FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYI 146
D + QP + F +Y+ ELM+ D+H+I+ S QPL+ H + F+YQIL GLKY+
Sbjct: 187 SALD---ILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYL 243
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
HSA +LHRD+KPGNLLVN++C LKICDFGLAR ++ ++ +T+ V T++YRAPEI+
Sbjct: 244 HSAGILHRDIKPGNLLVNSNCVLKICDFGLAR---VEELDESRHMTQEVVTQYYRAPEIL 300
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKN 266
+ + Y+ AID+WS GCI AELLG + +F+ + + QL+ I +LGTP E ++
Sbjct: 301 MGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGA 360
Query: 267 VQDYIHQLGYIPKIP-FSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW-- 323
+ P +P TL A +A++LL ML FDP RI+ DAL HPYL
Sbjct: 361 KAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRL 420
Query: 324 ------------------HDPADEPICTEKFDFSFE-SVNEIEQLKQMVIDEVTDFRQYV 364
+ EP+ KFD +FE +++ + Q+K+++ + + ++
Sbjct: 421 RYHTCMCKCCFSTSTGRVYTSDFEPVTNPKFDDTFEKNLSSVRQVKEIIHQFILEQQKGN 480
Query: 365 RLPLLHEQQQQQGKT 379
R+PL Q K+
Sbjct: 481 RVPLCINPQSAAFKS 495
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 243 bits (619), Expect = 6e-64
Identities = 124/300 (41%), Positives = 186/300 (61%), Gaps = 13/300 (4%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+ +G G++G+VC A ++ VAIKK+T VF K +LRE+++ R H+NI
Sbjct: 48 ENLGAGAFGVVCRA--IDSKLNKQVAIKKITRVFKNQSTAKCALREIRITREL-SHENI- 103
Query: 89 CLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIHS 148
+ D++ + G +Y+ +LME D+ ++KS Q L + H+Q F YQIL GLKY+HS
Sbjct: 104 -INSTDVLMRESGSGQDIYIVMDLMETDLLSVLKSNQTLNEKHFQYFFYQILKGLKYLHS 162
Query: 149 ADVLHRDLKPGNLLVNADCQLKICDFGLAR-GYSENPVENNQ-------FLTEYVATRWY 200
A ++HRDLKP NLL+N DC LKI DFG++R G S N L++YV+T WY
Sbjct: 163 AGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVSTLWY 222
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEI+LS Y +D+WS GCILAE+L +PIF G D Q+ +++ LGTP E+ ++
Sbjct: 223 RAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDEQVIR 282
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
RI S +++DYI G +PF+ ++PNA+ +A N++ ML P R + + L+ P++
Sbjct: 283 RIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLLEEPFV 342
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 242 bits (617), Expect = 1e-63
Identities = 128/346 (36%), Positives = 204/346 (57%), Gaps = 16/346 (4%)
Query: 18 DFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKL 77
D + ++F L K +G G+YGIV A + TVA+KK+ + F +R+ RE+
Sbjct: 6 DTHIHEKFDLQKRLGKGAYGIVWKAY--DKRSRETVALKKIFDAFRNPTDSQRTFREVMF 63
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIY 137
L+ F H N+ LY+ +F+ D +YL E ME D+H ++K G L D H Q +
Sbjct: 64 LQEFGKHPNVIKLYN---IFRADND-RDIYLAFEFMEADLHNVIKKGSILKDVHKQYIMC 119
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYS--ENPVENNQF--LTE 193
Q+ ++++HS +VLHRDLKP N+L++ADC++K+ DFGLAR S E+ E + LTE
Sbjct: 120 QLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTE 179
Query: 194 YVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGT 253
YVATRWYR+PEI+L+ + YTK +D+WS GCILAE+L G+ +F G ++Q+ RI+ +
Sbjct: 180 YVATRWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAK 239
Query: 254 PPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDD 313
P + IGS + ++ P+ P + + A+++++ +L F PQ R+TV+
Sbjct: 240 PSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQ 299
Query: 314 ALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTD 359
L HPY+ +H+P++EP+ ++E + Q+ ID+ D
Sbjct: 300 CLVHPYVVQFHNPSEEPV------LNYEVYPPLPDHIQLSIDDYRD 339
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 241 bits (616), Expect = 1e-63
Identities = 144/385 (37%), Positives = 224/385 (57%), Gaps = 32/385 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A +A + VAIKK++ F K
Sbjct: 49 YSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAY--DAVLDRNVAIKKLSRPFQNQTHAK 106
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL L++ HKNI L + VF P F +YL ELM+ ++ Q+++
Sbjct: 107 RAYRELVLMKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIQ--ME 160
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAG 215
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ +T YV TR+YRAPE++L GY + +D+WS GCI+ E++ K +F G+DY+DQ N+
Sbjct: 216 TSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNK 274
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA------------NPDAL 294
+++ LGTP E +K++ V++Y+ + F L+P++ A
Sbjct: 275 VIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQAR 333
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSF-ESVNEIEQLKQM 352
+LL ML DP RI+VDDALQHPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 334 DLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKEL 393
Query: 353 VIDEVTDFRQYVRLPLLHEQQQQQG 377
+ EV + + + ++ Q G
Sbjct: 394 IYKEVMNSEEKTKNGVVKGQPSPSG 418
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 241 bits (616), Expect = 1e-63
Identities = 144/385 (37%), Positives = 224/385 (57%), Gaps = 32/385 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A +A + VAIKK++ F K
Sbjct: 11 YSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAY--DAVLDRNVAIKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL L++ HKNI L + VF P F +YL ELM+ ++ Q+++
Sbjct: 69 RAYRELVLMKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIQ--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAG 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ +T YV TR+YRAPE++L GY + +D+WS GCI+ E++ K +F G+DY+DQ N+
Sbjct: 178 TSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA------------NPDAL 294
+++ LGTP E +K++ V++Y+ + F L+P++ A
Sbjct: 237 VIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSF-ESVNEIEQLKQM 352
+LL ML DP RI+VDDALQHPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 296 DLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQQQQQG 377
+ EV + + + ++ Q G
Sbjct: 356 IYKEVMNSEEKTKNGVVKGQPSPSG 380
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 240 bits (613), Expect = 3e-63
Identities = 142/365 (38%), Positives = 217/365 (58%), Gaps = 32/365 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ +V + FTV KR+Q +K IG G+ GIVC+A +A + VAIKK++ F K
Sbjct: 49 YSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAY--DAVLDRNVAIKKLSRPFQNQTHAK 106
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL L++ HKNI L + VF P F +YL ELM+ ++ Q+++
Sbjct: 107 RAYRELVLMKCVN-HKNIISLLN---VFTPQKTLEEFQDVYLVMELMDANLCQVIQ--ME 160
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 161 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAG 215
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ +T YV TR+YRAPE++L GY + +D+WS GCI+ E++ K +F G+DY+DQ N+
Sbjct: 216 TSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNK 274
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA------------NPDAL 294
+++ LGTP E +K++ V++Y+ + F L+P++ A
Sbjct: 275 VIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQAR 333
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSF-ESVNEIEQLKQM 352
+LL ML DP RI+VDDALQHPY+++W+DPA+ E + +D E + IE+ K++
Sbjct: 334 DLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKEL 393
Query: 353 VIDEV 357
+ EV
Sbjct: 394 IYKEV 398
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 238 bits (608), Expect = 1e-62
Identities = 137/302 (45%), Positives = 192/302 (63%), Gaps = 24/302 (7%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+ IG+G++G+V S T+ VA+KK+ NVF CKR RE+K+L FR H N+
Sbjct: 47 RPIGYGAFGVVWSV--TDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFR-HDNVL 103
Query: 89 CLYDMDIVFQP--DGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYI 146
L D + QP F LY+ ELM+ D+H+I+ S Q LT H + F+YQIL GLKY+
Sbjct: 104 SLLD---ILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYL 160
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H+A++LHRD+KPGNLLVN++C LKICDFGLAR + + N +T V T++YRAPE++
Sbjct: 161 HTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLN---MTHEVVTQYYRAPELL 217
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI--GS 264
+ + YT A+D+WS GCI AELL K +F+ ++QL I+ +LGTP +E +K G+
Sbjct: 218 MGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGA 277
Query: 265 KNVQDYIHQLGYIPKIP-FSTLYPNANPD-----ALNLLEGMLSFDPQLRITVDDALQHP 318
KN H L + P LY A+PD A++LL+ +L FDP RI+V++ALQH
Sbjct: 278 KN-----HVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHR 332
Query: 319 YL 320
YL
Sbjct: 333 YL 334
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 238 bits (608), Expect = 1e-62
Identities = 137/302 (45%), Positives = 192/302 (63%), Gaps = 24/302 (7%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+ IG+G++G+V S T+ VA+KK+ NVF CKR RE+K+L FR H N+
Sbjct: 72 RPIGYGAFGVVWSV--TDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFR-HDNVL 128
Query: 89 CLYDMDIVFQP--DGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYI 146
L D + QP F LY+ ELM+ D+H+I+ S Q LT H + F+YQIL GLKY+
Sbjct: 129 SLLD---ILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYL 185
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H+A++LHRD+KPGNLLVN++C LKICDFGLAR + + N +T V T++YRAPE++
Sbjct: 186 HTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLN---MTHEVVTQYYRAPELL 242
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI--GS 264
+ + YT A+D+WS GCI AELL K +F+ ++QL I+ +LGTP +E +K G+
Sbjct: 243 MGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGA 302
Query: 265 KNVQDYIHQLGYIPKIP-FSTLYPNANPD-----ALNLLEGMLSFDPQLRITVDDALQHP 318
KN H L + P LY A+PD A++LL+ +L FDP RI+V++ALQH
Sbjct: 303 KN-----HVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHR 357
Query: 319 YL 320
YL
Sbjct: 358 YL 359
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 238 bits (608), Expect = 1e-62
Identities = 137/302 (45%), Positives = 192/302 (63%), Gaps = 24/302 (7%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+ IG+G++G+V S T+ VA+KK+ NVF CKR RE+K+L FR H N+
Sbjct: 244 RPIGYGAFGVVWSV--TDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFR-HDNVL 300
Query: 89 CLYDMDIVFQP--DGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYI 146
L D + QP F LY+ ELM+ D+H+I+ S Q LT H + F+YQIL GLKY+
Sbjct: 301 SLLD---ILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYL 357
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H+A++LHRD+KPGNLLVN++C LKICDFGLAR + + N +T V T++YRAPE++
Sbjct: 358 HTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLN---MTHEVVTQYYRAPELL 414
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI--GS 264
+ + YT A+D+WS GCI AELL K +F+ ++QL I+ +LGTP +E +K G+
Sbjct: 415 MGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGA 474
Query: 265 KNVQDYIHQLGYIPKIP-FSTLYPNANPD-----ALNLLEGMLSFDPQLRITVDDALQHP 318
KN H L + P LY A+PD A++LL+ +L FDP RI+V++ALQH
Sbjct: 475 KN-----HVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHR 529
Query: 319 YL 320
YL
Sbjct: 530 YL 531
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 238 bits (606), Expect = 2e-62
Identities = 139/369 (37%), Positives = 217/369 (58%), Gaps = 27/369 (7%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
+T +V + +FT+ R+ ++ IG G+ GIVC+A T + VAIKK++ F K
Sbjct: 9 YTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDT--ITQQNVAIKKLSRPFQNVTHAK 66
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTD 129
R+ RE KL++ HKNI L + + F +YL ELM+ ++ Q+++ L
Sbjct: 67 RAYREFKLMK-LVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ--MDLDH 123
Query: 130 AHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ 189
+YQ+LCG+K++HSA ++HRDLKP N++V ADC LKI DFGLAR
Sbjct: 124 DRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLAR-----TAGTTF 178
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
+T YV TR+YRAPE++L GYT+ +D+WS GCI+ E++ G +F G D++DQ N+I++
Sbjct: 179 MMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIE 237
Query: 250 VLGTPPEETLKRIGSKNVQDYIHQ----LGY-IPKIPFSTLYPNAN--------PDALNL 296
LGTP ++R+ V++Y+ GY ++ L+PN N DA NL
Sbjct: 238 QLGTPSPSFMQRL-QPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNL 296
Query: 297 LEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFDFSF-ESVNEIEQLKQMVI 354
L ML DP+ RI+VD+AL+H Y+++W+D + + E +D S E + +EQ K+++
Sbjct: 297 LSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIY 356
Query: 355 DEVTDFRQY 363
+EV D+ +
Sbjct: 357 EEVMDYEAH 365
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 234 bits (597), Expect = 2e-61
Identities = 140/385 (36%), Positives = 217/385 (56%), Gaps = 32/385 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ ++ + FTV KR+Q +K IG G+ GIVC+A +A E VAIKK++ F K
Sbjct: 11 YSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAY--DAILERNVAIKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL L++ HKNI L + VF P F +Y+ ELM+ ++ Q+++
Sbjct: 69 RAYRELVLMKCVN-HKNIIGLLN---VFTPQKSLEEFQDVYIVMELMDANLCQVIQ--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAG 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ +T YV TR+YRAPE++L GY + +D+WS GCI+ E++ K +F G+DY+DQ N+
Sbjct: 178 TSFMMTPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA------------NPDAL 294
+++ LGTP E +K++ V+ Y+ F L+P+ A
Sbjct: 237 VIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPADEPICTEKFDFS--FESVNEIEQLKQM 352
+LL ML D RI+VD+ALQHPY+++W+DP++ K E + IE+ K++
Sbjct: 296 DLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQQQQQG 377
+ EV D + + ++ Q G
Sbjct: 356 IYKEVMDLEERTKNGVIRGQPSPLG 380
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 234 bits (597), Expect = 2e-61
Identities = 155/395 (39%), Positives = 228/395 (57%), Gaps = 44/395 (11%)
Query: 15 FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
+ Q V + Q + IG+G++G+V + T+ D VA+KK+ NVF + KR RE
Sbjct: 30 YYQPPAVPQDVQPDRPIGYGAFGVVWAV--TDPRDGRRVALKKLPNVFQSLVSSKRVFRE 87
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGM--FNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
LK+L F+ H+N+ D + QP + F +Y+ EL++ D+H+I+ S Q L+ H
Sbjct: 88 LKMLCFFK-HENVLSALD---ILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHI 143
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
+ F+YQIL GLKY+HSA +LHRD+KPGNLLVN++C LKICDFGLAR E P + + +T
Sbjct: 144 KVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLAR--VEEP-DQAKHMT 200
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
+ V T++YRAPEI++ + Y+ A+DVWS GCI ELLG + +F+ ++ V QL I ++LG
Sbjct: 201 QEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLG 260
Query: 253 TPPEETLKRI--GSKNVQDYIHQLGYIPKIP-FSTLY---PNANPDALNLLEGMLSFDPQ 306
TP E ++ G++ H L PK P FS LY +A +A++LL ML FDP
Sbjct: 261 TPTMEDMRHACEGART-----HMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPD 315
Query: 307 LRITVDDALQHPYLS----IWHD----------------PAD-EPICTEKFDFSFE-SVN 344
RI+V DAL HPYL +H AD EP + FD +E +
Sbjct: 316 KRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQPFDDLWERKLT 375
Query: 345 EIEQLKQMVIDEVTDFRQYVRLPLLHEQQQQQGKT 379
++Q+K+ + + + Q R+PL Q K+
Sbjct: 376 SVQQVKEEMHKFIAEQLQTGRVPLCINPQSAAFKS 410
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 233 bits (595), Expect = 4e-61
Identities = 139/380 (36%), Positives = 216/380 (56%), Gaps = 32/380 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ ++ + FTV KR+Q +K IG G+ GIVC+A +A E VAIKK++ F K
Sbjct: 11 YSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAY--DAILERNVAIKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL L++ HKNI L + VF P F +Y+ ELM+ ++ Q+++
Sbjct: 69 RAYRELVLMKCVN-HKNIIGLLN---VFTPQKSLEEFQDVYIVMELMDANLCQVIQ--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAG 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ +T YV TR+YRAPE++L GY + +D+WS GCI+ E++ K +F G+DY+DQ N+
Sbjct: 178 TSFMMTPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA------------NPDAL 294
+++ LGTP E +K++ V+ Y+ F L+P+ A
Sbjct: 237 VIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPADEPICTEKFDFS--FESVNEIEQLKQM 352
+LL ML D RI+VD+ALQHPY+++W+DP++ K E + IE+ K++
Sbjct: 296 DLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQ 372
+ EV D + + ++ Q
Sbjct: 356 IYKEVMDLEERTKNGVIRGQ 375
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 233 bits (595), Expect = 4e-61
Identities = 139/385 (36%), Positives = 216/385 (56%), Gaps = 32/385 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ ++ + FTV KR+Q +K IG G+ GIVC+A +A E VAIKK++ F K
Sbjct: 11 YSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAY--DAILERNVAIKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL L++ HKNI L + VF P F +Y+ ELM+ ++ Q+++
Sbjct: 69 RAYRELVLMKCVN-HKNIIGLLN---VFTPQKSLEEFQDVYIVMELMDANLCQVIQ--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAG 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ +T YV TR+YRAPE++L GY + +D+WS GCI+ E++ G +F G D++DQ N+
Sbjct: 178 TSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA------------NPDAL 294
+++ LGTP E +K++ V+ Y+ F L+P+ A
Sbjct: 237 VIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPADEPICTEKFDFS--FESVNEIEQLKQM 352
+LL ML D RI+VD+ALQHPY+++W+DP++ K E + IE+ K++
Sbjct: 296 DLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQQQQQG 377
+ EV D + + ++ Q G
Sbjct: 356 IYKEVMDLEERTKNGVIRGQPSPLG 380
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 233 bits (593), Expect = 6e-61
Identities = 138/380 (36%), Positives = 215/380 (56%), Gaps = 32/380 (8%)
Query: 10 HTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
++ ++ + FTV KR+Q +K IG G+ GIVC+A +A E VAIKK++ F K
Sbjct: 11 YSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAY--DAILERNVAIKKLSRPFQNQTHAK 68
Query: 70 RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGM---FNGLYLYEELMECDMHQIVKSGQP 126
R+ REL L++ HKNI L + VF P F +Y+ ELM+ ++ Q+++
Sbjct: 69 RAYRELVLMKCVN-HKNIIGLLN---VFTPQKSLEEFQDVYIVMELMDANLCQVIQ--ME 122
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LKI DFGLAR
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-----TAG 177
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ +T YV TR+YRAPE++L GY + +D+WS GCI+ E++ G +F G D++DQ N+
Sbjct: 178 TSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNK 236
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA------------NPDAL 294
+++ LGTP E +K++ V+ Y+ F L+P+ A
Sbjct: 237 VIEQLGTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQAR 295
Query: 295 NLLEGMLSFDPQLRITVDDALQHPYLSIWHDPADEPICTEKFDFS--FESVNEIEQLKQM 352
+LL ML D RI+VD+ALQHPY+++W+DP++ K E + IE+ K++
Sbjct: 296 DLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKEL 355
Query: 353 VIDEVTDFRQYVRLPLLHEQ 372
+ EV D + + ++ Q
Sbjct: 356 IYKEVMDLEERTKNGVIRGQ 375
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 231 bits (590), Expect = 1e-60
Identities = 122/247 (49%), Positives = 166/247 (66%), Gaps = 11/247 (4%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V +R+Q + +G G+YG VC+A T+ VA+KK++ F + KR+ REL+LL+H
Sbjct: 20 VPERYQNLSPVGSGAYGSVCAAFDTKTG--LRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQIL 140
+ H+N+ L D+ + FN +YL LM D++ IVK Q LTD H Q IYQIL
Sbjct: 78 MK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQIL 135
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GLKYIHSAD++HRDLKP NL VN DC+LKI DFGLAR + +T YVATRWY
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWY 188
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEIML++ Y + +D+WS GCI+AELL G+ +F G D++DQL IL+++GTP E LK
Sbjct: 189 RAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLK 248
Query: 261 RIGSKNV 267
+I S+++
Sbjct: 249 KISSESL 255
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 228 bits (580), Expect = 2e-59
Identities = 133/354 (37%), Positives = 202/354 (56%), Gaps = 31/354 (8%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
KR+Q ++ IG G+ GIVCSA T ++ VAIKK++ F KR+ RELKL+
Sbjct: 117 KRYQNLRLIGSGAQGIVCSAFDTVRNEQ--VAIKKLSRPFQNVTHAKRAYRELKLMS-LV 173
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
HKNI + + + FN LY+ ELM+ ++ Q+++ L +YQ+LCG
Sbjct: 174 NHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQ--MDLDHERLSYLLYQMLCG 231
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
++++HSA ++HRDLKP N++V +DC LKI DFGLAR E +T YV TR+YRA
Sbjct: 232 IRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIE-----AFMMTPYVVTRYYRA 286
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE++L GY + +DVWS GCI EL+ G+ +F G D++DQ RI++ LGTP L+R+
Sbjct: 287 PEVILG-MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERL 345
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPN------------ANPDALNLLEGMLSFDPQLRIT 310
V++Y+ PF L+ + A +LL ML DP+ RI+
Sbjct: 346 -QPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRIS 404
Query: 311 VDDALQHPYLSIWHDP----ADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDF 360
VDDAL+HPY+++W D A P+ +D + + ++ ++ + E+TD+
Sbjct: 405 VDDALRHPYVNVWFDEIEVYAPPPL---PYDHNMDVEQNVDSWREHIFRELTDY 455
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 221 bits (563), Expect = 2e-57
Identities = 126/334 (37%), Positives = 193/334 (57%), Gaps = 27/334 (8%)
Query: 1 MNEYDAVDRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTN 60
M Y ++ D TV+ F + K +G G+YGIV A T+ + TVA+KKV +
Sbjct: 1 MANYQTAHAQERRIQELDQTVESIFDVRKRMGKGAYGIVWKA--TDRRTKNTVALKKVFD 58
Query: 61 VFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQI 120
F +R+ RE+ LR FR H NI L D +F+ + YL E ME D+H +
Sbjct: 59 AFRDETDAQRTYREVIFLRAFRCHPNIVRLVD---IFKASNNLD-FYLVFEFMESDLHNV 114
Query: 121 VKSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGY 180
+K G L D H + +YQ++ +K+IHS +V+HRDLKP N+L+++ C+LK+ DFGLAR
Sbjct: 115 IKRGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTL 174
Query: 181 SE----NPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFK 236
S + +E + LT+YVATRWYRAPEI+++ + YTK ID+W GCIL E++ KP+F+
Sbjct: 175 SSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQ 234
Query: 237 GKDYVDQLNRILQVLGTPPEETLKRIG--------SKNVQ-DYIHQLGYIPKIPFSTLYP 287
G V+Q+ +I+ L + + IG S+N+Q D + L + K
Sbjct: 235 GTSTVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMK-------- 286
Query: 288 NANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
N D ++L++ +L +P R+T +A++HPY+S
Sbjct: 287 NCCDDGISLVKALLVLNPHNRLTAKEAIRHPYVS 320
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 213 bits (541), Expect = 7e-55
Identities = 130/335 (38%), Positives = 192/335 (56%), Gaps = 23/335 (6%)
Query: 19 FTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLL 78
F + R+ +K +G G G+V SA + + VAIKK+ V + K +LRE+K++
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDC--DKRVAIKKI--VLTDPQSVKHALREIKII 69
Query: 79 RHFRGHKNITCLYDMDIVFQPDGM-----------FNGLYLYEELMECDMHQIVKSGQPL 127
R H NI +++ + P G N +Y+ +E ME D+ +++ G PL
Sbjct: 70 RRL-DHDNIVKVFE---ILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PL 124
Query: 128 TDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNA-DCQLKICDFGLARGYSENPVE 186
+ H + F+YQ+L GLKYIHSA+VLHRDLKP NL +N D LKI DFGLAR +
Sbjct: 125 LEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-IMDPHYS 183
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ L+E + T+WYR+P ++LS YTKAID+W+ GCI AE+L GK +F G ++Q+
Sbjct: 184 HKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQL 243
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQ 306
IL+ + EE + + S + YI P P + L P + +AL+ LE +L+F P
Sbjct: 244 ILESIPVVHEEDRQELLSV-IPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFSPM 302
Query: 307 LRITVDDALQHPYLSIWHDPADEPICTEKFDFSFE 341
R+T ++AL HPY+SI+ P DEPI + F E
Sbjct: 303 DRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDE 337
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 209 bits (532), Expect = 8e-54
Identities = 133/356 (37%), Positives = 192/356 (53%), Gaps = 22/356 (6%)
Query: 28 IKEIGHGSYG-IVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKN 86
I+ +G GS+G ++ ++ VAIKK+ F +R RE KLL+ R H N
Sbjct: 121 IEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMR-HDN 179
Query: 87 ITCLYDMDIVFQPD--GMFNGLYLYEELMECDMHQIVKSGQP-----LTDAHYQSFIYQI 139
I C D ++ PD F +Y+ E ++QI+K + LTD H + IYQI
Sbjct: 180 IICALD---IYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQI 236
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRW 199
+ LKYIHSA+++HRDLKPGNL + D L I DFGLAR + LT+YV TRW
Sbjct: 237 IRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTS----LTQYVQTRW 292
Query: 200 YRAPEIML-SYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
YR+PE++ YT D+WS GCI AELL G+P+F G + Q RI Q+ G+P EE
Sbjct: 293 YRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEEL 352
Query: 259 LKRIGSKN---VQDYIHQLGYIPKIPFSTLYPNANP--DALNLLEGMLSFDPQLRITVDD 313
L +I + N ++ I + F ++ NP D ++LLE +L DP+ RITV++
Sbjct: 353 LTKIENDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEE 412
Query: 314 ALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPLL 369
A+QHPYL+ + P DEP FD + + V E+ ++++ PL+
Sbjct: 413 AIQHPYLAEFSLPEDEPRADHIFDLDDSQARTRFEWRDAVWKEIMNYKRLSSSPLI 468
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 199 bits (507), Expect = 6e-51
Identities = 128/386 (33%), Positives = 207/386 (53%), Gaps = 38/386 (9%)
Query: 2 NEYDAVDRHTFKV------FNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAI 55
NEYDA H + + FT+ R+ + + G+ G V A + VAI
Sbjct: 9 NEYDASRFHQVTIRDPIAGADSTFTIPTRYVNLSFLNAGAQGTVVMA--DDLVTTQRVAI 66
Query: 56 KKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPD---GMFNGLYLYEEL 112
KK+ F T+ KR+ RE LL + H NI L + F PD F +YL EL
Sbjct: 67 KKMQQPFVMTMSAKRAYREFILLTTIK-HPNIIRLLN---AFTPDTSLSTFREVYLVMEL 122
Query: 113 MECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKIC 172
M ++H+++ + L F+YQ LC +K++H++ V+HRDLKP N++VN C LK+
Sbjct: 123 MTHNLHEVIHRLR-LDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVL 181
Query: 173 DFGLARGYSENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGK 232
DFGLAR + V+ + +++YV TR+YRAPE++L Y++ +D+WS GCI AE++
Sbjct: 182 DFGLAR---KKNVDTSMRMSDYVVTRYYRAPEVILGLP-YSEKVDIWSVGCIFAEMINHT 237
Query: 233 PIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNAN-- 290
+F GKD +DQ +I VLGTP + + ++G ++ Y+ L FS + P+ N
Sbjct: 238 VLFPGKDRIDQWTKIYSVLGTPDDHFISQLG-QSAAMYVRSLPRHQARAFSEIVPDTNFL 296
Query: 291 PD------------ALNLLEGMLSFDPQLRITVDDALQHPYLSIW--HDPADEPICTEKF 336
P+ A +LL ML +P+ R +V+DAL HPY+ +W D + P ++
Sbjct: 297 PETENPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPYVKLWFKDDEVNAPASENRY 356
Query: 337 DFSFESVNE-IEQLKQMVIDEVTDFR 361
D + ++ + + K+++ +EV ++
Sbjct: 357 DQEIDFADKTLIEWKELIFNEVQRYQ 382
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 199 bits (506), Expect = 8e-51
Identities = 127/342 (37%), Positives = 198/342 (57%), Gaps = 25/342 (7%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
RF + +G G G+V SA + A + VA+KK+ ++++ K +LRE+K++R
Sbjct: 19 RFVDFQPLGFGVNGLVLSAVDSRACRK--VAVKKIALSDARSM--KHALREIKIIRRL-D 73
Query: 84 HKNITCLYDMDIVFQPDGM--------FNGLYLYEELMECDMHQIVKSGQPLTDAHYQSF 135
H NI +Y+ V P G F+ Y+ +E ME D+ ++++ G L + H + F
Sbjct: 74 HDNIVKVYE---VLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT-LAEEHAKLF 129
Query: 136 IYQILCGLKYIHSADVLHRDLKPGNLLVNA-DCQLKICDFGLARGYSENPVENNQFLTEY 194
+YQ+L GLKYIHSA+VLHRDLKP N+ ++ D LKI DFGLAR ++ + +L+E
Sbjct: 130 MYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQH-YSHKGYLSEG 188
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
+ T+WYR+P ++LS YTKAID+W+ GCILAE+L G+ +F G ++Q+ IL+ +
Sbjct: 189 LVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVI 248
Query: 255 PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDA 314
EE + V + K P L P N +A++ LE +L+F+P R+T +
Sbjct: 249 REEDKDEL--LRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMG 306
Query: 315 LQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDE 356
LQHPY+S + P DEP T + F E +EI+ + M ++
Sbjct: 307 LQHPYMSPYSCPEDEP--TSQHPFRIE--DEIDDIVLMAANQ 344
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 194 bits (494), Expect = 2e-49
Identities = 109/276 (39%), Positives = 158/276 (56%), Gaps = 24/276 (8%)
Query: 18 DFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKL 77
D + +R+ L +++G G+YGIV A + VAIKK+ + F +R+ RE+ L
Sbjct: 6 DPRIVRRYLLRRQLGQGAYGIVWKA--VDRRTGEVVAIKKIFDAFRDKTDAQRTFREITL 63
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMEC-----------------DMHQI 120
L+ F H NI L D+ I + D +YL E M C D++ +
Sbjct: 64 LQEFGDHPNIISLLDV-IRAEND---RDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAV 119
Query: 121 VKSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGY 180
++ G L D H +S YQ+L +++HS V+HRD KP N+L++A+C +K+CDFGLAR
Sbjct: 120 IRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSL 179
Query: 181 SENPV-ENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKD 239
+ P +Q +TEYVATRWYRAPE++LS YT +D+WS GCIL E+L G+P+F G
Sbjct: 180 GDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTS 239
Query: 240 YVDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLG 275
+ QL IL+ + P EE L +GS +HQLG
Sbjct: 240 TLHQLELILETIPPPSEEDLLALGSGCRASVLHQLG 275
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 191 bits (485), Expect = 2e-48
Identities = 102/261 (39%), Positives = 160/261 (61%), Gaps = 23/261 (8%)
Query: 111 ELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLK 170
ELM+ ++ Q+++ L +YQ+LCG+K++HSA ++HRDLKP N++V +DC LK
Sbjct: 2 ELMDANLCQVIQ--MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLK 59
Query: 171 ICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLG 230
I DFGLAR + +T YV TR+YRAPE++L GY + +D+WS GCI+ E++
Sbjct: 60 ILDFGLAR-----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVR 113
Query: 231 GKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNA- 289
K +F G+DY+DQ N++++ LGTP E +K++ V++Y+ + F L+P++
Sbjct: 114 HKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QPTVRNYVENRPKYAGLTFPKLFPDSL 172
