ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3182 check: MH C KOG2456 Energy production and conversion Aldehyde dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3182 1094239 1095801 521
(521 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR110c [C] KOG2456 Aldehyde dehydrogenase 525 e-149
CE27441 [C] KOG2456 Aldehyde dehydrogenase 278 2e-74
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 276 7e-74
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 274 2e-73
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 273 5e-73
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 265 1e-70
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 265 1e-70
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 259 9e-69
CE13415 [C] KOG2456 Aldehyde dehydrogenase 254 2e-67
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 233 5e-61
7304212 [C] KOG2456 Aldehyde dehydrogenase 219 8e-57
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 203 6e-52
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 172 1e-42
7297513 [C] KOG2450 Aldehyde dehydrogenase 156 6e-38
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 144 4e-34
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 143 5e-34
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 142 1e-33
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 142 2e-33
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 141 2e-33
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 138 2e-32
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 135 1e-31
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 135 1e-31
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 131 2e-30
7301355 [C] KOG2451 Aldehyde dehydrogenase 130 6e-30
CE23852 [C] KOG2450 Aldehyde dehydrogenase 128 2e-29
YMR169c [C] KOG2450 Aldehyde dehydrogenase 128 2e-29
YER073w [C] KOG2450 Aldehyde dehydrogenase 128 2e-29
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 125 2e-28
YMR170c [C] KOG2450 Aldehyde dehydrogenase 124 3e-28
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 124 3e-28
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 124 3e-28
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 123 8e-28
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 122 1e-27
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 119 8e-27
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 119 1e-26
CE29393 [C] KOG2450 Aldehyde dehydrogenase 119 1e-26
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 119 1e-26
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 117 4e-26
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 117 5e-26
YOR374w [C] KOG2450 Aldehyde dehydrogenase 115 2e-25
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 115 2e-25
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 114 3e-25
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 113 6e-25
CE07233 [C] KOG2450 Aldehyde dehydrogenase 112 1e-24
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 112 1e-24
CE10542 [C] KOG2451 Aldehyde dehydrogenase 112 2e-24
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 110 5e-24
YBR006w [C] KOG2451 Aldehyde dehydrogenase 110 7e-24
7301524 [C] KOG2450 Aldehyde dehydrogenase 109 9e-24
CE06980 [C] KOG2450 Aldehyde dehydrogenase 108 1e-23
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 108 3e-23
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 106 7e-23
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 106 7e-23
CE24573 [C] KOG2450 Aldehyde dehydrogenase 106 7e-23
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 105 2e-22
CE01232 [C] KOG2453 Aldehyde dehydrogenase 104 4e-22
YPL061w [C] KOG2450 Aldehyde dehydrogenase 103 6e-22
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 97 6e-20
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 89 2e-17
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 88 3e-17
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 87 5e-17
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 87 5e-17
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 84 4e-16
7293810 [C] KOG2453 Aldehyde dehydrogenase 83 9e-16
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 83 1e-15
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 77 5e-14
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 75 2e-13
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 70 1e-11
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 70 1e-11
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 69 1e-11
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 62 3e-09
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 61 4e-09
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 56 2e-07
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 525 bits (1353), Expect = e-149
Identities = 262/513 (51%), Positives = 356/513 (69%), Gaps = 6/513 (1%)
Query: 6 FTDLKSIPGKIELAKQFYRSRQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAA 65
+T + I +E+++ F+ +Q +L+ +PR D+ R L+KLY+AVKD+EE LI A
Sbjct: 11 YTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKKDLEFRQLQLKKLYYAVKDHEEELIDA 70
Query: 66 ASKDFHRARSETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALG 125
KDFHR + E++ E L N+IL+LI+ + K I+P+++ S FG T VEKI+ G
Sbjct: 71 MYKDFHRNKIESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRG 130
Query: 126 TVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVET 184
+VL+I+PFNFP+LLA PLA A+A GN++V KPSELTP A VME + A F G ++
Sbjct: 131 SVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQV 190
Query: 185 VQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLP 244
VQG +ET+ L++ GKFD IFYTGS VG+I+AEKAAKSLTPCVLELGGKSP FI+ N
Sbjct: 191 VQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFK 250
Query: 245 KSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSVTSDTEY 304
S + A++RI++ + GN+GQICV+ DY+L SIY + + C+ VLNEFYPS T++
Sbjct: 251 ASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYPSFDEQTDF 310
Query: 305 THMIHERAYNRIQTVIETTKGQKTVAQ----HSDNLPPLCIPPTIISDVSWDDPSMTGEN 360
T MIHE AY + I +T G K V +SD +PPTI+ ++ WDDP M EN
Sbjct: 311 TRMIHEPAYKKAVASINSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDPLMKQEN 370
Query: 361 FGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLH 420
F P+LPI+ Y DLDETI+ +I+ DTPLVQYIF++S+ EI+ ILTR+RSG CVV DT++H
Sbjct: 371 FAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIH 430
Query: 421 VGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIFKQPFWVDLLIYVRYPPFDKLNTRIS 480
VGI +APFGGIGTSGYGNY G Y F TF+HERTIFKQP+W D +++RYPP ++
Sbjct: 431 VGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQPYWNDFTLFMRYPPNSAQKEKLV 490
Query: 481 QISLEDKPNFDRNGRRIYGIKNIGIILTSGVLL 513
+ ++E KP FDRNG +G++ L++ V+L
Sbjct: 491 RFAMERKPWFDRNGNNKWGLRQY-FSLSAAVIL 522
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 278 bits (710), Expect = 2e-74
Identities = 160/460 (34%), Positives = 250/460 (53%), Gaps = 19/460 (4%)
Query: 16 IELAKQFYRSRQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARS 75
+E ++++R+ + + + R + L KL +++N E L A KD R
Sbjct: 7 VETQRKYFRTGETK----------PVKFRKQQLLKLKKFIEENREALSEAVWKDLRRRHE 56
Query: 76 ETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNF 135
T +E+ I Y +KN+ ++P ++ + +EK G VL+ISP+N+
Sbjct: 57 STEILEIGMTIQEIDYFLKNIDDWVKPTHVEKTFTTA-LDKPVIEKDPKGVVLIISPWNY 115
Query: 136 PILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSAL 195
P+ + L P+ AIA GN+VV KPSEL+ A E++ + FE V V GG ET+ L
Sbjct: 116 PVSMILLPMVPAIAAGNTVVIKPSELSENVAATFEKLIPKYFESKYVTVVNGGIPETTDL 175
Query: 196 VESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRI 255
++ +FD I YTG V II AAK LTP LELGGK PV + + + + + +RI
Sbjct: 176 LKE-RFDHILYTGCPPVAKIIMTAAAKHLTPVTLELGGKCPVVVEDD---ADIDISAKRI 231
Query: 256 YYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYN 314
+ N GQ C+A DY+L ++ + V + +K +NEFY V + +Y MI++R ++
Sbjct: 232 AWGKWLNCGQTCLAPDYILVNSTVKPKLVAAIRKYVNEFYGEDVKASKDYARMINQRHFD 291
Query: 315 RIQTVIETTKGQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLD 374
RI +++ T+G + D L IPPT++ DV DP M E FGP+LPI+
Sbjct: 292 RISGLLDKTQGAVLIGGERDRAD-LYIPPTVL-DVEKSDPFMHDEIFGPVLPIITVQSFS 349
Query: 375 ETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTS 434
E+++ I + PL YIFT ++ ++ +L SG VND L+H+ ++ PFGG+G S
Sbjct: 350 ESLE-YIADGEKPLAAYIFTRNEAKVKRLLNETSSGGVTVNDVLMHITVDTLPFGGVGVS 408
Query: 435 GYGNYHGPYTFKTFTHERTIFKQPFWVDLLIYVRYPPFDK 474
G G Y G Y F TFTHE+++ + F+ + L+ RYPP +
Sbjct: 409 GMGRYRGKYGFDTFTHEKSVLHRGFFGESLLAARYPPLSQ 448
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 276 bits (705), Expect = 7e-74
Identities = 162/447 (36%), Positives = 243/447 (54%), Gaps = 11/447 (2%)
Query: 26 RQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPL 85
++AR A S S R + RI+ L+ L +++ E+ L+ A + D H+ E+V +
Sbjct: 9 KRARAAFS-SGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYV 67
Query: 86 YNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLA 145
I Y+I+ + + + ++ + ++ LG VLVI +N+P L + P+
Sbjct: 68 LEEIEYMIQKLPEWAADEPVEKTPQTQQ-DELYIHSEPLGVVLVIGTWNYPFNLTIQPMV 126
Query: 146 GAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDKIF 205
GAIA GN+VV KPSEL+ A ++ I + +K + GG ET+ L++ +FD I
Sbjct: 127 GAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKE-RFDHIL 185
Query: 206 YTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQ 265
YTGST VG II AAK LTP LELGGKSP ++ N + A RRI + N+GQ
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC---DLDVACRRIAWGKFMNSGQ 242
Query: 266 ICVAADYVLCPDSIYDEFVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYNRIQTVIETTK 324
CVA DY+LC SI ++ V+ KK L EFY +Y +I R + R+ +IE
Sbjct: 243 TCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIE--- 299
Query: 325 GQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRF 384
GQK + + I PTI++DV P M E FGP+LPI+ L+E I + +R
Sbjct: 300 GQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQR- 358
Query: 385 DTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYT 444
+ PL Y+F+++ I ++ SG ND ++H+ + PFGG+G SG G+YHG +
Sbjct: 359 EKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKS 418
Query: 445 FKTFTHERTIFKQPFWVDLLIYVRYPP 471
F+TF+H R+ +P D + VRYPP
Sbjct: 419 FETFSHRRSCLVRPLMNDEGLKVRYPP 445
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 274 bits (701), Expect = 2e-73
Identities = 161/447 (36%), Positives = 242/447 (54%), Gaps = 11/447 (2%)
