ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3068 good R KOG3139 General function prediction only N-acetyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3068 1058393 1057860 -178
(178 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR051w [R] KOG3139 N-acetyltransferase 247 5e-66
Hs18596951 [R] KOG3139 N-acetyltransferase 154 8e-38
SPBC15D4.06 [R] KOG3139 N-acetyltransferase 149 3e-36
At2g38130 [R] KOG3139 N-acetyltransferase 145 3e-35
CE07700 [R] KOG3139 N-acetyltransferase 144 5e-35
7290142 [R] KOG3139 N-acetyltransferase 142 3e-34
7290141 [R] KOG3139 N-acetyltransferase 142 3e-34
7292084_2 [R] KOG3139 N-acetyltransferase 127 6e-30
At1g03150 [R] KOG3234 Acetyltransferase (GNAT) family 65 6e-11
Hs10835057 [R] KOG3235 Subunit of the major N alpha-acetyltransf... 61 7e-10
CE18023 [R] KOG3235 Subunit of the major N alpha-acetyltransferase 60 1e-09
Hs14249280 [R] KOG3235 Subunit of the major N alpha-acetyltransf... 59 5e-09
7294847 [R] KOG3235 Subunit of the major N alpha-acetyltransferase 55 4e-08
7293615 [R] KOG3234 Acetyltransferase (GNAT) family 54 9e-08
At5g13780 [R] KOG3235 Subunit of the major N alpha-acetyltransfe... 53 2e-07
SPAC15E1.08 [R] KOG3235 Subunit of the major N alpha-acetyltrans... 52 6e-07
At5g11340 [R] KOG3138 Predicted N-acetyltransferase 49 4e-06
>YPR051w [R] KOG3139 N-acetyltransferase
Length = 176
Score = 247 bits (631), Expect = 5e-66
Identities = 123/169 (72%), Positives = 137/169 (80%), Gaps = 3/169 (1%)
Query: 2 VEIRYTRFDISNDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKP-- 59
+EI Y DI N+ +F++IKKLID DLSEPYSIYVYR+FLNQWP LTY+A SG P
Sbjct: 1 MEIVYKPLDIRNEEQFASIKKLIDADLSEPYSIYVYRYFLNQWPELTYIAVDNKSGTPNI 60
Query: 60 -IGCIVCKSDTHNGVRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETE 118
IGCIVCK D H VRLRGYIGMLAVE YRG GIAKKL+ +AID M E CDEIMLETE
Sbjct: 61 PIGCIVCKMDPHRNVRLRGYIGMLAVESTYRGHGIAKKLVEIAIDKMQREHCDEIMLETE 120
Query: 119 CSNAAALHLYENMGFIRMKRLFRYYLNQGDAFKLILPITEKSCVRSTFL 167
N+AAL+LYE MGFIRMKR+FRYYLN+GDAFKLILP+TEKSC RSTFL
Sbjct: 121 VENSAALNLYEGMGFIRMKRMFRYYLNEGDAFKLILPLTEKSCTRSTFL 169
>Hs18596951 [R] KOG3139 N-acetyltransferase
Length = 362
Score = 154 bits (388), Expect = 8e-38
Identities = 77/151 (50%), Positives = 104/151 (67%), Gaps = 4/151 (2%)
Query: 4 IRYTRFDISNDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCI 63
IRY R++ ++++ I +LI +DLSEPYSIY YR+F++ WP L +LA + +G I
Sbjct: 213 IRYVRYE--SELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMV--GEECVGAI 268
Query: 64 VCKSDTHNGVRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNAA 123
VCK D H + RGYI MLAV+ +YR GI L+ AI M++ CDE++LETE +N +