Query: 290 -----------NPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD-EPICTEKFD 337
A +LL ML DP RI+VDDALQHPY+++W+DPA+ E + +D
Sbjct: 173 FPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYD 232
Query: 338 FSF-ESVNEIEQLKQMVIDEV 357
E + IE+ K+++ EV
Sbjct: 233 KQLDEREHTIEEWKELIYKEV 253
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 187 bits (476), Expect = 2e-47
Identities = 107/254 (42%), Positives = 156/254 (61%), Gaps = 17/254 (6%)
Query: 71 SLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL-TD 129
+LRE+K LR H NI L +++ + D LY E MEC+++Q++K Q L +
Sbjct: 13 NLREVKSLRRMN-HPNIVKL--KEVIRENDI----LYFVFEYMECNLYQLMKDRQKLFAE 65
Query: 130 AHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ 189
A +++ +Q+ GL Y+H HRDLKP NLLV+ D +KI DFGLAR + +P
Sbjct: 66 ADIKNWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKDI-IKIADFGLAREVNSSPP---- 120
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
TEYV+TRWYRAPE++L YT +D+W+ G I+AELL +PIF G D++ +I
Sbjct: 121 -FTEYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICS 179
Query: 250 VLGTPPEET-LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLR 308
V+GTP EET L+ + N +Y Q +P +P S+L P+A+ DA+NL+E + S+DP R
Sbjct: 180 VIGTPTEETWLEGLNLANTINY--QFPQLPGVPLSSLMPSASEDAINLIERLCSWDPSSR 237
Query: 309 ITVDDALQHPYLSI 322
T + LQHP+ +
Sbjct: 238 PTAAEVLQHPFFQV 251
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 181 bits (458), Expect = 3e-45
Identities = 113/299 (37%), Positives = 164/299 (54%), Gaps = 17/299 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
FQ +++IG G+YG+V A+ E VA+KK+ + ++RE+ LL+ + H
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQ--LVALKKIRLDLEMEGVPSTAIREISLLKELK-H 60
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS--GQPLTDAHYQSFIYQILCG 142
NI L +D+V LYL E + D+ + + S G L +S+++Q+L G
Sbjct: 61 PNIVRL--LDVVHNE----RKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQG 114
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
+ + HS V+HRDLKP NLL+N +K+ DFGLAR + P+ T V T WYRA
Sbjct: 115 VSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGV-PLRT---YTHEVVTLWYRA 170
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PEI+L + YT A+D+WS GCI AE++ K +F G +DQL RI ++LGTP E+T
Sbjct: 171 PEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWP-- 228
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
G + DY + + PN P+ +LL +L +DP RIT AL HPY S
Sbjct: 229 GVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 180 bits (456), Expect = 5e-45
Identities = 114/305 (37%), Positives = 176/305 (57%), Gaps = 24/305 (7%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETT------VAIKKVTNVFSKTLLCKRSLRELK 76
+R+ L+KE+G G++G V A + + T VAIK++ + C +LRE+K
Sbjct: 2 ERYTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMKKKYFSWEECV-NLREVK 60
Query: 77 LLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSG-QPLTDAHYQSF 135
L H NI L +++ + D LY E MEC+++Q++K + ++ +++
Sbjct: 61 SLSRMN-HPNIVKL--KEVIRENDI----LYFVFEYMECNLYQLMKDRPKHFAESDIRNW 113
Query: 136 IYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYV 195
+Q+ GL Y+H HRDLKP NLLV+ D +KI D GLAR +P TEYV
Sbjct: 114 CFQVFQGLSYMHQRGYFHRDLKPENLLVSKDV-IKIADLGLAREIDSSPP-----YTEYV 167
Query: 196 ATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPP 255
+TRWYRAPE++L YT +D+W+ G I+AELL +P+F G D++ +I V+G+P
Sbjct: 168 STRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPT 227
Query: 256 EET-LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDA 314
EET L+ + +V +Y Q P + S++ P A+ DA+NL+E + S+DP R T +A
Sbjct: 228 EETWLEGLNLASVINY--QFPQFPGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEA 285
Query: 315 LQHPY 319
LQHP+
Sbjct: 286 LQHPF 290
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 179 bits (453), Expect = 1e-44
Identities = 109/308 (35%), Positives = 168/308 (54%), Gaps = 18/308 (5%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ +Q +++IG G+YG+V AR + VA+KK+ + ++RE+ LL+
Sbjct: 2 ENYQKVEKIGEGTYGVVYKARHKLSG--RIVAMKKIRLEDESEGVPSTAIREISLLKEVN 59
Query: 83 GHKNIT-CLYDMDIVFQPDGMFNGLYLYEELMECD----MHQIVKSGQPLTDAHY-QSFI 136
N + C+ +DI+ + LYL E ++ D M +I ++G D Q F
Sbjct: 60 DENNRSNCVRLLDILHAE----SKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFT 115
Query: 137 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVA 196
YQ++ G+ + HS ++HRDLKP NLL++ + LK+ DFGLAR + P+ N T +
Sbjct: 116 YQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGV-PLRN---YTHEIV 171
Query: 197 TRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPE 256
T WYRAPE++L + Y+ +D+WS GCI AE++ P+F G +D++ +I QVLGTP E
Sbjct: 172 TLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNE 231
Query: 257 ETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQ 316
E G +QDY ++ + PN DA+ LL ML +DP RI+ ALQ
Sbjct: 232 EVWP--GVTLLQDYKSTFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQ 289
Query: 317 HPYLSIWH 324
YL +H
Sbjct: 290 QNYLRDFH 297
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 179 bits (453), Expect = 1e-44
Identities = 113/299 (37%), Positives = 167/299 (55%), Gaps = 18/299 (6%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
+++ +++IG G+YG+V AR + T+A+KK+ + ++RE+ LL+ +
Sbjct: 3 QYEKVEKIGEGTYGVVYKAR--DKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQ- 59
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLT-DAHY-QSFIYQILC 141
H NI YD D+V LYL E ++ D+ + + S + D H ++++YQIL
Sbjct: 60 HSNIV-KYD-DVVHSE----KRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILR 113
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWY 200
G+ Y HS VLHRDLKP NLL++ LK+ DFGLAR + PV T V T WY
Sbjct: 114 GIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGI-PVRT---FTHEVVTLWY 169
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPEI+L Y+ +D+WS GCI AE++ KP+F G +DQL +I +++GTP E+T +
Sbjct: 170 RAPEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWR 229
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
G ++ DY T PN +PD ++LL ML DP RI AL+H Y
Sbjct: 230 --GVTSLPDYKSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEY 286
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 178 bits (452), Expect = 1e-44
Identities = 104/322 (32%), Positives = 175/322 (54%), Gaps = 24/322 (7%)
Query: 18 DFTVDKR---FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRE 74
DF +++ ++ + IG G++GIVC A E + VAIKKV + + L +R+LRE
Sbjct: 72 DFKLERAAETYEPTQNIGSGAFGIVCEA--VETSSNQKVAIKKVAHASATPTLARRTLRE 129
Query: 75 LKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY-Q 133
+++LR+ H NI L D+ P G+ ++L +LM+ ++H I+ + + HY
Sbjct: 130 IRVLRYIN-HPNIVPLRDIFRTKGPLGI--DVFLVMDLMQNNLHHIIYGNEDPLEEHYIN 186
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR-----GYSENPVENN 188
+F+ Q+L GL+Y+H+A + HRDLKP NLLVN D L+I DFG+A+ + E+
Sbjct: 187 AFLGQLLRGLEYLHAACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHC 246
Query: 189 QFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRIL 248
++T++VAT YRAPE++ ++ A+D+W+ GCI E++ I G+ Q+ +L
Sbjct: 247 YYMTQHVATLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLL 306
Query: 249 QVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTL----------YPNANPDALNLLE 298
+LG PP+E + + + I G + + N D ++ ++
Sbjct: 307 TMLGQPPQEVINEVRCDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVK 366
Query: 299 GMLSFDPQLRITVDDALQHPYL 320
+ +D Q RI + DAL HPY+
Sbjct: 367 QLFQYDAQKRINIQDALLHPYI 388
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 178 bits (451), Expect = 2e-44
Identities = 125/370 (33%), Positives = 193/370 (51%), Gaps = 32/370 (8%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V R+ + +G G+YG+V A T+ + TVAIKK+ K + +LRE+KLL+
Sbjct: 7 VADRYLKREVLGQGTYGVVFKA--TDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKE 64
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP-LTDAHYQSFIYQI 139
+ H +I L D F L++ E ME D+ +++ L+ +S++ I
Sbjct: 65 LK-HPHIIELID---AFPHK---ENLHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMI 117
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRW 199
L GL+Y H VLHRD+KP NLL+ + QLK+ DFGLAR + + T V RW
Sbjct: 118 LKGLEYCHGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSP----GRKFTHQVFARW 173
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YRAPE++ + Y A+DVW+ GCI AELL +P +G +DQL++I GTP +
Sbjct: 174 YRAPELLFGAKQYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQW 233
Query: 260 KRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ + DY+ + ++P +L P + DAL+LL M ++DP+ RI++ AL+H Y
Sbjct: 234 PDMIC--LPDYV-EYQFVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQQALKHRY 290
Query: 320 LSIWHDPADE---PICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPLLHEQQQQQ 376
+ P D P K D + S +++E +K V+ FR+ + +
Sbjct: 291 FTSAPSPTDPLKLPRPVSKQD-AKSSDSKLEAIK--VLSPAHKFRRVM---------PDR 338
Query: 377 GKTDGGFDDQ 386
GK+ GF DQ
Sbjct: 339 GKSGNGFKDQ 348
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 178 bits (451), Expect = 2e-44
Identities = 110/309 (35%), Positives = 167/309 (53%), Gaps = 17/309 (5%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V R+ + +G G+YG+V A T+ E TVAIKK+ + + +LRE+K+L+
Sbjct: 8 VADRYLKQEVLGQGTYGVVFKA--TDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKE 65
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP-LTDAHYQSFIYQI 139
+ H +I L D F L+L E ME D+ +++ L+ A +S++
Sbjct: 66 LK-HPHIILLID---AFPHK---ENLHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMT 118
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRW 199
GL Y H VLHRD+KP NLL+ D QLK+ DFGLAR + N+ T V RW
Sbjct: 119 FKGLAYCHDKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFGSP----NRKFTHQVFARW 174
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YRAPE++ + Y A+DVW+ CI AELL +P +G +DQL++I GTP +
Sbjct: 175 YRAPELLFGAKQYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQW 234
Query: 260 KRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ + DY+ + ++P +L+P + DAL+LL M ++DP+ RI++ AL+H Y
Sbjct: 235 PDL--TKLPDYV-EYQFVPAPSLRSLFPAVSDDALDLLSKMFTYDPKARISIKQALEHRY 291
Query: 320 LSIWHDPAD 328
+ P D
Sbjct: 292 FTSAPAPTD 300
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 176 bits (447), Expect = 6e-44
Identities = 113/300 (37%), Positives = 160/300 (52%), Gaps = 19/300 (6%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+G G+YG+V A T+ TVA+KK+ K + +LRE+KLL+ H +I L
Sbjct: 19 LGEGTYGVVYKA--TDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELN-HPHIVEL 75
Query: 91 YDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP-LTDAHYQSFIYQILCGLKYIHSA 149
D F DG L+L E M+ D+ +++ L+ +S++ L GL Y H
Sbjct: 76 ID---AFPHDG---SLHLVFEYMQTDLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKK 129
Query: 150 DVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIMLSY 209
VLHRD+KP NLL+ + LK+ DFGLAR + N+ T V WYRAPE++
Sbjct: 130 WVLHRDMKPNNLLIGENGLLKLADFGLARLFGSP----NRRFTHQVFATWYRAPELLFGS 185
Query: 210 QGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP-PEETLKRIGSKNVQ 268
+ Y +DVW+ GCI AELL +P G +DQL +I Q GTP P + I +
Sbjct: 186 RQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMI---YLP 242
Query: 269 DYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPAD 328
DY+ + Y P P T++P A+ DAL+LL M +DP+ RIT+ AL H Y S P +
Sbjct: 243 DYM-EFSYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDHRYFSSSPSPTE 301
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 173 bits (439), Expect = 5e-43
Identities = 112/301 (37%), Positives = 165/301 (54%), Gaps = 21/301 (6%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ +++IG G+YG+V AR + VA+KK+ + ++RE+ LL+
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTGE--VVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS----GQPLTDAHYQSFIYQ 138
H NI L +D++ N LYL E + D+ + + + G PL +S+++Q
Sbjct: 60 -HPNIVKL--LDVIHTE----NKLYLVFEFLHQDLKKFMDASALTGIPLP--LIKSYLFQ 110
Query: 139 ILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATR 198
+L GL + HS VLHRDLKP NLL+N + +K+ DFGLAR + PV T V T
Sbjct: 111 LLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRT---YTHEVVTL 166
Query: 199 WYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
WYRAPEI+L + Y+ A+D+WS GCI AE++ + +F G +DQL RI + LGTP E
Sbjct: 167 WYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVV 226
Query: 259 LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHP 318
G ++ DY + FS + P + D +LL ML +DP RI+ AL HP
Sbjct: 227 WP--GVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
Query: 319 Y 319
+
Sbjct: 285 F 285
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 173 bits (438), Expect = 6e-43
Identities = 110/302 (36%), Positives = 164/302 (53%), Gaps = 17/302 (5%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+ I+++G G+YG V R E+ + +AIKK+ F C +LRE+K L+
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGE--LIAIKKMKRKFYSWEECM-NLREVKSLKKLN- 58
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL-TDAHYQSFIYQILCG 142
H N+ L +++ + D LY E M+ +++Q++K L ++ ++ +YQIL G
Sbjct: 59 HANVVKL--KEVIRENDH----LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQG 112
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
L +IH HRDLKP NLL +KI DFGLAR P T+YV+TRWYRA
Sbjct: 113 LAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPP-----YTDYVSTRWYRA 167
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE++L Y+ IDVW+ GCI+AE+ +P+F G +D + +I QVLGTP +
Sbjct: 168 PEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEG 227
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
+ +P TL PNA+ +A+ LL ML +DP+ R T AL++PY +
Sbjct: 228 YQLSSAMNFRWPQCVPN-NLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQV 286
Query: 323 WH 324
H
Sbjct: 287 GH 288
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 173 bits (438), Expect = 6e-43
Identities = 116/301 (38%), Positives = 169/301 (55%), Gaps = 20/301 (6%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+++++E+G G+ G V A E + VA+KK+ F C +LRE+K LR
Sbjct: 11 RYKILEELGDGTCGSVYKAVNLETYE--VVAVKKMKRKFYYWEECV-NLREVKALRKLN- 66
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCG 142
H +I L +IV + N L+ E M+ +++ I+K + P ++ +SF+ Q+L G
Sbjct: 67 HPHIIKL--KEIVRE----HNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQG 120
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
L ++H HRDLKP NLLV + LKI DFGLAR + P TEYV+TRWYRA
Sbjct: 121 LAHMHKNGYFHRDLKPENLLVTNNI-LKIADFGLAREVASMPP-----YTEYVSTRWYRA 174
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE++L YT A+D+W+ G ILAEL P+F G+ +DQL +I VLG P T
Sbjct: 175 PEVLLQSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEA 234
Query: 263 GS-KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
S + H P+ + L PNA P+A++L+ + S+DP R T D+AL HP+ S
Sbjct: 235 KSISRIMSISHT--EFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFFS 292
Query: 322 I 322
+
Sbjct: 293 M 293
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 172 bits (436), Expect = 1e-42
Identities = 114/314 (36%), Positives = 168/314 (53%), Gaps = 22/314 (7%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVT---NVFSKTLLCKRSLRELKLLR 79
KR++ + +G G + V AR + VAIKK+ +K + + +LRE+KLL+
Sbjct: 10 KRYEKLDFLGEGQFATVYKAR--DKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 80 HFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQ 138
H NI L D G + + L + ME D+ I+K LT +H ++++
Sbjct: 68 EL-SHPNIIGLLDAF------GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM 120
Query: 139 ILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATR 198
L GL+Y+H +LHRDLKP NLL++ + LK+ DFGLA+ + N+ T V TR
Sbjct: 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSP----NRAYTHQVVTR 176
Query: 199 WYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
WYRAPE++ + Y +D+W+ GCILAELL P G +DQL RI + LGTP EE
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQ 236
Query: 259 LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHP 318
+ S + DY+ + P IP ++ A D L+L++G+ F+P RIT AL+
Sbjct: 237 WPDMCS--LPDYVTFKSF-PGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMK 293
Query: 319 YLSIWHDPADEPIC 332
Y S + P P C
Sbjct: 294 YFS--NRPGPTPGC 305
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 171 bits (434), Expect = 2e-42
Identities = 109/302 (36%), Positives = 162/302 (53%), Gaps = 17/302 (5%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+ I+++G G+YG V R E+ + +AIKK+ F C RE+K L+
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGE--LIAIKKMKRKFYSWEECMNQ-REVKSLKKLN- 58
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL-TDAHYQSFIYQILCG 142
H N+ L +++ + D LY E M+ +++Q++K L ++ ++ +YQIL G
Sbjct: 59 HANVVKL--KEVIRENDH----LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQG 112
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
L +IH HRDLKP NLL +KI DFGLAR P T+YV+TRWYRA
Sbjct: 113 LAFIHKLGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPP-----YTDYVSTRWYRA 167
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE++L Y+ IDVW+ GCI+AE+ +P+F G +D + +I QVLGTP +
Sbjct: 168 PEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEG 227
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
+ +P TL PNA+ +A+ LL ML +DP+ R T AL++PY +
Sbjct: 228 YQLSSAMNFRWPQCVPN-NLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQV 286
Query: 323 WH 324
H
Sbjct: 287 GH 288
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 171 bits (433), Expect = 2e-42
Identities = 123/365 (33%), Positives = 191/365 (51%), Gaps = 42/365 (11%)
Query: 19 FTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLL 78
FT+ R+ +K + G+ GIV A + VAIKK+ F T+ +R+ RE LL
Sbjct: 23 FTIPTRYVNLKFLNVGAQGIVVMA--DDLVTTQRVAIKKMQQPFLLTMSARRAYREFILL 80
Query: 79 RHFRGHKNITCLYDMDIVFQPD---GMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSF 135
+ H NI L + F PD F +YL E M ++H+++ + D SF
Sbjct: 81 TTLK-HPNIIRLLN---AFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLR--LDHETLSF 134
Query: 136 -IYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
+YQ LC +K++H+ +HRDLKP N++VN C LK+ DFGLAR + + +++Y
Sbjct: 135 LVYQSLCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARRRNV-----DMRMSDY 189
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
V TR+YRAPE++L Y++ +D+WS GCILAE++ +F GKD DQ +I VL TP
Sbjct: 190 VGTRYYRAPEVILGL-NYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTP 248
Query: 255 PE---ETLKRIGSKNVQDYIHQL--GYIPKIPFSTLYPNA-NPD-------ALNLLEGML 301
+ L+ IG+ V+ L + +P S P NP A +LL ML
Sbjct: 249 DDHFINQLEPIGAVYVRSLPQHLARAFNEIVPDSNFLPETENPKDHLTLHMARDLLFNML 308
Query: 302 SFDPQLRITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVNEIE-----QLKQMVIDE 356
+P+ R +V+DAL HPY D+ + + + VN+I+ + K+++ +E
Sbjct: 309 KINPEERYSVEDALNHPY------TMDDEVNAPASEIPDDEVNDIDDWTLIEWKRLIFNE 362
Query: 357 VTDFR 361
V ++
Sbjct: 363 VQGYQ 367
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 170 bits (430), Expect = 5e-42
Identities = 130/365 (35%), Positives = 183/365 (49%), Gaps = 32/365 (8%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ +++IG G+YG V A+ + + VA+KK+ + ++RE+K+L+ H
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGE--IVALKKIRMDNEREGFPITAIREIKILKKLH-H 82
Query: 85 KNITCLY--------DMDIVFQPDG--MFNGLYLYEELMECDMHQIV-KSGQPLTDAHYQ 133
+N+ L D D +PD G+Y+ E M+ D+ + + G T +
Sbjct: 83 ENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIK 142
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
++ Q+L GL Y H VLHRD+K NLL++ + LK+ DFGLAR YS + N LT
Sbjct: 143 CYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGN---LTN 199
Query: 194 YVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGT 253
V T WYR PE++L Y AID+WS GCI AELL GKPI GK +QLN+I ++ G+
Sbjct: 200 RVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGS 259
Query: 254 PPEETLKRIGSKNVQDYIHQLGYIP-KIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
P E G + Y P K +Y + + AL LLE ML DP RI
Sbjct: 260 PDESNWP--GVSKMPWYNQMKSSRPLKRRVREIYRHFDRHALELLEKMLVLDPSQRICAK 317
Query: 313 DALQHPYLSIWHDPADEPICTEKFDFSFESVNEIEQLK---QMVIDEVTDFRQYVRLPLL 369
DAL Y W DP C K ++ES +E + K QM +E +Q L
Sbjct: 318 DALDAEY--FWTDPLP---CDPKSLPTYESSHEFQTKKKRQQMRHNEEAAKKQ----KLQ 368
Query: 370 HEQQQ 374
H QQQ
Sbjct: 369 HPQQQ 373
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 169 bits (429), Expect = 7e-42
Identities = 113/306 (36%), Positives = 169/306 (54%), Gaps = 17/306 (5%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
++++ +++IG G+YG V A+ E + VA+K+V + +LRE+ LL+ +
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETHE--IVALKRVRLDDDDEGVPSSALREICLLKELK 59
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY-QSFIYQILC 141
HKNI L+D V D L L E + D+ + S D +SF++Q+L
Sbjct: 60 -HKNIVRLHD---VLHSD---KKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLK 112
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
GL + HS +VLHRDLKP NLL+N + +LK+ DFGLAR + PV + + V T WYR
Sbjct: 113 GLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFG-IPV---RCYSAEVVTLWYR 168
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELL-GGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
P+++ + Y+ +ID+WS GCI AEL G+P+F G D DQL RI ++LGTP EE
Sbjct: 169 PPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWP 228
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
+ + DY Y + P N +LL+ +L +P RI+ ++ALQHPY
Sbjct: 229 SM--TKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
Query: 321 SIWHDP 326
S + P
Sbjct: 287 SDFCPP 292
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 169 bits (429), Expect = 7e-42
Identities = 109/297 (36%), Positives = 161/297 (53%), Gaps = 18/297 (6%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
I++IG G+YG+V R VA+KK+ + + ++RE+ LL+ R H NI
Sbjct: 7 IEKIGEGTYGVVYKGRHKTTGQ--VVAMKKIRLESEEEGVPSTAIREISLLKELR-HPNI 63
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS---GQPLTDAHYQSFIYQILCGLK 144
L D V D LYL E + D+ + + S GQ + + +S++YQIL G+
Sbjct: 64 VSLQD---VLMQDSR---LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIV 117
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
+ HS VLHRDLKP NLL++ +K+ DFGLAR + P+ + T V T WYR+PE
Sbjct: 118 FCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGI-PI---RVYTHEVVTLWYRSPE 173
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++L Y+ +D+WS G I AEL KP+F G +DQL RI + LGTP E +
Sbjct: 174 VLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV-- 231
Query: 265 KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
+++QDY + ++ N + + L+LL ML +DP RI+ AL HPY +
Sbjct: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 169 bits (429), Expect = 7e-42
Identities = 110/302 (36%), Positives = 172/302 (56%), Gaps = 18/302 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ + +I G+YG+V A+ + + VA+KKV + SLRE+ +L F H
Sbjct: 406 FERLNKIDEGTYGVVYRAKDKKTGE--IVALKKVKMEKEREGFPLTSLREINILLSFH-H 462
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
+I + ++ + D +F + E ME D+ ++++ Q + + + + Q+L G+
Sbjct: 463 PSIVDVKEVVVGSSLDSIF----MVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGV 518
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
KY+H VLHRDLK NLL+N +LKICDFGLAR Y +P++ T V T WYRAP
Sbjct: 519 KYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLARQYG-SPLKP---YTHLVVTLWYRAP 574
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET---LK 260
E++L + Y+ AID+WS GCI+AELL P+F GK DQL++I ++LGTP E
Sbjct: 575 ELLLGAKQYSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFS 634
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLY---PNANPDALNLLEGMLSFDPQLRITVDDALQH 317
++ V HQ + K +T + P + +LL +L++DP+ RITV++AL+H
Sbjct: 635 KLPGVKVNFVKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKH 694
Query: 318 PY 319
+
Sbjct: 695 DW 696
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 169 bits (427), Expect = 1e-41
Identities = 108/300 (36%), Positives = 165/300 (55%), Gaps = 17/300 (5%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+ ++++G G+YG V + E+ + VAIK++ F C +LRE+K L+
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGE--LVAIKRMKRKFYSWDECM-NLREVKSLKKLN- 58
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL-TDAHYQSFIYQILCG 142
H N+ L +++ + D LY E M+ +++Q++K L ++ ++ +YQIL G
Sbjct: 59 HANVIKL--KEVIRENDH----LYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQG 112
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
L +IH HRD+KP NLL +KI DFGLAR P T+YV+TRWYRA
Sbjct: 113 LAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPP-----YTDYVSTRWYRA 167
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE++L Y+ IDVW+ G I+AEL +P+F G VD++ +I QVLGTP +
Sbjct: 168 PEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPE- 226
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
G + + I TL PNA+ +A+ L+ ML++DP+ R T AL+HPY +
Sbjct: 227 GYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQV 286
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 167 bits (424), Expect = 3e-41
Identities = 113/301 (37%), Positives = 169/301 (55%), Gaps = 17/301 (5%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+++ +++IG G+YG V R + + VA+K+V + +LRE+ LL+ +
Sbjct: 2 QKYDKMEKIGEGTYGTVFKGRNRDTME--IVALKRVRLDEDDEGVPSSALREICLLKELK 59
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTD-AHYQSFIYQILC 141
HKNI L D V D L L E + D+ + S D A +SF+ Q+L
Sbjct: 60 -HKNIVRLID---VLHSD---KKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLR 112
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
GL + HS +VLHRDLKP NLL+N + +LK+ DFGLAR + PV + + V T WYR
Sbjct: 113 GLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFG-IPV---KCYSAEVVTLWYR 168
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELL-GGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
P+++ + YT +ID+WS GCILAEL G+P+F G D +DQL +I +VLGTP E++
Sbjct: 169 PPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWP 228
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
G ++ DY+ + +S L P N +LL+ +L P RI+ + A+QHPY
Sbjct: 229 --GVSHLSDYVALPSFPAITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYF 286
Query: 321 S 321
+
Sbjct: 287 T 287
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 167 bits (424), Expect = 3e-41
Identities = 104/301 (34%), Positives = 164/301 (53%), Gaps = 16/301 (5%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVA-IKKVTNVFSKTLLCKRSLRELKLLRHF 81
+R+ + +G G + V AR T V IKK + ++ + + +LRE+K+L+
Sbjct: 10 ERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQEL 69
Query: 82 RGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP-LTDAHYQSFIYQIL 140
+ H+NI L D VF G + + L + M+ D+ I+K + LT A+ +++ L
Sbjct: 70 Q-HENIIGLVD---VF---GQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTL 122
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GL+Y+H +LHRDLKP NLLVN+D LKI DFGLA+ + N+ T +V TRWY
Sbjct: 123 KGLEYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSP----NRIYTHHVVTRWY 178
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
R+PE++ + Y +D+W+ GCILAEL+ P G +DQL RI LGTP E
Sbjct: 179 RSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWP 238
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
+ + DY+ Q P P ++ A D ++L++ + + +P R++ +AL PY
Sbjct: 239 HL--SKLHDYL-QFRNFPGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295
Query: 321 S 321
+
Sbjct: 296 A 296
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 167 bits (422), Expect = 4e-41
Identities = 112/320 (35%), Positives = 172/320 (53%), Gaps = 33/320 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+++ L+ +IG G+YG+V AR T+ + +AIKK + ++RE+ LLR
Sbjct: 23 QQYNLVGKIGEGTYGLVFLAR-TKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREI- 80
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV-----KSGQPLTDAHYQSFIY 137
H+N+ L ++ I F LYL + E D+++I+ K G L +S ++
Sbjct: 81 SHENVVKLVNVHINFAD----MSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLW 136
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQ----LKICDFGLARGYSE--NPVENNQFL 191
Q+L GL Y+HS ++HRDLKP N+LV D + +KI DFGLAR Y P+ +N
Sbjct: 137 QLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGV- 195
Query: 192 TEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKD--------YVDQ 243
V T WYRAPE++L + YT A+D+W+ GCI AELL KP+F+G + +DQ
Sbjct: 196 ---VVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQ 252
Query: 244 LNRILQVLGTPPEETLKRIGS----KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEG 299
L++I ++LG P + + + +N +I Y + ++ N A +LL
Sbjct: 253 LDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSK 312
Query: 300 MLSFDPQLRITVDDALQHPY 319
ML +DP RIT AL+H Y
Sbjct: 313 MLEYDPLKRITASQALEHEY 332
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 167 bits (422), Expect = 4e-41
Identities = 112/312 (35%), Positives = 172/312 (54%), Gaps = 37/312 (11%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETT---VAIKKVT---NVFSKTL-LCKRSLRELKL 77
FQ + +I G+YGIV AR DE T VA+KK+ + F + SLRE+ +
Sbjct: 297 FQKLNKINEGTYGIVYKAR-----DEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINI 351
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV-KSGQPLTDAHYQSFI 136
L H I + ++ + + D N +Y+ E +E D+ ++ + +P + + + +
Sbjct: 352 LLSCN-HPAIVNVKEVVVGGKND---NDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLM 407
Query: 137 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVA 196
Q+L GLKY+H+ ++HRDLKP NLL+N +LKICDFG+AR Y +P++ T+ V
Sbjct: 408 MQLLDGLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYG-SPIKP---YTQMVI 463
Query: 197 TRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPE 256
T+WYR PE++L + Y+ A+D+WS GCI+AELL KP+F GK +DQL +I VLGTP E
Sbjct: 464 TQWYRPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNE 523
Query: 257 ETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPN-----------ANPDALNLLEGMLSFDP 305
S + + P P++ L + +LL +L+ DP
