ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3043 check: MH T KOG0660 Signal transduction mechanisms Mitogen-activated protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3043 1049352 1048036 -439
(439 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR054w [T] KOG0660 Mitogen-activated protein kinase 473 e-133
YHR030c [T] KOG0660 Mitogen-activated protein kinase 307 2e-83
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 293 3e-79
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 263 3e-70
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 263 4e-70
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 263 4e-70
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 263 4e-70
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 263 5e-70
CE24971 [T] KOG0660 Mitogen-activated protein kinase 249 6e-66
CE01583 [T] KOG0660 Mitogen-activated protein kinase 249 6e-66
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 246 5e-65
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 244 1e-64
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 242 7e-64
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 241 1e-63
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 241 2e-63
YBL016w [T] KOG0660 Mitogen-activated protein kinase 241 2e-63
YGR040w [T] KOG0660 Mitogen-activated protein kinase 240 3e-63
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 236 7e-62
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 234 1e-61
YKL161c [T] KOG0660 Mitogen-activated protein kinase 233 3e-61
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 233 6e-61
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 232 7e-61
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 230 3e-60
7301110 [T] KOG0660 Mitogen-activated protein kinase 230 4e-60
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 228 1e-59
YLR113w [T] KOG0660 Mitogen-activated protein kinase 227 3e-59
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 226 4e-59
CE06762 [T] KOG0660 Mitogen-activated protein kinase 221 1e-57
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 218 1e-56
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 217 2e-56
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 217 2e-56
7298087 [T] KOG0660 Mitogen-activated protein kinase 217 2e-56
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 216 7e-56
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 215 9e-56
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 214 3e-55
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 212 8e-55
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 211 1e-54
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 211 2e-54
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 210 4e-54
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 206 4e-53
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 204 2e-52
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 204 2e-52
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 203 5e-52
CE06686 [T] KOG0660 Mitogen-activated protein kinase 202 1e-51
CE29020 [T] KOG0660 Mitogen-activated protein kinase 200 3e-51
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 199 5e-51
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 199 7e-51
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 199 7e-51
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 194 2e-49
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 190 3e-48
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 190 3e-48
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 190 3e-48
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 187 2e-47
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 187 2e-47
7291043 [T] KOG0660 Mitogen-activated protein kinase 187 2e-47
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 186 5e-47
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 185 1e-46
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 185 1e-46
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 185 1e-46
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 183 4e-46
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 183 5e-46
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 183 5e-46
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 182 9e-46
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 179 7e-45
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 179 1e-44
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 179 1e-44
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 177 4e-44
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 176 6e-44
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 176 6e-44
CE29318 [T] KOG0660 Mitogen-activated protein kinase 175 1e-43
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 174 2e-43
CE17062 [T] KOG0660 Mitogen-activated protein kinase 174 3e-43
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 173 4e-43
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 172 7e-43
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 172 9e-43
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 172 9e-43
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 171 2e-42
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 171 3e-42
CE26422 [D] KOG0600 Cdc2-related protein kinase 170 4e-42
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 169 6e-42
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 169 6e-42
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 169 8e-42
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 169 8e-42
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 169 1e-41
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 169 1e-41
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 166 5e-41
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 165 1e-40
7296451 [D] KOG0600 Cdc2-related protein kinase 165 1e-40
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 165 1e-40
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 164 2e-40
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 164 2e-40
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 164 2e-40
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 164 2e-40
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 163 5e-40
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 162 9e-40
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 162 1e-39
YPR161c [D] KOG0600 Cdc2-related protein kinase 161 2e-39
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 161 2e-39
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 161 2e-39
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 159 6e-39
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 159 8e-39
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 157 2e-38
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 157 2e-38
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 157 3e-38
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 157 3e-38
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 157 4e-38
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 157 4e-38
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 157 4e-38
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 157 4e-38
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 155 9e-38
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 155 1e-37
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 3e-37
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 153 6e-37
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 152 7e-37
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 152 7e-37
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 152 7e-37
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 152 7e-37
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 152 1e-36
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 152 1e-36
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 152 1e-36
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 152 1e-36
CE27220 [T] KOG0660 Mitogen-activated protein kinase 151 2e-36
CE21401 [G] KOG0658 Glycogen synthase kinase-3 151 2e-36
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 151 2e-36
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 151 2e-36
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 151 2e-36
At5g10270 [D] KOG0600 Cdc2-related protein kinase 151 2e-36
At5g64960 [D] KOG0600 Cdc2-related protein kinase 150 3e-36
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 150 4e-36
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 6e-36
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 8e-36
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 149 1e-35
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 148 1e-35
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 2e-35
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 2e-35
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 147 2e-35
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 147 3e-35
At1g33770 [D] KOG0600 Cdc2-related protein kinase 147 3e-35
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 146 5e-35
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 146 7e-35
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 146 7e-35
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 145 9e-35
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 145 9e-35
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 145 1e-34
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 145 1e-34
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 145 1e-34
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 145 2e-34
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 2e-34
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 2e-34
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 2e-34
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 2e-34
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 2e-34
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 145 2e-34
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 145 2e-34
YNL307c [G] KOG0658 Glycogen synthase kinase-3 144 2e-34
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 144 2e-34
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 144 3e-34
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 144 3e-34
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 144 3e-34
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 144 3e-34
At1g53050 [D] KOG0600 Cdc2-related protein kinase 143 4e-34
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 143 4e-34
At1g03740 [D] KOG0600 Cdc2-related protein kinase 143 4e-34
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 143 6e-34
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 143 6e-34
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 143 6e-34
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 143 6e-34
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 143 6e-34
7290342 [G] KOG0658 Glycogen synthase kinase-3 142 8e-34
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 1e-33
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 142 1e-33
YKL139w [D] KOG0600 Cdc2-related protein kinase 142 1e-33
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 141 2e-33
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 141 2e-33
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 141 2e-33
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 140 3e-33
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 139 6e-33
At5g39420 [D] KOG0600 Cdc2-related protein kinase 139 8e-33
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 139 1e-32
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 139 1e-32
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 138 1e-32
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 138 2e-32
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 137 2e-32
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 137 3e-32
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 137 3e-32
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 136 5e-32
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 135 9e-32
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 135 1e-31
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 135 1e-31
YMR139w [G] KOG0658 Glycogen synthase kinase-3 135 2e-31
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 135 2e-31
At5g44290 [D] KOG0600 Cdc2-related protein kinase 135 2e-31
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 134 2e-31
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 134 4e-31
At4g22940 [D] KOG0600 Cdc2-related protein kinase 133 5e-31
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 133 5e-31
At1g09600 [D] KOG0600 Cdc2-related protein kinase 133 6e-31
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 132 8e-31
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 132 1e-30
At1g54610 [D] KOG0600 Cdc2-related protein kinase 132 1e-30
At4g10010 [D] KOG0600 Cdc2-related protein kinase 131 2e-30
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 130 4e-30
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 129 7e-30
At3g05050 [D] KOG0600 Cdc2-related protein kinase 129 7e-30
At1g71530 [D] KOG0600 Cdc2-related protein kinase 129 7e-30
CE08727 [G] KOG0658 Glycogen synthase kinase-3 129 9e-30
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 129 9e-30
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 128 2e-29
At5g50860 [D] KOG0600 Cdc2-related protein kinase 127 3e-29
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 126 6e-29
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 126 6e-29
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 126 7e-29
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 125 1e-28
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 125 2e-28
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 125 2e-28
At1g57700 [D] KOG0600 Cdc2-related protein kinase 125 2e-28
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 124 2e-28
At1g74330 [D] KOG0600 Cdc2-related protein kinase 124 2e-28
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 124 2e-28
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 124 4e-28
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 123 6e-28
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 122 1e-27
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 122 1e-27
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 122 1e-27
At1g18670 [D] KOG0600 Cdc2-related protein kinase 122 1e-27
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 120 3e-27
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 120 3e-27
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 120 3e-27
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 120 5e-27
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 119 7e-27
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 119 7e-27
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 119 7e-27
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 119 7e-27
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 117 3e-26
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 117 4e-26
YDL079c [G] KOG0658 Glycogen synthase kinase-3 115 1e-25
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 115 1e-25
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 115 2e-25
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 114 3e-25
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 114 4e-25
YOL128c [G] KOG0658 Glycogen synthase kinase-3 113 5e-25
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 113 6e-25
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 113 6e-25
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 8e-25
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 8e-25
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 112 1e-24
CE05866 [G] KOG0658 Glycogen synthase kinase-3 111 2e-24
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 111 2e-24
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 3e-23
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 107 5e-23
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 106 6e-23
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 106 8e-23
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 8e-23
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 8e-23
CE09532 [G] KOG0658 Glycogen synthase kinase-3 105 1e-22
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 105 1e-22
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 104 2e-22
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 104 2e-22
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 2e-22
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 103 4e-22
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 103 5e-22
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 103 7e-22
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 103 7e-22
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 103 7e-22
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 101 2e-21
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 101 3e-21
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 101 3e-21
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 101 3e-21
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 100 4e-21
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 4e-21
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 100 4e-21
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 6e-21
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 100 7e-21
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 99 1e-20
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 1e-20
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 99 1e-20
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 98 2e-20
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 98 2e-20
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 97 4e-20
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 97 4e-20
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 97 4e-20
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 97 4e-20
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 97 5e-20
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 96 8e-20
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 96 1e-19
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 96 1e-19
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 96 1e-19
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 96 1e-19
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 95 2e-19
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 95 2e-19
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 95 2e-19
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 95 2e-19
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 95 2e-19
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 94 4e-19
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 4e-19
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 94 4e-19
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 94 5e-19
CE01612 [G] KOG0658 Glycogen synthase kinase-3 94 5e-19
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 5e-19
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 93 7e-19
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 93 7e-19
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 93 7e-19
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 93 9e-19
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 93 9e-19
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 93 9e-19
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 93 9e-19
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 92 1e-18
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 92 1e-18
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 92 2e-18
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 92 2e-18
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 2e-18
CE20405 [G] KOG0658 Glycogen synthase kinase-3 92 2e-18
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 92 2e-18
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 92 2e-18
7301719 [T] KOG0671 LAMMER dual specificity kinases 92 2e-18
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 91 3e-18
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 91 3e-18
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 91 4e-18
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 4e-18
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 90 6e-18
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 90 6e-18
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 90 8e-18
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 90 8e-18
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 89 1e-17
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 89 1e-17
7299793 [T] KOG0583 Serine/threonine protein kinase 89 1e-17
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 89 1e-17
YDL028c [D] KOG0596 Dual specificity; serine/threonine and tyros... 89 1e-17
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 89 1e-17
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 1e-17
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 89 1e-17
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 89 1e-17
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 89 1e-17
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 89 2e-17
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 89 2e-17
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 89 2e-17
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 89 2e-17
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 89 2e-17
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 88 2e-17
7300559 [T] KOG4279 Serine/threonine protein kinase 88 2e-17
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 88 3e-17
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 88 3e-17
Hs18677726 [T] KOG1151 Tousled-like protein kinase 88 3e-17
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 88 3e-17
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 87 4e-17
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 87 4e-17
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 4e-17
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 87 4e-17
CE27177 [T] KOG4279 Serine/threonine protein kinase 87 4e-17
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 87 4e-17
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 87 5e-17
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 87 5e-17
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 5e-17
7298004 [G] KOG0658 Glycogen synthase kinase-3 87 5e-17
CE18699 [T] KOG0694 Serine/threonine protein kinase 87 6e-17
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 87 6e-17
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 86 8e-17
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 86 8e-17
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 86 8e-17
CE05377 [G] KOG0658 Glycogen synthase kinase-3 86 8e-17
CE01405 [T] KOG0577 Serine/threonine protein kinase 86 8e-17
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 86 1e-16
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 86 1e-16
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 86 1e-16
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 86 1e-16
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 86 1e-16
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 86 1e-16
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 86 1e-16
Hs18581346 [T] KOG0660 Mitogen-activated protein kinase 86 1e-16
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 86 1e-16
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 85 2e-16
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 85 2e-16
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 85 2e-16
Hs11140819 [T] KOG1151 Tousled-like protein kinase 85 2e-16
ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and ty... 85 2e-16
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 85 2e-16
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 85 2e-16
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 85 2e-16
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 85 2e-16
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 85 2e-16
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 85 2e-16
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 85 2e-16
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 85 2e-16
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 85 2e-16
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 85 2e-16
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 85 2e-16
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 85 2e-16
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 85 2e-16
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 85 2e-16
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 84 3e-16
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 84 3e-16
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 84 3e-16
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 84 3e-16
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 3e-16
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 84 4e-16
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 84 4e-16
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 84 4e-16
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 84 4e-16
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 84 4e-16
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 84 4e-16
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 84 4e-16
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 84 5e-16
At1g54510 [R] KOG0589 Serine/threonine protein kinase 84 5e-16
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 84 5e-16
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 83 7e-16
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 83 7e-16
CE17354 [T] KOG0694 Serine/threonine protein kinase 83 7e-16
CE17353 [T] KOG0694 Serine/threonine protein kinase 83 7e-16
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 7e-16
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 83 7e-16
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 83 9e-16
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 83 9e-16
CE23001 [R] KOG0589 Serine/threonine protein kinase 83 9e-16
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 83 9e-16
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 82 1e-15
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 82 1e-15
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 82 1e-15
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 82 1e-15
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 1e-15
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 82 1e-15
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 82 2e-15
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 82 2e-15
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 82 2e-15
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 82 2e-15
7290436 [T] KOG1151 Tousled-like protein kinase 82 2e-15
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 82 2e-15
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 82 2e-15
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 82 2e-15
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 82 2e-15
CE27768 [R] KOG0586 Serine/threonine protein kinase 82 2e-15
CE23838 [R] KOG0586 Serine/threonine protein kinase 82 2e-15
At3g20860 [R] KOG0589 Serine/threonine protein kinase 82 2e-15
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 81 3e-15
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 81 3e-15
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 81 3e-15
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 81 3e-15
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 3e-15
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 81 4e-15
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 81 4e-15
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 81 4e-15
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 81 4e-15
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 81 4e-15
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 4e-15
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 81 4e-15
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 80 5e-15
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 80 5e-15
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 80 5e-15
CE23524 [T] KOG1151 Tousled-like protein kinase 80 5e-15
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 80 5e-15
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 80 5e-15
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 80 6e-15
YDR477w [T] KOG0583 Serine/threonine protein kinase 80 6e-15
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 6e-15
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 80 6e-15
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 80 6e-15
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 80 6e-15
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 80 8e-15
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 80 8e-15
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 80 8e-15
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 80 8e-15
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 79 1e-14
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 1e-14
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 79 1e-14
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 79 1e-14
At5g28290 [R] KOG0589 Serine/threonine protein kinase 79 1e-14
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 79 1e-14
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 79 1e-14
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 79 2e-14
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 79 2e-14
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 79 2e-14
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 2e-14
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 79 2e-14
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 473 bits (1216), Expect = e-133
Identities = 225/361 (62%), Positives = 283/361 (78%), Gaps = 3/361 (0%)
Query: 58 KRSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILL 117
+R+I++ S+PG YEI+Q LGKG+YGTV S KG + ++A+KK+++IF +EILL
Sbjct: 23 QRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGR-SPAARIAVKKISNIFNKEILL 81
Query: 118 KRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEF 177
KRAIRELKFM++FKGH+NIV+LIDLEIV PY GLYCYQEL+DYDLA+VIHS+V SEF
Sbjct: 82 KRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEF 141
Query: 178 HIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPS-FTVAGG 236
HIK+FLYQILCG+KYIHSADVIHRDLKPGNILC++ G +KICDFGLARGI F
Sbjct: 142 HIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHST 201
Query: 237 ISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVME 296
+ HITNYVATRWYRAPEL+LS++ YSKSVD+WAVGCILAEFY RKPVFMG DS+HQ+ E
Sbjct: 202 VQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFE 261
Query: 297 IQKILGTPKQIVIRTYGSSRCYDIFSTS-KPQYKKTPWCEIFPYASSEAVDLMERLIDWN 355
I K+LGTP + ++ +G+ + +++ S P YKK PW IFP+AS EA++L+E L+ W+
Sbjct: 262 IIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWD 321
Query: 356 PEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHN 415
RL VE+A+ HPFL +VR P+ EP+C GPFDFTYE L SM +LR+ L +EV F
Sbjct: 322 STHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNFKT 381
Query: 416 D 416
D
Sbjct: 382 D 382
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 307 bits (787), Expect = 2e-83
Identities = 157/365 (43%), Positives = 245/365 (67%), Gaps = 15/365 (4%)
Query: 66 NFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELK 125
+FSV R+++++ +G G+YG V SA + +AIKKVT++F++ +L KR++RELK
Sbjct: 16 DFSVDKRFQLIKEIGHGAYGIVCSA-RFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELK 74
Query: 126 FMSYFKGHRNIVSLIDLEIV--NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFL 183
+ +F+GH+NI L D++IV + +GLY Y+EL++ D+ ++I S ++ H + F
Sbjct: 75 LLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFT 134
Query: 184 YQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITN 243
YQILCG+KYIHSADV+HRDLKPGN+L + ++KICDFGLARG S + S +T
Sbjct: 135 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVEN---SQFLTE 191
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGT 303
YVATRWYRAPE++LS++ Y+K++D+W+ GCILAEF G KP+F G D ++Q+ +I ++LGT
Sbjct: 192 YVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGT 251
Query: 304 PKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVE 363
P +R GS D + K P+ ++P A+S+A+DL+E+++ ++P+ R+TV+
Sbjct: 252 PPDETLRRIGSKNVQD-YIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVD 310
Query: 364 EALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFV 423
EAL+HP+L +P EP+C F+F++E + ME L++ + EV F + FV
Sbjct: 311 EALEHPYLSIWHDPADEPVCSE-KFEFSFES-VNDMEDLKQMVIQEVQDF------RLFV 362
Query: 424 SPPLM 428
PL+
Sbjct: 363 RQPLL 367
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 293 bits (750), Expect = 3e-79
Identities = 151/358 (42%), Positives = 231/358 (64%), Gaps = 7/358 (1%)
Query: 69 VPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMS 128
V +++++ LG+G+YG V +A + + E +AIKK+T++F++ IL KRA+RE+K +
Sbjct: 17 VEPNFKVVKELGQGAYGIVCAARNVASKDQEA-VAIKKITNVFSKSILTKRALREIKLLI 75
Query: 129 YFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILC 188
+F+ HRNI + DL+I+N ++ +Y Y+EL++ DL +I S ++ H + F+YQILC
Sbjct: 76 HFRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQILC 135
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
G+KYIHSA+VIHRDLKPGN+L + E+KICDFGLARG S + G +T YVATR
Sbjct: 136 GLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGF---MTEYVATR 192
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYRAPE++LS Y K +D+W+VGCILAE G P+F G D +HQ+ I LGTP +
Sbjct: 193 WYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEET 252
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
+ SSR + + S P+ + P+ FP A+ A+DL+ +L+ ++P R++V++AL+H
Sbjct: 253 LSHISSSRAQE-YVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDALEH 311
Query: 369 PFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFVSPP 426
P+L +P EP+C FDF++E ++ LR + DEV F + + + P
Sbjct: 312 PYLAVWHDPSDEPVC-DSVFDFSFE-YIEDANELRRVILDEVLNFRQKVRRRSHPTNP 367
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 263 bits (673), Expect = 3e-70
Identities = 146/348 (41%), Positives = 217/348 (61%), Gaps = 13/348 (3%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F V RY L +G+G+YG V SA D N +V++AIKK+ S F + +R +RE+K
Sbjct: 19 FDVGPRYTNLSYIGEGAYGMVCSAYDNVN---KVRVAIKKI-SPFEHQTYCQRTLREIKI 74
Query: 127 MSYFKGHRNIVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ F+ H NI+ + D+ E +Y Q+L++ DL +++ + L ++ HI +FLYQ
Sbjct: 75 LLRFR-HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-HICYFLYQ 132
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
IL G+KYIHSA+V+HRDLKP N+L + T ++KICDFGLAR P G +T YV
Sbjct: 133 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG----FLTEYV 188
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
ATRWYRAPE++L+ K Y+KS+D+W+VGCILAE +P+F G L Q+ I ILG+P
Sbjct: 189 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPS 248
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
Q + + + + + S P K PW +FP A S+A+DL+++++ +NP R+ VE+A
Sbjct: 249 QEDLNCIINLKARN-YLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQA 307
Query: 366 LDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKF 413
L HP+L+Q +P EPI PF F E E+L+E + +E ++F
Sbjct: 308 LAHPYLEQYYDPSDEPIA-EAPFKFDMELDDLPKEKLKELIFEETARF 354
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 263 bits (672), Expect = 4e-70
Identities = 146/348 (41%), Positives = 217/348 (61%), Gaps = 13/348 (3%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F V RY L +G+G+YG V SA D N +V++AIKK+ S F + +R +RE+K
Sbjct: 19 FDVGPRYTNLSYIGEGAYGMVCSAYDNVN---KVRVAIKKI-SPFEHQTYCQRTLREIKI 74
Query: 127 MSYFKGHRNIVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ F+ H NI+ + D+ E +Y Q+L++ DL +++ + L ++ HI +FLYQ
Sbjct: 75 LLRFR-HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-HICYFLYQ 132
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
IL G+KYIHSA+V+HRDLKP N+L + T ++KICDFGLAR P G +T YV
Sbjct: 133 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG----FLTEYV 188
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
ATRWYRAPE++L+ K Y+KS+D+W+VGCILAE +P+F G L Q+ I ILG+P
Sbjct: 189 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPS 248
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
Q + + + + + S P K PW +FP A S+A+DL+++++ +NP R+ VE+A
Sbjct: 249 QEDLNCIINLKARN-YLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQA 307
Query: 366 LDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKF 413
L HP+L+Q +P EPI PF F E E+L+E + +E ++F
Sbjct: 308 LAHPYLEQYYDPSDEPIA-EAPFKFDMELDDLPKEKLKELIFEETARF 354
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 263 bits (672), Expect = 4e-70
Identities = 141/354 (39%), Positives = 217/354 (60%), Gaps = 11/354 (3%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F V YEI++ +G G+YG V SA + T + Q+AIKK+ + F KR +RELK
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSA--RRRLTGQ-QVAIKKIPNAFDVVTNAKRTLRELKI 105
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ +FK H NI+++ D+ V + +Y +L++ DL ++IHS+ + H+++FLY
Sbjct: 106 LKHFK-HDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLY 164
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q+L G+KY+HSA VIHRDLKP N+L + E+KI DFG+ARG+ S +T Y
Sbjct: 165 QLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTS---PAEHQYFMTEY 221
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYRAPEL+LS Y++++D+W+VGCI E R+ +F G + +HQ+ I +LGTP
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTP 281
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
VI+ G+ R + S P + PW ++P A +A+ L+ R++ + P AR++
Sbjct: 282 SPAVIQAVGAER-VRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAA 340
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQ 418
AL HPFL + +P+ EP C PFDF +++ + ER++E + E+ FH R+
Sbjct: 341 ALRHPFLAKYHDPDDEPDCA-PPFDFAFDREALTRERIKEAIVAEIEDFHARRE 393
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 263 bits (672), Expect = 4e-70
Identities = 141/354 (39%), Positives = 217/354 (60%), Gaps = 11/354 (3%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F V YEI++ +G G+YG V SA + T + Q+AIKK+ + F KR +RELK
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSA--RRRLTGQ-QVAIKKIPNAFDVVTNAKRTLRELKI 105
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ +FK H NI+++ D+ V + +Y +L++ DL ++IHS+ + H+++FLY
Sbjct: 106 LKHFK-HDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLY 164
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q+L G+KY+HSA VIHRDLKP N+L + E+KI DFG+ARG+ S +T Y
Sbjct: 165 QLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTS---PAEHQYFMTEY 221
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYRAPEL+LS Y++++D+W+VGCI E R+ +F G + +HQ+ I +LGTP
Sbjct: 222 VATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTP 281
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
VI+ G+ R + S P + PW ++P A +A+ L+ R++ + P AR++
Sbjct: 282 SPAVIQAVGAER-VRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAA 340
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQ 418
AL HPFL + +P+ EP C PFDF +++ + ER++E + E+ FH R+
Sbjct: 341 ALRHPFLAKYHDPDDEPDCA-PPFDFAFDREALTRERIKEAIVAEIEDFHARRE 393
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 263 bits (671), Expect = 5e-70
Identities = 147/348 (42%), Positives = 216/348 (61%), Gaps = 13/348 (3%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F V RY LQ +G+G+YG V SA D T ++AIKK+ S F + +R +RE++
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKT---RVAIKKI-SPFEHQTYCQRTLREIQI 91
Query: 127 MSYFKGHRNIVSLID-LEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ F+ H N++ + D L E +Y Q+L++ DL +++ S L ++ HI +FLYQ
Sbjct: 92 LLRFR-HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSND-HICYFLYQ 149
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
IL G+KYIHSA+V+HRDLKP N+L + T ++KICDFGLAR P G +T YV
Sbjct: 150 ILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTG----FLTEYV 205
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
ATRWYRAPE++L+ K Y+KS+D+W+VGCILAE +P+F G L Q+ I ILG+P
Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPS 265
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
Q + + + + + S P K W ++FP + S+A+DL++R++ +NP R+TVEEA
Sbjct: 266 QEDLNCIINMKARN-YLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEA 324
Query: 366 LDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKF 413
L HP+L+Q +P EP+ PF F E ERL+E + E ++F
Sbjct: 325 LAHPYLEQYYDPTDEPVAEE-PFTFAMELDDLPKERLKELIFQETARF 371
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 249 bits (636), Expect = 6e-66
Identities = 139/351 (39%), Positives = 212/351 (59%), Gaps = 17/351 (4%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F V RY L +G+G+YG V SA+D ++AIKK+ S F + +R +RE+K
Sbjct: 90 FEVAPRYVNLSYIGEGAYGMVASALDT---ITRDRVAIKKI-SPFEHQTFCQRTLREIKI 145
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGL---YCYQELVDYDLARVIHSNVLFSEFHIKHFL 183
++ FK H NI+++ EI+ E L Y Q L++ DL +++ + L ++ H+ +FL
Sbjct: 146 LNRFK-HENIINI--QEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSND-HVCYFL 201
Query: 184 YQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITN 243
YQIL G+KYIHSA+V+HRDLKP N+L + T ++KICDFGLAR P G +T
Sbjct: 202 YQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTG----FLTE 257
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGT 303