Sbjct: 269 VCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKS 328
Query: 124 ALHLYENMGFIRMKRLFRYYLNQGDAFKLIL 154
AL LYEN+GF+R KRLFRYYLN DA +L L
Sbjct: 329 ALKLYENLGFVRDKRLFRYYLNGVDALRLKL 359
>SPBC15D4.06 [R] KOG3139 N-acetyltransferase
Length = 150
Score = 149 bits (375), Expect = 3e-36
Identities = 72/135 (53%), Positives = 95/135 (70%), Gaps = 2/135 (1%)
Query: 20 IKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNGVRLRGYI 79
I +LI +DLSEPYS YVYR+F++QWP +++A + + IG ++CK D H G LRGYI
Sbjct: 15 ICQLIQKDLSEPYSKYVYRYFVHQWPEFSFVAL--DNDRFIGAVICKQDVHRGTTLRGYI 72
Query: 80 GMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNAAALHLYENMGFIRMKRL 139
MLA+ K+YRG+GIA KL ++D M + EI+LETE N AA+ YE +GF R KRL
Sbjct: 73 AMLAIVKEYRGQGIATKLTQASLDVMKNRGAQEIVLETEVDNEAAMSFYERLGFCRYKRL 132
Query: 140 FRYYLNQGDAFKLIL 154
+RYYLN DAF+ IL
Sbjct: 133 YRYYLNGTDAFRYIL 147
>At2g38130 [R] KOG3139 N-acetyltransferase
Length = 190
Score = 145 bits (366), Expect = 3e-35
Identities = 77/152 (50%), Positives = 99/152 (64%), Gaps = 5/152 (3%)
Query: 3 EIRYTRFDISNDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGC 62
EI YT + + + I L+D++LSEPYSI+ YR+F+ WP L +LA+ +G K +G
Sbjct: 15 EIEYTSY--AGEHHLPLIMSLVDQELSEPYSIFTYRYFVYLWPQLCFLAFHKG--KCVGT 70
Query: 63 IVCKSDTHNGVRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNA 122
IVCK H RGYI ML V K YRGRGIA +L+T AI M++ C+E+ LE E SN
Sbjct: 71 IVCKMGDHRQT-FRGYIAMLVVIKPYRGRGIASELVTRAIKAMMESGCEEVTLEAEVSNK 129
Query: 123 AALHLYENMGFIRMKRLFRYYLNQGDAFKLIL 154
AL LY +GFIR KRL+ YYLN DAF+L L
Sbjct: 130 GALALYGRLGFIRAKRLYHYYLNGMDAFRLKL 161
>CE07700 [R] KOG3139 N-acetyltransferase
Length = 278
Score = 144 bits (364), Expect = 5e-35
Identities = 70/147 (47%), Positives = 98/147 (66%)
Query: 13 NDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNG 72
++ + + I +LI +DLSEPYSIY YR+FL+ WP +LA+ + + IG ++CK +
Sbjct: 102 DESQINDIMRLITKDLSEPYSIYTYRYFLHNWPEYCFLAYDQTNNTYIGAVLCKLELDMY 161
Query: 73 VRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNAAALHLYENMG 132
R +GY+ MLAV++ R GI +L+ A+D M + CDEI+LETE SN A LY N+G
Sbjct: 162 GRCKGYLAMLAVDESCRRLGIGTRLVRRALDAMQSKGCDEIVLETEVSNKNAQRLYSNLG 221
Query: 133 FIRMKRLFRYYLNQGDAFKLILPITEK 159
FIR KRL +YYLN GDAF+L L T +
Sbjct: 222 FIRQKRLLKYYLNGGDAFRLKLIFTSR 248
>7290142 [R] KOG3139 N-acetyltransferase
Length = 383
Score = 142 bits (357), Expect = 3e-34
Identities = 77/144 (53%), Positives = 95/144 (65%), Gaps = 6/144 (4%)
Query: 11 ISNDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTH 70
ISN + I +LI +LSEPYSIY YR+F+ WP L +LA + +G IVCK D H
Sbjct: 243 ISNTQD---IMRLIQAELSEPYSIYTYRYFIYNWPKLCFLA--SHDNQYVGAIVCKLDMH 297