Sbjct: 524 AIWPGFSS-----FPNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDP 578
Query: 306 QLRITVDDALQH 317
+ R+TV+DAL H
Sbjct: 579 EKRLTVEDALNH 590
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 166 bits (421), Expect = 6e-41
Identities = 112/305 (36%), Positives = 168/305 (54%), Gaps = 25/305 (8%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V +F+++ +G G+YG+V R E + VAIKK + + + +LRELK+LR
Sbjct: 9 VMNKFEILGVVGEGAYGVVLKCRHKETHE--IVAIKKFKDSEENEEVKETTLRELKMLRT 66
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK---SGQPLTDAHYQSFIY 137
+ +NI L + F+ G LYL E +E +M ++++ +G P +S+IY
Sbjct: 67 LK-QENIVELKE---AFRRRGK---LYLVFEYVEKNMLELLEEMPNGVP--PEKVKSYIY 117
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVAT 197
Q++ + + H D++HRD+KP NLL++ + LK+CDFG AR SE NN TEYVAT
Sbjct: 118 QLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEG---NNANYTEYVAT 174
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEE 257
RWYR+PE++L Y K++D+WS GCIL EL G+P+F G+ +DQL I +VLG P E
Sbjct: 175 RWYRSPELLLG-APYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSE 233
Query: 258 TLKRIGSKNVQDYIHQLGY----IPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDD 313
+K S H L + P+ N L+L++ +L DP R +
Sbjct: 234 QMKLFYS---NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQ 290
Query: 314 ALQHP 318
L HP
Sbjct: 291 CLNHP 295
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 166 bits (419), Expect = 1e-40
Identities = 101/299 (33%), Positives = 165/299 (54%), Gaps = 18/299 (6%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
K ++ I +IG G++ V + D A K++ F +++ +LRE++ LR
Sbjct: 2 KNYKAIGKIGEGTFSEVM--KMQSLRDGNYYACKQMKQRF-ESIEQVNNLREIQALRRLN 58
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILC 141
H NI L++ +VF D L L ELM+ +++++++ + PL++ ++YQ+
Sbjct: 59 PHPNILMLHE--VVF--DRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCK 114
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARG-YSENPVENNQFLTEYVATRWY 200
L +IH + HRD+KP N+L+ D LK+ DFG R YS+ P TEY++TRWY
Sbjct: 115 SLDHIHRNGIFHRDVKPENILIKQDV-LKLGDFGSCRSVYSKQPY------TEYISTRWY 167
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPE +L+ YT +D+WS GC+ E+ +P+F G + +DQ+++I V+GTP ++ L
Sbjct: 168 RAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILT 227
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ ++ IP T N +P L+LL M+++DP RI ALQHPY
Sbjct: 228 KFKQSRAMNFDFPFKKGSGIPLLT--TNLSPQCLSLLHAMVAYDPDERIAAHQALQHPY 284
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 165 bits (417), Expect = 2e-40
Identities = 104/305 (34%), Positives = 163/305 (53%), Gaps = 28/305 (9%)
Query: 25 FQLIKEIGHGSYGIVCSAR-FTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
++ ++++G G+YG+V A + VA+KK+ + ++RE+ LL+ +
Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKD 67
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS---GQPLTDAHYQSFIYQIL 140
NI LYD + D + LYL E ++ D+ + ++ QPL + F+ Q+
Sbjct: 68 D-NIVRLYD---IVHSDA--HKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLC 121
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
G+ Y HS +LHRDLKP NLL+N D LK+ DFGLAR + P+ + T + T WY
Sbjct: 122 KGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGV-PL---RAYTHEIVTLWY 177
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPE++L + Y+ +D WS GCI AE+ KPIF G +DQ+ +I +VLGTP E
Sbjct: 178 RAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIW- 236
Query: 261 RIGSKNVQDYIHQLGYIPKIP------FSTLYPNANPDALNLLEGMLSFDPQLRITVDDA 314
D ++ + P P S + P+ +P ++LL+ +L++DP RI+ A
Sbjct: 237 -------PDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRA 289
Query: 315 LQHPY 319
HPY
Sbjct: 290 AIHPY 294
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 164 bits (415), Expect = 3e-40
Identities = 119/364 (32%), Positives = 182/364 (49%), Gaps = 29/364 (7%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ +++IG G+YG V A+ + + VA+KK+ + ++RE+K+L+ H
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGE--IVALKKIRMDNEREGFPITAIREIKILKKLH-H 82
Query: 85 KNITCLY--------DMDIVFQPDG--MFNGLYLYEELMECDMHQIV-KSGQPLTDAHYQ 133
+N+ L D D +PD G+Y+ E M+ D+ + + G T +
Sbjct: 83 ENVIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIK 142
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
++ Q+L GL Y H VLHRD+K NLL++ + LK+ DFGLAR YS + N LT
Sbjct: 143 CYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGN---LTN 199
Query: 194 YVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGT 253
V T WYR PE++L Y AID+WS GCI AELL KPI GK+ +QLN+I ++ G+
Sbjct: 200 RVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGS 259
Query: 254 PPEETLKRIGSKNVQDYIHQLGYIPKIPFS----TLYPNANPDALNLLEGMLSFDPQLRI 309
P E+ + + + P P + + + AL LLE ML DP RI
Sbjct: 260 PDEKLWPGVSKMPWFN-----NFKPARPLKRRVREFFRHFDRHALELLEKMLVLDPAQRI 314
Query: 310 TVDDALQHPYLSIWHDPAD-EPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPL 368
+ DAL Y W DP +P ++ S E + ++ +Q +E ++ PL
Sbjct: 315 SAKDALDAEY--FWTDPLPCDPKSLPTYESSHEFQTKKKRQQQRQNEEAAKRQKLQHPPL 372
Query: 369 LHEQ 372
H +
Sbjct: 373 QHSR 376
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 163 bits (413), Expect = 5e-40
Identities = 105/302 (34%), Positives = 166/302 (54%), Gaps = 20/302 (6%)
Query: 20 TVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLR 79
T+ FQ ++IG G+YGIV AR + VA+KK+ + ++RE+ LL+
Sbjct: 3 TILDNFQRAEKIGEGTYGIVYKARSNSTGQD--VALKKIRLEGETEGVPSTAIREISLLK 60
Query: 80 HFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV-KSGQPLTDAHYQSFIYQ 138
+ + H N+ L+D+ I N LY+ E + D+ +++ K T +S+++Q
Sbjct: 61 NLK-HPNVVQLFDVVI------SGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQ 113
Query: 139 ILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATR 198
IL + + H+ +LHRDLKP NLLV+ ++K+ DFGLAR ++ P+ + T V T
Sbjct: 114 ILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNV-PM---RAYTHEVVTL 169
Query: 199 WYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
WYRAPEI+L + Y+ +D+WS GCI +E++ + +F G +DQL RI + L TP E
Sbjct: 170 WYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETN 229
Query: 259 LKRIGSKNVQDYIHQLGYIPKIPFSTL-YPNANPDALNLLEGMLSFDPQLRITVDDALQH 317
G + D+ + P+ + + P +A L+ ML +DP LRI+ DALQH
Sbjct: 230 WP--GVTQLPDFKTK---FPRWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQH 284
Query: 318 PY 319
Y
Sbjct: 285 AY 286
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 163 bits (413), Expect = 5e-40
Identities = 100/300 (33%), Positives = 161/300 (53%), Gaps = 18/300 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ I++IG G+YG+V R VA+KK+ + ++RE+ LL+ + H
Sbjct: 4 FEKIEKIGEGTYGVVYKGR--NRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELK-H 60
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS---GQPLTDAHYQSFIYQILC 141
+NI CL D V + N +YL E + D+ + + S + + +S++YQI
Sbjct: 61 ENIVCLED---VLMEE---NRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITS 114
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
+ + H VLHRDLKP NLL++ +K+ DFGL R + PV + T + T WYR
Sbjct: 115 AILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGI-PV---RIYTHEIVTLWYR 170
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L Y+ +D+WS GCI AE+ KP+F+G +DQL R+ ++L TP E+
Sbjct: 171 APEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWP- 229
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
G ++ DY + + N + + ++L++ ML +DP RI+ D L+HPY +
Sbjct: 230 -GVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFN 288
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 163 bits (412), Expect = 6e-40
Identities = 104/298 (34%), Positives = 163/298 (53%), Gaps = 19/298 (6%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+ + ++G G+YG V + + ++ VAIK++ + +LRE+K L+
Sbjct: 3 RYITLTQLGDGTYGTVVLGQRKDTGEK--VAIKRMKRKYYSWEEAM-NLREVKSLKKL-S 58
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP-LTDAHYQSFIYQILCG 142
H NI L +++ + D LY E M+ +++Q++K L + +S ++Q+L G
Sbjct: 59 HPNIVKL--KEVIRENDT----LYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTG 112
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
L ++H HRDLKP NLL + +KI DFGLAR P T+YV+TRWYRA
Sbjct: 113 LAFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRPP-----FTDYVSTRWYRA 167
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE++L Y ID+W+ GCI+AEL +P+F G VDQL +I VLGTP ++
Sbjct: 168 PEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWP-- 225
Query: 263 GSKNVQDYIH-QLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ IH + K+P S++ + + L+LLE ML++DP R T +L++PY
Sbjct: 226 DGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPY 283
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 162 bits (411), Expect = 8e-40
Identities = 108/313 (34%), Positives = 165/313 (52%), Gaps = 26/313 (8%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+++G G+Y +V R E VAIKK+ K + +LRE+K LR R H N+
Sbjct: 15 RKVGEGTYAVVFLGRQKET--NRRVAIKKIKVGQFKDGIDISALREIKFLRESR-HDNVI 71
Query: 89 CLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSG----QPLTDAHYQSFIYQILCGLK 144
L D VF N + E ++ D+ ++K QP AH +S++ +L GL
Sbjct: 72 ELVD---VFSTKSNLN---IILEFLDSDLEMLIKDKFIVFQP---AHIKSWMVMLLRGLH 122
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
+IHS +LHRDLKP NLL+++D LK+ DFGL+R + ++ V TRWYR PE
Sbjct: 123 HIHSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFG-----TPSHMSHQVITRWYRPPE 177
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
+ + + Y +D+WS GCI AEL+ P G+ +DQLN I + LGTP E +K +
Sbjct: 178 LFMGCRSYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSM-- 235
Query: 265 KNVQDYIHQLGYI--PKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
+ + +Y+ ++ +I P L+ A + ++LL+ ML ++P R T AL+H Y S
Sbjct: 236 QQLPNYV-EMKHIPPPNGGMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSA 294
Query: 323 WHDPADEPICTEK 335
P + K
Sbjct: 295 LPKPTHPSLLPRK 307
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 162 bits (410), Expect = 1e-39
Identities = 106/300 (35%), Positives = 162/300 (53%), Gaps = 15/300 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ ++++G G+YG V AR E A VA+KK + + +LRE+ +LR
Sbjct: 16 FEKLEKVGEGTYGKVYRAR--EKATGMIVALKKTRLHEDEEGVPPTTLREISILRMLARD 73
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS----GQPLTDAHYQSFIYQIL 140
+I L D+ +G LYL E ++ D+ + ++S GQ + + +YQ+
Sbjct: 74 PHIVRLMDVKQGINKEGK-TVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQLC 132
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRW 199
G+ + H VLHRDLKP NLL++ LKI D GLAR ++ P++ T + T W
Sbjct: 133 KGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTL-PMKK---YTHEILTLW 188
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YRAPE++L Y+ +D+WS GCI AEL+ + IF G + QL RI ++LGTP EE
Sbjct: 189 YRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVW 248
Query: 260 KRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
G ++D+ H+ + ST PN + L+LL ML ++P RI+ A++HPY
Sbjct: 249 P--GVSKLKDW-HEYPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPY 305
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 161 bits (407), Expect = 2e-39
Identities = 109/299 (36%), Positives = 162/299 (53%), Gaps = 17/299 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+ +++IG G+YG V AR + + VA+K+V + +LRE+ +LR + H
Sbjct: 4 YDKMEKIGEGTYGTVFKARNKNSGE--IVALKRVRLDDDDEGVPSSALREICILRELK-H 60
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY-QSFIYQILCGL 143
+N+ LYD +V N L L E + D+ + S DA +S + Q+L GL
Sbjct: 61 RNVVRLYD--VVHSE----NKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGL 114
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+ H+ VLHRDLKP NLL+N + LK+ DFGLAR + PV + + V T WYR P
Sbjct: 115 SFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGV-PV---RCFSAEVVTLWYRPP 170
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELL-GGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
+++ + Y +ID+WS GCI AE+ G+P+F G D DQL RI + LG+P E+ I
Sbjct: 171 DVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSI 230
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
+ DY Y P + +S + PN N +LL+ +L +P RI D AL+H Y +
Sbjct: 231 --TQLPDYKPYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFA 287
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 161 bits (407), Expect = 2e-39
Identities = 107/296 (36%), Positives = 157/296 (52%), Gaps = 21/296 (7%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ + +IG G+Y IV AR E VA+KKV + RE+ +LR H
Sbjct: 141 FEKLDKIGQGTYSIVYKARDLETGK--IVAMKKVRFANMDPESVRFMAREINILRKL-DH 197
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQI-VKSGQPLTDAHYQSFIYQILCGL 143
N+ L + + L+L E ME D+ + ++ G T+ + F+ Q+LCGL
Sbjct: 198 PNVMKLQCL----VTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQIKCFMKQLLCGL 253
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ HS +LHRD+K NLLVN D LKI DFGLA Y + +Q LT V T WYRAP
Sbjct: 254 EHCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKP---DQDQPLTSRVVTLWYRAP 310
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y AID+WS GCILAEL KPI G+ V+Q+++I ++ G+P EE
Sbjct: 311 ELLLGSTEYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEEFW---- 366
Query: 264 SKNVQDYIHQLGYIPKIPFSTL----YPNANPDALNLLEGMLSFDPQLRITVDDAL 315
N + Y P+ P+ + + N + +L+LL+ +LS +P+ R + L
Sbjct: 367 --NTTKFPQATSYKPQHPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTL 420
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 160 bits (405), Expect = 4e-39
Identities = 104/298 (34%), Positives = 161/298 (53%), Gaps = 19/298 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+Q ++++G G+Y V + + + KV + + ++RE+ L++ R H
Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGE---IVALKVIRIDADEGTPSTAIREISLMKELR-H 58
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS---GQPLTDAHYQSFIYQILC 141
NI L D V Q + N L L E ME D+ + + + L + ++F Q+L
Sbjct: 59 PNIMSLSD---VLQTE---NKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLK 112
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+ + H VLHRDLKP NLL+N+ +LK+ DFGLAR + N F E V T WYR
Sbjct: 113 GISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIG---IPVNTFSNE-VVTLWYR 168
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
AP+++L + Y+ +ID+WS GCI+AE+ G+P+F G + DQL +I ++LGTP E++
Sbjct: 169 APDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWP- 227
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
G + +Y + L+P +P L+LL ML P+LR T DALQH +
Sbjct: 228 -GISLLPEYKPTFPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAW 284
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 160 bits (404), Expect = 5e-39
Identities = 112/319 (35%), Positives = 163/319 (50%), Gaps = 20/319 (6%)
Query: 22 DKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHF 81
D++++ + EIG G+YG V AR + VA+K+V + + ++RE+ +LRH
Sbjct: 10 DQQYECVAEIGEGAYGKVFKARDLKNGGRF-VALKRVRVQTGEEGMPLSTIREVAVLRHL 68
Query: 82 RG--HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP-LTDAHYQSFIYQ 138
H N+ L+D+ V + D ++E + + + K +P + + ++Q
Sbjct: 69 ETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 128
Query: 139 ILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATR 198
+L GL ++HS V+HRDLKP N+LV + Q+K+ DFGLAR YS LT V T
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYS-----FQMALTSVVVTL 183
Query: 199 WYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
WYRAPE++L Y +D+WS GCI AE+ KP+F+G VDQL +IL V+G P EE
Sbjct: 184 WYRAPEVLLQ-SSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEED 242
Query: 259 LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHP 318
R + Q + H P F T D LL L+F+P RI+ AL HP
Sbjct: 243 WPRDVALPRQAF-HSKSAQPIEKFVTDIDELGKD---LLLKCLTFNPAKRISAYSALSHP 298
Query: 319 YLSIWHDPADEPICTEKFD 337
Y D C E D
Sbjct: 299 YFQ------DLERCKENLD 311
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 159 bits (401), Expect = 1e-38
Identities = 108/302 (35%), Positives = 157/302 (51%), Gaps = 23/302 (7%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+GHGS+G+V A+ E + TVAIKKV R L+ ++LL H C
Sbjct: 79 VGHGSFGVVFQAKCLETGE--TVAIKKV---LQDRRYKNRELQTMRLLDHPNVVSLKHCF 133
Query: 91 YDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTD----AHYQSFIYQILCGLKYI 146
+ + D ++ L L E + +H+++K L + + + YQI L YI
Sbjct: 134 FSTT---EKDELYLNLVL--EYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYI 188
Query: 147 HSA-DVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
H V HRD+KP NLLVN Q+K+CDFG A+ + E N Y+ +R+YRAPE
Sbjct: 189 HRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKG--EPN---ISYICSRYYRAPE 243
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++ YT AIDVWS GC+LAELL G+P+F G+ VDQL I++VLGTP E +K +
Sbjct: 244 LIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNP 303
Query: 265 KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWH 324
+ Q+ P + P+A++L+ +L + P LR D+L HP+
Sbjct: 304 NYTEFKFPQIKAHPW--HKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELR 361
Query: 325 DP 326
DP
Sbjct: 362 DP 363
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 158 bits (400), Expect = 2e-38
Identities = 97/299 (32%), Positives = 161/299 (53%), Gaps = 20/299 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
FQ +++IG G+YG+V AR E VA+KK+ + ++RE+ LL++ + H
Sbjct: 5 FQKLEKIGEGTYGVVYKAR--ERNTNRVVALKKIRLENENEGIPATTIREILLLKNLK-H 61
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK----SGQPLTDAHYQSFIYQIL 140
I L D+++ N +YL E +E D+ + + G+ + + + Q+L
Sbjct: 62 STIVEL--SDVIYNN----NKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLL 115
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
++Y HS ++ HRDLKP N+LV+ +K+ DFGL R + + TE V T WY
Sbjct: 116 TAMEYCHSRNIFHRDLKPQNILVDPKENIKLADFGLGRAAG---IPLRTYTTE-VVTLWY 171
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
R PE++L + Y ++DVWS CI+AE++ +P F G +DQL RI +VLGTP
Sbjct: 172 RPPELLLGCKYYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWS 231
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ +N +Y + + T++ +PD ++L+ ML +DP++R+T + L H Y
Sbjct: 232 NV--ENFPNYKVEFPVWDPVDLKTIF-RGDPDFVDLISKMLEYDPKMRMTAKNGLSHKY 287
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 157 bits (398), Expect = 3e-38
Identities = 107/300 (35%), Positives = 161/300 (53%), Gaps = 20/300 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++++++I GSYGIV R + + T VA+KK+ + SLRE++ L R H
Sbjct: 74 YEILEKIEEGSYGIVY--RGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIR-H 130
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
NI L +V D +YL E ME D+ ++ + + + ++ + Q+L
Sbjct: 131 DNIVELEK--VVVGKD--LKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAAT 186
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++H LHRDLKP NLL+N ++K+ DFGLAR SE LT V T WYRAP
Sbjct: 187 AFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEP----KSSLTRLVVTLWYRAP 242
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y K ID+WS GCI AE++ P+F GK +DQL +I +LG P E +
Sbjct: 243 ELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQY- 301
Query: 264 SKNVQDYIHQLGYIPKIP----FSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ Y +++ + P +P T PN +A +LL +LS +P RI+ +AL+HPY
Sbjct: 302 --FLLPYANKIKH-PTVPTHSKIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPY 358
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 157 bits (398), Expect = 3e-38
Identities = 108/302 (35%), Positives = 156/302 (50%), Gaps = 23/302 (7%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+GHGS+G+V A+ E + TVAIKKV R L+ ++LL H C
Sbjct: 75 VGHGSFGVVFQAKCLETGE--TVAIKKV---LQDRRYKNRELQTMRLLDHPNVVSLKHCF 129
Query: 91 YDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDA----HYQSFIYQILCGLKYI 146
+ + D ++ L L E + +H+++K L + + + YQI L YI
Sbjct: 130 FSTT---EKDELYLNLVL--EYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYI 184
Query: 147 HSA-DVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
H V HRD+KP NLLVN Q+K+CDFG A+ + E N Y+ +R+YRAPE
Sbjct: 185 HRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKG--EPN---ISYICSRYYRAPE 239
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++ YT AIDVWS GC+LAELL G+P+F G+ VDQL I++VLGTP E +K +
Sbjct: 240 LIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNP 299
Query: 265 KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWH 324
+ Q+ P + P+A++L+ +L + P LR D L HP+
Sbjct: 300 NYTEFKFPQIKAHPW--HKIFHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFDELR 357
Query: 325 DP 326
DP
Sbjct: 358 DP 359
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 157 bits (396), Expect = 5e-38
Identities = 105/304 (34%), Positives = 165/304 (53%), Gaps = 23/304 (7%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ ++++G G+YG V AR E A VA+KK + + +LRE+ +LR
Sbjct: 14 FEKLEKVGEGTYGKVYRAR--EKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLARD 71
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS----GQPLTDAHYQSFIYQIL 140
++ L D+ +G LYL E M+ D+ + ++S G+ + +S +YQ+
Sbjct: 72 PHVVRLMDVKQGLSKEGK-TVLYLVFEYMDTDVKKFIRSFRSTGKNIPTQTIKSLMYQLC 130
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRW 199
G+ + H +LHRDLKP NLL++ +LKI D GLAR ++ P++ T + T W
Sbjct: 131 KGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTL-PMKK---YTHEILTLW 186
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YRAPE++L Y+ A+D+WS GCI AEL+ + IF+G + QL I ++ GTP EE
Sbjct: 187 YRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMW 246
Query: 260 KRIGS-KNVQDYIHQLGYIPKIPFSTL---YPNANPDALNLLEGMLSFDPQLRITVDDAL 315
+ + KN +Y P+ STL PN + ++LL ML ++P RI+ A+
Sbjct: 247 PGVSTLKNWHEY-------PQWKPSTLSSAVPNLDEAGVDLLSKMLQYEPAKRISAKMAM 299
Query: 316 QHPY 319
+HPY
Sbjct: 300 EHPY 303
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 155 bits (392), Expect = 1e-37
Identities = 107/303 (35%), Positives = 161/303 (52%), Gaps = 25/303 (8%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+G GS+GIV A+ E + TVAIKKV + REL+L+R H N+ CL
Sbjct: 46 VGTGSFGIVFQAKCLETGE--TVAIKKVLQDR------RYKNRELQLMR-VMDHPNVVCL 96
Query: 91 -YDMDIVFQPDGMFNGLYLYEELMECDMHQIVK----SGQPLTDAHYQSFIYQILCGLKY 145
+ D +F L L E + +++++K + Q + + + ++YQI GL Y
Sbjct: 97 KHCFFSTTSKDELF--LNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAY 154
Query: 146 IHS-ADVLHRDLKPGNLLVNA-DCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
IH+ A V HRDLKP NLLV+ Q+KICDFG A+ + Y+ +R+YRAP
Sbjct: 155 IHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEAN-----ISYICSRFYRAP 209
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++ YT +ID+WS GC+LAELL G+P+F G++ VDQL I++VLGTP E ++ +
Sbjct: 210 ELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMN 269
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW 323
Q+ P + P+A++ +L + P LR T +A HP+
Sbjct: 270 PHYTDFRFPQIKAHPW--HKIFHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDEL 327
Query: 324 HDP 326
+P
Sbjct: 328 REP 330
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 155 bits (391), Expect = 2e-37
Identities = 102/300 (34%), Positives = 159/300 (53%), Gaps = 21/300 (7%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ + +G GSYGIV AR T + + VA+KKV K L LRE+ +L+ H
Sbjct: 53 FEKLNRVGEGSYGIVYRARDTRSNE--IVALKKVRMDQEKDGLPISGLREIMILKQCH-H 109
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
+NI L ++ + D +F L + E D+ ++ + QP T++ + Q+L L
Sbjct: 110 ENIVRLREVVVGKSLDSIF----LVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKAL 165
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
KY+HS ++HRDLK NLL+ +K+ DFGLAR +S P +T + T WYRAP
Sbjct: 166 KYLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKP----MTPQMVTLWYRAP 221
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L + +T A+D+W+ GCIL ELL GKP+ G + QL+ I+ +LG P E
Sbjct: 222 ELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFA 281
Query: 264 S-KNVQDYIHQLGYIPKIPFSTLYPN---ANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
VQ++ + + P++ L P NLL + ++P+ R T ++ L+ Y
Sbjct: 282 DLPAVQNFT-----LSQQPYNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKY 336
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 154 bits (390), Expect = 2e-37
Identities = 106/316 (33%), Positives = 166/316 (51%), Gaps = 47/316 (14%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKNI 87
K +G GS+G+V E+ ++ AIK+V L KR REL+++R + H NI
Sbjct: 36 KVVGSGSFGVVMQVHLIES--DSKAAIKRV-------LQDKRFKNRELQIMRIMK-HPNI 85
Query: 88 TCLY---------------DMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY 132
L ++ + F P+ ++ LY K P+ +
Sbjct: 86 VDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQ---------KLSMPMLEV-- 134
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFL 191
+ +IYQ+L L YIH++ + HRD+KP NLL++ + LK+CDFG A+ E N
Sbjct: 135 KLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAG--EPN--- 189
Query: 192 TEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVL 251
Y+ +R+YRAPE++ YT AID+WS GC++AEL+ G P+F G+ +DQL I+++L
Sbjct: 190 VSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKIL 249
Query: 252 GTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANP-DALNLLEGMLSFDPQLRIT 310
GTP E +K + ++ H+ I P S ++ + P DAL+LL ML + P R+T
Sbjct: 250 GTPSREQIKTMNPNYME---HRFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLT 306
Query: 311 VDDALQHPYLSIWHDP 326
+A+ HP+ DP
Sbjct: 307 AAEAMCHPFFDELRDP 322
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 154 bits (390), Expect = 2e-37
Identities = 108/308 (35%), Positives = 159/308 (51%), Gaps = 25/308 (8%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F++I +IG G+YG V AR D VA+KKV K ++RE+K+LR H
Sbjct: 804 FEMIAQIGEGTYGQVYKARDHHTND--MVALKKVRLEHEKEGFPITAVREIKILRQLN-H 860
Query: 85 KNITCLYDM------DIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIY 137
+NI L+++ + F+ D YL E M+ D+ +++SG + + S +
Sbjct: 861 RNIVNLHEIVTDKQDAVEFRKDK--GSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMK 918
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVAT 197
Q+L GL Y H + LHRD+K N+L+N ++K+ DFGLAR Y N + + T V T
Sbjct: 919 QLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLY--NADDRERPYTNKVIT 976
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP--- 254
WYR PE++L + Y +IDVWSCGCIL EL +P+F+ + QL I ++ G+P
Sbjct: 977 LWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPA 1036
Query: 255 --PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
P + Q H+ F AL+LL+ ML DP RIT +
Sbjct: 1037 VWPNVIKLPLFHTLKQKKTHRRRLREDFEFMP------APALDLLDKMLDLDPDKRITAE 1090
Query: 313 DALQHPYL 320
DAL+ P+L
Sbjct: 1091 DALRSPWL 1098
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 154 bits (389), Expect = 3e-37
Identities = 101/330 (30%), Positives = 164/330 (49%), Gaps = 38/330 (11%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
++++ I +IG GSYG+V R + VAIKK ++ K +LRE+++L+ +
Sbjct: 3 EKYEKIGKIGEGSYGVVFKCRNRDTGQ--IVAIKKFLESEDDPVIKKIALREIRMLKQLK 60
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECD---MHQIVKSGQPLTDAHYQSFIYQI 139
H N+ L + VF+ + ++ Y CD +H++ + + + + +S +Q
Sbjct: 61 -HPNLVNLLE---VFRRKRRLHLVFEY-----CDHTVLHELDRYQRGVPEHLVKSITWQT 111
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRW 199
L + + H + +HRD+KP N+L+ +K+CDFG AR + + + T+YVATRW
Sbjct: 112 LQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGP----SDYYTDYVATRW 167
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YR+PE+++ Y +DVW+ GC+ AELL G P++ GK VDQL I + LG
Sbjct: 168 YRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQ 227
Query: 260 KRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ + + P +PN + AL LL+G L DP R+T + L HPY
Sbjct: 228 QVFSTNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPY 287
Query: 320 LSIWHDPADEPICTEKFDFSFESVNEIEQL 349
FE++ EIE L
Sbjct: 288 --------------------FENIREIEDL 297
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 153 bits (387), Expect = 5e-37
Identities = 98/293 (33%), Positives = 154/293 (52%), Gaps = 16/293 (5%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
++++G G+Y V R E VA+K++ + C ++RE+ LL+ + H NI
Sbjct: 195 LEKLGEGTYATVYKGR--SKLTENLVALKEIRLEHEEGAPCT-AIREVSLLKDLK-HANI 250
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGLKYI 146
L+D + D L L E ++ D+ Q + G ++ + + F+YQIL GL Y
Sbjct: 251 VTLHD---IVHTD---KSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYC 304
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H VLHRDLKP NLL+N +LK+ DFGLAR S V + E V T WYR P+++
Sbjct: 305 HRRKVLHRDLKPQNLLINEKGELKLADFGLARAKS---VPTKTYSNE-VVTLWYRPPDVL 360
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKN 266
L Y ID+W GCI E+ G+P+F G D+L+ I ++LGTP +ET I S
Sbjct: 361 LGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNE 420
Query: 267 VQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ Y P+ P P + + + L+ L ++ + R++ ++A++H Y
Sbjct: 421 EFKNYNFPKYKPE-PLINHAPRLDSEGIELIRKFLQYESKKRVSAEEAMKHVY 472
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 153 bits (387), Expect = 5e-37
Identities = 106/307 (34%), Positives = 161/307 (51%), Gaps = 31/307 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
K F+ + IG G+YGIV AR T+ + VA+KKV K + SLRE+ LL R
Sbjct: 37 KEFEKLNRIGEGTYGIVYRARDTQT--DEIVALKKVRMDKEKDGIPISSLREITLLLRLR 94
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI L ++ + ++L E D+ ++++ P ++A + + Q+L
Sbjct: 95 -HPNIVELKEVVV----GNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLR 149
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
GL+Y+H ++HRDLK NLL+ +K DFGLAR Y PV+ +T V T WYR
Sbjct: 150 GLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGV-PVKP---MTPKVVTLWYR 205
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPE----- 256
APE++L T +ID+W+ GCILAELL +P+ G + Q++ I+Q+LGTP E
Sbjct: 206 APELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPG 265
Query: 257 -ETLKRIGSKNVQDYIHQLGYIPKIPFSTL---YPNANPDALNLLEGMLSFDPQLRITVD 312
