ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3109 good U KOG1077 Intracellular trafficking, secretion, and vesicular transport Vesicle coat complex AP-2, alpha subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3109 1068225 1071080 952
(952 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBL037w [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 733 0.0
SPBC691.03c [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 228 3e-59
7296210 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 222 2e-57
At5g22770 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 215 3e-55
At5g22780 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 214 7e-55
CE28680 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 212 2e-54
Hs19913416 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 210 7e-54
Hs19913414 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit 210 7e-54
Hs18104998 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 118 5e-26
At1g23900 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 115 3e-25
At1g60070 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 111 5e-24
SPCP1E11.06 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 105 3e-22
Hs4503843 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 96 3e-19
7291008 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 91 7e-18
CE25176 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 89 4e-17
Hs6671551 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 68 8e-11
>YBL037w [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 1025
Score = 733 bits (1892), Expect = 0.0
Identities = 415/1014 (40%), Positives = 614/1014 (59%), Gaps = 73/1014 (7%)
Query: 6 NQQNNMKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFT---QKSG----LNGYQRKK 58
N + +KGLQLFIADLR+ Q+ +E +RIQ+E+ I+ F +K G L GYQRKK
Sbjct: 14 NNNSTIKGLQLFIADLRSAQQAQEQEKRIQSEIVKIKQHFDAAKKKQGNHDRLGGYQRKK 73
Query: 59 YVAKMAYIYITTNAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVL 118
YVAK+AYIYIT+N + E+LFGL+Q +LLKSS FSEK+IGYMTLELL+ + V V
Sbjct: 74 YVAKLAYIYITSNTTKLNEILFGLEQTVELLKSSIFSEKFIGYMTLELLYERSEVVAKVN 133
Query: 119 EKTISCLKLDLSSGDANAVSLALNFVGIVGNRDEIFA--DNLSETIFGILRSPVSSAILK 176
++ L DLSS D N V LALNFVG+VG A D+++ +F ILRSP SS LK
Sbjct: 134 DEVNYQLMKDLSSSDDNFVMLALNFVGVVGELTNRLAYNDDITTGVFKILRSPTSSIYLK 193
Query: 177 RKACLAFLTLIRYKPQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREI 236
+K+ L+FL L++ ILT + ++ LWI+RI +LL D ++ EFIA+ I
Sbjct: 194 KKSALSFLALLKSNHSILTE-DLQRKQLWIQRILSLLDDTENYRLTLATIPLIEFIAKYI 252
Query: 237 DVNPCLRLIPQLAEILHECL----SKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVS- 291
D + C RL+PQL EIL+ C+ S+ ++ +Y F+ + NPW++ VSLL +L++
Sbjct: 253 DPSYCTRLLPQLTEILYNCVVVGTSRSSDNQFPLEYTFANMPNPWLITKVVSLLSILIAS 312
Query: 292 ----DNGENLIGSNIDQQTLGKLRVCVSHAVSFALASDANPVTKNAQYSVMFTMLGFACK 347
D+G L +NID + L KLR CVS A+ +P+ + Q +V+F+++ FA K
Sbjct: 313 PTERDSGSLLQTNNIDNELLNKLRKCVSVAIELGTRQAQDPMERIVQNTVLFSLINFASK 372
Query: 348 LDPTNEAISNSVTGLCELMTSNDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDM 407
LDP++EAISNSVT LC L+TS ++N RY T D L+K+C +G AI ++ ++L + +
Sbjct: 373 LDPSDEAISNSVTALCSLLTSKEINIRYLTLDSLVKLCSSSGKPAIDAVRYKNLDMIFHL 432
Query: 408 LKRESDVTLLRKIIDLLVILTDVSNFKFVVQELLSALEAHKSM-DFALREDLSFQIERLI 466
L E D +++RK++DLL TDV N K +V LL + + K++ + ++ D++ +I L
Sbjct: 433 LNTERDSSIVRKVVDLLYTFTDVENVKIIVDGLLQYILSPKNLAEPQIKSDIAVKIAILT 492
Query: 467 ELHADDLNWFVXXXXX--XXXXNTSIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAP 524
E +A D+NWFV NT+I +D +W+R+CQIVVNN LH++ CE L+DYL
Sbjct: 493 EKYATDINWFVIISLQLLSLTSNTTINDDEIWQRLCQIVVNNPSLHRITCERLVDYLCKK 552
Query: 525 NVAESLVKAGVFLLAEYASLVNDKVSAGDLFNLFTEKYFQVSNLTKAMILTGMLKLYHVE 584
+E+++KA FLL EY+SL+ D++S+ +LF LF EKYF N+ KAMILT M+KLY
Sbjct: 553 QASEAIIKAAAFLLGEYSSLITDRISSANLFTLFAEKYFSAPNVAKAMILTTMIKLYKTS 612
Query: 585 PQLSSVVVKFFQLELNSFDVILQTRSYEYLKIIQYSKMNDMTFIDKLL-PGMPPFASSKD 643
P++ S V+KFFQLELNS D+ LQTRS+EYL IIQ +K+N T I ++L MPPF S +
Sbjct: 613 PEIGSNVIKFFQLELNSLDIELQTRSFEYLNIIQLAKVNGNTDILQILFEPMPPFNSKSN 672
Query: 644 TDI--MSKLPKTQELLSL--EQPFTSGNTVDSNNKPAS------LPTPPRSRKN------ 687
+ + LP + +L S +T D +K A+ +P PP SR+N
Sbjct: 673 PLLKRLGSLPASAGSTTLINTPSEASSSTPDLLSKRANSSRSIMVPMPPPSRRNTIDDVN 732
Query: 688 ------------NKLYHSQQLTPGWESGFKRMLIHTQGVFYQDTLVSVLFRVETKE-EQP 734
+ Y Q L P W GF RM+ H QGV + +L+ V +R+ T + +QP
Sbjct: 733 SKISSSEDFSGKDSYYSRQILAPNWREGFTRMISHKQGVLFTSSLMKVFYRITTPDAQQP 792
Query: 735 STSKITFTYVNKSDWEITGLSCEIIPLRADNNPPYVLQVLQSPDSKLAPSNGRTSYTFEI 794
I+ ++N ++WEITGLS +IIP + NP Y++ + +P + + R ++E+
Sbjct: 793 YVFHISLAFINLTEWEITGLSTQIIPSKTQGNPEYLIMNINTPSTATIGPHKRAEQSYEV 852
Query: 795 TTRFPFPQEHASLLSSQFKCGGQYCSHRLK--IGYT---ILSTLSPRISEIKLAQFVQRW 849
+ R PF E + +L+ FKCGG + LK IG T I S ++P + + LAQF+ RW
Sbjct: 853 SIRKPFDVEDSPILAIHFKCGGSTNTINLKTAIGMTTTLISSDVNPSM-HLNLAQFISRW 911
Query: 850 KSIGDSLGKAGEH-------------VDVVECQHTNLQKLMKTMSKVGFDVVQQSSIPNI 896
K++ D+LGK GE+ V+ + + L L +T+ ++GFD+V Q+S+ +
Sbjct: 912 KTLSDALGKEGEYQKSGIKLNKDFRKVETISLE-DGLLLLTQTVKRLGFDIVDQTSVRST 970
Query: 897 AFAGGILHTKSDGNYGCXXXXXXXXXXXXVQITCKTTSSGDLSRFVINCIKKVV 950
F GI+HTKS+GN+GC V +TCKTT++G L+++++ CIK V+
Sbjct: 971 LFVSGIIHTKSEGNFGC-LMKIQYQVNGTVNVTCKTTTAGPLAKYIVECIKNVL 1023
>SPBC691.03c [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 878
Score = 228 bits (581), Expect = 3e-59
Identities = 196/756 (25%), Positives = 349/756 (45%), Gaps = 70/756 (9%)
Query: 9 NNMKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYI 68