Query: 71 NGVRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNAAALHLYEN 130
VR RGYI MLAV K+YR I L+T AI+ M+ + DE++LETE N AL LYEN
Sbjct: 298 MNVR-RGYIAMLAVRKEYRKLKIGTTLVTKAIEAMLADNADEVVLETEMRNQPALRLYEN 356
Query: 131 MGFIRMKRLFRYYLNQGDAFKLIL 154
+GF+R KRLFRYYLN DA +L L
Sbjct: 357 LGFVRDKRLFRYYLNGVDALRLKL 380
>7290141 [R] KOG3139 N-acetyltransferase
Length = 402
Score = 142 bits (357), Expect = 3e-34
Identities = 77/144 (53%), Positives = 95/144 (65%), Gaps = 6/144 (4%)
Query: 11 ISNDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTH 70
ISN + I +LI +LSEPYSIY YR+F+ WP L +LA + +G IVCK D H
Sbjct: 262 ISNTQD---IMRLIQAELSEPYSIYTYRYFIYNWPKLCFLA--SHDNQYVGAIVCKLDMH 316
Query: 71 NGVRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNAAALHLYEN 130
VR RGYI MLAV K+YR I L+T AI+ M+ + DE++LETE N AL LYEN
Sbjct: 317 MNVR-RGYIAMLAVRKEYRKLKIGTTLVTKAIEAMLADNADEVVLETEMRNQPALRLYEN 375
Query: 131 MGFIRMKRLFRYYLNQGDAFKLIL 154
+GF+R KRLFRYYLN DA +L L
Sbjct: 376 LGFVRDKRLFRYYLNGVDALRLKL 399
>7292084_2 [R] KOG3139 N-acetyltransferase
Length = 171
Score = 127 bits (320), Expect = 6e-30
Identities = 67/142 (47%), Positives = 90/142 (63%), Gaps = 2/142 (1%)
Query: 13 NDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNG 72
++ + + LID++LSEPYSIY YR+F+ WP+L + A + +G IVCK +
Sbjct: 19 DESQLKVLMGLIDKELSEPYSIYTYRYFVYNWPDLCFFAL--DGDRYVGVIVCKLEAKRD 76
Query: 73 VRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNAAALHLYENMG 132
L+GYI MLAV+ +YR RGI + L +AID M I+LETE SN AL LY+++G
Sbjct: 77 GYLQGYIAMLAVDAEYRKRGIGRALSEMAIDAMAIRDAAMIVLETELSNKPALALYQSLG 136
Query: 133 FIRMKRLFRYYLNQGDAFKLIL 154
FIR +R RYYLN DAF L L
Sbjct: 137 FIRERRFLRYYLNGMDAFHLKL 158
>At1g03150 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 174
Score = 64.7 bits (156), Expect = 6e-11
Identities = 41/148 (27%), Positives = 75/148 (49%), Gaps = 10/148 (6%)
Query: 8 RFDISNDMEFSTIKKLIDEDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKS 67
RF ++ + F+++ + L+E +++ Y +L +WP+ Y AEG G + +
Sbjct: 6 RFSCNDLLRFTSVNL---DHLTETFNMSFYMTYLARWPD--YFHVAEGPGNRVMGYIMGK 60
Query: 68 DTHNGVRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDE---IMLETECSNAAA 124
G G++ + V +YR + +AKKL+ L D I +K D+ + L SN A
Sbjct: 61 VEGQGESWHGHVTAVTVSPEYRRQQLAKKLMNLLED--ISDKIDKAYFVDLFVRASNTPA 118
Query: 125 LHLYENMGFIRMKRLFRYYLNQGDAFKL 152
+ +YE +G+I +R+ RYY + D +
Sbjct: 119 IKMYEKLGYIIYRRVLRYYSGEEDGLDM 146
>Hs10835057 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 235
Score = 61.2 bits (147), Expect = 7e-10
Identities = 43/133 (32%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Query: 28 LSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNGVRLRGYIGMLAVEKQ 87
L E Y + Y + WP L+Y+A E +GK +G ++ K + G+I LAV++
Sbjct: 22 LPENYQMKYYFYHGLSWPQLSYIAEDE-NGKIVGYVLAKMEEDPDDVPHGHITSLAVKRS 80
Query: 88 YRGRGIAKKLITLAIDTMIDE-KCDEIMLETECSNAAALHLYEN-MGFIRMKRLFRYYLN 145
+R G+A+KL+ A MI+ + L SN AALHLY N + F + +YY +
Sbjct: 81 HRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYAD 140
Query: 146 QGDAFKLILPITE 158
DA+ + +T+
Sbjct: 141 GEDAYAMKRDLTQ 153
>CE18023 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 182
Score = 60.5 bits (145), Expect = 1e-09
Identities = 38/127 (29%), Positives = 64/127 (49%), Gaps = 3/127 (2%)
Query: 28 LSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNGVRLRGYIGMLAVEKQ 87
L E Y + Y + WP L+Y+A + G +G ++ K + G G+I LAV++
Sbjct: 22 LPENYQMKYYFYHALSWPQLSYIA-EDHKGNVVGYVLAKMEEDPGEEPHGHITSLAVKRS 80
Query: 88 YRGRGIAKKLITLAIDTMIDE-KCDEIMLETECSNAAALHLYEN-MGFIRMKRLFRYYLN 145
YR G+A K++ M++ + L SN AAL+LY+N + F + +YY +
Sbjct: 81 YRRLGLANKMMDQTARAMVETYNAKYVSLHVRVSNRAALNLYKNTLKFEIVDTEPKYYAD 140
Query: 146 QGDAFKL 152
DA+ +
Sbjct: 141 GEDAYAM 147
>Hs14249280 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 229
Score = 58.5 bits (140), Expect = 5e-09
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 28 LSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNGVRLRGYIGMLAVEKQ 87
L E Y + Y + WP L+Y+A E GK +G ++ K + G+I LAV++
Sbjct: 22 LPENYQMKYYLYHGLSWPQLSYIAEDE-DGKIVGYVLAKMEEEPDDVPHGHITSLAVKRS 80
Query: 88 YRGRGIAKKLITLAIDTMIDE-KCDEIMLETECSNAAALHLYEN-MGFIRMKRLFRYYLN 145
+R G+A+KL+ A MI+ + L SN ALHLY N + F + +YY +
Sbjct: 81 HRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRPALHLYSNTLNFQISEVEPKYYAD 140
Query: 146 QGDAFKL 152
DA+ +
Sbjct: 141 GEDAYAM 147
>7294847 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 196
Score = 55.5 bits (132), Expect = 4e-08
Identities = 41/135 (30%), Positives = 69/135 (50%), Gaps = 5/135 (3%)
Query: 28 LSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTH--NGVRLRGYIGMLAVE 85
L E Y + Y + WP L+Y+A + G +G ++ K + N G+I LAV+
Sbjct: 22 LPENYQMKYYFYHGLTWPQLSYVA-VDDKGAIVGYVLAKMEEPEPNEESRHGHITSLAVK 80
Query: 86 KQYRGRGIAKKLITLAIDTMID-EKCDEIMLETECSNAAALHLYEN-MGFIRMKRLFRYY 143
+ YR G+A+KL+ A M++ + L SN AAL+LY N + F ++ +YY
Sbjct: 81 RSYRRLGLAQKLMNQASQAMVECFNAQYVSLHVRKSNRAALNLYTNALKFKIIEVEPKYY 140
Query: 144 LNQGDAFKLILPITE 158
+ DA+ + ++E
Sbjct: 141 ADGEDAYAMRRDLSE 155
>7293615 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 175
Score = 54.3 bits (129), Expect = 9e-08
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Query: 26 EDLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNGVRLRGYIGMLAVE 85
+ L+E Y + Y +L +WP LA + SG+ +G I+ K + H G++ L V