Query: 26 RQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPL 85
++AR A S S R + R + L+ L +++ E+ L+ A + D H+ E+V +
Sbjct: 9 KRARAAFS-SGRTRPLQFRFQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYV 67
Query: 86 YNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLA 145
I Y+I+ + + + ++ + ++ LG VLVI +N+P L + P+
Sbjct: 68 LEEIEYMIQKLPEWAADEPVEKTPQTQQ-DELYIHSEPLGVVLVIGTWNYPFNLTIQPMV 126
Query: 146 GAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDKIF 205
GAIA GN+VV KPSEL+ A ++ I + +K + GG ET+ L++ +FD I
Sbjct: 127 GAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKE-RFDHIL 185
Query: 206 YTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQ 265
YTGST VG II AAK LTP LELGGKSP ++ N + A RRI + N+GQ
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNC---DLDVACRRIAWGKFMNSGQ 242
Query: 266 ICVAADYVLCPDSIYDEFVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYNRIQTVIETTK 324
CVA DY+LC SI ++ V+ KK L EFY +Y +I R + R+ +IE
Sbjct: 243 TCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIE--- 299
Query: 325 GQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRF 384
GQK + + I PTI++DV P M E FGP+LPI+ L+E I + +R
Sbjct: 300 GQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQR- 358
Query: 385 DTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYT 444
+ PL Y+F+++ I ++ SG ND ++H+ + PFGG+G SG G+YHG +
Sbjct: 359 EKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKS 418
Query: 445 FKTFTHERTIFKQPFWVDLLIYVRYPP 471
F+TF+H R+ +P D + VRYPP
Sbjct: 419 FETFSHRRSCLVRPLMNDEGLKVRYPP 445
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 273 bits (698), Expect = 5e-73
Identities = 162/451 (35%), Positives = 251/451 (54%), Gaps = 12/451 (2%)
Query: 44 RIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIKNMKKEIEPK 103
R+ L+KL ++E ++AA D + E+ E+ L N+I +K +K + P+
Sbjct: 34 RVTQLKKLMIICDNHEPEIVAALRDDLGKPELESSVYEVSLLRNSIKLALKQLKNWMAPE 93
Query: 104 KIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTP 163
K K SL V + LG VLVIS +N+P LL++DP+ GAI+ GN+VV KPSEL P
Sbjct: 94 KAKTSLTTFPASAEIVSE-PLGVVLVISAWNYPFLLSIDPVIGAISAGNAVVLKPSELAP 152
Query: 164 ACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS 223
A + ++ ++ + + V V+G ETSAL+E K+DKIFYTGS+ +G +I AAK
Sbjct: 153 ASSALLTKLLEQYLDPSAVRVVEGAVTETSALLEQ-KWDKIFYTGSSKIGRVIMAAAAKH 211
Query: 224 LTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMG-NAGQICVAADYVLCPDSIYDE 282
LTP VLELGGKSPV + + + + +RRI G N GQ CV+ DY+L +
Sbjct: 212 LTPVVLELGGKSPVVVDSD---TDLKVTVRRIIVGKWGCNNGQACVSPDYILTTKEYAPK 268
Query: 283 FVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYNRIQTVI-ETTKGQKTVAQHSDNLPPLC 340
+D+ K L +FY + + + +++ ++R+ ++ E K V + L
Sbjct: 269 LIDAMKLELEKFYGKNPIESKDMSRIVNSNHFDRLSKLLDEKEVSDKIVYGGEKDRENLK 328
Query: 341 IPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEI 400
I PTI+ DV D M+ E FGP+LPI+ +L+E+ D + R PL Y+FT++K
Sbjct: 329 IAPTILLDVPLDSLIMSEEIFGPLLPILTLNNLEESFDVIRSR-PKPLAAYLFTHNKKLK 387
Query: 401 DHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIFKQPFW 460
+ + +G VVND +H+ + PFGG+G SG G YHG ++F F+H++ + + +
Sbjct: 388 ERFAATVSAGGIVVNDIAVHLALHTLPFGGVGESGMGAYHGKFSFDAFSHKKAVLYRSLF 447
Query: 461 VDLLIYVRYPPFDKLNTRISQISLEDKPNFD 491
D VRYPP+ + R+ + +L D FD
Sbjct: 448 GDSA--VRYPPYSRGKLRLLK-ALVDSNIFD 475
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 265 bits (677), Expect = 1e-70
Identities = 151/449 (33%), Positives = 253/449 (55%), Gaps = 14/449 (3%)
Query: 24 RSRQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELV 83
R RQA L S R+ + R++ L+ L V++ E+ ++ A + D ++ + E++
Sbjct: 7 RVRQAFL----SGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVI 62
Query: 84 PLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDP 143
+ I ++++N+ + + K +K ++L +++ LG VL+I +N+P +L + P
Sbjct: 63 TVLGEIDFMLENLPEWVTAKPVKKNVLT-MLDEAYIQPQPLGVVLIIGAWNYPFVLTIQP 121
Query: 144 LAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDK 203
L GAIA GN+V+ KPSEL+ A+++ ++ + ++ + GG EET+ L++ +FD
Sbjct: 122 LIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQ-RFDH 180
Query: 204 IFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNA 263
IFYTG+T VG I+ E AAK LTP LELGGKSP +I + + RRI + N
Sbjct: 181 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKD---CDLDIVCRRITWGKYMNC 237
Query: 264 GQICVAADYVLCPDSIYDEFVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYNRIQTVIET 322
GQ C+A DY+LC S+ ++ V K+ + EFY ++ +Y +I+ R + RI +++E
Sbjct: 238 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLE- 296
Query: 323 TKGQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIK 382
GQK + I PT+++DV M E FGPILPI+ ++DE I+ + +
Sbjct: 297 --GQKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINE 354
Query: 383 RFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGP 442
R + PL Y+F+++ I ++ SG ND ++H + PFGG+G+SG G YHG
Sbjct: 355 R-EKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGK 413
Query: 443 YTFKTFTHERTIFKQPFWVDLLIYVRYPP 471
++F TF+H+R + + +RYPP
Sbjct: 414 HSFDTFSHQRPCLLKSLKREGANKLRYPP 442
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 265 bits (677), Expect = 1e-70
Identities = 151/449 (33%), Positives = 253/449 (55%), Gaps = 14/449 (3%)
Query: 24 RSRQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELV 83
R RQA L S R+ + R++ L+ L V++ E+ ++ A + D ++ + E++
Sbjct: 7 RVRQAFL----SGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVI 62
Query: 84 PLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDP 143
+ I ++++N+ + + K +K ++L +++ LG VL+I +N+P +L + P
Sbjct: 63 TVLGEIDFMLENLPEWVTAKPVKKNVLT-MLDEAYIQPQPLGVVLIIGAWNYPFVLTIQP 121
Query: 144 LAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDK 203
L GAIA GN+V+ KPSEL+ A+++ ++ + ++ + GG EET+ L++ +FD
Sbjct: 122 LIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQ-RFDH 180
Query: 204 IFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNA 263
IFYTG+T VG I+ E AAK LTP LELGGKSP +I + + RRI + N
Sbjct: 181 IFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKD---CDLDIVCRRITWGKYMNC 237
Query: 264 GQICVAADYVLCPDSIYDEFVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYNRIQTVIET 322
GQ C+A DY+LC S+ ++ V K+ + EFY ++ +Y +I+ R + RI +++E
Sbjct: 238 GQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLE- 296
Query: 323 TKGQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIK 382
GQK + I PT+++DV M E FGPILPI+ ++DE I+ + +
Sbjct: 297 --GQKIAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINE 354
Query: 383 RFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGP 442
R + PL Y+F+++ I ++ SG ND ++H + PFGG+G+SG G YHG
Sbjct: 355 R-EKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGK 413
Query: 443 YTFKTFTHERTIFKQPFWVDLLIYVRYPP 471
++F TF+H+R + + +RYPP
Sbjct: 414 HSFDTFSHQRPCLLKSLKREGANKLRYPP 442
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 259 bits (661), Expect = 9e-69
Identities = 149/443 (33%), Positives = 241/443 (53%), Gaps = 10/443 (2%)
Query: 44 RIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIKNMKKEIEPK 103
R LQ L +++N++ L A ++D H++ E+ E+ + ++N++ ++ +
Sbjct: 26 RAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAWMKDE 85
Query: 104 KIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTP 163
++ +L A + F+ K G VL+I+P+N+P+ L L PL GA+A GN VV KPSE++
Sbjct: 86 RVPKNL-ATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISK 144
Query: 164 ACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS 223
+++ E+ + ++ V GG +ET L+E +FD IF+TGS VG I+ AAK
Sbjct: 145 NVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEH-RFDYIFFTGSPRVGKIVMTAAAKH 203
Query: 224 LTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEF 283
LTP LELGGK+P ++ N +T R+ + NAGQ CVA DYVLC + +
Sbjct: 204 LTPVTLELGGKNPCYVDDNCDP---QTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERL 260
Query: 284 VDSCKKVLNEFY-PSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPPLCIP 342
+ + + + FY S +I+++ + R++ ++ G+ + SD I
Sbjct: 261 LPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGC--GRVAIGGQSDESDRY-IA 317
Query: 343 PTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDH 402
PT++ DV +P M E FGPILPI+ LDE I+ I R + PL Y F+NS +
Sbjct: 318 PTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIE-FINRREKPLALYAFSNSSQVVKR 376
Query: 403 ILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIFKQPFWVD 462
+LT+ SG ND +H+ + PFGG+G SG G YHG ++F TF+H R + ++
Sbjct: 377 VLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSPGME 436
Query: 463 LLIYVRYPPFDKLNTRISQISLE 485
L +RYPP R+ +++E
Sbjct: 437 KLNALRYPPQSPRRLRMLLVAME 459
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 254 bits (650), Expect = 2e-67
Identities = 150/419 (35%), Positives = 232/419 (54%), Gaps = 11/419 (2%)
Query: 43 ERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIKNMKKEIEP 102
E++ L+KL +++N L KD R T +EL I Y +KN+ ++P
Sbjct: 27 EQLLQLKKL---IEENRAALTEVVWKDLRRRHEVTEPMELGGSLEEIAYYLKNLDDWMKP 83
Query: 103 KKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELT 162
++ ++ ++ K G VLVISP+N+P+ + L P+ +IA GN++V KPSEL+
Sbjct: 84 TYVEPTVATLPTDKPYIVKDPKGVVLVISPWNYPVSMVLLPMIPSIAAGNTIVIKPSELS 143
Query: 163 PACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAK 222
A + E++ + F+ V V GG ET+ L++ +FD I YTG V II AAK
Sbjct: 144 ENTAILFEKLIPKYFDPKYVTIVNGGIPETTELLKE-RFDHIIYTGCPPVAKIIMAAAAK 202
Query: 223 SLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDE 282
LTP LELGGK PV + + + E + +RI N GQ C+A DY+L + +
Sbjct: 203 HLTPVTLELGGKCPVVVEDD---ADIEISAQRIARGKWLNCGQTCLAPDYILVSSATKPK 259
Query: 283 FVDSCKKVLNEFYPSVTSDT-EYTHMIHERAYNRIQTVIETTKGQKTVA-QHSDNLPPLC 340
FV + +K L EFY ++ +Y+ +I++R ++RI +++ +KG + S +
Sbjct: 260 FVAAIQKCLKEFYGGNAKESKDYSRVINQRHFDRISALLDESKGVVLAGNEESRDRSDRF 319
Query: 341 IPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEI 400
IPPT++ DV DP M E FGP+LPI+ +L E+ID I + + PL YIFT + ++
Sbjct: 320 IPPTVL-DVEKTDPFMHDEIFGPVLPIITVKNLCESID-FINKGEKPLAAYIFTKDEAKV 377
Query: 401 DHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIFKQPF 459
L SG VND ++HV + PFGG+G SG G Y G + F TFTHE+++ ++ F
Sbjct: 378 QRFLNETTSGGVTVNDVIMHVAVITLPFGGVGVSGMGRYRGKFGFDTFTHEKSVLQRVF 436
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 233 bits (594), Expect = 5e-61
Identities = 131/365 (35%), Positives = 199/365 (53%), Gaps = 9/365 (2%)
Query: 116 TTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNE 175
+ F+ K G VL+I+P+N+P+ L L L G + GN VV KPSE++ +V+ E+ +