YVATRWYRAPE++L+ K Y+KS+D+W+VGCILAE +P+F G L Q+ I ++G+
Sbjct: 258 YVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGS 317
Query: 304 PKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVE 363
P ++ + + + S P K PW ++P A A+DL+++++ +NP R+ +E
Sbjct: 318 PSNADLQCIINDKARS-YLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIE 376
Query: 364 EALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
+AL HP+L+Q +P EP+C PF E E+L+E + +E H
Sbjct: 377 QALAHPYLEQYYDPGDEPVCEE-PFTLEMEFDDLPKEKLKELIWEEAEAHH 426
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 249 bits (636), Expect = 6e-66
Identities = 139/351 (39%), Positives = 212/351 (59%), Gaps = 17/351 (4%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F V RY L +G+G+YG V SA+D ++AIKK+ S F + +R +RE+K
Sbjct: 22 FEVAPRYVNLSYIGEGAYGMVASALDT---ITRDRVAIKKI-SPFEHQTFCQRTLREIKI 77
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGL---YCYQELVDYDLARVIHSNVLFSEFHIKHFL 183
++ FK H NI+++ EI+ E L Y Q L++ DL +++ + L ++ H+ +FL
Sbjct: 78 LNRFK-HENIINI--QEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSND-HVCYFL 133
Query: 184 YQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITN 243
YQIL G+KYIHSA+V+HRDLKP N+L + T ++KICDFGLAR P G +T
Sbjct: 134 YQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTG----FLTE 189
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGT 303
YVATRWYRAPE++L+ K Y+KS+D+W+VGCILAE +P+F G L Q+ I ++G+
Sbjct: 190 YVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGS 249
Query: 304 PKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVE 363
P ++ + + + S P K PW ++P A A+DL+++++ +NP R+ +E
Sbjct: 250 PSNADLQCIINDKARS-YLISLPHKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIE 308
Query: 364 EALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
+AL HP+L+Q +P EP+C PF E E+L+E + +E H
Sbjct: 309 QALAHPYLEQYYDPGDEPVCEE-PFTLEMEFDDLPKEKLKELIWEEAEAHH 358
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 246 bits (628), Expect = 5e-65
Identities = 137/354 (38%), Positives = 214/354 (59%), Gaps = 17/354 (4%)
Query: 67 FSVPGRYEI-LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELK 125
F V +Y+ + +GKG+YG V SA++ + T+E +AIKK+ + F +I KR +RE+K
Sbjct: 56 FEVTAKYKPPIMPIGKGAYGIVCSAMN--SETNE-SVAIKKIANAFDNKIDAKRTLREIK 112
Query: 126 FMSYFKGHRNIVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + H NIV++ D+ ++ +Y EL+D DL ++I SN SE H ++FLY
Sbjct: 113 LLRHMD-HENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLY 171
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
QIL G+KYIHSA+V+HRDLKP N+L + ++KICDFGLAR S S+ +T Y
Sbjct: 172 QILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSE--------SDFMTEY 223
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V TRWYRAPEL+L+ Y+ ++D+W+VGCI E RKP+F G D +HQ+ + +++GTP
Sbjct: 224 VVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 283
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+ + + + P Y + + FP A+DL+E+++ ++P R+TV +
Sbjct: 284 SEEELEFLNENA--KRYIRQLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLD 341
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQ 418
AL HP+L + + EP C PF+F +E H S E+++E + E F+ + Q
Sbjct: 342 ALAHPYLNSLHDISDEPECTI-PFNFDFENHALSEEQMKELIYREALAFNPEYQ 394
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 244 bits (624), Expect = 1e-64
Identities = 127/332 (38%), Positives = 208/332 (62%), Gaps = 15/332 (4%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G+G+YG V S +D T+E+ +A+KK+ + F + KR +RE+K + + H NI++
Sbjct: 44 IGRGAYGIVCSVLD--TETNEL-VAMKKIANAFDNHMDAKRTLREIKLLRHLD-HENIIA 99
Query: 139 LIDLEIVN-EEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSAD 197
+ D+ +S +Y EL+D DL ++I SN SE H ++FLYQ+L G+KYIHSA+
Sbjct: 100 IRDVVPPPLRRQFSDVYISTELMDTDLHQIIRSNQSLSEEHCQYFLYQLLRGLKYIHSAN 159
Query: 198 VIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELIL 257
+IHRDLKP N+L + ++KICDFGLAR S ++ +T YV TRWYRAPEL+L
Sbjct: 160 IIHRDLKPSNLLLNANCDLKICDFGLARPTSE--------NDFMTEYVVTRWYRAPELLL 211
Query: 258 SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRC 317
+ Y+ ++D+W+VGCI E RKP+F G D +HQ+ + ++LGTP + + + +
Sbjct: 212 NSSDYTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDL-GFTHNED 270
Query: 318 YDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNP 377
+ P + + P ++F + + A+DL++R++ ++P R+TVE+AL+H +L ++ +P
Sbjct: 271 AKRYIRQLPNFPRQPLAKLFSHVNPMAIDLVDRMLTFDPNRRITVEQALNHQYLAKLHDP 330
Query: 378 EAEPICPHGPFDFTYEKHLYSMERLRECLCDE 409
EPIC PF F +E+ E+++E + E
Sbjct: 331 NDEPIC-QKPFSFEFEQQPLDEEQIKEMIYQE 361
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 242 bits (618), Expect = 7e-64
Identities = 134/350 (38%), Positives = 217/350 (61%), Gaps = 17/350 (4%)
Query: 67 FSVPGRYEI-LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELK 125
F +P +Y+ ++ +G+G+ G V SAVD + T+E ++AIKK+T +F I KR +RE+K
Sbjct: 53 FELPAKYKPPIRPIGRGACGIVCSAVD--SETNE-KVAIKKITQVFDNTIEAKRTLREIK 109
Query: 126 FMSYFKGHRNIVSLIDLEIVNE-EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ +F H NIV++ D+ + + + + +Y EL+++DL R + S+ ++ H +F+Y
Sbjct: 110 LLRHFD-HENIVAIRDVILPPQRDSFEDVYIVNELMEFDLYRTLKSDQELTKDHGMYFMY 168
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
QIL G+KYIHSA+V+HRDLKP N+L S ++KICDFGLAR A SN +T Y
Sbjct: 169 QILRGLKYIHSANVLHRDLKPSNLLLSTQCDLKICDFGLAR--------ATPESNLMTEY 220
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V TRWYRAPEL+L Y+ ++D+W+VGCI E R+P+F G D ++Q+ + +++GTP
Sbjct: 221 VVTRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTP 280
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+ + + S + P + + E FP A+DL+E+++ ++P+ R++V+E
Sbjct: 281 SEEELGSL--SEYAKRYIRQLPTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKE 338
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
AL HP+L + EP C PF+F ++H +S E+ RE + E F+
Sbjct: 339 ALAHPYLSSFHDITDEPECSE-PFNFDLDEHPFSEEQFRELIYCEALAFN 387
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 241 bits (616), Expect = 1e-63
Identities = 138/349 (39%), Positives = 209/349 (59%), Gaps = 20/349 (5%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F + RY LQ +G G++G V SA D+ + +A+KK+ F+ +L KR RELK
Sbjct: 14 FEITTRYSDLQPIGMGAFGLVCSAKDQ---LTGMNVAVKKIMKPFSTPVLAKRTYRELKL 70
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
+ + + H NI+SL D+ I P+ +Y EL+ DL R++ S L ++F I++FLYQI
Sbjct: 71 LKHLR-HENIISLSDIFI---SPFEDIYFVTELLGTDLHRLLTSRPLETQF-IQYFLYQI 125
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVA 246
L G+K++HSA VIHRDLKP NIL + ++KICDFGLAR P +T YV+
Sbjct: 126 LRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----------MTGYVS 175
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
TR+YRAPE++L+ ++Y+ VD+W+ GCI AE KP+F G D ++Q I ++LGTP
Sbjct: 176 TRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPM 235
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
VI T S F S PQ +K P+ E F A +A+DL+E+++ ++P R++ +AL
Sbjct: 236 EVIETICSKNTLR-FVQSLPQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAADAL 294
Query: 367 DHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHN 415
H +L +P EP+ FD++++ + +E + + EV FHN
Sbjct: 295 AHNYLAPYHDPTDEPVADE-VFDWSFQDNDLPVETWKVMMYSEVLSFHN 342
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 241 bits (615), Expect = 2e-63
Identities = 134/331 (40%), Positives = 204/331 (61%), Gaps = 13/331 (3%)
Query: 53 DPILTKRSIYS-PANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIF 111
+ + T RS ++ NF +P YE++ ++G+G+YG V +A+ K + +++A+KK+ F
Sbjct: 18 ESVATSRSPHTHDLNFELPEEYEMINLIGQGAYGVVCAALHKPSG---LKVAVKKIHP-F 73
Query: 112 TREILLKRAIRELKFMSYFKGHRNIVSLID-LEIVNEEPYSGLYCYQELVDYDLARVIHS 170
+ R +RE+K + +F+ H NI+S++D L + + +Y QEL++ DL RVI S
Sbjct: 74 NHPVFCLRTLREIKLLRHFR-HENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRS 132
Query: 171 NVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPS 230
L S+ H ++F YQIL +K +HSA V+HRDLKP N+L + ++K+ DFGLAR S
Sbjct: 133 QPL-SDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLAR----S 187
Query: 231 FTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDS 290
T GG +T YVATRWYRAPE++LS + YSK++D+W+ GCILAE +P+F G D
Sbjct: 188 TTAQGGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDY 247
Query: 291 LHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMER 350
Q+ I ILGTP S+R + S P K + +FP AS +A+DL+E+
Sbjct: 248 HSQITLILNILGTPTMDDFSRIKSARARK-YIKSLPFTPKVSFKALFPQASPDAIDLLEK 306
Query: 351 LIDWNPEARLTVEEALDHPFLQQVRNPEAEP 381
L+ +NP+ R+T EEAL HP++ + EP
Sbjct: 307 LLTFNPDKRITAEEALKHPYVAAYHDASDEP 337
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 241 bits (614), Expect = 2e-63
Identities = 135/353 (38%), Positives = 225/353 (63%), Gaps = 17/353 (4%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+++ +++ +LG+G+YG V SA K PT E+ +AIKK+ F + + R +RE+K
Sbjct: 7 YNISSDFQLKSLLGEGAYGVVCSATHK--PTGEI-VAIKKIEP-FDKPLFALRTLREIKI 62
Query: 127 MSYFKGHRNIVSLIDLEIVNE-EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ +FK H NI+++ +++ + E ++ +Y QEL+ DL RVI + +L S+ HI++F+YQ
Sbjct: 63 LKHFK-HENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQML-SDDHIQYFIYQ 120
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSF---TVAGGISNHIT 242
L +K +H ++VIHRDLKP N+L + ++K+CDFGLAR I S + G + +T
Sbjct: 121 TLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMT 180
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YVATRWYRAPE++L+ +YS+++D+W+ GCILAE + R+P+F G D HQ++ I I+G
Sbjct: 181 EYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIG 240
Query: 303 TP-KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
TP +R S R + + S P Y P ++FP + + +DL++R++ ++P R+T
Sbjct: 241 TPHSDNDLRCIESPRARE-YIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRIT 299
Query: 362 VEEALDHPFLQQVRN----PEAEPICPHGPFDFTYEKHLYSMERLRECLCDEV 410
+EAL+HP+LQ + PE EPI P F+F + K + + L++ + +E+
Sbjct: 300 AKEALEHPYLQTYHDPNDEPEGEPI-PPSFFEFDHYKEALTTKDLKKLIWNEI 351
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 240 bits (612), Expect = 3e-63
Identities = 129/364 (35%), Positives = 218/364 (59%), Gaps = 23/364 (6%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F +P +Y+++ ++G+G+YGTV SA+ K + +++AIKK+ F++++ + R IRE+K
Sbjct: 7 FDIPSQYKLVDLIGEGAYGTVCSAIHKPSG---IKVAIKKIQP-FSKKLFVTRTIREIKL 62
Query: 127 MSYFKGHRNIVSLID-LEIVNEEPYSGLYCYQELVDYDLARVIHSN----VLFSEFHIKH 181
+ YF H NI+S++D + V+ + + +Y +EL++ DL +VI++ S+ H+++
Sbjct: 63 LRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQY 122
Query: 182 FLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHI 241
F YQIL +K IHSA VIHRD+KP N+L + ++K+CDFGLAR ++ S + +
Sbjct: 123 FTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFM 182
Query: 242 TNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKIL 301
T YVATRWYRAPE++L+ + Y+ ++D+W+ GCILAE KP+F G D HQ+ I ++L
Sbjct: 183 TEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVL 242
Query: 302 GTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYA--SSEAVDLMERLIDWNPEAR 359
GTP S R + + + P PW ++ + + +DL+++++ +NP+ R
Sbjct: 243 GTPSFEDFNQIKSKRAKE-YIANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKR 301
Query: 360 LTVEEALDHPFLQQVRNPEAEPICPHGPFDFTY-----------EKHLYSMERLRECLCD 408
++ EAL HP+L +P EP P D + E+ +E L++ L D
Sbjct: 302 ISAAEALRHPYLAMYHDPSDEPEYPPLNLDDEFWKLDNKIMRPEEEEEVPIEMLKDMLYD 361
Query: 409 EVSK 412
E+ K
Sbjct: 362 ELMK 365
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 236 bits (601), Expect = 7e-62
Identities = 128/340 (37%), Positives = 211/340 (61%), Gaps = 15/340 (4%)
Query: 76 LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRN 135
L+ +G+G+YG V +A + + T E ++AIKK+ + F I KR +RE+K + + H N
Sbjct: 46 LRPIGRGAYGIVCAATN--SETGE-EVAIKKIGNAFDNIIDAKRTLREIKLLKHMD-HEN 101
Query: 136 IVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIH 194
++++ D+ + E ++ +Y EL+D DL ++I SN ++ H + FLYQ+L G+KY+H
Sbjct: 102 VIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRSNQPLTDDHCRFFLYQLLRGLKYVH 161
Query: 195 SADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPE 254
SA+V+HRDLKP N+L + ++K+ DFGLAR S ++ +T YV TRWYRAPE
Sbjct: 162 SANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSE--------TDFMTEYVVTRWYRAPE 213
Query: 255 LILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGS 314
L+L+ Y+ ++D+W+VGCIL E R+P+F G D +HQ+ I +++G+P + S
Sbjct: 214 LLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRS 273
Query: 315 SRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQV 374
+ PQY + + FP S+ AVDL+E+++ ++P R+TV+EAL HP+L +
Sbjct: 274 DNARR-YVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITVDEALCHPYLAPL 332
Query: 375 RNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
+ EP+C PF+F +E+ + E ++E + E KF+
Sbjct: 333 HDINEEPVCVR-PFNFDFEQPTLTEENIKELIYRETVKFN 371
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 234 bits (598), Expect = 1e-61
Identities = 125/353 (35%), Positives = 218/353 (61%), Gaps = 15/353 (4%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F + +Y ++ +G+G+YG V S++++ T+E ++AIKK+ ++F + R +RELK
Sbjct: 26 FEIDTKYVPIKPIGRGAYGVVCSSINR--ETNE-RVAIKKIHNVFENRVDALRTLRELKL 82
Query: 127 MSYFKGHRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ + + H N+++L D+ + N + +Y EL+D DL ++I S+ S+ H K+FL+Q
Sbjct: 83 LRHVR-HENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSSQSLSDDHCKYFLFQ 141
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+KY+HSA+++HRDLKPGN+L + ++KICDFGLAR + G +T YV
Sbjct: 142 LLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLAR-------TSQGNEQFMTEYV 194
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
TRWYRAPEL+L Y S+D+W+VGCI AE GRKP+F G + L+Q+ I ++G+ +
Sbjct: 195 VTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQ 254
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
+ IR + + F S P + T ++P A+ A+DL++R++ ++P R++V +A
Sbjct: 255 ESDIRFIDNPKARR-FIKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDA 313
Query: 366 LDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQ 418
L HP++ + +P + P H P ++++ +RE + +E+ +H + +
Sbjct: 314 LLHPYMAGLFDPGSNPPA-HVPISLDIDENM-EEPVIREMMWNEMLYYHPEAE 364
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 233 bits (595), Expect = 3e-61
Identities = 132/365 (36%), Positives = 220/365 (60%), Gaps = 19/365 (5%)
Query: 57 TKRSIYSP--ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTRE 114
T+R I+ +F + + + +G+GS+ + S+ + E +AI+K+ + F +
Sbjct: 5 TERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTES-NEETHVAIRKIPNAFGNK 63
Query: 115 ILLKRAIRELKFMSYFKGHRNIVSLIDLEIV--NEEPYSGLYCYQELVDYDLARVIHSNV 172
+ KR +RELK + + +GH NIV L D +IV +G+Y Y+EL++ DL+++I S
Sbjct: 64 LSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQ 123
Query: 173 LFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFT 232
+ H + F+YQILC +KYIHSA+V+H DLKP N+L + ++KIC+FGL+ S +
Sbjct: 124 RLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHK 183
Query: 233 VAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLH 292
V G I Y+ + WY+APE++L+++ +K+VD+W+ GCILAE GRKP+F G D +
Sbjct: 184 VNDGF---IKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVD 240
Query: 293 QVMEIQKILGTPKQIVIRTYGSSRCYD-IFSTSKPQYKKTP---WCEIFPYASSEAVDLM 348
+ I +ILGTP + ++ S + Y+ IF Q+ P + I P A+ EA++L+
Sbjct: 241 HLNHILQILGTPPEETLQEIASQKVYNYIF-----QFGNIPGRSFESILPGANPEALELL 295
Query: 349 ERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCD 408
+++++++P+ R+TVE+AL+HP+L + + E C F F +E H+ SM L +
Sbjct: 296 KKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSC-QKTFRFEFE-HIESMAELGNEVIK 353
Query: 409 EVSKF 413
EV F
Sbjct: 354 EVFDF 358
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 233 bits (593), Expect = 6e-61
Identities = 126/354 (35%), Positives = 214/354 (59%), Gaps = 15/354 (4%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F + +Y ++ +G+G+YG V S+V+ + T+E ++AIKK+ +++ I R +RELK
Sbjct: 26 FEIDTKYMPIKPIGRGAYGVVCSSVN--SDTNE-KVAIKKIHNVYENRIDALRTLRELKL 82
Query: 127 MSYFKGHRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ + + H N+++L D+ + +++ + +Y EL+D DL ++I S+ + S H ++FL+Q
Sbjct: 83 LRHLR-HENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQ 141
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+KYIHSA+++HRDLKPGN+L + ++KICDFGLAR + +T YV
Sbjct: 142 LLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTK-------GQFMTEYV 194
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
TRWYRAPEL+L Y S+D+W+VGCI AE GRKP+F G + L+Q+ I ILG+ +
Sbjct: 195 VTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQR 254
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
+ + + + + S P ++P A A+DL+++++ ++P R++V EA
Sbjct: 255 EEDLEFIDNPKA-KRYIRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKRISVSEA 313
Query: 366 LDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQT 419
L HP++ + +P A P P D ++ L E +RE + +E+ +H T
Sbjct: 314 LQHPYMAPLYDPNANPPA-QVPIDLDVDEDLRE-EMIREMMWNEMLHYHPQAST 365
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 232 bits (592), Expect = 7e-61
Identities = 128/355 (36%), Positives = 210/355 (59%), Gaps = 15/355 (4%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F + +Y ++ +G+G+YG V S+V++ + ++AIKK+ ++F I R +RELK
Sbjct: 26 FEIDTKYVPIKPIGRGAYGVVCSSVNRES---NERVAIKKIHNVFENRIDALRTLRELKL 82
Query: 127 MSYFKGHRNIVSLIDLEIVNEE-PYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ + + H N+V+L D+ + N + + +Y EL+D DL ++I S+ + S H ++FL+Q
Sbjct: 83 LRHLR-HENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQ 141
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+KYIHSA+++HRDLKPGN+L + ++KICDFGLAR + +T YV
Sbjct: 142 LLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLAR-------TSNTKGQFMTEYV 194
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
TRWYRAPEL+L Y S+D+W+VGCI AE GRKPVF G + L+Q+ I ILG+ +
Sbjct: 195 VTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQR 254
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
+ + + + + S P + ++P A+ A+DL+++++ +P R++V EA
Sbjct: 255 EEDLEFIDNPKA-KRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEA 313
Query: 366 LDHPFLQQVRNPEAEPICPHGPFDFTY-EKHLYSMERLRECLCDEVSKFHNDRQT 419
L HP++ + +P A P P D E E +RE + E+ +H + T
Sbjct: 314 LQHPYMAPLYDPSANPPA-QVPIDLDVDEDEDLGAEMIRELMWKEMIHYHPEAAT 367
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 230 bits (587), Expect = 3e-60
Identities = 120/316 (37%), Positives = 200/316 (62%), Gaps = 16/316 (5%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F + +Y ++ +G+G+YG V S+++ + T+E ++AIKK+ ++F I R +RELK
Sbjct: 26 FEIDTKYVPIKPIGRGAYGVVCSSIN--SETNE-RVAIKKIHNVFENRIDALRTLRELKL 82
Query: 127 MSYFKGHRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
+ + + H N++SL D+ + + + +Y EL+D DL ++I S+ S+ H K+FL+Q
Sbjct: 83 LRHVR-HENVISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIKSSQSLSDDHCKYFLFQ 141
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+KY+HSA+++HRDLKPGN+L + ++KICDFGLAR +T YV
Sbjct: 142 LLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLAR----------TYEQFMTEYV 191
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
TRWYRAPEL+L Y S+D+W+VGCI AE GRKP+F G + L+Q+ I ++G+ +
Sbjct: 192 VTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQ 251
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
++ + + F S P K T + I+P+A+ A+DL++R++ ++P R++V +A
Sbjct: 252 DWDLQFIDNQKARR-FIKSLPFSKGTHFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDA 310
Query: 366 LDHPFLQQVRNPEAEP 381
L HP+++ + PE P
Sbjct: 311 LLHPYMEGLLEPECNP 326
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 230 bits (586), Expect = 4e-60
Identities = 134/354 (37%), Positives = 203/354 (56%), Gaps = 27/354 (7%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ +P Y+ LQ +G G+YG V AV +G H +AIKK+ F + KR REL+
Sbjct: 19 WEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMH---VAIKKLARPFQSAVHAKRTYRELRL 75
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSG-------LYCYQELVDYDLARVIHSNVLFSEFHI 179
+ + H N++ L+D I + P +G +Y L+D DL +I L S+ H+
Sbjct: 76 LKHMD-HENVIGLLD--IFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHL-SDDHV 131
Query: 180 KHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISN 239
+ +YQIL G+KYIHSA VIHRDLKP NI + E++I DFGLAR N
Sbjct: 132 QFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTE----------N 181
Query: 240 HITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQK 299
+T YVATRWYRAPE++L+ Y ++VD+W+VGCI+AE R+ +F G D +HQ+ I +
Sbjct: 182 EMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIME 241
Query: 300 ILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEAR 359
+LGTP ++ SS + S P K + +F A+ A+DL+E++++ + E R
Sbjct: 242 MLGTPPAEFLKKI-SSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKR 300
Query: 360 LTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKF 413
+T EEAL HP+L++ P E P P+D ++E +++ +E + EV+ F
Sbjct: 301 ITAEEALSHPYLEKYAEPSVEQTSP--PYDHSFEDMDLPVDKWKELIYKEVTNF 352
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 228 bits (581), Expect = 1e-59
Identities = 125/341 (36%), Positives = 201/341 (58%), Gaps = 15/341 (4%)
Query: 76 LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRN 135
++ +G+G+YG V A + + T+E ++AIKK+ + F + KR +RE+K +S+ H N
Sbjct: 36 IEPIGRGAYGIVCCATN--SETNE-EVAIKKIANAFDNRVDAKRTLREIKLLSHMD-HDN 91
Query: 136 IVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIH 194
++ + D+ E+ +E + +Y EL+D DL ++I S ++ H ++FLYQIL G+KYIH
Sbjct: 92 VIKIKDIIELPEKERFEDVYIVYELMDTDLHQIIRSTQTLTDDHCQYFLYQILRGLKYIH 151
Query: 195 SADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPE 254
SA+V+HRDLKP N++ + ++KICDFGLAR + +T YV TRWYRAPE
Sbjct: 152 SANVLHRDLKPSNLVLNTNCDLKICDFGLAR--------TSNETEIMTEYVVTRWYRAPE 203
Query: 255 LILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGS 314
L+L+ Y+ ++D+W+VGCI E R+ +F G D + Q+ I ++LG+P + S
Sbjct: 204 LLLNSSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSDLDFLRS 263
Query: 315 SRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQV 374
+ P +K + E FP S A+DL E+++ ++P R+TV+EAL P+L +
Sbjct: 264 DNARK-YVKQLPHVQKQSFREKFPNISPMALDLAEKMLVFDPSKRITVDEALKQPYLASL 322
Query: 375 RNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHN 415
EP CP PF F +E+ + ++E + E F N
Sbjct: 323 HEINEEPTCP-TPFSFDFEETALDEQDIKELVWRESLHFKN 362
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 227 bits (578), Expect = 3e-59
Identities = 132/348 (37%), Positives = 195/348 (55%), Gaps = 20/348 (5%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F + RY L +G G++G V SA D +AIKK+ F+ +L KR RELK
Sbjct: 17 FEITNRYNDLNPVGMGAFGLVCSATDT---LTSQPVAIKKIMKPFSTAVLAKRTYRELKL 73
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
+ + + H N++ L D+ + P +Y EL DL R++ + L +F +++FLYQI
Sbjct: 74 LKHLR-HENLICLQDIFL---SPLEDIYFVTELQGTDLHRLLQTRPLEKQF-VQYFLYQI 128
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVA 246
L G+KY+HSA VIHRDLKP NIL + ++KICDFGLAR P +T YV+
Sbjct: 129 LRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQ----------MTGYVS 178
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
TR+YRAPE++L+ ++Y VD+W+ GCI AE KP+F G D +HQ I +LG+P +
Sbjct: 179 TRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPK 238
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
VI T S F TS P P+ E F +AVDL+E+++ ++P+ R+T +AL
Sbjct: 239 DVINTICSENTLK-FVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADAL 297
Query: 367 DHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
HP+ +P EP+ FD+ + ++ R + E+ FH
Sbjct: 298 AHPYSAPYHDPTDEPVA-DAKFDWHFNDADLPVDTWRVMMYSEILDFH 344
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 226 bits (577), Expect = 4e-59
Identities = 127/350 (36%), Positives = 211/350 (60%), Gaps = 19/350 (5%)
Query: 67 FSVPGRY-EILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELK 125
F V +Y ++ +G+G+ S + + THE ++AIKK+ F ++ KR +RE+K
Sbjct: 36 FEVSNKYVPPIRPIGRGA-----SVLSVDSETHE-EIAIKKIGKAFDNKVDAKRTLREIK 89
Query: 126 FMSYFKGHRNIVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + + H N+V + D+ +E + +Y EL+D DL ++I SN ++ H ++FLY
Sbjct: 90 LLRHLE-HENVVVIKDIIRPPKKEDFVDVYIVFELMDTDLHQIIRSNQSLNDDHCQYFLY 148
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
QIL G+KYIHSA+V+HRDLKP N+L + ++KI DFGLAR S + ++T Y
Sbjct: 149 QILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTTSE--------TEYMTEY 200
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V TRWYRAPEL+L+ Y+ ++D+W+VGCI AE R+P+F G D +HQ+ I +++G+P
Sbjct: 201 VVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSP 260
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+ S+ + P++ + + FP +S A+DL+E+++ ++P R+TVEE
Sbjct: 261 DGASLEFLRSANARK-YVKELPKFPRQNFSARFPSMNSTAIDLLEKMLVFDPVKRITVEE 319
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
AL +P+L + + EP+C + F F +E + E ++E + E KF+
Sbjct: 320 ALCYPYLSALHDLNDEPVCSN-HFSFHFEDPSSTEEEIKELVWLESVKFN 368
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 221 bits (564), Expect = 1e-57
Identities = 118/310 (38%), Positives = 181/310 (58%), Gaps = 11/310 (3%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G G+YG V A+D N + Q+AIKK+ FT L KR++RE++ + H NI++
Sbjct: 63 VGAGAYGVVCKAMDTRN---KKQVAIKKIPRAFTAHTLAKRSLREVRILRELL-HENIIA 118
Query: 139 LIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSADV 198
++D+ +Y +L++ DL +++HS E H ++F YQ+L G+KY+HSA +
Sbjct: 119 VLDMFTAEGAHGKDIYLVMDLMETDLHQILHSRQTLMEQHFQYFFYQLLRGLKYLHSAGI 178
Query: 199 IHRDLKPGNILCSITGEIKICDFGLARGISPSFTVA--GGISNHITNYVATRWYRAPELI 256
IHRDLKP N+L + ++I DFG+AR + + TV + H+T YV+TRWYRAPE++
Sbjct: 179 IHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVSTRWYRAPEIL 238
Query: 257 LSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSR 316
S Y VD+W+ GCI AE R+ +F G DS+ Q+ I LG+P++ VI S
Sbjct: 239 FSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEEEVINRITSDL 298
Query: 317 CYDIFSTSKPQYKKT--PWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQV 374
D +KT P+ IFP AS EA +++ L+ +P R + ++ L HPF+ Q
Sbjct: 299 VRDSIEACG---RKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQILQHPFMAQY 355
Query: 375 RNPEAEPICP 384
N + EP+CP
Sbjct: 356 HNDQYEPLCP 365
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 218 bits (556), Expect = 1e-56
Identities = 119/342 (34%), Positives = 199/342 (57%), Gaps = 15/342 (4%)
Query: 76 LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRN 135
++ +G+G+ G V +AV N ++AIKK+ + F I KR +RE+K + + H N
Sbjct: 78 IRPIGRGACGIVCAAV---NSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLRHMD-HEN 133
Query: 136 IVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIH 194
++++ D+ + ++ +Y EL+D DL R++ SN + + +YQ+L G+KY+H
Sbjct: 134 VITIKDIVRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSDQCRFLVYQLLRGLKYVH 193
Query: 195 SADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPE 254
SA+++HRDL+P N+L + E+KI DFGLAR S ++ +T YV TRWYRAPE
Sbjct: 194 SANILHRDLRPSNVLLNSKNELKIGDFGLARTTSD--------TDFMTEYVVTRWYRAPE 245
Query: 255 LILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGS 314
L+L+ Y+ ++D+W+VGCIL E +P+F G D +HQ+ I +++G+P + S
Sbjct: 246 LLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSSLGFLRS 305
Query: 315 SRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQV 374
+ P+Y K + FP + A+DL+ER++ ++P R++V+EAL H +L
Sbjct: 306 DNARR-YVRQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRISVDEALGHAYLSPH 364
Query: 375 RNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHND 416
+ EP+C PF F +E + E ++E + E KF+ D
Sbjct: 365 HDVAKEPVC-STPFSFDFEHPSCTEEHIKELIYKESVKFNPD 405
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 217 bits (553), Expect = 2e-56
Identities = 126/349 (36%), Positives = 200/349 (57%), Gaps = 20/349 (5%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ +P Y +G G+YG+V SA+DK + ++AIKK++ F EI KRA REL
Sbjct: 19 WELPKTYVSPTHVGSGAYGSVCSAIDKRSGE---KVAIKKLSRPFQSEIFAKRAYRELLL 75
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + + H N++ L+D+ + + Y + DL +++ + FSE I++ +Y
Sbjct: 76 LKHMQ-HENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM--GMEFSEEKIQYLVY 132
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q+L G+KYIHSA V+HRDLKPGN+ + E+KI DFGLAR +T Y
Sbjct: 133 QMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAE----------MTGY 182
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V TRWYRAPE+ILS Y+++VD+W+VGCI+AE K +F G D L Q+ +I K+ G P
Sbjct: 183 VVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVP 242
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
++ + + + S PQ + + ++FP AS +A DL+E++++ + + RLT +
Sbjct: 243 GTEFVQKL-NDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQ 301
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKF 413
AL HPF + R+PE E PFD + E +++ ++ + E+ F
Sbjct: 302 ALTHPFFEPFRDPEEETEAQQ-PFDDSLEHEKLTVDEWKQHIYKEIVNF 349
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 217 bits (553), Expect = 2e-56
Identities = 107/259 (41%), Positives = 164/259 (63%), Gaps = 5/259 (1%)
Query: 160 VDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKIC 219
++ DL ++IHS+ + H+++FLYQ+L G+KY+HSA VIHRDLKP N+L + E+KI
Sbjct: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
Query: 220 DFGLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFY 279
DFG+ARG+ S +T YVATRWYRAPEL+LS Y++++D+W+VGCI E
Sbjct: 61 DFGMARGLCTS---PAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 117
Query: 280 GRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPY 339
R+ +F G + +HQ+ I +LGTP VI+ G+ R + S P + PW ++P
Sbjct: 118 ARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAER-VRAYIQSLPPRQPVPWETVYPG 176
Query: 340 ASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSM 399
A +A+ L+ R++ + P AR++ AL HPFL + +P+ EP C PFDF +++ +
Sbjct: 177 ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA-PPFDFAFDREALTR 235
Query: 400 ERLRECLCDEVSKFHNDRQ 418
ER++E + E+ FH R+
Sbjct: 236 ERIKEAIVAEIEDFHARRE 254
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 217 bits (553), Expect = 2e-56
Identities = 124/352 (35%), Positives = 205/352 (58%), Gaps = 23/352 (6%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ +P Y+ LQ +G+G+YG V AV +G T ++AIKK+ F + KR REL+
Sbjct: 18 WEIPETYQNLQPVGQGAYGQVCKAVVRGTST---KVAIKKLARPFQSAVHAKRTYRELRL 74
Query: 127 MSYFKGHRNIVSLIDLEIVNE-----EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKH 181
+ + H N++ L+D+ + + + +Y L+D DL +I + L S+ H++
Sbjct: 75 LKHMD-HENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKL-SDDHVQF 132
Query: 182 FLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHI 241
+YQIL G+KYIHSA VIHRDLKP NI + E++I DFGLAR + +
Sbjct: 133 LVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAE----------SEM 182
Query: 242 TNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKIL 301
T YVATRWYRAPE++L+ Y+++ D+W+VGCI+AE + +F G D +HQ+ I ++L
Sbjct: 183 TGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVL 242
Query: 302 GTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
GTP + S + + S P + + +IF A+ A+DL+E++++ + + R+T
Sbjct: 243 GTPADEFMSRISSESARN-YIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRIT 301
Query: 362 VEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKF 413
E+AL HP++++ +P E +D ++E++ +E+ RE + EV+ F
Sbjct: 302 AEQALAHPYMEKYHDPTDEQTA--ALYDQSFEENELPVEKWREMVFSEVTAF 351
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 216 bits (549), Expect = 7e-56
Identities = 128/363 (35%), Positives = 205/363 (56%), Gaps = 29/363 (7%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ VP RY+ L +G G+YG+V +A D +++A+KK++ F I KR REL+
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTG---LRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + K H N++ L+D+ + E ++ +Y L+ DL ++ L + H++ +Y
Sbjct: 75 LKHMK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD-HVQFLIY 132
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
QIL G+KYIHSAD+IHRDLKP N+ + E+KI DFGLAR + +T Y
Sbjct: 133 QILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD----------DEMTGY 182
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYRAPE++L+ Y+++VD+W+VGCI+AE + +F G D ++Q+ +I ++ GTP
Sbjct: 183 VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTP 242
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+I S + + S Q K + +F A+ AVDL+E+++ + + R+T +
Sbjct: 243 PAYLINRMPSHEARN-YIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQ 301
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFVS 424
AL H + Q +P+ EP+ P+D ++E R+ L DE D + FV
Sbjct: 302 ALAHAYFAQYHDPDDEPVA--DPYDQSFES--------RDLLIDEWKSLTYD-EVISFVP 350
Query: 425 PPL 427
PPL
Sbjct: 351 PPL 353
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 215 bits (548), Expect = 9e-56
Identities = 142/413 (34%), Positives = 233/413 (56%), Gaps = 16/413 (3%)
Query: 6 ISNQSNWNARQMPNVSRATKKLKKLLDPYVDHMKQSY-ELDQNNHIYVDPILTKRSIYSP 64
I N S++++ PN S + +L +++ +D + + + NH+ +DP + +
Sbjct: 39 IFNSSSFSSSSNPNHSANSGEL--IIEEDLDFSGLTLINVPKRNHLPMDPHKKGETEFF- 95
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ RY+I +V+GKGSYG V SAVD + T E ++AIKK+ +F R +RE+
Sbjct: 96 TEYGEANRYQIQEVVGKGSYGVVASAVD--SHTGE-RVAIKKINDVFEHVSDATRILREI 152
Query: 125 KFMSYFKGHRNIVSLIDLEIV-NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFL 183
K + + H ++V + + + + + +Y EL++ DL +VI +N + H + FL
Sbjct: 153 KLLRLLR-HPDVVEIKHIMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFL 211
Query: 184 YQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITN 243
YQ+L G+KY+H+A+V HRDLKP NIL + ++KICDFGLAR SF A + T+
Sbjct: 212 YQLLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLAR---VSFNDA-PTAIFWTD 267
Query: 244 YVATRWYRAPELILS-HKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YVATRWYRAPEL S +Y+ ++D+W+VGCI AE KP+F G + +HQ+ + LG
Sbjct: 268 YVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLG 327
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
TP I + + S+ + + + P+ FP A A+ L+ERL+ ++P+ R +
Sbjct: 328 TPPPESISRIRNEKARRYLSSMRKK-QPVPFSHKFPKADPLALRLLERLLAFDPKDRASA 386
Query: 363 EEALDHPFLQQVRNPEAEPIC-PHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
E+AL P+ + N E EP P +F +E+ + +RE + E+ ++H
Sbjct: 387 EDALADPYFSGLSNSEREPTTQPISKLEFDFERKKLVKDDVRELIYREILEYH 439
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 214 bits (544), Expect = 3e-55
Identities = 147/420 (35%), Positives = 233/420 (55%), Gaps = 32/420 (7%)
Query: 7 SNQSNWNARQMPNVSRAT--KKLKKLLDPYVDHMKQSYELDQNNHIYVDPILTKRSIYSP 64
S+ ++ + P VS + LKKL DP + ++ Q NH+ ++ K+ I +
Sbjct: 26 SSNNHDQIQNPPTVSNPNDDEDLKKLTDP---SKLRQIKVQQRNHLPME----KKGIPNA 78
Query: 65 ANFSVPG---RYEILQVLGKGSYGTVVSAVDKGNPTHEVQ-LAIKKVTSIFTREILLKRA 120
F+ G RY+I +V+GKGSYG V SA+D TH + +AIKK+ +F R
Sbjct: 79 EFFTEYGEANRYQIQEVVGKGSYGVVGSAID----THTGERVAIKKINDVFDHISDATRI 134
Query: 121 IRELKFMSYFKGHRNIVSLIDLEIV-NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHI 179
+RE+K + H ++V + + + + + +Y EL++ DL +VI +N + H
Sbjct: 135 LREIKLLRLLL-HPDVVEIKHIMLPPSRREFRDVYVVFELMESDLHQVIKANDDLTPEHH 193
Query: 180 KHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISN 239
+ FLYQ+L G+KY+H+A+V HRDLKP NIL + ++KICDFGLAR SF A +
Sbjct: 194 QFFLYQLLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLAR---VSFNDA-PTAI 249
Query: 240 HITNYVATRWYRAPELILS-HKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQ 298
T+YVATRWYRAPEL S +Y+ ++D+W+VGCI AE KP+F G + +HQ+ +
Sbjct: 250 FWTDYVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMT 309
Query: 299 KILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEA 358
LGTP I + + + + + P+ + FP A A+ L+ERLI ++P+
Sbjct: 310 DFLGTPPPEAISKIRNDKARRYLGNMRKK-QPVPFSKKFPKADPSALRLLERLIAFDPKD 368
Query: 359 RLTVEEALDHPFL----QQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
R + EEAL P+ +VR P +PI +F +E+ + + +RE + E+ ++H
Sbjct: 369 RPSAEEALADPYFNGLSSKVREPSTQPI---SKLEFEFERKKLTKDDIRELIYREILEYH 425
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 212 bits (540), Expect = 8e-55
Identities = 127/363 (34%), Positives = 205/363 (55%), Gaps = 29/363 (7%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ VP RY+ L +G G+YG+V +A D +++A+KK++ F I KR REL+
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTG---LRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + K H N++ L+D+ + E ++ +Y L+ DL ++ L + H++ +Y
Sbjct: 75 LKHMK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD-HVQFLIY 132
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
QIL G+KYIHSAD+IHRDLKP N+ + E+KI DFGLAR + +T Y
Sbjct: 133 QILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD----------DEMTGY 182
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYRAPE++L+ Y+++VD+W+VGCI+AE + +F G D + Q+ I +++GTP
Sbjct: 183 VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+++ S + + S Q K + +F A+ AVDL+E+++ + + R+T +
Sbjct: 243 GAELLKKISSESARN-YIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQ 301
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFVS 424
AL H + Q +P+ EP+ P+D ++E R+ L DE D + FV
Sbjct: 302 ALAHAYFAQYHDPDDEPVA--DPYDQSFES--------RDLLIDEWKSLTYD-EVISFVP 350
Query: 425 PPL 427
PPL
Sbjct: 351 PPL 353
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 211 bits (538), Expect = 1e-54
Identities = 129/353 (36%), Positives = 209/353 (58%), Gaps = 12/353 (3%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+++ R+++ +V+GKGSYG V SA+D T E ++AIKK+ IF R +RE+
Sbjct: 5 SDYGDANRFKVQEVIGKGSYGVVCSAID--TLTGE-KVAIKKIHDIFEHISDAARILREI 61
Query: 125 KFMSYFKGHRNIVSLIDLEIV-NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFL 183
K + + H +IV + + + + + +Y EL++ DL +VI +N + H + FL
Sbjct: 62 KLLRLLR-HPDIVEIKHIMLPPSRREFKDIYVVFELMESDLHQVIKANDDLTREHYQFFL 120
Query: 184 YQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITN 243
YQ+L +KYIH+A+V HRDLKP NIL + ++KICDFGLAR ++ + T + T+
Sbjct: 121 YQLLRALKYIHTANVYHRDLKPKNILANANCKLKICDFGLAR-VAFNDTPT---TIFWTD 176
Query: 244 YVATRWYRAPELILS-HKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YVATRWYRAPEL S + +Y+ ++D+W++GCI AE KP+F G + +HQ+ + +LG
Sbjct: 177 YVATRWYRAPELCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLG 236
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
TP I + + + TS + P+ + FP A ++ L+ERL+ ++P+ R T
Sbjct: 237 TPSLDTISRVRNEKARR-YLTSMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTA 295
Query: 363 EEALDHPFLQQVRNPEAEPIC-PHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
EEAL P+ + + E EP C P +F +E+ + E +RE + E+ ++H
Sbjct: 296 EEALADPYFKGLAKVEREPSCQPITKMEFEFERRKVTKEDIRELISREILEYH 348
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 211 bits (537), Expect = 2e-54
Identities = 131/371 (35%), Positives = 213/371 (57%), Gaps = 22/371 (5%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RY IL+V+GKGSYG V +A+D T E ++AIKK+ +F R +RE+K + +
Sbjct: 12 RYRILEVIGKGSYGVVCAAID--TQTGE-KVAIKKINDVFEHVSDALRILREVKLLRLLR 68
Query: 132 GHRNIVSLIDLEIV-NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGM 190
H +IV + + + ++ + +Y EL++ DL +VI +N + H + FLYQ+L +
Sbjct: 69 -HPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRAL 127
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
KY+H+A+V HRDLKP NIL + ++K+CDFGLAR +S + T + T+YVATRWY
Sbjct: 128 KYMHTANVYHRDLKPKNILANANCKLKVCDFGLAR-VSFNDTPT---TVFWTDYVATRWY 183
Query: 251 RAPELILSH-KRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
RAPEL S +Y+ ++D+W++GCI AE KP+F G +HQ+ I +LGTPK I
Sbjct: 184 RAPELCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETI 243
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ + + + + P+ + FP A A+ L++RL+ ++P+ R T EAL P
Sbjct: 244 AGVRNEKARKYLNEMRKK-NLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEALADP 302
Query: 370 FLQQVRNPEAEPIC-PHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFVSPPLM 428
+ + + E EP C P +F +E+ + + +RE + E+ ++H P L+
Sbjct: 303 YFKCLAKVEREPSCQPISKMEFEFERRRLTKDDIRELIYREILEYH----------PQLL 352
Query: 429 TPHFIAESNSY 439
+ +E +S+
Sbjct: 353 KDYMNSEGSSF 363
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 210 bits (534), Expect = 4e-54
Identities = 133/375 (35%), Positives = 212/375 (56%), Gaps = 19/375 (5%)
Query: 44 LDQNNHIYVDPILTKRSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQ-L 102
+ + N+I +DP + Y A+ RY+I +V+GKGSYG V SA+D TH + +
Sbjct: 102 VSRRNYILMDPHKKFFTEYGEAS-----RYQIQEVIGKGSYGVVASAID----THSGEKV 152
Query: 103 AIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVSLIDLEIV-NEEPYSGLYCYQELVD 161
AIKK+ +F R +RE+K + + H +IV + + + + + +Y EL++
Sbjct: 153 AIKKINDVFEHVSDATRILREIKLLRLLR-HPDIVEIKHVMLPPSRREFRDIYVVFELME 211
Query: 162 YDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDF 221
DL +VI +N + H + FLYQ+L G+K+IH+A+V HRDLKP NIL + ++KICDF
Sbjct: 212 SDLHQVIKANDDLTPEHYQFFLYQLLRGLKFIHTANVFHRDLKPKNILANSDCKLKICDF 271
Query: 222 GLARGISPSFTVAGGISNHITNYVATRWYRAPELILS-HKRYSKSVDMWAVGCILAEFYG 280
GLAR SF A + T+YVATRWYRAPEL S +Y+ ++D+W++GCI AE
Sbjct: 272 GLAR---VSFNDAPS-AIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAEMLT 327
Query: 281 RKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYA 340
KP+F G + +HQ+ + +LGTP I + + + + P+ FP+
Sbjct: 328 GKPLFPGKNVVHQLDIMTDLLGTPPPEAIARIRNEKARRYLGNMR-RKPPVPFTHKFPHV 386
Query: 341 SSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPIC-PHGPFDFTYEKHLYSM 399
A+ L+ RL+ ++P+ R + EEAL P+ + N + EP P +F +E+ +
Sbjct: 387 DPLALRLLHRLLAFDPKDRPSAEEALADPYFYGLANVDREPSTQPIPKLEFEFERRKITK 446
Query: 400 ERLRECLCDEVSKFH 414
E +RE + E+ ++H
Sbjct: 447 EDVRELIYREILEYH 461
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 206 bits (525), Expect = 4e-53
Identities = 124/348 (35%), Positives = 195/348 (55%), Gaps = 20/348 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y LQ +G G+YG V SAVD ++AIKK+ F E+ KRA REL+ + + +
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGA---KVAIKKLYRPFQSELFAKRAYRELRLLKHMR- 82
Query: 133 HRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGM 190
H N++ L+D+ +E + ++ Y + DL +++ L E I+ +YQ+L G+
Sbjct: 83 HENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKL-GEDRIQFLVYQMLKGL 141
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
+YIH+A +IHRDLKPGN+ + E+KI DFGLAR + +T YV TRWY
Sbjct: 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQAD----------SEMTGYVVTRWY 191
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
RAPE+IL+ RY+++VD+W+VGCI+AE K +F G+D L Q+ EI K+ GTP ++
Sbjct: 192 RAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQ 251
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