NNMKGL+ FI+DLR+ + E +R+ EL IR +F Q S L+ Y RKKYV+K+ YIY+
Sbjct: 5 NNMKGLRAFISDLRSLEHDDEE-KRVNVELAKIRAKF-QSSTLSAYDRKKYVSKLLYIYM 62
Query: 69 TTNAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLD 128
+ + FG + +LL + +SEK IGY+ + LL N + +++ I+ +K D
Sbjct: 63 -----LGYPITFGHMEAAKLLSGTKYSEKLIGYLAVALLLNE---NHELMKLVINSIKKD 114
Query: 129 LSSGDANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIR 188
L S D+ SLAL+ + +G R+ + + I+ +L S + I+++K+ LA L + R
Sbjct: 115 LLSHDSLQNSLALHTIANIGGRE--LCETVYYDIYKLLMSASNENIVRQKSALALLHIYR 172
Query: 189 YKPQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDVNPCL--RLIP 246
P ++ N E W E I +LGD++ + + RE + +
Sbjct: 173 KFPDLI-NPE------WFEPIVMILGDDDLNVSLAVSNFVNLIVIREPKYQKFAYGKAVG 225
Query: 247 QLAEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQT 306
+L I+ E +DY + V PW+ V+L ++L++ + D T
Sbjct: 226 KLKNIVFE-------HGYSSDYLYYSVPCPWLQ---VNLCRILLACERPS------DNPT 269
Query: 307 LGKLRVCVSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELM 366
L + +S ++N NA +++F + A +D ++ + L +++
Sbjct: 270 RATLIRVLDRILSLP-NDNSNVQQVNAVNAILFEAIKLAFLVDESHSLYEKCMDRLADMI 328
Query: 367 TSNDLNTRYSTFDLLIKICKV-NGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLV 425
+ N RY F+ + + T++K H L+ R DV+L +K ++LL
Sbjct: 329 ADKESNIRYLAFETTAYLISCGHSITSLK-----HYKELILSSLRYKDVSLRKKSLELLY 383
Query: 426 ILTDVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXX 485
++ D N K +V +LL L +D +EDL ++ + E A D W+V
Sbjct: 384 MMCDEENAKLIVADLLQYLP---HLDSVTQEDLISKVAIISETFATDYEWYVDVTIQLLR 440
Query: 486 XNTSIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYASLV 545
+D VW ++ ++VNNE + + A + L L + + E LVKAG ++L E+ L+
Sbjct: 441 IAGKSADDGVWHQLVHVIVNNEEIQEYATKRLFSLLQSETIHECLVKAGGYVLGEFGHLI 500
Query: 546 NDKVSAGDL--FNLFTEKYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQLELNSFD 603
D + + F+ K S T+ ++LT ++KL +++P+L+ + K FQ +
Sbjct: 501 TDYPDSQPVHQFSTIYRKLNVSSPSTRVLLLTTLIKLANLQPELNDRIAKVFQEYSTIIN 560
Query: 604 VILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPKTQELLSLEQPF 663
+Q R+ EYL++++ + F+ + +PPF + PK++ +
Sbjct: 561 PEVQQRACEYLQLLKMPR----DFLQLVCDEVPPFLDGNRDGVH---PKSRPSSKVNLVD 613
Query: 664 TSGNTVDSNNKPASLPTPPRSRKNNKLYHSQQLTPGWESGFKRMLIHTQGVFYQDTLVSV 723
T T+ + +KP++ P Y P GF R+ +G+ YQD+ + +
Sbjct: 614 TYPQTIPNVSKPSTPIDVPE-------YDISACLP----GFYRLCWKDKGILYQDSQIQI 662
Query: 724 LFRVETKEEQPSTSKITFTYVNKSDWEITGLSCEII 759
R E S I Y N+ + LS +I
Sbjct: 663 GVR---SEYHNSEGAIYLYYENRQSNTLKSLSSTLI 695
>7296210 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 932
Score = 222 bits (566), Expect = 2e-57
Identities = 220/948 (23%), Positives = 412/948 (43%), Gaps = 97/948 (10%)
Query: 11 MKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITT 70
M+GL +FI+D+R + + +RI EL NIR++F L+GYQ+KKYV K+ +I++
Sbjct: 1 MRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLG 60
Query: 71 NAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLS 130
+ ++ FG + LL S+ +SEK IGY+ + +L N + ++ I +K DL
Sbjct: 61 H-----DIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVN---TNSDLIRLIIQSIKNDLQ 112
Query: 131 SGDANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYK 190
S + V+LAL + +G+RD A++ S I +L S + ++K+ A L L L R
Sbjct: 113 SRNPVHVNLALQCIANIGSRD--MAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSS 170
Query: 191 PQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREID-VNPCLRL-IPQL 248
P I+ E W RI LL D++ + R D C+ L + +L
Sbjct: 171 PDIIPGGE------WTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRL 224
Query: 249 AEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLG 308
+ I+ + Q DY + V PW+ + LLQ E + + +++
Sbjct: 225 SRIVTASYTDLQ------DYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNE---- 274
Query: 309 KLRVCVSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTS 368
L ++ A + NA+ +V+F + D + + L + +++
Sbjct: 275 TLETILNKAQEPPKSKKVQ--HSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSN 332
Query: 369 NDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILT 428
+ N RY + +C + + +H ++ +K E DV++ + +DLL +
Sbjct: 333 RETNLRYLALE---SMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMC 389
Query: 429 DVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNT 488
D N + +VQE+L+ LE + D+++RE++ ++ L E +A D W+V
Sbjct: 390 DRGNAEEIVQEMLNYLE---TADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAG 446
Query: 489 SIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYASLVNDK 548
++ VW R+ QIV+N E + A + + + L AP E++VK G ++L E+ +L+
Sbjct: 447 DYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGD 506
Query: 549 VSAGDL--FNLFTEKYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQ--LELNSFDV 604
+ L F L KY S +T+A++L+ +K ++ P++ + + F+ L S D
Sbjct: 507 SRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADA 566
Query: 605 ILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPKTQELLSLEQ--- 661
LQ R+ EYL++ + + + + + +P P SS + K P + +
Sbjct: 567 ELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKS 626
Query: 662 --PFTSG--------------NTVDSNNKPASLPTPPR------SRKNNKLYHSQQLTPG 699
P TS N ++N L TPP S N+ L G
Sbjct: 627 PAPLTSAAQNNALVNNSHSKLNNSNANTDLLGLSTPPSNNIGSGSNSNSTLIDVLGDMYG 686
Query: 700 WES--------GFKRMLIHTQGVFYQDTLVSVLFRVETKEEQPSTSKITFTYVNKSDWEI 751
S K+ L GV +++ ++ + + E ++ + ++ Y NK+ +
Sbjct: 687 SNSNNNSSAVYNTKKFLFKNNGVLFENEMLQIGVKSEFRQ---NLGRLGLFYGNKTQVPL 743
Query: 752 TGLSCEIIPLRADNNPPYVLQVLQSPDSKLAPSNGRTSYTFEITTRFPFPQEHASLLSSQ 811
T + ++ A++ +Q+ + A + + T E + A +
Sbjct: 744 TNFN-PVLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLTAECIEDY----ADAPTIEIS 798