Sbjct: 16 SVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQ 75
Query: 176 AFEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
++ V GG +ET L+E K D IF+TGS VG I+ A K LTP LELGGK+
Sbjct: 76 YLDQSCFAVVLGGPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKN 134
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFY 295
P ++ N +T R+ + NAGQ CVA DYVLC + + + + + + FY
Sbjct: 135 PCYVDDNCDP---QTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY 191
Query: 296 -PSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPPLCIPPTIISDVSWDDP 354
S +I+++ + R++ ++ G+ + S N I PT++ DV +P
Sbjct: 192 GDDPQSSPNLGRIINQKQFQRLRALLGC--GRVAIGGQS-NESDRYIAPTVLVDVQETEP 248
Query: 355 SMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVV 414
M E FGPILPI+ +DE I I R + PL Y F+NS+ ++ +L R SG+
Sbjct: 249 VMQEEIFGPILPIVNVQSVDEAIK-FINRQEKPLALYAFSNSRQVVNQMLERTSSGSFGG 307
Query: 415 NDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIFKQPFWVDLLIYVRYPPFDK 474
N+ ++ + PFGG+G SG G YHG +TF TF+H RT P ++ L +RYPP+
Sbjct: 308 NEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIRYPPYTD 367
Query: 475 LNTRI 479
N ++
Sbjct: 368 WNQQL 372
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 219 bits (558), Expect = 8e-57
Identities = 143/441 (32%), Positives = 229/441 (51%), Gaps = 19/441 (4%)
Query: 26 RQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPL 85
++ARLA S S + +++ R + L+ L +++E +I+A D R + E+L +E +
Sbjct: 9 QRARLAFS-SGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFM 67
Query: 86 YNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLA 145
N+I +++ + + ++ +K S + + + G VLVI +N+P+ L L P+A
Sbjct: 68 KNDIRHILFQLDEWVQSEKPPKSFV-NMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVA 126
Query: 146 GAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDKIF 205
AIA GN VV KPSE+ CA+ + ++ + + V GG ET+ L+ +FD IF
Sbjct: 127 SAIAAGNCVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELLNQ-RFDYIF 185
Query: 206 YTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQ 265
YTGST VG II A K LTP LELGGKSP +I ++ TA++RI + + N GQ
Sbjct: 186 YTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDKSV---DMRTAVKRILWGKLINCGQ 242
Query: 266 ICVAADYVLCPDSIYDEFVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYNRIQTVIETTK 324
C+A DY+LC + ++F+ K VL E+Y ++ S + + +I+ N Q ++ K
Sbjct: 243 TCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINA---NNFQRLLGLMK 299
Query: 325 GQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRF 384
+ + + I PTI+ DV DP M E FGPILPI + I + R
Sbjct: 300 SGRVAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINAR- 358
Query: 385 DTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLH--------VGIEEAPFGGIGTSGY 436
++PLV YIFT + + + + +SG VNDT++H V + AP + Y
Sbjct: 359 ESPLVLYIFTPTAEVQNLFINGTQSGGLCVNDTIMHYAGKNPTSVNPKVAPIEMLMAVDY 418
Query: 437 GNYHGPYTFKTFTHERTIFKQ 457
N P F++ + K+
Sbjct: 419 DNKEKPLVIYVFSNSNKLVKE 439
Score = 77.8 bits (190), Expect = 4e-14
Identities = 48/153 (31%), Positives = 77/153 (49%), Gaps = 13/153 (8%)
Query: 339 LCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKD 398
LC+ TI+ + +P+ PI +M D D + PLV Y+F+NS
Sbjct: 386 LCVNDTIMH-YAGKNPTSVNPKVAPIEMLMA-VDYDNK--------EKPLVIYVFSNSNK 435
Query: 399 EIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIFKQP 458
+ SG N+T++H G++ PFGG+G SG G YHG Y F+TFTH+++ +
Sbjct: 436 LVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKD 495
Query: 459 F--WVDLLIYVRYPPF-DKLNTRISQISLEDKP 488
+ L RYPP+ D+ + +S + + +P
Sbjct: 496 LSPLGEKLSSARYPPYSDRKGSLLSFLLRKRRP 528
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 203 bits (516), Expect = 6e-52
Identities = 136/453 (30%), Positives = 213/453 (46%), Gaps = 55/453 (12%)
Query: 35 SPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIK 94
S R + R + +Y VKDNE+++ A +D + +E EL + I
Sbjct: 21 SGRTRSLKWRKAQIGAIYEMVKDNEDKICNALFQDLGKHSTEAFRDELGVVLRTATVAIN 80
Query: 95 NMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSV 154
+ K PK K+ LL + + + GTVLV+S +NFPI L+LDPL GAIA GN+V
Sbjct: 81 CLDKWAVPKHSKLPLLFYPAKGKVISE-PYGTVLVLSSWNFPISLSLDPLIGAIAAGNTV 139
Query: 155 VFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGT 214
+ K SEL+P + + + + ++ ++GG + + L++ ++DKIF+TGS +G
Sbjct: 140 LLKSSELSPNASAFLAKTIPAYLDTKAIKVIEGGPDVATILLQH-QWDKIFFTGSPKIGR 198
Query: 215 IIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVL 274
II AA+ LTP LELGGKS C++ DYVL
Sbjct: 199 IIMAAAAQHLTPVTLELGGKS-------------------------------CISVDYVL 227
Query: 275 CPDSIYDEFVDSCKKVLNEFYPSVTSDTE-YTHMIHERAYNRIQTVIETTKGQKTVAQHS 333
S +D K + F+ ++ + + ++ R+ ++ +
Sbjct: 228 IEKSFAPTLIDMLKPTIKSFFGENPKESGCLSRIANKHHVQRLSRLLSDPR--------- 278
Query: 334 DNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIF 393
PTI+ D D M E FGPILPI+ D+ E+I +I PL Y F
Sbjct: 279 ---------PTILLDPPLDSEIMNEEIFGPILPIITVRDIQESIG-IINTKPKPLAIYAF 328
Query: 394 TNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERT 453
TN ++ IL+ SG+ ND ++ + PFGG+G SG G YHG Y+F F+HE+
Sbjct: 329 TNDENLKTRILSETSSGSVTFNDVMIQYMCDALPFGGVGESGIGRYHGKYSFDCFSHEKA 388
Query: 454 IFKQPFWVDLLIYVRYPPFDKLNTRISQISLED 486
I + +DL RYPP++ +++ +
Sbjct: 389 IMEGSLGMDL--EARYPPWNNFKLTFIRLAFRE 419
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 172 bits (435), Expect = 1e-42
Identities = 104/339 (30%), Positives = 180/339 (52%), Gaps = 26/339 (7%)
Query: 138 LLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVETVQGGAEETSALVE 197
+L+++P+ GAIA GN+VV KPSE+ PA + ++ ++ +E + + ++GG ET+AL++
Sbjct: 187 VLSVEPVIGAIAAGNAVVLKPSEIAPAASSLLAKLFSEYLDNTTIRVIEGGVPETTALLD 246
Query: 198 SGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQW-ETAIRRIY 256
K+DKIF+T + ++ K K F S L W + A RRI
Sbjct: 247 Q-KWDKIFFTD---LSLLLKHKIVK---------------FRSHTLIVVLWLKVAARRII 287
Query: 257 YSSMG-NAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFY-PSVTSDTEYTHMIHERAYN 314
N+GQ C+ DYV+ + +D+ K L F+ + + + +++ +
Sbjct: 288 AGKWACNSGQACIGVDYVITTKDFASKLIDALKTELETFFGQNALESKDLSRIVNSFHFK 347
Query: 315 RIQTVI-ETTKGQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDL 373
R+++++ E K V L I PTI+ DV M E FGP+LPI+ +
Sbjct: 348 RLESMLKENGVANKIVHGGRITEDKLKISPTILLDVPEASSMMQEEIFGPLLPIITVQKI 407
Query: 374 DETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGT 433
++ +I+ PL Y+FTN+K+ + + +G +NDT+LHV +++ PFGG+G
Sbjct: 408 EDGFQ-VIRSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGVGE 466
Query: 434 SGYGNYHGPYTFKTFTHERTIFKQPFWVDLLIYVRYPPF 472
SG G YHG ++++TF+H++ + + F D +RYPP+
Sbjct: 467 SGIGAYHGKFSYETFSHKKGVLYRSFSGD--ADLRYPPY 503
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 156 bits (395), Expect = 6e-38
Identities = 132/434 (30%), Positives = 203/434 (46%), Gaps = 35/434 (8%)
Query: 37 RATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLI--- 93
R D +ER R L +L ++ ++ L + + D + S + ++L N+ Y
Sbjct: 97 RRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWA 156
Query: 94 -KNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGN 152
KN K I + +F T+ +G I P+NFPIL+ L A+A GN
Sbjct: 157 DKNHGKTIP-------MDGDFF--TYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGN 207
Query: 153 SVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQGGAEETSALVESGKFDKIFYTGSTT 211
++V KP+E T A + ++ EA F +G V V G +AL DK+ +TGST
Sbjct: 208 TIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTD 267
Query: 212 VGTIIAEKAAK-SLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAA 270
VG +I + +L LELGGKSP I L + + A+ ++ N GQ C A
Sbjct: 268 VGKLIQLASGNTNLKRVTLELGGKSPNII---LSDTDMDYAVETAHFGLFFNMGQCCCAG 324
Query: 271 DYVLCPDSIYDEFVDSC------KKVLNEFYPSVTSDTEYTHMIHERAYNRIQTVIETTK 324
D IYDEFV+ + V N F +TE ++E +I +I+T K
Sbjct: 325 SRTFVEDKIYDEFVERSAERAKKRTVGNPF----DLNTEQGPQVNEEQMEKILGMIKTGK 380
Query: 325 --GQKTVAQHS--DNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTL 380
G K VA S + LP + PT+ +DV D E FGP+ ++R+ LDE I+
Sbjct: 381 KQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIER- 439
Query: 381 IKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYH 440
+ L +FT D+ ++I+ +R+G VN +V +APFGG SG+G +
Sbjct: 440 ANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVN--TYNVLAAQAPFGGYKMSGHGREN 497
Query: 441 GPYTFKTFTHERTI 454
G Y +T +++
Sbjct: 498 GEYALSNYTEVKSV 511
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 144 bits (362), Expect = 4e-34
Identities = 137/455 (30%), Positives = 211/455 (46%), Gaps = 34/455 (7%)
Query: 15 KIELAKQFYRSRQARLAQSKSP-RATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRA 73
K ++ K +RQA Q SP R D +ER R L KL ++ + L S + +
Sbjct: 57 KEDVDKAVKAARQA--FQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKL 114
Query: 74 RSETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPF 133
S +L + Y +I+ + I + ++F T+ +G I P+
Sbjct: 115 YSNAYLSDLAGCIKTLRYCA-GWADKIQGRTIPID--GNFF--TYTRHEPIGVCGQIIPW 169
Query: 134 NFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQGGAEET 192
NFP+++ + + A++ GN+VV KP+E TP A + + EA F G V V G
Sbjct: 170 NFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTA 229
Query: 193 SALVESG-KFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFISPNLPKSQWET 250
A + S DK+ +TGST VG +I E A KS L LELGGKSP + L + +
Sbjct: 230 GAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIV---LADADLDN 286
Query: 251 AIRRIYYSSMGNAGQICVAADYVLCPDSIYDEF----VDSCKKVL--NEFYPSVTSDTEY 304
A+ ++ + GQ C+AA + +SIYDEF V+ KK + N P VT +
Sbjct: 287 AVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQ- 345
Query: 305 THMIHERAYNRIQTVIETTKGQKTVAQHSDNLPP-----LCIPPTIISDVSWDDPSMTGE 359
I + Y++I +IE+ G+K A+ P + PT+ S+V+ + E
Sbjct: 346 ---IDKEQYDKILDLIES--GKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEE 400
Query: 360 NFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLL 419
FGP+ IM++ LD+ I F L +FT D+ I + +++G VN
Sbjct: 401 IFGPVQQIMKFKSLDDVIKRANNTF-YGLSAGVFTKDIDKAITISSALQAGTVWVN--CY 457
Query: 420 HVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
V + PFGG SG G G Y F +T +T+
Sbjct: 458 GVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTV 492
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 143 bits (361), Expect = 5e-34
Identities = 137/455 (30%), Positives = 211/455 (46%), Gaps = 34/455 (7%)
Query: 15 KIELAKQFYRSRQARLAQSKSP-RATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRA 73
K ++ K +RQA Q SP R D +ER R L KL ++ + L S + +
Sbjct: 57 KEDVDKAVKAARQA--FQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKL 114
