ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3065 good L KOG1636 Replication, recombination and repair DNA polymerase delta processivity factor (proliferating cell nuclear antigen)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3065 1056994 1057767 258
(258 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR088c [L] KOG1636 DNA polymerase delta processivity factor (pr... 382 e-106
SPBC16D10.09 [L] KOG1636 DNA polymerase delta processivity facto... 239 2e-63
At1g07370 [L] KOG1636 DNA polymerase delta processivity factor (... 230 1e-60
At2g29570 [L] KOG1636 DNA polymerase delta processivity factor (... 228 8e-60
CE14512 [L] KOG1636 DNA polymerase delta processivity factor (pr... 210 2e-54
Hs4505641 [L] KOG1636 DNA polymerase delta processivity factor (... 209 3e-54
7302405 [L] KOG1636 DNA polymerase delta processivity factor (pr... 209 3e-54
7298618 [L] KOG1636 DNA polymerase delta processivity factor (pr... 194 8e-50
ECU05g1030 [L] KOG1636 DNA polymerase delta processivity factor ... 84 2e-16
>YBR088c [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 258
Score = 382 bits (981), Expect = e-106
Identities = 182/258 (70%), Positives = 229/258 (88%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
MLEAKF EA LFKRIID F+DCVQL+NF C E GI AQAVDDSRVLLVSL I VEAF+E+
Sbjct: 1 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEY 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLME 120
R D V LG DLT+LSKILRCGNN+D LTLIA+++PDSI++LFEDTK+DR++EYSLKLM+
Sbjct: 61 RCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMD 120
Query: 121 IETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSI 180
I+ DFL+I +++Y+S +++PS++F+K VRDLSQLSDSINI++TK+TIKF A+GDIGSGS+
Sbjct: 121 IDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSV 180
Query: 181 VVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFD 240
++KPF D++HPE+SIK+ +++PVDL FGAKYL DIIKGSSLSD + I+LS EAPALFQFD
Sbjct: 181 IIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD 240
Query: 241 ISSGNLQFYLAPKFDEEE 258
+ SG LQF+LAPKF++EE
Sbjct: 241 LKSGFLQFFLAPKFNDEE 258
>SPBC16D10.09 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 260
Score = 239 bits (611), Expect = 2e-63
Identities = 113/258 (43%), Positives = 177/258 (67%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
MLEA+F +A L K+++D+ ++ V NF+C++ GI+ QA+D S V LVS+ I + FE +
Sbjct: 1 MLEARFQQAALLKKLLDAIKELVTDANFDCNDNGISLQAMDSSHVALVSMLIKSDGFEPY 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLME 120
R DRN+ LG +L LSK+LRC N D +TL AED+P+ + ++FE K DR+S+Y +KLM+
Sbjct: 61 RCDRNIALGINLNALSKVLRCAQNEDLVTLKAEDTPEVLNLVFESEKNDRISDYDVKLMD 120
Query: 121 IETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSI 180
I+ + L I D++Y++ ITMP+A+F + RDL LSDS+ I +K+ ++F+ +GDIG+GS
Sbjct: 121 IDQEHLGIPDIEYDATITMPAAEFQRITRDLLTLSDSVTINASKEGVRFSCKGDIGNGST 180
Query: 181 VVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFD 240
+K TDL + SI++++ + V L F KYL K + L+ +T+ +S + P L ++
Sbjct: 181 TLKQHTDLSDQDQSIEISLTQAVTLTFSLKYLAQFTKATPLATRVTLSMSNDVPLLVEYK 240
Query: 241 ISSGNLQFYLAPKFDEEE 258
+ SG L+FYLAPK EE+
Sbjct: 241 MESGFLRFYLAPKIGEED 258
>At1g07370 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 263
Score = 230 bits (587), Expect = 1e-60
Identities = 105/259 (40%), Positives = 175/259 (67%), Gaps = 1/259 (0%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
MLE + + L K++++S +D V NF+CS G + QA+D S V LVSL + E FE +
Sbjct: 1 MLELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHY 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLME 120
R DRN+ +G +L N+SK+L+C N D +T+ A+D D++ +FE +D+++++ +KLM+
Sbjct: 61 RCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMD 120
Query: 121 IETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSI 180