S + P+ +K + I AS AV+L+E+++ + E R+T EAL HP+
Sbjct: 252 RLQSDEAKNNMK-GLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPY 310
Query: 371 LQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQ 418
+ + + E EP +D +++ +++ + EV F RQ
Sbjct: 311 FESLHDTEDEPQVQ--KYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQ 356
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 204 bits (520), Expect = 2e-52
Identities = 122/349 (34%), Positives = 193/349 (54%), Gaps = 20/349 (5%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ VP R + L+ +G G+YG+V SA D ++A+KK++ F I +R REL+
Sbjct: 18 WEVPQRLQGLRPVGSGAYGSVCSAYDA---RLRQKVAVKKLSRPFQSLIHARRTYRELRL 74
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + K H N++ L+D+ + E +S +Y L+ DL ++ L E H++ +Y
Sbjct: 75 LKHLK-HENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDE-HVQFLVY 132
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q+L G+KYIHSA +IHRDLKP N+ + E++I DFGLAR +T Y
Sbjct: 133 QLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD----------EEMTGY 182
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYRAPE++L+ Y+++VD+W+VGCI+AE K +F G+D + Q+ I +++GTP
Sbjct: 183 VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTP 242
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
V+ S + P +K IF A+ A+DL+ R++ + + R++ E
Sbjct: 243 SPEVLAKISSEHARTYIQSLPPMPQK-DLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAE 301
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKF 413
AL H + Q +PE EP P+D + E ++E +E EV F
Sbjct: 302 ALAHAYFSQYHDPEDEPEAE--PYDESVEAKERTLEEWKELTYQEVLSF 348
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 204 bits (520), Expect = 2e-52
Identities = 128/347 (36%), Positives = 196/347 (55%), Gaps = 14/347 (4%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQ-LAIKKVTSIFTREILLKRAIRELKFMSYF 130
RY I +V+GKGSYG V SA D TH + +AIKK+ IF R +RE+K +
Sbjct: 24 RYRIEEVIGKGSYGVVCSAYD----THTGEKVAIKKINDIFEHVSDATRILREIKLLRLL 79
Query: 131 KGHRNIVSLIDLEIV-NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCG 189
+ H +IV + + + + + +Y EL++ DL +VI +N + H + FLYQ+L G
Sbjct: 80 R-HPDIVEIKHILLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRG 138
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+KYIH+A+V HRDLKP NIL + ++KICDFGLAR A T+YVATRW
Sbjct: 139 LKYIHTANVFHRDLKPKNILANADCKLKICDFGLARVAFNDTPTA----IFWTDYVATRW 194
Query: 250 YRAPELILS-HKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
YRAPEL S +Y+ ++D+W++GCI AE KP+F G + +HQ+ + +LGTP
Sbjct: 195 YRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEA 254
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
I + + S+ + + K P+ FP+ A+ L+E+++ + P+ R T EEAL
Sbjct: 255 IGRVRNEKARRYLSSMRKK-KPIPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEALAD 313
Query: 369 PFLQQVRNPEAEPIC-PHGPFDFTYEKHLYSMERLRECLCDEVSKFH 414
+ + + E EP P +F +E+ + E +RE + E ++H
Sbjct: 314 VYFKGLAKVEREPSAQPVTKLEFEFERRRITKEDVRELIYRESLEYH 360
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 203 bits (516), Expect = 5e-52
Identities = 112/305 (36%), Positives = 175/305 (56%), Gaps = 10/305 (3%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+Y + LG G++G V A+D Q+AIKK+T +F + K A+RE++
Sbjct: 43 QYLAQENLGAGAFGVVCRAIDS---KLNKQVAIKKITRVFKNQSTAKCALREIRITRELS 99
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMK 191
H NI++ D+ + +Y +L++ DL V+ SN +E H ++F YQIL G+K
Sbjct: 100 -HENIINSTDVLMRESGSGQDIYIVMDLMETDLLSVLKSNQTLNEKHFQYFFYQILKGLK 158
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARG-----ISPSFTVAGGISNHITNYVA 246
Y+HSA +IHRDLKP N+L + +KI DFG++R +P+ + IS ++ YV+
Sbjct: 159 YLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQYVS 218
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
T WYRAPE++LS Y VD+W+ GCILAE +P+F G DS Q+ + + LGTP +
Sbjct: 219 TLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTPDE 278
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
VIR S D S+ P+ P+ +FP AS EA +++ +++ +P R + E+ L
Sbjct: 279 QVIRRIKSPSIRDYISSFGPK-TPLPFTAMFPNASIEARNIVSKMLQISPWKRFSAEQLL 337
Query: 367 DHPFL 371
+ PF+
Sbjct: 338 EEPFV 342
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 202 bits (513), Expect = 1e-51
Identities = 121/350 (34%), Positives = 195/350 (55%), Gaps = 20/350 (5%)
Query: 69 VPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMS 128
VP Y L +G G+YGTV +A + T ++AIKK F I +R REL+ +
Sbjct: 31 VPNYYINLTPIGTGAYGTVCAAECTRSGT---RVAIKKFNRPFQSIIHARRTYRELRLLR 87
Query: 129 YFKGHRNIVSLIDLEIVNEE--PYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
H NI+ L+D+ NE +Y L+ DL+ ++ L ++ HI+ +YQI
Sbjct: 88 CMC-HENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRL-NDDHIQFLVYQI 145
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVA 246
L G+KYIHSAD+IHRDLKP NI + E+KI DFGLAR + +T YVA
Sbjct: 146 LRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTD----------SEMTGYVA 195
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
TRWYRAPE++L+ Y+++VD+W+VGCILAE K +F G+D + Q+ I + GTP +
Sbjct: 196 TRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDE 255
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
++ S + + + P+ + + +F A+ +A+DL+E+++ +P+ R T +EA+
Sbjct: 256 EFLKKISSEEARN-YIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAM 314
Query: 367 DHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHND 416
+H +L + EPI D + +++ ++ + +E+S F +
Sbjct: 315 EHEYLAAYHDETDEPIAEE--MDLNDDVRADTIDEWKKIIWEEISDFQKN 362
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 200 bits (509), Expect = 3e-51
Identities = 106/312 (33%), Positives = 177/312 (55%), Gaps = 7/312 (2%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
++++ + LGKG+YG V A DK + +A+KK+ F +R RE+ F+ F
Sbjct: 12 KFDLQKRLGKGAYGIVWKAYDKRS---RETVALKKIFDAFRNPTDSQRTFREVMFLQEFG 68
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMK 191
H N++ L ++ + + +Y E ++ DL VI + + H ++ + Q+ ++
Sbjct: 69 KHPNVIKLYNIFRADND--RDIYLAFEFMEADLHNVIKKGSILKDVHKQYIMCQLFRAIR 126
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISN-HITNYVATRWY 250
++HS +V+HRDLKP N+L +K+ DFGLAR +S G +T YVATRWY
Sbjct: 127 FLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWY 186
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
R+PE++L+ KRY+K VDMW++GCILAE + +F G+ +++Q+ I + P + I
Sbjct: 187 RSPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIA 246
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
+ GS + PQ + P I + + A+D+++RL+ + P+ RLTVE+ L HP+
Sbjct: 247 SIGSHYAASVLE-KMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHPY 305
Query: 371 LQQVRNPEAEPI 382
+ Q NP EP+
Sbjct: 306 VVQFHNPSEEPV 317
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 199 bits (507), Expect = 5e-51
Identities = 120/349 (34%), Positives = 192/349 (54%), Gaps = 32/349 (9%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G G++G V S D P ++A+KK+ ++F + KR RELK + +FK H N++S
Sbjct: 132 IGYGAFGVVWSVTD---PRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDNVLS 187
Query: 139 LID-LEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSAD 197
+D L+ + + + +Y EL+ DL ++I S S H+K FLYQIL G+KY+HSA
Sbjct: 188 ALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAG 247
Query: 198 VIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELIL 257
++HRD+KPGN+L + +KICDFGLAR S H+T V T++YRAPE+++
Sbjct: 248 ILHRDIKPGNLLVNSNCVLKICDFGLAR------VEELDESRHMTQEVVTQYYRAPEILM 301
Query: 258 SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRC 317
+ YS ++D+W+VGCI AE GR+ +F + Q+ I +LGTP +RT
Sbjct: 302 GSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAK 361
Query: 318 YDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQ---- 373
I Q + A+ EAV L+ R++ ++P R++ ++AL HP+L +
Sbjct: 362 AHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLR 421
Query: 374 ----------------VRNPEAEPICPHGPFDFTYEKHLYSMERLRECL 406
V + EP+ + FD T+EK+L S+ +++E +
Sbjct: 422 YHTCMCKCCFSTSTGRVYTSDFEPV-TNPKFDDTFEKNLSSVRQVKEII 469
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 199 bits (506), Expect = 7e-51
Identities = 127/343 (37%), Positives = 195/343 (56%), Gaps = 12/343 (3%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+Y+I +V+GKGSYG V SA P ++AIKK+T++F R +RE+K + +
Sbjct: 15 QYQIQEVVGKGSYGVVASAEC---PHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLR 71
Query: 132 GHRNIVSLIDLEIVN-EEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGM 190
H +IV + + + + + +Y EL++ DL V+ N + H + FLYQ+L G+
Sbjct: 72 -HPDIVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKVNDDLTPQHHQFFLYQLLRGL 130
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
K++HSA V HRDLKP NIL + +IKICD GLAR SFT + + T+YVATRWY
Sbjct: 131 KFMHSAHVFHRDLKPKNILANADCKIKICDLGLAR---VSFTDSPS-AVFWTDYVATRWY 186
Query: 251 RAPELILS-HKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
RAPEL S + Y+ ++DMW+VGCI AE KP+F G + +HQ+ + +LGTP I +
Sbjct: 187 RAPELCGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPITL 246
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ + + + P+ FP A+ L++RLI ++P+ R + EEAL P
Sbjct: 247 SRIRNEKARKYLGNMR-RKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALADP 305
Query: 370 FLQQVRNPEAEPI-CPHGPFDFTYEKHLYSMERLRECLCDEVS 411
+ Q + N + EP P +F +E+ + + +RE + E S
Sbjct: 306 YFQGLANVDYEPSRQPISKLEFEFERRKLTRDDVRELMYREES 348
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 199 bits (506), Expect = 7e-51
Identities = 127/360 (35%), Positives = 206/360 (56%), Gaps = 21/360 (5%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQ-LAIKKVTSIFTREILLKRAIRELKFMSYF 130
RY IL+V+GKGSYG V +A+D TH + +AIKK+ +F R +RE+K +
Sbjct: 12 RYRILEVIGKGSYGVVCAAID----THTGEKVAIKKINDVFEHISDALRILREVKLLRLL 67
Query: 131 KGHRNIVSLIDLEIV-NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCG 189
+ H +IV + + + ++ + +Y EL++ DL +VI +N + H + FLYQ+L
Sbjct: 68 R-HPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRA 126
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLAR-GISPSFTVAGGISNHITNYVATR 248
+K++H+A+V HRDLKP NIL + ++K+CDFGLAR + + T T+YVATR
Sbjct: 127 LKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTV-----FWTDYVATR 181
Query: 249 WYRAPELILS-HKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
WYRAPEL S +Y+ ++D+W++GCI AE KP+F G +HQ+ I +LGTPK
Sbjct: 182 WYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSE 241
Query: 308 VIRTYGSSRCYDIFSTSKPQYKKTP--WCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
I + + + + KK P + + F A A+ L++RL+ ++P+ R T EA
Sbjct: 242 TISGVRNDKARKYLTEMR---KKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEA 298
Query: 366 LDHPFLQQVRNPEAEPICPH-GPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFVS 424
L P+ + + E EP +F +E+ + + +RE + E+ ++H + KD++S
Sbjct: 299 LADPYFKGLSKIEREPSSQQISKMEFEFERRRLTKDDIRELIYREILEYH-PQLLKDYMS 357
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 194 bits (494), Expect = 2e-49
Identities = 124/369 (33%), Positives = 206/369 (55%), Gaps = 39/369 (10%)
Query: 68 SVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFM 127
+VP + + +G G++G V + D P ++A+KK+ ++F + KR RELK +
Sbjct: 35 AVPQDVQPDRPIGYGAFGVVWAVTD---PRDGRRVALKKLPNVFQSLVSSKRVFRELKML 91
Query: 128 SYFKGHRNIVSLID-LEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
+FK H N++S +D L+ + + + +Y EL+ DL ++I S S HIK FLYQI
Sbjct: 92 CFFK-HENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQI 150
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVA 246
L G+KY+HSA ++HRD+KPGN+L + +KICDFGLAR P + H+T V
Sbjct: 151 LRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPD------QAKHMTQEVV 204
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
T++YRAPE+++ + YS +VD+W+VGCI E GR+ +F + + Q+ I ++LGTP
Sbjct: 205 TQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTM 264
Query: 307 IVIR-TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
+R +R + + KP + + +A+ EAV L+ +++ ++P+ R++V +A
Sbjct: 265 EDMRHACEGARTHMLRRAPKPPSFSVLY-TLSSHATHEAVHLLCQMLVFDPDKRISVTDA 323
Query: 366 LDHPFLQQVR---------------------NPEAEPICPHGPFDFTYEKHLYSMERLRE 404
L HP+L + R + EP PFD +E+ L S+++++E
Sbjct: 324 LAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQ-PFDDLWERKLTSVQQVKE 382
Query: 405 CLCDEVSKF 413
E+ KF
Sbjct: 383 ----EMHKF 387
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 190 bits (483), Expect = 3e-48
Identities = 113/314 (35%), Positives = 178/314 (55%), Gaps = 41/314 (13%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G G++G V S D P ++A+KK+ ++F KR RE+K +S F+ H N++S
Sbjct: 49 IGYGAFGVVWSVTD---PRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFR-HDNVLS 104
Query: 139 LID-LEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSAD 197
L+D L+ N + LY EL+ DL ++I S + H+K F+YQIL G+KY+H+A+
Sbjct: 105 LLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTAN 164
Query: 198 VIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELIL 257
++HRD+KPGN+L + +KICDFGLAR + ++T+ V T++YRAPEL++
Sbjct: 165 ILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRL------NMTHEVVTQYYRAPELLM 218
Query: 258 SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV--------- 308
+RY+ +VD+W+VGCI AE RK +F + Q+ I +LGTP Q
Sbjct: 219 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 278
Query: 309 -------IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
+R + R Y I S + EAVDL+++L+ ++P+ R++
Sbjct: 279 NHVLRAGLRAPDTQRLYKIASPDDKNH--------------EAVDLLQKLLHFDPDKRIS 324
Query: 362 VEEALDHPFLQQVR 375
VEEAL H +L++ R
Sbjct: 325 VEEALQHRYLEEGR 338
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 190 bits (483), Expect = 3e-48
Identities = 113/314 (35%), Positives = 178/314 (55%), Gaps = 41/314 (13%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G G++G V S D P ++A+KK+ ++F KR RE+K +S F+ H N++S
Sbjct: 74 IGYGAFGVVWSVTD---PRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFR-HDNVLS 129
Query: 139 LID-LEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSAD 197
L+D L+ N + LY EL+ DL ++I S + H+K F+YQIL G+KY+H+A+
Sbjct: 130 LLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTAN 189
Query: 198 VIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELIL 257
++HRD+KPGN+L + +KICDFGLAR + ++T+ V T++YRAPEL++
Sbjct: 190 ILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRL------NMTHEVVTQYYRAPELLM 243
Query: 258 SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV--------- 308
+RY+ +VD+W+VGCI AE RK +F + Q+ I +LGTP Q
Sbjct: 244 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 303
Query: 309 -------IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
+R + R Y I S + EAVDL+++L+ ++P+ R++
Sbjct: 304 NHVLRAGLRAPDTQRLYKIASPDDKNH--------------EAVDLLQKLLHFDPDKRIS 349
Query: 362 VEEALDHPFLQQVR 375
VEEAL H +L++ R
Sbjct: 350 VEEALQHRYLEEGR 363
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 190 bits (483), Expect = 3e-48
Identities = 113/314 (35%), Positives = 178/314 (55%), Gaps = 41/314 (13%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G G++G V S D P ++A+KK+ ++F KR RE+K +S F+ H N++S
Sbjct: 246 IGYGAFGVVWSVTD---PRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFR-HDNVLS 301
Query: 139 LID-LEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSAD 197
L+D L+ N + LY EL+ DL ++I S + H+K F+YQIL G+KY+H+A+
Sbjct: 302 LLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTAN 361
Query: 198 VIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELIL 257
++HRD+KPGN+L + +KICDFGLAR + ++T+ V T++YRAPEL++
Sbjct: 362 ILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRL------NMTHEVVTQYYRAPELLM 415
Query: 258 SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV--------- 308
+RY+ +VD+W+VGCI AE RK +F + Q+ I +LGTP Q
Sbjct: 416 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 475
Query: 309 -------IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
+R + R Y I S + EAVDL+++L+ ++P+ R++
Sbjct: 476 NHVLRAGLRAPDTQRLYKIASPDDKNH--------------EAVDLLQKLLHFDPDKRIS 521
Query: 362 VEEALDHPFLQQVR 375
VEEAL H +L++ R
Sbjct: 522 VEEALQHRYLEEGR 535
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 187 bits (476), Expect = 2e-47
Identities = 123/367 (33%), Positives = 198/367 (53%), Gaps = 45/367 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +A+KK++ F + KRA REL
Sbjct: 18 STFTVLKRYQQLKPIGSGAQGIVCAAFDT---VLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
+ H+NI+SL+++ + E + +Y EL+D +L +VIH + + +
Sbjct: 75 VLLKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR +F +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+AE K +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLG 242
Query: 303 TPK-------QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + E+FP +S+
Sbjct: 243 TPSAEFMKKLQPTVRNYVENR---------PKYPGIKFEELFPDWIFPSESERDKIKTSQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P+ R++V+EAL HP++ +P P +D E+ +++E +
Sbjct: 294 ARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWK 353
Query: 404 ECLCDEV 410
E + EV
Sbjct: 354 ELIYKEV 360
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 187 bits (476), Expect = 2e-47
Identities = 123/367 (33%), Positives = 198/367 (53%), Gaps = 45/367 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +A+KK++ F + KRA REL
Sbjct: 18 STFTVLKRYQQLKPIGSGAQGIVCAAFDT---VLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
+ H+NI+SL+++ + E + +Y EL+D +L +VIH + + +
Sbjct: 75 VLLKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR +F +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+AE K +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLG 242
Query: 303 TPK-------QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + E+FP +S+
Sbjct: 243 TPSAEFMKKLQPTVRNYVENR---------PKYPGIKFEELFPDWIFPSESERDKIKTSQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P+ R++V+EAL HP++ +P P +D E+ +++E +
Sbjct: 294 ARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWK 353
Query: 404 ECLCDEV 410
E + EV
Sbjct: 354 ELIYKEV 360
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 187 bits (476), Expect = 2e-47
Identities = 113/344 (32%), Positives = 184/344 (52%), Gaps = 18/344 (5%)
Query: 68 SVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFM 127
+V +++ + +GKG+YG V A D+ +A+KKV F E +R RE+ F+
Sbjct: 20 TVESIFDVRKRMGKGAYGIVWKATDRRTKN---TVALKKVFDAFRDETDAQRTYREVIFL 76
Query: 128 SYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQIL 187
F+ H NIV L+D I Y E ++ DL VI + + H + +YQ++
Sbjct: 77 RAFRCHPNIVRLVD--IFKASNNLDFYLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLI 134
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNH--ITNYV 245
+K+IHS +VIHRDLKP NIL +K+ DFGLAR +S S + + +T+YV
Sbjct: 135 NAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLS-SRRIYDDLEQDGMLTDYV 193
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
ATRWYRAPE++++ + Y+K +DMW +GCIL E +KP+F G +++Q+ +I L
Sbjct: 194 ATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVT 253
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
++ I + G S + S + + ++ E+ + + L++ L+ NP RLT +EA
Sbjct: 254 KLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEA 313
Query: 366 LDHPFLQQVRNPEAE---------PICPHGPFDF-TYEKHLYSM 399
+ HP++ + + AE P+ H +D Y LY +
Sbjct: 314 IRHPYVSRFQYASAEMDLHMDVVPPLKDHVRYDVDQYRNSLYEL 357
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 186 bits (473), Expect = 5e-47
Identities = 125/372 (33%), Positives = 193/372 (51%), Gaps = 36/372 (9%)
Query: 60 SIYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKR 119
S+ + F + RY L+ LG G G V SAVD + ++AIKK+ + T +K
Sbjct: 7 SLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDC---DKRVAIKKI--VLTDPQSVKH 61
Query: 120 AIRELKFMSYFKGHRNIVSLIDL----------EIVNEEPYSGLYCYQELVDYDLARVIH 169
A+RE+K + H NIV + ++ ++ + + +Y QE ++ DLA V+
Sbjct: 62 ALREIKIIRRLD-HDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE 120
Query: 170 SNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEI-KICDFGLARGIS 228
L E H + F+YQ+L G+KYIHSA+V+HRDLKP N+ + + KI DFGLAR +
Sbjct: 121 QGPLLEE-HARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMD 179
Query: 229 PSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGN 288
P ++ G H++ + T+WYR+P L+LS Y+K++DMWA GCI AE K +F G
Sbjct: 180 PHYSHKG----HLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGA 235
Query: 289 DSLHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLM 348
L Q+ I + + + + S ++ + P ++ P S EA+D +
Sbjct: 236 HELEQMQLILESIPVVHEEDRQELLS--VIPVYIRNDMTEPHKPLTQLLPGISREALDFL 293
Query: 349 ERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYE-----------KHLY 397
E+++ ++P RLT EEAL HP++ P EPI H PF E H+Y
Sbjct: 294 EQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSH-PFHIEDEVDDILLMDETHSHIY 352
Query: 398 SMERLRECLCDE 409
+ ER +C E
Sbjct: 353 NWERYHDCQFSE 364
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 185 bits (469), Expect = 1e-46
Identities = 121/367 (32%), Positives = 196/367 (52%), Gaps = 45/367 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +A+KK++ F + KRA REL
Sbjct: 18 STFTVLKRYQQLKPIGSGAQGIVCAAFDT---VLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
+ H+NI+SL+++ + E + +Y EL+D +L +VIH + + +
Sbjct: 75 VLLKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR +F +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLG 242
Query: 303 TPK-------QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + E+FP +S+
Sbjct: 243 TPSAEFMKKLQPTVRNYVENR---------PKYPGIKFEELFPDWIFPSESERDKIKTSQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P+ R++V+EAL HP++ +P P +D E+ +++E +
Sbjct: 294 ARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWK 353
Query: 404 ECLCDEV 410
E + EV
Sbjct: 354 ELIYKEV 360
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 185 bits (469), Expect = 1e-46
Identities = 121/367 (32%), Positives = 196/367 (52%), Gaps = 45/367 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +A+KK++ F + KRA REL
Sbjct: 18 STFTVLKRYQQLKPIGSGAQGIVCAAFDT---VLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
+ H+NI+SL+++ + E + +Y EL+D +L +VIH + + +
Sbjct: 75 VLLKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR +F +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLG 242
Query: 303 TPK-------QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + E+FP +S+
Sbjct: 243 TPSAEFMKKLQPTVRNYVENR---------PKYPGIKFEELFPDWIFPSESERDKIKTSQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P+ R++V+EAL HP++ +P P +D E+ +++E +
Sbjct: 294 ARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWK 353
Query: 404 ECLCDEV 410
E + EV
Sbjct: 354 ELIYKEV 360
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 185 bits (469), Expect = 1e-46
Identities = 121/367 (32%), Positives = 196/367 (52%), Gaps = 45/367 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +A+KK++ F + KRA REL
Sbjct: 18 STFTVLKRYQQLKPIGSGAQGIVCAAFDT---VLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
+ H+NI+SL+++ + E + +Y EL+D +L +VIH + + +
Sbjct: 75 VLLKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR +F +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLG 242
Query: 303 TPK-------QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + E+FP +S+
Sbjct: 243 TPSAEFMKKLQPTVRNYVENR---------PKYPGIKFEELFPDWIFPSESERDKIKTSQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P+ R++V+EAL HP++ +P P +D E+ +++E +
Sbjct: 294 ARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWK 353
Query: 404 ECLCDEV 410
E + EV
Sbjct: 354 ELIYKEV 360
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 183 bits (465), Expect = 4e-46
Identities = 126/338 (37%), Positives = 184/338 (54%), Gaps = 27/338 (7%)
Query: 61 IYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRA 120
I S + + GR+ Q LG G G V+SAVD ++A+KK+ R +K A
Sbjct: 8 IASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACR---KVAVKKIALSDARS--MKHA 62
Query: 121 IRELKFMSYFKGHRNIVSLIDL------EIVNEE-PYSGLYCYQELVDYDLARVIHSNVL 173
+RE+K + H NIV + ++ ++ E +S Y QE ++ DLAR++ L
Sbjct: 63 LREIKIIRRLD-HDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTL 121
Query: 174 FSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEI-KICDFGLARGISPSFT 232
E H K F+YQ+L G+KYIHSA+V+HRDLKP NI S + KI DFGLAR + ++
Sbjct: 122 AEE-HAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS 180
Query: 233 VAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLH 292
G +S + T+WYR+P L+LS Y+K++DMWA GCILAE + +F G H
Sbjct: 181 HKGYLSEGLV----TKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAG---AH 233
Query: 293 QVMEIQKILGTPKQIVIRTYGSSRCYDIFST--SKPQYKKTPWCEIFPYASSEAVDLMER 350
++ ++Q IL T VIR + + S K P ++ P +SEA+D +E+
Sbjct: 234 ELEQMQLILETIP--VIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEK 291
Query: 351 LIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPF 388
++ +NP RLT E L HP++ PE EP H PF
Sbjct: 292 ILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQH-PF 328
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 183 bits (464), Expect = 5e-46
Identities = 127/395 (32%), Positives = 209/395 (52%), Gaps = 47/395 (11%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +AIKK++ F + KRA REL
Sbjct: 56 STFTVLKRYQNLKPIGSGAQGIVCAAYDA---VLDRNVAIKKLSRPFQNQTHAKRAYREL 112
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
M H+NI+SL+++ + E + +Y EL+D +L +VI + + +
Sbjct: 113 VLMKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMEL--DHERMSYL 169
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR SF +T
Sbjct: 170 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--------MT 221
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E K +F G D + Q ++ + LG
Sbjct: 222 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLG 280
Query: 303 TP-------KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + ++FP +S+
Sbjct: 281 TPCPEFMKKLQPTVRNYVENR---------PKYAGLTFPKLFPDSLFPADSEHNKLKASQ 331
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P R++V++AL HP++ +P P +D ++ +++E +
Sbjct: 332 ARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWK 391
Query: 404 ECLCDEVSKFHNDRQTKDFVSPPLMTPHFIAESNS 438
E + EV +++ +TK+ V +P A ++S
Sbjct: 392 ELIYKEV--MNSEEKTKNGVVKGQPSPSGAAVNSS 424
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 183 bits (464), Expect = 5e-46
Identities = 127/395 (32%), Positives = 209/395 (52%), Gaps = 47/395 (11%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +AIKK++ F + KRA REL
Sbjct: 18 STFTVLKRYQNLKPIGSGAQGIVCAAYDA---VLDRNVAIKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
M H+NI+SL+++ + E + +Y EL+D +L +VI + + +
Sbjct: 75 VLMKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR SF +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E K +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLG 242
Query: 303 TP-------KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + ++FP +S+
Sbjct: 243 TPCPEFMKKLQPTVRNYVENR---------PKYAGLTFPKLFPDSLFPADSEHNKLKASQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P R++V++AL HP++ +P P +D ++ +++E +
Sbjct: 294 ARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWK 353
Query: 404 ECLCDEVSKFHNDRQTKDFVSPPLMTPHFIAESNS 438
E + EV +++ +TK+ V +P A ++S
Sbjct: 354 ELIYKEV--MNSEEKTKNGVVKGQPSPSGAAVNSS 386
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 182 bits (462), Expect = 9e-46
Identities = 124/380 (32%), Positives = 203/380 (52%), Gaps = 47/380 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D + +AIKK++ F + KRA REL
Sbjct: 56 STFTVLKRYQNLKPIGSGAQGIVCAAYDA---VLDRNVAIKKLSRPFQNQTHAKRAYREL 112
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
M H+NI+SL+++ + E + +Y EL+D +L +VI + + +
Sbjct: 113 VLMKCVN-HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMEL--DHERMSYL 169
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR SF +T
Sbjct: 170 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--------MT 221
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E K +F G D + Q ++ + LG
Sbjct: 222 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLG 280
Query: 303 TP-------KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +R Y +R P+Y + ++FP +S+
Sbjct: 281 TPCPEFMKKLQPTVRNYVENR---------PKYAGLTFPKLFPDSLFPADSEHNKLKASQ 331
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A DL+ +++ +P R++V++AL HP++ +P P +D ++ +++E +
Sbjct: 332 ARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWK 391
Query: 404 ECLCDEVSKFHNDRQTKDFV 423
E + EV +++ +TK+ V
Sbjct: 392 ELIYKEV--MNSEEKTKNGV 409
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 179 bits (454), Expect = 7e-45
Identities = 122/374 (32%), Positives = 197/374 (52%), Gaps = 48/374 (12%)
Query: 66 NFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELK 125
NF++ RY L+ +G G+ G V +A D + +AIKK++ F KRA RE K
Sbjct: 17 NFTIHSRYINLRPIGSGAQGIVCAAYDT---ITQQNVAIKKLSRPFQNVTHAKRAYREFK 73
Query: 126 FMSYFKGHRNIVSLIDLEIV--NEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFL 183
M H+NI+ L++ N E + +Y EL+D +L +VI ++ + + L
Sbjct: 74 LMKLVN-HKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDL--DHDRMSYLL 130
Query: 184 YQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITN 243
YQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR +F +T
Sbjct: 131 YQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFM--------MTP 182
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGT 303
YV TR+YRAPE+IL Y+++VD+W+VGCI+ E +F G D + Q +I + LGT
Sbjct: 183 YVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGT 241
Query: 304 PK-------QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP-------------YASSE 343
P Q +R Y +R P+Y + +FP +S+
Sbjct: 242 PSPSFMQRLQPTVRNYVENR---------PRYTGYSFDRLFPDGLFPNDNNQNSRRKASD 292
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLR 403
A +L+ +++ +PE R++V+EAL H ++ + E P+D + ++ +++E+ +
Sbjct: 293 ARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWK 352
Query: 404 ECLCDEVSKF--HN 415
E + +EV + HN
Sbjct: 353 ELIYEEVMDYEAHN 366
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 179 bits (453), Expect = 1e-44
Identities = 126/368 (34%), Positives = 197/368 (53%), Gaps = 47/368 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D E +AIKK++ F + KRA REL
Sbjct: 18 STFTVLKRYQNLKPIGSGAQGIVCAAYDA---ILERNVAIKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
M H+NI+ L+++ + E + +Y EL+D +L +VI + + +
Sbjct: 75 VLMKCVN-HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR SF +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E K +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLG 242
Query: 303 TP-------KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +RTY +R P+Y + ++FP +S+
Sbjct: 243 TPCPEFMKKLQPTVRTYVENR---------PKYAGYSFEKLFPDVLFPADSEHNKLKASQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNP-EAEPICPHGPFDFTYEKHLYSMERL 402
A DL+ +++ + R++V+EAL HP++ +P EAE P P D ++ +++E
Sbjct: 294 ARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIP-DKQLDEREHTIEEW 352
Query: 403 RECLCDEV 410
+E + EV
Sbjct: 353 KELIYKEV 360
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 179 bits (453), Expect = 1e-44
Identities = 126/368 (34%), Positives = 197/368 (53%), Gaps = 47/368 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D E +AIKK++ F + KRA REL
Sbjct: 18 STFTVLKRYQNLKPIGSGAQGIVCAAYDA---ILERNVAIKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
M H+NI+ L+++ + E + +Y EL+D +L +VI + + +
Sbjct: 75 VLMKCVN-HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR SF +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E K +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLG 242
Query: 303 TP-------KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +RTY +R P+Y + ++FP +S+
Sbjct: 243 TPCPEFMKKLQPTVRTYVENR---------PKYAGYSFEKLFPDVLFPADSEHNKLKASQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNP-EAEPICPHGPFDFTYEKHLYSMERL 402
A DL+ +++ + R++V+EAL HP++ +P EAE P P D ++ +++E
Sbjct: 294 ARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIP-DKQLDEREHTIEEW 352
Query: 403 RECLCDEV 410
+E + EV
Sbjct: 353 KELIYKEV 360
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 177 bits (448), Expect = 4e-44
Identities = 114/322 (35%), Positives = 180/322 (55%), Gaps = 33/322 (10%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
A V RY+ L+++G G+ G V SA D Q+AIKK++ F KRA REL
Sbjct: 111 AQMVVLKRYQNLRLIGSGAQGIVCSAFDT---VRNEQVAIKKLSRPFQNVTHAKRAYREL 167
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
K MS H+NI+ +++ + + ++ LY EL+D +L +VI ++ + +
Sbjct: 168 KLMSLVN-HKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMDL--DHERLSYL 224
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG++++HSA +IHRDLKP NI+ +KI DFGLAR +F +T
Sbjct: 225 LYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFM--------MT 276
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W++GCI E + +F G D + Q I + LG
Sbjct: 277 PYVVTRYYRAPEVILG-MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLG 335
Query: 303 TP-KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSEAVDLME 349
TP + + R + R Y ++P+Y+ TP+ +F ++A DL+
Sbjct: 336 TPDRSFLERLQPTVRNY---VENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLS 392
Query: 350 RLIDWNPEARLTVEEALDHPFL 371
R++ +PE R++V++AL HP++
Sbjct: 393 RMLVIDPERRISVDDALRHPYV 414
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 176 bits (446), Expect = 6e-44
Identities = 125/368 (33%), Positives = 196/368 (52%), Gaps = 47/368 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D E +AIKK++ F + KRA REL
Sbjct: 18 STFTVLKRYQNLKPIGSGAQGIVCAAYDA---ILERNVAIKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
M H+NI+ L+++ + E + +Y EL+D +L +VI + + +
Sbjct: 75 VLMKCVN-HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR SF +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLG 242
Query: 303 TP-------KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +RTY +R P+Y + ++FP +S+
Sbjct: 243 TPCPEFMKKLQPTVRTYVENR---------PKYAGYSFEKLFPDVLFPADSEHNKLKASQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNP-EAEPICPHGPFDFTYEKHLYSMERL 402
A DL+ +++ + R++V+EAL HP++ +P EAE P P D ++ +++E
Sbjct: 294 ARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIP-DKQLDEREHTIEEW 352
Query: 403 RECLCDEV 410
+E + EV
Sbjct: 353 KELIYKEV 360
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 176 bits (446), Expect = 6e-44
Identities = 125/368 (33%), Positives = 196/368 (52%), Gaps = 47/368 (12%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F+V RY+ L+ +G G+ G V +A D E +AIKK++ F + KRA REL
Sbjct: 18 STFTVLKRYQNLKPIGSGAQGIVCAAYDA---ILERNVAIKKLSRPFQNQTHAKRAYREL 74
Query: 125 KFMSYFKGHRNIVSLIDLEIVNE--EPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
M H+NI+ L+++ + E + +Y EL+D +L +VI + + +
Sbjct: 75 VLMKCVN-HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMEL--DHERMSYL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
LYQ+LCG+K++HSA +IHRDLKP NI+ +KI DFGLAR SF +T
Sbjct: 132 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM--------MT 183
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
YV TR+YRAPE+IL Y ++VD+W+VGCI+ E +F G D + Q ++ + LG
Sbjct: 184 PYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLG 242
Query: 303 TP-------KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP------------YASSE 343
TP Q +RTY +R P+Y + ++FP +S+
Sbjct: 243 TPCPEFMKKLQPTVRTYVENR---------PKYAGYSFEKLFPDVLFPADSEHNKLKASQ 293
Query: 344 AVDLMERLIDWNPEARLTVEEALDHPFLQQVRNP-EAEPICPHGPFDFTYEKHLYSMERL 402
A DL+ +++ + R++V+EAL HP++ +P EAE P P D ++ +++E
Sbjct: 294 ARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIP-DKQLDEREHTIEEW 352
Query: 403 RECLCDEV 410
+E + EV
Sbjct: 353 KELIYKEV 360
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 175 bits (444), Expect = 1e-43
Identities = 108/334 (32%), Positives = 176/334 (52%), Gaps = 23/334 (6%)
Query: 67 FSVPGRYEI----LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIR 122
F++P Y++ ++ LG GS+G V+ +AIKK+ F +R R
Sbjct: 108 FAIPEGYDVEPNSIEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFR 167
Query: 123 ELKFMSYFKGHRNIVSLIDLEIVNEE-PYSGLYCYQELVDYDLARVI-----HSNVLFSE 176
E K + + H NI+ +D+ +EE + +Y E L +++ + + ++
Sbjct: 168 ETKLLQLMR-HDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTD 226
Query: 177 FHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGG 236
HIK +YQI+ +KYIHSA++IHRDLKPGN+ + ++ I DFGLAR + T
Sbjct: 227 EHIKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDT---- 282
Query: 237 ISNHITNYVATRWYRAPELIL-SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVM 295
+T YV TRWYR+PE+I Y+ DMW++GCI AE +P+F G++ Q
Sbjct: 283 ---SLTQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQ 339
Query: 296 EIQKILGTPKQIVIRTY--GSSRCYDIFSTSKPQYKKTPWCEIFP--YASSEAVDLMERL 351
I ++ G+P + ++ +S S +K+ + ++F S + +DL+E+L
Sbjct: 340 RITQLCGSPDEELLTKIENDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKL 399
Query: 352 IDWNPEARLTVEEALDHPFLQQVRNPEAEPICPH 385
+ +PE R+TVEEA+ HP+L + PE EP H
Sbjct: 400 LVLDPEKRITVEEAIQHPYLAEFSLPEDEPRADH 433
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 174 bits (441), Expect = 2e-43
Identities = 99/273 (36%), Positives = 159/273 (57%), Gaps = 18/273 (6%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ VP RY+ L +G G+YG+V +A D +++A+KK++ F I KR REL+
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTG---LRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + K H N++ L+D+ + E ++ +Y L+ DL ++ L + H++ +Y
Sbjct: 75 LKHMK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD-HVQFLIY 132
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
QIL G+KYIHSAD+IHRDLKP N+ + E+KI DFGLAR + +T Y
Sbjct: 133 QILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD----------DEMTGY 182
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYRAPE++L+ Y+++VD+W+VGCI+AE + +F G D + Q+ I +++GTP
Sbjct: 183 VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF 337
+++ S + + S Q K + +F
Sbjct: 243 GAELLKKISSESARN-YIQSLTQMPKMNFANVF 274
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 174 bits (440), Expect = 3e-43
Identities = 126/409 (30%), Positives = 198/409 (47%), Gaps = 69/409 (16%)
Query: 69 VPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMS 128
+P Y L+ LG+G+YG V +A + PT + ++AIKK F I KR RELK +
Sbjct: 45 LPQWYNSLKPLGEGAYGVVCTA--EYEPTGD-RVAIKKFFRPFQSTIHAKRTYRELKLLR 101
Query: 129 YFKGHRNIVSLIDLEIVNEEPYS--GLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
+ H N++ +ID+ + + S +Y L+ DL ++ L E I+ +YQ+
Sbjct: 102 TLQ-HDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDE-QIQLLIYQV 159
Query: 187 LCGMKY-----------------------------IHSADVIHRDLKPGNILCSITGEIK 217
L G+KY IHSA +IHRDLKP NI + E+K
Sbjct: 160 LRGLKYMSHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVK 219
Query: 218 -----------------ICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHK 260
I DFGLAR +T YVATRWYRAPE++L+
Sbjct: 220 VFLSFSQLSFLILSFFKILDFGLARAQDAE----------MTGYVATRWYRAPEIMLNWM 269
Query: 261 RYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRCYDI 320
Y+++VD+W+VGCILAE +P+F G+D + Q+ +I ++GTPK+ S +
Sbjct: 270 HYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNY 329
Query: 321 FSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAE 380
P ++ + +FP AS A++L+E ++ +P+ R++V AL H +L++ P E
Sbjct: 330 IKNRSPIIRQ-DFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDE 388
Query: 381 PICPHGPFDFTY-----EKHLYSMERLRECLCDEVSKFHNDRQTKDFVS 424
P+ + E+ ++ RE + +E+ F N + FVS
Sbjct: 389 PVAMDTVINSIVTIDPAEERATTLSDWRELIWNEIRLFQNSARRLSFVS 437
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 173 bits (439), Expect = 4e-43
Identities = 95/250 (38%), Positives = 151/250 (60%), Gaps = 17/250 (6%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ VP RY+ L +G G+YG+V +A D +++A+KK++ F I KR REL+
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTG---LRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 127 MSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
+ + K H N++ L+D+ + E ++ +Y L+ DL ++ L + H++ +Y
Sbjct: 75 LKHMK-HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD-HVQFLIY 132
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
QIL G+KYIHSAD+IHRDLKP N+ + E+KI DFGLAR + +T Y
Sbjct: 133 QILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD----------DEMTGY 182
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYRAPE++L+ Y+++VD+W+VGCI+AE + +F G D + Q+ I +++GTP
Sbjct: 183 VATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
Query: 305 KQIVIRTYGS 314
+++ S
Sbjct: 243 GAELLKKISS 252
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 172 bits (437), Expect = 7e-43
Identities = 110/316 (34%), Positives = 166/316 (51%), Gaps = 32/316 (10%)
Query: 69 VPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMS 128
V RY +VLG+G+YG V A D E +AIKK+ RE + A+RE+K +
Sbjct: 8 VADRYLKQEVLGQGTYGVVFKATDTKT---EQTVAIKKIRLGKQREGVNITALREIKMLK 64
Query: 129 YFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIH-SNVLFSEFHIKHFLYQIL 187
K H +I+ LID E L+ E ++ DL VI SN+ S IK +L
Sbjct: 65 ELK-HPHIILLIDAFPHKEN----LHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMTF 119
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVAT 247
G+ Y H V+HRD+KP N+L + G++K+ DFGLAR + G + T+ V
Sbjct: 120 KGLAYCHDKWVLHRDMKPNNLLIGVDGQLKLADFGLAR-------IFGSPNRKFTHQVFA 172
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
RWYRAPEL+ K+Y +VD+WAV CI AE R+P GN + Q+ +I GTPK
Sbjct: 173 RWYRAPELLFGAKQYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPK-- 230
Query: 308 VIRTYGSSRCYDIFSTSKPQYKKTPWC------EIFPYASSEAVDLMERLIDWNPEARLT 361
+ + D+ T P Y + + +FP S +A+DL+ ++ ++P+AR++
Sbjct: 231 ------ADQWPDL--TKLPDYVEYQFVPAPSLRSLFPAVSDDALDLLSKMFTYDPKARIS 282
Query: 362 VEEALDHPFLQQVRNP 377
+++AL+H + P
Sbjct: 283 IKQALEHRYFTSAPAP 298
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 172 bits (436), Expect = 9e-43
Identities = 112/324 (34%), Positives = 181/324 (55%), Gaps = 24/324 (7%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+++I+ ++G+G+YG V A DK T E+ +A+KKV +E AIRE+K +
Sbjct: 726 KFDIIGIIGEGTYGQVYKARDKD--TGEL-VALKKVRLDNEKEGFPITAIREIKILRQLI 782
Query: 132 GHRNIVSLIDLEIVNEEPYS------GLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLY 184
HR++V++ ++ ++ Y E +D+DL ++ S ++ FSE HIK F+
Sbjct: 783 -HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMK 841
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q++ G++Y H + +HRD+K NIL + +G+IK+ DFGLAR + S TN
Sbjct: 842 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE------SRPYTNK 895