Query: 74 RSETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPF 133
S +L + Y +I+ + I + ++F T+ +G I P+
Sbjct: 115 YSNAYLNDLAGCIKTLRYCA-GWADKIQGRTIPID--GNFF--TYTRHEPIGVCGQIIPW 169
Query: 134 NFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQGGAEET 192
NFP+++ + + A++ GN+VV KP+E TP A + + EA F G V V G
Sbjct: 170 NFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTA 229
Query: 193 SALVESG-KFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFISPNLPKSQWET 250
A + S DK+ +TGST VG +I E A KS L LELGGKSP + L + +
Sbjct: 230 GAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIV---LADADLDN 286
Query: 251 AIRRIYYSSMGNAGQICVAADYVLCPDSIYDEF----VDSCKKVL--NEFYPSVTSDTEY 304
A+ ++ + GQ C+AA + +SIYDEF V+ KK + N P VT +
Sbjct: 287 AVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQ- 345
Query: 305 THMIHERAYNRIQTVIETTKGQKTVAQHSDNLPP-----LCIPPTIISDVSWDDPSMTGE 359
I + Y++I +IE+ G+K A+ P + PT+ S+V+ + E
Sbjct: 346 ---IDKEQYDKILDLIES--GKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEE 400
Query: 360 NFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLL 419
FGP+ IM++ LD+ I F L +FT D+ I + +++G VN
Sbjct: 401 IFGPVQQIMKFKSLDDVIKRANNTF-YGLSAGVFTKDIDKAITISSALQAGTVWVN--CY 457
Query: 420 HVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
V + PFGG SG G G Y F +T +T+
Sbjct: 458 GVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTV 492
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 142 bits (358), Expect = 1e-33
Identities = 75/206 (36%), Positives = 118/206 (56%), Gaps = 5/206 (2%)
Query: 116 TTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNE 175
+ F+ K G VL+I+P+N+P+ L L PL GA+A GN VV KPSE++ +++ E+ +
Sbjct: 60 SAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQ 119
Query: 176 AFEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
++ V GG +ET L+E +FD IF+TGS VG I+ AAK LTP LELGGK+
Sbjct: 120 YVDQSCFAVVLGGPQETGQLLEH-RFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKN 178
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFY 295
P ++ N +T R+ + NAGQ CVA DYVLC + + + + + + FY
Sbjct: 179 PCYVDDNCDP---QTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY 235
Query: 296 -PSVTSDTEYTHMIHERAYNRIQTVI 320
S +I+++ + R++ ++
Sbjct: 236 GDDPQSSPNLGRIINQKQFQRLRALL 261
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 142 bits (357), Expect = 2e-33
Identities = 109/338 (32%), Positives = 165/338 (48%), Gaps = 25/338 (7%)
Query: 119 VEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-F 177
V K +G V I+P+NFP+ + + A+A G +VV KPSELTP A E+ +A
Sbjct: 184 VLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAAAELALQAGV 243
Query: 178 EKGQVETVQGGAEET-SALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSP 236
G + V G A E AL+ S + KI +TGST VG + AA ++ LELGG +P
Sbjct: 244 PPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTVKKVSLELGGNAP 303
Query: 237 VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLN--EF 294
+ + + A++ + N+GQ CV A+ VL D IYD+F ++ + + E
Sbjct: 304 SIV---FDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSEAVQKLEV 360
Query: 295 YPSVTSDTEYTHMIHERAYNRIQTVIE--TTKGQKTV---AQHSDNLPPLCIPPTIISDV 349
T +I++ A +++T ++ +KG K + +HS L PT+I DV
Sbjct: 361 GDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHS--LGMTFYEPTVIRDV 418
Query: 350 SWDDPSMTGENFGPILPIMRYTDLDETI----DTLIKRFDTPLVQYIFTNSKDEIDHILT 405
S + E FGP+ P++R+ ++ I DT+ L YIFTNS +
Sbjct: 419 SDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTI-----AGLAAYIFTNSVQRSWRVFE 473
Query: 406 RIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPY 443
+ G VN+ L + E APFGG+ SG G Y
Sbjct: 474 ALEYGLVGVNEGL--ISTEVAPFGGVKQSGLGREGSKY 509
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 141 bits (356), Expect = 2e-33
Identities = 104/346 (30%), Positives = 164/346 (47%), Gaps = 15/346 (4%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA- 176
+ ++ +G I P+N+P+ +A +A A+A GN ++ K +E TP + EA
Sbjct: 149 YAKRTPIGVCGQIVPWNYPLNMAGWKIAPALAAGNCIIIKSAETTPLSLLYFATLVEEAG 208
Query: 177 FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
F KG V + G G S + + DKI +TGST VG I+ + AA +L LE GGKS
Sbjct: 209 FPKGVVNIISGLGTVAGSYMAKHPGIDKIAFTGSTKVGVIVQQLAASNLKAVTLECGGKS 268
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKK-VLNEF 294
P + + Q A++ M N+GQIC + + DS+YD+F++ KK V+ ++
Sbjct: 269 PFLVFEDADLDQ---AVKWAALGIMYNSGQICTSNSRIYVQDSVYDKFIELFKKHVIQDY 325
Query: 295 YPSVTSD--TEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPPL----CIPPTIISD 348
+ D T ++++ YNRI+ IE K + D PL I PTI +D
Sbjct: 326 IVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKEGAKLVLGDEPLPLKQGYFISPTIFAD 385
Query: 349 VSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIR 408
S + + E FGP++ I ++ DE I+ L FT + + +
Sbjct: 386 CSENMTIVKEEIFGPVVAISKFKTEDEAIEK-ANNTTYGLAAMCFTKDLERAHRVSDELE 444
Query: 409 SGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+G +N T +APFGGI SG GN G + +T + +
Sbjct: 445 AGMVFINST--ENSDIQAPFGGIKMSGIGNELGSNGIEMYTQIKAV 488
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 138 bits (347), Expect = 2e-32
Identities = 111/349 (31%), Positives = 159/349 (44%), Gaps = 17/349 (4%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQV 182
+G I P+NFP+L+ L A+A GN+VV K +E TP A ++ ++ +EA G V
Sbjct: 166 IGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSALLVGKLLHEAGLPDGVV 225
Query: 183 ETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFIS 240
V G GA +A+ DK+ +TGST VG II E A+KS L LELGGKSP +
Sbjct: 226 NIVSGFGATAGAAIASHMDVDKVAFTGSTDVGKIILELASKSNLKAVTLELGGKSPFIVC 285
Query: 241 PNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCK--KVLNEFYPSV 298
+ Q A+ +++ N GQ C A + +YDEFV+ K +
Sbjct: 286 EDADVDQ---AVELAHFALFFNQGQCCCAGSRTFVHERVYDEFVEKAKARALKRNVGDPF 342
Query: 299 TSDTEYTHMIHERAYNRIQTVIE-TTKGQKTVAQHSDNL--PPLCIPPTIISDVSWDDPS 355
S E + +N+I I+ + T+ D L I PT+ SDV D
Sbjct: 343 KSGIEQGPQVDSEQFNKILKYIKHGVEAGATLQAGGDRLGSKGYYIQPTVFSDVKDDMLI 402
Query: 356 MTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVN 415
T E FGP+ I+++ DLDE I L +FT + D ++ +R G +N
Sbjct: 403 ATDEIFGPVQTILKFKDLDEVI-ARANNSRYGLAAGVFTQNLDTAHRLMRALRVGTVWIN 461
Query: 416 DTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHER---TIFKQPFWV 461
V PFGG SG G G Y+ + + T K P W+
Sbjct: 462 --CFDVLDASIPFGGYKMSGIGREKGIYSLNNYLQVKAVVTSLKNPAWL 508
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 135 bits (341), Expect = 1e-31
Identities = 102/345 (29%), Positives = 165/345 (47%), Gaps = 14/345 (4%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA- 176
F +G I+P+NFP+L+ + LA A+ GN++V KP+E TP A + + EA
Sbjct: 165 FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAG 224
Query: 177 FEKGQVETVQGGAEETSALVES-GKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGK 234
F G V V G A + S + +KI +TGST VG ++ E A++S L LELGGK
Sbjct: 225 FPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGK 284
Query: 235 SPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEF 294
+P + + + + A+ + N GQ C AA V + +Y EFV + +
Sbjct: 285 NPCIVCAD---ADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKR 341
Query: 295 YPSVTSD--TEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNL---PPLCIPPTIISDV 349
D TE I ++ +++I +IE+ K + + + L I PT+ S+V
Sbjct: 342 PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEV 401
Query: 350 SWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRS 409
+ + E FGP+ PI+++ ++E I D L +FT + D+ + + + S
Sbjct: 402 TDNMRIAKEEIFGPVQPILKFKSIEEVIKR-ANSTDYGLTAAVFTKNLDKALKLASALES 460
Query: 410 GACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
G +N + +APFGG SG G G Y +T +T+
Sbjct: 461 GTVWIN--CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 135 bits (340), Expect = 1e-31
Identities = 131/441 (29%), Positives = 203/441 (45%), Gaps = 29/441 (6%)
Query: 28 ARLAQSKSP--RATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPL 85
ARLA S R D +ER R L KL V+ + L S + + + ++L +
Sbjct: 84 ARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGV 143
Query: 86 YNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLA 145
Y +I I V +F TF +G I P+NFP+L+ +A
Sbjct: 144 IKTFRYYA-GWADKIHGMTIPVD--GDYF--TFTRHEPIGVCGQIIPWNFPLLMFAWKIA 198
Query: 146 GAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG-GAEETSALVESGKFDK 203
A+ GN+VV KP+E TP A M + EA F G + + G G +A+ DK
Sbjct: 199 PALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDK 258
Query: 204 IFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGN 262
I +TGST VG +I E A +S L LELGGKSP I + + A+ + + N
Sbjct: 259 IAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNII---FADADLDYAVEQAHQGVFFN 315
Query: 263 AGQICVAADYVLCPDSIYDEF----VDSCKK--VLNEFYPSVTSDTEYTHMIHERAYNRI 316
GQ C A + +SIY+EF V+ K+ V + F P+ TE I ++ YN+I
Sbjct: 316 QGQCCTAGSRIFVEESIYEEFVRRSVERAKRRIVGSPFDPT----TEQGPQIDKKQYNKI 371
Query: 317 QTVIET--TKGQKTVAQHSD-NLPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDL 373
+I++ +G K I PT+ S+V+ D E FGP+ I+R+ +
Sbjct: 372 LELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTM 431
Query: 374 DETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGT 433
DE I+ D LV +FTN ++ + + +++G +N + ++PFGG
Sbjct: 432 DEVIER-ANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWIN--CYNALNAQSPFGGFKM 488
Query: 434 SGYGNYHGPYTFKTFTHERTI 454
SG G G + + ++ +T+
Sbjct: 489 SGNGREMGEFGLREYSEVKTV 509
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 131 bits (330), Expect = 2e-30
Identities = 115/444 (25%), Positives = 198/444 (43%), Gaps = 29/444 (6%)
Query: 13 PGKIELAKQFYRSRQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHR 72
P ++E R Q AQS R + L+ L + +++E + +S+D +
Sbjct: 85 PTEVEERVTLSRKAQKTWAQSS------FKLRRQFLRILLKYIIEHQELICEVSSRDTGK 138
Query: 73 ARSETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISP 132
+ E++ I +L+ ++ ++P+ + S A + VE LG + I P
Sbjct: 139 TMVDASLGEIMTTCEKITWLLSEGERWLKPES-RSSGRAMLHKVSRVEFHPLGVIGAIVP 197
Query: 133 FNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFE-----KGQVETVQG 187
+N+P +P+ A+ GN +V K SE I A + V+ + G
Sbjct: 198 WNYPFHNIFNPMLAAVFSGNGIVIKVSEHASWSGCFYFRIIQAALAAVGAPENLVDVITG 257
Query: 188 GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQ 247
AE ALV S DK+ + GST VG +I AA++LTP LELGGK I + S
Sbjct: 258 FAETGEALVSS--VDKMIFVGSTAVGKMIMRNAAETLTPVTLELGGKDAFIICEDADVSH 315
Query: 248 -WETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFY--PSVTSDTEY 304
+ A+R ++ ++GQ C A+ IY F+ K++ P +T +
Sbjct: 316 VAQVAVR----GTLQSSGQNCAGAERFYVHKDIYTAFIGQVTKIVKSVSAGPPLTGRYDM 371