Query: 812 FKCGGQYCSHRLKIGYTILSTLSPRISEIKLAQFVQRWKSI------GDSLGKAGEHVDV 865
F+ G +K+ ++ P +E+ F RWK++ + KA + +D+
Sbjct: 799 FRYNGTQQKFSIKLPLSVNKFFEP--TEMNAESFFARWKNLSGEQQRSQKVFKAAQPLDL 856
Query: 866 VECQHTNLQKLMKTMSKVGFDVVQQSSIPNIAFAGGILHTKSDGNYGC 913
++ + M+ + +V P+ GI+HT+S GC
Sbjct: 857 PGARNKLMGFGMQLLDQV-------DPNPDNMVCAGIIHTQSQ-QVGC 896
>At5g22770 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 1012
Score = 215 bits (547), Expect = 3e-55
Identities = 188/688 (27%), Positives = 322/688 (46%), Gaps = 64/688 (9%)
Query: 11 MKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITT 70
M+GL +FI+D+R Q + R+ EL NIRT F + L Y++KKYV KM YI++
Sbjct: 4 MRGLSVFISDVRNCQNKEAERLRVDKELGNIRTCFKNEKVLTPYKKKKYVWKMLYIHM-- 61
Query: 71 NAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLS 130
+ ++ FG + L+ + + EK +GY+ L N + L+ I+ ++ D+
Sbjct: 62 ---LGYDVDFGHMEAVSLISAPKYPEKQVGYIVTSCLLNE---NHDFLKLAINTVRNDII 115
Query: 131 SGDANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYK 190
+ LAL VG +G RD FA++L+ + +L S ++++KA L L L R
Sbjct: 116 GRNETFQCLALTLVGNIGGRD--FAESLAPDVQKLLISSSCRPLVRKKAALCLLRLFRKN 173
Query: 191 PQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREID--VNPCLRLIPQL 248
P + N++ W +R+ LL DE D G + + CL P+
Sbjct: 174 PDAV-NVDG-----WADRMAQLL-DERDLGVLTSSTSLLVALVSNNHEAYSSCL---PKC 223
Query: 249 AEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLG 308
+IL E L++ Q+ + Y + G+ +PW+ + LQ + I+ +
Sbjct: 224 VKIL-ERLARNQDVPQE--YTYYGIPSPWLQVKAMRALQYFPT----------IEDPSTR 270
Query: 309 KLRVCVSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTS 368
K V + N NA ++V+F L LD E +S V L + ++
Sbjct: 271 KALFEVLQRILMGTDVVKNVNKNNASHAVLFEALSLVMHLDAEKEMMSQCVALLGKFISV 330
Query: 369 NDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILT 428
+ N RY + + ++ V T ++ I +H ++++ LK + D+++ R+ +DLL +
Sbjct: 331 REPNIRYLGLENMTRMLMV---TDVQDIIKKHQSQIITSLK-DPDISIRRRALDLLYGMC 386
Query: 429 DVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNT 488
DVSN K +V+ELL L + +F++RE+LS + L E A DL+W+V
Sbjct: 387 DVSNAKDIVEELLQYLS---TAEFSMREELSLKAAILAEKFAPDLSWYVDVILQLIDKAG 443
Query: 489 SIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYASLV--N 546
+D +W R+ Q V NNE L A +YL + E++VK ++L EY L+
Sbjct: 444 DFVSDDIWFRVVQFVTNNEDLQPYAASKAREYLDKIAIHETMVKVSAYILGEYGHLLARQ 503
Query: 547 DKVSAGDLFNLFTEKYFQVSNLTKAMILTGMLK-LYHV---EPQLSSVVVKFFQLELNSF 602
SA +LF++ EK +S T ++L+ K L H +P+L V F+ +
Sbjct: 504 PGCSASELFSILHEKLPTISTPTIPILLSTYAKLLMHAQPPDPELQKKVWAVFKKYESCI 563
Query: 603 DVILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPKTQE------- 655
DV +Q R+ EY ++ F+D +L MP F + + ++ K ++
Sbjct: 564 DVEIQQRAVEYFEL----SKKGPAFMD-VLAEMPKF-PERQSSLIKKAENVEDTADQSAI 617
Query: 656 -LLSLEQPFTSGNTVDSNNKPASLPTPP 682
L + +QP S V ++ +P + PP
Sbjct: 618 KLRAQQQP--SNAMVLADQQPVNGAPPP 643
>At5g22780 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 1013
Score = 214 bits (544), Expect = 7e-55
Identities = 188/688 (27%), Positives = 322/688 (46%), Gaps = 64/688 (9%)
Query: 11 MKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITT 70
M+GL +FI+D+R Q + R+ EL NIRT F + L Y++KKYV KM YI++
Sbjct: 4 MRGLSVFISDVRNCQNKEAERLRVDKELGNIRTCFKNEKVLTPYKKKKYVWKMLYIHM-- 61
Query: 71 NAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLS 130
+ ++ FG + L+ + + EK +GY+ L N + L+ I+ ++ D+
Sbjct: 62 ---LGYDVDFGHMEAVSLISAPKYPEKQVGYIVTSCLLNE---NHDFLKLAINTVRNDII 115
Query: 131 SGDANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYK 190
+ LAL VG +G RD FA++L+ + +L S ++++KA L L L R
Sbjct: 116 GRNETFQCLALTLVGNIGGRD--FAESLAPDVQKLLISSSCRPLVRKKAALCLLRLFRKN 173
Query: 191 PQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREID--VNPCLRLIPQL 248
P + N++ W +R+ LL DE D G + + CL P+
Sbjct: 174 PDAV-NVDG-----WADRMAQLL-DERDLGVLTSSTSLLVALVSNNHEAYSSCL---PKC 223
Query: 249 AEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLG 308
+IL E L++ Q+ + Y + G+ +PW+ + LQ + I+ +
Sbjct: 224 VKIL-ERLARNQDVPQE--YTYYGIPSPWLQVKAMRALQYFPT----------IEDPSTR 270
Query: 309 KLRVCVSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTS 368
K V + N NA ++V+F L LD E +S V L + ++
Sbjct: 271 KALFEVLQRILMGTDVVKNVNKNNASHAVLFEALSLVMHLDAEKEMMSQCVALLGKFISV 330
Query: 369 NDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILT 428
+ N RY + + ++ V T ++ I +H ++++ LK + D+++ R+ +DLL +
Sbjct: 331 REPNIRYLGLENMTRMLMV---TDVQDIIKKHQSQIITSLK-DPDISIRRRALDLLYGMC 386
Query: 429 DVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNT 488
DVSN K +V+ELL L + +F++RE+LS + L E A DL+W+V
Sbjct: 387 DVSNAKDIVEELLQYLS---TAEFSMREELSLKAAILAEKFAPDLSWYVDVILQLIDKAG 443
Query: 489 SIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYASLV--N 546
+D +W R+ Q V NNE L A +Y+ + E++VK ++L EY L+
Sbjct: 444 DFVSDDIWFRVVQFVTNNEDLQPYAASKAREYMDKIAIHETMVKVSAYILGEYGHLLARQ 503
Query: 547 DKVSAGDLFNLFTEKYFQVSNLTKAMILTGMLK-LYHV---EPQLSSVVVKFFQLELNSF 602
SA +LF++ EK VS T ++L+ K L H +P+L V F+ +
Sbjct: 504 PGCSASELFSILHEKLPTVSTPTIPILLSTYAKLLMHAQPPDPELQKKVWAVFKKYESCI 563
Query: 603 DVILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPKTQE------- 655
DV +Q R+ EY ++ F+D +L MP F + + ++ K ++
Sbjct: 564 DVEIQQRAVEYFEL----SKKGPAFMD-VLAEMPKF-PERQSSLIKKAENVEDTADQSAI 617
Query: 656 -LLSLEQPFTSGNTVDSNNKPASLPTPP 682
L + +QP S V ++ +P + PP
Sbjct: 618 KLRAQQQP--SNAIVLADPQPVNGAPPP 643
>CE28680 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 925
Score = 212 bits (540), Expect = 2e-54
Identities = 173/659 (26%), Positives = 318/659 (48%), Gaps = 53/659 (8%)