L +G +++ K P++ L +P + L LL + +DP+ R T
Sbjct: 266 FSKLPLVGQYSLR----------KQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAG 315
Query: 313 DALQHPY 319
D L+ Y
Sbjct: 316 DCLESSY 322
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 153 bits (387), Expect = 5e-37
Identities = 106/307 (34%), Positives = 161/307 (51%), Gaps = 31/307 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
K F+ + IG G+YGIV AR T+ + VA+KKV K + SLRE+ LL R
Sbjct: 8 KEFEKLNRIGEGTYGIVYRARDTQT--DEIVALKKVRMDKEKDGIPISSLREITLLLRLR 65
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI L ++ + ++L E D+ ++++ P ++A + + Q+L
Sbjct: 66 -HPNIVELKEVVV----GNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLR 120
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
GL+Y+H ++HRDLK NLL+ +K DFGLAR Y PV+ +T V T WYR
Sbjct: 121 GLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGV-PVKP---MTPKVVTLWYR 176
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPE----- 256
APE++L T +ID+W+ GCILAELL +P+ G + Q++ I+Q+LGTP E
Sbjct: 177 APELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPG 236
Query: 257 -ETLKRIGSKNVQDYIHQLGYIPKIPFSTL---YPNANPDALNLLEGMLSFDPQLRITVD 312
L +G +++ K P++ L +P + L LL + +DP+ R T
Sbjct: 237 FSKLPLVGQYSLR----------KQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAG 286
Query: 313 DALQHPY 319
D L+ Y
Sbjct: 287 DCLESSY 293
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 153 bits (386), Expect = 7e-37
Identities = 107/324 (33%), Positives = 176/324 (54%), Gaps = 45/324 (13%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETT---VAIKKVTNVFSKTLLCKRSLRELKLLRH 80
+F+ ++++G+G+Y V + ++TT VA+K+V + S+ ++RE+ L++
Sbjct: 6 QFKQLEKLGNGTYATVY-----KGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKE 59
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS--------GQPLTDAHY 132
+ H+NI LYD V + N L L E M+ D+ + + S G L Y
Sbjct: 60 LK-HENIVRLYD---VIHTE---NKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKY 112
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLT 192
F +Q+L GL + H +LHRDLKP NLL+N QLK+ DFGLAR + + N F +
Sbjct: 113 --FQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFG---IPVNTFSS 167
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
E V T WYRAP++++ + Y+ +ID+WSCGCILAE++ GKP+F G + +QL I ++G
Sbjct: 168 E-VVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMG 226
Query: 253 TPPEETLKRIG-----SKNVQDYIHQLGYIPKIPFSTLYPNA----NPDALNLLEGMLSF 303
TP E + + N+Q P+ L P+ + + ++ L G+L
Sbjct: 227 TPNESLWPSVTKLPKYNPNIQQ------RPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQL 280
Query: 304 DPQLRITVDDALQHPYLSIWHDPA 327
+P +R++ AL HP+ + ++ A
Sbjct: 281 NPDMRLSAKQALHHPWFAEYYHHA 304
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 153 bits (386), Expect = 7e-37
Identities = 99/322 (30%), Positives = 170/322 (52%), Gaps = 28/322 (8%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+ L++++G G++G V ++ D A+K++ K ++RE+K+L+ + H
Sbjct: 36 YHLMEKLGEGTFGEVYKSQ--RRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIK-H 92
Query: 85 KNITCLYDMDIVF--QPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILC 141
+NI L DM +V + +Y+ M+ D+ ++++ T+ + ++ Q+
Sbjct: 93 ENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFA 152
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSEN---------PVENNQFLT 192
G KY+H +LHRDLK NLL++ LKI DFGLAR +E P N + T
Sbjct: 153 GTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREYT 212
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
V TRWYR+PE++L + YT AID+WS GCI+AE+ G+PI +G +DQL++I ++ G
Sbjct: 213 GCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCG 272
Query: 253 TPPEETL----KRIGSKNVQDYIHQLGYIPKIP--FSTLYPNANPDALNLLEGMLSFDPQ 306
+P + T+ K G + V+ + P P T + + +L +L+ +P
Sbjct: 273 SPTQATMPNWEKLPGCEGVRSF-------PSHPRTLETAFFTFGKEMTSLCGAILTLNPD 325
Query: 307 LRITVDDALQHPYLSIWHDPAD 328
R++ AL+H Y + PA+
Sbjct: 326 ERLSASMALEHEYFTTPPYPAN 347
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 153 bits (386), Expect = 7e-37
Identities = 105/299 (35%), Positives = 154/299 (51%), Gaps = 13/299 (4%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ + +IG G+Y V AR E VA+KKV V + RE+ +LR H
Sbjct: 156 FEKLDKIGQGTYSSVYRARDLETGK--MVAMKKVRFVNMDPESVRFMAREINILRKL-DH 212
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQI-VKSGQPLTDAHYQSFIYQILCGL 143
N+ L + + LYL E ME D+ + ++ G T++ + ++ Q+L GL
Sbjct: 213 PNVMKLECL----VTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQIKCYMKQLLSGL 268
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ HS +LHRD+K NLLVN D LKI DFGLA Y E +Q LT V T WYRAP
Sbjct: 269 EHCHSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHP---EQDQPLTSRVVTLWYRAP 325
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y ID+WS GCIL EL GKPI G+ V+Q+++I + G+P ++ ++
Sbjct: 326 ELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSDDYWQKTK 385
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
+ Q Y K + N P AL L++ +LS +P R T L + ++
Sbjct: 386 LPLATSFKPQQPY--KRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTLSSKFFTM 442
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 153 bits (386), Expect = 7e-37
Identities = 126/426 (29%), Positives = 201/426 (46%), Gaps = 40/426 (9%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ +++IG G+Y V AR E VA+KKV + RE+ +LR H
Sbjct: 163 FEKLEKIGQGTYSSVYKARDLET--NQLVALKKVRFANMDPDSVRFMAREIIILRRL-DH 219
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
N+ L + I + G +YL E ME D+ + + G ++A + ++ Q+L GL
Sbjct: 220 PNVMKLEGL-ITSRVSG---SMYLIFEYMEHDLAGLASTPGINFSEAQIKCYMKQLLHGL 275
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ HS VLHRD+K NLL++ + LKI DFGLA Y + Q LT V T WYR P
Sbjct: 276 EHCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQGH---QKQPLTSRVVTLWYRPP 332
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y +D+WS GCILAEL GKPI G+ V+QL++I ++ G+P EE K
Sbjct: 333 ELLLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEEYWK--- 389
Query: 264 SKNVQDYIHQLGYIPKIPF----STLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ H + P+ P+ + + + AL L+E +L+ +P R T AL+ +
Sbjct: 390 ---ISKLPHATIFKPQQPYKRCVAETFKSLPSSALALVEVLLAVEPDARGTTASALESEF 446
Query: 320 LS---IWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVR----------- 365
+ + DP+ P + + ++ E + K+ + D +Q R
Sbjct: 447 FTTSPLASDPSSLPKYQPRKEIDVKAQEEEAKRKKDTSSKQNDSKQVSRESKAVPAPDSN 506
Query: 366 ---LPLLHEQQQQQGKTDGGFDDQIREDQRTFQAQ--LEEQVNNGRTASNVPSFDEPFSS 420
L + ++Q Q + ED +F+ + +G T V S + +
Sbjct: 507 AESLTSIQKRQGQHNQVSNSDKFNPGEDAASFRIEPLKSGTAKDGHTRYGVSSVNRNGEN 566
Query: 421 QMMGSA 426
MMGS+
Sbjct: 567 VMMGSS 572
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 152 bits (385), Expect = 9e-37
Identities = 111/309 (35%), Positives = 169/309 (53%), Gaps = 21/309 (6%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
VDK F +I IG G+YG V AR + + VA+KKV K ++RE+K+LR
Sbjct: 724 VDK-FDIIGIIGEGTYGQVYKARDKDTGE--LVALKKVRLDNEKEGFPITAIREIKILRQ 780
Query: 81 FRGHKNITCLYDMDIVFQPDGMF-----NGLYLYEELMECDMHQIVKSGQP-LTDAHYQS 134
H+++ + ++ + + D + YL E M+ D+ +++SG ++ H +S
Sbjct: 781 LI-HRSVVNMKEI-VTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKS 838
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
F+ Q++ GL+Y H + LHRD+K N+L+N Q+K+ DFGLAR Y+ E ++ T
Sbjct: 839 FMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNS---EESRPYTNK 895
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
V T WYR PE++L + YT AIDVWSCGCIL EL KPIF+ + QL I ++ G+P
Sbjct: 896 VITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSP 955
Query: 255 PEET---LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITV 311
+ ++ N Q + FS + P+A AL+LL+ ML+ DP R T
Sbjct: 956 CPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFI-PSA---ALDLLDHMLTLDPSKRCTA 1011
Query: 312 DDALQHPYL 320
+ LQ +L
Sbjct: 1012 EQTLQSDFL 1020
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 152 bits (385), Expect = 9e-37
Identities = 109/331 (32%), Positives = 165/331 (48%), Gaps = 33/331 (9%)
Query: 22 DKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHF 81
+ F+ ++IG G++ V AR + TVA+K++ + + K RE+ +LR
Sbjct: 100 ESHFEKQEQIGGGTFSKVFKAR--DLLRNKTVALKRIRFDINNSESIKCIAREIIILRKL 157
Query: 82 RGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQIL 140
H N+ L + +V D + LYL E ME D+ + G ++ + ++ Q+L
Sbjct: 158 -DHPNVIKLEGLMLV---DHDSSTLYLIFEYMEHDLLGLSSLLGVHFSEPQVKCYMRQLL 213
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GL + H+ VLHRD+K NLL+N D LKI DFGLA + + N+ LT +VAT WY
Sbjct: 214 RGLDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLATFFDPH---NSVPLTTHVATLWY 270
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
R PE++L Y +D+WS GC++ EL GKPI GK+ DQL++I ++ G+P +
Sbjct: 271 RPPELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSD---- 326
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRIT 310
DY +L P +YP + ++LLE +LS DP R T
Sbjct: 327 --------DYWTKLKLQLSTPLRPIYPYGSHIAETFKQFPASVISLLETLLSIDPDFRGT 378
Query: 311 VDDALQHPYLSIWHDPADEPICTEKFDFSFE 341
AL+ Y A +P C K+ S E
Sbjct: 379 AASALKSKYFKT-EPLACDPSCLPKYPSSKE 408
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 152 bits (385), Expect = 9e-37
Identities = 108/303 (35%), Positives = 158/303 (51%), Gaps = 25/303 (8%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKNITC 89
+G GS+G+V A+ E ++ VAIKKV L KR REL+++R + H N+
Sbjct: 144 VGTGSFGVVFQAKCLETGEQ--VAIKKV-------LQDKRYKNRELQIMR-LQDHPNVVR 193
Query: 90 L-YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKY 145
L + D ++ L Y+ E + H K Q + Q + YQI L Y
Sbjct: 194 LRHSFFSTTDKDELYLNLVLEYVPETVYRASKHY-TKMNQHMPIIFVQLYTYQICRALNY 252
Query: 146 IHSA-DVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+H V HRD+KP NLLVN QLKICDFG A+ P E N Y+ +R+YRAP
Sbjct: 253 LHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLV--PGEPN---ISYICSRYYRAP 307
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++ YT AID+WS GC++AELL G+P+F G+ +DQL I+++LGTP E ++ +
Sbjct: 308 ELIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTREEIRCMN 367
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW 323
+ Q+ P + P+A++L+ +L + P LR T +A HP+
Sbjct: 368 PNYTEFKFPQIKAHPW--HKIFHKRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFFDDL 425
Query: 324 HDP 326
DP
Sbjct: 426 RDP 428
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 152 bits (385), Expect = 9e-37
Identities = 101/300 (33%), Positives = 162/300 (53%), Gaps = 14/300 (4%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ I +IG G+Y V A+ ++ VA+KKV ++ K RE+ +LR H
Sbjct: 138 FEKIDKIGSGTYSNVYKAK--DSLTGNIVALKKVRCDVNERESLKFMAREILILRRL-DH 194
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCGL 143
N+ L + M + LYL M+ D+ + S + T+ + ++ Q+L GL
Sbjct: 195 PNVIKLEGL----VTSRMSSSLYLVFRYMDHDLAGLAASPEIKFTEQQVKCYMKQLLSGL 250
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ H+ VLHRD+K NLL++ L+I DFGLA + + Q +T V T WYR+P
Sbjct: 251 EHCHNRGVLHRDIKGSNLLIDDGGVLRIGDFGLATFFDAS---KRQEMTNRVVTLWYRSP 307
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++ Y+ +D+WS GCILAELL G+ I G++ V+QL+RI ++ G+P EE K+I
Sbjct: 308 ELLHGVVEYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIR 367
Query: 264 SKNVQDYIHQLGYIP--KIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
+ + H +P K +Y + +P+AL+LL+ +L+ DP R T D L + +
Sbjct: 368 LPSTHKHAHHKP-LPQYKRRIREVYKDFSPEALSLLDTLLALDPAERQTATDVLMSDFFT 426
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 152 bits (384), Expect = 1e-36
Identities = 113/319 (35%), Positives = 165/319 (51%), Gaps = 41/319 (12%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
VDK F +I IG G+YG V AR + + VA+KKV K ++RE+K+LR
Sbjct: 702 VDK-FDIIGIIGEGTYGQVYKARDKDTGE--MVALKKVRLDNEKEGFPITAIREIKILRQ 758
Query: 81 FRGHKNITCLYDMDIVFQPDGMF-----NGLYLYEELMECDMHQIVKSGQP-LTDAHYQS 134
H++I + ++ + + D + YL E M+ D+ +++SG + H +S
Sbjct: 759 LT-HQSIINMKEI-VTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKS 816
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
F+ Q++ GL Y H + LHRD+K N+L+N Q+K+ DFGLAR YS E ++ T
Sbjct: 817 FMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSS---EESRPYTNK 873
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
V T WYR PE++L + YT AIDVWSCGCIL EL KPIF+ + QL I ++ G+P
Sbjct: 874 VITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSP 933
Query: 255 PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNAN-------------PDALNLLEGML 301
V + +L Y F+T+ P AL+L + ML
Sbjct: 934 ---------CPAVWPDVIKLPY-----FNTMKPKKQYRRKLREEFVFIPAAALDLFDYML 979
Query: 302 SFDPQLRITVDDALQHPYL 320
+ DP R T + ALQ +L
Sbjct: 980 ALDPSKRCTAEQALQCEFL 998
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 152 bits (384), Expect = 1e-36
Identities = 113/319 (35%), Positives = 165/319 (51%), Gaps = 41/319 (12%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
VDK F +I IG G+YG V AR + + VA+KKV K ++RE+K+LR
Sbjct: 702 VDK-FDIIGIIGEGTYGQVYKARDKDTGE--MVALKKVRLDNEKEGFPITAIREIKILRQ 758
Query: 81 FRGHKNITCLYDMDIVFQPDGMF-----NGLYLYEELMECDMHQIVKSGQP-LTDAHYQS 134
H++I + ++ + + D + YL E M+ D+ +++SG + H +S
Sbjct: 759 LT-HQSIINMKEI-VTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKS 816
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
F+ Q++ GL Y H + LHRD+K N+L+N Q+K+ DFGLAR YS E ++ T
Sbjct: 817 FMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSS---EESRPYTNK 873
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
V T WYR PE++L + YT AIDVWSCGCIL EL KPIF+ + QL I ++ G+P
Sbjct: 874 VITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSP 933
Query: 255 PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNAN-------------PDALNLLEGML 301
V + +L Y F+T+ P AL+L + ML
Sbjct: 934 ---------CPAVWPDVIKLPY-----FNTMKPKKQYRRKLREEFVFIPAAALDLFDYML 979
Query: 302 SFDPQLRITVDDALQHPYL 320
+ DP R T + ALQ +L
Sbjct: 980 ALDPSKRCTAEQALQCEFL 998
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 152 bits (383), Expect = 1e-36
Identities = 98/314 (31%), Positives = 160/314 (50%), Gaps = 30/314 (9%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
RF ++ IG G+YG+V A D A+K + + + LRE+ ++ +
Sbjct: 44 RFCSLRRIGEGTYGVVFKA--IHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQ- 100
Query: 84 HKNITCLYDM----------DIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP----LTD 129
H NI L+D+ +I F+ + LY+ E ++ D+ +++ +P L
Sbjct: 101 HDNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLPP 160
Query: 130 AHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQ 189
+ +SF++Q+L L Y H ++HRDLKP N+LV+ +KI DFGLAR +S P N
Sbjct: 161 NYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFSF-PSRN-- 217
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
T V T WYR PEI+L Q Y+ ++D+WS GCI +E+ KP+F G+ + QL +I +
Sbjct: 218 -YTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFE 276
Query: 250 VLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANP----DALNLLEGMLSFDP 305
++GTP ++ V + H P+ P + + L++L +L + P
Sbjct: 277 IVGTPNIKSW-----PGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDVLREILRYPP 331
Query: 306 QLRITVDDALQHPY 319
+ R+T AL H Y
Sbjct: 332 ERRLTAKGALSHRY 345
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 151 bits (382), Expect = 2e-36
Identities = 104/300 (34%), Positives = 160/300 (52%), Gaps = 21/300 (7%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ +++IG G+Y V AR + VA+KKV + K RE+ ++R H
Sbjct: 213 FEKLEKIGQGTYSSVYRAR--DLLHNKIVALKKVRFDLNDMESVKFMAREIIVMRRL-DH 269
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK-SGQPLTDAHYQSFIYQILCGL 143
N+ L + + P + + LYL E M+ D+ + G T+ + ++ Q+L GL
Sbjct: 270 PNVLKLEGL--ITAP--VSSSLYLVFEYMDHDLLGLSSLPGVKFTEPQVKCYMRQLLSGL 325
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ HS VLHRD+K NLL+++ LKI DFGLA + +P ++ LT +V T WYR P
Sbjct: 326 EHCHSRGVLHRDIKGSNLLIDSKGVLKIADFGLATFF--DPAKSVS-LTSHVVTLWYRPP 382
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y +D+WS GCIL EL GKPI GK V+QL++I ++ G+P E ++
Sbjct: 383 ELLLGASHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPTENYWRK-- 440
Query: 264 SKNVQDYIHQLGYIPKIPF----STLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
Q G+ IP+ S ++ + L+LLE +LS DP R + D AL+ Y
Sbjct: 441 ----QKLPSSAGFKTAIPYRRKVSEMFKDFPASVLSLLETLLSIDPDHRSSADRALESEY 496
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 151 bits (381), Expect = 2e-36
Identities = 137/465 (29%), Positives = 209/465 (44%), Gaps = 75/465 (16%)
Query: 11 TFKVFNQDFTVDKRFQLIK----------EIGHGSYGIVCSARFTEAADETTVAIKKVTN 60
TF + DF + + + K ++G G+YG V A++ E +D A+K++
Sbjct: 74 TFVKMDYDFKMKTQIERTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQIDG 133
Query: 61 VFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQI 120
T L + RE+ LLR + H+N+ L + + +F L + E D+ I
Sbjct: 134 ----TGLSMSACREIALLRELK-HQNVITLIRVFLSHNDRKVF----LLIDYAEHDLWHI 184
Query: 121 VKSGQPLTDAHYQ---------SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADC---- 167
+K + Q S +YQIL G+ Y+HS VLHRDLKP N+LV D
Sbjct: 185 IKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERG 244
Query: 168 QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAE 227
++KI D G AR ++ P++ L V T WYRAPE++L + YTKAID+W+ GCI AE
Sbjct: 245 RVKIADMGFARLFNA-PLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAE 303
Query: 228 LLGGKPIFKGKD---------YVDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIP 278
LL +PIF + + DQL+RI V+G P ++ + I K + ++
Sbjct: 304 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDI--KKMPEHHTLTKDFK 361
Query: 279 KIPFSTL-------YPNANPD--ALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPADE 329
+ +ST PD A +LL+ +L DP RIT + A+Q Y P +
Sbjct: 362 RSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQD 421
Query: 330 -----PICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPLLHEQQQQQGKTDGGFD 384
PI K +F + E D+ + RQ +QQQQQ +
Sbjct: 422 VFAGCPIPYPKREFLTDDDQE---------DKSDNKRQ--------QQQQQQQQQQQQQQ 464
Query: 385 DQIREDQRTFQAQLEEQVNNGRTASNVPSFDEPFSSQMMGSASQQ 429
Q ++ Q+ Q Q+ + N R + + F Q QQ
Sbjct: 465 QQQQQQQQQQQQQMNAEPNAKRVRLSGAGNQQDFHHQQQQQQQQQ 509
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 150 bits (380), Expect = 3e-36
Identities = 108/325 (33%), Positives = 169/325 (51%), Gaps = 37/325 (11%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKK-------VTNVFSKTLLCKRSLRELKL 77
+++I I G+YG V A + + D+ AIKK V++ +T + + ++RE+ L
Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMML 64
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEE---LMECDMHQIVKSGQPLTDAHYQS 134
R + H+NI L V DG + ++ Y E L H ++ Q + + +S
Sbjct: 65 CREIQ-HENIVSLVQ---VLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQ-IPPSILKS 119
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
++QI+ G+ Y+H ++HRDLKP N+++ A ++KI D GL R +P+
Sbjct: 120 ILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGR-LIRDPILPFYSSDRV 178
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKD-----------YVDQ 243
V T WYRAPE++L YT AIDVW+ GCI E+L P+FKG + Q
Sbjct: 179 VVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQSTQ 238
Query: 244 LNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYP-------NANPDALNL 296
+ RI+++LGTP EE + G KN +Y +QL ++ L P N +P L+L
Sbjct: 239 MLRIMELLGTPTEE--RWPGLKNYPEY-YQLSSFEVRYWNNLLPQWYQTVKNRDPQGLDL 295
Query: 297 LEGMLSFDPQLRITVDDALQHPYLS 321
L ML +DP+ RIT AL+H + +
Sbjct: 296 LMKMLQYDPKSRITAKQALEHVFFT 320
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 150 bits (380), Expect = 3e-36
Identities = 109/306 (35%), Positives = 163/306 (52%), Gaps = 27/306 (8%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKNI 87
K IG+GS+G+V A+ ++ + VAIKKV L KR REL+++R H NI
Sbjct: 60 KVIGNGSFGVVYQAKLCDSGE--LVAIKKV-------LQDKRFKNRELQIMRKL-DHCNI 109
Query: 88 TCL--YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
L + + D ++ L Y+ E + H ++ Q L + + ++YQ+
Sbjct: 110 VRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYS-RAKQTLPVIYVKLYMYQLFRS 168
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
L YIHS + HRD+KP NLL++ D LK+CDFG A+ E N Y+ +R+YR
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN---VSYICSRYYR 223
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++ YT +IDVWS GC+LAELL G+PIF G VDQL I++VLGTP E ++
Sbjct: 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLY-PNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
+ + Q I P++ ++ P P+A+ L +L + P R+T +A H +
Sbjct: 284 MNPNYTEFKFPQ---IKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF 340
Query: 321 SIWHDP 326
DP
Sbjct: 341 DELRDP 346
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 150 bits (379), Expect = 4e-36
Identities = 105/308 (34%), Positives = 161/308 (52%), Gaps = 31/308 (10%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F +++IG G+YG+V + VA+KK+ + ++RE+ LL+ + H
Sbjct: 22 FTKLEKIGEGTYGVVYKGK--NRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQ-H 78
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS---GQPLTDAHYQSFIYQILC 141
N+ L ++ Q N L+L E + D+ + + + L +S+ +QIL
Sbjct: 79 PNVVGLEA--VIMQE----NRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQ 132
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
+ + H V+HRDLKP NLLV+ + +K+ DFGLAR P+ + T V T WYR
Sbjct: 133 AMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGI-PI---RVYTHEVVTLWYR 188
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APEI++ Q Y+ +D+WS GCI AE+ KP+F+G +D+L RI +VLGTP E L+
Sbjct: 189 APEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTE--LEW 246
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPN----------ANPDALNLLEGMLSFDPQLRITV 311
G +++ DY PK + L + A +LLEG+L +DP LR+
Sbjct: 247 NGVESLPDY---KATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNA 303
Query: 312 DDALQHPY 319
AL HPY
Sbjct: 304 KKALVHPY 311
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 150 bits (379), Expect = 4e-36
Identities = 109/303 (35%), Positives = 160/303 (51%), Gaps = 25/303 (8%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+G GS+GIV A+ E + +VAIKKV + REL+L+R H N+ L
Sbjct: 78 VGTGSFGIVFQAKCLETGE--SVAIKKVLQDR------RYKNRELQLMR-LMDHPNVVSL 128
Query: 91 -YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYI 146
+ D +F L Y+ E L H S Q + + + + YQI GL YI
Sbjct: 129 KHCFFSTTTRDELFLNLVMEYVPETLYRVLKHY-TSSNQRMPIFYVKLYTYQIFRGLAYI 187
Query: 147 HSAD-VLHRDLKPGNLLVNA-DCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
H+A V HRD+KP NLLV+ Q K+CDFG A+ + Y+ +R+YRAPE
Sbjct: 188 HTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLVKGEAN-----ISYICSRYYRAPE 242
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++ YT +ID+WS GC+LAELL G+P+F G++ VDQL I++VLGTP E + R +
Sbjct: 243 LIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEI-RCMN 301
Query: 265 KNVQDYIHQLGYIPKIPF-STLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW 323
N D+ + I P+ + P+A++L +L + P LR T +A HP+ +
Sbjct: 302 PNYTDF--RFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNEL 359
Query: 324 HDP 326
+P
Sbjct: 360 REP 362
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 150 bits (378), Expect = 6e-36
Identities = 124/422 (29%), Positives = 196/422 (46%), Gaps = 28/422 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ +++IG G+Y V AR TE VA+KKV + + RE+ +LR H
Sbjct: 131 FEKLEKIGQGTYSSVFRARETETG--RIVALKKVRFDNFEPESVRFMAREILILRKLN-H 187
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCGL 143
NI L + + ++L E ME D+ ++ S T + ++ Q+L GL
Sbjct: 188 PNIIKLEGI----VTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQIKCYMKQLLSGL 243
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+ H+ V+HRD+K NLLVN + LK+ DFGLA N N Q LT V T WYR P
Sbjct: 244 DHCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFC--NASGNKQPLTSRVVTLWYRPP 301
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y ++D+WS GC+ AELL GKP+ +G+ V+QL++I ++ G+PPE+ K+
Sbjct: 302 ELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPEDYWKKSK 361
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS-- 321
+ + Q Y + + + +NL+E +LS P R T AL Y +
Sbjct: 362 LPHAMLFKPQQHYDGCLRETLKLKGLSDADINLIETLLSIQPHKRGTASTALVSQYFTSK 421
Query: 322 -IWHDPADEPICTEKFDFSFESVNEIEQLKQMVID-EVTDFRQYVRLP-----------L 368
DP+ P+ + + + + + K T+ R+ R P +
Sbjct: 422 PFACDPSSLPVYSPSKEIDAKHREDTTRKKISGNGRRGTESRKPTRKPPAFAKLAPAEDV 481
Query: 369 LHEQQQQQGKTDGGFDDQIREDQRTFQAQLEEQVNNGRTASNVPSF---DEPFSSQMMGS 425
H Q+ Q + + I D F+ + + AS+V + D PFS + S
Sbjct: 482 RHHSQKFQKRNGHSVHNSIDSDSTLFEKMQKPSNHEKDEASHVKNASQGDVPFSGPLQVS 541
Query: 426 AS 427
S
Sbjct: 542 VS 543
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 149 bits (376), Expect = 9e-36
Identities = 101/301 (33%), Positives = 153/301 (50%), Gaps = 24/301 (7%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F + +GHGS+G+V + E ++ VAIKKV R L +K+L H
Sbjct: 39 FPTTEVVGHGSFGVVFATVIQETNEK--VAIKKV---LQDKRFKNRELEIMKMLSHINII 93
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQ----IVKSGQPLTDAHYQSFIYQIL 140
Y+ D D ++ L L E M ++Q V P++ + +++Q+
Sbjct: 94 DLKYFFYERD---SQDEIYLNLIL--EYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLF 148
Query: 141 CGLKYIHS-ADVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATR 198
L Y+H A+V HRD+KP NLLV+ + LK+CDFG A+ P E N Y+ +R
Sbjct: 149 KSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLK--PTEPN---VSYICSR 203
Query: 199 WYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
+YRAPE++ YT ID+WS GC++AELL G+P+F G+ +DQL I+++LGTP ++
Sbjct: 204 YYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQ- 262
Query: 259 LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHP 318
I S N H+ I IP S ++ + + L +L +DP R L P
Sbjct: 263 --EICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSP 320
Query: 319 Y 319
Y
Sbjct: 321 Y 321
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 149 bits (376), Expect = 9e-36
Identities = 102/327 (31%), Positives = 176/327 (53%), Gaps = 32/327 (9%)
Query: 20 TVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLR 79
++D+ + +++++G G++G V A T+ + VAIK + +K R LRE+ L
Sbjct: 31 SIDEVYNVVRKVGDGTFGSVYLAT-TKTPSKEVVAIKSMKKKLAKVSDATR-LREVHSLL 88
Query: 80 HFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV--KSGQPLTDAHYQSFIY 137
++NI ++D+ I F L++ E ++C+++Q++ + PLT Q +
Sbjct: 89 RLSENENIVNIFDLYI-----DQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMR 143
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQ-----LKICDFGLARGYSENPVENNQFLT 192
QI GL +IH+ HRD+KP N+L++++ +KI DFGLAR + P T
Sbjct: 144 QIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPP-----YT 198
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
EYV+TRWYRAPE++L Y+ +D+++ GC+ E+ +PIF G D DQL ++ ++LG
Sbjct: 199 EYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILG 258
Query: 253 TPPEETLKRIGSK------NVQDYIHQLGY-IPK---IPFSTLY-PNANPDALNLLEGML 301
+P E++ + G K + ++LG +PK + F L+ P N ++L +L
Sbjct: 259 SPDEQS-QNTGDKGGGIWDRAELLANKLGISLPKMAPLDFGDLFSPPWNLAFASMLSQLL 317
Query: 302 SFDPQLRITVDDALQHPYLSIWHDPAD 328
+DP R T + L + + PAD
Sbjct: 318 KWDPAKRPTAEMCLDLEFCRV-SAPAD 343
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 149 bits (376), Expect = 9e-36
Identities = 109/300 (36%), Positives = 160/300 (53%), Gaps = 27/300 (9%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKN 86
IK IG+GS+G+V AR E + VAIKKV L KR REL+++R H N
Sbjct: 122 IKVIGNGSFGVVYQARLAETRE--LVAIKKV-------LQDKRFKNRELQIMRKL-DHCN 171
Query: 87 ITCL--YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILC 141
I L + + D ++ L Y+ E + H K+ + + + ++YQ+
Sbjct: 172 IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARH-FTKAKLTIPILYVKVYMYQLFR 230
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWY 200
L YIHS V HRD+KP NLLV+ D LK+CDFG A+ E N Y+ +R+Y
Sbjct: 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRG--EPN---VSYICSRYY 285
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPE++ YT +IDVWS GC+LAELL G+PIF G VDQL I++VLGTP E ++
Sbjct: 286 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIR 345
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNAN-PDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ + Q I P++ ++ + P+A+ L +L + P R++ +A H +
Sbjct: 346 EMNPNYTEFKFPQ---IKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSF 402
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 149 bits (376), Expect = 9e-36
Identities = 109/300 (36%), Positives = 160/300 (53%), Gaps = 27/300 (9%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKN 86
IK IG+GS+G+V AR E + VAIKKV L KR REL+++R H N
Sbjct: 122 IKVIGNGSFGVVYQARLAETRE--LVAIKKV-------LQDKRFKNRELQIMRKL-DHCN 171
Query: 87 ITCL--YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILC 141
I L + + D ++ L Y+ E + H K+ + + + ++YQ+
Sbjct: 172 IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARH-FTKAKLTIPILYVKVYMYQLFR 230
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWY 200
L YIHS V HRD+KP NLLV+ D LK+CDFG A+ E N Y+ +R+Y
Sbjct: 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRG--EPN---VSYICSRYY 285
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPE++ YT +IDVWS GC+LAELL G+PIF G VDQL I++VLGTP E ++
Sbjct: 286 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIR 345
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNAN-PDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ + Q I P++ ++ + P+A+ L +L + P R++ +A H +
Sbjct: 346 EMNPNYTEFKFPQ---IKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSF 402
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 149 bits (375), Expect = 1e-35
Identities = 98/293 (33%), Positives = 154/293 (52%), Gaps = 16/293 (5%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
+ ++G G+Y V + + VA+K++ + C ++RE+ LL+ + H NI