Sbjct: 21 DPLTETYGLSFYTQYLAKWPEYFQLAESP-SGQIMGYIMGKVEGHLD-NWHGHVTALTVS 78
Query: 86 KQYRGRGIAKKLITLAIDTMIDEKCDEIMLETECSNAAALHLYENMGFIRMKRLFRYYLN 145
YR G+A L++ D ++ + L SN A+++Y N+G+I + + YY
Sbjct: 79 PDYRRLGLAALLMSFLEDISEKKRAYFVDLFVRKSNQVAINMYTNLGYIIYRTILEYYSG 138
Query: 146 QGD 148
D
Sbjct: 139 DQD 141
>At5g13780 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 192
Score = 53.1 bits (126), Expect = 2e-07
Identities = 38/127 (29%), Positives = 65/127 (50%), Gaps = 4/127 (3%)
Query: 28 LSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTHNGVRLRGYIGMLAVEKQ 87
L E Y + Y + + WP L Y+A + +G+ +G ++ K + + G+I LAV +
Sbjct: 23 LPENYQMKYYLYHILSWPQLLYVA-EDYNGRIVGYVLAKMEEESN-ECHGHITSLAVLRT 80
Query: 88 YRGRGIAKKLITLAIDTMID-EKCDEIMLETECSNAAALHLY-ENMGFIRMKRLFRYYLN 145
+R G+A KL+T A M + + + L SN AA +LY E +G+ +YY +
Sbjct: 81 HRKLGLATKLMTAAQAAMEQVYEAEYVSLHVRRSNRAAFNLYTETLGYKINDVEAKYYAD 140
Query: 146 QGDAFKL 152
DA+ +
Sbjct: 141 GEDAYDM 147
>SPAC15E1.08 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 177
Score = 51.6 bits (122), Expect = 6e-07
Identities = 37/130 (28%), Positives = 68/130 (51%), Gaps = 6/130 (4%)
Query: 27 DLSEPYSIYVYRFFLNQWPNLTYLAWAEGSGKPIGCIVCKSDTH--NGVRLRGYIGMLAV 84
+L E Y + Y + WP L+Y+A + G+ +G ++ K + +G+ G+I ++V
Sbjct: 21 NLPENYQLKYYLYHAISWPMLSYVA-TDPKGRVVGYVLAKMEEEPKDGIP-HGHITSVSV 78
Query: 85 EKQYRGRGIAKKLITLAIDTMIDEKCDEIM-LETECSNAAALHLY-ENMGFIRMKRLFRY 142
+ YR G+AK+L+ + M++ + M L SN AA+HLY + + F +Y
Sbjct: 79 MRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKY 138
Query: 143 YLNQGDAFKL 152
Y + DA+ +
Sbjct: 139 YADGEDAYAM 148
>At5g11340 [R] KOG3138 Predicted N-acetyltransferase
Length = 164
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/86 (30%), Positives = 39/86 (45%)
Query: 60 IGCIVCKSDTHNGVRLRGYIGMLAVEKQYRGRGIAKKLITLAIDTMIDEKCDEIMLETEC 119
+G I C+ + +R YI L V YRG GI L+ +D + EI L +
Sbjct: 59 VGAIACRLEKKESGAMRVYIMTLGVLAPYRGIGIGSNLLNHVLDMCSKQNMCEIYLHVQT 118
Query: 120 SNAAALHLYENMGFIRMKRLFRYYLN 145
+N A+ Y+ GF + YY+N
Sbjct: 119 NNEDAIKFYKKFGFEITDTIQNYYIN 144
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.141 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,517,886
Number of Sequences: 60738
Number of extensions: 435452
Number of successful extensions: 1296
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1264
Number of HSP's gapped (non-prelim): 17
length of query: 178
length of database: 30,389,216
effective HSP length: 99
effective length of query: 79
effective length of database: 24,376,154
effective search space: 1925716166
effective search space used: 1925716166
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)