Query: 305 THMIHERAYNRIQTVIETT--KGQKTVAQHS-----DNLPPLCIPPTIISDVSWDDPSMT 357
+ + +Q+++ KG + + S ++ PPT++ +V+ + M
Sbjct: 372 GAICLQEHSEHLQSLVNDALDKGAEIAVRGSFGHLGEDAVDQYFPPTVLINVNHNMKIMK 431
Query: 358 GENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDT 417
E FGPI+PIM+++ DE + L L +F+ SK I ++I+ G +ND
Sbjct: 432 EEAFGPIMPIMQFS-TDEEVIKLANDSRYALGCAVFSGSKHRAKQIASQIQCGVAAINDF 490
Query: 418 LLHVGIEEAPFGGIGTSGYGNYHG 441
+ + PFGG+ SG+G + G
Sbjct: 491 ASNYMCQSLPFGGVKDSGFGRFAG 514
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 130 bits (326), Expect = 6e-30
Identities = 98/330 (29%), Positives = 156/330 (46%), Gaps = 19/330 (5%)
Query: 119 VEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-F 177
V K +G +I+P+NFP+ + A+A G +VV KPSE TP A + ++ +A
Sbjct: 163 VMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGI 222
Query: 178 EKG--QVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
KG V T A +S I +TGST VG ++ +A + LELGG +
Sbjct: 223 PKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNA 282
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLN--E 293
P + + E A+ S N GQ CV+A+ DS+YD+FV KK + +
Sbjct: 283 PFIV---FDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALK 339
Query: 294 FYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQK-TVAQHSDNLP---PLCIPPTIISDV 349
D + +I+E +N++ +E + +K + LP L PTI++DV
Sbjct: 340 IGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDV 399
Query: 350 SWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDT--PLVQYIFTNSKDEIDHILTRI 407
+ E FGP++ I+R+ D +E + K DT L Y ++ + ++ + R+
Sbjct: 400 PPSAQLYSEEVFGPVVSIIRFRDEEEAVK---KANDTRRGLAGYFYSENLQQVFRVAKRL 456
Query: 408 RSGACVVNDTLLHVGIEEAPFGGIGTSGYG 437
G VN+ + + EAPFGG+ SG G
Sbjct: 457 EVGMVGVNEGI--ISAAEAPFGGVKESGVG 484
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 128 bits (322), Expect = 2e-29
Identities = 110/350 (31%), Positives = 163/350 (46%), Gaps = 22/350 (6%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
T+ +G I P+NFP+L+ LA A+A GN+VV K + TP A + + EA
Sbjct: 189 TYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSALHVASLIKEA 248
Query: 177 -FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGG 233
F +G V + G G + A+ DK+ +TGST VG I + AA+S + LELGG
Sbjct: 249 QFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAESNVKKVTLELGG 308
Query: 234 KSP--VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVL 291
KSP VF +L E A+R+ +++ N GQ C A IYDEFV K+++
Sbjct: 309 KSPNIVFADADL-----EEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFVAKAKELV 363
Query: 292 NEFYPSVTSDTEYTH--MIHERAYNRIQTVIETTK--GQKTV---AQHSDNLPPLCIPPT 344
+ D T I E I IE+ K G + V +H D + PT
Sbjct: 364 EKTVIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGDQ--GYFVKPT 421
Query: 345 IISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHIL 404
I ++V+ E FGP++ ++R+ ++E I+ L + TN ++ +
Sbjct: 422 IFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTI-YGLAAGVVTNDLNKALQVA 480
Query: 405 TRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
IR+G+ VN V APFGG SG G G Y +T +T+
Sbjct: 481 NTIRAGSVWVN--CYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTV 528
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 128 bits (321), Expect = 2e-29
Identities = 125/439 (28%), Positives = 189/439 (42%), Gaps = 41/439 (9%)
Query: 26 RQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAA----ASKDFHRARSETLT-- 79
+ AR A T +R L L +++ ++ L A A K FH + L
Sbjct: 65 KAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQI 124
Query: 80 IELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILL 139
IEL Y + NM + I L + F T K+ G V I P+N+P+ +
Sbjct: 125 IELTRYYAGAVDKF-NMGETIP-------LTFNKFAYTL--KVPFGVVAQIVPWNYPLAM 174
Query: 140 ALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG-GAEETSALVE 197
A + GA+A GN+V+ KP+E T + +A F G V + G G+ AL
Sbjct: 175 ACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGT 234
Query: 198 SGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFISPNLPKSQWETAIRRIY 256
DKI +TGST VG + E + +S L LE GGKSP + + + AI +
Sbjct: 235 HMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALV---FEDADLDKAIEWVA 291
Query: 257 YSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSVTSDTEYTH------MIHE 310
N+GQIC A V SIYD+FV+ K+ + + + +I
Sbjct: 292 NGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISS 351
Query: 311 RAYNRIQTVIETTKGQKTVAQHSDNLPPL------CIPPTIISDVSWDDPSMTGENFGPI 364
Y+RI++ IE K ++ + + P+ IPPTI +DV + E FGP+
Sbjct: 352 TQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPV 411
Query: 365 LPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIE 424
+ + ++T+ D+ + L L +FT + I++G +N T E
Sbjct: 412 VVVSKFTNYDDAL-KLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQT----NQE 466
Query: 425 EA--PFGGIGTSGYGNYHG 441
EA PFGG SG G G
Sbjct: 467 EAKVPFGGFKMSGIGRESG 485
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 128 bits (321), Expect = 2e-29
Identities = 119/448 (26%), Positives = 196/448 (43%), Gaps = 55/448 (12%)
Query: 51 LYWAVKDNEERLIAAASKDFH----------RARSETLTIELVPLYNNILYLIKNMK--K 98
+Y A++D+ + +AAA K F RA++ +LV + L I++M K
Sbjct: 75 VYKAMEDDVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGK 134
Query: 99 EIEPKKIKVSLLAHWFGT--------------------TFVEKIALGTVLVISPFNFPIL 138
+ + V+L++ + + T+ K LG I P+NFP+L
Sbjct: 135 SLFCARGDVALVSKYLRSCGGWADKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLL 194
Query: 139 LALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG-GAEETSALV 196
+ + A+A GN+VV KP+E TP A ++C EA G V + G G L
Sbjct: 195 MWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLS 254
Query: 197 ESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSP--VFISPNLPKSQWETAIRR 254
KI +TGST G I + AA ++ LELGGKSP VF +L K A++
Sbjct: 255 AHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVFADADLDK-----AVKN 309
Query: 255 IYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSVTSDTEYTH--MIHERA 312
I + N+G++C A + D++Y+E + K D E ++
Sbjct: 310 IAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQ 369
Query: 313 YNRIQTVIETTK--GQKTV---AQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPI 367
++I ++ K G + V A+H + PT+ +DV D + E FGPI+ +
Sbjct: 370 LHKILDYVDVAKSEGARLVTGGARHGSK--GYFVKPTVFADVKGDMRIVKEEVFGPIVTV 427
Query: 368 MRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVND-TLLHVGIEEA 426
+++ +DE I + L I TN ++ + R+++G +N H +
Sbjct: 428 SKFSTVDEVI-AMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFH---QNV 483
Query: 427 PFGGIGTSGYGNYHGPYTFKTFTHERTI 454
PFGG G SG G G +T +++
Sbjct: 484 PFGGFGQSGIGREMGEAALSNYTQTKSV 511
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 125 bits (314), Expect = 2e-28
Identities = 119/436 (27%), Positives = 193/436 (43%), Gaps = 34/436 (7%)
Query: 43 ERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIKNMKKEIEP 102
ER R L + V+ + E L + + D + ++LT E +P++ + +I
Sbjct: 120 ERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAE-IPMFARLFRYYAGWADKIHG 178
Query: 103 KKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELT 162
I ++ T E I + ++ P+NFP+L+ + A+A GN++V K +E T
Sbjct: 179 LTIPAD--GNYQVHTLHEPIGVAGQII--PWNFPLLMFAWKVGPALACGNTIVLKTAEQT 234
Query: 163 PACAEVMEEICNEA-FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKA 220
P A ++ EA G + V G GA +AL DK+ +TGST G +I A
Sbjct: 235 PLTAFYAGKLFLEAGLPPGVLNIVSGFGATAGAALASHMDVDKLAFTGSTDTGKVILGLA 294
Query: 221 AKS-LTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSI 279
A S L P LELGGKSP + + + A+ +++ N GQ C A + +
Sbjct: 295 ANSNLKPVTLELGGKSPFIV---FEDADIDKAVELAHFALFFNQGQCCCAGSRTFVHEKV 351
Query: 280 YDEFVDSCKK------VLNEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHS 333
YDEFV+ K V + F + + E+ I++ IE+ T+
Sbjct: 352 YDEFVEKSKARALKRVVGDPFRKGIEQGPQIDLKQFEKVMKYIKSGIES---NATLECGG 408
Query: 334 DNL--PPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP---L 388
D + I PT+ S+V D E FGP+ I++++D+DE +IKR + L
Sbjct: 409 DQIGDKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDE----VIKRANETKYGL 464
Query: 389 VQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTF 448
+FT + D + + +++G VN V PFGG SG G G Y+ +
Sbjct: 465 AAGVFTKNLDTANRVSRALKAGTVWVN--CFDVFDAAIPFGGYKMSGNGREKGIYSLNNY 522
Query: 449 THER---TIFKQPFWV 461
+ T +P W+
Sbjct: 523 LQIKAVVTALNKPAWI 538
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 124 bits (312), Expect = 3e-28
Identities = 122/447 (27%), Positives = 191/447 (42%), Gaps = 31/447 (6%)
Query: 26 RQARLAQSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPL 85
+ AR A T +R L L +++ ++ L A + D + +L +
Sbjct: 65 KAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQI 124
Query: 86 YNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLA 145
Y + K K + L + F T K+ G V I P+N+P+ +A L
Sbjct: 125 LQLTRYFAGSADKF--DKGATIPLTFNKFAYTL--KVPFGVVAQIVPWNYPLAMACWKLQ 180
Query: 146 GAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG-GAEETSALVESGKFDK 203
GA+A GN+V+ KP+E T + +A F G V V G G+ AL DK
Sbjct: 181 GALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDK 240
Query: 204 IFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSP--VFISPNLPKS-QWETAIRRIYYSS 259
I +TGST VG + E + +S L LE GGKSP VF +L K+ W A I+Y
Sbjct: 241 ISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAA--GIFY-- 296
Query: 260 MGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSVTSDTEYTH------MIHERAY 313
N+GQ C A V SIYD+FV+ K+ + + + +I Y
Sbjct: 297 --NSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQY 354
Query: 314 NRIQTVIETTKGQKTVAQHSDNLPPL------CIPPTIISDVSWDDPSMTGENFGPILPI 367
+RI++ IE K ++ + + P+ IPPTI +DV + E FGP++ +
Sbjct: 355 DRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVV 414
Query: 368 MRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAP 427
++T+ D+ + L L +FT + I++G +N + + P
Sbjct: 415 SKFTNYDDAL-KLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSS--NDEDVTVP 471
Query: 428 FGGIGTSGYGNYHGPYTFKTFTHERTI 454
FGG SG G G T+ + +
Sbjct: 472 FGGFKMSGIGRELGQSGVDTYLQTKAV 498
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 124 bits (311), Expect = 3e-28
Identities = 95/351 (27%), Positives = 157/351 (44%), Gaps = 22/351 (6%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA- 176
+ + LG + I +N+P +A A A+A GN++VFKPS TP A ++ EI +EA
Sbjct: 140 YTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAG 199
Query: 177 FEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSP 236