Sbjct: 168 LDKLGEGTYATVYKGK--SKLTDNLVALKEIRLEHEEGAPCT-AIREVSLLKDLK-HANI 223
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAH-YQSFIYQILCGLKYI 146
L+D+ + L L E ++ D+ Q + + + H + F++Q+L GL Y
Sbjct: 224 VTLHDIIHTEK------SLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYC 277
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H VLHRDLKP NLL+N +LK+ DFGLAR S + + E V T WYR P+I+
Sbjct: 278 HRQKVLHRDLKPQNLLINERGELKLADFGLARAKS---IPTKTYSNE-VVTLWYRPPDIL 333
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKN 266
L Y+ ID+W GCI E+ G+P+F G +QL+ I ++LGTP EET I S
Sbjct: 334 LGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNE 393
Query: 267 VQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ Y + S P + D +LL +L F+ + RI+ +DA++HP+
Sbjct: 394 EFKTYNYPKYRAEALLSHA-PRLDSDGADLLTKLLQFEGRNRISAEDAMKHPF 445
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 149 bits (375), Expect = 1e-35
Identities = 98/293 (33%), Positives = 154/293 (52%), Gaps = 16/293 (5%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
+ ++G G+Y V + + VA+K++ + C ++RE+ LL+ + H NI
Sbjct: 120 LDKLGEGTYATVYKGK--SKLTDNLVALKEIRLEHEEGAPCT-AIREVSLLKDLK-HANI 175
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAH-YQSFIYQILCGLKYI 146
L+D+ + L L E ++ D+ Q + + + H + F++Q+L GL Y
Sbjct: 176 VTLHDIIHTEK------SLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYC 229
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H VLHRDLKP NLL+N +LK+ DFGLAR S + + E V T WYR P+I+
Sbjct: 230 HRQKVLHRDLKPQNLLINERGELKLADFGLARAKS---IPTKTYSNE-VVTLWYRPPDIL 285
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKN 266
L Y+ ID+W GCI E+ G+P+F G +QL+ I ++LGTP EET I S
Sbjct: 286 LGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNE 345
Query: 267 VQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ Y + S P + D +LL +L F+ + RI+ +DA++HP+
Sbjct: 346 EFKTYNYPKYRAEALLSHA-PRLDSDGADLLTKLLQFEGRNRISAEDAMKHPF 397
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 149 bits (375), Expect = 1e-35
Identities = 111/317 (35%), Positives = 165/317 (52%), Gaps = 27/317 (8%)
Query: 17 QDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLREL 75
+D T+ R + + IG GS+G+V A+ E E VAIKKV L KR REL
Sbjct: 96 KDKTISYRAEHV--IGTGSFGVVFQAKCLET--EEKVAIKKV-------LQDKRYKNREL 144
Query: 76 KLLRHFRGHKNITCL-YDMDIVFQPDGMFNGLYL--YEELMECDMHQIVKSGQPLTDAHY 132
+++R H N+ L + + D ++ L L E + K Q + +
Sbjct: 145 QIMRML-DHPNVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYI 203
Query: 133 QSFIYQILCGLKYIHSA-DVLHRDLKPGNLLVN-ADCQLKICDFGLARGYSENPVENNQF 190
Q + YQI + Y+H V HRD+KP NLLVN ++KICDFG A+ P E N
Sbjct: 204 QLYTYQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLI--PGEPN-- 259
Query: 191 LTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQV 250
Y+ +R+YRAPE++ YT AID+WS GC++AEL G P+F G+ VDQL I+++
Sbjct: 260 -ISYICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKI 318
Query: 251 LGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLY-PNANPDALNLLEGMLSFDPQLRI 309
LGTP E +K + + D+ + I P+ ++ +P+A++L +L + P LR
Sbjct: 319 LGTPAREEIKNMNPR-YNDF--KFPQIKAQPWHKIFRRQVSPEAMDLASRLLQYSPNLRC 375
Query: 310 TVDDALQHPYLSIWHDP 326
T +A HP+ DP
Sbjct: 376 TALEACAHPFFDDLRDP 392
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 148 bits (374), Expect = 2e-35
Identities = 105/301 (34%), Positives = 154/301 (50%), Gaps = 23/301 (7%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+G GS+GIV A+ E + TVAIKKV R L+ ++LL H C
Sbjct: 80 VGQGSFGIVFQAKCLETGE--TVAIKKV---LQDKRYKNRELQTMRLLDHPNVVSLKHCF 134
Query: 91 YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIH 147
+ + D ++ L Y+ E + H ++ Q + + + + YQI L YIH
Sbjct: 135 FSTT---EKDELYLNLVLEYVPETVYRVSKHYS-RANQRMPIIYVKLYTYQICRALAYIH 190
Query: 148 SA-DVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEI 205
V HRD+KP NLLVN Q+K+CDFG A+ + E N Y+ +R+YRAPE+
Sbjct: 191 GGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKG--EPN---ISYICSRYYRAPEL 245
Query: 206 MLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSK 265
+ YT ID+WS GC+LAELL G+P+F G+ VDQL I++VLGTP E +K +
Sbjct: 246 IFGATEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPN 305
Query: 266 NVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWHD 325
+ Q+ P + P+A++L+ +L + P LR T A+ HP+ D
Sbjct: 306 YTEFKFPQIKAHPW--HKIFHKRTPPEAVDLVSRLLQYSPNLRSTA--AIVHPFFDELRD 361
Query: 326 P 326
P
Sbjct: 362 P 362
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 148 bits (374), Expect = 2e-35
Identities = 108/302 (35%), Positives = 160/302 (52%), Gaps = 23/302 (7%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCL 90
+G GS+GIV A+ E + +VAIKKV + REL+L+R I+
Sbjct: 76 VGTGSFGIVFQAKCLETGE--SVAIKKVLQDR------RYKNRELQLMRPMDHPNVISLK 127
Query: 91 YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYIH 147
+ D +F L Y+ E L H S Q + + + + YQI GL YIH
Sbjct: 128 HCFFSTTSRDELFLNLVMEYVPETLYRVLRHY-TSSNQRMPIFYVKLYTYQIFRGLAYIH 186
Query: 148 SAD-VLHRDLKPGNLLVNA-DCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEI 205
+ V HRD+KP NLLV+ Q+K+CDFG A+ + E N Y+ +R+YRAPE+
Sbjct: 187 TVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKG--EPN---ISYICSRYYRAPEL 241
Query: 206 MLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSK 265
+ YT +ID+WS GC+LAELL G+P+F G++ VDQL I++VLGTP E + R +
Sbjct: 242 IFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEI-RCMNP 300
Query: 266 NVQDYIHQLGYIPKIPF-STLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWH 324
N D+ + I P+ + P+A++L +L + P LR T +A HP+ +
Sbjct: 301 NYTDF--RFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELR 358
Query: 325 DP 326
+P
Sbjct: 359 EP 360
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 148 bits (373), Expect = 2e-35
Identities = 97/293 (33%), Positives = 154/293 (52%), Gaps = 16/293 (5%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
+ ++G G+Y V R E VA+K++ + C ++RE+ LL++ + H NI
Sbjct: 145 LDKLGEGTYATVFKGR--SKLTENLVALKEIRLEHEEGAPCT-AIREVSLLKNLK-HANI 200
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAH-YQSFIYQILCGLKYI 146
L+D+ D L L E ++ D+ Q + L H + F++Q+L GL Y
Sbjct: 201 VTLHDL---IHTD---RSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYC 254
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H +LHRDLKP NLL+N +LK+ DFGLAR S V + E V T WYR P+++
Sbjct: 255 HHRKILHRDLKPQNLLINERGELKLADFGLARAKS---VPTKTYSNE-VVTLWYRPPDVL 310
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKN 266
L Y+ ID+W GCI E+ G+P+F G ++L+ I ++LGTP EET + + +
Sbjct: 311 LGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFS 370
Query: 267 VQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
Y+P+ P P + D ++LL +L ++ + R++ + AL H Y
Sbjct: 371 EFRTYSFPCYLPQ-PLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSY 422
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 148 bits (373), Expect = 2e-35
Identities = 101/310 (32%), Positives = 164/310 (52%), Gaps = 22/310 (7%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
++++ ++++G G+YG V A E VA+KK + + +LRE+ LL+
Sbjct: 2 EKYEKLEKVGEGTYGKVYKAM--EKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 83 GHKNITCLYDMDIVFQPDGMF------NGLYLYEELMECDMHQIVKSGQ------PLTDA 130
I L ++ V Q + LYL E ++ D+ + + S + PL +
Sbjct: 60 QSIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEAS 119
Query: 131 HYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQ 189
Q F++Q+ G+ + HS VLHRDLKP NLL++ D LKI D GL+R ++ P++
Sbjct: 120 LVQRFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTV-PLKA-- 176
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
T + T WYRAPE++L Y+ A+D+WS GCI AE++ + +F G QL I +
Sbjct: 177 -YTHEIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFR 235
Query: 250 VLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRI 309
+LGTP E+ G ++D+ + P+ S P+ +P+ ++LL ML ++P RI
Sbjct: 236 LLGTPTEQQWP--GVMALRDWHVYPKWEPQ-DLSRAVPSLSPEGIDLLTQMLKYNPAERI 292
Query: 310 TVDDALQHPY 319
+ AL HPY
Sbjct: 293 SAKAALDHPY 302
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 147 bits (371), Expect = 4e-35
Identities = 101/305 (33%), Positives = 155/305 (50%), Gaps = 13/305 (4%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++ +++IG G+Y V A+ + VA+KKV + K RE+ +LR H
Sbjct: 114 YEKLEKIGQGTYSNVYKAK--DLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLN-H 170
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
N+ L + + LYL E ME D+ + + G + F+ Q+L GL
Sbjct: 171 PNVIKLQGL----VTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGL 226
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ HS VLHRD+K NLL++ D LKI DFGLA Y + Q +T V T WYR P
Sbjct: 227 EHCHSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDP---KQKQTMTSRVVTLWYRPP 283
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y +D+WS GCI+AELL GKP+ G+ V+QL++I ++ G+P + K+
Sbjct: 284 ELLLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKKYR 343
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW 323
N + Q Y K + + P +++L+E +L+ DP R T AL + +
Sbjct: 344 LPNATLFKPQHPY--KRCVAEAFNGFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTE 401
Query: 324 HDPAD 328
P D
Sbjct: 402 PLPCD 406
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 147 bits (371), Expect = 4e-35
Identities = 98/296 (33%), Positives = 157/296 (52%), Gaps = 13/296 (4%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ +++IG G+Y V AR + + VA+K+V S K RE+ ++R H
Sbjct: 137 FEKLEKIGQGTYSSVYKAR--DLTNNKIVALKRVRFDLSDLESVKFMAREIIVMRRL-DH 193
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK-SGQPLTDAHYQSFIYQILCGL 143
N+ L + + + LYL E M+ D+ + G ++ + ++ Q+L GL
Sbjct: 194 PNVLKLEGLITA----SVSSSLYLVFEYMDHDLVGLASIPGIKFSEPQVKCYMQQLLSGL 249
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+ HS VLHRD+K NLL++++ LKI DFGLA + +N LT V T WYR P
Sbjct: 250 HHCHSRGVLHRDIKGSNLLIDSNGVLKIADFGLATFFDP---QNCVPLTSRVVTLWYRPP 306
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y +D+WS GCIL EL GKPI GK V+QL++I ++ G+P E+ +++
Sbjct: 307 ELLLGACHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPTEDYWRKLK 366
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ L Y ++ + ++ + + L+LLE +LS DP R + AL+ Y
Sbjct: 367 LPPSAAFRPALPYGRRV--AEMFKDLPTNVLSLLEALLSIDPDRRGSAARALESEY 420
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 147 bits (371), Expect = 4e-35
Identities = 103/295 (34%), Positives = 152/295 (50%), Gaps = 19/295 (6%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
K IG+GS+G+V A+ + + VAIKKV R L+ ++ L H K +
Sbjct: 552 KVIGNGSFGVVFQAKLCDTGE--LVAIKKV---LQDRRFKNRELQIMRKLEHCNIVKLLY 606
Query: 89 CLYDMDIVFQPDGMFNGLYL--YEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYI 146
Y + D +F L L E + Q K+ Q + + ++YQ+ L YI
Sbjct: 607 FFYSSGE--KRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYI 664
Query: 147 HSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEI 205
HS + HRD+KP NLL++ + LK+CDFG A+ E N Y+ +R+YRAPE+
Sbjct: 665 HSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHG--EPN---VSYICSRYYRAPEL 719
Query: 206 MLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSK 265
+ YT IDVWS GC+LAELL G+PIF G VDQL +++VLGTP E ++ +
Sbjct: 720 IFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPN 779
Query: 266 NVQDYIHQLGYIPKIPFSTLYPNANP-DALNLLEGMLSFDPQLRITVDDALQHPY 319
+ Q I P+ ++ P +A+NL+ +L + P RIT A HP+
Sbjct: 780 YTEFKFPQ---IKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPF 831
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 147 bits (370), Expect = 5e-35
Identities = 109/316 (34%), Positives = 161/316 (50%), Gaps = 34/316 (10%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKNI 87
K IG+GS+G+V A+ ++ + VAIKKV L KR REL+++R H NI
Sbjct: 60 KVIGNGSFGVVYQAKLCDSGE--LVAIKKV-------LQDKRFKNRELQIMRKL-DHCNI 109
Query: 88 TCL--YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
L + + D ++ L Y+ E + H ++ Q L + + ++YQ+
Sbjct: 110 VRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYS-RAKQTLPVIYVKLYMYQLFRS 168
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
L YIHS + HRD+KP NLL++ D LK+CDFG A+ E N Y+ +R+YR
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN---VSYICSRYYR 223
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++ YT +IDVWS GC+LAELL G+PIF G VDQL I++VLGTP E ++
Sbjct: 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query: 262 IGSKNVQDYIHQLGYIPKIPFST-----------LYPNANPDALNLLEGMLSFDPQLRIT 310
+ + Q+ P S+ P P+A+ L +L + P R+T
Sbjct: 284 MNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLT 343
Query: 311 VDDALQHPYLSIWHDP 326
+A H + DP
Sbjct: 344 PLEACAHSFFDELRDP 359
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 147 bits (370), Expect = 5e-35
Identities = 102/301 (33%), Positives = 159/301 (51%), Gaps = 21/301 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG- 83
+Q + IG G+YG V AR + VA+KKV ++ + +LRE+ LL+
Sbjct: 26 YQELNIIGEGAYGTVYRAR--DVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNAS 83
Query: 84 -HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV----KSGQPLTDAHYQSFIYQ 138
H NI LY++ + DG L ++E + E D+ ++ KSG ++ Q +
Sbjct: 84 NHANIVKLYEVCQFLERDGQLLILLVFEHV-EQDLSDLIDRLPKSG--MSPPTIQRLSRE 140
Query: 139 ILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATR 198
+L G+ ++HS ++HRDLKP NLLV++ LKI DFGLA+ Y + LT V T
Sbjct: 141 LLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYG-----SEMKLTSVVVTL 195
Query: 199 WYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
WYRAPE++L+ Q Y +D+WS CI+ E+ + +F G +QL+RI ++ G P E+
Sbjct: 196 WYRAPEVLLA-QPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQ 254
Query: 259 LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHP 318
+ S ++ + + PK P P+ A +LL MLS+D LR + L+H
Sbjct: 255 WPQTISVALEHFPQR---HPKRP-KDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHD 310
Query: 319 Y 319
Y
Sbjct: 311 Y 311
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 147 bits (370), Expect = 5e-35
Identities = 102/311 (32%), Positives = 157/311 (49%), Gaps = 12/311 (3%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + VA+K++ K SLRE+ L +
Sbjct: 556 EEFQCLNRIEEGTYGVVYRAK--DKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQ 613
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
H NI + ++ + D +F + E ++ M + Q + Q+L
Sbjct: 614 -HPNIVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRA 672
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
+ ++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYRA
Sbjct: 673 VAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYG-SPIKK---YTSLVVTLWYRA 728
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE++L Y+ IDVWS GCI AE L P+F GK +D+LNRI + LGTP E+
Sbjct: 729 PELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGY 788
Query: 263 GS-KNVQDYIHQLGYIPKIPFSTL----YPNANPDALNLLEGMLSFDPQLRITVDDALQH 317
V++ + Q + P S L + L+LL+G+L++DP+ R++ D AL+H
Sbjct: 789 TELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKH 848
Query: 318 PYLSIWHDPAD 328
+ P D
Sbjct: 849 GFFKELPLPID 859
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 146 bits (369), Expect = 6e-35
Identities = 94/300 (31%), Positives = 159/300 (52%), Gaps = 17/300 (5%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R+ + K +G G++G V A+ + D VAIK++ F SLRE+K L+
Sbjct: 44 RYLMTKRLGDGTFGEVMLAKKIDTGDR--VAIKRMKKKFYSWEEAM-SLREVKSLKKLN- 99
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCG 142
H NI L +++ + D LY E M+ ++++++K + ++ ++ IYQ+L G
Sbjct: 100 HPNIIKL--REVIRENDI----LYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQG 153
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
L ++H HRD+KP N++ N +KI DFGLAR P T+YV+TRWYRA
Sbjct: 154 LAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPP-----YTDYVSTRWYRA 208
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PEI+L Y ID+W+ GCI+AEL +P+F G +DQL +I+ +LGTP ++
Sbjct: 209 PEILLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPE- 267
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
G + + + P + + + + L+ M+ ++P+ R + +L++ Y +
Sbjct: 268 GYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYFQV 327
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 146 bits (369), Expect = 6e-35
Identities = 92/302 (30%), Positives = 156/302 (51%), Gaps = 9/302 (2%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+ ++ I G+YG V + T + VA+K+ K +LRE+ +L H
Sbjct: 399 YVILNVIAEGTYGEVFRGKNTRT--DEVVALKRFKMEKEKEGFPITALREINMLLKAGAH 456
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
+NI + ++ + ++ + E ++ + ++ Q ++ + Q+L G++
Sbjct: 457 ENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIE 516
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSE-NPVENNQFLTEYVATRWYRAP 203
++H +LHRDLK NLL++ LKI DFGLAR Y E +E LT V T WYR+P
Sbjct: 517 HMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSP 576
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L + Y+ +D+WS GCI+AE + KP+F+G +Q+++I Q++GTP E+ I
Sbjct: 577 ELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIK 636
Query: 264 SKNVQDYIH----QLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
V + + + G + +I N +LL GML +P R+T +ALQH +
Sbjct: 637 ELKVWNMVEFPPVKPGQLRRIFKGEKL--VNETGFDLLNGMLCLNPANRLTASEALQHDW 694
Query: 320 LS 321
S
Sbjct: 695 FS 696
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 146 bits (369), Expect = 6e-35
Identities = 104/314 (33%), Positives = 163/314 (51%), Gaps = 24/314 (7%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ I +IG G+Y V A+ + VA+KKV + K RE+ +LR H
Sbjct: 118 FEKIDKIGQGTYSNVYKAK--DMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRL-DH 174
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCGL 143
N+ L + M LYL + M+ D+ + S +++ + + Q++ GL
Sbjct: 175 PNVVKLEGL----VTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMRQLISGL 230
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ HS VLHRD+K NLL++ LKI DFGLA + N + + +T V T WYRAP
Sbjct: 231 EHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPN---HKRPMTSRVVTLWYRAP 287
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y ID+WS GCILAELL G+PI G+ V+QL++I ++ G+P E+ K+
Sbjct: 288 ELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKK-- 345
Query: 264 SKNVQDYIHQLGYIPKIPFS----TLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ H Y P+ P+ + + P +L L++ +LS +P+ R T AL+ +
Sbjct: 346 ----GKFTHGAIYKPREPYKRSIRETFKDFPPSSLPLIDALLSIEPEDRQTASAALKSEF 401
Query: 320 LS---IWHDPADEP 330
+ +PAD P
Sbjct: 402 FTSEPYACEPADLP 415
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 146 bits (368), Expect = 8e-35
Identities = 105/328 (32%), Positives = 164/328 (49%), Gaps = 28/328 (8%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R++ + +G GSYG+V R E VA+K+ + K +LRE++LL++ +
Sbjct: 3 RYEKLSRLGEGSYGVVYKCRDRETG--ALVAVKRFVESEDDPAIRKIALREIRLLKNLK- 59
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGL 143
H N+ L + VF+ + ++ + EL +H++ + Q + + YQ L G+
Sbjct: 60 HPNLVSLLE---VFRRKRRLHLVFEFCELTV--LHELERHPQGCPEHLTKQICYQTLLGV 114
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
Y H LHRD+KP N+L+ A Q+K+CDFG AR S P EN T+YVATRWYRAP
Sbjct: 115 AYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLS--PGEN---YTDYVATRWYRAP 169
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E+++ Y +DVW+ GC+ AEL+ G+ ++ G+ VDQL I + LG ++ G
Sbjct: 170 ELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFG 229
Query: 264 SKNVQDYIHQLGYIPKI-PFSTLYP---NANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
I L P + P P NP ++ L+ L DP R + + +H Y
Sbjct: 230 QNEYFKGI-TLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSY 288
Query: 320 LSIWHDPADEPICTEKFDFSFESVNEIE 347
D+ I ++ E VN +E
Sbjct: 289 F-------DDYIAKQR---ELEHVNSLE 306
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 145 bits (367), Expect = 1e-34
Identities = 97/308 (31%), Positives = 162/308 (52%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 418 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 475
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 476 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 530
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T+WYR
Sbjct: 531 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTQWYR 586
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F G +DQ+N++ + LGTP
Sbjct: 587 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP------- 639
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 640 --SEKIWPGYSELPVVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 696
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 697 EDGLKHEY 704
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 80 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 137
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 138 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 192
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 193 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 248
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 249 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 301
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 302 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 358
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 359 EDGLKHEY 366
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 145 bits (367), Expect = 1e-34
Identities = 97/308 (31%), Positives = 162/308 (52%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 421 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 478
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 479 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 533
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T+WYR
Sbjct: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTQWYR 589
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F G +DQ+N++ + LGTP
Sbjct: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP------- 642
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 643 --SEKIWPGYSELPVVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 699
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 700 EDGLKHEY 707
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 145 bits (367), Expect = 1e-34
Identities = 97/308 (31%), Positives = 162/308 (52%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 408 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 465
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 466 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 520
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T+WYR
Sbjct: 521 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTQWYR 576
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F G +DQ+N++ + LGTP
Sbjct: 577 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP------- 629
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 630 --SEKIWPGYSELPVVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 686
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 687 EDGLKHEY 694
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 145 bits (367), Expect = 1e-34
Identities = 97/308 (31%), Positives = 162/308 (52%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 417 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 474
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 475 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 529
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T+WYR
Sbjct: 530 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTQWYR 585
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F G +DQ+N++ + LGTP
Sbjct: 586 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP------- 638
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 639 --SEKIWPGYSELPVVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 695
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 696 EDGLKHEY 703
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 145 bits (367), Expect = 1e-34
Identities = 97/308 (31%), Positives = 162/308 (52%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 38 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 95
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 96 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 150
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T+WYR
Sbjct: 151 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTQWYR 206
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F G +DQ+N++ + LGTP
Sbjct: 207 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP------- 259
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 260 --SEKIWPGYSELPVVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 316
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 317 EDGLKHEY 324
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 412 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 469
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 470 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 524
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 525 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 580
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 581 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 633
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 634 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 690
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 691 EDGLKHEY 698
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 421 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 478
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 479 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 533
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 589
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 642
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 643 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 699
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 700 EDGLKHEY 707
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 102 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 159
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 160 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 214
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 215 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 270
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 271 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 323
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 324 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 380
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 381 EDGLKHEY 388
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 206 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 263
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 264 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 318
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 319 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 374
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 375 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 427
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 428 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 484
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 485 EDGLKHEY 492
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 389 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 446
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 447 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 501
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 502 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 557
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 558 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 610
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 611 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 667
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 668 EDGLKHEY 675
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 378 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 435
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 436 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 490
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 491 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 546
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 547 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 599
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 600 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 656
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 657 EDGLKHEY 664
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 167 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 224
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 225 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 279
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 280 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 335
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 336 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 388
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 389 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 445
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 446 EDGLKHEY 453
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 423 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 480
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 481 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 535
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 536 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 591
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 592 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 644