Query: 9 NNMKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYI 68
+ M+GL +FI+D+R + + +RI EL NIR++F L+GYQ+KKYV K+ +I++
Sbjct: 7 DGMRGLAVFISDIRNCKSKEAELKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFL 66
Query: 69 TTNAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLD 128
N ++ FG + LL S+ ++EK IGY+ + +L ++ +++ + ++ D
Sbjct: 67 LGN-----DIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQ---QSDLMKLIVQGIRND 118
Query: 129 LSSGDANAVSLALNFVGIVGNRD--EIFADNLSETIFGILRSPVSSAILKRKACLAFLTL 186
L+S + V+LAL + +G+R+ E F +L + +L S + +K+ A L L L
Sbjct: 119 LTSRNPVHVNLALQCISNMGSREMVEAFCTDLPK----LLVSGETIDFVKQSAALCILKL 174
Query: 187 IRYKPQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDVNPCLRLIP 246
R P + + RI LL D + G E ++++ +P
Sbjct: 175 FRNSPDSFQPGD------YASRIVHLLNDSH-MGVVTSAASLIEALSKKWP-EEYKGAVP 226
Query: 247 QLAEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQT 306
L ++ D Y F V PW+ CV LL++L + + D
Sbjct: 227 LAISRLSRIVTATYTDLQDYTYYF--VPAPWL---CVKLLRLLQNYPPPD------DPSN 275
Query: 307 LGKLRVCVSHAVSFALASDANPVTK----NAQYSVMFTMLGFACKLDPTNEAISNSVTGL 362
+L C+ ++ A DA K NA+ +V+F + +D + + + L
Sbjct: 276 KARLLECLEGILN--KAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQL 333
Query: 363 CELMTSNDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIID 422
++ + N RY + +C + + +H +++ LK E DV++ ++ +D
Sbjct: 334 GTFLSHRETNLRYLALE---SMCLLATSEFSHDAVKKHQDTIINSLKTERDVSVRQRAVD 390
Query: 423 LLVILTDVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXX 482
LL + D SN +V E+L+ LE + D+++RE++ ++ L E +A D W+V
Sbjct: 391 LLYAMCDRSNANQIVAEMLAYLE---TADYSIREEMVLKVAILAEKYATDYTWYVDVILK 447
Query: 483 XXXXNTSIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYA 542
++ VW R+ QIVVN E + A + + + L P E++VK G ++L E+
Sbjct: 448 LIRIAGDYVSEEVWYRVIQIVVNREDVQGYAAKTVFEALQRPACHENMVKVGGYILGEFG 507
Query: 543 SLV--NDKVSAGDLFNLFTEKYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQLE-- 598
+ + +++ +A F L K+ S T+ ++LT +K ++ P++ +V + FQ +
Sbjct: 508 NFIAGDERSTAKIQFELLHSKFHLCSITTRCLLLTTYIKFCNLFPEIKPLVQQVFQTDHN 567
Query: 599 LNSFDVILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPKTQELL 657
L + D LQ RS EYL Q +K+ + +L MP FA K++ +++KL K++ L
Sbjct: 568 LRNPDAELQQRSIEYL---QMTKLASNDVLATILEVMPAFA-EKESSLLAKLKKSKPQL 622
>Hs19913416 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 955
Score = 210 bits (535), Expect = 7e-54
Identities = 173/657 (26%), Positives = 317/657 (47%), Gaps = 59/657 (8%)
Query: 9 NNMKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYI 68
+ M+GL +FI+D+R + + +RI EL NIR++F L+GY +KKYV K+ +I++
Sbjct: 8 DGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFL 67
Query: 69 TTNAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTIS-CLKL 127
+ ++ FG + LL S+ ++EK IGY+ + +L N NS L + I+ +K
Sbjct: 68 LGH-----DIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNS----NSELIRLINNAIKN 118
Query: 128 DLSSGDANAVSLALNFVGIVGNRD--EIFADNLSETIFGILRSPVSSAILKRKACLAFLT 185
DL+S + + LAL+ + VG+R+ E FA ++ IL + S +K+ A L L
Sbjct: 119 DLASRNPTFMCLALHCIANVGSREMGEAFAADIPR----ILVAGDSMDSVKQSAALCLLR 174
Query: 186 LIRYKPQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREI--DVNPCLR 243
L + P ++ E W R+ LL D++ G + ++ D C+
Sbjct: 175 LYKASPDLVPMGE------WTARVVHLLNDQH-MGVVTAAVSLITCLCKKNPDDFKTCVS 227
Query: 244 L-IPQLAEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNI 302
L + +L+ I+ + Q DY + V PW+ + LLQ
Sbjct: 228 LAVSRLSRIVSSASTDLQ------DYTYYFVPAPWLSVKLLRLLQCYPPPE--------- 272
Query: 303 DQQTLGKLRVCVSHAVSFALASDANPVTK--NAQYSVMFTMLGFACKLDPTNEAISNSVT 360
D G+L C+ ++ A + + NA+ +++F + D + +
Sbjct: 273 DAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACN 332
Query: 361 GLCELMTSNDLNTRYSTFDLLIKICKVNGT-TAIKTIQNEHLTRLVDMLKRESDVTLLRK 419
L + + + N RY + + + + A+KT H+ +++ LK E DV++ ++
Sbjct: 333 QLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKT----HIDTVINALKTERDVSVRQR 388
Query: 420 IIDLLVILTDVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXX 479
DLL + D SN K +V E+L LE + D+A+RE++ ++ L E +A D +W+V
Sbjct: 389 AADLLYAMCDRSNAKQIVSEMLRYLE---TADYAIREEIVLKVAILAEKYAVDYSWYVDT 445
Query: 480 XXXXXXXNTSIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLA 539
++ VW R+ QIV N + + A + + + L AP E++VK G ++L
Sbjct: 446 ILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILG 505
Query: 540 EYASLV--NDKVSAGDLFNLFTEKYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQL 597
E+ +L+ + + S F+L K+ S T+A++L+ +K ++ P+ + + +
Sbjct: 506 EFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRA 565
Query: 598 --ELNSFDVILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPK 652
+L + DV LQ R+ EYL + S + + +L MPPF +++ I++KL +
Sbjct: 566 GSQLRNADVELQQRAVEYLTL---SSVASTDVLATVLEEMPPF-PERESSILAKLKR 618
>Hs19913414 [U] KOG1077 Vesicle coat complex AP-2 alpha subunit
Length = 977
Score = 210 bits (535), Expect = 7e-54
Identities = 173/657 (26%), Positives = 317/657 (47%), Gaps = 59/657 (8%)
Query: 9 NNMKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYI 68
+ M+GL +FI+D+R + + +RI EL NIR++F L+GY +KKYV K+ +I++
Sbjct: 8 DGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFL 67
Query: 69 TTNAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTIS-CLKL 127
+ ++ FG + LL S+ ++EK IGY+ + +L N NS L + I+ +K
Sbjct: 68 LGH-----DIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNS----NSELIRLINNAIKN 118
Query: 128 DLSSGDANAVSLALNFVGIVGNRD--EIFADNLSETIFGILRSPVSSAILKRKACLAFLT 185
DL+S + + LAL+ + VG+R+ E FA ++ IL + S +K+ A L L
Sbjct: 119 DLASRNPTFMCLALHCIANVGSREMGEAFAADIPR----ILVAGDSMDSVKQSAALCLLR 174