I+++ L I D +Y S + MPS +F++ +DLS + D++ I VTK+ +KF+ GDIG+ +I
Sbjct: 121 IDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANI 180
Query: 181 VVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFD 240
V++ T +D PE +I + +++PV L F +Y+N K + LSDT+TI LS E P + ++
Sbjct: 181 VLRQNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYK 240
Query: 241 ISS-GNLQFYLAPKFDEEE 258
++ G +++YLAPK +EEE
Sbjct: 241 VAEMGYIRYYLAPKIEEEE 259
>At2g29570 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 264
Score = 228 bits (580), Expect = 8e-60
Identities = 103/259 (39%), Positives = 174/259 (66%), Gaps = 1/259 (0%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
MLE + + L K+++++ +D V NF+CS G + QA+D S V LVSL + E FE +
Sbjct: 1 MLELRLVQGSLLKKVLEAVKDLVNDANFDCSTTGFSLQAMDSSHVALVSLLLRSEGFEHY 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLME 120
R DRN+ +G +L N+SK+L+C N D +T+ A+D D++ +FE +D+++++ +KLM+
Sbjct: 61 RCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGSDTVTFMFESPTQDKIADFEMKLMD 120
Query: 121 IETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSI 180
I+++ L I D +Y S + MPS +F++ +DLS + D++ I VTK+ +KF+ GDIG+ +I
Sbjct: 121 IDSEHLGIPDAEYHSIVRMPSGEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANI 180
Query: 181 VVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFD 240
V++ T +D PE +I + + +PV L F +Y+N K + LS+T+TI LS E P + ++
Sbjct: 181 VLRQNTTVDKPEDAIVIEMNEPVSLSFALRYMNSFTKATPLSETVTISLSSELPVVVEYK 240
Query: 241 ISS-GNLQFYLAPKFDEEE 258
++ G +++YLAPK +EEE
Sbjct: 241 VAEMGYIRYYLAPKIEEEE 259
>CE14512 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 263
Score = 210 bits (534), Expect = 2e-54
Identities = 105/260 (40%), Positives = 159/260 (60%), Gaps = 2/260 (0%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
M EAK AGL K+I++S +D V F+CSE ++ QA+D S V LVSL + V F+ +
Sbjct: 1 MFEAKLANAGLLKKIVESIKDLVTDAPFDCSETAMSLQAMDSSHVALVSLKLEVGLFDTY 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSP-DSILILFEDTKRDRVSEYSLKLM 119
R DR + LG L N+SK L+C NN D L E++ DSI+ F D KRD+ + ++K+M
Sbjct: 61 RCDRTINLGLSLANMSKALKCANNDDTCMLKYEENEGDSIIFTFADPKRDKTQDVTVKMM 120
Query: 120 EIETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGS 179
+I+++ L I D Y MP+ +F KT +DLS SDS+NI TK I F +GDIGS
Sbjct: 121 DIDSEHLGIPDQDYAVVCEMPAGEFQKTCKDLSTFSDSLNITATKAGIVFTGKGDIGSSV 180
Query: 180 IVVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQF 239
+ P ++ D ++ + ++ PV++ F KY+N K ++LSD + + L + P + ++
Sbjct: 181 VTYSPSSNTDDETEAVTLEVKDPVNVNFSIKYMNQFTKATALSDRVRLSLCNDVPVVVEY 240
Query: 240 DI-SSGNLQFYLAPKFDEEE 258
I +G L+FYLAPK D++E
Sbjct: 241 PIEENGYLRFYLAPKIDDDE 260
>Hs4505641 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 261
Score = 209 bits (532), Expect = 3e-54
Identities = 93/259 (35%), Positives = 171/259 (65%), Gaps = 1/259 (0%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
M EA+ + + K+++++ +D + ++ S G+ Q++D S V LV L++ E F+ +
Sbjct: 1 MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTY 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLME 120
R DRN+ +G +LT++SKIL+C N D +TL AED+ D++ ++FE +++VS+Y +KLM+
Sbjct: 61 RCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD 120
Query: 121 IETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSI 180
++ + L I + +Y + MPS +FA+ RDLS + D++ I KD +KF+A G++G+G+I
Sbjct: 121 LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNI 180
Query: 181 VVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFD 240
+ +++D E ++ + + +PV L F +YLN K + LS T+T+ +S + P + ++
Sbjct: 181 KLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK 240
Query: 241 ISS-GNLQFYLAPKFDEEE 258
I+ G+L++YLAPK ++EE
Sbjct: 241 IADMGHLKYYLAPKIEDEE 259
>7302405 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 260