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 645 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 701
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 702 EDGLKHEY 709
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 162/308 (51%), Gaps = 32/308 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+ FQ + I G+YG+V A+ + + VA+K++ K SLRE+ + +
Sbjct: 436 EEFQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ 493
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILC 141
H NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L
Sbjct: 494 -HPNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 548
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
G+K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T WYR
Sbjct: 549 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTLWYR 604
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++L + Y+ A+D+WS GCI ELL KP+F GK +DQ+N++ + LGTP
Sbjct: 605 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTP------- 657
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITV 311
S+ + +L + K+ FS +P N +L+ L++ P RI+
Sbjct: 658 --SEKIWPGYSELPAVKKMTFSE-HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISA 714
Query: 312 DDALQHPY 319
+D L+H Y
Sbjct: 715 EDGLKHEY 722
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 145 bits (367), Expect = 1e-34
Identities = 98/308 (31%), Positives = 161/308 (51%), Gaps = 20/308 (6%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
++++ ++++G G+YG V A E VA+KK + + +LRE+ LL+
Sbjct: 2 EKYEKLEKVGEGTYGKVYKAM--EKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 83 GHKNITCLYDMDIVFQPD----GMFNGLYLYEELMECDMHQIVKS------GQPLTDAHY 132
+ L ++ V QP + LYL E ++ D+ + + S +PL
Sbjct: 60 TSIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLI 119
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQL-KICDFGLARGYSENPVENNQFL 191
Q ++Q+ G+ + HS VLHRDLKP NLL+ D +L KI D GL R ++ P+++
Sbjct: 120 QKLMFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTV-PLKS---Y 175
Query: 192 TEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVL 251
T + T WYRAPE++L Y+ +D+WS GCI AE++ + +F G QL I ++L
Sbjct: 176 THEIVTLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLL 235
Query: 252 GTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITV 311
GTP E+ G ++D+ + P+ + P+ +P ++LL ML ++P RI+
Sbjct: 236 GTPTEQQWP--GVSTLRDWHVYPKWEPQ-DLTLAVPSLSPQGVDLLTKMLKYNPAERISA 292
Query: 312 DDALQHPY 319
AL HPY
Sbjct: 293 KTALDHPY 300
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 145 bits (367), Expect = 1e-34
Identities = 105/315 (33%), Positives = 160/315 (50%), Gaps = 22/315 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ +++IG G+Y V A TE VA+KKV + K RE+ +LR H
Sbjct: 121 FEKLEKIGQGTYSNVFRAVETETG--RIVALKKVRFDNFEPESVKFMAREILILRRLN-H 177
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCGL 143
NI L + + + L E ME D+ ++ S T + ++ Q+L GL
Sbjct: 178 PNIIKLEGLIT----SKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCYMKQLLSGL 233
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+ HS V+HRD+K NLL++ + LK+ DFGLA +S + + LT V T WYR P
Sbjct: 234 DHCHSRGVMHRDIKGSNLLLSNEGILKVADFGLAN-FSNSSGHKKKPLTSRVVTLWYRPP 292
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y ++D+WS GC+ AELL GKPI +G+ V+QL++I ++ G+PPE+ K+
Sbjct: 293 ELLLGATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDYWKK-- 350
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPD----ALNLLEGMLSFDPQLRITVDDALQHPY 319
H + + P+ + + D +NL+E +LS DP R T AL Y
Sbjct: 351 ----SKLPHAMLFKPQQTYDSCLRETLKDLSETEINLIETLLSIDPHKRGTASSALVSQY 406
Query: 320 LS---IWHDPADEPI 331
+ DP+ PI
Sbjct: 407 FTTKPFACDPSSLPI 421
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 145 bits (367), Expect = 1e-34
Identities = 106/302 (35%), Positives = 156/302 (51%), Gaps = 23/302 (7%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKNITC 89
+G GS+G+V A+ E + VAIKKV L KR REL++++ H N+ C
Sbjct: 88 VGTGSFGMVFQAKCRETGE--VVAIKKV-------LQDKRYKNRELQIMQML-DHPNVVC 137
Query: 90 L-YDMDIVFQPDGMFNGLYL--YEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLKYI 146
L + + + ++ L L E + + Q + + + + YQI GL Y+
Sbjct: 138 LKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLAYL 197
Query: 147 HSA-DVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
H+ + HRD+KP NLLVN QLKICDFG A+ + E N Y+ +R+YRAPE
Sbjct: 198 HNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKG--EPN---ISYICSRYYRAPE 252
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++ YT AID+WS GC++AELL G+P+F G+ VDQL I++VLGTP E +K +
Sbjct: 253 LIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNP 312
Query: 265 KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWH 324
+ Q+ P P+A++LL + P LR T +A HP+
Sbjct: 313 NYTEFKFPQIK--PHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELR 370
Query: 325 DP 326
DP
Sbjct: 371 DP 372
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 145 bits (366), Expect = 1e-34
Identities = 95/307 (30%), Positives = 158/307 (50%), Gaps = 27/307 (8%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
++ + ++G GSYG+V + + VAIKK + K +LRE+++L+ +
Sbjct: 3 KYDRLSKLGEGSYGVVYKCKNRDTGQ--IVAIKKFVETEDDPHIKKIALREIRMLKQLK- 59
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECD---MHQIVKSGQPLTDAHYQSFIYQIL 140
H+N+ L + VF+ + L+L EL CD +H++ K+ + D + IYQ+L
Sbjct: 60 HQNLVGLIE---VFKRN---RKLHLVFEL--CDRTVLHELEKNPHGVNDELIKKIIYQLL 111
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
LK+ HS +HRD+KP N+ + + Q+K+ DFG AR + + T+YVATRWY
Sbjct: 112 EALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFAR-----IINTTEMYTDYVATRWY 166
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
R+PE+++ Y +D+W+ GC+ AELL G+ ++ G+ +DQL I + LG E +
Sbjct: 167 RSPELLVGDVQYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLG---EFLPR 223
Query: 261 RIGSKNVQDYIHQLGYIPK----IPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQ 316
I + L IP+ P + PNA+ L+ L+ P R + + +
Sbjct: 224 HISIFRTNQFFFGLS-IPEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELML 282
Query: 317 HPYLSIW 323
H S W
Sbjct: 283 HGIFSNW 289
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 145 bits (365), Expect = 2e-34
Identities = 97/307 (31%), Positives = 157/307 (50%), Gaps = 14/307 (4%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++ I +IG G+YG V A T D VA+K++ K ++RE+K+L+ R H
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGD--LVALKRIRLEQEKDGFPITTVREVKILQRLR-H 333
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCGL 143
KNI L ++I+ + + +Y+ E M+ D+ ++ + Q T + + QI L
Sbjct: 334 KNIVRL--LEIMVEK----SSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEAL 387
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
Y+H VLHRD+K N+L+N + LK DFGLAR + + N T V T W+R P
Sbjct: 388 AYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSAN---YTNRVITLWFRPP 444
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y A+D+WS GCI+ EL GKP F+G+D + QL I ++GTP + +
Sbjct: 445 ELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVK 504
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW 323
+ + + + T +P A++L + +L+ +P R + + L H Y +
Sbjct: 505 NLPWYELLKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTS- 563
Query: 324 HDPADEP 330
P EP
Sbjct: 564 ESPPPEP 570
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 145 bits (365), Expect = 2e-34
Identities = 106/327 (32%), Positives = 169/327 (51%), Gaps = 35/327 (10%)
Query: 3 EYDAVDRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVF 62
EY + H + NQD +QL++++G G Y V A ++ V I K
Sbjct: 22 EYWDYESHVVEWGNQD-----DYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKK- 75
Query: 63 SKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK 122
K+ RE+K+L + RG NI L DIV P L ++E + D Q+
Sbjct: 76 ------KKIKREIKILENLRGGPNIITL--ADIVKDPVSRTPAL-VFEHVNNTDFKQLY- 125
Query: 123 SGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYS 181
Q LTD + ++Y+IL L Y HS ++HRD+KP N++++ + + L++ D+GLA Y
Sbjct: 126 --QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 183
Query: 182 ENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDY 240
N + VA+R+++ PE+++ YQ Y ++D+WS GC+LA ++ K P F G D
Sbjct: 184 PGQEYNVR-----VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 238
Query: 241 VDQLNRILQVLGTPPEETLKRIGSKNVQ------DYI--HQLGYIPKIPFSTLYPNANPD 292
DQL RI +VLGT E+ I N++ D + H + S +P+
Sbjct: 239 YDQLVRIAKVLGT--EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE 296
Query: 293 ALNLLEGMLSFDPQLRITVDDALQHPY 319
AL+ L+ +L +D Q R+T +A++HPY
Sbjct: 297 ALDFLDKLLRYDHQSRLTAREAMEHPY 323
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 145 bits (365), Expect = 2e-34
Identities = 110/330 (33%), Positives = 167/330 (50%), Gaps = 47/330 (14%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+ ++ +IG G+YG V A ++ VA+K+V K ++RE+K+LR H
Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQ--VALKRVRLENEKEGFPITAIREIKILRQLH-H 367
Query: 85 KNITCLYDMDIVFQPDGMFN------GLYLYEELMECDMHQIVKSGQPLTDAHYQ---SF 135
KNI L MDIV M YL E ++ D+ +++S + L D + S
Sbjct: 368 KNIVRL--MDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKE-LVDFNKDQICSL 424
Query: 136 IYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYV 195
Q+L GL YIH+ LHRD+K N+LVN +LKI D GLAR + + ++ T V
Sbjct: 425 FKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKE----SRLYTNRV 480
Query: 196 ATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP- 254
T WYR PE++L + Y AIDVWS GC+L EL KP+F G + QL I +V G+P
Sbjct: 481 ITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPN 540
Query: 255 ----PEET---------LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGML 301
PE T +KR + +++ F + P +A++LL+ ML
Sbjct: 541 VDNWPELTELVGWNTFRMKRTYQRRIRE-----------EFEHIMPR---EAVDLLDKML 586
Query: 302 SFDPQLRITVDDALQHPYLSIWHDPADEPI 331
+ +P+ RI+ +AL HP++ +P+
Sbjct: 587 TLNPEKRISAKEALNHPWIRSLEHTTVQPL 616
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 144 bits (362), Expect = 4e-34
Identities = 99/296 (33%), Positives = 161/296 (53%), Gaps = 22/296 (7%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVT--NVFSKTLLCKRSLRELKLLRHF 81
R++++++IG G +G V A + E VAIKKV N F L +LRE+K L+
Sbjct: 8 RYKMLEKIGEGVHGCVFKAIDLQRNKE--VAIKKVALKNKFGNIAL--NTLREIKTLQLC 63
Query: 82 RGHKNITCLYDMDIV-FQPDGMFNGLYLYEELMECDMHQIVKSG-QPLTDAHYQSFIYQI 139
+ Y +DI+ PD GL L E ++ +KS PL+ + F +Q+
Sbjct: 64 KSE------YILDIIDIYPD--LTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQM 115
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRW 199
G+ Y+H A ++HRD+KP NLL++ LKI DFGLAR Y P + ++ + V+TRW
Sbjct: 116 FKGIAYLHEAGLMHRDIKPANLLISDTDMLKIADFGLARLYF--PEDESRLYSPQVSTRW 173
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YRAPEI+ Q Y +D+W+ GC++AE+L G P+F G ++QL I++ LG+P
Sbjct: 174 YRAPEILFGSQKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQW 233
Query: 260 KRIGSKNVQDYIH-QLGYIPKIPFSTLYPN-ANPDALNLLEGMLSFDPQLRITVDD 313
+ S + DY + I + L+P+ + +NL+ ++ ++P+ R+ +
Sbjct: 234 PELTS--LPDYSKIRFPNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKNRLKASE 287
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 143 bits (361), Expect = 5e-34
Identities = 96/297 (32%), Positives = 153/297 (51%), Gaps = 34/297 (11%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
++ ++ IG G++GIV A+ E + +A+KKV + ++LRE+K L+
Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETGE--IIALKKVALRRLEDGFPNQALREIKALQEMED 60
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCG 142
++ + + VF G G L E M D+ ++V+ Q PL A +S++ +L G
Sbjct: 61 NQYVV---QLKAVFPHGG---GFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKG 114
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
+ + H+ +++HRDLKP NLL++A QLKI DFGLAR +S + ++ T VATR
Sbjct: 115 VAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSP---DGSRLYTHQVATR---- 167
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
S GCI+ ELL G P+F GK+ ++QL +L++LGTP + +
Sbjct: 168 -----------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPEL 210
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ I +P +P + P+ +P AL+LL L + P RI AL H Y
Sbjct: 211 TELPDYNKISFKEQVP-MPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY 266
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 143 bits (361), Expect = 5e-34
Identities = 96/306 (31%), Positives = 160/306 (51%), Gaps = 32/306 (10%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
FQ + I G+YG+V A+ + + VA+K++ SLRE+ + + H
Sbjct: 418 FQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQ-H 474
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L G+
Sbjct: 475 PNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGV 530
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T+WYRAP
Sbjct: 531 KHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTQWYRAP 586
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L + Y+ A+D+WS GCI ELL KP+F G +DQ+N++ + LGTP
Sbjct: 587 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP--------- 637
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITVDD 313
S+ + +L + K+ FS +P N +L+ L++ P RI+ +D
Sbjct: 638 SEKIWPGYSELPVVKKMTFSE-HPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAED 696
Query: 314 ALQHPY 319
L+H Y
Sbjct: 697 GLKHEY 702
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 143 bits (361), Expect = 5e-34
Identities = 96/306 (31%), Positives = 160/306 (51%), Gaps = 32/306 (10%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
FQ + I G+YG+V A+ + + VA+K++ SLRE+ + + H
Sbjct: 420 FQCLNRIEEGTYGVVYRAK--DKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQ-H 476
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
NI + ++ + D +Y+ +E D+ ++++ QP ++ + Q+L G+
Sbjct: 477 PNIVTVREIVVGSNMDK----IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGV 532
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
K++H +LHRDLK NLL++ LK+ DFGLAR Y +P++ T V T+WYRAP
Sbjct: 533 KHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG-SPLKA---YTPVVVTQWYRAP 588
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L + Y+ A+D+WS GCI ELL KP+F G +DQ+N++ + LGTP
Sbjct: 589 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTP--------- 639
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNAN----------PDALNLLEGMLSFDPQLRITVDD 313
S+ + +L + K+ FS +P N +L+ L++ P RI+ +D
Sbjct: 640 SEKIWPGYSELPVVKKMTFSE-HPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAED 698
Query: 314 ALQHPY 319
L+H Y
Sbjct: 699 GLKHEY 704
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 143 bits (361), Expect = 5e-34
Identities = 104/304 (34%), Positives = 156/304 (51%), Gaps = 17/304 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ ++ IG G+Y V AR E VA+KKV + RE+ +LR H
Sbjct: 146 FEKLEMIGQGTYSSVYRARDLET--NQIVALKKVRFANMDPESVRFMAREIIILRRLN-H 202
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
N+ L + I+ + G +YL E M+ D+ +G T S Q+L GL+
Sbjct: 203 PNVMKLEGL-IISKASG---SMYLIFEYMDHDL-----AGLASTPGIKFSQAQQLLLGLE 253
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
+ HS VLHRD+K NLL++ + LKI DFGL+ Y + Q LT V T WYR PE
Sbjct: 254 HCHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRG---QRKQPLTSRVVTLWYRPPE 310
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++L Y +D+WS GCILAEL GKP+ G+ V+Q+++I ++ G+P EE +R
Sbjct: 311 LLLGSTDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWRRSRL 370
Query: 265 KNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWH 324
++ + Q Y K + + + AL LLE +L+ +P R T ALQ + +
Sbjct: 371 RHATIFKPQHPY--KRCVADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEFFTTKP 428
Query: 325 DPAD 328
P++
Sbjct: 429 FPSE 432
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 143 bits (360), Expect = 7e-34
Identities = 89/300 (29%), Positives = 154/300 (50%), Gaps = 12/300 (4%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
++++ + +G GSYG+V R + VAIKK ++ K ++RE+KLL+ R
Sbjct: 2 EKYENLGLVGEGSYGMVMKCRNKDTG--RIVAIKKFLESDDDKMVKKIAMREIKLLKQLR 59
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
H+N+ L + V + + ++ + + D ++ +G L Q +++QI+ G
Sbjct: 60 -HENLVNLLE---VCKKKKRWYLVFEFVDHTILDDLELFPNG--LDYQVVQKYLFQIING 113
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
+ + HS +++HRD+KP N+LV+ +K+CDFG AR + + T+YVATRWYRA
Sbjct: 114 IGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAP----GEVYTDYVATRWYRA 169
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
PE+++ Y KA+DVW+ GC++ E+ G+P+F G +DQL I+ LG +
Sbjct: 170 PELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELF 229
Query: 263 GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSI 322
V + + P YP + ++L + L DP R + L H + +
Sbjct: 230 NKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQM 289
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 143 bits (360), Expect = 7e-34
Identities = 99/303 (32%), Positives = 152/303 (49%), Gaps = 41/303 (13%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKV---TNVFSKTLLCKRSLRELKL 77
+ +R+ IK +G G + V A+ E+ + VAIKK+ + +K + + ++RE+KL
Sbjct: 1 MSRRYDTIKHLGEGQFANVYLAQDLESGE--CVAIKKIKLGSREEAKDGINRTAIREIKL 58
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP-LTDAHYQSFI 136
L+ H NI L D+ G + L + M+ D+ ++K + L AH ++
Sbjct: 59 LKEIH-HDNIIGLRDVI------GHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNIT 111
Query: 137 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVA 196
Q+L GL+++H +LHRDLKP NLL+N + R V
Sbjct: 112 MQMLLGLEFLHVHWILHRDLKPNNLLMNK----------MGR----------------VV 145
Query: 197 TRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPE 256
TRWYRAPE++ + Y ID+WS GCI+AELL PIF G+ +DQL +I +LG P
Sbjct: 146 TRWYRAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTP 205
Query: 257 ETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQ 316
ET + N Y+ + + + A D L+L+ GM +FDP R+T +LQ
Sbjct: 206 ETWPNMTEMN--SYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQ 263
Query: 317 HPY 319
Y
Sbjct: 264 MEY 266
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 142 bits (359), Expect = 9e-34
Identities = 102/305 (33%), Positives = 147/305 (47%), Gaps = 22/305 (7%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTL-LCKRSLRELKLLRHFR 82
R++ + EIG G+YG V AR + + +V N L ++RE+ LLR
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLE 64
Query: 83 G--HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP--LTDAHYQSFIYQ 138
H N+ L D+ + D ++E + + D+ + P L + + Q
Sbjct: 65 AFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQ-DLRTYLDKAPPPGLPAETIKDLMRQ 123
Query: 139 ILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATR 198
L GL ++H+ ++HRDLKP N+LV + +K+ DFGLAR YS LT V T
Sbjct: 124 FLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMA-----LTPVVVTL 178
Query: 199 WYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEET 258
WYRAPE++L Y +D+WS GCI AE+ KP+F G DQL +I ++G PPE+
Sbjct: 179 WYRAPEVLLQ-STYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDD 237
Query: 259 LKRIGSKNVQDYIHQLGYIP---KIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDAL 315
R D G P P ++ P LL ML+F+P RI+ AL
Sbjct: 238 WPR-------DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRAL 290
Query: 316 QHPYL 320
QH YL
Sbjct: 291 QHSYL 295
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 142 bits (359), Expect = 9e-34
Identities = 106/306 (34%), Positives = 166/306 (53%), Gaps = 27/306 (8%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKNI 87
K IG+GS+G+V A+ + + VAIKKV L KR REL+++R H NI
Sbjct: 40 KVIGNGSFGVVFLAKLSTTNE--MVAIKKV-------LQDKRFKNRELQIMRKLN-HPNI 89
Query: 88 TCL--YDMDIVFQPDGMFNGL---YLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
L + + D ++ L Y+ E + H K Q + + + ++YQ+L
Sbjct: 90 VKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYS-KQRQQIPMIYVKLYMYQLLRS 148
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
L YIHS + HRD+KP NLL++ + LK+CDFG A+ N E N Y+ +R+YR
Sbjct: 149 LAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRN--EPN---VSYICSRYYR 203
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE++ YT +IDVWS G ++AELL G+PIF G VDQL I++VLGTP E ++
Sbjct: 204 APELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQS 263
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANP-DALNLLEGMLSFDPQLRITVDDALQHPYL 320
+ + N +++ + I P++ ++ P +A++L+ ++ + P R T A QH +
Sbjct: 264 M-NPNYKEF--KFPQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSRPTPQAACQHAFF 320
Query: 321 SIWHDP 326
+P
Sbjct: 321 DELRNP 326
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 142 bits (359), Expect = 9e-34
Identities = 108/313 (34%), Positives = 155/313 (49%), Gaps = 29/313 (9%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ + +IG G+Y V AR + + VA+KKV + + RE+++LR H
Sbjct: 134 FEKLDKIGQGTYSNVYRAR--DLDQKKIVALKKVRFDNLEPESVRFMAREIQILRRL-DH 190
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDM-----HQIVKSGQPLTDAHYQSFIYQI 139
NI L + M LYL E ME D+ H +K +++ + ++ Q+
Sbjct: 191 PNIIKLEGL----VTSRMSCSLYLVFEYMEHDLAGLASHPAIK----FSESQVKCYLQQL 242
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRW 199
L GL + HS VLHRD+K NLL++ LKI DFGLA + Q LT V T W
Sbjct: 243 LHGLDHCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPR---QTQPLTSRVVTLW 299
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YR PE++L Y A+D+WS GCILAEL GKPI G+ V+QL++I ++ G+P E+
Sbjct: 300 YRPPELLLGATRYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDYW 359
Query: 260 KRIGSKNVQDYIHQLGYIPKIPFSTL----YPNANPDALNLLEGMLSFDPQLRITVDDAL 315
+ H + P P+ L + AL LLE +LS +P R T AL
Sbjct: 360 VK------SRLPHATIFKPTQPYKRLVGETFKEFPQPALALLETLLSVNPDDRGTATAAL 413
Query: 316 QHPYLSIWHDPAD 328
+ + S P D
Sbjct: 414 KSEFFSTRPLPCD 426
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 142 bits (358), Expect = 1e-33
Identities = 96/309 (31%), Positives = 155/309 (50%), Gaps = 14/309 (4%)
Query: 21 VDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRH 80
V+ + K++G G+Y +V + + +AIK++ K L ++RE+K L+
Sbjct: 3 VNMEYTKEKKVGEGTYAVVYLG--CQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQE 60
Query: 81 FRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL-TDAHYQSFIYQI 139
+ H N+ L D+ + + + L L E + D+ ++K L T A ++++
Sbjct: 61 MQ-HPNVIELIDIFMAY------DNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMT 113
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRW 199
L G+ + H +LHRDLKP NLL + D Q+K+ DFGLAR ++ LT V TRW
Sbjct: 114 LRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAP----HEILTSNVVTRW 169
Query: 200 YRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETL 259
YRAPE++ + YT AID+WS G I AEL+ P G++ VDQ+ + LGTP +
Sbjct: 170 YRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDW 229
Query: 260 KRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ S + + + + A+ AL+ + GML+ +PQ R T L+ Y
Sbjct: 230 PEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDY 289
Query: 320 LSIWHDPAD 328
P+D
Sbjct: 290 FKELPPPSD 298
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 142 bits (358), Expect = 1e-33
Identities = 108/325 (33%), Positives = 164/325 (50%), Gaps = 51/325 (15%)
Query: 30 EIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITC 89
++G G+YG V AR + DE A+K++ C RE+ LLR + H N+
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSAC----REIALLRELK-HPNVIA 80
Query: 90 LYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK---------SGQPLTDAHYQSFIYQIL 140
L + + ++L + E D+ I+K L + +S +YQIL
Sbjct: 81 LQKVFLSHSD----RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQIL 136
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADC----QLKICDFGLARGYSENPVENNQFLTEYVA 196
G+ Y+H+ VLHRDLKP N+LV + ++KI D G AR ++ +P++ L V
Sbjct: 137 DGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFN-SPLKPLADLDPVVV 195
Query: 197 TRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKD---------YVDQLNRI 247
T WYRAPE++L + YTKAID+W+ GCI AELL +PIF + + DQL+RI
Sbjct: 196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRI 255
Query: 248 LQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNAN-----------PDA--L 294
V+G P ++ + I + + +Y + K T Y N++ PD+
Sbjct: 256 FSVMGFPADKDWEDI--RKMPEY----PTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVF 309
Query: 295 NLLEGMLSFDPQLRITVDDALQHPY 319
LL+ +L+ DP RIT + ALQ PY
Sbjct: 310 LLLQKLLTMDPTKRITSEQALQDPY 334
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 142 bits (358), Expect = 1e-33
Identities = 105/320 (32%), Positives = 164/320 (50%), Gaps = 23/320 (7%)
Query: 9 RHTFKVFNQDFTVDKRFQLIK--EIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTL 66
R F F D K+ +K +G GSY V F++ + VA+K++ + +
Sbjct: 174 RKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKG-FSKLTYQR-VALKEI-RLQEEEG 230
Query: 67 LCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV-KSGQ 125
++RE LL+ + H NI L+D+ + L E + D+ Q + K
Sbjct: 231 APFTAIREASLLKELK-HSNIVTLHDIVHTRET------LTFVFEYVNTDLSQYMEKHPG 283
Query: 126 PLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPV 185
L + + F++Q+L GL Y H VLHRD+KP NLL++ +LK+ DFGLAR S V
Sbjct: 284 GLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKS---V 340
Query: 186 ENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKG-KDYVDQL 244
++ + E V T WYR P+++L Y+ ++D+W GCI E++ G P F G +D DQL
Sbjct: 341 PSHTYSHE-VVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQL 399
Query: 245 NRILQVLGTPPEETLKRIGSKNVQDY-IHQLGYIPKIPFSTLYPNANP--DALNLLEGML 301
++I ++LGTP E+T G + Y H+LG+ +P + + G L
Sbjct: 400 DKIFKLLGTPTEDTWP--GVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFL 457
Query: 302 SFDPQLRITVDDALQHPYLS 321
+P+ R+ DDALQHPY +
Sbjct: 458 QLNPEQRLGADDALQHPYFA 477
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 141 bits (356), Expect = 2e-33
Identities = 102/335 (30%), Positives = 159/335 (47%), Gaps = 27/335 (8%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 88
+++G G++G V E + VA+KK+ K L + RE+ +L+ HKNI
Sbjct: 64 EKLGQGTFGEVYKGIHLET--QRQVAMKKIIVSVEKDLFPITAQREITILKRLN-HKNII 120
Query: 89 CLYDMDIVFQPD-------GMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQIL 140
L +M PD + Y+ M D+ ++ + + L ++ + QIL
Sbjct: 121 KLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQIL 180
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE--------NNQFLT 192
GL YIH A +HRD+K N+L++ + LK+ DFGLAR Y P + T
Sbjct: 181 EGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYT 240
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
V TRWYRAPE++L + YT A+D+W GC+ AE KPI +GK +DQ + I ++LG
Sbjct: 241 SVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLG 300
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVD 312
TP EE + + Y P + + L+ L +L+ DP R+T
Sbjct: 301 TPTEEDW-AVARYLPGAELTTTNYKPTLR-ERFGKYLSETGLDFLGQLLALDPYKRLTAM 358
Query: 313 DALQHPYLSIWHDPADEPICTEKFDFSFESVNEIE 347
A HP+ ++P+ +EK E +E +
Sbjct: 359 SAKHHPWFK------EDPLPSEKITLPTEESHEAD 387
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 140 bits (354), Expect = 3e-33
Identities = 99/309 (32%), Positives = 164/309 (53%), Gaps = 32/309 (10%)
Query: 22 DKRFQLIKEIGHGSYGIVCSARFTEAAD-ETTVAIKKVTNVFS---KTLLCKRSLRELKL 77
+ R+ + +++G GS+G V A+ E TVA+KK+ N K L K LRE
Sbjct: 18 EDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLK--LRESLA 75
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK--SGQPLTDAHYQSF 135
LR H CL D+ F + ++L E M+C++ Q+ K G+ T +
Sbjct: 76 LRKISKHP---CLIDLLETFMDP--YRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNI 130
Query: 136 IYQILCGLKYIHSADVLHRDLKPGNLLV--------NADCQLKICDFGLARGYSENPVEN 187
+ QI+ G+++IH +HRD+KP N+LV ++ +K+ DFGLAR P +
Sbjct: 131 LLQIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLAR-----PSVS 185
Query: 188 NQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRI 247
+ LTEYV+TRWYRAPE++L Y ++D+++ GCI+ E+ KP+F G++ DQLNR+
Sbjct: 186 SDPLTEYVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRNETDQLNRV 245
Query: 248 LQVLGTPPEETLKRIGS-KNVQDYIHQLGYI----PKIPFSTLYPNANPDA-LNLLEGML 301
++LG P + L + ++ +LG++ P L P P+ ++ +L
Sbjct: 246 CEILGNPGIDELDTLHYWSQAKELAKRLGFMLPPTKPYPIQKLLPQNCPEGHAKMIPCLL 305
Query: 302 SFDPQLRIT 310
+++P +R T
Sbjct: 306 AWNPDVRPT 314
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 140 bits (354), Expect = 3e-33
Identities = 98/305 (32%), Positives = 154/305 (50%), Gaps = 13/305 (4%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
F+ + +IG G+Y V AR E VA+KKV V + RE+ +LR H
Sbjct: 147 FEKLDKIGQGTYSSVYKARDLETGK--IVAMKKVRFVNMDPESVRFMAREILILRKL-DH 203
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
N+ L + + LYL E ME D+ + + G ++ + ++ Q+ GL
Sbjct: 204 PNVMKLEGL----VTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQLFRGL 259
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
++ H +LHRD+K NLL+N + LKI DFGLA Y + + LT V T WYRAP
Sbjct: 260 EHCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYRG---DGDLQLTSRVVTLWYRAP 316
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++L Y AID+WS GCIL EL GKPI G+ V+Q+++I ++ G+P E+ +R
Sbjct: 317 ELLLGATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDYWRRAT 376
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW 323
+ Y P + + + + AL L+ +L+ +P+ R + L+ + +
Sbjct: 377 LPLATSFKPSHPYKPVL--AETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFFTTE 434
Query: 324 HDPAD 328
PA+
Sbjct: 435 PLPAN 439
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 140 bits (353), Expect = 4e-33
Identities = 105/326 (32%), Positives = 161/326 (49%), Gaps = 53/326 (16%)
Query: 30 EIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITC 89
++G G+YG V A+ + D+ A+K++ C RE+ LLR + H N+
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSAC----REIALLRELK-HPNVIS 80
Query: 90 LYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP---------LTDAHYQSFIYQIL 140