G VQGGA L + K+ +TGS G I E +AK + P LELGGKSP
Sbjct: 200 VPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSP 259
Query: 237 VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLN--EF 294
+ I A++ ++ GQ+C V I D+F + K +
Sbjct: 260 LII---FSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKI 316
Query: 295 YPSVTSDTEYTHMIHERAYNRIQTVIETTK--GQKTVAQHSDNLPP-------LCIPPTI 345
+ DT +I+ R+ ++ K G K + +P + P +
Sbjct: 317 GDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCV 376
Query: 346 ISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP--LVQYIFTNSKDEIDHI 403
+++ D + E FGP++ I+ + D + L + DT L +FT +
Sbjct: 377 LTNCRDDMTCVKEEIFGPVMSILSF---DTEAEVLERANDTTFGLAAGVFTRDIQRAHRV 433
Query: 404 LTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+ +++G C +N+ +V E PFGG SG+G +G T + ++ +T+
Sbjct: 434 VAELQAGTCFINN--YNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTV 482
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 124 bits (311), Expect = 3e-28
Identities = 100/337 (29%), Positives = 152/337 (44%), Gaps = 22/337 (6%)
Query: 130 ISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG- 187
I P+NFP+L+ L A+A GN VV K +E TP A + + EA F G V V G
Sbjct: 182 IIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGF 241
Query: 188 GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFISPNLPKS 246
G +A+ DK+ +TGST +G +I A S L LELGGKSP I + +
Sbjct: 242 GPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNII---MSDA 298
Query: 247 QWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVD------SCKKVLNEFYPSVTS 300
+ A+ + +++ N GQ C A + IYDEFV+ + V N F S
Sbjct: 299 DMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPF----DS 354
Query: 301 DTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPP---LCIPPTIISDVSWDDPSMT 357
TE + E + +I I T K + + I PT+ DV
Sbjct: 355 KTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAK 414
Query: 358 GENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDT 417
E FGP++ I+++ ++E + L +FT D+ +++ +++G VN
Sbjct: 415 EEIFGPVMQILKFKTIEEVVGR-ANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVN-- 471
Query: 418 LLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
V ++PFGG SG G G Y + +T +T+
Sbjct: 472 CYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTV 508
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 123 bits (308), Expect = 8e-28
Identities = 108/352 (30%), Positives = 162/352 (45%), Gaps = 24/352 (6%)
Query: 99 EIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKP 158
E + +KV L + F ++ G + VI+P+NFP+ +AL L AIA GN VV KP
Sbjct: 138 ETDNPTVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKP 197
Query: 159 SELTPACAEVMEEICNEA-FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTII 216
SEL P IC EA G + + G G E +AL K + +TGS G I
Sbjct: 198 SELAPWSCLEFALICKEAGLPDGVLNVIIGSGKESGAALSCHPKIAYLAFTGSLATGKKI 257
Query: 217 AEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCP 276
AA+++ P LELGGKSP+ I + S AI ++ N G+ C AA ++
Sbjct: 258 MHAAAENIVPLTLELGGKSPLIICEDADLS---LAIPSAAFAIFFNQGEACTAASRLIVH 314
Query: 277 DSIYDE----FVDSCKKVL--NEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVA 330
+S+ DE V K++ N P VT + E+ + IQ+ I +G K V
Sbjct: 315 ESVADEVLGGLVSEANKLIIGNGLDPQVTLGPVVSKTQFEKIVSYIQSAI--NEGCKCVV 372
Query: 331 QHSDNLP-----PLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFD 385
LP IPPT+ ++V + E FGP+L + + +E ++ L +
Sbjct: 373 ---GGLPRSEQKGYFIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALE-LANDSE 428
Query: 386 TPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYG 437
L +F+ + ++ I +G C +N+ HV E P+ G SG G
Sbjct: 429 YGLGSGVFSTNPKTLEFFSNNIEAGMCSLNN--YHVVTHELPWIGWKHSGLG 478
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 122 bits (307), Expect = 1e-27
Identities = 100/337 (29%), Positives = 151/337 (44%), Gaps = 22/337 (6%)
Query: 130 ISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG- 187
I P+NFP+L+ L A+A GN VV K +E TP A + + EA F G V V G
Sbjct: 181 IIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGF 240
Query: 188 GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFISPNLPKS 246
G +A+ DK+ +TGST +G +I A S L LELGGKSP I + +
Sbjct: 241 GPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNII---MSDA 297
Query: 247 QWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFV------DSCKKVLNEFYPSVTS 300
+ A+ + +++ N GQ C A + IYDEFV + V N F S
Sbjct: 298 DMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPF----DS 353
Query: 301 DTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPP---LCIPPTIISDVSWDDPSMT 357
TE + E + +I I T K + + I PT+ DV
Sbjct: 354 KTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAK 413
Query: 358 GENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDT 417
E FGP++ I+++ ++E + L +FT D+ +++ +++G VN
Sbjct: 414 EEIFGPVMQILKFKTIEEVVGR-ANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVN-- 470
Query: 418 LLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
V ++PFGG SG G G Y + +T +T+
Sbjct: 471 CYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTV 507
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 119 bits (299), Expect = 8e-27
Identities = 102/351 (29%), Positives = 158/351 (44%), Gaps = 26/351 (7%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA- 176
F +G I P+NFP+++ LA A+A GN+VV K +E TP A + + EA
Sbjct: 170 FTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAG 229
Query: 177 FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGK 234
F G V + G G +A+ + DK+ +TGST VG +I + A S L LELGGK
Sbjct: 230 FPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGK 289
Query: 235 SPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSC------K 288
SP + L + E A+ + + + N GQ C A +SIY+EF++ +
Sbjct: 290 SPSIV---LADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQR 346
Query: 289 KVLNEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQ-----HSDNLPPLCIPP 343
KV N F DT+ + + + R+ I+ GQK A+ I P
Sbjct: 347 KVGNPF----ELDTQQGPQVDKEQFERVLGYIQL--GQKEGAKLLCGGERFGERGFFIKP 400
Query: 344 TIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHI 403
T+ V D E FGP+ P+ ++ ++E ++ L +FT D+ +
Sbjct: 401 TVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVER-ANNTRYGLAAAVFTRDLDKAMYF 459
Query: 404 LTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+++G VN ++ PFGG SG G G K +T +T+
Sbjct: 460 TQALQAGTVWVN--TYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTV 508
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 119 bits (298), Expect = 1e-26
Identities = 102/344 (29%), Positives = 159/344 (45%), Gaps = 24/344 (6%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNE-AFEKGQV 182
+G I P+NFP L+ +A A+A GN+++ K +ELTP A + + E F G +
Sbjct: 161 IGVCGQIIPWNFPFLMCAWKIAPAVACGNTIILKTAELTPLSALCLTKFVPECGFPPGVI 220
Query: 183 ETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFIS 240
+ G G +A+ DK+ +TGST VG ++ AA S L LELGGKSP +
Sbjct: 221 NVLSGDGRRCGNAISSHMDIDKVAFTGSTGVGRMVMRAAASSNLKKVTLELGGKSPNIV- 279
Query: 241 PNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDS--CKKVLNEFYPSV 298
+ ++A Y N+GQ+C A V + +YDEF+ K +
Sbjct: 280 --FNDADLDSAAVWTNYGIFYNSGQVCCAGSRVYVQEDVYDEFIKRMVAKAKTLKVGDPF 337
Query: 299 TSDTEYTHMIHERAYNRIQTVIET--TKGQKTV--AQHSDNLPPLCIPPTIISDVSWDDP 354
DT + ++ Y RI + IE+ G K + NL + PTI+S+V+ D
Sbjct: 338 AEDTFQGAQVSKQQYERIVSYIESGIAHGAKLEIGGKRHGNL-GYFVEPTILSNVTEDMA 396
Query: 355 SMTGENFGPILPIMRYTDLDETIDTLIKRFDTP---LVQYIFTNSKDEIDHILTRIRSGA 411
E FGP+L ++++ +TI+ I+R + L + TN+ + + +G
Sbjct: 397 VGKEEIFGPVLAVIKF----KTIEEAIRRGNNSTYGLAAGVHTNNITNAIKVSNALEAGT 452
Query: 412 CVVN-DTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
VN LLH + PFGG SG G G Y +T + +
Sbjct: 453 VWVNCYNLLH---HQIPFGGYKESGIGRELGSYGLTNYTQTKAV 493
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 119 bits (298), Expect = 1e-26
Identities = 121/457 (26%), Positives = 193/457 (41%), Gaps = 45/457 (9%)
Query: 30 LAQSKSPRATDINERIRSLQKLY-----WAVKD---------------NEERLIAAASKD 69
LAQ TD+N +++ Q + W D +R+I A+ +
Sbjct: 58 LAQVAEGDKTDVNIAVKAAQNAFRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLES 117
Query: 70 FHRARSETLTIEL-VPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVL 128
+ + +PL L L++ M + K I + +F T+ +G
Sbjct: 118 LDNGKPYAVAYNADLPLSIKTLRLLRRMADKNHGKTIPIE--GDYF--TYTRHEPVGVCG 173
Query: 129 VISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG 187
I P+NFP+L+ L A+A GN+VV K +E TP A + + EA F G V + G
Sbjct: 174 QIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPG 233
Query: 188 -GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSPVFISPNLPK 245
G A+ DK+ +TGST VG ++ + AA+S + LELGGKSP I
Sbjct: 234 YGHTAGQAISSHMDVDKVAFTGSTEVGRLVMKAAAESNVKKVTLELGGKSPNII---FAD 290
Query: 246 SQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSVTSDTEYT 305
+ ++ + + N GQ C A IYD+FV K++ + D + T
Sbjct: 291 ADLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKIYDDFVARSKELAEKAVIGDPFDLKTT 350
Query: 306 HMIHERAYNRIQTVIE-TTKGQKTVAQ-------HSDNLPPLCIPPTIISDVSWDDPSMT 357
+++T+++ G+K AQ H D + PTI ++V
Sbjct: 351 QGPQVDG-KQVETILKYIAAGKKDGAQLVTGGAKHGDQ--GHFVKPTIFANVKDQMTIAQ 407
Query: 358 GENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDT 417
E FGP++ I+R+ ++E ++ L + T D+ HI R+G+ VN
Sbjct: 408 EEIFGPVMTIIRFDTMEELVEKANNTI-YGLAAGVMTKDIDKALHIANATRAGSVWVN-- 464
Query: 418 LLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
V APFGG SG G G Y + +T +T+
Sbjct: 465 CYDVFDAAAPFGGFKQSGIGRELGEYGLEAYTEVKTV 501
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 119 bits (297), Expect = 1e-26
Identities = 100/342 (29%), Positives = 155/342 (45%), Gaps = 29/342 (8%)
Query: 119 VEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFE 178
V K +G VI+P+NFP + + A+A G +VV KP+E TP A + E+ ++A
Sbjct: 190 VLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGI 249
Query: 179 KGQVETV-----QGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGG 233
V V + E A+ KI +TGSTT G I+ AA S+ +ELGG
Sbjct: 250 PSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGG 309
Query: 234 KSP--VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFV----DSC 287
+P VF S N+ + A+ S N GQ CV ++ L I+D FV ++
Sbjct: 310 LAPFIVFDSANV-----DQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAM 364
Query: 288 KKVL---NEFYPSVTSDTEYTHMIHERAYNRIQTVIE--TTKGQKTV-AQHSDNLPPLCI 341
KK L N F T +I+E+A +++ + +KG V L
Sbjct: 365 KKNLRVGNGFEEGTTQGP----LINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFF 420