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V T WYR PEL+L +RY+ ++D+W+ GCIL E + +KP+F N L Q+ I ++ G+P
Sbjct: 896 VITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSP 955
Query: 305 KQIVIRTYGSSRCYDIFSTSKP--QYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
V + F+T KP QY++ E F + S A+DL++ ++ +P R T
Sbjct: 956 CPAV---WPDVIKLPYFNTMKPKKQYRRR-LREEFSFIPSAALDLLDHMLTLDPSKRCTA 1011
Query: 363 EEALDHPFLQQVR-NPEAEPICPH 385
E+ L FL+ V + A P PH
Sbjct: 1012 EQTLQSDFLKDVELSKMAPPDLPH 1035
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 172 bits (436), Expect = 9e-43
Identities = 113/311 (36%), Positives = 170/311 (54%), Gaps = 38/311 (12%)
Query: 72 RYEILQVLGKGSYGTVV--SAVDKGNPTHEVQLAIKKVTSIFT--REILLKRAIRELKFM 127
RY ++ LG G+YG+V+ +++ G +AIKK+ F E + +R ++ LK +
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGE-----LIAIKKMKRKFYSWEECMNQREVKSLKKL 57
Query: 128 SYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQI 186
+ H N+V L E++ E + LY E + +L ++I N LF E I++ +YQI
Sbjct: 58 N----HANVVKL--KEVIRENDH--LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGI--SPSFTVAGGISNHITNY 244
L G+ +IH HRDLKP N+LC +KI DFGLAR I P +T +Y
Sbjct: 110 LQGLAFIHKLGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYT----------DY 159
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V+TRWYRAPE++L YS +D+WAVGCI+AE Y +P+F G + + +I ++LGTP
Sbjct: 160 VSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
Query: 305 KQIVIRTYGSSRCYDIFSTSK---PQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
K+ Y + S PQ + P ASSEAV L+ ++ W+P+ R T
Sbjct: 220 KKT-----DWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPT 274
Query: 362 VEEALDHPFLQ 372
+AL +P+ Q
Sbjct: 275 ASQALRYPYFQ 285
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 171 bits (434), Expect = 2e-42
Identities = 113/322 (35%), Positives = 175/322 (54%), Gaps = 21/322 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L + +G+YG V A DK T E+ +A+KKV RE ++RE+ + F
Sbjct: 406 FERLNKIDEGTYGVVYRAKDK--KTGEI-VALKKVKMEKEREGFPLTSLREINILLSFH- 461
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H +IV + E+V ++ E +++DL ++ + FS+ +K + Q+L G+K
Sbjct: 462 HPSIVDV--KEVVVGSSLDSIFMVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGVK 519
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
Y+H V+HRDLK N+L + GE+KICDFGLAR G T+ V T WYR
Sbjct: 520 YLHDNWVLHRDLKTSNLLLNNRGELKICDFGLARQY-------GSPLKPYTHLVVTLWYR 572
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K+YS ++DMW++GCI+AE + P+F G Q+ +I +ILGTP + +
Sbjct: 573 APELLLGAKQYSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPG 632
Query: 312 YGSSRCYDIFSTSKPQY----KKTPWCEI--FPYASSEAVDLMERLIDWNPEARLTVEEA 365
+ + + K QY KK P P S DL+ +L+ ++PE R+TV EA
Sbjct: 633 FSKLPGVKV-NFVKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEA 691
Query: 366 LDHPFLQQVRNPEAEPICPHGP 387
L H + ++V P+++ P P
Sbjct: 692 LKHDWFREVPLPKSKDFMPTFP 713
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 171 bits (432), Expect = 3e-42
Identities = 113/311 (36%), Positives = 169/311 (54%), Gaps = 38/311 (12%)
Query: 72 RYEILQVLGKGSYGTVV--SAVDKGNPTHEVQLAIKKVTSIFT--REILLKRAIRELKFM 127
RY ++ LG G+YG+V+ +++ G +AIKK+ F E + R ++ LK +
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGE-----LIAIKKMKRKFYSWEECMNLREVKSLKKL 57
Query: 128 SYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQI 186
+ H N+V L E++ E + LY E + +L ++I N LF E I++ +YQI
Sbjct: 58 N----HANVVKL--KEVIRENDH--LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGI--SPSFTVAGGISNHITNY 244
L G+ +IH HRDLKP N+LC +KI DFGLAR I P +T +Y
Sbjct: 110 LQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYT----------DY 159
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V+TRWYRAPE++L YS +D+WAVGCI+AE Y +P+F G + + +I ++LGTP
Sbjct: 160 VSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
Query: 305 KQIVIRTYGSSRCYDIFSTSK---PQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
K+ Y + S PQ + P ASSEAV L+ ++ W+P+ R T
Sbjct: 220 KKT-----DWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPT 274
Query: 362 VEEALDHPFLQ 372
+AL +P+ Q
Sbjct: 275 ASQALRYPYFQ 285
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 170 bits (430), Expect = 4e-42
Identities = 111/318 (34%), Positives = 173/318 (53%), Gaps = 20/318 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +L +G+G+YG V AV+ N T E Q+A+K+V +E AIRE+K +
Sbjct: 311 YTMLDQIGEGTYGQVYKAVN--NLTGE-QVALKRVRLENEKEGFPITAIREIKILRQLH- 366
Query: 133 HRNIVSLIDLEIVN------EEPYSGLYCYQELVDYDLARVIHSNVL--FSEFHIKHFLY 184
H+NIV L+D+ I + + + Y E VD+DL ++ S L F++ I
Sbjct: 367 HKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFK 426
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q+L G+ YIH+ +HRD+K NIL + GE+KI D GLAR S TN
Sbjct: 427 QLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKE-------SRLYTNR 479
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V T WYR PEL+L +RY ++D+W+ GC+L E + RKP+F GN+ Q+ I K+ G+P
Sbjct: 480 VITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSP 539
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
++ F K Y++ E EAVDL+++++ NPE R++ +E
Sbjct: 540 NVDNWPELTELVGWNTF-RMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKE 598
Query: 365 ALDHPFLQQVRNPEAEPI 382
AL+HP+++ + + +P+
Sbjct: 599 ALNHPWIRSLEHTTVQPL 616
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 169 bits (429), Expect = 6e-42
Identities = 101/304 (33%), Positives = 162/304 (53%), Gaps = 17/304 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y+ L+ +G+G+YG V A+D + +A+KK+ E + AIRE+ + K
Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKD 67
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARV---IHSNVLFSEFHIKHFLYQILCG 189
NIV L D IV+ + + LY E +D DL R I + +K F+ Q+ G
Sbjct: 68 D-NIVRLYD--IVHSDAHK-LYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKG 123
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+ Y HS ++HRDLKP N+L + G +K+ DFGLAR T+ + T W
Sbjct: 124 IAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRA-------YTHEIVTLW 176
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YRAPE++L K+YS VD W++GCI AE RKP+F G+ + Q+ +I ++LGTP + +
Sbjct: 177 YRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAI- 235
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ F S PQ+++ ++ P +DL+++L+ ++P R++ A HP
Sbjct: 236 --WPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHP 293
Query: 370 FLQQ 373
+ Q+
Sbjct: 294 YFQE 297
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 169 bits (429), Expect = 6e-42
Identities = 112/318 (35%), Positives = 177/318 (55%), Gaps = 36/318 (11%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTR--EILLKRAIRELKFMSY 129
RY ++ LG G+YG+V+ + K N + E+ +AIK++ F E + R ++ LK ++
Sbjct: 3 RYTTMRQLGDGTYGSVL--MGKSNESGEL-VAIKRMKRKFYSWDECMNLREVKSLKKLN- 58
Query: 130 FKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILC 188
H N++ L E++ E + LY E + +L +++ N LF E I++ +YQIL
Sbjct: 59 ---HANVIKL--KEVIRENDH--LYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQ 111
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGI--SPSFTVAGGISNHITNYVA 246
G+ +IH HRD+KP N+LC +KI DFGLAR + P +T +YV+
Sbjct: 112 GLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYT----------DYVS 161
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
TRWYRAPE++L YS +D+WAVG I+AE Y +P+F G + ++ +I ++LGTPK+
Sbjct: 162 TRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKK 221
Query: 307 IVIRTYGSSRCYDIFSTSK---PQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVE 363
Y + S+ PQ + P AS+EA+ LM +++W+P+ R T
Sbjct: 222 -----SDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTAS 276
Query: 364 EALDHPFLQ--QVRNPEA 379
+AL HP+ Q QV P +
Sbjct: 277 QALKHPYFQVGQVLGPSS 294
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 169 bits (428), Expect = 8e-42
Identities = 110/319 (34%), Positives = 176/319 (54%), Gaps = 23/319 (7%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+++I+ ++G+G+YG V A DK T E+ +A+KKV +E AIRE+K +
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKD--TGEM-VALKKVRLDNEKEGFPITAIREIKILRQLT 760
Query: 132 GHRNIVSLIDLEIVNEEPYS------GLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLY 184
H++I+++ ++ E+ Y E +D+DL ++ S ++ F+E HIK F+
Sbjct: 761 -HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 819
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q++ G+ Y H + +HRD+K NIL + G+IK+ DFGLAR S S TN
Sbjct: 820 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEE------SRPYTNK 873
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V T WYR PEL+L +RY+ ++D+W+ GCIL E + +KP+F N L Q+ I +I G+P
Sbjct: 874 VITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSP 933
Query: 305 KQIVIRTYGSSRCYDIFSTSKP--QYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
V + F+T KP QY++ E F + + A+DL + ++ +P R T
Sbjct: 934 CPAV---WPDVIKLPYFNTMKPKKQYRR-KLREEFVFIPAAALDLFDYMLALDPSKRCTA 989
Query: 363 EEALDHPFLQQVRNPEAEP 381
E+AL FL+ V + P
Sbjct: 990 EQALQCEFLRDVEPSKMPP 1008
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 169 bits (428), Expect = 8e-42
Identities = 110/319 (34%), Positives = 176/319 (54%), Gaps = 23/319 (7%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+++I+ ++G+G+YG V A DK T E+ +A+KKV +E AIRE+K +
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKD--TGEM-VALKKVRLDNEKEGFPITAIREIKILRQLT 760
Query: 132 GHRNIVSLIDLEIVNEEPYS------GLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLY 184
H++I+++ ++ E+ Y E +D+DL ++ S ++ F+E HIK F+
Sbjct: 761 -HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMR 819
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q++ G+ Y H + +HRD+K NIL + G+IK+ DFGLAR S S TN
Sbjct: 820 QLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEE------SRPYTNK 873
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V T WYR PEL+L +RY+ ++D+W+ GCIL E + +KP+F N L Q+ I +I G+P
Sbjct: 874 VITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSP 933
Query: 305 KQIVIRTYGSSRCYDIFSTSKP--QYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
V + F+T KP QY++ E F + + A+DL + ++ +P R T
Sbjct: 934 CPAV---WPDVIKLPYFNTMKPKKQYRR-KLREEFVFIPAAALDLFDYMLALDPSKRCTA 989
Query: 363 EEALDHPFLQQVRNPEAEP 381
E+AL FL+ V + P
Sbjct: 990 EQALQCEFLRDVEPSKMPP 1008
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 169 bits (427), Expect = 1e-41
Identities = 118/369 (31%), Positives = 188/369 (49%), Gaps = 31/369 (8%)
Query: 65 ANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIREL 124
+ F++P RY L L G+ GTVV A D ++AIKK+ F + KRA RE
Sbjct: 30 STFTIPTRYVNLSFLNAGAQGTVVMADDLVTTQ---RVAIKKMQQPFVMTMSAKRAYREF 86
Query: 125 KFMSYFKGHRNIVSLIDLEIVNEE--PYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
++ K H NI+ L++ + + +Y EL+ ++L VIH + + F
Sbjct: 87 ILLTTIK-HPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIH-RLRLDHKTLSFF 144
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
+YQ LC +K++H++ VIHRDLKP NI+ + +K+ DFGLAR + S ++
Sbjct: 145 VYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVD------TSMRMS 198
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+YV TR+YRAPE+IL YS+ VD+W+VGCI AE +F G D + Q +I +LG
Sbjct: 199 DYVVTRYYRAPEVILG-LPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLG 257
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFP--------------YASSEAVDLM 348
TP I G S ++ S P+++ + EI P A DL+
Sbjct: 258 TPDDHFISQLGQSAA--MYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLL 315
Query: 349 ERLIDWNPEARLTVEEALDHPFLQ-QVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLC 407
++ NPE R +VE+AL+HP+++ ++ E +D + ++ +E +
Sbjct: 316 FNMLKINPEERYSVEDALNHPYVKLWFKDDEVNAPASENRYDQEIDFADKTLIEWKELIF 375
Query: 408 DEVSKFHND 416
+EV ++ D
Sbjct: 376 NEVQRYQAD 384
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 169 bits (427), Expect = 1e-41
Identities = 114/305 (37%), Positives = 175/305 (57%), Gaps = 31/305 (10%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFT--REILLKRAIRELKFMSY 129
RY+IL+ LG G+ G+V AV+ T+EV +A+KK+ F E + R ++ L+ ++
Sbjct: 11 RYKILEELGDGTCGSVYKAVNL--ETYEV-VAVKKMKRKFYYWEECVNLREVKALRKLN- 66
Query: 130 FKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILC 188
H +I+ L EIV E ++ L+ E +D++L ++ FSE I+ F+ Q+L
Sbjct: 67 ---HPHIIKL--KEIVRE--HNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQ 119
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS--PSFTVAGGISNHITNYVA 246
G+ ++H HRDLKP N+L + +KI DFGLAR ++ P +T YV+
Sbjct: 120 GLAHMHKNGYFHRDLKPENLLVT-NNILKIADFGLAREVASMPPYT----------EYVS 168
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
TRWYRAPE++L Y+ +VDMWAVG ILAE Y P+F G + Q+ +I +LG P
Sbjct: 169 TRWYRAPEVLLQSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDW 228
Query: 307 IVIRTYGSSRCYD-IFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
T+ ++ I S S ++ +T ++ P A+ EA+DL+ RL W+P R T +EA
Sbjct: 229 ---TTFPEAKSISRIMSISHTEFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEA 285
Query: 366 LDHPF 370
L+HPF
Sbjct: 286 LNHPF 290
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 166 bits (421), Expect = 5e-41
Identities = 106/311 (34%), Positives = 163/311 (52%), Gaps = 22/311 (7%)
Query: 69 VPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMS 128
V RY +VLG+G+YG V A D N +AIKK+ +E + A+RE+K +
Sbjct: 7 VADRYLKREVLGQGTYGVVFKATDTKNGE---TVAIKKIRLGKEKEGVNVTALREIKLLK 63
Query: 129 YFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQIL 187
K H +I+ LID E L+ E ++ DL VI N+ S +K +L IL
Sbjct: 64 ELK-HPHIIELIDAFPHKEN----LHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMIL 118
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVAT 247
G++Y H V+HRD+KP N+L G++K+ DFGLAR + G T+ V
Sbjct: 119 KGLEYCHGKWVLHRDMKPNNLLIGPNGQLKLADFGLAR-------IFGSPGRKFTHQVFA 171
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
RWYRAPEL+ K+Y +VD+WA GCI AE R+P GN + Q+ +I GTPK
Sbjct: 172 RWYRAPELLFGAKQYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPK-- 229
Query: 308 VIRTYGSSRCYDIFSTSKPQYKKTPWC-EIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
+ C + + Q+ P + P S +A+DL+ ++ ++P++R+++++AL
Sbjct: 230 -ADQWPDMICLPDY--VEYQFVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQQAL 286
Query: 367 DHPFLQQVRNP 377
H + +P
Sbjct: 287 KHRYFTSAPSP 297
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 165 bits (418), Expect = 1e-40
Identities = 109/328 (33%), Positives = 170/328 (51%), Gaps = 28/328 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLK-RAIRELKFMSYFK 131
++ L + +G+YG V A D+ IK F E ++RE+ +
Sbjct: 297 FQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLSCN 356
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI-HSNVLFSEFHIKHFLYQILCGM 190
H IV++ ++ +V + + +Y E +++DL V+ FS +K + Q+L G+
Sbjct: 357 -HPAIVNVKEV-VVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLMMQLLDGL 414
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
KY+H+ +IHRDLKP N+L + GE+KICDFG+AR G T V T+WY
Sbjct: 415 KYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQY-------GSPIKPYTQMVITQWY 467
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
R PEL+L K YS +VDMW+VGCI+AE +KP+F G L Q+ +I +LGTP + +
Sbjct: 468 RPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWP 527
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEI---FP--------YASSEAVDLMERLIDWNPEAR 359
+ S F +K ++ P+ + FP S DL+ L+ +PE R
Sbjct: 528 GFSS------FPNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKR 581
Query: 360 LTVEEALDHPFLQQVRNPEAEPICPHGP 387
LTVE+AL+H + +V P+++ P P
Sbjct: 582 LTVEDALNHGWFHEVPLPKSKDFMPTYP 609
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 165 bits (418), Expect = 1e-40
Identities = 102/316 (32%), Positives = 174/316 (54%), Gaps = 19/316 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E++ +G+G+YG V A D + T+++ +A+KKV +E A+RE+K +
Sbjct: 804 FEMIAQIGEGTYGQVYKARD--HHTNDM-VALKKVRLEHEKEGFPITAVREIKILRQLN- 859
Query: 133 HRNIVSLIDLEIVNEEPYS------GLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQ 185
HRNIV+L ++ ++ Y E +D+DL ++ S ++ F+E + + Q
Sbjct: 860 HRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQ 919
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+ Y H + +HRD+K NIL + G++K+ DFGLAR + A TN V
Sbjct: 920 LLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYN-----ADDRERPYTNKV 974
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
T WYR PEL+L +RY S+D+W+ GCIL E + ++P+F N + Q+ I KI G+P
Sbjct: 975 ITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPV 1034
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
V + K ++ E F + + A+DL+++++D +P+ R+T E+A
Sbjct: 1035 PAVWPNVIKLPLFHTLKQKKTHRRRLR--EDFEFMPAPALDLLDKMLDLDPDKRITAEDA 1092
Query: 366 LDHPFLQQVRNPEAEP 381
L P+L+++ NP+ P
Sbjct: 1093 LRSPWLRKI-NPDEMP 1107
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 165 bits (417), Expect = 1e-40
Identities = 112/306 (36%), Positives = 167/306 (53%), Gaps = 21/306 (6%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE ++ +G+G+YG V A DK T+E +A+KK+ E + AIRE+ + +
Sbjct: 3 QYEKVEKIGEGTYGVVYKARDK--VTNET-IALKKIRLEQEDEGVPSTAIREISLLKEMQ 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFS-EFH-IKHFLYQILCG 189
H NIV D +V+ E LY E +D DL + + S FS + H IK +LYQIL G
Sbjct: 60 -HSNIVKYDD--VVHSE--KRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRG 114
Query: 190 MKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
+ Y HS V+HRDLKP N+L T +K+ DFGLAR G T+ V T
Sbjct: 115 IAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAF-------GIPVRTFTHEVVTL 167
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYRAPE++L YS VD+W+VGCI AE +KP+F G+ + Q+ +I +I+GTP +
Sbjct: 168 WYRAPEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDT 227
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
R S Y ++ P++K T P + VDL+ +++ +P R+ AL+H
Sbjct: 228 WRGVTSLPDY---KSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEH 284
Query: 369 PFLQQV 374
+ + +
Sbjct: 285 EYFKDL 290
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 164 bits (416), Expect = 2e-40
Identities = 110/312 (35%), Positives = 168/312 (53%), Gaps = 25/312 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ ++ +G+G+YG V A K T ++ +A+KK+ E + AIRE+ + K
Sbjct: 4 FQKVEKIGEGTYGVVYKA--KNRETGQL-VALKKIRLDLEMEGVPSTAIREISLLKELK- 59
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFH---IKHFLYQILCG 189
H NIV L+D+ + NE LY E + DL + + S SE IK +L+Q+L G
Sbjct: 60 HPNIVRLLDV-VHNERK---LYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQG 114
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+ + HS VIHRDLKP N+L + G IK+ DFGLAR T+ V T W
Sbjct: 115 VSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRT-------YTHEVVTLW 167
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YRAPE++L K Y+ +VD+W++GCI AE RK +F G+ + Q+ I ++LGTP +
Sbjct: 168 YRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSE--- 224
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
T+ + S P++ + EI P E DL+ +L+ ++P R+T + AL HP
Sbjct: 225 DTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHP 284
Query: 370 FLQQVRNPEAEP 381
+ +PE P
Sbjct: 285 YFS---SPEPSP 293
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 164 bits (415), Expect = 2e-40
Identities = 96/260 (36%), Positives = 139/260 (52%), Gaps = 24/260 (9%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RY + + LG+G+YG V AVD+ T EV +AIKK+ F + +R RE+ + F
Sbjct: 12 RYLLRRQLGQGAYGIVWKAVDRR--TGEV-VAIKKIFDAFRDKTDAQRTFREITLLQEFG 68
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELV-----------------DYDLARVIHSNVLF 174
H NI+SL+D ++ E +Y E + D DL VI L
Sbjct: 69 DHPNIISLLD--VIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAVIRKGGLL 126
Query: 175 SEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVA 234
+ H++ YQ+L +++HS V+HRD KP N+L +K+CDFGLAR +
Sbjct: 127 QDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGD--LPE 184
Query: 235 GGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQV 294
G +T YVATRWYRAPE++LS RY+ VDMW++GCIL E +P+F G +LHQ+
Sbjct: 185 GPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQL 244
Query: 295 MEIQKILGTPKQIVIRTYGS 314
I + + P + + GS
Sbjct: 245 ELILETIPPPSEEDLLALGS 264
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 164 bits (415), Expect = 2e-40
Identities = 105/307 (34%), Positives = 169/307 (54%), Gaps = 20/307 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ ++ +G+G+YG V A +K T EV +A+KK+ E + AIRE+ +
Sbjct: 4 FQKVEKIGEGTYGVVYKARNK--LTGEV-VALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL--FSEFHIKHFLYQILCGM 190
H NIV L+D +++ E + LY E + DL + + ++ L IK +L+Q+L G+
Sbjct: 60 HPNIVKLLD--VIHTE--NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGL 115
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
+ HS V+HRDLKP N+L + G IK+ DFGLAR G T+ V T WY
Sbjct: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-------GVPVRTYTHEVVTLWY 168
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
RAPE++L K YS +VD+W++GCI AE R+ +F G+ + Q+ I + LGTP ++V
Sbjct: 169 RAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWP 228
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
S Y S P++ + + ++ P + L+ +++ ++P R++ + AL HPF
Sbjct: 229 GVTSMPDY---KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPF 285
Query: 371 LQQVRNP 377
Q V P
Sbjct: 286 FQDVTKP 292
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 164 bits (415), Expect = 2e-40
Identities = 110/308 (35%), Positives = 165/308 (52%), Gaps = 25/308 (8%)
Query: 72 RYEILQVLGKGSYGTVVSAVDK-----GNPTHEVQLAIKKVTS-IFTREILLKRAIRELK 125
RY +L+ +G G++G V AV+K G VQ+AIK++ F+ E + +RE+K
Sbjct: 3 RYTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMKKKYFSWEECVN--LREVK 60
Query: 126 FMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLY 184
+S H NIV L E++ E LY E ++ +L +++ F+E I+++ +
Sbjct: 61 SLSRMN-HPNIVKL--KEVIRENDI--LYFVFEYMECNLYQLMKDRPKHFAESDIRNWCF 115
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q+ G+ Y+H HRDLKP N+L S IKI D GLAR I S T Y
Sbjct: 116 QVFQGLSYMHQRGYFHRDLKPENLLVS-KDVIKIADLGLAREIDSS--------PPYTEY 166
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V+TRWYRAPE++L Y+ VDMWA+G I+AE +P+F G ++ +I ++G+P
Sbjct: 167 VSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSP 226
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+ + + PQ+ + PYAS++AV+L+ERL W+P R T E
Sbjct: 227 TEET--WLEGLNLASVINYQFPQFPGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAE 284
Query: 365 ALDHPFLQ 372
AL HPF Q
Sbjct: 285 ALQHPFFQ 292
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 163 bits (412), Expect = 5e-40
Identities = 111/319 (34%), Positives = 172/319 (53%), Gaps = 24/319 (7%)
Query: 68 SVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFM 127
+V ++EIL V+G+G+YG V+ K THE+ +AIKK E + + +RELK +
Sbjct: 8 NVMNKFEILGVVGEGAYGVVLKCRHK--ETHEI-VAIKKFKDSEENEEVKETTLRELKML 64
Query: 128 SYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS--NVLFSEFHIKHFLYQ 185
K NIV L + LY E V+ ++ ++ N + E +K ++YQ
Sbjct: 65 RTLK-QENIVELKEAF----RRRGKLYLVFEYVEKNMLELLEEMPNGVPPE-KVKSYIYQ 118
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
++ + + H D++HRD+KP N+L S +K+CDFG AR +S G + + T YV
Sbjct: 119 LIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSE------GNNANYTEYV 172
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG-TP 304
ATRWYR+PEL+L Y KSVDMW+VGCIL E +P+F G + Q+ IQK+LG P
Sbjct: 173 ATRWYRSPELLLG-APYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLP 231
Query: 305 KQIVIRTYGSSRCYDIF--STSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
+ + Y + R + + + + PQ + + I +S +DLM+ L+ +P R
Sbjct: 232 SEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGIL---NSVLLDLMKNLLKLDPADRYLT 288
Query: 363 EEALDHPFLQQVRNPEAEP 381
E+ L+HP Q R + P
Sbjct: 289 EQCLNHPTFQTQRLLDRSP 307
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 162 bits (410), Expect = 9e-40
Identities = 106/321 (33%), Positives = 164/321 (51%), Gaps = 25/321 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YEIL+ + +GSYG V +DK T +A+KK+ ++RE++ +S +
Sbjct: 74 YEILEKIEEGSYGIVYRGLDKSTNT---LVALKKIKFDPNGIGFPITSLREIESLSSIR- 129
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILCGMK 191
H NIV L ++V + +Y E +++DL ++ + F + +K + Q+L
Sbjct: 130 HDNIVELE--KVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATA 187
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H +HRDLKP N+L + TGEIK+ DFGLAR +S + +T V T WYR
Sbjct: 188 FMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEP-------KSSLTRLVVTLWYR 240
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP-----KQ 306
APEL+L Y K +DMW++GCI AE R P+F G L Q+ +I +LG P Q
Sbjct: 241 APELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQ 300
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
+ Y + I + P + K P + A DL+ RL+ NP R++ +EAL
Sbjct: 301 YFLLPYANK----IKHPTVPTHSKIR--TSIPNLTGNAYDLLNRLLSLNPAKRISAKEAL 354
Query: 367 DHPFLQQVRNPEAEPICPHGP 387
+HP+ + P+ P P
Sbjct: 355 EHPYFYESPRPKDPKFFPTFP 375
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 162 bits (409), Expect = 1e-39
Identities = 108/315 (34%), Positives = 157/315 (49%), Gaps = 19/315 (6%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RY L LG+G + TV A D IKK + R+ + + A+RE+K + +
Sbjct: 11 RYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQ 70
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSN-VLFSEFHIKHFLYQILCGM 190
H NI+ L+D+ S + + +D DL +I N ++ ++ +IK + L G+
Sbjct: 71 -HENIIGLVDVF----GQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGL 125
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHI-TNYVATRW 249
+Y+H ++HRDLKP N+L + G +KI DFGLA+ G N I T++V TRW
Sbjct: 126 EYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSF--------GSPNRIYTHHVVTRW 177
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YR+PEL+ ++Y VDMWAVGCILAE R P G+ L Q+ I LGTP +
Sbjct: 178 YRSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEW 237
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
Y F + TP IF A ++ + LM+RL NP R++ EAL P
Sbjct: 238 PHLSKLHDYLQFR----NFPGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMP 293
Query: 370 FLQQVRNPEAEPICP 384
+ P P P
Sbjct: 294 YFANKPAPTVGPKLP 308
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 161 bits (408), Expect = 2e-39
Identities = 110/349 (31%), Positives = 174/349 (49%), Gaps = 28/349 (8%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
LG+G++G V + + Q+A+KK+ +++ A RE+ + H+NI+
Sbjct: 66 LGQGTFGEVYKGIHLET---QRQVAMKKIIVSVEKDLFPITAQREITILKRLN-HKNIIK 121
Query: 139 LIDL------EIVNEEP---YSGLYCYQELVDYDLARVIHSNVLFSEF-HIKHFLYQILC 188
LI++ +I N + Y + DL+ V+H+ + E IK+ + QIL
Sbjct: 122 LIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILE 181
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLAR---GISPSFTVAGGISN--HITN 243
G+ YIH A +HRD+K NIL G +K+ DFGLAR G P+ GG + T+
Sbjct: 182 GLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTS 241
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGT 303
V TRWYRAPEL+L K+Y+ +VD+W VGC+ AEF+ +KP+ G + Q I K+LGT
Sbjct: 242 VVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGT 301
Query: 304 PKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVE 363
P + + +R + YK T Y S +D + +L+ +P RLT
Sbjct: 302 PTE---EDWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAM 358
Query: 364 EALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSK 412
A HP+ ++ P + P T E H ++R +E + +S+
Sbjct: 359 SAKHHPWFKEDPLPSEKITLP------TEESHEADIKRYKEEMHQSLSQ 401
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 161 bits (407), Expect = 2e-39
Identities = 101/307 (32%), Positives = 158/307 (50%), Gaps = 19/307 (6%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G+G+Y V K ++AIKK+ ++ + A+RE+KF+ + H N++
Sbjct: 17 VGEGTYAVVFLGRQKETNR---RVAIKKIKVGQFKDGIDISALREIKFLRESR-HDNVIE 72
Query: 139 LIDLEIVNEEPYSGLYCYQELVDYDLARVIHSN-VLFSEFHIKHFLYQILCGMKYIHSAD 197
L+D+ S L E +D DL +I ++F HIK ++ +L G+ +IHS
Sbjct: 73 LVDVFSTK----SNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRF 128
Query: 198 VIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELIL 257
++HRDLKP N+L S G +K+ DFGL+R G +H+++ V TRWYR PEL +
Sbjct: 129 ILHRDLKPNNLLISSDGVLKLADFGLSRDF--------GTPSHMSHQVITRWYRPPELFM 180
Query: 258 SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRC 317
+ Y VDMW+VGCI AE R P G L Q+ I + LGTP+ VI++
Sbjct: 181 GCRSYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPN 240
Query: 318 YDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNP 377
Y P +F A E +DL++ ++D+NP R T ++AL+H + + P
Sbjct: 241 YVEMKHIPPPNGGME--ALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPKP 298
Query: 378 EAEPICP 384
+ P
Sbjct: 299 THPSLLP 305
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 161 bits (407), Expect = 2e-39
Identities = 126/354 (35%), Positives = 180/354 (50%), Gaps = 45/354 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS---IFTREILLKRAIR-----EL 124
Y V+G GS+G V A K T E ++AIKKV RE+ + R + EL
Sbjct: 102 YRAEHVIGTGSFGVVFQA--KCLETEE-KVAIKKVLQDKRYKNRELQIMRMLDHPNVVEL 158
Query: 125 KFMSYFKGHRNIVSL-IDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFL 183
K + ++ + L + LE V E Y Y ++ N +I+ +
Sbjct: 159 KHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKM-----------NQHMPLIYIQLYT 207
Query: 184 YQILCGMKYIHSA-DVIHRDLKPGNILCS-ITGEIKICDFGLARGISPSFTVAGGISNHI 241
YQI M Y+H V HRD+KP N+L + +T E+KICDFG A+ + P G N
Sbjct: 208 YQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLIP------GEPN-- 259
Query: 242 TNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKIL 301
+Y+ +R+YRAPELI Y+ ++DMW+VGC++AE + P+F G S+ Q++EI KIL
Sbjct: 260 ISYICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKIL 319
Query: 302 GTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARL 360
GTP + I+ Y+ F PQ K PW +IF S EA+DL RL+ ++P R
Sbjct: 320 GTPAREEIKNMNPR--YNDFKF--PQIKAQPWHKIFRRQVSPEAMDLASRLLQYSPNLRC 375
Query: 361 TVEEALDHPFLQQVRNPEAEPICPHGP-----FDFTYEKHLYSMERLRECLCDE 409
T EA HPF +R+P A P+G FDFT ++ + LR L E
Sbjct: 376 TALEACAHPFFDDLRDPRAS--LPNGRALPPLFDFTAQELAGASVELRHRLIPE 427
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 159 bits (403), Expect = 6e-39
Identities = 106/309 (34%), Positives = 158/309 (50%), Gaps = 24/309 (7%)
Query: 72 RYEILQVLGKGSYGTVVSAVD-KGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYF 130
RY Q+LG+G+YG V A D K T +A+KK+ +E + A+RE+K +
Sbjct: 12 RYLRRQILGEGTYGVVYKATDTKTGKT----VAVKKIRLGNQKEGVNFTALREIKLLKEL 67
Query: 131 KGHRNIVSLIDLEIVNEEPYSG-LYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILC 188
H +IV LID P+ G L+ E + DL VI N+ S IK ++ L
Sbjct: 68 N-HPHIVELIDAF-----PHDGSLHLVFEYMQTDLEAVIRDRNIFLSPGDIKSYMLMTLK 121
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
G+ Y H V+HRD+KP N+L G +K+ DFGLAR + G + T+ V
Sbjct: 122 GLAYCHKKWVLHRDMKPNNLLIGENGLLKLADFGLAR-------LFGSPNRRFTHQVFAT 174
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYRAPEL+ ++Y VD+WA GCI AE R+P G+ + Q+ +I + GTP
Sbjct: 175 WYRAPELLFGSRQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTP---- 230
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
+ + S Y P IFP AS +A+DL+ ++ ++P R+T+++ALDH
Sbjct: 231 VPSQWSDMIYLPDYMEFSYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDH 290
Query: 369 PFLQQVRNP 377
+ +P
Sbjct: 291 RYFSSSPSP 299
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 159 bits (402), Expect = 8e-39
Identities = 111/315 (35%), Positives = 163/315 (51%), Gaps = 34/315 (10%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE L+ +G+G+YGTV A K THE+ +A+K+V E + A+RE+ + K
Sbjct: 3 KYEKLEKIGEGTYGTVFKA--KNRETHEI-VALKRVRLDDDDEGVPSSALREICLLKELK 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGM 190
H+NIV L D+ +++ L E D DL + S N +K FL+Q+L G+
Sbjct: 60 -HKNIVRLHDVLHSDKK----LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGL 114
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
+ HS +V+HRDLKP N+L + GE+K+ DFGLAR G + V T WY
Sbjct: 115 GFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAF-------GIPVRCYSAEVVTLWY 167
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGR-KPVFMGNDSLHQVMEIQKILGTPKQIVI 309
R P+++ K YS S+DMW+ GCI AE +P+F GND Q+ I ++LGTP +
Sbjct: 168 RPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTE--- 224
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPW-------CEIFPYASSEAVDLMERLIDWNPEARLTV 362
+ S T P YK P + P ++ DL++ L+ NP R++
Sbjct: 225 EQWPS-------MTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISA 277
Query: 363 EEALDHPFLQQVRNP 377
EEAL HP+ P
Sbjct: 278 EEALQHPYFSDFCPP 292
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 157 bits (398), Expect = 2e-38
Identities = 106/346 (30%), Positives = 173/346 (49%), Gaps = 28/346 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +++ LG+G++G V + + + A+K++ +E AIRE+K + K
Sbjct: 36 YHLMEKLGEGTFGEVYKSQRRKDGK---VYALKRILMHTEKEGFPITAIREIKILKSIK- 91
Query: 133 HRNIVSLIDLEIVNEEPY----SGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQIL 187
H NI+ L D+ +V + +Y +D+DL+ ++ + +V F+E IK ++ Q+
Sbjct: 92 HENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLF 151
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGIS------NHI 241
G KY+H ++HRDLK N+L G +KI DFGLAR I+
Sbjct: 152 AGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREY 211
Query: 242 TNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKIL 301
T V TRWYR+PEL+L +RY+ ++DMW+VGCI+AE Y +P+ G+ L Q+ +I ++
Sbjct: 212 TGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLC 271
Query: 302 GTPKQIVIRTYGS-SRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARL 360
G+P Q + + C + S P + +T F + E L ++ NP+ RL
Sbjct: 272 GSPTQATMPNWEKLPGCEGV--RSFPSHPRTLETAFFTF-GKEMTSLCGAILTLNPDERL 328
Query: 361 TVEEALDHPFLQQVRNPEAEPICPHGPFDF-TYE-KHLYSMERLRE 404
+ AL+H + P P P + +Y H Y R RE
Sbjct: 329 SASMALEHEYF-------TTPPYPANPSELQSYSASHEYDKRRKRE 367
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 157 bits (398), Expect = 2e-38
Identities = 99/305 (32%), Positives = 158/305 (51%), Gaps = 14/305 (4%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE L +G+G++G V A + ++A+KKV +E A+RE+K + K
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQ---KVALKKVLMENEKEGFPITALREIKILQLLK 74
Query: 132 GHRNIVSLIDLEIVNEEPYS----GLYCYQELVDYDLARVIHSNVL--FSEFHIKHFLYQ 185
H N+V+LI++ PY+ +Y + ++DLA ++ SNVL F+ IK +
Sbjct: 75 -HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLL-SNVLVKFTLSEIKRVMQM 132
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+ YIH ++HRD+K N+L + G +K+ DFGLAR S N TN V
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS---LAKNSQPNRYTNRV 189
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
T WYR PEL+L + Y +D+W GCI+AE + R P+ GN HQ+ I ++ G+
Sbjct: 190 VTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSIT 249
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
V + Y+ K Q +K A+DL+++L+ +P R+ ++A
Sbjct: 250 PEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDA 309
Query: 366 LDHPF 370
L+H F
Sbjct: 310 LNHDF 314
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 157 bits (397), Expect = 3e-38
Identities = 102/318 (32%), Positives = 166/318 (52%), Gaps = 29/318 (9%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE L+ +G+G+YG V A++K T +A+KK E + A+RE+ +
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEK---TTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 132 GHRNIVSLIDLE--------IVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFH----- 178
IV L+ +E V+ P S LY E +D DL + I S+ S
Sbjct: 60 QSIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEAS 119
Query: 179 -IKHFLYQILCGMKYIHSADVIHRDLKPGNILCSIT-GEIKICDFGLARGISPSFTVAGG 236
++ F++Q+ G+ + HS V+HRDLKP N+L G +KI D GL+R +FTV
Sbjct: 120 LVQRFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSR----AFTVP-- 173
Query: 237 ISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVME 296
T+ + T WYRAPE++L YS +VD+W+VGCI AE R+ +F G+ Q++
Sbjct: 174 -LKAYTHEIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLH 232
Query: 297 IQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNP 356
I ++LGTP + + R + ++ P+++ P S E +DL+ +++ +NP
Sbjct: 233 IFRLLGTPTEQQWPGVMALRDWHVY----PKWEPQDLSRAVPSLSPEGIDLLTQMLKYNP 288
Query: 357 EARLTVEEALDHPFLQQV 374
R++ + ALDHP+ +
Sbjct: 289 AERISAKAALDHPYFDSL 306
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 157 bits (397), Expect = 3e-38
Identities = 127/358 (35%), Positives = 182/358 (50%), Gaps = 41/358 (11%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +V+G GS+G V A K T E +AIKKV + REL+ M
Sbjct: 72 YMAERVVGTGSFGIVFQA--KCLETGE-SVAIKKVLQD------RRYKNRELQLMRLMD- 121
Query: 133 HRNIVSLIDL---EIVNEEPYSGLYCYQELVDYDLARVIH----SNVLFSEFHIKHFLYQ 185
H N+VSL +E + L E V L RV+ SN F++K + YQ
Sbjct: 122 HPNVVSLKHCFFSTTTRDELFLNLV--MEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQ 179
Query: 186 ILCGMKYIHSAD-VIHRDLKPGNILCS-ITGEIKICDFGLARGISPSFTVAGGISNHITN 243
I G+ YIH+A V HRD+KP N+L +T + K+CDFG A+ + G +N +
Sbjct: 180 IFRGLAYIHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAK------VLVKGEAN--IS 231
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGT 303
Y+ +R+YRAPELI Y+ S+D+W+ GC+LAE +P+F G +S+ Q++EI K+LGT
Sbjct: 232 YICSRYYRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGT 291
Query: 304 PKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTV 362
P + IR + Y F PQ K PW ++F EA+DL RL+ ++P R T
Sbjct: 292 PTREEIRCMNPN--YTDFRF--PQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTA 347
Query: 363 EEALDHPFLQQVRNPEAEPICPHGP-----FDFTYEKHLYSMERLRECLCDEVSKFHN 415
EA HPF ++R P A P+G F+F E S E + + + V + N
Sbjct: 348 LEACAHPFFNELREPNAR--LPNGRPLPPLFNFKQELSGASPELINRLIPEHVRRQMN 403
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 157 bits (396), Expect = 4e-38
Identities = 111/322 (34%), Positives = 160/322 (49%), Gaps = 28/322 (8%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREI---LLKRAIRELKFMS 128
RYE L LG+G + TV A DK T+++ +AIKK+ E + + A+RE+K +
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKN--TNQI-VAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 129 YFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQIL 187
H NI+ L+D S + + ++ DL +I N L + HIK ++ L
Sbjct: 68 ELS-HPNIIGLLDAF----GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTL 122
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVAT 247
G++Y+H ++HRDLKP N+L G +K+ DFGLA+ G + T+ V T
Sbjct: 123 QGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSF-------GSPNRAYTHQVVT 175
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
RWYRAPEL+ + Y VDMWAVGCILAE R P G+ L Q+ I + LGTP +
Sbjct: 176 RWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEE 235
Query: 308 VIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALD 367
S Y F + + P IF A + +DL++ L +NP AR+T +AL
Sbjct: 236 QWPDMCSLPDYVTFKS----FPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALK 291
Query: 368 HPFLQQVRNPE-----AEPICP 384
+ P P CP
Sbjct: 292 MKYFSNRPGPTPGCQLPRPNCP 313
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 157 bits (396), Expect = 4e-38
Identities = 102/320 (31%), Positives = 166/320 (51%), Gaps = 31/320 (9%)
Query: 71 GRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYF 130
GR+ L+ +G+G+YG V A+ + V+ A+K + + E + +RE+ +
Sbjct: 43 GRFCSLRRIGEGTYGVVFKAI---HVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDL 99
Query: 131 KGHRNIVSLIDLEIVNE---------EPYSG---LYCYQELVDYDLARVIH----SNVLF 174
+ H NIV+L D+ + E +S LY E +D DL ++ +N +
Sbjct: 100 Q-HDNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVL 158
Query: 175 SEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVA 234
++K F++Q+L + Y H ++HRDLKP NIL S +G IKI DFGLAR S
Sbjct: 159 PPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFSFP---- 214
Query: 235 GGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQV 294
S + T+ V T WYR PE++L +RYS S+DMW++GCI +E KP+F G + Q+
Sbjct: 215 ---SRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQL 271
Query: 295 MEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYK-KTPWCEIFPYASSEAVDLMERLID 353
+I +I+GTP I+++ + + PQ+ E + +D++ ++
Sbjct: 272 FKIFEIVGTPN---IKSWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDVLREILR 328
Query: 354 WNPEARLTVEEALDHPFLQQ 373
+ PE RLT + AL H + Q
Sbjct: 329 YPPERRLTAKGALSHRYFLQ 348
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 157 bits (396), Expect = 4e-38
Identities = 124/356 (34%), Positives = 178/356 (49%), Gaps = 43/356 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS---IFTREILLKRAIRELKFMSY 129
Y +V+G GS+G V A K T E +AIKKV RE+ L R +
Sbjct: 70 YMAERVVGTGSFGIVFQA--KCLETGE-SVAIKKVLQDRRYKNRELQLMRPM-------- 118
Query: 130 FKGHRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVIH----SNVLFSEFHIKHFLY 184
H N++SL L E V L RV+ SN F++K + Y
Sbjct: 119 --DHPNVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTY 176
Query: 185 QILCGMKYIHSAD-VIHRDLKPGNILCS-ITGEIKICDFGLARGISPSFTVAGGISNHIT 242
QI G+ YIH+ V HRD+KP N+L +T ++K+CDFG A+ + G N
Sbjct: 177 QIFRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAK------VLVKGEPN--I 228
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+Y+ +R+YRAPELI Y+ S+D+W+ GC+LAE +P+F G +S+ Q++EI K+LG
Sbjct: 229 SYICSRYYRAPELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLG 288
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLT 361
TP + IR + Y F PQ K PW ++F EA+DL RL+ ++P R T
Sbjct: 289 TPTREEIRCMNPN--YTDFRF--PQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCT 344
Query: 362 VEEALDHPFLQQVRNPEAEPICPHGP-----FDFTYEKHLYSMERLRECLCDEVSK 412
EA HPF ++R P A P+G F+F E SME + + + V +
Sbjct: 345 ALEACAHPFFNELREPNAR--LPNGRPLPPLFNFKQELGGASMELINRLIPEHVRR 398
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 157 bits (396), Expect = 4e-38
Identities = 105/309 (33%), Positives = 162/309 (51%), Gaps = 28/309 (9%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFT--REILLKRAIRELKFMSY 129
RY L LG G+YGTVV K ++AIK++ + E + R ++ LK +S
Sbjct: 3 RYITLTQLGDGTYGTVVLGQRKDTGE---KVAIKRMKRKYYSWEEAMNLREVKSLKKLS- 58
Query: 130 FKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILC 188
H NIV L E++ E LY E + +L ++I + E +K L+Q+L
Sbjct: 59 ---HPNIVKL--KEVIREN--DTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLT 111
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS--PSFTVAGGISNHITNYVA 246
G+ ++H HRDLKP N+LCS IKI DFGLAR I P FT +YV+