L + + ++L + E D+ I+K + L +S +YQIL
Sbjct: 81 LQKVFLSHAD----RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQIL 136
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADC----QLKICDFGLARGYSENPVENNQFLTEYVA 196
G+ Y+H+ VLHRDLKP N+LV + ++KI D G AR ++ +P++ L V
Sbjct: 137 DGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFN-SPLKPLADLDPVVV 195
Query: 197 TRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKD---------YVDQLNRI 247
T WYRAPE++L + YTKAID+W+ GCI AELL +PIF + + DQL+RI
Sbjct: 196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRI 255
Query: 248 LQVLGTPPEE------------TLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPD--A 293
V+G P ++ TL + +N + Y+ K PD A
Sbjct: 256 FNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEK-------HKVKPDSKA 308
Query: 294 LNLLEGMLSFDPQLRITVDDALQHPY 319
+LL+ +L+ DP RIT + A+Q PY
Sbjct: 309 FHLLQKLLTMDPIKRITSEQAMQDPY 334
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 140 bits (353), Expect = 4e-33
Identities = 91/311 (29%), Positives = 157/311 (50%), Gaps = 23/311 (7%)
Query: 29 KEIGHGSYGIVCSARFTEAADETTVA----IKKVTNVFSKTLLCKRSL-RELKLLRHFRG 83
+ +G G+Y ++ D+ V+ I+ V K K + E+ +R +
Sbjct: 8 RRLGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEISAIREIKS 67
Query: 84 HKNITCLYDMDIV--FQPDGMFNGLYLYEELMECDMHQIVK-SGQPLTDAHYQSFIYQIL 140
K I Y + ++ F D +++ E +E ++ +++ S + + +++I +L
Sbjct: 68 LKRIDSKYVVRLIDTFVYDKC---VHIVLEYVETNLENVIRNSDKIIMPGDIKAWILMVL 124
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
G+ H ++HRD+KP N+L+ ++ +K+ DFGL RG +T TRWY
Sbjct: 125 RGVYECHRLFIIHRDIKPNNILITSEGMVKLADFGLTRGIGNR-------MTPQAVTRWY 177
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
RAPE+++ + Y +D+WS GC+ AEL P+F G + QL+ I + LGTP E
Sbjct: 178 RAPELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTPVEREWP 237
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
G + +++ Y PK + L+ A+ DAL+LLE +L+ +P RI+ DDA++HPY
Sbjct: 238 --GVSTLPEFLDFQQY-PKASLNGLFSAASSDALDLLEKLLTLNPCNRISCDDAIKHPYF 294
Query: 321 SIWHDPADEPI 331
P PI
Sbjct: 295 K--SSPPPTPI 303
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 140 bits (353), Expect = 4e-33
Identities = 107/303 (35%), Positives = 155/303 (50%), Gaps = 25/303 (8%)
Query: 31 IGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR-SLRELKLLRHFRGHKNITC 89
+G GS+G+V A+ E + VAIKKV L KR REL++++ H N
Sbjct: 89 VGTGSFGMVFQAKCRETGE--VVAIKKV-------LQDKRYKNRELQIMQML-DHPNAVA 138
Query: 90 LYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS----GQPLTDAHYQSFIYQILCGLKY 145
L + D L L E + ++++ +S Q + + + + YQI L Y
Sbjct: 139 LKH-SFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRALAY 197
Query: 146 IHSA-DVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
IH++ + HRD+KP NLLVN QLKICDFG A+ + E N Y+ +R+YRAP
Sbjct: 198 IHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKG--EPN---VSYICSRYYRAP 252
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
E++ YT AID+WS GC++AELL G+P+F G+ VDQL I++VLGTP E +K +
Sbjct: 253 ELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMN 312
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLSIW 323
+ Q+ P P+A++LL + P LR T +A HP
Sbjct: 313 PNYTEFKFPQIK--PHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTALEACIHPLFDEL 370
Query: 324 HDP 326
DP
Sbjct: 371 RDP 373
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 140 bits (352), Expect = 6e-33
Identities = 100/294 (34%), Positives = 151/294 (51%), Gaps = 17/294 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
FQ +++IG G+Y V AR E VA+KKV + + RE+ +LR H
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVETGK--MVALKKVKFDNLQPESIRFMAREILILRKLN-H 161
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQP---LTDAHYQSFIYQILC 141
NI L + + +YL E ME D+ + S P T+ + ++ Q+L
Sbjct: 162 PNIMKLEGI----VTSRASSSIYLVFEYMEHDLAGL--SSNPDIRFTEPQIKCYMKQLLW 215
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
GL++ H V+HRD+K N+LVN LK+ DFGLA + P NQ LT V T WYR
Sbjct: 216 GLEHCHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVT--PSNKNQ-LTSRVVTLWYR 272
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE+++ Y ++D+WS GC+ AE+L GKPI KG+ ++QL++I ++ G+P + KR
Sbjct: 273 APELLMGSTSYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSPQDSFWKR 332
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDAL 315
+ + Q Y + + + + LLE +LS +P R T AL
Sbjct: 333 TKLPHATSFKPQHTY--EATLRERCKDLSATGVYLLETLLSMEPDKRGTASSAL 384
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 139 bits (351), Expect = 7e-33
Identities = 106/324 (32%), Positives = 158/324 (48%), Gaps = 28/324 (8%)
Query: 13 KVFNQDFTVDKR---FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCK 69
KV T +K+ ++ + +G GS+G+V A+ +A+K+V L K
Sbjct: 10 KVVTDGTTGEKKTISYEPCRVLGSGSFGVVIQAKLVGTPG--FIAVKRV-------LQDK 60
Query: 70 R-SLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELME----CDMHQIVKSG 124
R REL+++R H NI L P L L E M DM +
Sbjct: 61 RYKNRELQIMRAI-SHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRR 119
Query: 125 QPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSEN 183
+ + + + + +Q+ L Y+HS V HRD+KP NLLV+ LK+CDFG A+
Sbjct: 120 KSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLV-- 177
Query: 184 PVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQ 243
P E N Y+ +R+YRAPE++ YT IDVWS C++AEL G+P+F G V+Q
Sbjct: 178 PSEPN---VSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQ 234
Query: 244 LNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYP-NANPDALNLLEGMLS 302
L I++VLGTP + I N H L + ++ P N +A++LL ML+
Sbjct: 235 LVEIIRVLGTP---SYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLT 291
Query: 303 FDPQLRITVDDALQHPYLSIWHDP 326
+ P RI+ + L HP+ DP
Sbjct: 292 YVPSKRISAIEVLTHPFFDELRDP 315
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 139 bits (350), Expect = 1e-32
Identities = 96/297 (32%), Positives = 150/297 (50%), Gaps = 16/297 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++ + ++G G+Y V R VA+K++ + C ++RE+ LLR+ R H
Sbjct: 361 YEKLDKLGEGTYATVFRGR--SILTNKFVALKEIRLEQEEGAPCT-AIREVSLLRNLR-H 416
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
N+ L+D + D + L L E ++ D+ Q + S + + + F+YQ+L GL
Sbjct: 417 ANVVTLHD---IIHTDRL---LTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGL 470
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
Y H VLHRDLKP NLL+ A +LK+ DFGLAR S V + E V T WYR P
Sbjct: 471 AYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKS---VPTKTYSNE-VVTLWYRPP 526
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
+++L Y+ ID+W GCIL E++ G+ +F G +QL I + LG+P + I
Sbjct: 527 DVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTIC 586
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
K Y P P P + LL L ++ + R++ +A++HP+L
Sbjct: 587 EKPTFYPYANRHYNPD-PLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL 642
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 139 bits (350), Expect = 1e-32
Identities = 96/297 (32%), Positives = 150/297 (50%), Gaps = 16/297 (5%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++ + ++G G+Y V R VA+K++ + C ++RE+ LLR+ R H
Sbjct: 238 YEKLDKLGEGTYATVFRGR--SILTNKFVALKEIRLEQEEGAPCT-AIREVSLLRNLR-H 293
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQILCGL 143
N+ L+D + D + L L E ++ D+ Q + S + + + F+YQ+L GL
Sbjct: 294 ANVVTLHD---IIHTDRL---LTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGL 347
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
Y H VLHRDLKP NLL+ A +LK+ DFGLAR S V + E V T WYR P
Sbjct: 348 AYCHQRRVLHRDLKPQNLLITAKGELKLADFGLARAKS---VPTKTYSNE-VVTLWYRPP 403
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIG 263
+++L Y+ ID+W GCIL E++ G+ +F G +QL I + LG+P + I
Sbjct: 404 DVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTIC 463
Query: 264 SKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
K Y P P P + LL L ++ + R++ +A++HP+L
Sbjct: 464 EKPTFYPYANRHYNPD-PLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL 519
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 139 bits (349), Expect = 1e-32
Identities = 111/380 (29%), Positives = 174/380 (45%), Gaps = 32/380 (8%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
+++ + +IG G++G V AR + + VA+KKV K +LRE+K+L+ +
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQK--VALKKVLMENEKEGFPITALREIKILQLLK- 74
Query: 84 HKNITCLYDM-DIVFQPDGMFNG-LYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQIL 140
H+N+ L ++ P G +YL + E D+ ++ + T + + + +L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GL YIH +LHRD+K N+L+ D LK+ DFGLAR +S T V T WY
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWY 194
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
R PE++L + Y ID+W GCI+AE+ PI +G QL I Q+ G+ E
Sbjct: 195 RPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWP 254
Query: 261 RIGSKNVQDYIHQL-GYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPY 319
+ + + + + + G K+ +P AL+L++ +L DP RI DDAL H +
Sbjct: 255 NVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDF 314
Query: 320 LSIWHDPADEPICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQYVRLPLLHEQQQQQGKT 379
W DP LK M+ +T +Y+ P Q Q T
Sbjct: 315 --FWSDPMP------------------SDLKGMLSTHLTSMFEYLAPPRRKGSQITQQST 354
Query: 380 DGGFDDQIREDQRTFQAQLE 399
+Q R T Q + E
Sbjct: 355 -----NQSRNPATTNQTEFE 369
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 137 bits (346), Expect = 3e-32
Identities = 92/301 (30%), Positives = 152/301 (49%), Gaps = 30/301 (9%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKV-------TNVFSKTLLCKRSLREL 75
+ ++ + I GS+G V R D A+K++ TN FS + RE+
Sbjct: 24 ENYEKVCRISSGSFGNVYRVR--RKTDNRVFALKRMNPSMCYDTNGFSILYI-----REV 76
Query: 76 KLLRHFRGHKNITCLYDMDIVFQPDGM-FNGLYLYEELMECDMHQIVKSGQPLTDAHYQS 134
+L+H R H+NI M+I +G N ++ E + D+ ++ S + +
Sbjct: 77 MILKHIR-HRNI-----MEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVGKIGMKAARF 130
Query: 135 FIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEY 194
Q+L GLK++H A ++HRDLKP N+L+ D L+I DFGLAR +T
Sbjct: 131 LTCQMLKGLKFLHGAGIVHRDLKPSNILLMRDGGLRIADFGLARAIESQ-------MTNL 183
Query: 195 VATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP 254
V T WYR EI+L + Y ++ID+WS GC++ E+L G+PI G+ +DQL+RI ++LG P
Sbjct: 184 VVTLWYRPIEILLGSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYP 243
Query: 255 PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDA 314
+ + + + ++ + + F + +A + + +LSFDP+ R T
Sbjct: 244 TDADFEGLDLPHFKNIRRPSTF--EASFEGDFECYGEEAASFVRNLLSFDPRKRCTASQG 301
Query: 315 L 315
L
Sbjct: 302 L 302
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 137 bits (345), Expect = 4e-32
Identities = 105/327 (32%), Positives = 168/327 (51%), Gaps = 35/327 (10%)
Query: 3 EYDAVDRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVF 62
EY + H NQD +QL++++G G Y V A + V I K
Sbjct: 23 EYWDYEAHVPSWGNQD-----DYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKK- 76
Query: 63 SKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK 122
K+ RE+K+L + RG NI L +D V P L ++E + D Q+
Sbjct: 77 ------KKIKREVKILENLRGGTNIIKL--IDTVKDPVSKTPAL-VFEYINNTDFKQLY- 126
Query: 123 SGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVN-ADCQLKICDFGLARGYS 181
Q LTD + ++Y++L L Y HS ++HRD+KP N++++ +L++ D+GLA Y
Sbjct: 127 --QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYH 184
Query: 182 ENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELL-GGKPIFKGKDY 240
N + VA+R+++ PE+++ YQ Y ++D+WS GC+LA ++ +P F G+D
Sbjct: 185 PAQEYNVR-----VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDN 239
Query: 241 VDQLNRILQVLGTPPEET---LKRIGSKNVQDYIHQLGYIPKIPFSTLYPNAN-----PD 292
DQL RI +VLGT EE LK+ + LG + + + N P+
Sbjct: 240 YDQLVRIAKVLGT--EELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPE 297
Query: 293 ALNLLEGMLSFDPQLRITVDDALQHPY 319
AL+LL+ +L +D Q R+T +A++HPY
Sbjct: 298 ALDLLDKLLRYDHQQRLTAKEAMEHPY 324
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 137 bits (345), Expect = 4e-32
Identities = 86/234 (36%), Positives = 123/234 (51%), Gaps = 31/234 (13%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R++ I+ G G++G+V AR T + + V NV +L RE+ LR+
Sbjct: 7 RYETIQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNVSKVSLA-----REISCLRNLH- 60
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGL 143
H+NI L D D+ IV P Y + QIL G+
Sbjct: 61 HRNILKLLDC------------------FPSADLMSIVTEEVP-----YTWYYTQILSGI 97
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
Y+HS +++HRD+KP N+LV + +KI DFG A Y P + NQ VATRWYRAP
Sbjct: 98 AYLHSKEIMHRDIKPENILVTSRNVVKIADFGQACFYM--PKDPNQEYDVNVATRWYRAP 155
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEE 257
E++ + Y +D+W+ GCILAEL+ GKPIF G+ ++Q++ I VLGTP E+
Sbjct: 156 ELLFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNED 209
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 137 bits (345), Expect = 4e-32
Identities = 87/318 (27%), Positives = 157/318 (49%), Gaps = 20/318 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++ + + G++G+V + + + VA+K++ K +LRE+ +L H
Sbjct: 356 YECVNRVDEGTFGVVYRGK--DKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNH 413
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
NI + ++ + D ++ + E M+ + + + + + ++ + Q+L G++
Sbjct: 414 PNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIE 473
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
++H +LHRDLK NLL++ LKI DFGLAR Y + P++ T V T WYR+PE
Sbjct: 474 HMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGD-PLKK---FTSIVVTLWYRSPE 529
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++L + Y+ +D+WS GCI+AE + KP+F G+ ++Q+ +I +GTP E +
Sbjct: 530 LLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTE 589
Query: 265 KNVQDYIHQLGYIPKIPFSTLYPN------ANPDALNLLEGMLSFDPQLRITVDDALQHP 318
+ + K P++ L N LL G+L+ DP+ R + AL H
Sbjct: 590 LDGWKAL----TFEKYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHE 645
Query: 319 YLSIWHDPADEPICTEKF 336
W P+ E+F
Sbjct: 646 ----WFTEEPYPVPPEEF 659
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 136 bits (343), Expect = 6e-32
Identities = 98/288 (34%), Positives = 155/288 (53%), Gaps = 32/288 (11%)
Query: 65 TLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVK-- 122
T + + + RE+ L R +K++T L ++ + + +++ E E D+ QI+
Sbjct: 198 TGISQSACREMALCRELH-NKHLTTLVEIFLERKC------VHMVYEYAEHDLLQIIHFH 250
Query: 123 ---SGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARG 179
+ + +S ++Q+L G+ Y+H VLHRDLKP N++V D +KI D GLAR
Sbjct: 251 SHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARK 310
Query: 180 YSENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKD 239
+ N ++ + V T WYRAPE++L + YT A+D+WS GCI AEL+G +PIFKG++
Sbjct: 311 F-HNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEE 369
Query: 240 -----------YVDQLNRILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKI--PFSTLY 286
V+QL RIL+VLGTP ++ + D Q+ PK +T Y
Sbjct: 370 AKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYD---QITKFPKYRDNLATWY 426
Query: 287 PNA---NPDALNLLEGMLSFDPQLRITVDDALQHPYLSIWHDPADEPI 331
+A + AL+LL +L++DP RI +AL+H Y + P E +
Sbjct: 427 HSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENV 474
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 135 bits (340), Expect = 1e-31
Identities = 96/310 (30%), Positives = 156/310 (49%), Gaps = 24/310 (7%)
Query: 16 NQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLREL 75
N T+D + + +GHGS+G+V + E + VAIKKV R L +
Sbjct: 155 NHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQK--VAIKKV---LQDRRYKNRELETM 209
Query: 76 KLLRHFRGHKNITCLYDMDIVFQPDGMFNGL---YLYEELMECDMHQI-VKSGQPLTDAH 131
K+L H Y+ D + D ++ L Y+ + L + H + +K P +
Sbjct: 210 KMLCHPNTVGLQYYFYEKD---EEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIK 266
Query: 132 YQSFIYQILCGLKYIHSAD-VLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQ 189
+ + YQ+ L Y+H+ + HRD+KP NLLV+ KICDFG A+ ++ +Q
Sbjct: 267 F--YAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKC-----LKPDQ 319
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQ 249
Y+ +R+YRAPE+M Y+ +DVWS C++AELL GKP+F G+ +DQL I++
Sbjct: 320 PNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIK 379
Query: 250 VLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRI 309
++G P ++ + + + N +D H I I + ++ +PD L+LL L + P R+
Sbjct: 380 IMGIPTKDEISGM-NPNYED--HVFPNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERL 436
Query: 310 TVDDALQHPY 319
L Y
Sbjct: 437 VPLQCLLSSY 446
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 135 bits (340), Expect = 1e-31
Identities = 100/328 (30%), Positives = 166/328 (50%), Gaps = 35/328 (10%)
Query: 2 NEYDAVDRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNV 61
+EY + + NQD +QL++++G G Y V A ++ V I K
Sbjct: 19 DEYWDYENYVVDWGNQD-----DYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKK 73
Query: 62 FSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV 121
K+ RE+K+L + RG NI L + +V P L ++E + D Q+
Sbjct: 74 -------KKIKREIKILENLRGGTNIITL--LAVVKDPVSRTPAL-IFEHVNNTDFKQLY 123
Query: 122 KSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGY 180
Q LTD + +++++L L Y HS ++HRD+KP N++++ + + L++ D+GLA Y
Sbjct: 124 ---QTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFY 180
Query: 181 SENPVENNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKD 239
N + VA+R+++ PE+++ YQ Y ++D+WS GC+LA ++ K P F G D
Sbjct: 181 HPGQEYNVR-----VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHD 235
Query: 240 YVDQLNRILQVLGTPPEETLKRIGSKNV------QDYI--HQLGYIPKIPFSTLYPNANP 291
DQL RI +VLGT EE + N+ D + H + S +P
Sbjct: 236 NYDQLVRIAKVLGT--EELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSP 293
Query: 292 DALNLLEGMLSFDPQLRITVDDALQHPY 319
+AL+ L+ +L +D R+T +A+ HPY
Sbjct: 294 EALDFLDKLLRYDHVDRLTAREAMAHPY 321
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 134 bits (338), Expect = 2e-31
Identities = 96/313 (30%), Positives = 159/313 (50%), Gaps = 46/313 (14%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+QL++++G G Y V F + DE KV K + K+ RE+K+L + RG
Sbjct: 38 YQLVRKLGRGKYSEVFEG-FKMSTDE------KVVVKILKPVKKKKIKREIKILENLRGG 90
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
NI L +D+V P L ++E + D Q+ Q L+D + ++Y++L L
Sbjct: 91 TNIITL--LDVVKDPISRTPAL-IFEHVNNSDFKQLY---QTLSDYDIRYYLYELLKALD 144
Query: 145 YIHSADVLHRDLKPGNLLVNADC-QLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+ HS ++HRD+KP N++++A+ +L++ D+GLA Y N + VA+R+++ P
Sbjct: 145 FCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVR-----VASRYFKGP 199
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDYVDQLNRILQVLGTPP------- 255
E+++ YQ Y ++D+WS GC+LA ++ K P F G D DQL RI +VLGT
Sbjct: 200 ELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIAR 259
Query: 256 ---------EETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQ 306
+ L R K + +IH + P+AL+ L+ +L +D
Sbjct: 260 YHIDLDPRFNDILGRHSRKRWERFIH----------AENQHLVTPEALDFLDKLLRYDHA 309
Query: 307 LRITVDDALQHPY 319
R+T +A+ H Y
Sbjct: 310 ERLTAQEAMGHEY 322
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 134 bits (337), Expect = 3e-31
Identities = 98/308 (31%), Positives = 157/308 (50%), Gaps = 33/308 (10%)
Query: 19 FTVDK-RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKL 77
FT K ++ I+ IG G++G V AR A A+KKV+ K L ++RE+++
Sbjct: 15 FTATKMEYEKIRIIGEGTFGQVILARKGRAR----YALKKVSK--EKEGLSVTTIREVQV 68
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIY 137
LR GH +I L +++V +P G +Y+ D+++ ++S + +T + + Y
Sbjct: 69 LRAM-GHPSIVRL--IEVVVEPGG---DIYMVFPYFPYDLNRFIRSNK-MTCSEIKHIFY 121
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVAT 197
QI G+ YIHS ++HRDLK N+L++ I DFG+AR ++ T + T
Sbjct: 122 QIAQGVCYIHSKGIMHRDLKSANILLDQKLNASIADFGMARYTTKTGA-----YTPGMVT 176
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEE 257
WYRAPEI+L YT A+D+WS GCIL E+ G IF+G + QL ++ G+ E
Sbjct: 177 LWYRAPEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGSINEN 236
Query: 258 TLKRI----GSKNVQDYIHQLGYIPKIP--FSTLYPNANPDALNLLEGMLSFDPQLRITV 311
+ + G +N + +P+ P + + A+ L+ ML DP RITV
Sbjct: 237 SYPGVQDLPGFRNFR--------LPQSPRRIEGIIRKHDASAVELVSKMLCLDPSKRITV 288
Query: 312 DDALQHPY 319
+ + Y
Sbjct: 289 EQVVGSKY 296
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 132 bits (333), Expect = 9e-31
Identities = 90/323 (27%), Positives = 158/323 (48%), Gaps = 49/323 (15%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
I ++G G+YG V A+ T E VA+KK+ + S+RE+KLL+ F H N+
Sbjct: 186 IMQVGEGTYGKVYKAKNTNT--EKLVALKKLRLQGEREGFPITSIREIKLLQSF-DHPNV 242
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQ-PLTDAHYQSFIYQILCGLKYI 146
+ + ++ + Q +Y+ E + D+ ++ + + ++ + + Q+L G++Y+
Sbjct: 243 STIKEIMVESQKT-----VYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYL 297
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H +LHRD+K N+L++ LKI DFGLAR + N+ V T WYR PE++
Sbjct: 298 HDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNR-----VITLWYRPPELL 352
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP------------ 254
L Y +D+W CGC+L EL IF+G + ++Q+ I +++GTP
Sbjct: 353 LGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMP 412
Query: 255 ------PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLR 308
P++T K + + + + F ++ P++ L L +L +D R
Sbjct: 413 WFFMIMPQQTTKYVNNFSEK-------------FKSVLPSSK--CLQLAINLLCYDQTKR 457
Query: 309 ITVDDALQHPYLSIWHDPADEPI 331
+ +ALQ Y +P EP+
Sbjct: 458 FSATEALQSDYFK--EEPKPEPL 478
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 132 bits (333), Expect = 9e-31
Identities = 93/311 (29%), Positives = 153/311 (48%), Gaps = 16/311 (5%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
+++ + +IG G++G V AR + ++ VA+KKV K +LRE+++L+ +
Sbjct: 49 KYEKVAKIGQGTFGEVFKAR-EKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLK- 106
Query: 84 HKNITCLYDM--DIVFQPDGMFNGLYLYEELMECDMHQIVKS-GQPLTDAHYQSFIYQIL 140
H+N+ L ++ +G + YL + E D+ ++ + + + + Q+L
Sbjct: 107 HENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLL 166
Query: 141 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWY 200
GL YIHS +LHRD+K N+L+ LK+ DFGLAR +S E+ T V T WY
Sbjct: 167 NGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVTLWY 226
Query: 201 RAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLK 260
R PE++L + Y +D+W GCI+AE+ PI +G QL I Q+ G+ +
Sbjct: 227 RPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWP 286
Query: 261 RIGSKNVQDYIHQLGYIPKIPFSTLYPNANP-----DALNLLEGMLSFDPQLRITVDDAL 315
+ + I +PK + P +LL+ +L+ DP+ RI D AL
Sbjct: 287 GVEELELYKSIE----LPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTAL 342
Query: 316 QHPYLSIWHDP 326
H + W DP
Sbjct: 343 NHDF--FWTDP 351
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 132 bits (332), Expect = 1e-30
Identities = 90/260 (34%), Positives = 130/260 (49%), Gaps = 15/260 (5%)
Query: 73 RELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELME----CDMHQIVKSGQPLT 128
REL+++R H NI L P L L E M DM + + +
Sbjct: 34 RELQIMRAI-SHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIP 92
Query: 129 DAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVEN 187
+ + + +Q+ L Y+HS V HRD+KP NLLV+ LK+CDFG A+ P E
Sbjct: 93 NLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLV--PSEP 150
Query: 188 NQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRI 247
N Y+ +R+YRAPE++ YT IDVWS C++AEL G+P+F G V+QL I
Sbjct: 151 N---VSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEI 207
Query: 248 LQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYP-NANPDALNLLEGMLSFDPQ 306
++VLGTP + I N H L + ++ P N +A++LL ML++ P
Sbjct: 208 IRVLGTP---SYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPS 264
Query: 307 LRITVDDALQHPYLSIWHDP 326
RI+ + L HP+ DP
Sbjct: 265 KRISAIEVLTHPFFDELRDP 284
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 131 bits (329), Expect = 3e-30
Identities = 100/316 (31%), Positives = 157/316 (49%), Gaps = 36/316 (11%)
Query: 24 RFQLIKE---IGHGSYGIVCSARFTEAADETT--VAIKKVTNVFSKTLLCKRSLRELKLL 78
R L+KE IG G++G V A T+ AIKKV + REL++L
Sbjct: 31 RRMLVKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVP------AHTEYKSRELQIL 84
Query: 79 RHFRGHKNITCLYDMDIVFQPDGMFNGLYLY------EELMECDMHQIVKSGQPLTDAHY 132
R H NI L P N +Y + E ++ ++++ V + + H
Sbjct: 85 R-IADHPNIVKLQYFFTHLSPQD--NKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHI 141
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFL 191
+ + YQI G+ Y+H V HRD+KP N+LV+ + LKICDFG A+ +E+NQ
Sbjct: 142 RLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAK-----KLEHNQPS 196
Query: 192 TEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVL 251
Y+ +R+YRAPE+++ YT ID+W GC++ E+L GK IF+G++ + QL I ++L
Sbjct: 197 ISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLL 256
Query: 252 GTPPEETLKRIGSKNVQDYIHQLGYIPKIP------FSTLYPNANPDALNLLEGMLSFDP 305
G P KR + Y L P F + ++ PD ++LL +L ++P
Sbjct: 257 GPPD----KRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEP 312
Query: 306 QLRITVDDALQHPYLS 321
Q R++ L H + +
Sbjct: 313 QQRLSPRRILAHQFFN 328
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 131 bits (329), Expect = 3e-30
Identities = 100/313 (31%), Positives = 154/313 (48%), Gaps = 43/313 (13%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++ ++++G GSY V + + VA+K V + + ++RE LL+ + H
Sbjct: 117 YEKLEKLGEGSYATVYKGK--SKVNGKLVALK-VIRLQEEEGTPFTAIREASLLKGLK-H 172
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIV-KSGQPLTDAHYQSFIYQILCGL 143
NI L+D+ + L L E + D+ Q + K L + + F++Q+L GL
Sbjct: 173 ANIVLLHDIIHTKET------LTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGL 226
Query: 144 KYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
YIH +LHRDLKP NLL++ +LK+ DFGLAR S V ++ + E V T WYR P
Sbjct: 227 SYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKS---VPSHTYSNE-VVTLWYRPP 282
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKG-KDYVDQLNRILQVLGTPPEETLKRI 262
+++L Y+ +D+W GCI E++ G F G KD DQL RI VLGTP E+T +
Sbjct: 283 DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV 342
Query: 263 --------------GSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLR 308
SKN++ ++L Y+ A +L +L P+ R
Sbjct: 343 HSLPHFKPERFTLYSSKNLRQAWNKLSYV-------------NHAEDLASKLLQCSPKNR 389
Query: 309 ITVDDALQHPYLS 321
++ AL H Y S
Sbjct: 390 LSAQAALSHEYFS 402
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 131 bits (329), Expect = 3e-30
Identities = 91/309 (29%), Positives = 154/309 (49%), Gaps = 31/309 (10%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHF- 81
K FQ+ + +G G+YG V R D A+K++ + + LRE+ +++H
Sbjct: 36 KDFQIHQALGKGAYGNVYRVRSLH--DGKDYALKQIMISSKNEGIPQSVLREITVMKHLA 93
Query: 82 -RGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS---GQPLTDAHYQSFIY 137
+ H NI L + P + + E + D+H +++ G P A + +
Sbjct: 94 RKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTA-- 151
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVAT 197
QI+ L ++H+ ++HRDLKP N+L+N D +K+ DFGL++ YS N T V T
Sbjct: 152 QIVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYS-----NTTAFTTLVVT 206
Query: 198 RWYRAPEIML-SYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTP-- 254
WYR+PE++L SY Y +D+W+ GCI++E+ +P+F G++ +QL I + +GTP
Sbjct: 207 LWYRSPEVLLQSY--YNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVG 264
Query: 255 ---PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITV 311
P E++ I + Y L P + A+ ++ L +D R++
Sbjct: 265 KDWPSESV--IARDSFPQY-------RPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSA 315
Query: 312 DDALQHPYL 320
AL HP+L
Sbjct: 316 RGALSHPFL 324
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 131 bits (329), Expect = 3e-30
Identities = 116/432 (26%), Positives = 192/432 (43%), Gaps = 59/432 (13%)
Query: 25 FQLIKEIGHGSYGIVCSA---RFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHF 81
F+ KEIG G+YG+V A + A+K + C RE+ L R
Sbjct: 26 FENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMIEGQGFSMSAC----REIALFREL 81
Query: 82 RGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHY--------- 132
R H N+ CL + + + ++L + E D+ ++K +
Sbjct: 82 R-HPNLICLQRVFLTNEKK-----VWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMV 135
Query: 133 QSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADC------QLKICDFGLARGYSENPVE 186
++ ++QIL G+ Y+HS VLHRDLKP N+L+ D ++KI D G +R Y+ NP++
Sbjct: 136 KNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYA-NPLK 194
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKD------- 239
L V T WYRAPE++L + YTKAIDVW+ GCI AELL +P+F K+
Sbjct: 195 PMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQN 254
Query: 240 --YVDQLNRILQVLGTP-----PEETLKRIGSKNVQDYIHQLGYIPKIP------FSTLY 286
+ DQ+ RI +LG P P+ + + D ++ I P F
Sbjct: 255 PYHYDQVKRIFHLLGYPSDADWPDMKKMPDHQRLLSDARNEGTPIQTFPNSLHRYFDKWK 314
Query: 287 PNANPDALNLLEGMLSFDPQLRITVDDALQHPYL-SIWHDPADEPICTEKFDFSFESVNE 345
N+ LL +L+ DP R++ ++A+ Y + P + K+ + +
Sbjct: 315 INSQSSPYRLLVKLLTVDPTKRVSCEEAMNDIYFRKMERPPRETDDVFNKYPIPYAKKEQ 374
Query: 346 IEQLKQMVIDEVTDFRQYVRLPLLHEQQQQQGKTDGGFDDQIREDQRTFQAQLEEQVNNG 405
++ +++ + + + L + +Q QQQ Q ++ Q Q Q+ +Q G
Sbjct: 375 QMTVRASIVEYTANVPK-ILLQVAPDQAQQQ--------HQQQQVQMQQQPQMGQQQMMG 425
Query: 406 RTASNVPSFDEP 417
+ P +P
Sbjct: 426 QPQMVQPQMGQP 437
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 130 bits (328), Expect = 3e-30
Identities = 101/317 (31%), Positives = 159/317 (49%), Gaps = 37/317 (11%)
Query: 21 VDKRFQLIKEIGHGSYGIV--CSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLL 78
V+ ++ I ++G GSY V C ++ D + VA+K++ F + L ++RE LL
Sbjct: 104 VNDLYKRIDKLGEGSYATVYKCESKL----DGSIVALKEIKLQFQEGLPFT-AIREASLL 158
Query: 79 RHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSG-QPLTDAHYQSFIY 137