Query: 342 PPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEID 401
PT++ +V+ D E FGP+ P++++ D +E + D L Y ++ +I
Sbjct: 421 EPTLLCNVTQDMLCTHEETFGPLAPVIKF-DTEEEAIAIANAADVGLAGYFYSQDPAQIW 479
Query: 402 HILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPY 443
+ ++ G VN+ L + E PFGG+ SG G Y
Sbjct: 480 RVAEQLEVGMVGVNEGL--ISSVECPFGGVKQSGLGREGSKY 519
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 117 bits (293), Expect = 4e-26
Identities = 91/340 (26%), Positives = 151/340 (43%), Gaps = 15/340 (4%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA- 176
++ K +G V +I+P+N+P+L+A+ +A ++A G + + KPSEL + +IC E
Sbjct: 146 YILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPSELASLTCLELADICREVG 205
Query: 177 FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
G + + G G E + L DKI +TGSTT G+ I AAK + P LELGGKS
Sbjct: 206 LPPGVLNILTGLGTEAGAPLASHPHVDKIVFTGSTTTGSSIMTSAAKLVKPVSLELGGKS 265
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFY 295
P+ + ++ + A+ + GQIC A +L + I DEF+D K
Sbjct: 266 PIIVFDDV---DIDKAVEWTMFGCFWTNGQICSATSRLLVHERIADEFLDKLVKWTKNIK 322
Query: 296 PS--VTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPP-----LCIPPTIISD 348
S ++ + Y R+ + + + P + P I+S+
Sbjct: 323 ISDPFEEGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGGVRPEHLKKGYFVEPAIVSN 382
Query: 349 VSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIR 408
V+ E FGP L + ++ DE I L L + +N + D + +
Sbjct: 383 VTTSMEIWREEVFGPALCVKTFSTEDEAIQ-LANDSQYGLAGAVLSNDLERCDRVSKAFQ 441
Query: 409 SGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTF 448
+G VN + +AP+GG SG+G G + + +
Sbjct: 442 AGIVWVNCS--QPCFCQAPWGGTKRSGFGRELGEWGLENY 479
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 117 bits (292), Expect = 5e-26
Identities = 111/409 (27%), Positives = 188/409 (45%), Gaps = 25/409 (6%)
Query: 43 ERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIKNMKKEIEP 102
ER R + +L +++N+E L + D + L + Y K I+
Sbjct: 505 ERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDK-IQG 563
Query: 103 KKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELT 162
I ++ TF +K LG +I P+N+P+++ A +A GN++V KP+++T
Sbjct: 564 STIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVT 623
Query: 163 PACAEVMEEICNEA-FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKA 220
P A E+ +A F KG + + G G L E K+ +TGST +G I +
Sbjct: 624 PLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSC 683
Query: 221 AKS-LTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSI 279
A S L LELGGKSP+ I + + A+R + N G+ C+AA + +SI
Sbjct: 684 AVSNLKKVSLELGGKSPLII---FNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESI 740
Query: 280 YDEFVDSCKKVLNEFYPSVTSD-----TEYTHMIHERAYNRIQTVIET-TKGQKTVAQHS 333
+DEFV +V+ E D T++ H+ ++ ET K T+
Sbjct: 741 HDEFV---TRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGG 797
Query: 334 DNL--PPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP---L 388
+ P + PT+ +DV E+FGPI+ I ++ + D ID +++R ++ L
Sbjct: 798 RQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGD--IDGVLQRANSTEYGL 855
Query: 389 VQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYG 437
+FT ++ ++ ++ +G +N T + APFGG+ SG+G
Sbjct: 856 ASGVFTRDINKAMYVSEKLEAGTVFIN-TYNKTDV-AAPFGGVKQSGFG 902
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 115 bits (287), Expect = 2e-25
Identities = 100/336 (29%), Positives = 155/336 (45%), Gaps = 29/336 (8%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
++ ++ LG I P+NFP+L+ +A A+ GN+VV K +E TP A + + +A
Sbjct: 175 SYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQA 234
Query: 177 -FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGK 234
G + V G G A+ K K+ +TGST G I + AA L LELGGK
Sbjct: 235 GIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGK 294
Query: 235 SP--VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCK---- 288
SP VF L K+ + I IYY N+G++C A V +SIYD+F++ K
Sbjct: 295 SPNIVFADAELKKAV-QNIILGIYY----NSGEVCCAGSRVYVEESIYDKFIEEFKAASE 349
Query: 289 --KVLNEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQ-KTVAQHSDNL--PPLCIPP 343
KV + F S + + M N+I ++ K + T+ + L I P
Sbjct: 350 SIKVGDPFDESTFQGAQTSQM----QLNKILKYVDIGKNEGATLITGGERLGSKGYFIKP 405
Query: 344 TIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHI 403
T+ DV D + E FGP++ + ++ DE I+ + + L I T++ + +
Sbjct: 406 TVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVIN-MANDSEYGLAAGIHTSNINTALKV 464
Query: 404 LTRIRSGACVVN--DTLLHVGIEEAPFGGIGTSGYG 437
R+ +G +N + H PFGG SG G
Sbjct: 465 ADRVNAGTVWINTYNDFHHA----VPFGGFNASGLG 496
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 115 bits (287), Expect = 2e-25
Identities = 91/334 (27%), Positives = 153/334 (45%), Gaps = 19/334 (5%)
Query: 121 KIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKG 180
K +G V +I+P+NFP + + A+A G +VV +P+ TP A + ++ A
Sbjct: 157 KQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPFTALALAKLAERAGVPA 216
Query: 181 QV---ETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPV 237
V T +E L + K+ +TGST VG I+A++++ +L LELGG +P
Sbjct: 217 GVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQSSSTLKKLSLELGGNAPF 276
Query: 238 FISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPS 297
+ + E A + +GQ CV A+ + S+YD FVD + +++F
Sbjct: 277 IV---FEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAFVDLVTERVSKFKLG 333
Query: 298 VTSDTEYTH--MIHERAYNRIQTVIE--TTKGQKTV--AQHSDNLPPLCIPPTIISDVSW 351
D TH +I E+A ++++ +E KG V + + NL P+ PT+I +
Sbjct: 334 YGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLGPMYFEPTVIINAKQ 393
Query: 352 DDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP--LVQYIFTNSKDEIDHILTRIRS 409
E FGP+ + ++ DE + D+P L Y+F+ + + ++
Sbjct: 394 GMLISEEETFGPVGALFKFDTEDEVV---AWANDSPVGLAGYLFSKDISRVFRVGEALQV 450
Query: 410 GACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPY 443
G N L V +PFGG+ SG+G Y
Sbjct: 451 GMVGCNTGL--VSDVLSPFGGVKESGFGREGSKY 482
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 114 bits (286), Expect = 3e-25
Identities = 108/456 (23%), Positives = 198/456 (42%), Gaps = 30/456 (6%)
Query: 14 GKIELAKQFYRSRQARLA-QSKSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHR 72
GK E+ +R+A + S+SP+ ER R L ++ ++ + E A SKD +
Sbjct: 43 GKDEIEAAVKAAREAFPSWSSRSPQ-----ERSRVLNQVADLLEQSLEEFAQAESKDQGK 97
Query: 73 ARSETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISP 132
+ T+++ N + + + + + H + + +G +ISP
Sbjct: 98 TLALARTMDIPRSVQNFRFFASSSLHHTS----ECTQMDHLGCMHYTVRAPVGVAGLISP 153
Query: 133 FNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVETVQG-GAE 190
+N P+ L +A A+A GN+V+ KPSELT A ++ ++ ++A G V V G G
Sbjct: 154 WNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPR 213
Query: 191 ETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWET 250
ALV + I +TGS I + +A LELGGK+P I + +
Sbjct: 214 VGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAII---FEDANLDE 270
Query: 251 AIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSVTSD--TEYTHMI 308
I SS N G+IC+ + SIY EF+ + ++ + SD +I
Sbjct: 271 CIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALI 330
Query: 309 HERAYNRIQTVIETTKGQKTVAQHSDNLPPLCIP----------PTIISDVSWDDPSMTG 358
+ ++++ ++ + + + L +P PT+I+D+ + MT
Sbjct: 331 SKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTE 390
Query: 359 ENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTL 418
E FGP+ ++ + +E I+ L +++++ + + +++SG N L
Sbjct: 391 EIFGPVTCVVPFDSEEEVIER-ANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWL 449
Query: 419 LHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+ PFGG+ +SG G ++ FT +TI
Sbjct: 450 IRE--LNLPFGGMKSSGIGREGAKDSYDFFTEIKTI 483
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 113 bits (283), Expect = 6e-25
Identities = 103/447 (23%), Positives = 192/447 (42%), Gaps = 22/447 (4%)
Query: 11 SIPGKIELAKQFYRSRQARLAQS--KSPRATDINERIRSLQKLYWAVKDNEERLIAAASK 68
S+ G+++L + + LA+ K ++T ER L+ L + N+++ A K
Sbjct: 14 SLLGEVKLFNKSDIDQSIILAEEAQKEWKSTSFAERRNFLKALKENIIRNQDKYAEIACK 73
Query: 69 DFHRARSETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTTFVEKIALGTVL 128
D + + E++ I + + N ++ + P K SLL + G +V+ LG +
Sbjct: 74 DTGKTLVDAAFGEILVTLEKINWTLANGEQSLRPTKRPNSLLTSYKGG-YVKYEPLGVIA 132
Query: 129 VISPFNFPILLALDPLAGAIAGGNSVVFKPSELTP-----ACAEVMEEICNEAFEKGQVE 183
+ +N+P+ AL P+ A+ GN++V K SELT C V + + V+
Sbjct: 133 ALVSWNYPLHNALGPIISALFAGNAIVVKGSELTAWSTHQYCEMVRSLLQSMGHSPELVQ 192
Query: 184 TVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNL 243
+ + L I + GS + ++A AAK LTP LELGGK P ++ +
Sbjct: 193 CITCLPDVADHLTSHSGIKHITFIGSQPIAKLVAASAAKQLTPLCLELGGKDPCILTDDH 252
Query: 244 PKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSV--TSD 301
+ + + R + S AGQ C+ + ++ D +YD + ++ + +D
Sbjct: 253 RLEEILSIVMRGVFQS---AGQNCIGIERIIALDGVYDTIITKLYNRISTMRLGMYTQND 309
Query: 302 TEYTHMIHERAYNRIQTVIE--TTKGQKTV-----AQHSDNLPPLCIPPTIISDVSWDDP 354
+ M+ ++ ++++I+ +KG + V QH PT++ D + +
Sbjct: 310 VDMGAMVSNNRFDHLESLIQDAVSKGARLVYGGHRFQHPKYPKGNYFLPTLLVDATNEMK 369
Query: 355 SMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVV 414
E F PI + R + ++ + + L +F K + + +G V
Sbjct: 370 IAQEECFAPIALVFRAKSPEHALE-IANGTEFGLGASVFGRDKQLCQYFTDNLETGMVAV 428
Query: 415 NDTLLHVGIEEAPFGGIGTSGYGNYHG 441
ND + + PFGG SGYG + G
Sbjct: 429 NDFGAFY-LLQMPFGGCKKSGYGRFAG 454
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 112 bits (280), Expect = 1e-24
Identities = 101/356 (28%), Positives = 164/356 (45%), Gaps = 31/356 (8%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA- 176
+ ++ +G V I +N+PI A A+A GN+V++KPS L+P A ++ EI A
Sbjct: 335 YTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTALILAEILKSAG 394
Query: 177 FEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAA-KSLTPCVLELGGKS 235
G +QG AE L+ K+ +TGS G I + A +++ P LELGGKS
Sbjct: 395 LPDGVFNVIQGDAETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIKPVTLELGGKS 454
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEF----VDSCKKVL 291
+ + + ++A+ ++ + GQ+C A VL S+ EF VD +K+
Sbjct: 455 ALIV---FDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVDHTQKM- 510
Query: 292 NEFYPSVTSDTEYTHMIHERAYNRIQTVIET------TK--GQKTVAQHS-DNLPPLCIP 342
+ + DT+ I N+++ I T TK G VA H +N +
Sbjct: 511 -KIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGLEN--GFYLS 567
Query: 343 PTIISDVSWDDPSMT---GENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDE 399
P I++ ++ P MT E FG +L I+ + DE I + D L + T
Sbjct: 568 PCILTGIT---PKMTVYREEIFGSVLLIIPFDTEDEAI-KIANDTDMGLAAGLVTKDLSR 623