Sbjct: 112 GLAFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRPPFT----------DYVS 161
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
TRWYRAPE++L Y ++D+WA+GCI+AE Y +P+F G+ + Q+ +I +LGTP +
Sbjct: 162 TRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDK 221
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
R + P K P + S +DL+E ++ ++P+ R T +++L
Sbjct: 222 --DDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSL 279
Query: 367 DHPFLQQVR 375
+P+ ++
Sbjct: 280 KYPYFHALK 288
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 155 bits (393), Expect = 9e-38
Identities = 105/312 (33%), Positives = 167/312 (52%), Gaps = 21/312 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE + +G+G+YG V A+ N +A+K++ ++ +RE+K + +
Sbjct: 277 YEKIDQIGEGTYGKVYKAI---NTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLR- 332
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI-HSNVLFSEFHIKHFLYQILCGMK 191
H+NIV L LEI+ E+ S +Y E +D+DL V+ +S + F+ +IKH QI +
Sbjct: 333 HKNIVRL--LEIMVEK--SSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALA 388
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
Y+H V+HRD+K NIL + G++K DFGLAR F + +N+ TN V T W+R
Sbjct: 389 YLHHRGVLHRDIKGSNILLNNNGDLKFADFGLAR-----FNTSSKSANY-TNRVITLWFR 442
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
PEL+L Y +VD+W+ GCI+ E + KP F G D + Q+ I ++GTP + +
Sbjct: 443 PPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPD---VHS 499
Query: 312 YGSSRCYDIFSTSKP-QYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ + + KP + KK+ + E F S A+DL ++L+ NP R + E L H
Sbjct: 500 WPEVKNLPWYELLKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHE 559
Query: 370 FLQQVRNPEAEP 381
+ +P EP
Sbjct: 560 YFTS-ESPPPEP 570
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 155 bits (391), Expect = 1e-37
Identities = 101/306 (33%), Positives = 159/306 (51%), Gaps = 15/306 (4%)
Query: 72 RYEILQVLGKGSYGTVVSAVDK-GNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYF 130
+YE + +G+G++G V A +K GN +A+KKV +E A+RE++ +
Sbjct: 49 KYEKVAKIGQGTFGEVFKAREKKGNKKF---VAMKKVLMDNEKEGFPITALREIRILQLL 105
Query: 131 KGHRNIVSLIDLEIVNEEPYSG----LYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQ 185
K H N+V+LI++ +G Y + ++DLA ++ + NV FS IK + Q
Sbjct: 106 K-HENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQ 164
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+ YIHS ++HRD+K N+L + G +K+ DFGLAR S + N TN V
Sbjct: 165 LLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNES---KNRYTNRV 221
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
T WYR PEL+L + Y VDMW GCI+AE + R P+ GN Q+ I ++ G+
Sbjct: 222 VTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFT 281
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSE-AVDLMERLIDWNPEARLTVEE 364
V Y K Q ++ + PY + DL+++L+ +P+ R+ +
Sbjct: 282 PDVWPGVEELELYKSIELPKNQKRRVKE-RLRPYVKDQTGCDLLDKLLTLDPKKRIDADT 340
Query: 365 ALDHPF 370
AL+H F
Sbjct: 341 ALNHDF 346
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 154 bits (389), Expect = 3e-37
Identities = 101/316 (31%), Positives = 162/316 (50%), Gaps = 27/316 (8%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE L+ +G+G+YG V A++KG +A+KK E + A+RE+ +
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKGTGK---LVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 132 GHRNIVSLIDLEIVNE------EPYSGLYCYQELVDYDLARVIHSNVL------FSEFHI 179
+V L+ +E V++ S LY E +D DL + I S F I
Sbjct: 60 TSIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLI 119
Query: 180 KHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEI-KICDFGLARGISPSFTVAGGIS 238
+ ++Q+ G+ + HS V+HRDLKP N+L E+ KI D GL R +FTV
Sbjct: 120 QKLMFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGR----AFTVP---L 172
Query: 239 NHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQ 298
T+ + T WYRAPE++L YS VDMW+VGCI AE R+ +F G+ Q++ I
Sbjct: 173 KSYTHEIVTLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIF 232
Query: 299 KILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEA 358
++LGTP + + R + ++ P+++ P S + VDL+ +++ +NP
Sbjct: 233 RLLGTPTEQQWPGVSTLRDWHVY----PKWEPQDLTLAVPSLSPQGVDLLTKMLKYNPAE 288
Query: 359 RLTVEEALDHPFLQQV 374
R++ + ALDHP+ +
Sbjct: 289 RISAKTALDHPYFDSL 304
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 153 bits (386), Expect = 6e-37
Identities = 101/307 (32%), Positives = 156/307 (49%), Gaps = 21/307 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y ++ +G+G+YG V K T +A+KK+ E + AIRE+ + +
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHK---TTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS---NVLFSEFHIKHFLYQILCG 189
H NIVSL D+ + + S LY E + DL + + S +K +LYQIL G
Sbjct: 60 HPNIVSLQDVLMQD----SRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQG 115
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+ + HS V+HRDLKP N+L G IK+ DFGLAR V T+ V T W
Sbjct: 116 IVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV-------YTHEVVTLW 168
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YR+PE++L RYS VD+W++G I AE +KP+F G+ + Q+ I + LGTP V
Sbjct: 169 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVW 228
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
S + Y + P++K +DL+ +++ ++P R++ + AL+HP
Sbjct: 229 PEVESLQDY---KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 285
Query: 370 FLQQVRN 376
+ + N
Sbjct: 286 YFNDLDN 292
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 152 bits (385), Expect = 7e-37
Identities = 101/300 (33%), Positives = 159/300 (52%), Gaps = 24/300 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y+ L+ LG+G+Y V KG ++ KV I E AIRE+ M +
Sbjct: 3 YQRLEKLGEGTYAHVY----KGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELR- 57
Query: 133 HRNIVSLID-LEIVNEEPYSGLYCYQELVDYDLARVIHS---NVLFSEFHIKHFLYQILC 188
H NI+SL D L+ N+ L E ++ DL + + + +K+F Q+L
Sbjct: 58 HPNIMSLSDVLQTENK-----LMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLK 112
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
G+ + H V+HRDLKP N+L + GE+K+ DFGLAR I G N +N V T
Sbjct: 113 GISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSI-------GIPVNTFSNEVVTL 165
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYRAP+++L + YS S+D+W+VGCI+AE +P+F G+++ Q+++I ++LGTP +
Sbjct: 166 WYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTE-- 223
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
+++ + + P YK +FP +DL+ R++ PE R T ++AL H
Sbjct: 224 -QSWPGISLLPEYKPTFPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQH 282
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 152 bits (385), Expect = 7e-37
Identities = 100/304 (32%), Positives = 169/304 (54%), Gaps = 21/304 (6%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE L ++G+GSYG V+ +K T + +AIKK +++ K A+RE+K + +
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKD--TGRI-VAIKKFLESDDDKMVKKIAMREIKLLKQLR 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHI-KHFLYQILCGM 190
H N+V+L LE+ ++ Y E VD+ + + ++ + + +L+QI+ G+
Sbjct: 60 -HENLVNL--LEVCKKK--KRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGI 114
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
+ HS ++IHRD+KP NIL S +G +K+CDFG AR ++ V T+YVATRWY
Sbjct: 115 GFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEV-------YTDYVATRWY 167
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
RAPEL++ +Y K+VD+WA+GC++ E + +P+F G+ + Q+ I LG ++ R
Sbjct: 168 RAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLG---NLIPR 224
Query: 311 TYGSSRCYDIFSTSK-PQYK-KTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
+F+ + P+ K + P +P S +DL ++ + +P+ R E L H
Sbjct: 225 HQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHH 284
Query: 369 PFLQ 372
F Q
Sbjct: 285 DFFQ 288
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 152 bits (385), Expect = 7e-37
Identities = 123/353 (34%), Positives = 178/353 (49%), Gaps = 37/353 (10%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +V+G GS+G V A K T E +AIKKV + REL+ M
Sbjct: 40 YMAERVVGTGSFGIVFQA--KCLETGET-VAIKKVLQD------RRYKNRELQLMRVMD- 89
Query: 133 HRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVIH----SNVLFSEFHIKHFLYQIL 187
H N+V L + L E V L RV+ +N ++K ++YQI
Sbjct: 90 HPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIF 149
Query: 188 CGMKYIHS-ADVIHRDLKPGNILCS-ITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
G+ YIH+ A V HRDLKP N+L +T ++KICDFG A+ + G +N +Y+
Sbjct: 150 RGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQL------VKGEAN--ISYI 201
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPELI Y+ S+D+W+ GC+LAE +P+F G +++ Q++EI K+LGTP
Sbjct: 202 CSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPT 261
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEE 364
+ IR Y F PQ K PW +IF EA+D RL+ ++P R T E
Sbjct: 262 REEIRCMNPH--YTDFRF--PQIKAHPWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALE 317
Query: 365 ALDHPFLQQVRNPEAEPICPHGP-----FDFTYEKHLYSMERLRECLCDEVSK 412
A HPF ++R P A P+G F+F E S E + + + D + +
Sbjct: 318 ACAHPFFDELREPNAR--LPNGRPFPPLFNFKQEVAGSSPELVNKLIPDHIKR 368
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 152 bits (385), Expect = 7e-37
Identities = 103/302 (34%), Positives = 165/302 (54%), Gaps = 22/302 (7%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+Y+ ++ +G+G+YGTV + T E+ +A+K+V E + A+RE+ + K
Sbjct: 3 KYDKMEKIGEGTYGTVFKG--RNRDTMEI-VALKRVRLDEDDEGVPSSALREICLLKELK 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGM 190
H+NIV LID+ +++ L E D DL + S N + F+ Q+L G+
Sbjct: 60 -HKNIVRLIDVLHSDKK----LTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGL 114
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
+ HS +V+HRDLKP N+L + GE+K+ DFGLAR G + V T WY
Sbjct: 115 AFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAF-------GIPVKCYSAEVVTLWY 167
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFY-GRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
R P+++ K Y+ S+DMW+ GCILAE +P+F G+D L Q+M+I ++LGTP +
Sbjct: 168 RPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNE--D 225
Query: 310 RTYGSSRCYDIFSTSKPQYKK-TPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
G S D + P + T W ++ P +S+ DL+++L+ P R++ E A+ H
Sbjct: 226 SWPGVSHLSDY--VALPSFPAITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQH 283
Query: 369 PF 370
P+
Sbjct: 284 PY 285
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 152 bits (384), Expect = 1e-36
Identities = 100/308 (32%), Positives = 162/308 (52%), Gaps = 20/308 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L+ +G+G+YG V A +K + +A+KK E + +RE+ +
Sbjct: 16 FEKLEKVGEGTYGKVYRAREKATG---MIVALKKTRLHEDEEGVPPTTLREISILRMLAR 72
Query: 133 HRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVIHS----NVLFSEFHIKHFLYQIL 187
+IV L+D++ +N+E + LY E VD DL + I S + +K +YQ+
Sbjct: 73 DPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQLC 132
Query: 188 CGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYVA 246
GM + H V+HRDLKP N+L T +KI D GLAR +FT+ T+ +
Sbjct: 133 KGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLAR----AFTLP---MKKYTHEIL 185
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
T WYRAPE++L YS VDMW+VGCI AE ++ +F G+ L Q++ I ++LGTP +
Sbjct: 186 TLWYRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNE 245
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
V G S+ D PQ+K P +DL+ +++++ P R++ ++A+
Sbjct: 246 EV--WPGVSKLKDWH--EYPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAM 301
Query: 367 DHPFLQQV 374
+HP+ +
Sbjct: 302 EHPYFDDL 309
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 152 bits (383), Expect = 1e-36
Identities = 104/315 (33%), Positives = 162/315 (51%), Gaps = 32/315 (10%)
Query: 79 LGKGSYGTVVSA----------VDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMS 128
LG+G+Y + V G +V +AIKK+ + AIRE+K +
Sbjct: 10 LGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEISAIREIKSLK 69
Query: 129 YFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI-HSNVLFSEFHIKHFLYQIL 187
+ +V LID + ++ ++ E V+ +L VI +S+ + IK ++ +L
Sbjct: 70 RIDS-KYVVRLIDTFVYDK----CVHIVLEYVETNLENVIRNSDKIIMPGDIKAWILMVL 124
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVAT 247
G+ H +IHRD+KP NIL + G +K+ DFGL RGI N +T T
Sbjct: 125 RGVYECHRLFIIHRDIKPNNILITSEGMVKLADFGLTRGIG----------NRMTPQAVT 174
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
RWYRAPEL++ + Y VDMW+VGC+ AE + R P+F G+ + Q+ I + LGTP
Sbjct: 175 RWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTP--- 231
Query: 308 VIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALD 367
V R + F + QY K +F ASS+A+DL+E+L+ NP R++ ++A+
Sbjct: 232 VEREWPGVSTLPEFLDFQ-QYPKASLNGLFSAASSDALDLLEKLLTLNPCNRISCDDAIK 290
Query: 368 HPFLQQVRNPEAEPI 382
HP+ + +P PI
Sbjct: 291 HPYFKS--SPPPTPI 303
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 152 bits (383), Expect = 1e-36
Identities = 103/311 (33%), Positives = 167/311 (53%), Gaps = 38/311 (12%)
Query: 72 RYEILQVLGKGSYGTVVSA--VDKGNPTHEVQLAIKKVTSIFT--REILLKRAIRELKFM 127
RY + + LG G++G V+ A +D G+ ++AIK++ F E + R ++ LK +
Sbjct: 44 RYLMTKRLGDGTFGEVMLAKKIDTGD-----RVAIKRMKKKFYSWEEAMSLREVKSLKKL 98
Query: 128 SYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQI 186
+ H NI+ L E++ E LY E + +L ++ + F E I++ +YQ+
Sbjct: 99 N----HPNIIKL--REVIRENDI--LYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQV 150
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGI--SPSFTVAGGISNHITNY 244
L G+ ++H HRD+KP NI+C+ T +KI DFGLAR I P +T +Y
Sbjct: 151 LQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYT----------DY 200
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V+TRWYRAPE++L Y+ +DMWA+GCI+AE Y +P+F G + Q+ +I ILGTP
Sbjct: 201 VSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTP 260
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKK---TPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
+ Y + S ++++ TP ++ S E + LM ++ WNPE R
Sbjct: 261 NK-----DEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPN 315
Query: 362 VEEALDHPFLQ 372
++L + + Q
Sbjct: 316 ANQSLRYKYFQ 326
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 152 bits (383), Expect = 1e-36
Identities = 95/262 (36%), Positives = 140/262 (53%), Gaps = 24/262 (9%)
Query: 114 EILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNV- 172
E + R ++ L+ M+ H NIV L E++ E LY E ++ +L +++
Sbjct: 10 ECINLREVKSLRRMN----HPNIVKL--KEVIRENDI--LYFVFEYMECNLYQLMKDRQK 61
Query: 173 LFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGI--SPS 230
LF+E IK++ +Q+ G+ Y+H HRDLKP N+L S IKI DFGLAR + SP
Sbjct: 62 LFAEADIKNWCFQVFQGLSYMHQRGYFHRDLKPENLLVS-KDIIKIADFGLAREVNSSPP 120
Query: 231 FTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDS 290
FT YV+TRWYRAPE++L Y+ VDMWA+G I+AE +P+F G
Sbjct: 121 FT----------EYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASE 170
Query: 291 LHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMER 350
++ +I ++GTP + + + PQ P + P AS +A++L+ER
Sbjct: 171 ADEIYKICSVIGTPTEET--WLEGLNLANTINYQFPQLPGVPLSSLMPSASEDAINLIER 228
Query: 351 LIDWNPEARLTVEEALDHPFLQ 372
L W+P +R T E L HPF Q
Sbjct: 229 LCSWDPSSRPTAAEVLQHPFFQ 250
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 151 bits (382), Expect = 2e-36
Identities = 103/342 (30%), Positives = 171/342 (49%), Gaps = 20/342 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE Q +G G++G V AV+ + ++AIKKV L +R +RE++ + Y
Sbjct: 82 YEPTQNIGSGAFGIVCEAVETSS---NQKVAIKKVAHASATPTLARRTLREIRVLRYIN- 137
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNV-LFSEFHIKHFLYQILCGMK 191
H NIV L D+ ++ +L+ +L +I+ N E +I FL Q+L G++
Sbjct: 138 HPNIVPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLE 197
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISN--HITNYVATRW 249
Y+H+A + HRDLKP N+L + G ++I DFG+A+ S + ++T +VAT
Sbjct: 198 YLHAACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHVATLP 257
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YRAPEL+ +S +VDMWAVGCI E R + G Q+ + +LG P Q VI
Sbjct: 258 YRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPPQEVI 317
Query: 310 RTYGSSR----CYDIFSTSKPQYKKTPWCEI-----FPYASSEAVDLMERLIDWNPEARL 360
R D + ++ +C+ + + +D +++L ++ + R+
Sbjct: 318 NEVRCDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVKQLFQYDAQKRI 377
Query: 361 TVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSMERL 402
+++AL HP++Q+V EA P F +K + +E L
Sbjct: 378 NIQDALLHPYIQRVIPAEA----PQKKCPFRVKKDMMQVEDL 415
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 151 bits (382), Expect = 2e-36
Identities = 103/316 (32%), Positives = 170/316 (53%), Gaps = 40/316 (12%)
Query: 77 QVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS---IFTREILLKRAIR-----ELKFMS 128
+V+G GS+G V A K + T+E+ +AIKKV RE+ + R + +LK+
Sbjct: 40 KVIGNGSFGVVFLA--KLSTTNEM-VAIKKVLQDKRFKNRELQIMRKLNHPNIVKLKYFF 96
Query: 129 YFKGHRN---IVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQ 185
Y G + ++LI LE V E Y Y + ++K ++YQ
Sbjct: 97 YSSGEKKDELYLNLI-LEYVPETVYRVARHYSK-----------QRQQIPMIYVKLYMYQ 144
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNY 244
+L + YIHS + HRD+KP N+L +G +K+CDFG A+ + + +Y
Sbjct: 145 LLRSLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRN--------EPNVSY 196
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
+ +R+YRAPELI Y+ S+D+W+ G ++AE +P+F G+ + Q++EI K+LGTP
Sbjct: 197 ICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTP 256
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVE 363
+ I++ + Y F PQ K PW ++F + +EA+DL+ ++I++ P +R T +
Sbjct: 257 TREQIQSMNPN--YKEFKF--PQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSRPTPQ 312
Query: 364 EALDHPFLQQVRNPEA 379
A H F ++RNP+A
Sbjct: 313 AACQHAFFDELRNPDA 328
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 151 bits (381), Expect = 2e-36
Identities = 106/321 (33%), Positives = 162/321 (50%), Gaps = 23/321 (7%)
Query: 57 TKRSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREIL 116
++R+ S F Y L+ LG+G+Y TV KG L K + E
Sbjct: 176 SRRASLSEIGFGKMETYIKLEKLGEGTYATVY----KGRSKLTENLVALKEIRLEHEEGA 231
Query: 117 LKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFS 175
AIRE+ + K H NIV+L D+ ++ L E +D DL + + + S
Sbjct: 232 PCTAIREVSLLKDLK-HANIVTLHDIVHTDKS----LTLVFEYLDKDLKQYMDDCGNIMS 286
Query: 176 EFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS-PSFTVA 234
++K FLYQIL G+ Y H V+HRDLKP N+L + GE+K+ DFGLAR S P+ T
Sbjct: 287 MHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKT-- 344
Query: 235 GGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQV 294
+N V T WYR P+++L Y +DMW VGCI E +P+F G+ ++
Sbjct: 345 ------YSNEVVTLWYRPPDVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDEL 398
Query: 295 MEIQKILGTPKQIVIRTY-GSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLID 353
I ++LGTP Q T+ G S + + + P+YK P P SE ++L+ + +
Sbjct: 399 HLIFRLLGTPSQ---ETWPGISSNEEFKNYNFPKYKPEPLINHAPRLDSEGIELIRKFLQ 455
Query: 354 WNPEARLTVEEALDHPFLQQV 374
+ + R++ EEA+ H + + +
Sbjct: 456 YESKKRVSAEEAMKHVYFRSL 476
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 151 bits (381), Expect = 2e-36
Identities = 110/332 (33%), Positives = 167/332 (50%), Gaps = 34/332 (10%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F++P RY L+ L G+ G VV A D ++AIKK+ F + +RA RE
Sbjct: 23 FTIPTRYVNLKFLNVGAQGIVVMADDLVTTQ---RVAIKKMQQPFLLTMSARRAYREFIL 79
Query: 127 MSYFKGHRNIVSLIDLEIVNEE--PYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
++ K H NI+ L++ + + +Y E + ++L VIH L E + +Y
Sbjct: 80 LTTLK-HPNIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLRLDHET-LSFLVY 137
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q LC +K++H+ IHRDLKP NI+ + +K+ DFGLAR + +++Y
Sbjct: 138 QSLCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLAR--------RRNVDMRMSDY 189
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
V TR+YRAPE+IL YS+ VD+W+VGCILAE +F G D Q +I +L TP
Sbjct: 190 VGTRYYRAPEVILG-LNYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTP 248
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYAS--------------SEAVDLMER 350
I ++ S PQ+ + EI P ++ A DL+
Sbjct: 249 DDHFINQLEPIGA--VYVRSLPQHLARAFNEIVPDSNFLPETENPKDHLTLHMARDLLFN 306
Query: 351 LIDWNPEARLTVEEALDHPFL--QQVRNPEAE 380
++ NPE R +VE+AL+HP+ +V P +E
Sbjct: 307 MLKINPEERYSVEDALNHPYTMDDEVNAPASE 338
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 151 bits (381), Expect = 2e-36
Identities = 104/316 (32%), Positives = 164/316 (50%), Gaps = 18/316 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y IL V+ +G+YG V K T EV +A+K+ +E A+RE+ +
Sbjct: 399 YVILNVIAEGTYGEVFRG--KNTRTDEV-VALKRFKMEKEKEGFPITALREINMLLKAGA 455
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS----NVLFSEFHIKHFLYQILC 188
H NIV++ EI+ + +Y E V++D+ +I N F K + Q+L
Sbjct: 456 HENIVNV--KEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLS 513
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
G++++H ++HRDLK N+L S +G +KI DFGLAR + + + +T V T
Sbjct: 514 GIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMK--LTPIVVTL 571
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYR+PEL+L K YS VDMW++GCI+AEF KP+F G+ +QV +I +++GTP + +
Sbjct: 572 WYRSPELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQI 631
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIF---PYASSEAVDLMERLIDWNPEARLTVEEA 365
+ +++ P K IF + DL+ ++ NP RLT EA
Sbjct: 632 WPDIKELKVWNM--VEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEA 689
Query: 366 LDHPFLQQVRNPEAEP 381
L H + + +P+A P
Sbjct: 690 LQHDWFSE--HPKAVP 703
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 151 bits (381), Expect = 2e-36
Identities = 96/308 (31%), Positives = 161/308 (52%), Gaps = 25/308 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L+ +G+G+YG V A K T E+ +A+KK+ RE AIRE+K +
Sbjct: 26 FEKLEQIGEGTYGQVYMA--KEIKTGEI-VALKKIRMDNEREGFPITAIREIKILKKLH- 81
Query: 133 HRNIVSLIDLEIV------------NEEPYSGLYCYQELVDYDLARVI-HSNVLFSEFHI 179
H N++ L ++ N + G+Y E +D+DL + + F+ I
Sbjct: 82 HENVIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQI 141
Query: 180 KHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISN 239
K ++ Q+L G+ Y H V+HRD+K N+L G +K+ DFGLAR S T
Sbjct: 142 KCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHT------G 195
Query: 240 HITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQK 299
++TN V T WYR PEL+L +Y ++DMW+VGCI AE KP+ G + Q+ +I +
Sbjct: 196 NLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFE 255
Query: 300 ILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEAR 359
+ G+P + + ++ F ++P ++ E F + A++L+E+++ +P R
Sbjct: 256 LCGSPDEKLWPGVSKMPWFNNFKPARPLKRRVR--EFFRHFDRHALELLEKMLVLDPAQR 313
Query: 360 LTVEEALD 367
++ ++ALD
Sbjct: 314 ISAKDALD 321
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 150 bits (380), Expect = 3e-36
Identities = 97/308 (31%), Positives = 159/308 (51%), Gaps = 25/308 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L+ +G+G+YG V A K T E+ +A+KK+ RE AIRE+K +
Sbjct: 26 FEKLEQIGEGTYGQVYMA--KEIKTGEI-VALKKIRMDNEREGFPITAIREIKILKKLH- 81
Query: 133 HRNIVSLIDLEIV------------NEEPYSGLYCYQELVDYDLARVI-HSNVLFSEFHI 179
H N++ L ++ N + G+Y E +D+DL + + F+ I
Sbjct: 82 HENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQI 141
Query: 180 KHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISN 239
K ++ Q+L G+ Y H V+HRD+K N+L G +K+ DFGLAR S T
Sbjct: 142 KCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHT------G 195
Query: 240 HITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQK 299
++TN V T WYR PEL+L +Y ++DMW+VGCI AE KP+ G Q+ +I +
Sbjct: 196 NLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYE 255
Query: 300 ILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEAR 359
+ G+P + Y+ +S+P ++ EI+ + A++L+E+++ +P R
Sbjct: 256 LCGSPDESNWPGVSKMPWYNQMKSSRPLKRRVR--EIYRHFDRHALELLEKMLVLDPSQR 313
Query: 360 LTVEEALD 367
+ ++ALD
Sbjct: 314 ICAKDALD 321
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 150 bits (379), Expect = 4e-36
Identities = 108/322 (33%), Positives = 161/322 (49%), Gaps = 42/322 (13%)
Query: 73 YEILQVLGKGSYGTVVSA--VDKGNPTHEVQLAIKKVTS---IFTREILLKRA-----IR 122
Y +V+G GS+G V A D G +AIKKV RE+ + R I
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGE-----LVAIKKVLQDKRFKNRELQIMRKLDHCNIV 110
Query: 123 ELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYC-YQELVDYDLAR-VIHSNVLFSEFHIK 180
L++ Y G + +E Y L Y Y +AR + ++K
Sbjct: 111 RLRYFFYSSGEKK-----------DEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVK 159
Query: 181 HFLYQILCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISN 239
++YQ+ + YIHS + HRD+KP N+L T +K+CDFG A+ + G N
Sbjct: 160 LYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL------VRGEPN 213
Query: 240 HITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQK 299
+Y+ +R+YRAPELI Y+ S+D+W+ GC+LAE +P+F G+ + Q++EI K
Sbjct: 214 --VSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
Query: 300 ILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEA 358
+LGTP + IR + Y F PQ K PW ++F P EA+ L RL+++ P A
Sbjct: 272 VLGTPTREQIREMNPN--YTEFKF--PQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTA 327
Query: 359 RLTVEEALDHPFLQQVRNPEAE 380
RLT EA H F ++R+P +
Sbjct: 328 RLTPLEACAHSFFDELRDPNVK 349
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 149 bits (377), Expect = 6e-36
Identities = 99/316 (31%), Positives = 172/316 (54%), Gaps = 23/316 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ + +G+G+YG V A + N T + +A+KK+ E + AIRE+ + K
Sbjct: 8 FQRAEKIGEGTYGIVYKA--RSNSTGQ-DVALKKIRLEGETEGVPSTAIREISLLKNLK- 63
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNV-LFSEFHIKHFLYQILCGMK 191
H N+V L D+ I + LY E ++ DL +++ +F+ IK +++QIL +
Sbjct: 64 HPNVVQLFDVVISG----NNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVG 119
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ H+ ++HRDLKP N+L G+IK+ DFGLAR + T+ V T WYR
Sbjct: 120 FCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRA-------YTHEVVTLWYR 172
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APE++L K YS VD+W++GCI +E R+ +F G+ + Q+ I + L TP +
Sbjct: 173 APEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDE--TNW 230
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
G ++ D F T P+++ T + P EA +L+ ++ ++P R++ ++AL H +
Sbjct: 231 PGVTQLPD-FKTKFPRWEGTNMPQ--PITEHEAHELIMSMLCYDPNLRISAKDALQHAYF 287
Query: 372 QQVRNPE--AEPICPH 385
+ V++ + A P+ P+
Sbjct: 288 RNVQHVDHVALPVDPN 303
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 149 bits (376), Expect = 8e-36
Identities = 91/306 (29%), Positives = 161/306 (51%), Gaps = 21/306 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y+ ++ +G+G+YG V A K + +A+KK+ E + AIRE+ +
Sbjct: 4 YQKVEKIGEGTYGVVYKARHKLSGRI---VAMKKIRLEDESEGVPSTAIREISLLKEVND 60
Query: 133 HRNIVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIH-----SNVLFSEFHIKHFLYQI 186
N + + L +I++ E S LY E +D DL + + ++ F YQ+
Sbjct: 61 ENNRSNCVRLLDILHAE--SKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQL 118
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVA 246
+ G+ + HS +IHRDLKP N+L G +K+ DFGLAR G + T+ +
Sbjct: 119 VNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSF-------GVPLRNYTHEIV 171
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
T WYRAPE++L + YS VD+W+VGCI AE R P+F G+ + ++ +I ++LGTP +
Sbjct: 172 TLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNE 231
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
V + + ++ P++K+ ++ P +A++L+ ++ ++P R++ + AL
Sbjct: 232 EV---WPGVTLLQDYKSTFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRAL 288
Query: 367 DHPFLQ 372
+L+
Sbjct: 289 QQNYLR 294
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 149 bits (375), Expect = 1e-35
Identities = 101/317 (31%), Positives = 160/317 (49%), Gaps = 19/317 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L +G+G+YG V A D T E+ +A+KKV ++ + ++RE+ + +
Sbjct: 39 FEKLNRIGEGTYGIVYRARD--TQTDEI-VALKKVRMDKEKDGIPISSLREITLLLRLR- 94
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILCGMK 191
H NIV L ++ + N ++ + DLA ++ + FSE +K + Q+L G++
Sbjct: 95 HPNIVELKEVVVGNH--LESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 152
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
Y+H +IHRDLK N+L + G +K DFGLAR G +T V T WYR
Sbjct: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAY-------GVPVKPMTPKVVTLWYR 205
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L + S+DMWAVGCILAE +P+ G +HQ+ I ++LGTP + +
Sbjct: 206 APELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPG 265
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
+ +S K Y FP+ S + L+ L ++P+ R T + L+ +
Sbjct: 266 FSKLPLVGQYSLRKQPYNNLK--HKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYF 323
Query: 372 QQVR---NPEAEPICPH 385
++ PE P PH
Sbjct: 324 KEKPLPCEPELMPTFPH 340
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 148 bits (374), Expect = 1e-35
Identities = 98/332 (29%), Positives = 165/332 (49%), Gaps = 32/332 (9%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS---IFTREILLKRAIRE---LKF 126
YE +VLG GS+G V+ A G P +A+K+V RE+ + RAI +K
Sbjct: 25 YEPCRVLGSGSFGVVIQAKLVGTPGF---IAVKRVLQDKRYKNRELQIMRAISHPNIIKL 81
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
+++F H L ++ E Y + + D D+ IK + +Q+
Sbjct: 82 IAFFHTHNPSKDETHLCLLLE------YMPETVFD-DMRWYTRRRKSIPNLSIKLYAFQL 134
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+ Y+HS V HRD+KP N+L TG +K+CDFG A+ + PS +Y+
Sbjct: 135 FRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPS--------EPNVSYI 186
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPEL+ Y+ +D+W+ C++AE + +P+F G+ S+ Q++EI ++LGTP
Sbjct: 187 CSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPS 246
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPY-ASSEAVDLMERLIDWNPEARLTVEE 364
I + + S P + + P+ + A+DL+ +++ + P R++ E
Sbjct: 247 YHEISVMNP----NYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIE 302
Query: 365 ALDHPFLQQVRNPEAEPICPHGPFDFTYEKHL 396
L HPF ++R+P C + T E+HL
Sbjct: 303 VLTHPFFDELRDPNCMYHCSRD--EGTIERHL 332
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 148 bits (373), Expect = 2e-35
Identities = 118/364 (32%), Positives = 177/364 (48%), Gaps = 28/364 (7%)
Query: 15 RQMPNVSRATKKLKKLLDPYVD-HMKQSY--ELDQNNHIYVDPILTK--RSIYSPANFSV 69
R P +T+ + K L D + + Y +L N+ I+ P+ + R S F
Sbjct: 102 RNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGK 161
Query: 70 PGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSY 129
Y L LG+G+Y TV KG L K + E AIRE+ +
Sbjct: 162 LETYIKLDKLGEGTYATVY----KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD 217
Query: 130 FKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILC 188
K H NIV+L D I++ E L E +D DL + + + + ++K FL+Q+L
Sbjct: 218 LK-HANIVTLHD--IIHTE--KSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLR 272
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS-PSFTVAGGISNHITNYVAT 247
G+ Y H V+HRDLKP N+L + GE+K+ DFGLAR S P+ T + N V T
Sbjct: 273 GLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYS--------NEVVT 324
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
WYR P+++L YS +DMW VGCI E +P+F G+ Q+ I +ILGTP +
Sbjct: 325 LWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTE- 383
Query: 308 VIRTYGSSRCYDIFST-SKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
T+ + F T + P+Y+ P S+ DL+ +L+ + R++ E+A+
Sbjct: 384 --ETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAM 441
Query: 367 DHPF 370
HPF
Sbjct: 442 KHPF 445
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 148 bits (373), Expect = 2e-35
Identities = 118/364 (32%), Positives = 177/364 (48%), Gaps = 28/364 (7%)
Query: 15 RQMPNVSRATKKLKKLLDPYVD-HMKQSY--ELDQNNHIYVDPILTK--RSIYSPANFSV 69
R P +T+ + K L D + + Y +L N+ I+ P+ + R S F
Sbjct: 54 RNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGK 113
Query: 70 PGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSY 129
Y L LG+G+Y TV KG L K + E AIRE+ +
Sbjct: 114 LETYIKLDKLGEGTYATVY----KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD 169
Query: 130 FKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILC 188
K H NIV+L D I++ E L E +D DL + + + + ++K FL+Q+L
Sbjct: 170 LK-HANIVTLHD--IIHTE--KSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLR 224
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS-PSFTVAGGISNHITNYVAT 247
G+ Y H V+HRDLKP N+L + GE+K+ DFGLAR S P+ T + N V T
Sbjct: 225 GLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYS--------NEVVT 276
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
WYR P+++L YS +DMW VGCI E +P+F G+ Q+ I +ILGTP +
Sbjct: 277 LWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTE- 335
Query: 308 VIRTYGSSRCYDIFST-SKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEAL 366
T+ + F T + P+Y+ P S+ DL+ +L+ + R++ E+A+
Sbjct: 336 --ETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAM 393
Query: 367 DHPF 370
HPF
Sbjct: 394 KHPF 397
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 147 bits (372), Expect = 2e-35
Identities = 112/312 (35%), Positives = 161/312 (50%), Gaps = 34/312 (10%)
Query: 78 VLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIV 137
V+G GS+G V A K T EV +AIKKV + REL+ M H N+V
Sbjct: 87 VVGTGSFGMVFQA--KCRETGEV-VAIKKVLQD------KRYKNRELQIMQMLD-HPNVV 136
Query: 138 SL---IDLEIVNEEPYSGLYCYQELVDYDLARVIHS----NVLFSEFHIKHFLYQILCGM 190
L NEE Y L E V + R S N L ++K + YQI G+
Sbjct: 137 CLKHSFYSRTENEEVYLNLVL--EFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGL 194
Query: 191 KYIHSA-DVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
Y+H+ + HRD+KP N+L + T ++KICDFG A+ + G N +Y+ +R
Sbjct: 195 AYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAK------VLVKGEPN--ISYICSR 246
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
+YRAPELI Y+ ++D+W+ GC++AE +P+F G + Q++EI K+LGTP +
Sbjct: 247 YYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE 306
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEEALD 367
I+ + Y F PQ K PW ++F EAVDL+ R ++P R T EA
Sbjct: 307 IKCMNPN--YTEFKF--PQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACI 362
Query: 368 HPFLQQVRNPEA 379
HPF ++R+P A
Sbjct: 363 HPFFDELRDPNA 374
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 147 bits (371), Expect = 3e-35
Identities = 122/358 (34%), Positives = 177/358 (49%), Gaps = 59/358 (16%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +V+G GS+G V A K T E Q+AIKKV + REL+ M +
Sbjct: 138 YMAQRVVGTGSFGVVFQA--KCLETGE-QVAIKKVLQD------KRYKNRELQIMR-LQD 187
Query: 133 HRNIVSL----------------IDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSE 176
H N+V L + LE V E Y Y ++ H ++F
Sbjct: 188 HPNVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQ-------HMPIIF-- 238
Query: 177 FHIKHFLYQILCGMKYIHSA-DVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVA 234
++ + YQI + Y+H V HRD+KP N+L + T ++KICDFG A+ + P
Sbjct: 239 --VQLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVP----- 291
Query: 235 GGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQV 294
G N +Y+ +R+YRAPELI Y+ ++DMW+ GC++AE +P+F G + Q+
Sbjct: 292 -GEPN--ISYICSRYYRAPELIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQL 348
Query: 295 MEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLID 353
+EI KILGTP + IR + Y F PQ K PW +IF EAVDL+ RL+
Sbjct: 349 VEIIKILGTPTREEIRCMNPN--YTEFKF--PQIKAHPWHKIFHKRMPPEAVDLVSRLLQ 404
Query: 354 WNPEARLTVEEALDHPFLQQVRNPEAEPICPHGP-----FDFTYEKHLYSMERLRECL 406
++P R T EA HPF +R+P P+G F+FT ++ + LR+ L
Sbjct: 405 YSPNLRCTALEACAHPFFDDLRDPNVS--LPNGRALPPLFNFTAQELAGASTELRQRL 460
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 147 bits (371), Expect = 3e-35
Identities = 110/368 (29%), Positives = 180/368 (48%), Gaps = 20/368 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L +G+G+Y V A D T ++ +A+KKV ++ RE+ +
Sbjct: 141 FEKLDKIGQGTYSIVYKARDL--ETGKI-VAMKKVRFANMDPESVRFMAREINILRKLD- 196
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARV-IHSNVLFSEFHIKHFLYQILCGMK 191
H N++ L L V + L+ E +++DL+ + + V F+E IK F+ Q+LCG++
Sbjct: 197 HPNVMKLQCL--VTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQIKCFMKQLLCGLE 254
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ HS ++HRD+K N+L + G +KI DFGLA P +T+ V T WYR
Sbjct: 255 HCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQ------DQPLTSRVVTLWYR 308
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L Y ++D+W+VGCILAE + KP+ G + Q+ +I K+ G+P +
Sbjct: 309 APELLLGSTEYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSE----E 364
Query: 312 YGSSRCYDIFSTSKPQYK-KTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
+ ++ + ++ KPQ+ K E F SS ++DL+++L+ PE R + L F
Sbjct: 365 FWNTTKFPQATSYKPQHPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEF 424
Query: 371 LQQVRNPEAEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFVSPPLMTP 430
P P P + + E R+ E K+ + + +TP
Sbjct: 425 FTTEPLPCHISSLPKYPPSKELDAKVRDEEAKRKKA--EAVKWRGHESVRRGLRDSKVTP 482
Query: 431 HFIAESNS 438
FIA NS
Sbjct: 483 EFIASGNS 490
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 146 bits (369), Expect = 5e-35
Identities = 100/310 (32%), Positives = 162/310 (52%), Gaps = 39/310 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E ++ +G+G+YG V + T ++ +A+KK+ E + AIRE+ + K
Sbjct: 4 FEKIEKIGEGTYGVVYKG--RNRLTGQI-VAMKKIRLESDDEGVPSTAIREISLLKELK- 59
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFH---IKHFLYQILCG 189
H NIV L D ++ EE + +Y E + DL + + S + ++ +LYQI
Sbjct: 60 HENIVCLED--VLMEE--NRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSA 115
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+ + H V+HRDLKP N+L +G IK+ DFGL R SF + I H + T W
Sbjct: 116 ILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGR----SFGIPVRIYTH---EIVTLW 168
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YRAPE++L RYS VD+W++GCI AE RKP+F G+ + Q+ + +IL TP +
Sbjct: 169 YRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTE--- 225
Query: 310 RTYGSSRCYDIFS--TSKPQYKKTPWC-------EIFPYASSEAVDLMERLIDWNPEARL 360
DI+ TS P YK T C + +DL+++++ ++P R+
Sbjct: 226 ---------DIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRI 276
Query: 361 TVEEALDHPF 370
+ ++ L+HP+
Sbjct: 277 SAKDILEHPY 286
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 146 bits (368), Expect = 7e-35
Identities = 104/322 (32%), Positives = 159/322 (49%), Gaps = 23/322 (7%)
Query: 56 LTKRSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREI 115
+++R+ S F Y L LG+G+Y TV KG L K + E
Sbjct: 125 MSRRASLSDIGFGKLETYVKLDKLGEGTYATVF----KGRSKLTENLVALKEIRLEHEEG 180
Query: 116 LLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI-HSNVLF 174
AIRE+ + K H NIV+L DL + L E +D DL + + H L
Sbjct: 181 APCTAIREVSLLKNLK-HANIVTLHDLIHTDRS----LTLVFEYLDSDLKQYLDHCGNLM 235
Query: 175 SEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS-PSFTV 233
S ++K F++Q+L G+ Y H ++HRDLKP N+L + GE+K+ DFGLAR S P+ T
Sbjct: 236 SMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKT- 294
Query: 234 AGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQ 293
+N V T WYR P+++L YS +DMW VGCI E +P+F G+ +
Sbjct: 295 -------YSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEE 347
Query: 294 VMEIQKILGTPKQIVIRTYGSSRCYDIFST-SKPQYKKTPWCEIFPYASSEAVDLMERLI 352
+ I ++LGTP + T+ + F T S P Y P P ++ + L+ L+
Sbjct: 348 LHLIFRLLGTPTE---ETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLL 404
Query: 353 DWNPEARLTVEEALDHPFLQQV 374
+ ++R++ E AL H + + +
Sbjct: 405 LYESKSRMSAEAALSHSYFRSL 426
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 146 bits (368), Expect = 7e-35
Identities = 95/310 (30%), Positives = 163/310 (51%), Gaps = 24/310 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L+ +G+G+YG V A +K T ++ +A+KK E + +RE+ +
Sbjct: 14 FEKLEKVGEGTYGKVYRAREKA--TGKI-VALKKTRLHEDEEGVPSTTLREISILRMLAR 70
Query: 133 HRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVIHS------NVLFSEFHIKHFLYQ 185
++V L+D++ +++E + LY E +D D+ + I S N+ IK +YQ
Sbjct: 71 DPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSFRSTGKNIPTQT--IKSLMYQ 128
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNY 244
+ GM + H ++HRDLKP N+L T +KI D GLAR +FT+ T+
Sbjct: 129 LCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLAR----AFTLP---MKKYTHE 181
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
+ T WYRAPE++L YS +VDMW+VGCI AE + +F G+ L Q++ I K+ GTP
Sbjct: 182 ILTLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTP 241
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+ + + + + + PQ+K + P VDL+ +++ + P R++ +
Sbjct: 242 NEEMWPGVSTLKNWHEY----PQWKPSTLSSAVPNLDEAGVDLLSKMLQYEPAKRISAKM 297
Query: 365 ALDHPFLQQV 374
A++HP+ +
Sbjct: 298 AMEHPYFDDL 307
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 145 bits (367), Expect = 9e-35
Identities = 96/317 (30%), Positives = 163/317 (51%), Gaps = 32/317 (10%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +V+G GS+G V+ H ++ K ++ K REL+ M K
Sbjct: 32 YTSSKVVGSGSFGVVMQV-------HLIESDSKAAIKRVLQDKRFKN--RELQIMRIMK- 81
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSE-------FHIKHFLYQ 185
H NIV LI + +Y ++++ + ++ L++ +K ++YQ
Sbjct: 82 HPNIVDLIAYYYTTGDNSDEVYL-NLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQ 140
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNY 244
+L + YIH++ + HRD+KP N+L G +K+CDFG A+ VAG + +Y
Sbjct: 141 LLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAK-----ILVAGEPN---VSY 192
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
+ +R+YRAPELI Y+ ++D+W+ GC++AE P+F G + Q++EI KILGTP
Sbjct: 193 ICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTP 252
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYA-SSEAVDLMERLIDWNPEARLTVE 363
+ I+T + F PQ + P +F + +A+DL+ +++ + P RLT
Sbjct: 253 SREQIKTMNPNYMEHRF----PQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAA 308
Query: 364 EALDHPFLQQVRNPEAE 380
EA+ HPF ++R+P +
Sbjct: 309 EAMCHPFFDELRDPNTK 325
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 145 bits (367), Expect = 9e-35
Identities = 116/324 (35%), Positives = 167/324 (50%), Gaps = 32/324 (9%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +V+G GS+G V A K T E +AIKKV + REL+ M
Sbjct: 73 YMAERVVGHGSFGVVFQA--KCLETGET-VAIKKVLQD------RRYKNRELQTMRLLD- 122
Query: 133 HRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVI-HSNVLFSEF---HIKHFLYQIL 187
H N+VSL E+ L E V + RVI H N L ++K + YQI
Sbjct: 123 HPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIF 182