Query: 186 LIRYKPQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREI--DVNPCLR 243
L + P ++ E W R+ LL D++ G + ++ D C+
Sbjct: 175 LYKASPDLVPMGE------WTARVVHLLNDQH-MGVVTAAVSLITCLCKKNPDDFKTCVS 227
Query: 244 L-IPQLAEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNI 302
L + +L+ I+ + Q DY + V PW+ + LLQ
Sbjct: 228 LAVSRLSRIVSSASTDLQ------DYTYYFVPAPWLSVKLLRLLQCYPPPE--------- 272
Query: 303 DQQTLGKLRVCVSHAVSFALASDANPVTK--NAQYSVMFTMLGFACKLDPTNEAISNSVT 360
D G+L C+ ++ A + + NA+ +++F + D + +
Sbjct: 273 DAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACN 332
Query: 361 GLCELMTSNDLNTRYSTFDLLIKICKVNGT-TAIKTIQNEHLTRLVDMLKRESDVTLLRK 419
L + + + N RY + + + + A+KT H+ +++ LK E DV++ ++
Sbjct: 333 QLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKT----HIDTVINALKTERDVSVRQR 388
Query: 420 IIDLLVILTDVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXX 479
DLL + D SN K +V E+L LE + D+A+RE++ ++ L E +A D +W+V
Sbjct: 389 AADLLYAMCDRSNAKQIVSEMLRYLE---TADYAIREEIVLKVAILAEKYAVDYSWYVDT 445
Query: 480 XXXXXXXNTSIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLA 539
++ VW R+ QIV N + + A + + + L AP E++VK G ++L
Sbjct: 446 ILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILG 505
Query: 540 EYASLV--NDKVSAGDLFNLFTEKYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQL 597
E+ +L+ + + S F+L K+ S T+A++L+ +K ++ P+ + + +
Sbjct: 506 EFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRA 565
Query: 598 --ELNSFDVILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPK 652
+L + DV LQ R+ EYL + S + + +L MPPF +++ I++KL +
Sbjct: 566 GSQLRNADVELQQRAVEYLTL---SSVASTDVLATVLEEMPPF-PERESSILAKLKR 618
>Hs18104998 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 825
Score = 118 bits (295), Expect = 5e-26
Identities = 151/704 (21%), Positives = 293/704 (41%), Gaps = 85/704 (12%)
Query: 14 LQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITTNAG 73
L+ I +R + E IQ E IR+ F ++ N Y R + VAK+ Y+++
Sbjct: 7 LRELIRTIRTARTQAEEREMIQKECAAIRSSFREED--NTY-RCRNVAKLLYMHMLGYPA 63
Query: 74 MVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLSSGD 133
FG +C +L+ S F++K IGY+ LL + R V +C+K DL+
Sbjct: 64 H-----FGQLECLKLIASQKFTDKRIGYLGAMLLLDE---RQDVHLLMTNCIKNDLNHST 115
Query: 134 ANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYKPQI 193
LAL +G +G+ + +L+ + +L++ S++ L++KA L + +IR P++
Sbjct: 116 QFVQGLALCTLGCMGSSE--MCRDLAGEVEKLLKT--SNSYLRKKAALCAVHVIRKVPEL 171
Query: 194 LTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDV----NPCLRLIPQLA 249
+ +++ LL ++N E R D+ L+L+PQL
Sbjct: 172 M--------EMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKSLQLVPQLV 223
Query: 250 EILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLGK 309
IL + S ++ SG+S+P++ + LL++L G N D
Sbjct: 224 RILKNLIM----SGYSPEHDVSGISDPFLQVRILRLLRIL---------GRNDDDS---- 266
Query: 310 LRVCVSHAVSFALASDA--NPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMT 367
S A++ LA A +KN ++++ + + + ++ L +
Sbjct: 267 -----SEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLL 321
Query: 368 SNDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVIL 427
+ND N RY L+K + + H + +VD LK + DV++ R+ ++L L
Sbjct: 322 NNDKNIRYVALTSLLKTVQTDHNAV-----QRHRSTIVDCLK-DLDVSIKRRAMELSFAL 375
Query: 428 TDVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXN 487
+ +N + +++ELL L+ S + + D + I E +A W +
Sbjct: 376 VNGNNIRGMMKELLYFLD---SCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTA 432
Query: 488 TSIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYAS-LVN 546
S D + Q++ N+ +H + L + + LV+ + + EY LV+
Sbjct: 433 GSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVS 492
Query: 547 DKVSAGDLFNLFTEKYFQV----------SNLTKAMILTGMLKLYHVEPQLSSVVVKFFQ 596
+ + + ++ + +++T+ LT ++KL + + K
Sbjct: 493 GQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVS 552
Query: 597 LELNSFDVILQTRSYEYLKII-QYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPKTQE 655
+ +S DV LQ R+ EY + +Y M + +P M ++ T+I+ +T+
Sbjct: 553 IYGSSIDVELQQRAVEYNALFKKYDHMRSALL--ERMPVMEKVTTNGPTEIVQTNGETEP 610
Query: 656 LLSLEQPFTSG-----------NTVDSNNKPASLPTPPRSRKNN 688
+P SG + + N+ +PT P S+ ++
Sbjct: 611 APLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSS 654
>At1g23900 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 876
Score = 115 bits (288), Expect = 3e-25
Identities = 133/631 (21%), Positives = 270/631 (42%), Gaps = 63/631 (9%)
Query: 14 LQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITTNAG 73
L+ I +RA + E ++ E +IR + + + R + +AK+ +I++
Sbjct: 10 LRDMIRAIRACKTAAEERAVVRKECADIRALINED---DPHDRHRNLAKLMFIHM----- 61
Query: 74 MVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLSSGD 133
+ FG +C +L+ S F EK IGY+ L LL + R VL + LK DL+ +
Sbjct: 62 LGYPTHFGQMECLKLIASPGFPEKRIGYLGLMLLLDE---RQEVLMLVTNSLKQDLNHSN 118
Query: 134 ANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYKPQI 193
V LAL +G + + + A +L+ + +++ +++KA L +IR P +
Sbjct: 119 QYVVGLALCALGNICSAE--MARDLAPEVERLIQ--FRDPNIRKKAALCSTRIIRKVPDL 174
Query: 194 LTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDVNPCLRLIPQLAEILH 253
N ++ +LL +++ E + R + E L
Sbjct: 175 AEN--------FVNAAASLLKEKHHGVLITGVQLCYELCTINDEALEYFRT--KCTEGLI 224
Query: 254 ECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLGKLRVC 313
+ L NSA +Y +G+++P++ + LL+VL + + S++ L ++
Sbjct: 225 KTLRDITNSAYQPEYDVAGITDPFLHIRLLRLLRVLGQGDAD---ASDLMTDILAQV--- 278
Query: 314 VSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTSNDLNT 373
A +++N KNA +V++ + ++ TN ++ L +++ D N
