ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3145 good H KOG1284 Coenzyme transport and metabolism Bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2butanone-4-phosphate synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3145 1083366 1082455 -304
(304 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBL033c [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihydr... 456 e-128
SPAP27G11.09c [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-... 316 3e-86
At5g59750 [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihy... 137 1e-32
At5g64300 [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihy... 133 3e-31
At2g22450 [H] KOG1284 Bifunctional GTP cyclohydrolase II/34-dihy... 65 2e-10
>YBL033c [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 345
Score = 456 bits (1174), Expect = e-128
Identities = 223/289 (77%), Positives = 249/289 (85%), Gaps = 4/289 (1%)
Query: 8 LPKVQCIARARIPTVQGPDIFLHLYQNDRDNKEHLAIVFGENIRSRSLFRRNAGETQEER 67
LP VQC+ARARIPT QGPDIFLHLY N+RDNKEHLAIVFGE+IRSRSLFRR ETQ++R
Sbjct: 31 LPLVQCVARARIPTTQGPDIFLHLYSNNRDNKEHLAIVFGEDIRSRSLFRRRQCETQQDR 90
Query: 68 MIRGAYVGKLYPGRVKADVDEKQGLSLSFDEKTGELVVEPNTTW-CDKDTLVRIHSECYT 126
MIRGAY+GKLYPGR AD D++ GL+L FD+ TGEL+ TTW DTLVRIHSECYT
Sbjct: 91 MIRGAYIGKLYPGRTVADEDDRLGLALEFDDSTGELLASKATTWDAHNDTLVRIHSECYT 150
Query: 127 GETAWSARCDCGEQFDRAGKLISVERE--GDIVGGNGHGVIVYLRQEGRGIGLGEKLKAY 184
GE AWSARCDCGEQFDRAG+LI+ + E +I GGNGHGVIVYLRQEGRGIGLGEKLKAY
Sbjct: 151 GENAWSARCDCGEQFDRAGRLIACDHEPTSNIKGGNGHGVIVYLRQEGRGIGLGEKLKAY 210
Query: 185 NLQDLGADTVQANLLLKHPADGRDFSIGRAILIDLGISNVRLLTNNPDKVAQVEQAPYLH 244
NLQDLGADTVQANL+LKHP D RDFS+G+AIL+DLGI NVRLLTNNP+K+ QV+ APYL
Sbjct: 211 NLQDLGADTVQANLMLKHPVDARDFSLGKAILLDLGIGNVRLLTNNPEKIKQVDHAPYLK 270
Query: 245 CVERVPMVPLSWSGNHKDGIHSKEIEGYLRTKIERMGHLLQKPLTLHTN 293
CVERVPMVP+ W+ N +GI SKEIEGYLRTKIERMGHLL +PL LHTN
Sbjct: 271 CVERVPMVPIHWT-NSSEGIDSKEIEGYLRTKIERMGHLLTEPLKLHTN 318
>SPAP27G11.09c [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 326
Score = 316 bits (809), Expect = 3e-86
Identities = 169/281 (60%), Positives = 204/281 (72%), Gaps = 20/281 (7%)
Query: 8 LPKVQCIARARIPTVQGPDIFLHLYQNDRDNKEHLAIVFGENIRSRSLFRRNAGETQEER 67
LPKV+C+ RARIPTV+G +IFLHLY+ND DNKEHLAIVFG+ IRS SL GET+ +R
Sbjct: 63 LPKVRCVVRARIPTVKGTEIFLHLYKNDFDNKEHLAIVFGQQIRSDSLDAVQEGETEMDR 122
Query: 68 MIRGAYVGKLYPGRVKADVDEKQGLSLSFDEKTGELVVEPNTTWCDKDTLVRIHSECYTG 127
M+RGAYVG LYPGR + +D ++ + T E E T + LVRIHSECYTG
Sbjct: 123 MVRGAYVGTLYPGRKSSYID------VNSSKTTEEQKEEARKT--NFVPLVRIHSECYTG 174
Query: 128 ETAWSARCDCGEQFDRAGKLISVEREGDIVGGNGHGVIVYLRQEGRGIGLGEKLKAYNLQ 187
ETAWSARCDCGEQ D A +LIS E G+GVI+YLRQEGRGIGL EKLKAYNLQ
Sbjct: 175 ETAWSARCDCGEQLDEAARLISEE---------GNGVIIYLRQEGRGIGLSEKLKAYNLQ 225
Query: 188 DLGADTVQANLLLKHPADGRDFSIGRAILIDLGISNVRLLTNNPDKVAQVE-QAPYLHCV 246
DLG DTVQANLLL+HPADGR +++ A+L+DLG ++RLLTNNP+KV +E + V
Sbjct: 226 DLGNDTVQANLLLQHPADGRSYAVATAMLMDLGQRDIRLLTNNPEKVNSIEGPNKEVRVV 285