Query: 188 CGMKYIHSA-DVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+ YIH V HRD+KP N+L + T ++K+CDFG A+ + G N +Y+
Sbjct: 183 RSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK------VLVKGEPN--ISYI 234
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPELI Y+ ++D+W+ GC+LAE +P+F G + Q++EI K+LGTP
Sbjct: 235 CSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPT 294
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEE 364
+ I+ + Y F PQ K PW +IF EAVDL+ RL+ ++P R +
Sbjct: 295 REEIKCMNPN--YTEFKF--PQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALD 350
Query: 365 ALDHPFLQQVRNPEAEPICPHGPF 388
+L HPF ++R+P A P+G F
Sbjct: 351 SLVHPFFDELRDPNAR--LPNGRF 372
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 145 bits (366), Expect = 1e-34
Identities = 99/314 (31%), Positives = 161/314 (50%), Gaps = 29/314 (9%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE + +G+GSYG V + T ++ +AIKK ++ K A+RE++ + K
Sbjct: 4 KYEKIGKIGEGSYGVVFKC--RNRDTGQI-VAIKKFLESEDDPVIKKIALREIRMLKQLK 60
Query: 132 GHRNIVSLID-------LEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
H N+V+L++ L +V E YC V ++L R E +K +
Sbjct: 61 -HPNLVNLLEVFRRKRRLHLVFE------YC-DHTVLHELDRYQRG---VPEHLVKSITW 109
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNY 244
Q L + + H + IHRD+KP NIL + IK+CDFG AR ++ G S++ T+Y
Sbjct: 110 QTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLT-------GPSDYYTDY 162
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
VATRWYR+PEL++ +Y VD+WA+GC+ AE P++ G + Q+ I+K LG
Sbjct: 163 VATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDL 222
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+ + +++ + P+ P FP S A+ L++ + +P RLT E+
Sbjct: 223 IPRHQQVFSTNQYFSGVKIPDPE-DMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQ 281
Query: 365 ALDHPFLQQVRNPE 378
L HP+ + +R E
Sbjct: 282 LLHHPYFENIREIE 295
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 145 bits (366), Expect = 1e-34
Identities = 98/315 (31%), Positives = 166/315 (52%), Gaps = 22/315 (6%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+Y+ L LG+GSYG V K T ++ +AIKK + K A+RE++ + K
Sbjct: 3 KYDRLSKLGEGSYGVVYKC--KNRDTGQI-VAIKKFVETEDDPHIKKIALREIRMLKQLK 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILCGM 190
H+N+V LI++ N + L+ EL D + + N ++ IK +YQ+L +
Sbjct: 60 -HQNLVGLIEVFKRNRK----LHLVFELCDRTVLHELEKNPHGVNDELIKKIIYQLLEAL 114
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
K+ HS IHRD+KP NI + ++K+ DFG AR I+ + T+YVATRWY
Sbjct: 115 KFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINTT--------EMYTDYVATRWY 166
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
R+PEL++ +Y VD+WAVGC+ AE + ++ G + Q+ I+K LG I
Sbjct: 167 RSPELLVGDVQYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLGEFLPRHIS 226
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH-- 368
+ +++ + S +P++ + P P ASS +D +++ + +P+ R + E + H
Sbjct: 227 IFRTNQFFFGLSIPEPEHLE-PLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGI 285
Query: 369 --PFLQQVRNPEAEP 381
++ ++R E+ P
Sbjct: 286 FSNWILRIRQDESTP 300
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 145 bits (366), Expect = 1e-34
Identities = 98/307 (31%), Positives = 162/307 (51%), Gaps = 26/307 (8%)
Query: 73 YEILQVLGKGSYGTV--VSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYF 130
++I Q LGKG+YG V V ++ G A+K++ E + + +RE+ M +
Sbjct: 38 FQIHQALGKGAYGNVYRVRSLHDGK-----DYALKQIMISSKNEGIPQSVLREITVMKHL 92
Query: 131 --KGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQ 185
K H NI+SL + ++ + E D+DL + + E KH Q
Sbjct: 93 ARKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQ 152
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
I+ + ++H+ +IHRDLKP NIL + +K+ DFGL++ S + T V
Sbjct: 153 IVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTA--------FTTLV 204
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
T WYR+PE++L Y+ +VDMWA+GCI++E Y R+P+F+G + Q+ +I K +GTP
Sbjct: 205 VTLWYRSPEVLLQ-SYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTP- 262
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEA 365
V + + S I S PQY+ T ++ P S +A++ +++ + ++ RL+ A
Sbjct: 263 --VGKDWPSESV--IARDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGA 318
Query: 366 LDHPFLQ 372
L HPFL+
Sbjct: 319 LSHPFLK 325
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 145 bits (365), Expect = 2e-34
Identities = 94/285 (32%), Positives = 153/285 (52%), Gaps = 41/285 (14%)
Query: 158 ELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIK 217
EL+D +L +VI + + + LYQ+LCG+K++HSA +IHRDLKP NI+ +K
Sbjct: 2 ELMDANLCQVIQMEL--DHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLK 59
Query: 218 ICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAE 277
I DFGLAR SF +T YV TR+YRAPE+IL Y ++VD+W+VGCI+ E
Sbjct: 60 ILDFGLARTAGTSFM--------MTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGE 110
Query: 278 FYGRKPVFMGNDSLHQVMEIQKILGTP-------KQIVIRTYGSSRCYDIFSTSKPQYKK 330
K +F G D + Q ++ + LGTP Q +R Y +R P+Y
Sbjct: 111 MVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENR---------PKYAG 161
Query: 331 TPWCEIFP------------YASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPE 378
+ ++FP +S+A DL+ +++ +P R++V++AL HP++ +P
Sbjct: 162 LTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA 221
Query: 379 AEPICPHGPFDFTYEKHLYSMERLRECLCDEVSKFHNDRQTKDFV 423
P +D ++ +++E +E + EV +++ +TK+ V
Sbjct: 222 EVEAPPPQIYDKQLDEREHTIEEWKELIYKEV--MNSEEKTKNGV 264
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 145 bits (365), Expect = 2e-34
Identities = 96/302 (31%), Positives = 155/302 (50%), Gaps = 16/302 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L +G+G+YG V A D T E+ +A+KKV ++ + ++RE+ + +
Sbjct: 10 FEKLNRIGEGTYGIVYRARD--TQTDEI-VALKKVRMDKEKDGIPISSLREITLLLRLR- 65
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILCGMK 191
H NIV L ++ + N ++ + DLA ++ + FSE +K + Q+L G++
Sbjct: 66 HPNIVELKEVVVGNH--LESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQ 123
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
Y+H +IHRDLK N+L + G +K DFGLAR G +T V T WYR
Sbjct: 124 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAY-------GVPVKPMTPKVVTLWYR 176
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L + S+DMWAVGCILAE +P+ G +HQ+ I ++LGTP + +
Sbjct: 177 APELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPG 236
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
+ +S K Y FP+ S + L+ L ++P+ R T + L+ +
Sbjct: 237 FSKLPLVGQYSLRKQPYNNLK--HKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYF 294
Query: 372 QQ 373
++
Sbjct: 295 KE 296
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 145 bits (365), Expect = 2e-34
Identities = 99/316 (31%), Positives = 159/316 (49%), Gaps = 15/316 (4%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 475
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 476 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T+WYR
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTQWYR 586
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F GN + Q+ ++ K LGTP + +
Sbjct: 587 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 646
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
Y + S+ Y S + DLM + + + P R++ E+ L H +
Sbjct: 647 YSELPVVKKMTFSEHPYNNLR-KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 705
Query: 372 QQVRNPEAEPICPHGP 387
++ P + P P
Sbjct: 706 RETPLPIDPSMFPTWP 721
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 145 bits (365), Expect = 2e-34
Identities = 99/316 (31%), Positives = 159/316 (49%), Gaps = 15/316 (4%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 423 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 478
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 479 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T+WYR
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTQWYR 589
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F GN + Q+ ++ K LGTP + +
Sbjct: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 649
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
Y + S+ Y S + DLM + + + P R++ E+ L H +
Sbjct: 650 YSELPVVKKMTFSEHPYNNLR-KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
Query: 372 QQVRNPEAEPICPHGP 387
++ P + P P
Sbjct: 709 RETPLPIDPSMFPTWP 724
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 145 bits (365), Expect = 2e-34
Identities = 99/316 (31%), Positives = 159/316 (49%), Gaps = 15/316 (4%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 410 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 465
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 466 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 523
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T+WYR
Sbjct: 524 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTQWYR 576
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F GN + Q+ ++ K LGTP + +
Sbjct: 577 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 636
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
Y + S+ Y S + DLM + + + P R++ E+ L H +
Sbjct: 637 YSELPVVKKMTFSEHPYNNLR-KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 695
Query: 372 QQVRNPEAEPICPHGP 387
++ P + P P
Sbjct: 696 RETPLPIDPSMFPTWP 711
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 145 bits (365), Expect = 2e-34
Identities = 99/316 (31%), Positives = 159/316 (49%), Gaps = 15/316 (4%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 419 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 474
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 475 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 532
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T+WYR
Sbjct: 533 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTQWYR 585
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F GN + Q+ ++ K LGTP + +
Sbjct: 586 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 645
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
Y + S+ Y S + DLM + + + P R++ E+ L H +
Sbjct: 646 YSELPVVKKMTFSEHPYNNLR-KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 704
Query: 372 QQVRNPEAEPICPHGP 387
++ P + P P
Sbjct: 705 RETPLPIDPSMFPTWP 720
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 145 bits (365), Expect = 2e-34
Identities = 99/316 (31%), Positives = 159/316 (49%), Gaps = 15/316 (4%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 40 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 95
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 96 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 153
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T+WYR
Sbjct: 154 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTQWYR 206
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F GN + Q+ ++ K LGTP + +
Sbjct: 207 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 266
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
Y + S+ Y S + DLM + + + P R++ E+ L H +
Sbjct: 267 YSELPVVKKMTFSEHPYNNLR-KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 325
Query: 372 QQVRNPEAEPICPHGP 387
++ P + P P
Sbjct: 326 RETPLPIDPSMFPTWP 341
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 145 bits (365), Expect = 2e-34
Identities = 116/324 (35%), Positives = 166/324 (50%), Gaps = 32/324 (9%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +V+G GS+G V A K T E +AIKKV + REL+ M
Sbjct: 69 YMAERVVGHGSFGVVFQA--KCLETGET-VAIKKVLQD------RRYKNRELQTMRLLD- 118
Query: 133 HRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVI-HSNVLFSEF---HIKHFLYQIL 187
H N+VSL E+ L E V + RVI H N L ++K + YQI
Sbjct: 119 HPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIF 178
Query: 188 CGMKYIHSA-DVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+ YIH V HRD+KP N+L + T ++K+CDFG A+ + G N +Y+
Sbjct: 179 RALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK------VLVKGEPN--ISYI 230
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPELI Y+ ++D+W+ GC+LAE +P+F G + Q++EI K+LGTP
Sbjct: 231 CSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPT 290
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEE 364
+ I+ + Y F PQ K PW +IF EAVDL+ RL+ ++P R +
Sbjct: 291 REEIKCMNPN--YTEFKF--PQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRSAALD 346
Query: 365 ALDHPFLQQVRNPEAEPICPHGPF 388
L HPF ++R+P A P+G F
Sbjct: 347 TLVHPFFDELRDPNAR--LPNGRF 368
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 144 bits (364), Expect = 2e-34
Identities = 106/335 (31%), Positives = 167/335 (49%), Gaps = 45/335 (13%)
Query: 79 LGKGSYGTVVSAV---DKGNPTHEVQLAIKKV---TSIFTREILLKRAIRELKFMSYFKG 132
+G+G++GTVV A DK N AIKKV T +RE+ + R
Sbjct: 41 IGRGAFGTVVQAYLTQDKKNWLGP--FAIKKVPAHTEYKSRELQILR----------IAD 88
Query: 133 HRNIVSL----IDLEIVNEEPYSGLY--CYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
H NIV L L + + Y L C E + ++ R + + + HI+ + YQI
Sbjct: 89 HPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQI 148
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
GM Y+H V HRD+KP N+L TG +KICDFG A+ + + +Y+
Sbjct: 149 ARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHN--------QPSISYI 200
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPELI+ +Y+ +D+W +GC++ E K +F G + L Q+ EI K+LG P
Sbjct: 201 CSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPD 260
Query: 306 QIVIRTYGSSRCYDIFSTSKPQY---KKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
+ I + S+ YD SKP + + + + F ++ + +DL+ +++ + P+ RL+
Sbjct: 261 KRFI--FFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSP 318
Query: 363 EEALDHPFLQQVRNPE-------AEPICPHGPFDF 390
L H F ++RN + EPI FDF
Sbjct: 319 RRILAHQFFNELRNDDTFLPRGFTEPIKLPNLFDF 353
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 144 bits (364), Expect = 2e-34
Identities = 100/316 (31%), Positives = 154/316 (48%), Gaps = 42/316 (13%)
Query: 76 LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRN 135
L+ +G+G+YG V ++ +A+KK+ E + A+RE+ + + H N
Sbjct: 25 LEKIGEGTYGVVYKGKNRRT---NAMVAMKKIRLESEDEGVPSTAVREISLLKELQ-HPN 80
Query: 136 IVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS---NVLFSEFHIKHFLYQILCGMKY 192
+V L + I+ E + L+ E + +DL R + + +K + +QIL M +
Sbjct: 81 VVGL-EAVIMQE---NRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCF 136
Query: 193 IHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRA 252
H VIHRDLKP N+L G IK+ DFGLAR I V T+ V T WYRA
Sbjct: 137 CHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRV-------YTHEVVTLWYRA 189
Query: 253 PELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTY 312
PE+++ +RYS VDMW++GCI AE +KP+F G+ + ++ I ++LGTP ++
Sbjct: 190 PEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGV 249
Query: 313 GSSRCYDIFSTSKPQYKKT--PWCEIF------------PYASSEAVDLMERLIDWNPEA 358
S P YK T W E F A L+E L+ ++P
Sbjct: 250 ----------ESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSL 299
Query: 359 RLTVEEALDHPFLQQV 374
RL ++AL HP+ +
Sbjct: 300 RLNAKKALVHPYFDNM 315
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 144 bits (363), Expect = 3e-34
Identities = 99/316 (31%), Positives = 158/316 (49%), Gaps = 15/316 (4%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ E ++RE+ + +
Sbjct: 418 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKENEGFPITSLREINTILKAQ- 473
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 474 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 531
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T+WYR
Sbjct: 532 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTQWYR 584
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F GN + Q+ ++ K LGTP + +
Sbjct: 585 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 644
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
Y + S+ Y S + DLM + + + P R++ E+ L H +
Sbjct: 645 YSELPVVKKMTFSEHPYNNLR-KRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYF 703
Query: 372 QQVRNPEAEPICPHGP 387
++ P + P P
Sbjct: 704 RETPLPIDPSMFPTWP 719
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 144 bits (363), Expect = 3e-34
Identities = 99/316 (31%), Positives = 158/316 (49%), Gaps = 15/316 (4%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ E ++RE+ + +
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKENEGFPITSLREINTILKAQ- 475
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 476 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T+WYR
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTQWYR 586
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F GN + Q+ ++ K LGTP + +
Sbjct: 587 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG 646
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
Y + S+ Y S + DLM + + + P R++ E+ L H +
Sbjct: 647 YSELPVVKKMTFSEHPYNNLR-KRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYF 705
Query: 372 QQVRNPEAEPICPHGP 387
++ P + P P
Sbjct: 706 RETPLPIDPSMFPTWP 721
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 144 bits (363), Expect = 3e-34
Identities = 98/312 (31%), Positives = 162/312 (51%), Gaps = 26/312 (8%)
Query: 68 SVPGRYEILQVLGKGSYGTV--VSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELK 125
+ P + Q LGKG+YG V V ++ G A+K++ E + + +RE+
Sbjct: 97 ATPSLTFLFQALGKGAYGNVYRVRSLHDGK-----DYALKQIMISSKNEGIPQSVLREIT 151
Query: 126 FMSYF--KGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIK 180
M + K H NI+SL + ++ + E D+DL + + E K
Sbjct: 152 VMKHLARKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAK 211
Query: 181 HFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNH 240
H QI+ + ++H+ +IHRDLKP NIL + +K+ DFGL++ S +
Sbjct: 212 HVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTA-------- 263
Query: 241 ITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKI 300
T V T WYR+PE++L Y+ +VDMWA+GCI++E Y R+P+F+G + Q+ +I K
Sbjct: 264 FTTLVVTLWYRSPEVLLQ-SYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKK 322
Query: 301 LGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARL 360
+GTP V + + S I S PQY+ T ++ P S +A++ +++ + ++ RL
Sbjct: 323 MGTP---VGKDWPSESV--IARDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRL 377
Query: 361 TVEEALDHPFLQ 372
+ AL HPFL+
Sbjct: 378 SARGALSHPFLK 389
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 144 bits (362), Expect = 3e-34
Identities = 98/314 (31%), Positives = 163/314 (51%), Gaps = 24/314 (7%)
Query: 68 SVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFM 127
S +++ L+ LG G+Y TV ++K T V +A+K+V + + E AIRE+ M
Sbjct: 2 SSSSQFKQLEKLGNGTYATVYKGLNK---TTGVYVALKEV-KLDSEEGTPSTAIREISLM 57
Query: 128 SYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFH------IKH 181
K H NIV L D +++ E + L E +D DL + + S + + +K+
Sbjct: 58 KELK-HENIVRLYD--VIHTE--NKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKY 112
Query: 182 FLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHI 241
F +Q+L G+ + H ++HRDLKP N+L + G++K+ DFGLAR G N
Sbjct: 113 FQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAF-------GIPVNTF 165
Query: 242 TNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKIL 301
++ V T WYRAP++++ + YS S+D+W+ GCILAE KP+F G + Q+ I I+
Sbjct: 166 SSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIM 225
Query: 302 GTPKQIVIRTYGSSRCYDIFSTSKP--QYKKTPWCEIFPYASSEAVDLMERLIDWNPEAR 359
GTP + + + Y+ +P ++ +D + L+ NP+ R
Sbjct: 226 GTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMR 285
Query: 360 LTVEEALDHPFLQQ 373
L+ ++AL HP+ +
Sbjct: 286 LSAKQALHHPWFAE 299
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 143 bits (361), Expect = 4e-34
Identities = 104/301 (34%), Positives = 153/301 (50%), Gaps = 20/301 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L +G+G+Y V A D + +A+KKV ++ RE++ +
Sbjct: 134 FEKLDKIGQGTYSNVYRARDLDQ---KKIVALKKVRFDNLEPESVRFMAREIQILRRLD- 189
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI-HSNVLFSEFHIKHFLYQILCGMK 191
H NI+ L L V LY E +++DLA + H + FSE +K +L Q+L G+
Sbjct: 190 HPNIIKLEGL--VTSRMSCSLYLVFEYMEHDLAGLASHPAIKFSESQVKCYLQQLLHGLD 247
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ HS V+HRD+K N+L +G +KI DFGLA P T +T+ V T WYR
Sbjct: 248 HCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQT------QPLTSRVVTLWYR 301
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
PEL+L RY +VD+W+ GCILAE Y KP+ G + Q+ +I K+ G+P +
Sbjct: 302 PPELLLGATRYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTE---DY 358
Query: 312 YGSSRC--YDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ SR IF ++P YK+ E F A+ L+E L+ NP+ R T AL
Sbjct: 359 WVKSRLPHATIFKPTQP-YKRLVG-ETFKEFPQPALALLETLLSVNPDDRGTATAALKSE 416
Query: 370 F 370
F
Sbjct: 417 F 417
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 143 bits (361), Expect = 4e-34
Identities = 111/310 (35%), Positives = 160/310 (50%), Gaps = 34/310 (10%)
Query: 78 VLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIV 137
V+G GS+G V A K T EV +AIKKV + REL+ M H N V
Sbjct: 88 VVGTGSFGMVFQA--KCRETGEV-VAIKKVLQD------KRYKNRELQIMQMLD-HPNAV 137
Query: 138 SL---IDLEIVNEEPYSGLYCYQELVDYDLARVIHS----NVLFSEFHIKHFLYQILCGM 190
+L NEE Y L E V + RV S N L ++K + YQI +
Sbjct: 138 ALKHSFFSRTDNEEVYLNLVL--EFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRAL 195
Query: 191 KYIHSA-DVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
YIH++ + HRD+KP N+L + T ++KICDFG A+ + G N +Y+ +R
Sbjct: 196 AYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAK------VLVKGEPN--VSYICSR 247
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
+YRAPELI Y+ ++D+W+ GC++AE +P+F G + Q++EI K+LGTP +
Sbjct: 248 YYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE 307
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEEALD 367
I+ + Y F PQ K PW ++F EAVDL+ R ++P R T EA
Sbjct: 308 IKCMNPN--YTEFKF--PQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTALEACI 363
Query: 368 HPFLQQVRNP 377
HP ++R+P
Sbjct: 364 HPLFDELRDP 373
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 143 bits (361), Expect = 4e-34
Identities = 96/301 (31%), Positives = 154/301 (50%), Gaps = 16/301 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L+ +G+G+Y +V A D H +A+KKV +K RE+ M
Sbjct: 213 FEKLEKIGQGTYSSVYRARDL---LHNKIVALKKVRFDLNDMESVKFMAREIIVMRRLD- 268
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIH-SNVLFSEFHIKHFLYQILCGMK 191
H N++ L L + S LY E +D+DL + V F+E +K ++ Q+L G++
Sbjct: 269 HPNVLKLEGL--ITAPVSSSLYLVFEYMDHDLLGLSSLPGVKFTEPQVKCYMRQLLSGLE 326
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ HS V+HRD+K N+L G +KI DFGLA P+ +V+ +T++V T WYR
Sbjct: 327 HCHSRGVLHRDIKGSNLLIDSKGVLKIADFGLATFFDPAKSVS------LTSHVVTLWYR 380
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
PEL+L Y VD+W+ GCIL E Y KP+ G + Q+ +I K+ G+P + R
Sbjct: 381 PPELLLGASHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPTENYWRK 440
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
F T+ P +K E+F + + L+E L+ +P+ R + + AL+ +
Sbjct: 441 QKLPSSAG-FKTAIPYRRKV--SEMFKDFPASVLSLLETLLSIDPDHRSSADRALESEYF 497
Query: 372 Q 372
+
Sbjct: 498 K 498
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 143 bits (360), Expect = 6e-34
Identities = 107/311 (34%), Positives = 162/311 (51%), Gaps = 30/311 (9%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y ++V+G GS+G V A + T E+ +AIKKV ++ K REL+ M
Sbjct: 119 YTDIKVIGNGSFGVVYQA--RLAETREL-VAIKKVL----QDKRFKN--RELQIMRKLD- 168
Query: 133 HRNIVSLIDLEIVNEEPYSGLYC-----YQELVDYDLAR-VIHSNVLFSEFHIKHFLYQI 186
H NIV L + E LY Y Y +AR + + ++K ++YQ+
Sbjct: 169 HCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQL 228
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+ YIHS V HRD+KP N+L T +K+CDFG A+ + G N +Y+
Sbjct: 229 FRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL------VRGEPN--VSYI 280
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPELI Y+ S+D+W+ GC+LAE +P+F G+ + Q++EI K+LGTP
Sbjct: 281 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 340
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYAS-SEAVDLMERLIDWNPEARLTVEE 364
+ IR + Y F PQ K PW ++F + EA+ L L+++ P +RL+ E
Sbjct: 341 REQIREMNPN--YTEFKF--PQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLE 396
Query: 365 ALDHPFLQQVR 375
A H F ++R
Sbjct: 397 ACAHSFFDELR 407
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 143 bits (360), Expect = 6e-34
Identities = 107/311 (34%), Positives = 162/311 (51%), Gaps = 30/311 (9%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y ++V+G GS+G V A + T E+ +AIKKV ++ K REL+ M
Sbjct: 119 YTDIKVIGNGSFGVVYQA--RLAETREL-VAIKKVL----QDKRFKN--RELQIMRKLD- 168
Query: 133 HRNIVSLIDLEIVNEEPYSGLYC-----YQELVDYDLAR-VIHSNVLFSEFHIKHFLYQI 186
H NIV L + E LY Y Y +AR + + ++K ++YQ+
Sbjct: 169 HCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQL 228
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+ YIHS V HRD+KP N+L T +K+CDFG A+ + G N +Y+
Sbjct: 229 FRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL------VRGEPN--VSYI 280
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPELI Y+ S+D+W+ GC+LAE +P+F G+ + Q++EI K+LGTP
Sbjct: 281 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 340
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYAS-SEAVDLMERLIDWNPEARLTVEE 364
+ IR + Y F PQ K PW ++F + EA+ L L+++ P +RL+ E
Sbjct: 341 REQIREMNPN--YTEFKF--PQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLE 396
Query: 365 ALDHPFLQQVR 375
A H F ++R
Sbjct: 397 ACAHSFFDELR 407
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 143 bits (360), Expect = 6e-34
Identities = 109/344 (31%), Positives = 165/344 (47%), Gaps = 30/344 (8%)
Query: 35 VDHMKQSYELDQNNHIYVDPILTK--RSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVD 92
VD + ++ LDQ P+ K R+ S F YE L LG+G+Y TV
Sbjct: 328 VDKLNRTPTLDQ-------PLTRKNRRASLSEIGFGKLETYEKLDKLGEGTYATVF---- 376
Query: 93 KGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSG 152
+G + K + E AIRE+ + + H N+V+L D I++ +
Sbjct: 377 RGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLR-HANVVTLHD--IIHTDRLLT 433
Query: 153 LYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCS 211
L E VD DL + + S N +I+ FLYQ+L G+ Y H V+HRDLKP N+L +
Sbjct: 434 LVF--EYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLIT 491
Query: 212 ITGEIKICDFGLARGIS-PSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWA 270
GE+K+ DFGLAR S P+ T +N V T WYR P+++L YS +DMW
Sbjct: 492 AKGELKLADFGLARAKSVPTKT--------YSNEVVTLWYRPPDVLLGSTDYSTHIDMWG 543
Query: 271 VGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKK 330
VGCIL E + +F G Q+ I + LG+P+ T + + + Y
Sbjct: 544 VGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTF--YPYANRHYNP 601
Query: 331 TPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQV 374
P C P + +L+ + + + + R++ EA+ HPFL+ +
Sbjct: 602 DPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFLRTI 645
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 143 bits (360), Expect = 6e-34
Identities = 109/344 (31%), Positives = 165/344 (47%), Gaps = 30/344 (8%)
Query: 35 VDHMKQSYELDQNNHIYVDPILTK--RSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVD 92
VD + ++ LDQ P+ K R+ S F YE L LG+G+Y TV
Sbjct: 205 VDKLNRTPTLDQ-------PLTRKNRRASLSEIGFGKLETYEKLDKLGEGTYATVF---- 253
Query: 93 KGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSG 152
+G + K + E AIRE+ + + H N+V+L D I++ +
Sbjct: 254 RGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLR-HANVVTLHD--IIHTDRLLT 310
Query: 153 LYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCS 211
L E VD DL + + S N +I+ FLYQ+L G+ Y H V+HRDLKP N+L +
Sbjct: 311 LVF--EYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLIT 368
Query: 212 ITGEIKICDFGLARGIS-PSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWA 270
GE+K+ DFGLAR S P+ T +N V T WYR P+++L YS +DMW
Sbjct: 369 AKGELKLADFGLARAKSVPTKT--------YSNEVVTLWYRPPDVLLGSTDYSTHIDMWG 420
Query: 271 VGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKK 330
VGCIL E + +F G Q+ I + LG+P+ T + + + Y
Sbjct: 421 VGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTF--YPYANRHYNP 478
Query: 331 TPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQV 374
P C P + +L+ + + + + R++ EA+ HPFL+ +
Sbjct: 479 DPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFLRTI 522
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 143 bits (360), Expect = 6e-34
Identities = 94/303 (31%), Positives = 152/303 (50%), Gaps = 21/303 (6%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RYE L LG+GSYG V D+ +A+K+ + K A+RE++ + K
Sbjct: 3 RYEKLSRLGEGSYGVVYKCRDRETGA---LVAVKRFVESEDDPAIRKIALREIRLLKNLK 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHI-KHFLYQILCGM 190
H N+VSL LE+ + L+ E + + + + H+ K YQ L G+
Sbjct: 60 -HPNLVSL--LEVFRRK--RRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGV 114
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
Y H +HRD+KP NIL + G++K+CDFG AR +SP + T+YVATRWY
Sbjct: 115 AYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPG--------ENYTDYVATRWY 166
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
RAPEL++ +Y VD+WA+GC+ AE + ++ G + Q+ I+K LG I+
Sbjct: 167 RAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQ 226
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSE---AVDLMERLIDWNPEARLTVEEALD 367
+G + + + P + P + P S + +D +++ +D +P R + E+
Sbjct: 227 IFGQNEYFKGITLPVPPTLE-PLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTK 285
Query: 368 HPF 370
H +
Sbjct: 286 HSY 288
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 142 bits (359), Expect = 8e-34
Identities = 109/343 (31%), Positives = 175/343 (50%), Gaps = 42/343 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS---IFTREILLKRAIR-----EL 124
Y +V+G GS+G V A K T E+ +AIKKV RE+ + R + +L
Sbjct: 548 YTDTKVIGNGSFGVVFQA--KLCDTGEL-VAIKKVLQDRRFKNRELQIMRKLEHCNIVKL 604
Query: 125 KFMSYFKGHRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
+ Y G + ++L E + E Y Y + + I N I+ +
Sbjct: 605 LYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKT-----KQTIPINF------IRLY 653
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHI 241
+YQ+ + YIHS + HRD+KP N+L T +K+CDFG A+ + G N
Sbjct: 654 MYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQL------LHGEPN-- 705
Query: 242 TNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKIL 301
+Y+ +R+YRAPELI Y+ +D+W+ GC+LAE +P+F G+ + Q++E+ K+L
Sbjct: 706 VSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVL 765
Query: 302 GTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYAS-SEAVDLMERLIDWNPEARL 360
GTP + IR + Y F PQ K PW ++F + +EA++L+ L+++ P AR+
Sbjct: 766 GTPTREQIREMNPN--YTEFKF--PQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARI 821
Query: 361 TVEEALDHPFLQQVRNPEAEPICPHG---PFDFTYEKHLYSME 400
T +A HPF ++R E P+G P F + +H S++
Sbjct: 822 TPLKACAHPFFDELR-MEGNHTLPNGRDMPPLFNFTEHELSIQ 863
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 82 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 137
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 138 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 195
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 196 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 248
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 249 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 308
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 309 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 363
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 364 HEYFRETPLPIDPSMFPTWP 383
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 414 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 469
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 470 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 527
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 528 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 580
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 581 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 640
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 641 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 695
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 696 HEYFRETPLPIDPSMFPTWP 715
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 423 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 478
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 479 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 589
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 649
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 650 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 704
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 705 HEYFRETPLPIDPSMFPTWP 724
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 104 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 159
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 160 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 217
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 218 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 270
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 271 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 330
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 331 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 385
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 386 HEYFRETPLPIDPSMFPTWP 405
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 208 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 263
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 264 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 321
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 322 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 374
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 375 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 434
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 435 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 489
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 490 HEYFRETPLPIDPSMFPTWP 509
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 391 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 446
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 447 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 504
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 505 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 557
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 558 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 617
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 618 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 672
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 673 HEYFRETPLPIDPSMFPTWP 692
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 380 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 435
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 436 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 493
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 494 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 546
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 547 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 606
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 607 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 661
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 662 HEYFRETPLPIDPSMFPTWP 681
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 169 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 224
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 225 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 282
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 283 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 335
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 336 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 395
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 396 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 450
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 451 HEYFRETPLPIDPSMFPTWP 470
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 425 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 480
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 481 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 538
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 539 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 591
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 592 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 651
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 652 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 706
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 707 HEYFRETPLPIDPSMFPTWP 726
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 142 bits (358), Expect = 1e-33
Identities = 98/320 (30%), Positives = 162/320 (50%), Gaps = 23/320 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T E+ +A+K++ +E ++RE+ + +
Sbjct: 438 FQCLNRIEEGTYGVVYRAKDK--KTDEI-VALKRLKMEKEKEGFPITSLREINTILKAQ- 493
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV++ EIV +Y V++DL ++ + F +K + Q+L G+K
Sbjct: 494 HPNIVTV--REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 551
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
++H ++HRDLK N+L S G +K+ DFGLAR G T V T WYR
Sbjct: 552 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY-------GSPLKAYTPVVVTLWYR 604
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L K YS +VDMW+VGCI E +KP+F G + Q+ ++ K LGTP + +
Sbjct: 605 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG 664
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEI----FPYASSEAVDLMERLIDWNPEARLTVEEALD 367
Y ++ + K + + P+ + S + DLM + + + P R++ E+ L
Sbjct: 665 YS-----ELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLK 719
Query: 368 HPFLQQVRNPEAEPICPHGP 387
H + ++ P + P P
Sbjct: 720 HEYFRETPLPIDPSMFPTWP 739
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 142 bits (358), Expect = 1e-33
Identities = 96/304 (31%), Positives = 150/304 (48%), Gaps = 23/304 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L+ +G+G+YG V A ++ T+ V +A+KK+ E + IRE+ + K
Sbjct: 5 FQKLEKIGEGTYGVVYKARERN--TNRV-VALKKIRLENENEGIPATTIREILLLKNLK- 60
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIH----SNVLFSEFHIKHFLYQILC 188
H IV L D+ N + +Y E V+ DL R + L E ++ Q+L
Sbjct: 61 HSTIVELSDVIYNNNK----MYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLT 116
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
M+Y HS ++ HRDLKP NIL IK+ DFGL R AG T V T
Sbjct: 117 AMEYCHSRNIFHRDLKPQNILVDPKENIKLADFGLGRA-------AGIPLRTYTTEVVTL 169
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYR PEL+L K Y SVD+W+ CI+AE +P F G+ + Q+ I K+LGTP
Sbjct: 170 WYRPPELLLGCKYYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNN-- 227
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
+ + + + P + IF + VDL+ ++++++P+ R+T + L H
Sbjct: 228 -SRWSNVENFPNYKVEFPVWDPVDLKTIF-RGDPDFVDLISKMLEYDPKMRMTAKNGLSH 285
Query: 369 PFLQ 372
+ +
Sbjct: 286 KYFE 289
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 142 bits (357), Expect = 1e-33
Identities = 102/319 (31%), Positives = 159/319 (48%), Gaps = 29/319 (9%)
Query: 75 ILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHR 134
I+QV G+G+YG V A N E +A+KK+ RE +IRE+K + F H
Sbjct: 186 IMQV-GEGTYGKVYKAK---NTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFD-HP 240
Query: 135 NIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI-HSNVLFSEFHIKHFLYQILCGMKYI 193
N+ ++ ++ + +++ +Y E D DL+ ++ + V S KH Q+L GM+Y+
Sbjct: 241 NVSTIKEIMVESQKT---VYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYL 297
Query: 194 HSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAP 253
H ++HRD+K NIL G +KI DFGLAR ++ TN V T WYR P
Sbjct: 298 HDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADY--------TNRVITLWYRPP 349
Query: 254 ELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYG 313
EL+L Y VDMW GC+L E + + +F G++ L Q+ I KI+GTP I ++
Sbjct: 350 ELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTP---TINSWP 406
Query: 314 SSRCYDIFSTSKPQYKKTPWCEIFP------YASSEAVDLMERLIDWNPEARLTVEEALD 367
+ F PQ + T + F SS+ + L L+ ++ R + EAL
Sbjct: 407 TLYDMPWFFMIMPQ-QTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQ 465
Query: 368 HPFLQQVRNPEAEPICPHG 386
+ ++ P+ EP+ G
Sbjct: 466 SDYFKE--EPKPEPLVLDG 482
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 141 bits (356), Expect = 2e-33
Identities = 91/323 (28%), Positives = 171/323 (52%), Gaps = 41/323 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y++++ LG+G Y V A++ N V +K V K+ RE+K + +G
Sbjct: 40 YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKK--------KKIKREVKILENLRG 91
Query: 133 HRNIVSLIDL--EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGM 190
NI+ LID + V++ P ++ + + D ++ + ++F I+ ++Y++L +
Sbjct: 92 GTNIIKLIDTVKDPVSKTP---ALVFEYINNTDFKQLYQ---ILTDFDIRFYMYELLKAL 145
Query: 191 KYIHSADVIHRDLKPGNILCSITGE-IKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
Y HS ++HRD+KP N++ + +++ D+GLA P+ VA+R+
Sbjct: 146 DYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPA--------QEYNVRVASRY 197
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAE-FYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
++ PEL++ ++ Y S+DMW++GC+LA + R+P F G D+ Q++ I K+LGT +
Sbjct: 198 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEE--- 254
Query: 309 IRTYGSSRCYDI-----FSTSKPQYKKTPW-----CEIFPYASSEAVDLMERLIDWNPEA 358
YG + Y I F+ Q+ + W E S EA+DL+++L+ ++ +
Sbjct: 255 --LYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQ 312
Query: 359 RLTVEEALDHPFLQQVRNPEAEP 381
RLT +EA++HP+ V +++P
Sbjct: 313 RLTAKEAMEHPYFYPVVKEQSQP 335
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 141 bits (356), Expect = 2e-33
Identities = 113/354 (31%), Positives = 170/354 (47%), Gaps = 62/354 (17%)
Query: 73 YEILQVLGKGSYGTVVSA--VDKGNPTHEVQLAIKKVTS---IFTREILLKRA-----IR 122
Y +V+G GS+G V A D G +AIKKV RE+ + R I
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGE-----LVAIKKVLQDKRFKNRELQIMRKLDHCNIV 110
Query: 123 ELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYC-YQELVDYDLAR-VIHSNVLFSEFHIK 180
L++ Y G + +E Y L Y Y +AR + ++K
Sbjct: 111 RLRYFFYSSGEKK-----------DEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVK 159
Query: 181 HFLYQILCGMKYIHSADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISN 239
++YQ+ + YIHS + HRD+KP N+L T +K+CDFG A+ + G N