Sbjct: 279 -------ATKTESN---KNAGNAVLYECVETIMAIEDTNSLRVLAINILGRFLSNRDNNI 328
Query: 374 RYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILTDVSNF 433
RY ++L+K + H +++ +K + D ++ ++ ++L+ +L + +N
Sbjct: 329 RYVALNMLMKAITFDDQAV-----QRHRVTILECVK-DPDASIRKRALELVTLLVNENNV 382
Query: 434 KFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNTSIKND 493
+ +EL+ LE D +EDLS +I ++E + + W++ D
Sbjct: 383 TQLTKELIDYLEIS---DEDFKEDLSAKICFIVEKFSPEKLWYIDQMLKVLCEAGKFVKD 439
Query: 494 HVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYASLVNDKV---- 549
VW + ++ N LH L + + E+LV+ V+ + EY L+ + V
Sbjct: 440 DVWHALIVVISNASELHGYTVRALYKSVLTYSEQETLVRVAVWCIGEYGDLLVNNVGMLG 499
Query: 550 -------SAGDLFNLFTEKYFQVSN--LTKAMILTGMLKLYHVEPQLSSVVVKFFQLELN 600
+ D ++ + + ++ TKAM L +LKL P +S + +
Sbjct: 500 IEDPITVTESDAVDVIEDAITRHNSDSTTKAMALVALLKLSSRFPSISERIKDIIVKQKG 559
Query: 601 SFDVILQTRSYEYLKIIQYSKMNDMTFIDKL 631
S + +Q R+ EY I+ K + +D++
Sbjct: 560 SLLLEMQQRAIEYNSIVDRHKNIRSSLVDRM 590
>At1g60070 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 867
Score = 111 bits (278), Expect = 5e-24
Identities = 139/621 (22%), Positives = 257/621 (41%), Gaps = 72/621 (11%)
Query: 18 IADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITTNAGMVPE 77
I +RA++ E ++ E IR + Y R + +AK+ +I++ +
Sbjct: 14 IRAIRASKTAAEERAVVRKECAAIRASINEND--QDY-RHRDLAKLMFIHM-----LGYP 65
Query: 78 LLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLSSGDANAV 137
FG +C +L+ S F EK IGY+ L LL + R VL + LK DL+ + V
Sbjct: 66 THFGQMECLKLIASPGFPEKRIGYLGLMLLLDE---RQEVLMLVTNSLKQDLNHTNQYIV 122
Query: 138 SLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYKPQILTNL 197
LAL +G + + + A +L+ + +L+ +++KA L + +IR P + N
Sbjct: 123 GLALCALGNICSAE--MARDLAPEVERLLQ--FRDPNIRKKAALCAIRIIRKVPDLSEN- 177
Query: 198 EDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDVNPCLRLIPQLAEILHECLS 257
+I LL E HG I + + + E L + L
Sbjct: 178 -------FINPGAALL-KEKHHGVLITGVHLCTEICK-VSSEALEYFRKKCTEGLVKTLR 228
Query: 258 KKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLGKLRVCVSHA 317
NS +Y +G+++P++ + LL+VL + + S
Sbjct: 229 DIANSPYSPEYDVAGITDPFLHIRLLKLLRVLGQGDAD------------------ASDC 270
Query: 318 VSFALASDANPV--TKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTSNDLNTRY 375
++ LA A+ KNA ++++ + ++ ++ L + +++ D N RY
Sbjct: 271 MNDILAQVASKTESNKNAGNAILYECVQTIMSIEENGGLRVLAINILGKFLSNRDNNIRY 330
Query: 376 STFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILTDVSNFKF 435
++L++ V+ H +++ +K +SD ++ ++ ++L+ +L + +N K
Sbjct: 331 VALNMLMRSLTVDSQAV-----QRHRATILECVK-DSDASIQKRALELIYLLVNENNVKP 384
Query: 436 VVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNTSIKNDHV 495
+ +EL+ LE DF + DL+ +I ++E A + W++ + + V
Sbjct: 385 LAKELIEYLEV-SEQDF--KGDLTAKICSIVEKFAPEKIWYIDQMLKVLSEAGTYVKEDV 441
Query: 496 WKRICQIVVNNEPLHKLACEHLIDYLH-----APNVAESLVKAGVFLLAEYASLVNDKVS 550
W + ++ N LH L LH E+LV+ ++ + EYA L+ +
Sbjct: 442 WHALIVVITNAPDLHGYTVRALYRALHTSFEQVDISLETLVRVAIWCIGEYADLLVNNAG 501
Query: 551 AGDLFNLFTE-------------KYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQL 597
DL + T K+ TKAM L +LK+ P S V
Sbjct: 502 MLDLEDPITVTESDAVDVVENAIKHHLSDVTTKAMALIALLKISSRFPSCSERVKSIIGQ 561
Query: 598 ELNSFDVILQTRSYEYLKIIQ 618
SF + LQ RS E+ +IQ
Sbjct: 562 NKGSFVLELQQRSLEFSSVIQ 582
>SPCP1E11.06 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 865
Score = 105 bits (262), Expect = 3e-22
Identities = 171/822 (20%), Positives = 324/822 (38%), Gaps = 105/822 (12%)
Query: 11 MKGLQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITT 70
M L+ FI +RA++ T E I E IR Q S + R+K VAK+ Y+++
Sbjct: 30 MSSLKSFIKAVRASKTTAEEHTTILKESAQIRKNIRQGSN-DMRMRRKNVAKLLYLFL-- 86
Query: 71 NAGMVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLS 130
+ FG +C +LL SS F +K +GY+ LL + VL + L+ DL
Sbjct: 87 ---LGEPTHFGQIECLKLLSSSRFMDKRLGYLAAMLLLDE---NQEVLTLLTNSLQNDLK 140
Query: 131 SGDANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYK 190
S D V LAL+ G V + A +LS I + + + +KA L L +I+ +
Sbjct: 141 SRDKFIVGLALSAFGNVAGPE--LARDLSNDIAELCSN--HHNYISKKAVLCALRVIQKE 196
Query: 191 PQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDVNPCL--RLIPQL 248
P + +L+IE+ LL ++ HG F +NP L R Q
Sbjct: 197 PDL--------ESLYIEKTDELLHSKS-HGVLMAALA---FAISACKINPSLISRFESQA 244
Query: 249 AEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLG 308
++++ + + S +++ +S+P++ + L +L +N + D+ +
Sbjct: 245 DDLIYR-IRQLSTSTYSSEHNIGNISDPFLQVKILQFLSILGQNNPK-----IYDKMSDL 298
Query: 309 KLRVCVSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTS 368
+VC + ++NA ++++ + L+ + V L + + +
Sbjct: 299 LAQVCTN-----------TDSSRNAGNAILYQAVRTILDLNSDSSLRVLGVNILAKFLGN 347
Query: 369 NDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILT 428
D NTRY ++L K+ + A++ ++ L L D+ D ++ + ++L L
Sbjct: 348 RDNNTRYVALNML-KLVVNSEENAVQRHRSTILACLNDV-----DSSIQSRALELSTFLV 401
Query: 429 DVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNT 488
+ +N +F+V+ELLS L+ ++ LR + I + A + W
Sbjct: 402 NEANVRFMVRELLSFLD---NVSDELRGSTAQYITEVTNAFAPNKRWHFDTLLRVFKSAG 458
Query: 489 SIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYASL---- 544
+ ++ +++ + LH+ A L L E+L + +++ EY +
Sbjct: 459 NFVSESTLSTFLRLIASAPELHEYAVVKLYAALKEDVSQEALTLSAFWVIGEYGQMLLSP 518
Query: 545 ---------VNDKVSAGDLFNLFTEKYFQVSNLTKAMILTGMLKLYHVEPQL-----SSV 590
+ VS D+ ++ E + V ++ G+ L + +L +S
Sbjct: 519 TMNFDDDQTLPHSVSESDIVDIIEEVFNSVEASRYIIVQYGLFALTKLSARLGSSSTASR 578
Query: 591 VVKFFQLELNSFDVILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFAS---------S 641
+ K + + +Q RS E+ I+ SK++ P PP +