Query: 247 ERVPMVPLSWSGNHKDGIHSKEIEGYLRTKIERMGHLLQKP 287
ER+ M+P SW G + GI S E+ YL+TKIE+MGHLL P
Sbjct: 286 ERISMIPKSWRG--EKGIESAEVVLYLKTKIEKMGHLLDLP 324
>At5g59750 [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 508
Score = 137 bits (346), Expect = 1e-32
Identities = 86/184 (46%), Positives = 110/184 (59%), Gaps = 28/184 (15%)
Query: 114 KDTLVRIHSECYTGETAWSARCDCGEQFDRAGKLISVEREGDIVGGNGHGVIVYLR-QEG 172
+D LVR+HSEC TG+ SARCDCG Q D A +LI E G GV+VYLR EG
Sbjct: 347 EDILVRVHSECLTGDIFGSARCDCGNQLDLAMELIEKE---------GRGVVVYLRGHEG 397
Query: 173 RGIGLGEKLKAYNLQDLGADTVQANLLLKHPADGRDFSIGRAILIDLGISNVRLLTNNPD 232
RGIGLG KL+AYNLQD G DTVQAN+ L D R++ IG +L D+G+ +RL+TNNP
Sbjct: 398 RGIGLGHKLRAYNLQDEGHDTVQANVELGLSIDSREYGIGAQMLRDIGVRTMRLMTNNPA 457
Query: 233 KVAQVEQAPYLHCVERVPMV-PLSWSGNHKDGIHSKEIEGYLRTKIERMGHLLQKPLTLH 291
K + + L V RVP+V P+ +KE Y+ TK ++MGH+ +
Sbjct: 458 KFTGL-KGYGLAVVGRVPVVTPI-----------TKENRRYMETKRKKMGHIY-----IS 500
Query: 292 TNND 295
NND
Sbjct: 501 DNND 504
>At5g64300 [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 543
Score = 133 bits (335), Expect = 3e-31
Identities = 79/171 (46%), Positives = 105/171 (61%), Gaps = 21/171 (12%)
Query: 114 KDTLVRIHSECYTGETAWSARCDCGEQFDRAGKLISVEREGDIVGGNGHGVIVYLR-QEG 172
+D LVR+HSEC TG+ SARCDCG Q +S+++ + G GV+VYLR EG
Sbjct: 374 QDILVRVHSECLTGDIFGSARCDCGNQL-----ALSMQQ----IEATGRGVLVYLRGHEG 424
Query: 173 RGIGLGEKLKAYNLQDLGADTVQANLLLKHPADGRDFSIGRAILIDLGISNVRLLTNNPD 232
RGIGLG KL+AYNLQD G DTV+AN L P D R++ IG I+ DLG+ ++L+TNNP
Sbjct: 425 RGIGLGHKLRAYNLQDAGRDTVEANEELGLPVDSREYGIGAQIIRDLGVRTMKLMTNNPA 484
Query: 233 KVAQVEQAPYLHCVERVPMVPLSWSGNHKDGIHSKEIEGYLRTKIERMGHL 283
K + + L V RVP++ L +KE + YL TK +MGH+
Sbjct: 485 KYVGL-KGYGLAIVGRVPLLSLI----------TKENKRYLETKRTKMGHM 524
>At2g22450 [H] KOG1284 Bifunctional GTP cyclohydrolase
II/34-dihydroxy-2butanone-4-phosphate synthase
Length = 433
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/119 (34%), Positives = 61/119 (50%), Gaps = 18/119 (15%)
Query: 114 KDTLVRIHSECYTGETAWSARCDCGEQFDRAGKLISVEREGDIVGGNGHGVIVYLR-QEG 172
KD LVR+H+EC T + ++ GK +++ ++ NG GV VYLR E
Sbjct: 309 KDILVRVHAECITDDIFGNSS---------GGKQLAIAMR--LIEENGRGVFVYLRGPES 357
Query: 173 RGIGLGEKLKAYNLQDLGADTVQANLLLKHPADGRDFSIGRAILIDLGISNVRLLTNNP 231
+GI L K + YN A+ V P R++ IG IL DLG+ ++++TNNP
Sbjct: 358 KGIDLSHKPRTYNTNSDQAEGVS------FPVASREYGIGAQILRDLGVREMKVMTNNP 410
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,321,405
Number of Sequences: 60738
Number of extensions: 869223
Number of successful extensions: 1719
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1701
Number of HSP's gapped (non-prelim): 5
length of query: 304
length of database: 30,389,216
effective HSP length: 106
effective length of query: 198
effective length of database: 23,950,988
effective search space: 4742295624
effective search space used: 4742295624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)