Sbjct: 160 LYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL------VRGEPN 213
Query: 240 HITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQK 299
+Y+ +R+YRAPELI Y+ S+D+W+ GC+LAE +P+F G+ + Q++EI K
Sbjct: 214 --VSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
Query: 300 ILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCE-------------IF-PYASSEAV 345
+LGTP + IR + Y F PQ K PW + +F P EA+
Sbjct: 272 VLGTPTREQIREMNPN--YTEFKF--PQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAI 327
Query: 346 DLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGP-----FDFTYEK 394
L RL+++ P ARLT EA H F ++R+P + P+G F+FT ++
Sbjct: 328 ALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVK--LPNGRDTPALFNFTTQE 379
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 141 bits (355), Expect = 2e-33
Identities = 104/321 (32%), Positives = 159/321 (49%), Gaps = 30/321 (9%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+Y ++ +G+G+YG V A K P + AIKK + + AIRE+ +
Sbjct: 24 QYNLVGKIGEGTYGLVFLARTKTPPKRPI--AIKKFKQSKDGDGVSPTAIREIMLLREIS 81
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI--HSNVL---FSEFHIKHFLYQI 186
H N+V L+++ I + LY + +YDL +I H + + + + +K L+Q+
Sbjct: 82 -HENVVKLVNVHINFAD--MSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQL 138
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGE----IKICDFGLARGISPSFTVAGGISNHIT 242
L G+ Y+HS +IHRDLKP NIL E +KI DFGLAR
Sbjct: 139 LNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSD-----N 193
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDS--------LHQV 294
V T WYRAPEL+L K Y+ +VDMWAVGCI AE KP+F G ++ L Q+
Sbjct: 194 GVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQL 253
Query: 295 MEIQKILGTPKQIVIRTYGSSRCY--DIFSTSKPQYKKTPWCEIFPY-ASSEAVDLMERL 351
+I KILG P T + + D+ +Y + S A DL+ ++
Sbjct: 254 DKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKM 313
Query: 352 IDWNPEARLTVEEALDHPFLQ 372
++++P R+T +AL+H + +
Sbjct: 314 LEYDPLKRITASQALEHEYFR 334
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 140 bits (354), Expect = 3e-33
Identities = 101/320 (31%), Positives = 165/320 (51%), Gaps = 40/320 (12%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RYEIL+V+GKGS+G V+ A+D TH +AIK + + ++ L +A+ EL + +
Sbjct: 197 RYEILEVIGKGSFGQVIRALDHKTNTH---VAIKIIRN---KKRFLNQAVVELNILDELR 250
Query: 132 -----GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL--FSEFHIKHFLY 184
G N++ ++D + L EL+ +L +I N FS I+ F
Sbjct: 251 EKDADGSHNVIHMLDYTYFRKH----LCITFELMSLNLYELIKKNNYNGFSMSLIRRFCN 306
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGE--IKICDFGLARGISPSFTVAGGISNHIT 242
I+ ++ ++ ++IH DLKP NIL G IK+ DFG S + + I
Sbjct: 307 SIVKCLRLLYKENIIHCDLKPENILLKQRGSSSIKVIDFG-----SSCY-----VDRKIY 356
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
Y+ +R+YR+PE+IL +Y ++DMW++GCILAE Y P+F G + + Q+ I ++LG
Sbjct: 357 TYIQSRFYRSPEVILG-LQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLG 415
Query: 303 TPKQIVI------RTYGSSRCYDIFSTSKPQYKKTP----WCEIFPYASSEAVDLMERLI 352
P +++I R + SR T+ K++P I +D ++R +
Sbjct: 416 LPPKVLISVARRRRLFFDSRDAPRCITNTKGRKRSPGSKSLAHILHCQDRYFIDFLQRCL 475
Query: 353 DWNPEARLTVEEALDHPFLQ 372
+W+P R+T +EA H FLQ
Sbjct: 476 EWDPAERMTPDEAAHHEFLQ 495
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 139 bits (351), Expect = 6e-33
Identities = 104/317 (32%), Positives = 157/317 (48%), Gaps = 21/317 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L +G+GSYG V A D ++E+ +A+KKV ++ L +RE+ +
Sbjct: 53 FEKLNRVGEGSYGIVYRARD--TRSNEI-VALKKVRMDQEKDGLPISGLREIMILKQCH- 108
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H NIV L E+V + ++ + + DLA V+ + + F+E +K Q+L +K
Sbjct: 109 HENIVRL--REVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALK 166
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
Y+HS +IHRDLK N+L + G IK+ DFGLAR S +T + T WYR
Sbjct: 167 YLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNP-------PKPMTPQMVTLWYR 219
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L + ++ +VDMWA GCIL E KP+ GN + Q+ I +LG P + +
Sbjct: 220 APELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPG 279
Query: 312 YGSSRCYDIFSTSKPQYKK-TPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
+ F+ S+ Y TP F +L+ L +NP+ R T EE L +
Sbjct: 280 FADLPAVQNFTLSQQPYNNLTP---KFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKY 336
Query: 371 L---QQVRNPEAEPICP 384
Q +P P P
Sbjct: 337 FVDPPQACDPGMMPTFP 353
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 139 bits (350), Expect = 8e-33
Identities = 97/308 (31%), Positives = 161/308 (51%), Gaps = 22/308 (7%)
Query: 73 YEILQVLGKGSYGTVVSA--VDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYF 130
++ L+ +G+G+Y +V A V+ G +A+KKV + ++ RE+ +
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVETGK-----MVALKKVKFDNLQPESIRFMAREILILRKL 159
Query: 131 KGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCG 189
H NI+ L IV S +Y E +++DLA + + ++ F+E IK ++ Q+L G
Sbjct: 160 N-HPNIMKLEG--IVTSRASSSIYLVFEYMEHDLAGLSSNPDIRFTEPQIKCYMKQLLWG 216
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+++ H VIHRD+K NIL + G +K+ DFGLA ++PS N +T+ V T W
Sbjct: 217 LEHCHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSN------KNQLTSRVVTLW 270
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YRAPEL++ Y SVD+W+VGC+ AE KP+ G + Q+ +I K+ G+P+
Sbjct: 271 YRAPELLMGSTSYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSPQD--- 327
Query: 310 RTYGSSRCYDIFSTSKPQYK-KTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
++ ++ KPQ+ + E S+ V L+E L+ P+ R T AL+
Sbjct: 328 -SFWKRTKLPHATSFKPQHTYEATLRERCKDLSATGVYLLETLLSMEPDKRGTASSALNS 386
Query: 369 PFLQQVRN 376
+V+N
Sbjct: 387 EDTLEVKN 394
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 139 bits (349), Expect = 1e-32
Identities = 94/300 (31%), Positives = 151/300 (50%), Gaps = 17/300 (5%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G+G+Y V ++AIK++ + ++ L AIRE+K++ + H N++
Sbjct: 13 VGEGTYAVVYLGCQHSTGR---KIAIKEIKTSEFKDGLDMSAIREVKYLQEMQ-HPNVIE 68
Query: 139 LIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMKYIHSAD 197
LID+ + Y L E + DL VI ++LF+ IK ++ L G+ + H
Sbjct: 69 LIDIFMA----YDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNF 124
Query: 198 VIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELIL 257
++HRDLKP N+L S G+IK+ DFGLAR I + +T+ V TRWYRAPEL+
Sbjct: 125 ILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEI-------LTSNVVTRWYRAPELLF 177
Query: 258 SHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRC 317
K Y+ ++D+W+VG I AE R P G + + Q+ + LGTP S
Sbjct: 178 GAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMT 237
Query: 318 YDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNP 377
Y+ P + + F AS A+D M ++ NP+ R T + L+ + +++ P
Sbjct: 238 YNKLQIYPPP-SRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPP 296
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 139 bits (349), Expect = 1e-32
Identities = 101/310 (32%), Positives = 160/310 (51%), Gaps = 25/310 (8%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE + +G+G+YG V A D N V A+K+V E + IRE+ + + +
Sbjct: 12 QYECVAEIGEGAYGKVFKARDLKNGGRFV--ALKRVRVQTGEEGMPLSTIREVAVLRHLE 69
Query: 132 G--HRNIVSLIDLEIVNE-EPYSGLYCYQELVDYDLARVIHS--NVLFSEFHIKHFLYQI 186
H N+V L D+ V+ + + L E VD DL + IK ++Q+
Sbjct: 70 TFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQL 129
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVA 246
L G+ ++HS V+HRDLKP NIL + +G+IK+ DFGLAR S F +A +T+ V
Sbjct: 130 LRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYS--FQMA------LTSVVV 181
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
T WYRAPE++L Y+ VD+W+VGCI AE + RKP+F G+ + Q+ +I ++G P +
Sbjct: 182 TLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE 240
Query: 307 IVIRTYGSSRCYDIFSTSKPQYKKT--PWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
D+ + + K+ P + DL+ + + +NP R++
Sbjct: 241 -------EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYS 293
Query: 365 ALDHPFLQQV 374
AL HP+ Q +
Sbjct: 294 ALSHPYFQDL 303
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 138 bits (348), Expect = 1e-32
Identities = 112/364 (30%), Positives = 174/364 (47%), Gaps = 37/364 (10%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F Y L+ LG+GSY TV + + N QL KV S+ E + AIRE
Sbjct: 46 FGAASSYLNLEKLGEGSYATVYKGISRING----QLVALKVISMNAEEGVPFTAIREASL 101
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI--HSNVLFSEFHIKHFLY 184
+ K H NIV L D+ I +E + ++ Y DLA+ + H L +++ F++
Sbjct: 102 LKGLK-HANIVLLHDI-IHTKETLTFVFEYMHT---DLAQYMSQHPGGLHPH-NVRLFMF 155
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS-PSFTVAGGISNHITN 243
Q+L G+ YIH V+HRDLKP N+L S GE+K+ DFGLAR S PS T ++
Sbjct: 156 QLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQT--------YSS 207
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMG-NDSLHQVMEIQKILG 302
V T WYR P+ +L YS +D+W GCI E + +P+F G ++ L Q+ +I ++LG
Sbjct: 208 EVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLG 267
Query: 303 TPKQIVIRTYGSSRCY--DIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARL 360
P + Y + F P+ W + EA DL +++ P R+
Sbjct: 268 VPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRL--GRVPEAEDLASQMLKGFPRDRV 325
Query: 361 TVEEALDHPFLQQVRNPEAEPICPHGPFDFTYEKHLYSME--RLRECLCDEVSKFHNDRQ 418
+ +EAL H + + P + E+ L+++ RL+ +CD ++ +
Sbjct: 326 SAQEALVHDYFSAL---------PSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHH 376
Query: 419 TKDF 422
F
Sbjct: 377 PAQF 380
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 138 bits (347), Expect = 2e-32
Identities = 101/307 (32%), Positives = 155/307 (49%), Gaps = 34/307 (11%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y+ ++ +G+G+YGTV A +K + E+ +A+K+V E + A+RE+ + K
Sbjct: 4 YDKMEKIGEGTYGTVFKARNKNSG--EI-VALKRVRLDDDDEGVPSSALREICILRELK- 59
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
HRN+V L D +V+ E + L E D DL + S N + + Q+L G+
Sbjct: 60 HRNVVRLYD--VVHSE--NKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLS 115
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ H+ V+HRDLKP N+L + G +K+ DFGLAR G + V T WYR
Sbjct: 116 FCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAF-------GVPVRCFSAEVVTLWYR 168
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGR-KPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
P+++ K Y+ S+DMW+ GCI AE +P+F G D Q+ I K LG+P +
Sbjct: 169 PPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSE---D 225
Query: 311 TYGSSRCYDIFSTSKPQYKKTP-------WCEIFPYASSEAVDLMERLIDWNPEARLTVE 363
+ S T P YK P W +I P +S DL+++L+ NP R+ +
Sbjct: 226 NWPS-------ITQLPDYKPYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAGRIDAD 278
Query: 364 EALDHPF 370
AL H +
Sbjct: 279 AALRHAY 285
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 137 bits (346), Expect = 2e-32
Identities = 102/317 (32%), Positives = 152/317 (47%), Gaps = 35/317 (11%)
Query: 70 PGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSY 129
P RY++L+ +G+G +G V A+D ++AIKKV + +RE+K +
Sbjct: 6 PSRYKMLEKIGEGVHGCVFKAIDL---QRNKEVAIKKVALKNKFGNIALNTLREIKTLQL 62
Query: 130 FKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILC 188
K I+ +ID+ +GL E L + S V S ++ F +Q+
Sbjct: 63 CKSEY-ILDIIDIY----PDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFK 117
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
G+ Y+H A ++HRD+KP N+L S T +KI DFGLAR P S + V+TR
Sbjct: 118 GIAYLHEAGLMHRDIKPANLLISDTDMLKIADFGLARLYFPEDE-----SRLYSPQVSTR 172
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYRAPE++ ++Y VDMWA GC++AE P+F G + Q+ I+
Sbjct: 173 WYRAPEILFGSQKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQL-----------AII 221
Query: 309 IRTYGSSRCYDIFS-TSKPQYKK--------TPWCEIFPYAS-SEAVDLMERLIDWNPEA 358
IRT GS R TS P Y K W +FP + + ++L+ L+ +NP+
Sbjct: 222 IRTLGSPRLNQWPELTSLPDYSKIRFPNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKN 281
Query: 359 RLTVEEALDHPFLQQVR 375
RL E L VR
Sbjct: 282 RLKASEVGSASSLTPVR 298
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 137 bits (345), Expect = 3e-32
Identities = 109/314 (34%), Positives = 152/314 (47%), Gaps = 26/314 (8%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F YE L+ LG+GSY TV K N +L KV + E AIRE
Sbjct: 111 FGKADSYEKLEKLGEGSYATVYKGKSKVNG----KLVALKVIRLQEEEGTPFTAIREASL 166
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI--HSNVLFSEFHIKHFLY 184
+ K H NIV L D+ E L E V DL + + H L + ++K FL+
Sbjct: 167 LKGLK-HANIVLLHDIIHTKET----LTLVFEYVHTDLCQYMDKHPGGLHPD-NVKLFLF 220
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS-PSFTVAGGISNHITN 243
Q+L G+ YIH ++HRDLKP N+L S TGE+K+ DFGLAR S PS T +N
Sbjct: 221 QLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHT--------YSN 272
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMG-NDSLHQVMEIQKILG 302
V T WYR P+++L YS +DMW VGCI E F G D Q+ I +LG
Sbjct: 273 EVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLG 332
Query: 303 TPKQIVIRTYGSSRCY--DIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARL 360
TP + S + + F+ + + W ++ Y + A DL +L+ +P+ RL
Sbjct: 333 TPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKL-SYV-NHAEDLASKLLQCSPKNRL 390
Query: 361 TVEEALDHPFLQQV 374
+ + AL H + +
Sbjct: 391 SAQAALSHEYFSDL 404
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 137 bits (345), Expect = 3e-32
Identities = 109/313 (34%), Positives = 161/313 (50%), Gaps = 32/313 (10%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y +++G+GS+G V A K T E +AIKKV + REL+ M
Sbjct: 74 YMAERIVGQGSFGIVFQA--KCLETGET-VAIKKVLQD------KRYKNRELQTMRLLD- 123
Query: 133 HRNIVSLIDLEI-VNEEPYSGLYCYQELVDYDLARVI----HSNVLFSEFHIKHFLYQIL 187
H N+VSL E+ L E V + RV +N ++K + YQI
Sbjct: 124 HPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQIC 183
Query: 188 CGMKYIHSA-DVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+ YIH V HRD+KP N+L + T ++K+CDFG A+ + G N +Y+
Sbjct: 184 RALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK------VLVKGEPN--ISYI 235
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
+R+YRAPELI Y+ ++D+W+ GC+LAE +P+F G + Q++EI K+LGTP
Sbjct: 236 CSRYYRAPELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPT 295
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEE 364
+ I+ + Y F PQ K PW +IF EAVDL+ RL+ ++P R T
Sbjct: 296 REEIKCMNPN--YTEFKF--PQIKAHPWHKIFHKRTPPEAVDLVSRLLQYSPNLRSTA-- 349
Query: 365 ALDHPFLQQVRNP 377
A+ HPF ++R+P
Sbjct: 350 AIVHPFFDELRDP 362
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 136 bits (343), Expect = 5e-32
Identities = 106/308 (34%), Positives = 156/308 (50%), Gaps = 26/308 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y L+ LG+GSY TV K T++ ++A+K++ + E AIRE + K
Sbjct: 192 YVKLEPLGEGSYATVYKGFSK--LTYQ-RVALKEIR-LQEEEGAPFTAIREASLLKELK- 246
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILCGMK 191
H NIV+L D+ E L E V+ DL++ + + +++ FL+Q+L G+
Sbjct: 247 HSNIVTLHDIVHTRET----LTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLS 302
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS-PSFTVAGGISNHITNYVATRWY 250
Y H V+HRD+KP N+L S GE+K+ DFGLAR S PS T ++ V T WY
Sbjct: 303 YCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHT--------YSHEVVTLWY 354
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMG-NDSLHQVMEIQKILGTPKQIVI 309
R P+++L YS S+DMW VGCI E P F G D+ Q+ +I K+LGTP +
Sbjct: 355 RPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTE--- 411
Query: 310 RTYGSSRCYDIFSTSK-PQYKKTPWCEIFP--YASSEAVDLMERLIDWNPEARLTVEEAL 366
T+ + + K Y+ FP Y E + + NPE RL ++AL
Sbjct: 412 DTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDAL 471
Query: 367 DHPFLQQV 374
HP+ Q+
Sbjct: 472 QHPYFAQL 479
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 135 bits (341), Expect = 9e-32
Identities = 95/327 (29%), Positives = 165/327 (50%), Gaps = 53/327 (16%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y++++ LG+G Y V A+ N T+ ++ +K + + K+ RE+K + +G
Sbjct: 39 YQLVRKLGRGKYSEVFEAI---NITNNEKVVVK-----ILKPVKKKKIKREIKILENLRG 90
Query: 133 HRNIVSLIDL-------------EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHI 179
NI++L D+ E VN + LY Q L DYD I
Sbjct: 91 GPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLY--QTLTDYD---------------I 133
Query: 180 KHFLYQILCGMKYIHSADVIHRDLKPGNILCSITG-EIKICDFGLARGISPSFTVAGGIS 238
+ ++Y+IL + Y HS ++HRD+KP N++ ++++ D+GLA P
Sbjct: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG-------- 185
Query: 239 NHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRK-PVFMGNDSLHQVMEI 297
VA+R+++ PEL++ ++ Y S+DMW++GC+LA RK P F G+D+ Q++ I
Sbjct: 186 QEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRI 245
Query: 298 QKILGTPKQI-VIRTYG---SSRCYDIFST-SKPQYKKTPWCEIFPYASSEAVDLMERLI 352
K+LGT I Y R DI S+ ++++ E S EA+D +++L+
Sbjct: 246 AKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLL 305
Query: 353 DWNPEARLTVEEALDHPFLQQVRNPEA 379
++ ++RLT EA++HP+ V +A
Sbjct: 306 RYDHQSRLTAREAMEHPYFYTVVKDQA 332
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 135 bits (340), Expect = 1e-31
Identities = 90/299 (30%), Positives = 151/299 (50%), Gaps = 18/299 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE L +G+GSYGTV+ K Q+ K+ + + K A+RE+KF+ F
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTG----QIVAIKIFYERPEQSVNKIAMREIKFLKQFH- 58
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYD-LARVIHSNVLFSEFHIKHFLYQILCGMK 191
H N+V+LI++ ++ ++ E +D+ L + H ++ +L+QIL +
Sbjct: 59 HENLVNLIEVFRQKKK----IHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAID 114
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
Y+HS ++IHRD+KP NIL S +G K+CDFG AR ++ + T+YVATRWYR
Sbjct: 115 YLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDI-------YTDYVATRWYR 167
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L Y K VD+WA+GC++ E P + L + +I +G +
Sbjct: 168 APELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNI 227
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
+ S + + Q+ K + +P + D++ + +P R++ + L H +
Sbjct: 228 FSKSPIFAGVVLPQVQHPKNA-RKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEY 285
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 135 bits (340), Expect = 1e-31
Identities = 85/235 (36%), Positives = 124/235 (52%), Gaps = 33/235 (14%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RYE +QV G+G++G VV A D ++AIK++ ++ L R I L+ +
Sbjct: 7 RYETIQVAGRGAFGLVVIARDT---LTSKRVAIKRIMVPNVSKVSLAREISCLRNLH--- 60
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMK 191
HRNI+ L+D C+ DL ++ V ++ ++ QIL G+
Sbjct: 61 -HRNILKLLD-------------CFPSA---DLMSIVTEEVPYTWYYT-----QILSGIA 98
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
Y+HS +++HRD+KP NIL + +KI DFG A F + + VATRWYR
Sbjct: 99 YLHSKEIMHRDIKPENILVTSRNVVKIADFGQA-----CFYMPKDPNQEYDVNVATRWYR 153
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
APEL+ K+Y VD+WA+GCILAE KP+F G L Q+ I +LGTP +
Sbjct: 154 APELLFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNE 208
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 135 bits (339), Expect = 2e-31
Identities = 89/306 (29%), Positives = 153/306 (49%), Gaps = 29/306 (9%)
Query: 77 QVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS---IFTREILLKRAIRELKF--MSYFK 131
+V+G GS+G V + V + T+E ++AIKKV RE+ + + + + + YF
Sbjct: 43 EVVGHGSFGVVFATVIQ--ETNE-KVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFF 99
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMK 191
R+ I L ++ E LY L +H S IK++++Q+ +
Sbjct: 100 YERDSQDEIYLNLILEYMPQSLY-------QRLRHFVHQRTPMSRLEIKYYMFQLFKSLN 152
Query: 192 YIHS-ADVIHRDLKPGNILCSI-TGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
Y+H A+V HRD+KP N+L T +K+CDFG A+ + P+ +Y+ +R+
Sbjct: 153 YLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPT--------EPNVSYICSRY 204
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YRAPELI Y+ +D+W+ GC++AE +P+F G + Q++EI KILGTP + I
Sbjct: 205 YRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEI 264
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ + F PQ K P +F + V+ + ++ ++P R + L P
Sbjct: 265 CSMNPNYMEHKF----PQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSP 320
Query: 370 FLQQVR 375
+ +++
Sbjct: 321 YFDELK 326
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 135 bits (339), Expect = 2e-31
Identities = 96/310 (30%), Positives = 154/310 (48%), Gaps = 17/310 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE + + +G++G V DK T E+ +A+K++ +E A+RE+ +
Sbjct: 356 YECVNRVDEGTFGVVYRGKDKR--TDEI-VALKRLKMEKEKEGFPITALREINMLLKAGN 412
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS----NVLFSEFHIKHFLYQILC 188
H NIV++ EI+ +Y E V++D+ ++ + N FS K L Q+L
Sbjct: 413 HPNIVNV--KEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLS 470
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATR 248
G++++H ++HRDLK N+L S G +KI DFGLAR G T+ V T
Sbjct: 471 GIEHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREY-------GDPLKKFTSIVVTL 523
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIV 308
WYR+PEL+L + YS VDMW+VGCI+AEF KP+F G L Q+ +I +GTP + +
Sbjct: 524 WYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESI 583
Query: 309 IRTYGSSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLMERLIDWNPEARLTVEEALD 367
+ + K Y + + + L+ L+ +P+ R + +ALD
Sbjct: 584 WPGVTELDGWKALTFEKYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALD 643
Query: 368 HPFLQQVRNP 377
H + + P
Sbjct: 644 HEWFTEEPYP 653
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 135 bits (339), Expect = 2e-31
Identities = 93/301 (30%), Positives = 149/301 (48%), Gaps = 16/301 (5%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L+ +G+G+Y +V A D T+ +A+K+V + +K RE+ M
Sbjct: 137 FEKLEKIGQGTYSSVYKARDL---TNNKIVALKRVRFDLSDLESVKFMAREIIVMRRLD- 192
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIH-SNVLFSEFHIKHFLYQILCGMK 191
H N++ L L + S LY E +D+DL + + FSE +K ++ Q+L G+
Sbjct: 193 HPNVLKLEGL--ITASVSSSLYLVFEYMDHDLVGLASIPGIKFSEPQVKCYMQQLLSGLH 250
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ HS V+HRD+K N+L G +KI DFGLA P V +T+ V T WYR
Sbjct: 251 HCHSRGVLHRDIKGSNLLIDSNGVLKIADFGLATFFDPQNCVP------LTSRVVTLWYR 304
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
PEL+L Y VD+W+ GCIL E Y KP+ G + Q+ +I K+ G+P + R
Sbjct: 305 PPELLLGACHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPTEDYWRK 364
Query: 312 YGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFL 371
F + P ++ E+F + + L+E L+ +P+ R + AL+ +
Sbjct: 365 LKLPPS-AAFRPALPYGRRV--AEMFKDLPTNVLSLLEALLSIDPDRRGSAARALESEYF 421
Query: 372 Q 372
+
Sbjct: 422 R 422
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 134 bits (338), Expect = 2e-31
Identities = 98/328 (29%), Positives = 165/328 (49%), Gaps = 44/328 (13%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKK-------VTSIFTREILLKRAIRELK 125
Y+I+ + G+YG V AV N + AIKK V+S + + + AIRE+
Sbjct: 5 YKIIGFISSGTYGKVYKAVSS-NSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMM 63
Query: 126 FMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHI-----K 180
+ H NIVSL+ + ++ + S ++ Y E +DL ++IH + I K
Sbjct: 64 LCREIQ-HENIVSLVQV-LLKDGTISMVFEYAE---HDLLQIIHFHSRSRTRQIPPSILK 118
Query: 181 HFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLAR----GISPSFTVAGG 236
L+QI+ G+ Y+H ++HRDLKP NI+ + TG++KI D GL R I P ++
Sbjct: 119 SILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYS---- 174
Query: 237 ISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGND------- 289
S+ + V T WYRAPEL+L Y+ ++D+WA+GCI E P+F G++
Sbjct: 175 -SDRV---VVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKK 230
Query: 290 ----SLHQVMEIQKILGTPKQ---IVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASS 342
Q++ I ++LGTP + ++ Y F W +
Sbjct: 231 VVPFQSTQMLRIMELLGTPTEERWPGLKNYPEYYQLSSFEVRYWNNLLPQWYQTVKNRDP 290
Query: 343 EAVDLMERLIDWNPEARLTVEEALDHPF 370
+ +DL+ +++ ++P++R+T ++AL+H F
Sbjct: 291 QGLDLLMKMLQYDPKSRITAKQALEHVF 318
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 134 bits (336), Expect = 4e-31
Identities = 88/307 (28%), Positives = 147/307 (47%), Gaps = 27/307 (8%)
Query: 102 LAIKKVTSIFTRE----ILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYC-- 155
L I + ++T+E L R REL+ M H NI+ LI + +
Sbjct: 10 LLILALVFLYTKENSIYFTLHRVNRELQIMRAIS-HPNIIKLIAFFHTHNPSKDETHLCL 68
Query: 156 ----YQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCS 211
E V D+ IK + +Q+ + Y+HS V HRD+KP N+L
Sbjct: 69 LLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVD 128
Query: 212 I-TGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWA 270
TG +K+CDFG A+ + PS +Y+ +R+YRAPEL+ Y+ +D+W+
Sbjct: 129 YKTGILKLCDFGSAKVLVPS--------EPNVSYICSRYYRAPELVFGATHYTTKIDVWS 180
Query: 271 VGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKK 330
C++AE + +P+F G+ S+ Q++EI ++LGTP I + + S P +
Sbjct: 181 AACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMNP----NYVNHSLPNVRP 236
Query: 331 TPWCEIFPY-ASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPICPHGPFD 389
+ P+ + A+DL+ +++ + P R++ E L HPF ++R+P C +
Sbjct: 237 HTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDELRDPNCMYHCSRD--E 294
Query: 390 FTYEKHL 396
T E+HL
Sbjct: 295 GTIERHL 301
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 133 bits (335), Expect = 5e-31
Identities = 94/317 (29%), Positives = 151/317 (46%), Gaps = 38/317 (11%)
Query: 70 PGR---YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
PGR +E + +G G++ V A D +A+K++ +K RE+
Sbjct: 97 PGRESHFEKQEQIGGGTFSKVFKARDL---LRNKTVALKRIRFDINNSESIKCIAREIII 153
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQ 185
+ H N++ L L +V+ + S LY E +++DL + V FSE +K ++ Q
Sbjct: 154 LRKLD-HPNVIKLEGLMLVDHDS-STLYLIFEYMEHDLLGLSSLLGVHFSEPQVKCYMRQ 211
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+L G+ + H+ V+HRD+K N+L + G +KI DFGLA P +V +T +V
Sbjct: 212 LLRGLDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLATFFDPHNSVP------LTTHV 265
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPK 305
AT WYR PEL+L Y VD+W+ GC++ E Y KP+ G + Q+ +I K+ G+P
Sbjct: 266 ATLWYRPPELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPS 325
Query: 306 QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYAS----------SEAVDLMERLIDWN 355
D + T TP I+PY S + + L+E L+ +
Sbjct: 326 -------------DDYWTKLKLQLSTPLRPIYPYGSHIAETFKQFPASVISLLETLLSID 372
Query: 356 PEARLTVEEALDHPFLQ 372
P+ R T AL + +
Sbjct: 373 PDFRGTAASALKSKYFK 389
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 133 bits (335), Expect = 5e-31
Identities = 98/324 (30%), Positives = 164/324 (50%), Gaps = 23/324 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
++ L + +G+YG V A DK T+E+ +A+K++ +E ++RE+ + KG
Sbjct: 558 FQCLNRIEEGTYGVVYRAKDKR--TNEI-VALKRLKMEKEKEGFPITSLREINTL--LKG 612
Query: 133 -HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS----NVLFSEFHIKHFLYQIL 187
H NIV++ EIV ++ + V++DL ++ + F +K Q+L
Sbjct: 613 QHPNIVTV--REIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLL 670
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVAT 247
+ ++H ++HRDLK N+L S G +K+ DFGLAR G T+ V T
Sbjct: 671 RAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREY-------GSPIKKYTSLVVT 723
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
WYRAPEL+L YS +D+W+VGCI AEF P+F G + ++ I K LGTP +
Sbjct: 724 LWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEK 783
Query: 308 VIRTYGSSRCYDIFSTSKPQYKKTPWCEI---FPYASSE-AVDLMERLIDWNPEARLTVE 363
+ Y + Q+ + P ++ F +SE + L++ L+ ++P+ RL+ +
Sbjct: 784 IWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSAD 843
Query: 364 EALDHPFLQQVRNPEAEPICPHGP 387
AL H F +++ P + P P
Sbjct: 844 AALKHGFFKELPLPIDPSMFPTWP 867
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 133 bits (334), Expect = 6e-31
Identities = 98/308 (31%), Positives = 154/308 (49%), Gaps = 34/308 (11%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKV---------TSIFTREILLKRAIRE 123
+E L+ +G+G+Y +V A D T+++ +A+KKV REI++ R +
Sbjct: 163 FEKLEKIGQGTYSSVYKARDL--ETNQL-VALKKVRFANMDPDSVRFMAREIIILRRL-- 217
Query: 124 LKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHF 182
H N++ L L + +Y E +++DLA + + + FSE IK +
Sbjct: 218 --------DHPNVMKLEGL--ITSRVSGSMYLIFEYMEHDLAGLASTPGINFSEAQIKCY 267
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
+ Q+L G+++ HS V+HRD+K N+L +KI DFGLA G +T
Sbjct: 268 MKQLLHGLEHCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQ------GHQKQPLT 321
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+ V T WYR PEL+L Y +VD+W+ GCILAE + KP+ G + Q+ +I K+ G
Sbjct: 322 SRVVTLWYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCG 381
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
+P + + IF +P YK+ E F S A+ L+E L+ P+AR T
Sbjct: 382 SPSEEYWKISKLPHA-TIFKPQQP-YKRCV-AETFKSLPSSALALVEVLLAVEPDARGTT 438
Query: 363 EEALDHPF 370
AL+ F
Sbjct: 439 ASALESEF 446
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 132 bits (333), Expect = 8e-31
Identities = 86/316 (27%), Positives = 154/316 (48%), Gaps = 23/316 (7%)
Query: 73 YEILQVLGKGSYGTVVS--AVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYF 130
Y+ + +G+G++ V+ ++ GN A K++ F I +RE++ +
Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGN-----YYACKQMKQRF-ESIEQVNNLREIQALRRL 57
Query: 131 KGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHFLYQILCG 189
H NI+ L ++ + L C EL+D ++ +I SE I H++YQ+
Sbjct: 58 NPHPNILMLHEVVFDRKSGSLALIC--ELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKS 115
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+ +IH + HRD+KP NIL +K+ DFG R + T Y++TRW
Sbjct: 116 LDHIHRNGIFHRDVKPENILIK-QDVLKLGDFGSCRSVYSK--------QPYTEYISTRW 166
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YRAPE +L+ Y+ +D+W+ GC+ E +P+F G + L Q+ +I ++GTP Q ++
Sbjct: 167 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKIL 226
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ SR + P K + + S + + L+ ++ ++P+ R+ +AL HP
Sbjct: 227 TKFKQSRAMNF---DFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHP 283
Query: 370 FLQQVRNPEAEPICPH 385
+ Q+ R E + H
Sbjct: 284 YFQEQRKTEKRALGSH 299
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 132 bits (331), Expect = 1e-30
Identities = 95/307 (30%), Positives = 155/307 (49%), Gaps = 23/307 (7%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE ++++G+G++G V+ A KG + A+KKV+ +E L IRE++ + G
Sbjct: 22 YEKIRIIGEGTFGQVILA-RKGRARY----ALKKVSK--EKEGLSVTTIREVQVLRAM-G 73
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKY 192
H +IV LI++ + EP +Y YDL R I SN + IKH YQI G+ Y
Sbjct: 74 HPSIVRLIEVVV---EPGGDIYMVFPYFPYDLNRFIRSNKMTCS-EIKHIFYQIAQGVCY 129
Query: 193 IHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRA 252
IHS ++HRDLK NIL I DFG+AR +T G T + T WYRA
Sbjct: 130 IHSKGIMHRDLKSANILLDQKLNASIADFGMAR-----YTTKTGA---YTPGMVTLWYRA 181
Query: 253 PELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRTY 312
PE++L Y+ +VD+W++GCIL E Y +F G+ ++++++ ++ I +Y
Sbjct: 182 PEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGST---EMLQLEMVIHACGSINENSY 238
Query: 313 GSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQ 372
+ F + I + AV+L+ +++ +P R+TVE+ + + +
Sbjct: 239 PGVQDLPGFRNFRLPQSPRRIEGIIRKHDASAVELVSKMLCLDPSKRITVEQVVGSKYFE 298
Query: 373 QVRNPEA 379
+A
Sbjct: 299 HEARRDA 305
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 132 bits (331), Expect = 1e-30
Identities = 99/312 (31%), Positives = 154/312 (48%), Gaps = 42/312 (13%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKV---------TSIFTREILLKRAIRE 123
+E + +G+G+Y V A D T ++ +A+KKV REIL+ R +
Sbjct: 118 FEKIDKIGQGTYSNVYKAKDM--LTGKI-VALKKVRFDNLEPESVKFMAREILVLRRL-- 172
Query: 124 LKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHF 182
H N+V L L V LY + +D+DLA + S V+ FSE +K
Sbjct: 173 --------DHPNVVKLEGL--VTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCL 222
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
+ Q++ G+++ HS V+HRD+K N+L G +KI DFGLA P+ +T
Sbjct: 223 MRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNH------KRPMT 276
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+ V T WYRAPEL+L Y +D+W+ GCILAE +P+ G + Q+ +I K+ G
Sbjct: 277 SRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCG 336
Query: 303 TPKQIVIR----TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEA 358
+P + + T+G+ I+ +P YK++ E F ++ L++ L+ PE
Sbjct: 337 SPSEDYWKKGKFTHGA-----IYKPREP-YKRS-IRETFKDFPPSSLPLIDALLSIEPED 389
Query: 359 RLTVEEALDHPF 370
R T AL F
Sbjct: 390 RQTASAALKSEF 401
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 131 bits (330), Expect = 2e-30
Identities = 93/301 (30%), Positives = 148/301 (48%), Gaps = 20/301 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L +G+G+Y +V A D +A+KKV + ++ RE+ +
Sbjct: 156 FEKLDKIGQGTYSSVYRARDLETGK---MVAMKKVRFVNMDPESVRFMAREINILRKLD- 211
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARV-IHSNVLFSEFHIKHFLYQILCGMK 191
H N++ L L V + LY E +++DL+ + + V F+E IK ++ Q+L G++
Sbjct: 212 HPNVMKLECL--VTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQIKCYMKQLLSGLE 269
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ HS ++HRD+K N+L + G +KI DFGLA P +T+ V T WYR
Sbjct: 270 HCHSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQ------DQPLTSRVVTLWYR 323
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L Y +D+W+VGCIL E + KP+ G + Q+ +I K G+P
Sbjct: 324 APELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSD----D 379
Query: 312 YGSSRCYDIFSTSKPQ--YKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
Y + ++ KPQ YK+ E F A+ L+++L+ P R T L
Sbjct: 380 YWQKTKLPLATSFKPQQPYKRV-LLETFKNLPPSALALVDKLLSLEPAKRGTASSTLSSK 438
Query: 370 F 370
F
Sbjct: 439 F 439
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 130 bits (327), Expect = 4e-30
Identities = 104/329 (31%), Positives = 165/329 (49%), Gaps = 34/329 (10%)
Query: 56 LTKRSIYSPANFS---VPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFT 112
++ SIYS + + RY + Q LG GS+GTV A K +A+KK+ +
Sbjct: 1 MSNESIYSVLDLTQVIFEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSK 60
Query: 113 ---REILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVI- 168
+ LLK +RE + H ++ L++ + +PY ++ E +D +L ++
Sbjct: 61 PKPKHELLK--LRESLALRKISKHPCLIDLLETFM---DPYRNIFLVMEFMDCNLFQLFK 115
Query: 169 -HSNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILC--------SITGEIKIC 219
LF++ + L QI+ G+++IH +HRD+KP NIL S IK+
Sbjct: 116 RRQGRLFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLG 175
Query: 220 DFGLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFY 279
DFGLAR PS + S+ +T YV+TRWYRAPEL+L Y+ SVD++A GCI+ E Y
Sbjct: 176 DFGLAR---PSVS-----SDPLTEYVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEIY 227
Query: 280 GRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT-YGSSRCYDI---FSTSKPQYKKTPWCE 335
KP+F G + Q+ + +ILG P + T + S+ ++ P K P +
Sbjct: 228 SLKPLFPGRNETDQLNRVCEILGNPGIDELDTLHYWSQAKELAKRLGFMLPPTKPYPIQK 287
Query: 336 IFPYASSEA-VDLMERLIDWNPEARLTVE 363
+ P E ++ L+ WNP+ R T +
Sbjct: 288 LLPQNCPEGHAKMIPCLLAWNPDVRPTAK 316
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 129 bits (325), Expect = 7e-30
Identities = 83/314 (26%), Positives = 159/314 (50%), Gaps = 27/314 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE+++ +G+G Y V ++ N + +K V K+ RE+K + G
Sbjct: 34 YEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKK--------KKIRREIKILQNLCG 85
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKY 192
NIV L+D +V ++ E V+ +V++ + +++ I++++Y++L + +
Sbjct: 86 GPNIVKLLD--VVRDQHSKTPSLIFEYVNSTDFKVLYPTL--TDYDIRYYIYELLKALDF 141
Query: 193 IHSADVIHRDLKPGNILCSIT-GEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
HS ++HRD+KP N++ ++++ D+GLA P VA+R+++
Sbjct: 142 CHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPG--------KEYNVRVASRYFK 193
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRK-PVFMGNDSLHQVMEIQKILGTPKQIVIR 310
PEL++ + Y S+DMW++GC+ A RK P F G+D+ Q+++I K+LGT +
Sbjct: 194 GPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYL 253
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIF-----PYASSEAVDLMERLIDWNPEARLTVEEA 365
++ + PW + S EA+D +++L+ ++ + RLT +EA
Sbjct: 254 NKYQLELDTQLEALVGRHSRKPWSKFINADNRHLVSPEAIDYLDKLLRYDHQDRLTAKEA 313
Query: 366 LDHPFLQQVRNPEA 379
+ HP+ QVR E+
Sbjct: 314 MAHPYFAQVRAAES 327
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 129 bits (325), Expect = 7e-30
Identities = 95/302 (31%), Positives = 146/302 (47%), Gaps = 19/302 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDK--GNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYF 130
+E + +G G+Y V A D GN +A+KKV LK RE+ +
Sbjct: 138 FEKIDKIGSGTYSNVYKAKDSLTGNI-----VALKKVRCDVNERESLKFMAREILILRRL 192
Query: 131 KGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCG 189
H N++ L L V S LY +D+DLA + S + F+E +K ++ Q+L G
Sbjct: 193 D-HPNVIKLEGL--VTSRMSSSLYLVFRYMDHDLAGLAASPEIKFTEQQVKCYMKQLLSG 249
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+++ H+ V+HRD+K N+L G ++I DFGLA S +TN V T W
Sbjct: 250 LEHCHNRGVLHRDIKGSNLLIDDGGVLRIGDFGLATFFDASKR------QEMTNRVVTLW 303
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
YR+PEL+ YS VD+W+ GCILAE + + G + + Q+ I K+ G+P +
Sbjct: 304 YRSPELLHGVVEYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYW 363
Query: 310 RTYG-SSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDH 368
+ S PQYK+ E++ S EA+ L++ L+ +P R T + L
Sbjct: 364 KKIRLPSTHKHAHHKPLPQYKRR-IREVYKDFSPEALSLLDTLLALDPAERQTATDVLMS 422
Query: 369 PF 370
F
Sbjct: 423 DF 424
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 129 bits (325), Expect = 7e-30
Identities = 91/300 (30%), Positives = 150/300 (49%), Gaps = 18/300 (6%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
+E L +G+G+Y +V A D T ++ +A+KKV + ++ RE+ +
Sbjct: 147 FEKLDKIGQGTYSSVYKARDL--ETGKI-VAMKKVRFVNMDPESVRFMAREILILRKLD- 202
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHFLYQILCGMK 191
H N++ L L V LY E +++DLA + + + FSE IK ++ Q+ G++
Sbjct: 203 HPNVMKLEGL--VTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQLFRGLE 260
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
+ H ++HRD+K N+L + G +KI DFGLA G +T+ V T WYR
Sbjct: 261 HCHRRGILHRDIKGSNLLINNEGVLKIGDFGLAN------FYRGDGDLQLTSRVVTLWYR 314
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIRT 311
APEL+L Y ++D+W+ GCIL E + KP+ G + Q+ +I K+ G+P +
Sbjct: 315 APELLLGATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSE----D 370
Query: 312 YGSSRCYDIFSTSKPQYKKTP-WCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
Y + ++ KP + P E F + S A+ L+ +L+ PE R + L F
Sbjct: 371 YWRRATLPLATSFKPSHPYKPVLAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEF 430
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 129 bits (324), Expect = 9e-30
Identities = 104/370 (28%), Positives = 187/370 (50%), Gaps = 39/370 (10%)
Query: 47 NNHIYVDPILTKRSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKK 106
+ H+ ++ KR S + V ++ LQ++G GS+G V AV + N + +AIKK
Sbjct: 11 SEHVTFHTVMAKRGTGSKLDREVEIQFTNLQLIGTGSFGAVYKAVLREN---DEPIAIKK 67
Query: 107 VTSIFTREILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLAR 166
+ ++ + REL M + H NI+ L+ ++ +E + L E + DLA
Sbjct: 68 I------KVDDRFKSRELTIM-HEMDHPNIIRLLYYYVMQQE--NCLNFVMEFMPKDLAY 118
Query: 167 V----IHSNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSIT-GEIKICDF 221
V H++ + IK +++Q+L G+ ++H +++HRD+KP N+L + G +KICDF
Sbjct: 119 VHRQFAHNDKQMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDF 178
Query: 222 GLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGR 281
G A+ + + +IT Y+ +R+YRAPELI K Y S+D W+VG ++ E
Sbjct: 179 GSAKRLEKN-------EPNIT-YICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHN 230
Query: 282 KPVFMGNDSLHQVMEIQ-KILGTPKQIVIRTYGSSRCYDIFST-SKPQYKKTPWCEIFPY 339
P+F+ DS ++ +Q K GTP + + + + + T + +K I
Sbjct: 231 SPIFLA-DSAVDILALQIKAFGTPSKEDMAKWNYEYVHIPYDTITGVGIQKF----IGRK 285
Query: 340 ASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRN-----PEAEPICPHGPFDFTYEK 394
S ++L+ L+ +P+ R+ EAL P+ +R+ P PI P FD+ +
Sbjct: 286 LSLSTLELLNSLMKMDPKLRIKPYEALTLPYFDDLRDPHYKLPSGAPIPP--LFDWLERE 343
Query: 395 HLYSMERLRE 404
++ + E +++
Sbjct: 344 YIANHEIIKD 353
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 129 bits (324), Expect = 9e-30
Identities = 85/318 (26%), Positives = 168/318 (52%), Gaps = 31/318 (9%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y++++ LG+G Y V A+ N T + +K + + K+ RE+K + +G
Sbjct: 37 YQLVRKLGRGKYSEVFEAI---NITTTEKCVVK-----ILKPVKKKKIKREIKILENLRG 88
Query: 133 HRNIVSLIDLEIVNEEPYSGL--YCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGM 190
NI++L+ V ++P S ++ + + D ++ + +++ I+++L+++L +
Sbjct: 89 GTNIITLL---AVVKDPVSRTPALIFEHVNNTDFKQLYQT---LTDYEIRYYLFELLKAL 142
Query: 191 KYIHSADVIHRDLKPGNILCSITG-EIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
Y HS ++HRD+KP N++ ++++ D+GLA P VA+R+
Sbjct: 143 DYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPG--------QEYNVRVASRY 194
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRK-PVFMGNDSLHQVMEIQKILGTPK-QI 307
++ PEL++ ++ Y S+DMW++GC+LA RK P F G+D+ Q++ I K+LGT +
Sbjct: 195 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYA 254
Query: 308 VIRTYG---SSRCYDIFST-SKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVE 363
+ Y R +DI S+ ++++ + S EA+D +++L+ ++ RLT
Sbjct: 255 YLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAR 314
Query: 364 EALDHPFLQQVRNPEAEP 381
EA+ HP+ + N + P
Sbjct: 315 EAMAHPYFLPIVNGQMNP 332
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 128 bits (321), Expect = 2e-29
Identities = 98/321 (30%), Positives = 161/321 (49%), Gaps = 34/321 (10%)
Query: 68 SVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFM 127
S+ Y +++ +G G++G+V A K P+ EV +AIK + + R +RE+ +
Sbjct: 31 SIDEVYNVVRKVGDGTFGSVYLATTK-TPSKEV-VAIKSMKKKLAKVSDATR-LREVHSL 87
Query: 128 SYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS--NVLFSEFHIKHFLYQ 185
+ NIV++ DL I + + L+ E +D +L ++I + N + ++ + Q
Sbjct: 88 LRLSENENIVNIFDLYI---DQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQ 144
Query: 186 ILCGMKYIHSADVIHRDLKPGNILCSITGE-----IKICDFGLARGIS--PSFTVAGGIS 238
I G+ +IH+ HRD+KP NIL S + +KI DFGLAR I+ P +T
Sbjct: 145 IFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYT------ 198
Query: 239 NHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQ 298
YV+TRWYRAPEL+L YS VD++A GC+ E +P+F GND Q+ ++
Sbjct: 199 ----EYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMC 254