Sbjct: 579 IDKIIYSYKRNKNTEVQQRSVEFHLILNDSKLSKTILEPTPAPLPPPRTTPYQNAEQKLK 638
Query: 642 KDTDIMSKLPKTQELLSLEQPFTSGNTVDSNNKPASLPTPPRSRKNNKLYHSQQLTPGWE 701
+ + ++ ++ ELL L G T S +P P ++T +
Sbjct: 639 ANKHVEKRVQESNELLDL-----IGLTTPSVAEPLETPV-------------DEMTQSPQ 680
Query: 702 SGFKRMLIHTQGVFYQDTLVSVLFRVETKEEQP----STSKITFTYVNKSDWEITGLS-C 756
S R ++ ++D L LF QP ++S + + + LS
Sbjct: 681 SSLSRAPSTSKKSHFEDIL--GLFASPAPSAQPVDSLASSFASLDFNASASQPSNNLSLL 738
Query: 757 EIIPLRADNNPPYVLQVLQSPDSKLAPSNGRTSYTFEITTRF 798
IP + + PP V+ L PS ++ T I +F
Sbjct: 739 SSIPSTSKSYPPIVVFDKHDVTLTLVPSKEESTKTAVIEAKF 780
>Hs4503843 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 785
Score = 95.9 bits (237), Expect = 3e-19
Identities = 174/808 (21%), Positives = 326/808 (39%), Gaps = 113/808 (13%)
Query: 14 LQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITTNAG 73
LQ I ++R + + IQ E +IR F ++ R + +AK+ Y+++
Sbjct: 8 LQDLIEEIRGAKTQAQEREVIQKECAHIRASFRDGDPVH---RHRQLAKLLYVHMLGYPA 64
Query: 74 MVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFN-----HAVVRNSVLEKTISCLKLD 128
FG +C +L+ SS F++K +GY+ LL + H ++ NS+ K D
Sbjct: 65 H-----FGQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSI--------KND 111
Query: 129 LSSGDANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIR 188
LS G LAL + +G+ + +L+ + +L P S +++KA L + +IR
Sbjct: 112 LSQGIQPVQGLALCTLSTMGSAE--MCRDLAPEVEKLLLQP--SPYVRKKAILTAVHMIR 167
Query: 189 YKPQILTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIARE-IDVNPCLRLIPQ 247
P++ ++++ LL + + E R + +++PQ
Sbjct: 168 KVPEL--------SSVFLPPCAQLLHERHHGILLGTITLITELCERSPAALRHFRKVVPQ 219
Query: 248 LAEILHECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTL 307
L IL ++ ++ ++ SGVS+P++ + LL++L ++ E+ +T+
Sbjct: 220 LVHILRTLVTMGYST----EHSISGVSDPFLQVQILRLLRILGRNHEES-------SETM 268
Query: 308 GKLRVCVSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMT 367
L A + ++NA +V+F + + +V L +
Sbjct: 269 NDL---------LAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLL 319
Query: 368 SNDLNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVIL 427
++D N RY L+++ + + + H +V+ L RE+D +L R+ ++L + L
Sbjct: 320 NSDRNIRYVALTSLLRLVQSDHSAV-----QRHRPTVVECL-RETDASLSRRALELSLAL 373
Query: 428 TDVSNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFV-XXXXXXXXX 486
+ SN + ++QEL + LE S LR D + I E A W +
Sbjct: 374 VNSSNVRAMMQELQAFLE---SCPPDLRADCASGILLAAERFAPTKRWHIDTILHVLTTA 430
Query: 487 NTSIKNDHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNVAESLVKAGVFLLAEYASLVN 546
T +++D V + Q++ + LH + L + L + LV+ + + EY L+
Sbjct: 431 GTHVRDDAV-ANLTQLIGGAQELHAYSVRRLYNALAEDISQQPLVQVAAWCIGEYGDLLL 489
Query: 547 D---------KVSAGDLFNLFTEKYFQVS---NLTKAMILTGMLKLYHVEPQLSSVVVKF 594
+V ++ L EK Q T+ LT ++KL ++ + +
Sbjct: 490 AGNCEEIEPLQVDEEEVLALL-EKVLQSHMSLPATRGYALTALMKLSTRLCGDNNRIRQV 548
Query: 595 FQLELNSFDVILQTRSYEYLKII-QYSKM-----NDMTFIDKLLPGMPPFA-SSKDTDIM 647
+ + DV LQ R+ EY + +Y M M +++ P A SK+ +
Sbjct: 549 VSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVERDGPQADEEAKESKEAAQL 608
Query: 648 SKL------PKTQELLSLEQPFTSGNTVDSNNKPASLPTPPRSRKNNKLYHSQQL--TPG 699
S+ P+ +LL L G + D + P P+P L H L P
Sbjct: 609 SEAAPVPTEPQASQLLDL-LDLLDGASGDVQHPPHLDPSP-----GGALVHLLDLPCVPP 662
Query: 700 WESGFKRMLIHTQGVFYQDTLVSVLFRVETKEEQPSTSKITFTYVNKSDWEITGLSCEII 759
+ + + ++ V + E P+ IT T N S+ ++T C+
Sbjct: 663 PPAPIPDLKV------FEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAA 716
Query: 760 PLRADNNPPYVLQV-LQSPDSKLAPSNG 786
P LQ+ LQ+P P+ G
Sbjct: 717 -------VPKSLQLQLQAPSGNTVPARG 737
>7291008 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 951
Score = 91.3 bits (225), Expect = 7e-18
Identities = 132/635 (20%), Positives = 259/635 (40%), Gaps = 71/635 (11%)
Query: 14 LQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITTNAG 73
L+ I +RA + E + E IR+ F ++ + R + +AK+ YI++
Sbjct: 23 LRDLIRQIRAARTAAEERAVVNKECAYIRSTFREEDSV---WRCRNIAKLLYIHMLGYPA 79
Query: 74 MVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLSSGD 133
FG +C +L S+ F++K IGY+ LL + R V +CLK DL+S
Sbjct: 80 H-----FGQLECLKLTASTRFTDKRIGYLGAMLLLDE---RQDVHLLITNCLKNDLNSST 131
Query: 134 ANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYKPQI 193
V LAL +G + + + A +L+ + +++SP + +++KA L +IR P++
Sbjct: 132 QFVVGLALCTLGAIASPE--MARDLASEVERLMKSP--NTYIRKKATLCAFRVIRRVPEL 187
Query: 194 LTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREID-VNPCLRLIPQLAEIL 252
+ +++ +LL ++N E D + +++P L IL
Sbjct: 188 M--------EIFLPATRSLLSEKNHGILITGVTLITEMCENSSDTLMHFKKIVPNLVRIL 239
Query: 253 HECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLGKLRV 312
+ + +D SGVS+P++ + LL++L ++ +
Sbjct: 240 KNLILGGYSPEHDV----SGVSDPFLQVKILRLLRILGHNDPD----------------- 278
Query: 313 CVSHAVSFALASDA--NPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTSND 370
S A++ LA A +KN ++++ + + +V L + ++D
Sbjct: 279 -ASEAMNDILAQVATNTETSKNVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSD 337
Query: 371 LNTRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILTDV 430
N RY + L++ + T+A++ H T +++ LK + DV++ R+ ++L L +
Sbjct: 338 KNIRYVALNTLLRTVHAD-TSAVQ----RHRTTILECLK-DPDVSIRRRAMELSFALINA 391
Query: 431 SNFKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNTSI 490
N + + +ELL LE D + S + E ++ W + +
Sbjct: 392 QNIRTMTKELLLFLE---KADAEFKAQCSSGMILAAERYSPTTRWHLDTQLSVLIAAGNY 448
Query: 491 KNDHVWKRICQIVVNNE-PLHKLACEHLIDYLHAPNVAES---LVKAGVFLLAEYASLVN 546
D V Q+V ++ P + L N E L++ V+ + EY L
Sbjct: 449 VRDDVVSSTIQLVSSSPVPEQTYITNRFWESLQVANHCEDKQPLLQVAVWAIGEYGDLFM 508