R+ R H NI L+D I +Q + L E M+ D+ + ++ L + ++
Sbjct: 159 RNLR-HANIVSLHD--IFYQ----HHQLTFVFEYMKMDLSKYLEQNVYGLDSIDIKLLLF 211
Query: 138 QILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVAT 197
Q+L GL + H +LHRDLKP NLL++ D LK+ DFGLAR S V + + E V T
Sbjct: 212 QLLRGLDFCHRKKILHRDLKPQNLLLDEDGVLKLADFGLARAKS---VPSRTYSHE-VVT 267
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKG-KD-----YVDQLNRILQVL 251
WYR P++++ Y+ ++D+W GCI AE+ G +F G KD DQL+ I +
Sbjct: 268 LWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLDMIFSIR 327
Query: 252 GTPPEETLKRIGSKNVQDY-------IHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFD 304
GTP E+ + K + Y +L +I P T + L +L L
Sbjct: 328 GTPDEKKWPEV--KTLPGYTPELFPRYRELSFIAVNPMFTKILKTGQELLGML---LQLR 382
Query: 305 PQLRITVDDALQHPYLS 321
P+ R++ A+ HPY +
Sbjct: 383 PESRVSAASAMLHPYFA 399
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 130 bits (326), Expect = 6e-30
Identities = 87/301 (28%), Positives = 148/301 (48%), Gaps = 21/301 (6%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
++ + ++G GSYG V + + K+ + + K ++RE+K L+ F H
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAI---KIFYERPEQSVNKIAMREIKFLKQFH-H 59
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
+N+ L + VF+ + ++ + + D Q G L + +++QIL +
Sbjct: 60 ENLVNLIE---VFRQKKKIHLVFEFIDHTVLDELQHYCHG--LESKRLRKYLFQILRAID 114
Query: 145 YIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPE 204
Y+HS +++HRD+KP N+LV+ K+CDFG AR + T+YVATRWYRAPE
Sbjct: 115 YLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAP----GDIYTDYVATRWYRAPE 170
Query: 205 IMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGS 264
++L Y K +D+W+ GC++ E+ G P +D L++I+ +G L+ I S
Sbjct: 171 LVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPH-LQNIFS 229
Query: 265 KNVQDYIHQLGYIPKIPF----STLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYL 320
K+ I +P++ YP N +++ L DP RI+ D L H Y
Sbjct: 230 KSP---IFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYF 286
Query: 321 S 321
+
Sbjct: 287 T 287
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 129 bits (323), Expect = 1e-29
Identities = 93/320 (29%), Positives = 156/320 (48%), Gaps = 32/320 (10%)
Query: 12 FKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRS 71
F +F T F L + +G G+YG V R D A+K++ + +
Sbjct: 90 FSIFPTGATPSLTF-LFQALGKGAYGNVYRVRSLH--DGKDYALKQIMISSKNEGIPQSV 146
Query: 72 LRELKLLRHF--RGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS---GQP 126
LRE+ +++H + H NI L + P + + E + D+H +++ G P
Sbjct: 147 LREITVMKHLARKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVP 206
Query: 127 LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVE 186
A + + QI+ L ++H+ ++HRDLKP N+L+N D +K+ DFGL++ YS
Sbjct: 207 EQQAKHVTA--QIVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYS----- 259
Query: 187 NNQFLTEYVATRWYRAPEIML-SYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLN 245
N T V T WYR+PE++L SY Y +D+W+ GCI++E+ +P+F G++ +QL
Sbjct: 260 NTTAFTTLVVTLWYRSPEVLLQSY--YNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLT 317
Query: 246 RILQVLGTP-----PEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGM 300
I + +GTP P E++ I + Y L P + A+ ++
Sbjct: 318 DIFKKMGTPVGKDWPSESV--IARDSFPQY-------RPTNLKDLSPQMSKQAIEFVQQC 368
Query: 301 LSFDPQLRITVDDALQHPYL 320
L +D R++ AL HP+L
Sbjct: 369 LRYDHSKRLSARGALSHPFL 388
>YOR061w [TDK] KOG0668 Casein kinase II alpha subunit
Length = 339
Score = 127 bits (319), Expect = 4e-29
Identities = 93/318 (29%), Positives = 163/318 (51%), Gaps = 33/318 (10%)
Query: 15 FNQDFTVD----KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKR 70
+ Q T+D +++I +IG G Y V S R + + + K + K+
Sbjct: 36 YEQGVTIDWGKISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKM-------KK 88
Query: 71 SLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDA 130
RELK+L + G N+ LYD IV D L ++EE+ D + + + L D
Sbjct: 89 IYRELKILTNLTGGPNVVGLYD--IVQDADSKIPAL-IFEEIKNVDFRTLYPTFK-LPDI 144
Query: 131 HYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVN-ADCQLKICDFGLARGYSENPVENNQ 189
Y + Q+L L Y HS ++HRD+KP N++++ + +L++ D+GLA Y N +
Sbjct: 145 QY--YFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVR 202
Query: 190 FLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDYVDQLNRIL 248
VA+R+++ PE++++ Y ++D+WS GC+LA ++ K P FKG DQL +I
Sbjct: 203 -----VASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIA 257
Query: 249 QVLGTPPEETLKRIGSKNV---QDYIHQLGYIPKIPFSTLYPN----ANPDALNLLEGML 301
VLGT +E L +G + +Y + + K ++ + A P+ ++L++ +L
Sbjct: 258 TVLGT--KELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLL 315
Query: 302 SFDPQLRITVDDALQHPY 319
+D Q R+T +A+ H +
Sbjct: 316 RYDHQERLTAKEAMDHKF 333
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 127 bits (318), Expect = 5e-29
Identities = 97/301 (32%), Positives = 155/301 (51%), Gaps = 25/301 (8%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
++++G GSY V + VA+K V ++ ++ + ++RE LL+ + H NI
Sbjct: 55 LEKLGEGSYATVYKG--ISRINGQLVALK-VISMNAEEGVPFTAIREASLLKGLK-HANI 110
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAH-YQSFIYQILCGLKYI 146
L+D+ + L E M D+ Q + H + F++Q+L GL YI
Sbjct: 111 VLLHDIIHTKET------LTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYI 164
Query: 147 HSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIM 206
H VLHRDLKP NLL++ +LK+ DFGLAR S + + + +E V T WYR P+ +
Sbjct: 165 HHQHVLHRDLKPQNLLISHLGELKLADFGLARAKS---IPSQTYSSE-VVTLWYRPPDAL 220
Query: 207 LSYQGYTKAIDVWSCGCILAELLGGKPIFKG-KDYVDQLNRILQVLGTPPEETLKRIGSK 265
L Y+ +D+W GCI E+ G+P+F G + ++QL +I +VLG P E+T G
Sbjct: 221 LGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWP--GVS 278
Query: 266 NVQDYIHQLGYIPKIPFSTLYPNAN-----PDALNLLEGMLSFDPQLRITVDDALQHPYL 320
+ +Y + + P +L+ N P+A +L ML P+ R++ +AL H Y
Sbjct: 279 KLPNYNPE--WFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYF 336
Query: 321 S 321
S
Sbjct: 337 S 337
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 126 bits (317), Expect = 7e-29
Identities = 91/317 (28%), Positives = 154/317 (47%), Gaps = 35/317 (11%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
++++ + + G GSYG+V R VA+KK ++ K +LRE+++L+ +
Sbjct: 2 EKYEKLAKTGEGSYGVVFKCR--NKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLK 59
Query: 83 GHKNITCLYD-------MDIVFQ--PDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQ 133
H N+ L + M +VF+ + N L M+ D IV + + D
Sbjct: 60 -HPNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGMDSD--SIVGRLRSVADRS-- 114
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTE 193
++ I +HRD+KP N+L+ +KICDFG A+ + T+
Sbjct: 115 ----RLAPKNNQIMILQCIHRDIKPENILITKQGIIKICDFGFAQ-----ILIPGDAYTD 165
Query: 194 YVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG- 252
YVATRWYRAPE+++ Y ++D+W+ GC+ AELL G+P++ GK VDQL I++ LG
Sbjct: 166 YVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGK 225
Query: 253 -TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTL---YPNANPDALNLLEGMLSFDPQLR 308
P +++ + + H + TL + + +P ALN ++G L +P R
Sbjct: 226 LIPRHQSIFKSNG-----FFHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDR 280
Query: 309 ITVDDALQHPYLSIWHD 325
+T L+ Y + +
Sbjct: 281 LTCSQLLESSYFDSFQE 297
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 126 bits (317), Expect = 7e-29
Identities = 98/323 (30%), Positives = 155/323 (47%), Gaps = 43/323 (13%)
Query: 18 DFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKL 77
D V+ +F ++ IG GS+G V A E + + KV + F REL +
Sbjct: 30 DREVEIQFTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKS--------RELTI 81
Query: 78 LRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDM----HQIVKSGQPLTDAHYQ 133
+ H H NI L ++ Q N L E M D+ Q + + + +
Sbjct: 82 M-HEMDHPNIIRLLYYYVMQQE----NCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIK 136
Query: 134 SFIYQILCGLKYIHSADVLHRDLKPGNLLVN-ADCQLKICDFGLARGYSENPVENNQFLT 192
+++Q+L G+ ++H +++HRD+KP NLLV+ ++ LKICDFG A+ +E N+
Sbjct: 137 LYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKR-----LEKNEPNI 191
Query: 193 EYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLG 252
Y+ +R+YRAPE++ + Y +ID WS G ++ ELL PIF VD L ++ G
Sbjct: 192 TYICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFG 251
Query: 253 TPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLY---------PNANPDALNLLEGMLSF 303
TP +E + +K +Y+H IP+ T+ + L LL ++
Sbjct: 252 TPSKEDM----AKWNYEYVH-------IPYDTITGVGIQKFIGRKLSLSTLELLNSLMKM 300
Query: 304 DPQLRITVDDALQHPYLSIWHDP 326
DP+LRI +AL PY DP
Sbjct: 301 DPKLRIKPYEALTLPYFDDLRDP 323
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 126 bits (316), Expect = 9e-29
Identities = 97/303 (32%), Positives = 159/303 (52%), Gaps = 30/303 (9%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
+++Q+ + +G G Y V R D + IK + V K +C RE+ +LR+
Sbjct: 35 EKYQIYQRMGRGKYSEVFEGR----KDREKIVIKALKPV-RKAKIC----REVLILRNL- 84
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
HKNI L MD+V P+ L ++E + D +I + L + QIL
Sbjct: 85 SHKNIIKL--MDVVVDPESQIYSL-IFEYIEHEDYAKIFEK---LCYKDIVEYSRQILSA 138
Query: 143 LKYIHSADVLHRDLKPGNLLVN-ADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
L Y HS ++HRD+KP N+++N A +LKI D+GLA Y + + VA+R+Y+
Sbjct: 139 LSYCHSMGIIHRDIKPQNMVINQARRELKIIDWGLAEFYHPKKEYSVR-----VASRYYK 193
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDYVDQLNRILQVLG-TPPEETL 259
PE+++ Y Y ++D+WS GC+LAEL+ K P F G+ DQL +I ++LG T ++ +
Sbjct: 194 GPELLVDYPYYDYSLDIWSFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKKYV 253
Query: 260 KRIGSKNVQDYIHQLGYIPKIPFSTLYPNAN----PDALNLLEGMLSFDPQLRITVDDAL 315
++ + +G ++ S+ P +A++LLE +L +D Q R T D+ L
Sbjct: 254 RKYKMAPLNPKYEGVG--ERVLLSSFTPPGKTGLYTNAIDLLEKILIYDHQDRPTADECL 311
Query: 316 QHP 318
+HP
Sbjct: 312 RHP 314
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 125 bits (315), Expect = 1e-28
Identities = 89/304 (29%), Positives = 154/304 (50%), Gaps = 33/304 (10%)
Query: 29 KEIGHGSYGIVCSARFTEAADETT--VAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKN 86
K IGHGS+G V + + + E AIK+V L EL++L++ R H N
Sbjct: 45 KRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSL------ELEILQNIR-HPN 97
Query: 87 ITCLYDMDIVFQPDGMF-NGLYLYE---------ELMECDMHQIVKSGQPLTDAHYQSFI 136
+ L + F+ +G +LY+ + + ++H+ +G + H + +
Sbjct: 98 LVTL---EFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYT 154
Query: 137 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQL-KICDFGLARGYSENPVENNQFLTEYV 195
+QIL L +HS + H DLKP N+L+ + K+CDFG A+ +++N L Y
Sbjct: 155 FQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQR-----LDDNTELKTYF 209
Query: 196 ATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPP 255
+R+YRAPE++L+ + YT ID+WS GCI+ E++ G+P+FKG QL I ++LG P
Sbjct: 210 CSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFP 269
Query: 256 EETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDAL 315
+ ++K S+ +QD ++ + F +P+ + L +L++D R +
Sbjct: 270 KSSIK--NSQELQDSLNDQKF---KKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLM 324
Query: 316 QHPY 319
H +
Sbjct: 325 AHEF 328
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 125 bits (315), Expect = 1e-28
Identities = 89/309 (28%), Positives = 158/309 (50%), Gaps = 34/309 (11%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+++++++G G Y V + + + I K K+ RE+K+L++ G
Sbjct: 34 YEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKK-------KKIKREIKILQNLCGG 86
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
NI LYD + + + ++E + D + + LTD + +IY++L L
Sbjct: 87 PNIVKLYD---IVRDEHSKTPSLVFEFVNSVDFKVLYPT---LTDYDIRYYIYELLKALD 140
Query: 145 YIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+ HS ++HRD+KP N++++ + L++ D+GLA Y N + VA+R+++ P
Sbjct: 141 FCHSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPGKEYNVR-----VASRYFKGP 195
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
E+++ Q Y ++D+WS GC+ A ++ K P F G D DQL +I +VLGT L
Sbjct: 196 ELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGT---NELDHY 252
Query: 263 GSKNVQDYIHQL-----GYIPKIPFSTLYPNAN-----PDALNLLEGMLSFDPQLRITVD 312
+K D QL ++PK P+S N P+A++ L+ +L +D Q R+T
Sbjct: 253 LNKYQLDLDPQLEALVGRHVPK-PWSKFINADNQHLVSPEAIDFLDKLLQYDHQDRLTAR 311
Query: 313 DALQHPYLS 321
+A+ HPY +
Sbjct: 312 EAMDHPYFA 320
>SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 332
Score = 124 bits (312), Expect = 2e-28
Identities = 89/314 (28%), Positives = 163/314 (51%), Gaps = 30/314 (9%)
Query: 19 FTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLL 78
F +++I+++G G Y V + + IK + K + K+ RE+K+L
Sbjct: 37 FGYQDNYEIIRKVGRGKYSEVFEG--LNVLNNSKCIIKVL-----KPVKYKKIKREIKIL 89
Query: 79 RHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQ 138
++ G NI L +DIV P+ L ++E + D + + L+D + + Y+
Sbjct: 90 QNLAGGPNIISL--LDIVRDPESKTPSL-IFEFVDNIDFRTLYPT---LSDYDIRYYSYE 143
Query: 139 ILCGLKYIHSADVLHRDLKPGNLLVN-ADCQLKICDFGLARGYSENPVENNQFLTEYVAT 197
+L L + HS ++HRD+KP N++++ +L++ D+GLA Y N + VA+
Sbjct: 144 LLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEYNVR-----VAS 198
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDYVDQLNRILQVLGTPPE 256
R+++ PE+++ ++ Y ++D+WS G + A L+ K F+G+D DQL +I +VLGT +
Sbjct: 199 RYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGT--D 256
Query: 257 ETLKRIGSKNV---QDYIHQLGYIPKIPFSTLYPN-----ANPDALNLLEGMLSFDPQLR 308
E + + + Y + LG PK + + AN +A++LL +L +D Q R
Sbjct: 257 ELFAYVQKYQIVLDRQYDNILGQYPKRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQER 316
Query: 309 ITVDDALQHPYLSI 322
+T +A+ HPY +
Sbjct: 317 LTCQEAMAHPYFQV 330
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 124 bits (311), Expect = 3e-28
Identities = 90/304 (29%), Positives = 151/304 (49%), Gaps = 26/304 (8%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R++ ++ IG GS+G+V A+K+V + REL +L
Sbjct: 55 RYRYVEMIGRGSFGVVVKIMDDR---HNFFALKRVYQDR------RYHNRELGILMEV-D 104
Query: 84 HKNITCLYDMDIVFQPDGMFNGLYL--YEELMECDMHQIVKSGQPLTDAHYQSFIYQILC 141
H NI L F D +G YL + + ++ + +K+ + + +S QIL
Sbjct: 105 HPNIVRLVSY---FHTDKTSSGAYLNIITDFVGMNLEEYIKANRGVETEEIRSVYRQILE 161
Query: 142 GLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYR 201
GL+Y+H ++ HRD+KP N+L++ + +KICD G A+ +++ + Y+ +R+YR
Sbjct: 162 GLRYLHEKNICHRDMKPSNILIDTNGLVKICDLGSAK-----VIKSGERNITYICSRFYR 216
Query: 202 APEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
APE +L Y+ Y ID+WS GC++AE PIFKG LNRIL+++ ++
Sbjct: 217 APENLLDYKEYDFKIDIWSVGCVIAEFRHPGPIFKGDTSGSTLNRILEIVRVTSDDL--- 273
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
IG ++ + Q I K + ++PD L +LE L+F P R T + L+ +
Sbjct: 274 IGLGCLKPDLKQGVGIRKYLEAFF---SDPDLLEVLEKSLAFSPCKRSTASELLRKQFFQ 330
Query: 322 IWHD 325
H+
Sbjct: 331 QAHE 334
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 123 bits (308), Expect = 7e-28
Identities = 101/368 (27%), Positives = 170/368 (45%), Gaps = 83/368 (22%)
Query: 20 TVDKRFQLIKEIGHGSYGIVCSAR-------------------FTEAADETTVAIKKVTN 60
T+ R+QLI+++G GS+G V A+ + + I K
Sbjct: 33 TLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQG 92
Query: 61 VFS-KTLLCK-------RSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEEL 112
V + KT++ K +RE+K + + ++ ++++ I D L++ E
Sbjct: 93 VVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFI----DSENYQLHIVMEC 148
Query: 113 MECDMHQIVKSGQP--LTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-- 168
ME +++Q++K + + +S + QIL GLK+IH + HRDLKP N+L+ Q
Sbjct: 149 MEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYF 208
Query: 169 ---------------LKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIMLSYQGYT 213
+K+ DFGLAR VEN T YV+TRWYR+PEI+L Y+
Sbjct: 209 EKEYMNQIGYQDNYVIKLADFGLARH-----VENKNPYTAYVSTRWYRSPEILLRSGYYS 263
Query: 214 KAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEETLKRIGSKN------- 266
K +D+W+ GC+ E+ + +F G + +DQ+ +IL+VLGTP +KR N
Sbjct: 264 KPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTP----IKRSDFVNTNHITAP 319
Query: 267 --------VQDYIHQLGYIPKIPF-------STLYPNANPDALNLLEGMLSFDPQLRITV 311
+ +H+L K+P+ L + D +++ L +DP R T
Sbjct: 320 PPGGFWDDASNLVHKLNL--KLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATA 377
Query: 312 DDALQHPY 319
+ + P+
Sbjct: 378 QELCEMPF 385
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 123 bits (308), Expect = 7e-28
Identities = 79/235 (33%), Positives = 131/235 (55%), Gaps = 17/235 (7%)
Query: 23 KRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFR 82
++++ IK++G G++G V +R T +D AIKK+ V +T ++RE+KL +
Sbjct: 2 EKYENIKQVGEGAFGQVYKSRRT--SDGAVFAIKKMP-VDRETGFPFTAIREIKLCKSVI 58
Query: 83 GHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCG 142
+K+I L + IVF+ +F L E M D+ ++ SG L+ +S Q++
Sbjct: 59 -NKHIIGLDE--IVFEEGFIFVVL----EYMPYDLTGLLASGAKLSTDQIRSITSQLIEA 111
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
+ +H ++HRD+KP N+L++ LK+ DFGL R E + +T V T WYRA
Sbjct: 112 VSSMHGMGLVHRDIKPSNILLDCHGMLKLTDFGLTR-------EISGMMTNRVCTLWYRA 164
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEE 257
PE++L Y+ +D WS GCI+ E+ G+P ++G D V Q+ I + LG P ++
Sbjct: 165 PELLLGETSYSLKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQDK 219
>Hs18581346 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 121 bits (304), Expect = 2e-27
Identities = 101/338 (29%), Positives = 155/338 (44%), Gaps = 73/338 (21%)
Query: 19 FTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLL 78
F +D + +K +G G + SA + + VAIKK+ V + K +L E+K++
Sbjct: 44 FDLDSTYMDLKPLGCGGNYLFFSAVDNDC--DKRVAIKKI--VLTNPQSVKHALCEIKII 99
Query: 79 RHFRGHKNITCLYDMDIVFQPDGM-----------FNGLYLYEELMECDMHQIVKSGQPL 127
R H NI ++++ P G N +Y+ +E M+ D+ ++++ G PL
Sbjct: 100 RRL-DHDNIVKVFEIP---GPSGSQLTDDVGSLTELNSVYIVQEYMKTDLSKVLEQG-PL 154
Query: 128 TDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNA-DCQLKICDFGLARGYSENPVE 186
+ H + F+YQ+L GLKYIHSA+VLHRDLKP NL +N D LKI DFGLAR
Sbjct: 155 LEEHARLFMYQLLRGLKYIHSANVLHRDLKPTNLFINTEDLVLKIGDFGLAR-------- 206
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNR 246
+ + RA E+ +Q+
Sbjct: 207 -------IMDPHYSRAHEL------------------------------------EQMQL 223
Query: 247 ILQVLGTPPEETLKRIGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQ 306
L+ + EE + + S + YI P P + L P + +ALN LE +L+F P
Sbjct: 224 TLESIPVAHEEDRQELLSV-IPVYIRNHMTEPHKPLTQLLPGISREALNFLEQILTFSPM 282
Query: 307 LRITVDDALQHPYLSIWHDPADEPICTEKFDFSFESVN 344
+ ++AL HPY+SI P D+PI + F E+ N
Sbjct: 283 DWLIAEEALSHPYMSICSFPMDKPISSHPFHIEDEAHN 320
>CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 120 bits (300), Expect = 6e-27
Identities = 87/319 (27%), Positives = 147/319 (45%), Gaps = 37/319 (11%)
Query: 69 KRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLT 128
+R+ REL + + N+ +Y + Y+ E M M + S
Sbjct: 64 RRAQRELNCMLNIEDD-NVVKMYSTFTPAENPLKMTEFYIVREYMHGTMKNL--SASTFN 120
Query: 129 DAHYQ---SFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPV 185
+ ++ S + I G++Y+H+ + HRDLKP N+L+N + +K+CDFG + E+P
Sbjct: 121 EGGHRTVKSIFFDICRGVQYLHAMRISHRDLKPENILMNQEGDVKLCDFGHSN--KEDPT 178
Query: 186 ENNQFLTEYVATRWYRAPEIMLSYQGYTKA-IDVWSCGCILAELLGGKPIFKGKDYVDQL 244
N T Y+ R+YRAPEI+ K +D+WS GCILAELL G +F+GKD++DQ
Sbjct: 179 SN----TPYIVQRFYRAPEIICETTDNNKTNVDIWSLGCILAELLTGHVLFRGKDHIDQF 234
Query: 245 NRILQVLGTPPEETLKRIGSK--------NVQDYIHQLGYIPKIPFSTLY------PNAN 290
++Q LG ++ N+ Y + + + P + P
Sbjct: 235 ILMVQFLGNAGPSFYSQMNEHARNFLLRYNLDQYQAPINFYSRFPDTVFQGVLQFEPKEC 294
Query: 291 PDALNLLEGMLSFDPQLRITVDDALQHPYL-SIWHDPADEPICTE--------KFDFSFE 341
+ +LL ML +P R+ + L HPYL IW + E + E +F F F+
Sbjct: 295 DMSRDLLFRMLVINPDDRLNIQMVLSHPYLREIWGEIVAEDVIPEPQPPNELLRF-FDFQ 353
Query: 342 SVNEIEQLKQMVIDEVTDF 360
+ +++ + ++ +F
Sbjct: 354 PYSSPLDMREEIFQKIKNF 372
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 119 bits (299), Expect = 8e-27
Identities = 87/322 (27%), Positives = 159/322 (49%), Gaps = 26/322 (8%)
Query: 8 DRHTFKVFNQDFTVDKRFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLL 67
D ++ N + +++++++G G Y V ++ + I K
Sbjct: 17 DYWDYESLNVQWGEQDDYEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKK------ 70
Query: 68 CKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPL 127
K+ RE+K+L++ G NI L +D+V L ++E + D + + L
Sbjct: 71 -KKIRREIKILQNLCGGPNIVKL--LDVVRDQHSKTPSL-IFEYVNSTDFKVLYPT---L 123
Query: 128 TDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVE 186
TD + +IY++L L + HS ++HRD+KP N++++ + + L++ D+GLA Y
Sbjct: 124 TDYDIRYYIYELLKALDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEY 183
Query: 187 NNQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDYVDQLN 245
N + VA+R+++ PE+++ Q Y ++D+WS GC+ A ++ K P F G D DQL
Sbjct: 184 NVR-----VASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLV 238
Query: 246 RILQVLGTPPEETLKRIGSKNVQDYIHQL-GYIPKIPFSTLYPNAN-----PDALNLLEG 299
+I +VLGT + + L G + P+S N P+A++ L+
Sbjct: 239 KIAKVLGTDELNAYLNKYQLELDTQLEALVGRHSRKPWSKFINADNRHLVSPEAIDYLDK 298
Query: 300 MLSFDPQLRITVDDALQHPYLS 321
+L +D Q R+T +A+ HPY +
Sbjct: 299 LLRYDHQDRLTAKEAMAHPYFA 320
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 119 bits (297), Expect = 1e-26
Identities = 99/364 (27%), Positives = 175/364 (47%), Gaps = 56/364 (15%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R++++K IG GS+G V A + VA+K V N + +++ E+++L H R
Sbjct: 221 RYEVLKVIGKGSFGQVVKAYDHKVHQH--VALKMVRN---EKRFHRQAAEEIRILEHLRK 275
Query: 84 HKNITCLYDMDIVFQPDGMF--NGLYLYEELMECDMHQIVKSG--QPLTDAHYQSFIYQI 139
M+++ + N + + EL+ ++++++K Q + + F + I
Sbjct: 276 QDKDNT---MNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSI 332
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQ--LKICDFGLARGYSENPVENNQFLTEYVAT 197
L L +H ++H DLKP N+L+ + +K+ DFG + +Q + Y+ +
Sbjct: 333 LQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFG-------SSCYEHQRVYTYIQS 385
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEE 257
R+YRAPE++L + Y ID+WS GCILAELL G P+ G+D DQL ++++LG P ++
Sbjct: 386 RFYRAPEVILGAR-YGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQK 444
Query: 258 TLKRIGSKNVQDYIHQLGYIPKIPFSTL-------------------------YPNA--- 289
L SK ++++ GY +TL + NA
Sbjct: 445 LLD--ASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKG 502
Query: 290 --NPDALNLLEGMLSFDPQLRITVDDALQHPYL--SIWHDPADEPICTEKFDFSFESVNE 345
+P L+ L+ L +DP +R+T AL+HP+L + P E ++ S ++
Sbjct: 503 CDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTSVKRITESTGAITS 562
Query: 346 IEQL 349
I +L
Sbjct: 563 ISKL 566
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 119 bits (297), Expect = 1e-26
Identities = 99/364 (27%), Positives = 175/364 (47%), Gaps = 56/364 (15%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R++++K IG GS+G V A + VA+K V N + +++ E+++L H R
Sbjct: 148 RYEVLKVIGKGSFGQVVKAYDHKVHQH--VALKMVRN---EKRFHRQAAEEIRILEHLRK 202
Query: 84 HKNITCLYDMDIVFQPDGMF--NGLYLYEELMECDMHQIVKSG--QPLTDAHYQSFIYQI 139
M+++ + N + + EL+ ++++++K Q + + F + I
Sbjct: 203 QDKDNT---MNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSI 259
Query: 140 LCGLKYIHSADVLHRDLKPGNLLVNADCQ--LKICDFGLARGYSENPVENNQFLTEYVAT 197
L L +H ++H DLKP N+L+ + +K+ DFG + +Q + Y+ +
Sbjct: 260 LQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFG-------SSCYEHQRVYTYIQS 312
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEE 257
R+YRAPE++L + Y ID+WS GCILAELL G P+ G+D DQL ++++LG P ++
Sbjct: 313 RFYRAPEVILGAR-YGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQK 371
Query: 258 TLKRIGSKNVQDYIHQLGYIPKIPFSTL-------------------------YPNA--- 289
L SK ++++ GY +TL + NA
Sbjct: 372 LLD--ASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKG 429
Query: 290 --NPDALNLLEGMLSFDPQLRITVDDALQHPYL--SIWHDPADEPICTEKFDFSFESVNE 345
+P L+ L+ L +DP +R+T AL+HP+L + P E ++ S ++
Sbjct: 430 CDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTSVKRITESTGAITS 489
Query: 346 IEQL 349
I +L
Sbjct: 490 ISKL 493
>CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 381
Score = 119 bits (297), Expect = 1e-26
Identities = 102/342 (29%), Positives = 156/342 (44%), Gaps = 39/342 (11%)
Query: 50 ETTVAIKKVT--NVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFQPDGMFNGLY 107
E V IKKV F +R+ REL H + +N +Y + + Y
Sbjct: 40 ERRVVIKKVVLPENFDNWQHWRRAQRELFCTLHIQ-EENFVKMYSIYTWVETVEEMREFY 98
Query: 108 LYEELMECDMHQ-IVKSGQPLTDAHYQSFIYQILCGLKYIHSADVLHRDLKPGNLLVNAD 166
E M+ ++ I+ + + L +S + + ++Y+HS V HRDLKP N+L+N +
Sbjct: 99 TVREYMDWNLRNFILSTPEKLDHKVIKSIFFDVCLAVQYMHSIRVGHRDLKPENVLINYE 158
Query: 167 CQLKICDFGLARGYSENPVENNQFLTEYVATRWYRAPEIMLSYQGYTK-AIDVWSCGCIL 225
KI G A E+P N T Y+ R+YRAPEI+ K ++D+WS GCIL
Sbjct: 159 AIAKIS--GFAHANREDPFVN----TPYIVQRFYRAPEILCETMDNNKPSVDIWSLGCIL 212
Query: 226 AELLGGKPIFKGKDYVDQLNRILQVLGTP--------PEETLKRIGSKNVQDY-----IH 272
AELL GK +F G+ +DQ +I++ LG P P+ + Y IH
Sbjct: 213 AELLTGKILFTGQTQIDQFFQIVRFLGNPDLSFYMQMPDSARTFFLGLPMNQYQKPTNIH 272
Query: 273 QLGYIPKIPFSTLYPNANPD---ALNLLEGMLSFDPQLRITVDDALQHPYL-SIWHDPAD 328
+ + P F + D A +LL ML +P RI + L HPYL +W +
Sbjct: 273 E--HFPNSLFLDTMISEPIDCDLARDLLFRMLVINPDDRIDIQKILVHPYLEEVWSNIVI 330
Query: 329 E--------PICTEKFDFSFESVNEIEQLKQMVIDEVTDFRQ 362
+ PI +F F F++ + Q+K + +T+F Q
Sbjct: 331 DNKIEEKYPPIALRRF-FEFQAFSPPRQMKDEIFSTLTEFGQ 371
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 118 bits (296), Expect = 2e-26
Identities = 84/305 (27%), Positives = 154/305 (49%), Gaps = 26/305 (8%)
Query: 25 FQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGH 84
+++++++G G Y V + ++ + I K K+ RE+K+L++ G
Sbjct: 34 YEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKK-------KKIRREIKILQNLCGG 86
Query: 85 KNITCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKSGQPLTDAHYQSFIYQILCGLK 144
NI L +D+V L ++E + D + + LTD + +IY++L L
Sbjct: 87 PNIVKL--LDVVRDQHSKTPSL-IFEYVNSTDFKVLYPT---LTDYDIRYYIYELLKALD 140
Query: 145 YIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENNQFLTEYVATRWYRAP 203
+ HS ++HRD+KP N++++ + + L++ D+GLA Y N + VA+R+++ P
Sbjct: 141 FCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVR-----VASRYFKGP 195
Query: 204 EIMLSYQGYTKAIDVWSCGCILAELLGGK-PIFKGKDYVDQLNRILQVLGTPPEETLKRI 262
E+++ Q Y ++D+WS GC+ A ++ K P F G D DQL +I +VLGT
Sbjct: 196 ELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNK 255
Query: 263 GSKNVQDYIHQL-GYIPKIPFSTLYPNAN-----PDALNLLEGMLSFDPQLRITVDDALQ 316
+ + L G + P+S N P+A++ L+ +L +D Q R+T +A+
Sbjct: 256 YQLELDPQLEALVGRHSRKPWSKFINADNQHLVSPEAIDFLDKLLRYDHQDRLTAKEAMA 315
Query: 317 HPYLS 321
H Y +
Sbjct: 316 HAYFA 320
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 117 bits (293), Expect = 4e-26
Identities = 97/335 (28%), Positives = 163/335 (47%), Gaps = 56/335 (16%)
Query: 24 RFQLIKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRG 83
R++++K IG GS+G V AR + VA+K V N + +++ E+++L H +
Sbjct: 173 RYEVLKIIGKGSFGQV--ARVYDHKLRQYVALKMVRN---EKRFHRQAAEEIRILEHLKK 227
Query: 84 HKNITCLYDMDIVFQPDGMF--NGLYLYEELMECDMHQIVKSG--QPLTDAHYQSFIYQI 139
M+++ + N + + EL+ D+++++K Q + + F I
Sbjct: 228 QDKTG---SMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSI 284
Query: 140 LCGLKYIHSADVLHRDLKPGNLLV--NADCQLKICDFGLARGYSENPVENNQFLTEYVAT 197
L L +H ++H DLKP N+L+ + K+ DFG + Q L Y+ +
Sbjct: 285 LQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFG-------SSCFEYQKLYTYIQS 337
Query: 198 RWYRAPEIMLSYQGYTKAIDVWSCGCILAELLGGKPIFKGKDYVDQLNRILQVLGTPPEE 257
R+YRAPEI+L + Y+ ID+WS CILAELL G+P+F G+D DQL ++++LG PP +
Sbjct: 338 RFYRAPEIILGSR-YSTPIDIWSFRCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPK 396
Query: 258 TLKRIGSKNVQDYIHQLGYIPKIPFSTLY-------------------PNANPD------ 292
L++ SK + +I+ G IP+ T P + D
Sbjct: 397 LLEQ--SKRAKYFINSKG-IPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALK 453
Query: 293 ------ALNLLEGMLSFDPQLRITVDDALQHPYLS 321
+ L+ L +DP R+T AL+HP++S
Sbjct: 454 GCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWIS 488
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 117 bits (293), Expect = 4e-26
Identities = 94/305 (30%), Positives = 146/305 (47%), Gaps = 39/305 (12%)
Query: 28 IKEIGHGSYGIVCSARFTEAADETTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 87
+++IG G+YG V A+ E + VA+K V + + +LRE+ LL+ + HKNI
Sbjct: 78 LEKIGEGTYGTVFKAKNWETHE--IVALKWVRLDDNDDGVPSSALREICLLKELK-HKNI 134
Query: 88 TCLYDMDIVFQPDGMFNGLYLYEELMECDMHQIVKS-----GQPLTDAHYQSFIYQILCG 142
L+D+ D ++ + HQ +K L +SF++Q+L G
Sbjct: 135 VRLHDL---LHSDKKLTLVFKF-------CHQHLKKYFDSCNGDLDPEIVKSFLFQLLKG 184
Query: 143 LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENNQFLTEYVATRWYRA 202
L + HS +VL RDLKP NLL+N + +LK+ DFGL+R +
Sbjct: 185 LGFCHSRNVLRRDLKPQNLLINRNGELKLADFGLSRAFG------------------IPI 226
Query: 203 PEIMLSYQGYTKAIDVWSCGCILAELL-GGKPIFKGKDYVDQLNRILQVLGTPPEETLKR 261
+ + Y+ +ID+WS GCI AEL G P+F G D DQL RI +LG +E
Sbjct: 227 CYVFFGAKLYSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFWLLGMLTKEQWPS 286
Query: 262 IGSKNVQDYIHQLGYIPKIPFSTLYPNANPDALNLLEGMLSFDPQLRITVDDALQHPYLS 321
+ + DY Y + P + +LL+ +L +P I+ ++ALQ+PY S
Sbjct: 287 M--TKLPDYKLYPLYPATTSLVNIVPKLSATGRDLLQNLLKCNPCQCISAEEALQYPYFS 344
Query: 322 IWHDP 326
+ P
Sbjct: 345 DFCPP 349
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,691,777
Number of Sequences: 60738
Number of extensions: 1482173
Number of successful extensions: 8676
Number of sequences better than 1.0e-05: 1552
Number of HSP's better than 0.0 without gapping: 377
Number of HSP's successfully gapped in prelim test: 1175
Number of HSP's that attempted gapping in prelim test: 5537
Number of HSP's gapped (non-prelim): 2036
length of query: 495
length of database: 30,389,216
effective HSP length: 110
effective length of query: 385
effective length of database: 23,708,036
effective search space: 9127593860
effective search space used: 9127593860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)