Score = 209 bits (532), Expect = 3e-54
Identities = 94/259 (36%), Positives = 171/259 (65%), Gaps = 1/259 (0%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
M EA+ +A + K+I+D+ +D + F+CS+ GI QA+D+S V LVSL++ + F++F
Sbjct: 1 MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKF 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLME 120
R DRN+ +G +L +++KIL+C NN DN+T+ A+D+ D++ I+FE +++VS+Y +KLM
Sbjct: 61 RCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMN 120
Query: 121 IETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSI 180
++ + L I + + + MP+ +FA+ RDL+Q S+S+ I TK+ +KF+A GD+G+ +I
Sbjct: 121 LDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANI 180
Query: 181 VVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFD 240
+ +D E ++ + +++PV L F +YLN K + LS + + + + P + ++
Sbjct: 181 KLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYA 240
Query: 241 ISS-GNLQFYLAPKFDEEE 258
I G++++YLAPK ++ E
Sbjct: 241 IKDLGHIRYYLAPKIEDNE 259
>7298618 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 255
Score = 194 bits (494), Expect = 8e-50
Identities = 93/259 (35%), Positives = 163/259 (62%), Gaps = 6/259 (2%)
Query: 1 MLEAKFTEAGLFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEF 60
MLEA+ ++ L K+I+D+ ++ + +CSE G+ Q++D+S V LV+LS+ + FE+F
Sbjct: 1 MLEARLSQTLLLKKIVDALKEIIAQGTLDCSENGLELQSMDNSHVSLVALSLASDCFEKF 60
Query: 61 RADRNVVLGCDLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLME 120
DRNV LG DL +L K+L+C N+ D +T+ A D P+ I + FE ++R ++Y LKL+
Sbjct: 61 HCDRNVSLGLDLKSLGKVLKCANSDDAVTIKAVDRPEKITLSFESDGKERTADYELKLLN 120
Query: 121 IETDFLEISDMKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSI 180
++ D +EI Y +I +PS++FA+ RD+S +S+ I + I+F A+GD+G+ +I
Sbjct: 121 LDQDHMEIPKKDYTCFIQLPSSEFARICRDMSMFDESLTIACSSKGIRFLAKGDLGTANI 180
Query: 181 VVKPFTDLDHPESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFD 240
+ T +D + + +++PV F +YLN K + L+D + + LS+E P L ++
Sbjct: 181 QLSAGTAMD-----VSIEVQEPVTQSFAGRYLNTFTKATPLADRVKLYLSDERPLLVEYP 235
Query: 241 ISS-GNLQFYLAPKFDEEE 258
I G++++YLAPK ++ +
Sbjct: 236 IEDYGHIRYYLAPKVNDPD 254
>ECU05g1030 [L] KOG1636 DNA polymerase delta processivity factor (proliferating
cell nuclear antigen)
Length = 267
Score = 84.0 bits (206), Expect = 2e-16
Identities = 56/248 (22%), Positives = 112/248 (44%), Gaps = 5/248 (2%)
Query: 11 LFKRIIDSFRDCVQLINFNCSEKGIAAQAVDDSRVLLVSLSINVEAFEEFRADRNVVLGC 70
L KRI++S + V+ + +EKG++ Q +D + V + ++ F ++R DR +V+G
Sbjct: 23 LMKRILESLSEIVETADIKATEKGLSIQVMDVTHVAFADIFLSSTMFTKYRCDRELVIGV 82
Query: 71 DLTNLSKILRCGNNSDNLTLIAEDSPDSILILFEDTKRDRVSEYSLKLMEIETDFLEISD 130
L L KI++ + T E + + +T+ V + LKL +++ I +
Sbjct: 83 QLKTLIKIIKGMSVEGGGTFRMECDDATTNLNIRNTREGNVLSFKLKLFTSDSEAYNIPE 142
Query: 131 MKYESYITMPSADFAKTVRDLSQLSDSINILVTKDTIKFAAEGDIGSGSIVVKPFTDLDH 190
+++ T+P+ +F + + D + + T+ F G+ S+ F +
Sbjct: 143 FDFDASATIPADEFMYVPKLVGTFGDVVGVQAEGKTLMFFQTGEHADASM---SFEECPA 199
Query: 191 PESSIKVTIEKPVDLRFGAKYLNDIIKGSSLSDTITIKLSEEAPALFQFDISS-GNLQFY 249
E +K+ + KY+N I K L + I L + P F + +++ Y
Sbjct: 200 RE-ELKIEANTLITQEIAMKYVNLIGKVVPLCKEVKIFLGTKKPVFFNLCMDGVSHMKLY 258
Query: 250 LAPKFDEE 257
+APKF+ +
Sbjct: 259 VAPKFEND 266
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,829,956
Number of Sequences: 60738
Number of extensions: 540524
Number of successful extensions: 1442
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1424
Number of HSP's gapped (non-prelim): 9
length of query: 258
length of database: 30,389,216
effective HSP length: 104
effective length of query: 154
effective length of database: 24,072,464
effective search space: 3707159456
effective search space used: 3707159456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)