Query: 547 --------DKVSAGDLFNLFTE--KYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQ 596
++ + DL ++ + QVS +K L + KL Q +
Sbjct: 509 YGANEDEFERPTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTRLQQCVEEIQALIT 568
Query: 597 LELNSFDVILQTRSYEYLKIIQYSKMNDMTFIDKL 631
+ +V LQ R E+ ++ + K ++K+
Sbjct: 569 SFGSHLNVDLQQRGVEFTQLFGHYKHLRPPLLEKM 603
>CE25176 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 894
Score = 88.6 bits (218), Expect = 4e-17
Identities = 134/650 (20%), Positives = 259/650 (39%), Gaps = 66/650 (10%)
Query: 14 LQLFIADLRANQKTKEHARRIQTELQNIRTQFTQKSGLNGYQRKKYVAKMAYIYITTNAG 73
L+ I +RA + E + E NIR F + + + +AK+ YI++
Sbjct: 29 LRDLIRQVRAARTMAEERAVVDRESANIRESFRDD---DSPWKCRNIAKLLYIHMLGYPA 85
Query: 74 MVPELLFGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLSSGD 133
FG +C +L+ F++K IGY+ LL + R+ V + LK DL+
Sbjct: 86 H-----FGQMECMKLVAHPRFTDKRIGYLGAMLLLDE---RSEVHMLVTNSLKNDLTCST 137
Query: 134 ANAVSLALNFVGIVGNRDEIFADNLSETIFGILRSPVSSAILKRKACLAFLTLIRYKPQI 193
LAL +G + + + +L+ + I++ ++A LK+KA L ++R P++
Sbjct: 138 QFVSGLALCTLGSICSAE--MCRDLANEVEKIIKQ--NNAYLKKKAALCAFRIVRKVPEL 193
Query: 194 LTNLEDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDV-NPCLRLIPQLAEIL 252
+ ++I +LLG++N E + DV N +L+P L IL
Sbjct: 194 M--------EVFIPCTRSLLGEKNHGVLMGATTLVTEMCEKSPDVLNHFKKLVPNLVRIL 245
Query: 253 HECLSKKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLGKLRV 312
L S ++ +G+S+P++ + LL+VL D+ +RV
Sbjct: 246 KNLLM----SGYSPEHDVTGISDPFLQVKILRLLRVLGKDD----------------VRV 285
Query: 313 CVSHAVSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTSNDLN 372
A + KN ++++ + ++ + +V L + + D N
Sbjct: 286 TEEMNDILAQVATNTETAKNVGNAILYETVLTIMEIKSESGLRILAVNILGRFLLNTDKN 345
Query: 373 TRYSTFDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILTDVSN 432
RY + L+K V+ + +Q H +V+ LK + D+++ ++ ++L L + +N
Sbjct: 346 IRYVALNTLLKTVHVD----YQAVQ-RHRNVVVECLK-DPDISIRKRAMELCFALMNRTN 399
Query: 433 FKFVVQELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNTSIKN 492
+ +E+L LE + D + + + ++ E ++ + W +
Sbjct: 400 IAIMTKEVLIFLE---TADAEFKSECASRMYIATERYSPNHEWHLDTMITVLRLAGKYVP 456
Query: 493 DHVWKRICQIVVNNEPLHKLACEHLIDYLHAPNV-AESLVKAGVFLLAEYASLV------ 545
D V + Q++ NE L A L + A+ L++ + + E+ L+
Sbjct: 457 DEVVSCMIQMISANEQLQSYAVSQLYHAAQKDAINAQPLLQVAFWTIGEFGDLLLQPTDV 516
Query: 546 -NDKVSAGDLFNLFTE--KYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQLELNSF 602
+ +S D+ +F S TK +T + KL + ++
Sbjct: 517 DSTPISENDVVGVFESVLPSALTSLWTKCYGVTALAKLGTRFQSTGDRIGALVRMNQAHI 576
Query: 603 DVILQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPK 652
+ LQ RS E+ I+ + D+ F G P+ K S L K
Sbjct: 577 QLELQQRSVEFNVIL---NLGDLRFKIWFFLGKIPYFLVKKIFFFSILGK 623
>Hs6671551 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 1137
Score = 67.8 bits (164), Expect = 8e-11
Identities = 119/631 (18%), Positives = 249/631 (38%), Gaps = 83/631 (13%)
Query: 80 FGLDQCFQLLKSSNFSEKWIGYMTLELLFNHAVVRNSVLEKTISCLKLDLSSGDANAVSL 139
FG +L + N EK +GY+ + L + + + +L ++ + DL S + V +
Sbjct: 96 FGYIHAIKLAQQGNLLEKRVGYLAVSLFLHES---HELLLLLVNTVVKDLQSTNLVEVCM 152
Query: 140 ALNFVGIVGNRDEIFADNLSETIFGILRSPV--SSAILKRKACLAFLTLIRYKPQILTNL 197
AL V +IF + + ++ + S I++RKA LA P + ++
Sbjct: 153 ALTVVS------QIFPREMIPAVLPLIEDKLQHSKEIVRRKAVLALYKFHLIAPNQVQHI 206
Query: 198 EDNKRTLWIERITTLLGDENDHGXXXXXXXXXEFIAREIDVNPCLRLIPQLAEILHECLS 257
R +R D G + +E + + L IL + +
Sbjct: 207 HIKFRKALCDR---------DVGVMAASLHIYLRMIKE-NSSGYKDLTGSFVTILKQVVG 256
Query: 258 KKQNSANDADYQFSGVSNPWIVGNCVSLLQVLVSDNGENLIGSNIDQQTLGKLRVCVSHA 317
K ++ + V PW+ + LL++L L+G + DQ+T + + +
Sbjct: 257 GKL----PVEFNYHSVPAPWLQ---IQLLRIL------GLLGKD-DQRTSELMYDVLDES 302
Query: 318 VSFALASDANPVTKNAQYSVMFTMLGFACKLDPTNEAISNSVTGLCELMTSNDLNTRYST 377
+ A + N Y+++F + + P +E + + + + + S +N +Y
Sbjct: 303 LRRA------ELNHNVTYAILFECVHTVYSIYPKSELLEKAAKCIGKFVLSPKINLKYLG 356
Query: 378 FDLLIKICKVNGTTAIKTIQNEHLTRLVDMLKRESDVTLLRKIIDLLVILTDVSNFKFVV 437
L + + + T A+ +H +++ L D + R+ ++LL +T+ N +V
Sbjct: 357 LKALTYVIQQDPTLAL-----QHQMTIIECLDHP-DPIIKRETLELLYRITNAQNITVIV 410
Query: 438 QELLSALEAHKSMDFALREDLSFQIERLIELHADDLNWFVXXXXXXXXXNTSIKNDHVWK 497
Q++L L H+S + + +L +I L E +A D WF+ + + +
Sbjct: 411 QKMLEYL--HQSKEEYVIVNLVGKIAELAEKYAPDNAWFIQTMNAVFSVGGDVMHPDIPN 468
Query: 498 RICQIV-------VNNEPLHKLACEHLIDYLHAPNV--AESLVKAGVFLLAEYASLVNDK 548
+++ ++ L A + + L NV + ++ ++L EY+ L++ +
Sbjct: 469 NFLRLLAEGFDDETEDQQLRLYAVQSYLTLLDMENVFYPQRFLQVMSWVLGEYSYLLDKE 528
Query: 549 VS---AGDLFNLFTEKYFQVSNLTKAMILTGMLKLYHVEPQLSSVVVKFFQLELNSFDVI 605
L+ L VS+ TKA ++ + KL + S+ V + S D
Sbjct: 529 TPEEVIAKLYKLLMND--SVSSETKAWLIAAVTKLTS-QAHSSNTVERLIHEFTISLDTC 585
Query: 606 LQTRSYEYLKIIQYSKMNDMTFIDKLLPGMPPFASSKDTDIMSKLPKTQELLSLEQPFTS 665
++ ++E LK + + ++ + +P S +D + + L F
Sbjct: 586 MRQHAFE-LKHLHEN-------VELMKSLLPVDRSCEDLVVDASL-----------SFLD 626
Query: 666 GNTVDSNNKPASLPTPPRSRKNNKLYHSQQL 696
G + ++ A+ PP R+ KL + L
Sbjct: 627 GFVAEGLSQGAAPYKPPHQRQEEKLSQEKVL 657
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.135 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,610,006
Number of Sequences: 60738
Number of extensions: 2225127
Number of successful extensions: 5894
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 5806
Number of HSP's gapped (non-prelim): 20
length of query: 952
length of database: 30,389,216
effective HSP length: 116
effective length of query: 836
effective length of database: 23,343,608
effective search space: 19515256288
effective search space used: 19515256288
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)