Query: 299 KILGTPKQIVIRTYG--------SSRCYDIFSTSKPQYKKTPWCEIF-PYASSEAVDLME 349
+ILG+P + T + + S P+ + ++F P + ++
Sbjct: 255 EILGSPDEQSQNTGDKGGGIWDRAELLANKLGISLPKMAPLDFGDLFSPPWNLAFASMLS 314
Query: 350 RLIDWNPEARLTVEEALDHPF 370
+L+ W+P R T E LD F
Sbjct: 315 QLLKWDPAKRPTAEMCLDLEF 335
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 127 bits (320), Expect = 3e-29
Identities = 98/309 (31%), Positives = 145/309 (46%), Gaps = 36/309 (11%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKV---------TSIFTREILLKRAIRE 123
YE L+ +G+G+Y V A D + +A+KKV REIL+ R +
Sbjct: 114 YEKLEKIGQGTYSNVYKAKDLLSGKI---VALKKVRFDNLEAESVKFMAREILVLRRLN- 169
Query: 124 LKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL-FSEFHIKHF 182
H N++ L L V LY E +++DL+ + + L F +K F
Sbjct: 170 ---------HPNVIKLQGL--VTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCF 218
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
+ Q+L G+++ HS V+HRD+K N+L G +KI DFGLA P +T
Sbjct: 219 MKQLLSGLEHCHSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQ------KQTMT 272
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+ V T WYR PEL+L Y VD+W+ GCI+AE KPV G + Q+ +I K+ G
Sbjct: 273 SRVVTLWYRPPELLLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCG 332
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYK-KTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
+P + Y + KPQ+ K E F + +V L+E L+ +P R T
Sbjct: 333 SPSDSYWKKYRLPNA----TLFKPQHPYKRCVAEAFNGFTPSSVHLVETLLTIDPADRGT 388
Query: 362 VEEALDHPF 370
AL+ F
Sbjct: 389 STSALNSEF 397
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 126 bits (317), Expect = 6e-29
Identities = 90/322 (27%), Positives = 159/322 (48%), Gaps = 53/322 (16%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
Y++++ LG+G Y V V +K V K+ RE+K + +G
Sbjct: 38 YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKK--------KKIKREIKILENLRG 89
Query: 133 HRNIVSLIDL-------------EIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHI 179
NI++L+D+ E VN + LY Q L DYD I
Sbjct: 90 GTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLY--QTLSDYD---------------I 132
Query: 180 KHFLYQILCGMKYIHSADVIHRDLKPGNILCSITG-EIKICDFGLARGISPSFTVAGGIS 238
+++LY++L + + HS ++HRD+KP N++ E+++ D+GLA P
Sbjct: 133 RYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPR-------- 184
Query: 239 NHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRK-PVFMGNDSLHQVMEI 297
VA+R+++ PEL++ ++ Y S+DMW++GC+LA RK P F G+D+ Q++ I
Sbjct: 185 QDYNVRVASRYFKGPELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRI 244
Query: 298 QKILGTPK--QIVIRTY--GSSRCYDIFST-SKPQYKKTPWCEIFPYASSEAVDLMERLI 352
K+LGT + + + R + R DI S+ ++++ E + EA+D +++L+
Sbjct: 245 AKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLL 304
Query: 353 DWNPEARLTVEEALDHPFLQQV 374
++ RLT +EA+ H + + V
Sbjct: 305 RYDHAERLTAQEAMGHEYFRPV 326
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 126 bits (317), Expect = 6e-29
Identities = 87/317 (27%), Positives = 165/317 (51%), Gaps = 33/317 (10%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE+++ +G+G Y S V +G + + + K+ + + K+ RE+K + G
Sbjct: 34 YEVVRKVGRGKY----SEVFEGKNVNTNERCVIKIL----KPVKKKKIKREIKILQNLCG 85
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKY 192
NIV L D IV +E E V+ +V++ + +++ I++++Y++L + +
Sbjct: 86 GPNIVKLYD--IVRDEHSKTPSLVFEFVNSVDFKVLYPTL--TDYDIRYYIYELLKALDF 141
Query: 193 IHSADVIHRDLKPGNILCSIT-GEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
HS ++HRD+KP N++ ++++ D+GLA P VA+R+++
Sbjct: 142 CHSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPG--------KEYNVRVASRYFK 193
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRK-PVFMGNDSLHQVMEIQKILGTPKQIVIR 310
PEL++ + Y S+DMW++GC+ A RK P F G+D+ Q+++I K+LGT + +
Sbjct: 194 GPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTNE---LD 250
Query: 311 TYGSSRCYDI---FSTSKPQYKKTPWCEIF-----PYASSEAVDLMERLIDWNPEARLTV 362
Y + D+ ++ PW + S EA+D +++L+ ++ + RLT
Sbjct: 251 HYLNKYQLDLDPQLEALVGRHVPKPWSKFINADNQHLVSPEAIDFLDKLLQYDHQDRLTA 310
Query: 363 EEALDHPFLQQVRNPEA 379
EA+DHP+ QV+ E+
Sbjct: 311 REAMDHPYFAQVKAAES 327
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 126 bits (316), Expect = 7e-29
Identities = 101/322 (31%), Positives = 150/322 (46%), Gaps = 38/322 (11%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS----------IFTREILLKRAI 121
RYE + +G G+YGTV A D + H V L +V + RE+ L R +
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDP-HSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 122 RELKFMSYFKGHRNIVSLIDLEIVNEEPYS-GLYCYQELVDYDLARVIHSNV---LFSEF 177
+ H N+V L+D+ + + E VD DL + L +E
Sbjct: 64 EAFE-------HPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAET 116
Query: 178 HIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGI 237
IK + Q L G+ ++H+ ++HRDLKP NIL + G +K+ DFGLAR S
Sbjct: 117 -IKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMA----- 170
Query: 238 SNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEI 297
+T V T WYRAPE++L Y+ VDMW+VGCI AE + RKP+F GN Q+ +I
Sbjct: 171 ---LTPVVVTLWYRAPEVLL-QSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKI 226
Query: 298 QKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPE 357
++G P + R + + P P + P L+ ++ +NP
Sbjct: 227 FDLIGLPPE-----DDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPH 281
Query: 358 ARLTVEEALDHPFLQQVR-NPE 378
R++ AL H +L + NPE
Sbjct: 282 KRISAFRALQHSYLHKDEGNPE 303
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 125 bits (315), Expect = 1e-28
Identities = 88/309 (28%), Positives = 142/309 (45%), Gaps = 37/309 (11%)
Query: 73 YEILQVLGKGSYGTV----------VSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIR 122
YE + + GS+G V V A+ + NP+ + + ++ RE+++ + IR
Sbjct: 26 YEKVCRISSGSFGNVYRVRRKTDNRVFALKRMNPS--MCYDTNGFSILYIREVMILKHIR 83
Query: 123 ELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHF 182
HRNI+ + E+V + + E D DL VIHS +
Sbjct: 84 ----------HRNIMEIE--EVVEGCEINDFFIVMECCDTDLRSVIHSVGKIGMKAARFL 131
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
Q+L G+K++H A ++HRDLKP NIL G ++I DFGLAR I + +T
Sbjct: 132 TCQMLKGLKFLHGAGIVHRDLKPSNILLMRDGGLRIADFGLARAIE----------SQMT 181
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
N V T WYR E++L + Y +S+DMW+VGC++ E +P+ G + Q+ I ++LG
Sbjct: 182 NLVVTLWYRPIEILLGSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLG 241
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
P +I +P + + F EA + L+ ++P R T
Sbjct: 242 YPTDADFEGLDLPHFKNI---RRPSTFEASFEGDFECYGEEAASFVRNLLSFDPRKRCTA 298
Query: 363 EEALDHPFL 371
+ L F+
Sbjct: 299 SQGLCSGFV 307
>SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 332
Score = 125 bits (313), Expect = 2e-28
Identities = 94/324 (29%), Positives = 162/324 (49%), Gaps = 43/324 (13%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
F YEI++ +G+G Y V ++ N + + +K V K+ RE+K
Sbjct: 37 FGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVK--------YKKIKREIKI 88
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
+ G NI+SL+D+ E L E VD R ++ + S++ I+++ Y++
Sbjct: 89 LQNLAGGPNIISLLDIVRDPESKTPSLIF--EFVDNIDFRTLYPTL--SDYDIRYYSYEL 144
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITG-EIKICDFGLARGISPSFTVAGGISNHITNYV 245
L + + HS ++HRD+KP N++ ++++ D+GLA F AG N V
Sbjct: 145 LKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAE-----FYHAGMEYNV---RV 196
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFM-GNDSLHQVMEIQKILGTP 304
A+R+++ PEL++ + Y S+D+W+ G + A +K F G D+ Q+++I K+LGT
Sbjct: 197 ASRYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTD 256
Query: 305 K--------QIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-----PYASSEAVDLMERL 351
+ QIV+ R YD QY K W A+ EA+DL+ RL
Sbjct: 257 ELFAYVQKYQIVL-----DRQYD---NILGQYPKRDWYSFVNRDNRSLANDEAIDLLNRL 308
Query: 352 IDWNPEARLTVEEALDHPFLQQVR 375
+ ++ + RLT +EA+ HP+ Q ++
Sbjct: 309 LRYDHQERLTCQEAMAHPYFQVLK 332
>At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 432
Score = 125 bits (313), Expect = 2e-28
Identities = 79/320 (24%), Positives = 167/320 (51%), Gaps = 27/320 (8%)
Query: 67 FSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKF 126
+ V YE+++ +G+G Y V + + T + IK + + K+ RE+K
Sbjct: 126 WGVQDDYEVVRKVGRGKYSEVFEGI---HATDNEKCVIK-----ILKPVKKKKIKREIKI 177
Query: 127 MSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQI 186
+ G NIV L+D+ + +++ + ++ + + D +V++ + S++ ++++++++
Sbjct: 178 LQNLCGGPNIVKLLDI-VRDQQSKTPSLIFEHVNNKDF-KVLYPTL--SDYDVRYYIFEL 233
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITG-EIKICDFGLARGISPSFTVAGGISNHITNYV 245
L + + HS ++HRD+KP N++ ++++ D+GLA P V
Sbjct: 234 LKALDFCHSRGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPG--------KEYNVRV 285
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRK-PVFMGNDSLHQVMEIQKILGTP 304
A+R+++ PEL++ + Y S+D+W++GC+ A RK P F G+D+ Q+++I K+LGT
Sbjct: 286 ASRYFKGPELLVDLQDYDYSLDLWSLGCMFAGMIFRKEPFFYGHDNYDQLVKIAKVLGTD 345
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIF-----PYASSEAVDLMERLIDWNPEAR 359
+ ++ ++ + PW + A EAVD +++L+ ++ + R
Sbjct: 346 ELNAYLNKYRIELDPNLTSLVGRHSRKPWTKFINSENQHLAVPEAVDFVDKLLRYDHQER 405
Query: 360 LTVEEALDHPFLQQVRNPEA 379
T +EA+ HP+ +RN E+
Sbjct: 406 PTAKEAMAHPYFYPIRNAES 425
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 125 bits (313), Expect = 2e-28
Identities = 97/308 (31%), Positives = 151/308 (48%), Gaps = 40/308 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKV---------TSIFTREILLKRAIRE 123
+E L+++G+G+Y +V A D T+++ +A+KKV REI++ R +
Sbjct: 146 FEKLEMIGQGTYSSVYRARDL--ETNQI-VALKKVRFANMDPESVRFMAREIIILRRLN- 201
Query: 124 LKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHF 182
H N++ L L I + +Y E +D+DLA + + + FS+
Sbjct: 202 ---------HPNVMKLEGLII--SKASGSMYLIFEYMDHDLAGLASTPGIKFSQAQ---- 246
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
Q+L G+++ HS V+HRD+K N+L +KI DFGL+ G +T
Sbjct: 247 --QLLLGLEHCHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSN------FYRGQRKQPLT 298
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+ V T WYR PEL+L Y +VD+W+ GCILAE + KP+ G + Q+ +I K+ G
Sbjct: 299 SRVVTLWYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCG 358
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
+P + R R IF P YK+ + F S A+ L+E L+ P+AR T
Sbjct: 359 SPSEEYWRR-SRLRHATIFKPQHP-YKRCV-ADTFKDLPSSALALLEVLLAVEPDARGTA 415
Query: 363 EEALDHPF 370
AL F
Sbjct: 416 SSALQSEF 423
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 124 bits (312), Expect = 2e-28
Identities = 81/313 (25%), Positives = 157/313 (49%), Gaps = 27/313 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YE+++ +G+G Y V ++ + + +K V K+ RE+K + G
Sbjct: 34 YEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKK--------KKIRREIKILQNLCG 85
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKY 192
NIV L+D +V ++ E V+ +V++ + +++ I++++Y++L + +
Sbjct: 86 GPNIVKLLD--VVRDQHSKTPSLIFEYVNSTDFKVLYPTL--TDYDIRYYIYELLKALDF 141
Query: 193 IHSADVIHRDLKPGNILCSIT-GEIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
HS ++HRD+KP N++ ++++ D+GLA P VA+R+++
Sbjct: 142 CHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPG--------KEYNVRVASRYFK 193
Query: 252 APELILSHKRYSKSVDMWAVGCILAEFYGRK-PVFMGNDSLHQVMEIQKILGTPKQIVIR 310
PEL++ + Y S+DMW++GC+ A RK P F G+D+ Q+++I K+LGT +
Sbjct: 194 GPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYL 253
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIF-----PYASSEAVDLMERLIDWNPEARLTVEEA 365
++ + PW + S EA+D +++L+ ++ + RLT +EA
Sbjct: 254 NKYQLELDPQLEALVGRHSRKPWSKFINADNQHLVSPEAIDFLDKLLRYDHQDRLTAKEA 313
Query: 366 LDHPFLQQVRNPE 378
+ H + QVR E
Sbjct: 314 MAHAYFAQVRAAE 326
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 124 bits (312), Expect = 2e-28
Identities = 98/326 (30%), Positives = 153/326 (46%), Gaps = 37/326 (11%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKV---------TSIFTREILLKRAIRE 123
+E L+ +G+G+Y V AV+ T + +A+KKV REIL+ R +
Sbjct: 121 FEKLEKIGQGTYSNVFRAVE--TETGRI-VALKKVRFDNFEPESVKFMAREILILRRLN- 176
Query: 124 LKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHF 182
H NI+ L L + + + E +++DL ++ S ++ F+ IK +
Sbjct: 177 ---------HPNIIKLEGL--ITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCY 225
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
+ Q+L G+ + HS V+HRD+K N+L S G +K+ DFGLA + S G +T
Sbjct: 226 MKQLLSGLDHCHSRGVMHRDIKGSNLLLSNEGILKVADFGLANFSNSS----GHKKKPLT 281
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+ V T WYR PEL+L Y SVD+W+VGC+ AE KP+ G + Q+ +I K+ G
Sbjct: 282 SRVVTLWYRPPELLLGATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCG 341
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWC-EIFPYASSEAVDLMERLIDWNPEARLT 361
+P + Y KPQ E S ++L+E L+ +P R T
Sbjct: 342 SPPE----DYWKKSKLPHAMLFKPQQTYDSCLRETLKDLSETEINLIETLLSIDPHKRGT 397
Query: 362 VEEALDHPFLQQ---VRNPEAEPICP 384
AL + +P + PI P
Sbjct: 398 ASSALVSQYFTTKPFACDPSSLPIYP 423
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 124 bits (312), Expect = 2e-28
Identities = 93/312 (29%), Positives = 156/312 (49%), Gaps = 28/312 (8%)
Query: 70 PGRYEILQVLGKGSYGTVVSAVD--KGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFM 127
P Y+ L ++G+G+YGTV A D GN +A+KKV + +RE+ +
Sbjct: 23 PFNYQELNIIGEGAYGTVYRARDVITGNI-----VALKKVRISLNENGVPMSTLREISLL 77
Query: 128 SYFKG--HRNIVSLIDL-EIVNEEPYSGLYCYQELVDYDLARVIHS--NVLFSEFHIKHF 182
H NIV L ++ + + + + E V+ DL+ +I S I+
Sbjct: 78 KQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRL 137
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
++L G+ ++HS +IHRDLKP N+L S G +KI DFGLA+ G +T
Sbjct: 138 SRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK--------TYGSEMKLT 189
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+ V T WYRAPE++L+ + Y+ +VD+W+ CI+ E + R+ +F G +Q+ I ++ G
Sbjct: 190 SVVVTLWYRAPEVLLA-QPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTG 248
Query: 303 TP-KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLT 361
P +Q +T S + F P+ K + P+ A DL+ +++ ++ R +
Sbjct: 249 RPTEQQWPQTI--SVALEHFPQRHPKRPK----DFCPHLCKYADDLLNKMLSYDLHLRPS 302
Query: 362 VEEALDHPFLQQ 373
L+H + QQ
Sbjct: 303 ALACLEHDYFQQ 314
>YOR061w [TDK] KOG0668 Casein kinase II alpha subunit
Length = 339
Score = 124 bits (310), Expect = 4e-28
Identities = 85/307 (27%), Positives = 160/307 (51%), Gaps = 28/307 (9%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKG 132
YEI+ +G+G Y V S G Q + KV + + +K+ RELK ++ G
Sbjct: 50 YEIINKIGRGKYSEVFS----GRCIVNNQKCVIKVL----KPVKMKKIYRELKILTNLTG 101
Query: 133 HRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMKY 192
N+V L D+ + + + ++E+ + D + + F I+++ Q+L + Y
Sbjct: 102 GPNVVGLYDI-VQDADSKIPALIFEEIKNVDFRTLYPT---FKLPDIQYYFTQLLIALDY 157
Query: 193 IHSADVIHRDLKPGNILCSITG-EIKICDFGLARGISPSFTVAGGISNHITNYVATRWYR 251
HS ++HRD+KP N++ T ++++ D+GLA P G+ ++ VA+R+++
Sbjct: 158 CHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHP------GVDYNVR--VASRYHK 209
Query: 252 APELILSHKRYSKSVDMWAVGCILAEF-YGRKPVFMGNDSLHQVMEIQKILGTPKQI-VI 309
PEL+++ +Y S+D+W+VGC+LA + ++P F G+ + Q+++I +LGT + + +
Sbjct: 210 GPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYL 269
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIF----PYASSEAVDLMERLIDWNPEARLTVEEA 365
YG + + + K W A E VDL++ L+ ++ + RLT +EA
Sbjct: 270 GKYGLHLPSE-YDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEA 328
Query: 366 LDHPFLQ 372
+DH F +
Sbjct: 329 MDHKFFK 335
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 123 bits (308), Expect = 6e-28
Identities = 101/333 (30%), Positives = 160/333 (47%), Gaps = 45/333 (13%)
Query: 62 YSPANFSVPGRYEI-----------LQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSI 110
Y P ++P + E+ + LG+GSY TV K + + +A+K++
Sbjct: 86 YDPNTITLPAKEEVTPQDVNDLYKRIDKLGEGSYATVYKCESKLDGSI---VALKEIKLQ 142
Query: 111 FTREILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS 170
F +E L AIRE + + H NIVSL D+ + + L E + DL++ +
Sbjct: 143 F-QEGLPFTAIREASLLRNLR-HANIVSLHDIFYQHHQ----LTFVFEYMKMDLSKYLEQ 196
Query: 171 NVL-FSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS- 228
NV IK L+Q+L G+ + H ++HRDLKP N+L G +K+ DFGLAR S
Sbjct: 197 NVYGLDSIDIKLLLFQLLRGLDFCHRKKILHRDLKPQNLLLDEDGVLKLADFGLARAKSV 256
Query: 229 PSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGN 288
PS T ++ V T WYR P++++ YS S+DMW VGCI AE +F G+
Sbjct: 257 PSRT--------YSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAALFPGS 308
Query: 289 DSLH------QVMEIQKILGTPKQIVIRTYGSSRCY--DIFSTSKPQYKKTPWCEIFPYA 340
H Q+ I I GTP + + Y ++F P+Y++ + + P
Sbjct: 309 KDSHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLPGYTPELF----PRYRELSFIAVNPMF 364
Query: 341 S---SEAVDLMERLIDWNPEARLTVEEALDHPF 370
+ +L+ L+ PE+R++ A+ HP+
Sbjct: 365 TKILKTGQELLGMLLQLRPESRVSAASAMLHPY 397
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 122 bits (306), Expect = 1e-27
Identities = 77/244 (31%), Positives = 125/244 (50%), Gaps = 25/244 (10%)
Query: 158 ELVDYDLARVIHSNV-----LFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSI 212
E ++DL ++IH + + ++ ++Q+L G+ Y+H V+HRDLKP NI+ +I
Sbjct: 237 EYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTI 296
Query: 213 TGEIKICDFGLARGISPSF-TVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAV 271
G +KI D GLAR T+ G V T WYRAPEL+L + Y+ +VD+W+V
Sbjct: 297 DGCVKIGDLGLARKFHNMLQTLYTG-----DKVVVTIWYRAPELLLGARHYTPAVDLWSV 351
Query: 272 GCILAEFYGRKPVFMGNDS-----------LHQVMEIQKILGTPKQIVIRTYGSSRCYDI 320
GCI AE G +P+F G ++ ++Q+ I ++LGTP Q + YD
Sbjct: 352 GCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQ 411
Query: 321 FSTSKPQYKK--TPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRNPE 378
T P+Y+ W A+ L+ L++++P R+ AL+H + + P
Sbjct: 412 I-TKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPV 470
Query: 379 AEPI 382
+E +
Sbjct: 471 SENV 474
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 122 bits (306), Expect = 1e-27
Identities = 93/311 (29%), Positives = 152/311 (47%), Gaps = 18/311 (5%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+YE L G+GSYG V +K T +A+KK ++ K A+RE++ + K
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNK---TSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLK 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGL-YCYQELVDYDLARV---IHSNVLFSEFHIKHFLYQIL 187
H N+V+LI++ + + YC L++ +L R + S+ + ++
Sbjct: 60 -HPNLVNLIEVFRRKRKMHLVFEYCDHTLLN-ELERNPNGMDSDSIVGRLRSVADRSRLA 117
Query: 188 CGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVAT 247
I IHRD+KP NIL + G IKICDFG A+ + P + T+YVAT
Sbjct: 118 PKNNQIMILQCIHRDIKPENILITKQGIIKICDFGFAQILIPG--------DAYTDYVAT 169
Query: 248 RWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
RWYRAPEL++ +Y SVD+WA+GC+ AE +P++ G + Q+ I + LG
Sbjct: 170 RWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPR 229
Query: 308 VIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALD 367
+ S+ + S +P+ +T E F A++ M+ + NP+ RLT + L+
Sbjct: 230 HQSIFKSNGFFHGISIPEPEDMET-LEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLE 288
Query: 368 HPFLQQVRNPE 378
+ + +
Sbjct: 289 SSYFDSFQEAQ 299
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 122 bits (306), Expect = 1e-27
Identities = 78/239 (32%), Positives = 133/239 (55%), Gaps = 25/239 (10%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RY + ++G G+YG V A+D T E ++A+K++ + +E + A+RE+ +
Sbjct: 3 RYILGALIGSGTYGEVYEAID--TETKE-KVALKRIR-LNEKEGMPGTALREISILKKLS 58
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGMK 191
HRNI+SL+ I++ + L +DY+L + I N + +I + Q++CG+
Sbjct: 59 -HRNIISLVS--IIHTDAL--LTMVFPFIDYELKKYIGMN---TGKNIMELVNQLICGVH 110
Query: 192 YIHSADVIHRDLKPGNILCSITGEIKICDFGLARGIS---PSFTVAGGISNHITNYVATR 248
Y+H +V+HRDLKP NIL + G +KI DFGL+R + P + ++ V T
Sbjct: 111 YLHRMNVVHRDLKPQNILVTSDGVLKIADFGLSRSLEIRVPPY----------SSEVVTL 160
Query: 249 WYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQI 307
WYR+PEL++ Y VD+W++GCI+ E +P+F G +Q+ I++ GT + +
Sbjct: 161 WYRSPELLMGSTSYRFYVDIWSLGCIIYEMITLEPLFPGESKENQLTLIRRKAGTRRSL 219
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 122 bits (306), Expect = 1e-27
Identities = 80/244 (32%), Positives = 129/244 (52%), Gaps = 30/244 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKV---------TSIFTREILLKRAIRE 123
+E L+ +G+G+Y +V A + T + +A+KKV REIL+ R +
Sbjct: 131 FEKLEKIGQGTYSSVFRA--RETETGRI-VALKKVRFDNFEPESVRFMAREILILRKLN- 186
Query: 124 LKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHS-NVLFSEFHIKHF 182
H NI+ L IV + ++ E +++DL ++ S ++ F+ IK +
Sbjct: 187 ---------HPNIIKLEG--IVTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQIKCY 235
Query: 183 LYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHIT 242
+ Q+L G+ + H+ V+HRD+K N+L + G +K+ DFGLA +F A G +T
Sbjct: 236 MKQLLSGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLA-----NFCNASGNKQPLT 290
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+ V T WYR PEL+L Y SVD+W+VGC+ AE KPV G + Q+ +I K+ G
Sbjct: 291 SRVVTLWYRPPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCG 350
Query: 303 TPKQ 306
+P +
Sbjct: 351 SPPE 354
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 120 bits (302), Expect = 3e-27
Identities = 89/320 (27%), Positives = 151/320 (46%), Gaps = 61/320 (19%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RY ++++G+GS+G VV +D + LKR ++ ++ +
Sbjct: 55 RYRYVEMIGRGSFGVVVKIMDDRH-----------------NFFALKRVYQDRRYHNREL 97
Query: 132 G------HRNIVSLIDLEIVNEEPYSGLYC--YQELVDYDLARVIHSNVLFSEFHIKHFL 183
G H NIV L+ ++ SG Y + V +L I +N I+
Sbjct: 98 GILMEVDHPNIVRLVSY-FHTDKTSSGAYLNIITDFVGMNLEEYIKANRGVETEEIRSVY 156
Query: 184 YQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITN 243
QIL G++Y+H ++ HRD+KP NIL G +KICD G A+ I +IT
Sbjct: 157 RQILEGLRYLHEKNICHRDMKPSNILIDTNGLVKICDLGSAKVIKSG-------ERNIT- 208
Query: 244 YVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDS---LHQVMEIQKI 300
Y+ +R+YRAPE +L +K Y +D+W+VGC++AEF P+F G+ S L++++EI ++
Sbjct: 209 YICSRFYRAPENLLDYKEYDFKIDIWSVGCVIAEFRHPGPIFKGDTSGSTLNRILEIVRV 268
Query: 301 -------LGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLID 353
LG K + + G + + F ++ + ++++E+ +
Sbjct: 269 TSDDLIGLGCLKPDLKQGVGIRKYLEAF-----------------FSDPDLLEVLEKSLA 311
Query: 354 WNPEARLTVEEALDHPFLQQ 373
++P R T E L F QQ
Sbjct: 312 FSPCKRSTASELLRKQFFQQ 331
>CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 489
Score = 120 bits (302), Expect = 3e-27
Identities = 78/248 (31%), Positives = 124/248 (49%), Gaps = 21/248 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEV----------QLAIKKVTSIFTREILLKRAIR 122
YE L +G+G++G V+ N EV +A+KK+ +E A+R
Sbjct: 85 YEKLNKIGQGTFGQVLQGRKSRNS--EVFKARCKNTGRMVALKKILMENEKEGFPITALR 142
Query: 123 ELKFMSYFKGHRNIVSLIDLEIVNEEPYSG------LYCYQELVDYDLARVIHS-NVLFS 175
E+K + K H NI LI++ +G Y L +DLA ++ + + S
Sbjct: 143 EVKMLEQLK-HPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMS 201
Query: 176 EFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAG 235
HIK + ++ G+ +H + ++HRD+K N+L S G +K+ DFGLAR AG
Sbjct: 202 LVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAG 261
Query: 236 GISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVM 295
+ TN V T WYR PEL+L ++Y +D+W GCI+AE + R+P+ G+ Q+
Sbjct: 262 PRPLY-TNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQ 320
Query: 296 EIQKILGT 303
I + G+
Sbjct: 321 LISGLCGS 328
>CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 456
Score = 120 bits (302), Expect = 3e-27
Identities = 78/248 (31%), Positives = 124/248 (49%), Gaps = 21/248 (8%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEV----------QLAIKKVTSIFTREILLKRAIR 122
YE L +G+G++G V+ N EV +A+KK+ +E A+R
Sbjct: 85 YEKLNKIGQGTFGQVLQGRKSRNS--EVFKARCKNTGRMVALKKILMENEKEGFPITALR 142
Query: 123 ELKFMSYFKGHRNIVSLIDLEIVNEEPYSG------LYCYQELVDYDLARVIHS-NVLFS 175
E+K + K H NI LI++ +G Y L +DLA ++ + + S
Sbjct: 143 EVKMLEQLK-HPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMS 201
Query: 176 EFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAG 235
HIK + ++ G+ +H + ++HRD+K N+L S G +K+ DFGLAR AG
Sbjct: 202 LVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAG 261
Query: 236 GISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVM 295
+ TN V T WYR PEL+L ++Y +D+W GCI+AE + R+P+ G+ Q+
Sbjct: 262 PRPLY-TNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQ 320
Query: 296 EIQKILGT 303
I + G+
Sbjct: 321 LISGLCGS 328
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 120 bits (300), Expect = 5e-27
Identities = 86/313 (27%), Positives = 144/313 (45%), Gaps = 44/313 (14%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RY+ ++ LG+G + V A D + IK + ++ + + AIRE+K +
Sbjct: 4 RYDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIH 63
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSN-VLFSEFHIKHFLYQILCGM 190
H NI+ L D ++ + + + +D DL VI ++ HIK+ Q+L G+
Sbjct: 64 -HDNIIGLRD--VIGHR--TSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGL 118
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
+++H ++HRDLKP N+L + G V TRWY
Sbjct: 119 EFLHVHWILHRDLKPNNLLMNKMGR-----------------------------VVTRWY 149
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
RAPEL+ + Y +D+W+VGCI+AE R P+F G + Q+++I ILG P
Sbjct: 150 RAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTP---E 206
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPF 370
T+ + + + KPQ + F A + +DLM + ++P RLT ++L +
Sbjct: 207 TWPNMTEMNSYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEY 266
Query: 371 LQQVRNPEAEPIC 383
+ +P C
Sbjct: 267 FR------TQPFC 273
>Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 520
Score = 119 bits (299), Expect = 7e-27
Identities = 91/325 (28%), Positives = 156/325 (48%), Gaps = 32/325 (9%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RYE+L+ +GKGS+G V +D N V L I + F ++ L++ I E
Sbjct: 103 RYEVLETIGKGSFGQVAKCLDHKN-NELVALKIIRNKKRFHQQALMELKILEALRKKDKD 161
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQ-ELVDYDLARVIHSNVL--FSEFHIKHFLYQILC 188
N+V + D +C EL+ +L ++ +N FS ++ F +L
Sbjct: 162 NTYNVVHMKDFFYFRNH-----FCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLK 216
Query: 189 GMKYIHSADVIHRDLKPGNILCSITGE--IKICDFGLARGISPSFTVAGGISNHITNYVA 246
++ + +IH DLKP NI+ G+ +K+ DFG S + + Y+
Sbjct: 217 CLQMLSVEKIIHCDLKPENIVLYQKGQASVKVIDFG-----SSCYE-----HQKVYTYIQ 266
Query: 247 TRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQ 306
+R+YR+PE+IL H Y ++DMW++GCI AE Y P+F G + + Q+ I ++LG P
Sbjct: 267 SRFYRSPEVILGHP-YDVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLPPA 325
Query: 307 IVI------RTYGSSRCYDIFSTSKPQYKKTPWCE----IFPYASSEAVDLMERLIDWNP 356
I +T+ S+ + T+ K+ P + + + +D + R + W P
Sbjct: 326 GFIQTASRRQTFFDSKGFPKNITNNRGKKRYPDSKDLTMVLKTYDTSFLDFLRRCLVWEP 385
Query: 357 EARLTVEEALDHPFLQQVRNPEAEP 381
R+T ++AL H ++ Q RN + +P
Sbjct: 386 SLRMTPDQALKHAWIHQSRNLKPQP 410
>CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 796
Score = 119 bits (299), Expect = 7e-27
Identities = 98/339 (28%), Positives = 154/339 (44%), Gaps = 59/339 (17%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RYE+L+V+GKGS+G V+ A D ++ +A+K V + + ++A E++ + + +
Sbjct: 460 RYEVLKVIGKGSFGQVIKAFDH---KYQQYVALKLVRN---EKRFHRQADEEIRILDHLR 513
Query: 132 -----GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL--FSEFHIKHFLY 184
G NI+ ++D EL+ +L +I N FS ++ F Y
Sbjct: 514 RQDSDGTHNIIHMLDYFNFRNHKCITF----ELLSINLYELIKRNKFQGFSLMLVRKFAY 569
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGE--IKICDFGLARGISPSFTVAGGISNHIT 242
+L + + +IH DLKP N+L G IK+ DFG S F I
Sbjct: 570 SMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFG-----SSCFD-----DQRIY 619
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
Y+ +R+YRAPE+IL K Y +DMW++GCILAE P+ G D Q+ I ++LG
Sbjct: 620 TYIQSRFYRAPEVILGTK-YGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLG 678
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQY---------------------------KKTPWCE 335
P + T +R + I S P+Y W
Sbjct: 679 MPPPKSLETAKRARTF-ITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWST 737
Query: 336 IFPYASSEA-VDLMERLIDWNPEARLTVEEALDHPFLQQ 373
E VD ++R +DW+PE R+T +AL H +L++
Sbjct: 738 ALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHKWLRR 776
>CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 817
Score = 119 bits (299), Expect = 7e-27
Identities = 98/339 (28%), Positives = 154/339 (44%), Gaps = 59/339 (17%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RYE+L+V+GKGS+G V+ A D ++ +A+K V + + ++A E++ + + +
Sbjct: 460 RYEVLKVIGKGSFGQVIKAFDH---KYQQYVALKLVRN---EKRFHRQADEEIRILDHLR 513
Query: 132 -----GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL--FSEFHIKHFLY 184
G NI+ ++D EL+ +L +I N FS ++ F Y
Sbjct: 514 RQDSDGTHNIIHMLDYFNFRNHKCITF----ELLSINLYELIKRNKFQGFSLMLVRKFAY 569
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGE--IKICDFGLARGISPSFTVAGGISNHIT 242
+L + + +IH DLKP N+L G IK+ DFG S F I
Sbjct: 570 SMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFG-----SSCFD-----DQRIY 619
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
Y+ +R+YRAPE+IL K Y +DMW++GCILAE P+ G D Q+ I ++LG
Sbjct: 620 TYIQSRFYRAPEVILGTK-YGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLG 678
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQY---------------------------KKTPWCE 335
P + T +R + I S P+Y W
Sbjct: 679 MPPPKSLETAKRARTF-ITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWST 737
Query: 336 IFPYASSEA-VDLMERLIDWNPEARLTVEEALDHPFLQQ 373
E VD ++R +DW+PE R+T +AL H +L++
Sbjct: 738 ALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHKWLRR 776
>CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 508
Score = 119 bits (299), Expect = 7e-27
Identities = 98/339 (28%), Positives = 154/339 (44%), Gaps = 59/339 (17%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
RYE+L+V+GKGS+G V+ A D ++ +A+K V + + ++A E++ + + +
Sbjct: 166 RYEVLKVIGKGSFGQVIKAFDH---KYQQYVALKLVRN---EKRFHRQADEEIRILDHLR 219
Query: 132 -----GHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVL--FSEFHIKHFLY 184
G NI+ ++D EL+ +L +I N FS ++ F Y
Sbjct: 220 RQDSDGTHNIIHMLDYFNFRNHKCITF----ELLSINLYELIKRNKFQGFSLMLVRKFAY 275
Query: 185 QILCGMKYIHSADVIHRDLKPGNILCSITGE--IKICDFGLARGISPSFTVAGGISNHIT 242
+L + + +IH DLKP N+L G IK+ DFG S F I
Sbjct: 276 SMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFG-----SSCFD-----DQRIY 325
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
Y+ +R+YRAPE+IL K Y +DMW++GCILAE P+ G D Q+ I ++LG
Sbjct: 326 TYIQSRFYRAPEVILGTK-YGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLG 384
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQY---------------------------KKTPWCE 335
P + T +R + I S P+Y W
Sbjct: 385 MPPPKSLETAKRARTF-ITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWST 443
Query: 336 IFPYASSEA-VDLMERLIDWNPEARLTVEEALDHPFLQQ 373
E VD ++R +DW+PE R+T +AL H +L++
Sbjct: 444 ALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHKWLRR 482
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 117 bits (293), Expect = 3e-26
Identities = 94/339 (27%), Positives = 160/339 (46%), Gaps = 48/339 (14%)
Query: 79 LGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFKGHRNIVS 138
+G+G+YG V A K + + A+K++ L A RE+ + K H+N+++
Sbjct: 104 VGRGTYGHVYKAKWKETSDGK-EYALKQIDGTG----LSMSACREIALLRELK-HQNVIT 157
Query: 139 LIDLEIVNEEPYSGLYCYQELVDYDL---------ARVIHSNVLFSEFHIKHFLYQILCG 189
LI + + + + ++ + ++DL A+ V+ +K LYQIL G
Sbjct: 158 LIRVFLSHND--RKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDG 215
Query: 190 MKYIHSADVIHRDLKPGNILC----SITGEIKICDFGLARGISPSFTVAGGISNHITNYV 245
+ Y+HS V+HRDLKP NIL + G +KI D G AR + + V
Sbjct: 216 IHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDP----VV 271
Query: 246 ATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVF--------MGNDSLH-QVME 296
T WYRAPEL+L + Y+K++D+WA+GCI AE +P+F N H Q+
Sbjct: 272 VTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDR 331
Query: 297 IQKILGTPKQIVIRTYGSSRCYDIFSTSKPQYKKTPW--CEIFPY-------ASSEAVDL 347
I ++G P+ + + + T +K++ + C + Y S+A L
Sbjct: 332 IFNVMGFPQD---KDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHL 388
Query: 348 MERLIDWNPEARLTVEEALDHPFLQQVRNPEAEPI--CP 384
+++L+ +P R+T E+A+ + Q+ P + CP
Sbjct: 389 LQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQDVFAGCP 427
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 117 bits (292), Expect = 4e-26
Identities = 96/361 (26%), Positives = 165/361 (45%), Gaps = 70/361 (19%)
Query: 72 RYEILQVLGKGSYGTVVSAVDK------------------GNPTHEVQLAIKKVTSIFTR 113
RY++++ LG GS+G V A + P + Q I K +
Sbjct: 37 RYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAI 96
Query: 114 EILLKRA--------IRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLA 165
+ ++ + +RE+KF+ + +++ + ++ ++ E Y L+ E ++ +L
Sbjct: 97 KTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEV-FIDSENYQ-LHIVMECMEQNLY 154
Query: 166 RVI--HSNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILCSITGE-------- 215
+++ +FS +K L QIL G+K+IH + HRDLKP NIL + + +
Sbjct: 155 QMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMN 214
Query: 216 ---------IKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSV 266
IK+ DFGLAR + N T YV+TRWYR+PE++L YSK +
Sbjct: 215 QIGYQDNYVIKLADFGLARHVENK--------NPYTAYVSTRWYRSPEILLRSGYYSKPL 266
Query: 267 DMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP--KQIVIRTYGSSR------CY 318
D+WA GC+ E + +F G + + Q+ +I ++LGTP + + T +
Sbjct: 267 DIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTNHITAPPPGGFWD 326
Query: 319 DIFSTSKPQYKKTPWCE----IFPYASSEAVDLME---RLIDWNPEARLTVEEALDHPFL 371
D + K P+ E +SS+ DL E + + W+P R T +E + PF
Sbjct: 327 DASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFF 386
Query: 372 Q 372
+
Sbjct: 387 E 387
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 115 bits (288), Expect = 1e-25
Identities = 99/367 (26%), Positives = 162/367 (43%), Gaps = 46/367 (12%)
Query: 73 YEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTS--------IFTREILLKRAIREL 124
Y +V+G GS+G VV+ V ++AIKKV + T ++L L
Sbjct: 164 YPTTEVVGHGSFGVVVTTVIIET---NQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGL 220
Query: 125 KFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLY 184
++ Y K + V L +++ P S YQ L + ++ + IK + Y
Sbjct: 221 QYYFYEKDEEDEVYLN--LVLDYMPQS---LYQRLRHF-----VNLKMQMPRVEIKFYAY 270
Query: 185 QILCGMKYIHSAD-VIHRDLKPGNILCS-ITGEIKICDFGLARGISPSFTVAGGISNHIT 242
Q+ + Y+H+ + HRD+KP N+L T KICDFG A+ + P
Sbjct: 271 QLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPD--------QPNV 322
Query: 243 NYVATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILG 302
+Y+ +R+YRAPEL+ YS VD+W+ C++AE KP+F G + Q++EI KI+G
Sbjct: 323 SYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMG 382
Query: 303 TPKQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTV 362
P + I + +F P K EIF + +DL+ + + ++P RL
Sbjct: 383 IPTKDEISGMNPNYEDHVF----PNIKPITLAEIFKAEDPDTLDLLTKTLKYHPCERLVP 438
Query: 363 EEALDHPFLQQVRNPEAEPICPHGP---FDFTYEKHLYSMERLRECLCDEVSKFHNDRQT 419
+ L + + + + + FDF E L + + +E +
Sbjct: 439 LQCLLSSYFDETKRCDTDTYVKAQNLRIFDFDVETELGHVPLVERPAIEE--------RL 490
Query: 420 KDFVSPP 426
K FVS P
Sbjct: 491 KHFVSAP 497
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 115 bits (288), Expect = 1e-25
Identities = 97/332 (29%), Positives = 154/332 (46%), Gaps = 33/332 (9%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLK-RAIRELKFMSYF 130
+YE ++ +G+G++G V + + AIKK+ RE AIRE+K
Sbjct: 3 KYENIKQVGEGAFGQVYKS---RRTSDGAVFAIKKMP--VDRETGFPFTAIREIKLCKSV 57
Query: 131 KGHRNIVSLIDLEIVNEEPYSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGM 190
+++I+ L EIV EE + ++ E + YDL ++ S S I+ Q++ +
Sbjct: 58 I-NKHIIGLD--EIVFEEGF--IFVVLEYMPYDLTGLLASGAKLSTDQIRSITSQLIEAV 112
Query: 191 KYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRWY 250
+H ++HRD+KP NIL G +K+ DFGL R IS +TN V T WY
Sbjct: 113 SSMHGMGLVHRDIKPSNILLDCHGMLKLTDFGLTREIS----------GMMTNRVCTLWY 162
Query: 251 RAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVIR 310
RAPEL+L YS VD W+VGCI+ E +P + G+D + Q+ I + LG P+
Sbjct: 163 RAPELLLGETSYSLKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQD---- 218
Query: 311 TYGSSRCYDIFSTSKPQYKKTPWCEIFPYA-SSEAVDLMERLIDWNPEARLTVEEALDHP 369
Y S D+ SK + + E + + E + ++ + RL+V +
Sbjct: 219 KYKWSDLLDVDIYSKSRSTEEIIAERYGHLFDEEELKVLSGFLCLTSRKRLSVANSRYFT 278
Query: 370 FLQQVRNPEAEPICPHGPFDFTYEKHLYSMER 401
+ +N + P F LY+ ER
Sbjct: 279 VISSHKN-------TYIPLSFEEAHELYTKER 303
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 115 bits (287), Expect = 2e-25
Identities = 92/308 (29%), Positives = 160/308 (51%), Gaps = 33/308 (10%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+Y+I Q +G+G Y S V +G E ++ IK + + R+ + R + L+ +S
Sbjct: 36 KYQIYQRMGRGKY----SEVFEGRKDRE-KIVIKALKPV--RKAKICREVLILRNLS--- 85
Query: 132 GHRNIVSLIDLEIVNEEP-YSGLYCYQELVDYDLARVIHSNVLFSEFHIKHFLYQILCGM 190
H+NI+ L+D+ + E YS ++ Y E DY I + + + I + QIL +
Sbjct: 86 -HKNIIKLMDVVVDPESQIYSLIFEYIEHEDY---AKIFEKLCYKD--IVEYSRQILSAL 139
Query: 191 KYIHSADVIHRDLKPGNILCS-ITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
Y HS +IHRD+KP N++ + E+KI D+GLA P + VA+R+
Sbjct: 140 SYCHSMGIIHRDIKPQNMVINQARRELKIIDWGLAEFYHPK--------KEYSVRVASRY 191
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEF-YGRKPVFMGNDSLHQVMEIQKILG-TPKQI 307
Y+ PEL++ + Y S+D+W+ GC+LAE + ++P F G + Q+++I +ILG T +
Sbjct: 192 YKGPELLVDYPYYDYSLDIWSFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKK 251
Query: 308 VIRTYGSSRC---YDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEE 364
+R Y + Y+ TP + Y + A+DL+E+++ ++ + R T +E
Sbjct: 252 YVRKYKMAPLNPKYEGVGERVLLSSFTPPGKTGLY--TNAIDLLEKILIYDHQDRPTADE 309
Query: 365 ALDHPFLQ 372
L HP +
Sbjct: 310 CLRHPLFE 317
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 114 bits (285), Expect = 3e-25
Identities = 89/301 (29%), Positives = 148/301 (48%), Gaps = 39/301 (12%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQLAIKKVTSIFTREILLKRAIRELKFMSYFK 131
+Y IL +G+G++G V A K T E+ +A+KKV + +A+RE+K + +
Sbjct: 3 QYCILGRIGEGAHGIVFKA--KHVETGEI-IALKKVALRRLEDGFPNQALREIKALQEME 59
Query: 132 GHRNIVSLIDLEIVNEEPYSGLYCYQ-ELVDYDLARVI-HSNVLFSEFHIKHFLYQILCG 189
++ +V L + P+ G + E + DLA V+ H+ ++ +K +L +L G
Sbjct: 60 DNQYVVQLKAVF-----PHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKG 114
Query: 190 MKYIHSADVIHRDLKPGNILCSITGEIKICDFGLARGISPSFTVAGGISNHITNYVATRW 249
+ + H+ +++HRDLKP N+L S +G++KI DFGLAR SP S T+ VATR
Sbjct: 115 VAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDG------SRLYTHQVATR- 167
Query: 250 YRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTPKQIVI 309
+VGCI+ E P+F G + + Q+ + +ILGTP V
Sbjct: 168 --------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVW 207
Query: 310 RTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHP 369
+ D S + P E+ P S +A+DL+ + + + P R+ +AL H
Sbjct: 208 PEL--TELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQ 265
Query: 370 F 370
+
Sbjct: 266 Y 266
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 114 bits (284), Expect = 4e-25
Identities = 94/342 (27%), Positives = 154/342 (44%), Gaps = 65/342 (19%)
Query: 72 RYEILQVLGKGSYGTVVSAVDKGNPTHEVQ--LAIKKVTSIFTREILLKRAIRELKFMSY 129
RYE+L+++GKGS+G V D H+++ +A+K V + + ++A E++ + +
Sbjct: 173 RYEVLKIIGKGSFGQVARVYD-----HKLRQYVALKMVRN---EKRFHRQAAEEIRILEH 224
Query: 130 FKGHRNIVSLIDLEIVNEEPYSGLYCYQ-ELVDYDLARVIHSNVL--FSEFHIKHFLYQI 186
K S+ + ++ + C EL+ DL +I N FS ++ F I
Sbjct: 225 LKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSI 284
Query: 187 LCGMKYIHSADVIHRDLKPGNILCSITGE--IKICDFGLARGISPSFTVAGGISNHITNY 244
L + +H +IH DLKP NIL G K+ DFG S F + Y
Sbjct: 285 LQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFG-----SSCFEY-----QKLYTY 334
Query: 245 VATRWYRAPELILSHKRYSKSVDMWAVGCILAEFYGRKPVFMGNDSLHQVMEIQKILGTP 304
+ +R+YRAPE+IL RYS +D+W+ CILAE +P+F G D Q+ + ++LG P
Sbjct: 335 IQSRFYRAPEIILG-SRYSTPIDIWSFRCILAELLTGQPLFPGEDEGDQLACMMELLGMP 393
Query: 305 KQIVIRTYGSSRCYDIFSTSKPQYKKTPWCEIFPYASSEAV------------------- 345
++ ++ Y I S P+Y C + A V
Sbjct: 394 PPKLLEQSKRAK-YFINSKGIPRY-----CSVTTQADGRVVLVGGRSRRGKKRGPPGSKD 447
Query: 346 --------------DLMERLIDWNPEARLTVEEALDHPFLQQ 373
+ ++R + W+P ARLT +AL HP++ +
Sbjct: 448 WGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISK 489
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 113 bits (283), Expect = 5e-25
Identities = 91/343 (26%), Positives = 161/343 (46%), Gaps = 39/343 (11%)
Query: 46 QNNHIYVDPILTKRSIYSPANFSVPGRYEILQVLGKGSYGTVVSAVDKGNPTHEV-QLAI 104
++ H ++D I++ ++ + G+ +G GS+GTV ++ N + AI
Sbjct: 19 EDEHYFIDDIVSIKNRQKSKMYVREGKR-----IGHGSFGTVTQSILSSNSIEWLGPYAI 73
Query: 105 KKVTSIFTREILLKRAIRELKFMSYFKGHRNIVSLIDLEIVNEEPYSGLYCYQ-----EL 159
K+V + L ++ ++ H N+V+L + G + YQ E
Sbjct: 74 KRVVKSPKVQSLELEILQNIR-------HPNLVTLEFFFESHCTTKDGGHLYQKNFVMEY 126
Query: 160 VDYDLARVIH----SNVLFSEFHIKHFLYQILCGMKYIHSADVIHRDLKPGNILC-SITG 214
+ L+ IH + HIK + +QIL + +HS + H DLKP NIL +G
Sbjct: 127 IPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSG 186
Query: 215 EIKICDFGLARGISPSFTVAGGISNHITNYVATRWYRAPELILSHKRYSKSVDMWAVGCI 274
K+CDFG A+ + + + Y +R+YRAPEL+L+ K Y+ +D+W++GCI
Sbjct: 187 IAKVCDFGSAQRLDDN--------TELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCI 238
Query: 275 LAEFYGRKPVFMGNDSLHQVMEIQKILGT-PKQIVIRTYGSSRCYDIFSTSKPQYKKTPW 333
+ E +P+F G+ + Q+ EI K+LG PK + S D S + ++KK +
Sbjct: 239 IGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSI---KNSQELQD--SLNDQKFKK--F 291
Query: 334 CEIFPYASSEAVDLMERLIDWNPEARLTVEEALDHPFLQQVRN 376
FP V+ + +++ ++ R + + H F +RN
Sbjct: 292 MHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRN 334
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.138 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,832,359
Number of Sequences: 60738
Number of extensions: 1227698
Number of successful extensions: 7760
Number of sequences better than 1.0e-05: 1422
Number of HSP's better than 0.0 without gapping: 390
Number of HSP's successfully gapped in prelim test: 1032
Number of HSP's that attempted gapping in prelim test: 4636
Number of HSP's gapped (non-prelim): 1910
length of query: 439
length of database: 30,389,216
effective HSP length: 109
effective length of query: 330
effective length of database: 23,768,774
effective search space: 7843695420
effective search space used: 7843695420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)