Query: 400 IDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIF 455
+ ++ +G VN T V PFGG+G SG+G +G + +TH +++F
Sbjct: 624 SYRVSEQLNAGNVYVN-TYNDVS-PLVPFGGVGESGFGRENGTAVLEHYTHLKSVF 677
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 112 bits (280), Expect = 1e-24
Identities = 98/343 (28%), Positives = 161/343 (46%), Gaps = 28/343 (8%)
Query: 103 KKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELT 162
+K VSL F ++V K LG V +I+P+N+P+L+A+ +A ++A G + + KPSEL
Sbjct: 138 QKAPVSLPMESF-KSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGCTAILKPSELA 196
Query: 163 PACAEVMEEICNE-AFEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKA 220
+ +IC E G + + G G+E + L DKI +TGS G+ + A
Sbjct: 197 SVTCLELADICREVGLPPGVLNVLTGFGSEAGAPLASHPGVDKIAFTGSFATGSKVMTAA 256
Query: 221 AKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIY 280
A+ + P +ELGGKSP+ + ++ + A + GQIC A +L +SI
Sbjct: 257 AQLVKPVSMELGGKSPLIVFDDV---DLDKAAEWALFGCFWTNGQICSATSRLLVHESIA 313
Query: 281 DEFVDSCKKVLNEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPPLC 340
EF++ K + + + + + E R+ V+ +KG QH +
Sbjct: 314 SEFIEKLVK--------WSKNIKISDPMEEGC--RLGPVV--SKG-----QHLEK--GFF 354
Query: 341 IPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEI 400
I PTII+DV+ E FGP+L + + DE I+ L L + +N +
Sbjct: 355 IEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIE-LANDSHYGLGAAVISNDTERC 413
Query: 401 DHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPY 443
D I +G +N + +AP+GG+ SG+G G +
Sbjct: 414 DRISEAFEAGIVWINCS--QPCFTQAPWGGVKRSGFGRELGEW 454
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 112 bits (279), Expect = 2e-24
Identities = 83/337 (24%), Positives = 149/337 (43%), Gaps = 16/337 (4%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVE 183
+G V +I+P+NFP + A A++ G S V KPS TP A + + EA V
Sbjct: 155 IGVVALIAPWNFPTAMIARKAAAALSVGCSAVVKPSGDTPLSALALAQTAEEAGIPAGVF 214
Query: 184 TV-----QGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVF 238
V AE + L ES I +TGST VG ++ ++A ++ LELGG +P+
Sbjct: 215 NVITADHSNTAEISKYLCESTDVSAISFTGSTPVGKLLLAQSASTVKRVCLELGGNAPLI 274
Query: 239 ISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNE---FY 295
+ + + A+ + +GQ CV+A+ + + I+D+++ + E
Sbjct: 275 V---FDDADLDVAVNGTMATKFRCSGQTCVSANRIYVHEKIHDQYISKLAAAMKEKLVLG 331
Query: 296 PSVTSDTEYTHMIHERAYNRIQTVIETT--KGQKTVAQHSDNLPPLCIPPTIISDVSWDD 353
+ T +++++A ++ + ++ KG + + PT+I++V +
Sbjct: 332 DGLNPKTTQGPLVNQKAVDKCELLLSDALGKGSELICGGKRGEHGTSYEPTLITNVQSNT 391
Query: 354 PSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACV 413
E FGPI + ++ D E ++ L Y+F + + + ++ G
Sbjct: 392 NIAHTEIFGPIASVQKFRDEQEVLEA-ANNCRVGLAGYVFGRDQSRLQRVARKLEVGMVG 450
Query: 414 VNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTH 450
VN+ L + EA FGG+ SG G G FT+
Sbjct: 451 VNEGL--ISCAEAAFGGVKESGIGREGGAQGIDEFTN 485
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 110 bits (275), Expect = 5e-24
Identities = 98/349 (28%), Positives = 160/349 (45%), Gaps = 18/349 (5%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
T K +G +I P+N+P+++ A +A GN+VV KP+++TP A E+ +A
Sbjct: 557 TLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKA 616
Query: 177 -FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCV-LELGG 233
KG V + G G+ L + KI +TGST VG I + A S V LELGG
Sbjct: 617 GIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGG 676
Query: 234 KSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNE 293
KSP+ I + ++ A++ S N G+ C+AA + DSI+DEFV + + +
Sbjct: 677 KSPLIIFADCDLNK---AVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRK 733
Query: 294 FYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQ-----HSDNLPPLCIPPTIISD 348
D + H + ++ + G K A + P PT+ +D
Sbjct: 734 MKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTD 793
Query: 349 VSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP---LVQYIFTNSKDEIDHILT 405
V E+FGP++ I R+ D D +D ++ R + L +FT ++ ++
Sbjct: 794 VEDHMFIAKEESFGPVMIISRFADGD--LDAVLSRANATEFGLASGVFTRDINKALYVSD 851
Query: 406 RIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
++++G VN T + APFGG SG+G G + +T+
Sbjct: 852 KLQAGTVFVN-TYNKTDV-AAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 110 bits (274), Expect = 7e-24
Identities = 92/347 (26%), Positives = 150/347 (42%), Gaps = 16/347 (4%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA- 176
F + +G +I P+NFP + A A+A G +VV KP TP A M + +A
Sbjct: 148 FTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAG 207
Query: 177 FEKGQVETVQGGAEETS---ALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGG 233
F KG + A L ES K K+ +TGST VG I+ ++++ +L ELGG
Sbjct: 208 FPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQSSSTLKKLSFELGG 267
Query: 234 KSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNE 293
+P + + Q A+ + GQ CV A+ + SI D+F + + +
Sbjct: 268 NAPFIVFEDADLDQ---ALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKLLAERVKK 324
Query: 294 FYPSVTSDTEYTH--MIHERAYNRIQTVIETT--KGQKTVAQ--HSDNLPPLCIPPTIIS 347
F D + TH +I+ A +++ + KG K V + L P P I+S
Sbjct: 325 FVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPNFYAPVILS 384
Query: 348 DVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRI 407
V E FGP+ PI + ++E + + L Y+F+ + + + + +
Sbjct: 385 HVPSTAIVSKEETFGPLCPIFSFDTMEEVVG-YANDTEFGLAAYVFSKNVNTLYTVSEAL 443
Query: 408 RSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+G N + PFGG+ SG+G Y + +T +TI
Sbjct: 444 ETGMVSCNTGVF--SDCSIPFGGVKESGFGREGSLYGIEDYTVLKTI 488
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 109 bits (273), Expect = 9e-24
Identities = 97/350 (27%), Positives = 149/350 (41%), Gaps = 22/350 (6%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
+ K +G V I P+N+P+L+ A+A G +++ KP+E TP A M + EA
Sbjct: 315 SMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEA 374
Query: 177 -FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGG 233
F G + V G G +A+ K+ +TGS +G I+ + AA S L LELGG
Sbjct: 375 GFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGG 434
Query: 234 KSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFV------DSC 287
KSPV + + + A+ + + N GQ C A + IYDEFV
Sbjct: 435 KSPVVV---FDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKA 491
Query: 288 KKVLNEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNL---PPLCIPPT 344
+KV N F +V + I + ++ IE+ K + Q + PT
Sbjct: 492 RKVGNPFEQNVQQGPQ----IDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPT 547
Query: 345 IISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHIL 404
+ SDV D E FGP+ I +++ L+E ID L + TN ++
Sbjct: 548 VFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDR-ANNVQYGLAAGVITNDINKALKFA 606
Query: 405 TRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+ +G+ +N + PFGG SG G G + +TI
Sbjct: 607 NNVDAGSVWIN--CYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTI 654
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 108 bits (271), Expect = 1e-23
Identities = 101/334 (30%), Positives = 148/334 (44%), Gaps = 25/334 (7%)
Query: 118 FVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEV-MEEICNEA 176
+V+ +G +ISP+N P+ L LA A+ GN+VV KPSE+T A V M
Sbjct: 159 YVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEMTSVTAWVLMHAFKLVG 218
Query: 177 FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
F G V V G G LV+ I +TGST +G I E AK LE+GGK+
Sbjct: 219 FPPGVVNMVIGEGKSAGQRLVDHVDVPLISFTGSTVIGKKIQEDGAKLNKKVSLEMGGKN 278
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEF- 294
P + N KS I I SS N G+IC+ + I+ +FV S + +F
Sbjct: 279 PGIVYSNYRKSD----IASIARSSFLNQGEICLCTSRLFVQKPIFADFVKSYVEEAKKFT 334
Query: 295 YPSVTSDTEYTHMIHERAYNRIQTVIETTK---------GQKTVAQHSDNLPPLCIPPTI 345
T+ + M + Y ++++ IE K G T+ +N I PT+
Sbjct: 335 VGDPTTQVQIGAMNSKVHYEKVKSYIELAKKEGADILCGGVTTIQNGCEN--GYFITPTV 392
Query: 346 ISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP--LVQYIFTNSKDEIDHI 403
I + MT E FGP++ I + +E I+ + TP L ++++ DE+ +
Sbjct: 393 IVGLHDASKVMTDEIFGPVVCITPFDTAEEVIE---RANSTPYGLSATVWSSDSDELLNT 449
Query: 404 LTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYG 437
+R+G N L PFGG SG G
Sbjct: 450 ANELRAGTVWCNTWLAR--DLSMPFGGCKQSGNG 481
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 108 bits (269), Expect = 3e-23
Identities = 86/330 (26%), Positives = 145/330 (43%), Gaps = 15/330 (4%)
Query: 121 KIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEK 179
K +G +I+P+NFP + A+A G + +F P+ TP + + EA F
Sbjct: 152 KQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVCLGLVRLAQEAGFPD 211
Query: 180 G--QVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPV 237
G V T + L + K+ +TGST VG I+ ++A ++ +ELGG +P
Sbjct: 212 GVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSASTIKKVSMELGGNAPF 271
Query: 238 FISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLN--EFY 295
+ P+ P Q A+ + GQ+CV + V ++YDEFV + + +
Sbjct: 272 IVFPDFPIDQ---AVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVSKLTEKVKTIKVG 328
Query: 296 PSVTSDTEYTHMIHERAYNRIQTVIE--TTKGQKTV--AQHSDNLPPLCIPPTIISDVSW 351
S + +I + ++ IE +KG K + + PT++S V+
Sbjct: 329 DGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISSSKGYFFEPTVLSGVTQ 388
Query: 352 DDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGA 411
D + E FGP+ + ++ D +E I+ D L Y+FTN+ + H+ + G
Sbjct: 389 DMLVASEETFGPLASVFKFDDTEEVIE-WANDSDVGLAGYVFTNNLSTMIHVAKELEVG- 446
Query: 412 CVVNDTLLHVGIEEAPFGGIGTSGYGNYHG 441
+V + V FGGI SG+G G
Sbjct: 447 -LVGANIEMVDEPFISFGGIKQSGFGKEAG 475
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 106 bits (265), Expect = 7e-23
Identities = 101/433 (23%), Positives = 189/433 (43%), Gaps = 39/433 (9%)
Query: 39 TDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIKNMKK 98
+D + R+R L L+ + +N++ + A +D + + E++ I + IK+ ++
Sbjct: 151 SDFSRRLRVLASLHDYILNNQDLIARVACRDSGKTMLDASMGEILVTLEKIQWTIKHGQR 210
Query: 99 EIEPKKIK--VSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVF 156
++P + + W+ + LG + I +N+P L P+ A+ GN++V
Sbjct: 211 ALQPSRRPGPTNFFMKWYKGAEIRYEPLGVISSIVSWNYPFHNLLGPIIAALFTGNAIVV 270
Query: 157 KPSELTPACAEVMEEI---CNEAFEKGQVETVQ--------GGAEETSALVESGKFDKIF 205
K SE +E E+ C EA ++ + VQ + + F I
Sbjct: 271 KCSEQVVWSSEFFVELIRKCLEACDEDP-DLVQLCYCLPPTENDDSANYFTSHPGFKHIT 329
Query: 206 YTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQ 265
+ GS V I + AAKSLTP V+ELGGK + + ++I I + ++GQ
Sbjct: 330 FIGSQPVAHYILKCAAKSLTPVVVELGGKDAFIVLDSAKNLDALSSI--IMRGTFQSSGQ 387
Query: 266 ICVAADYVLCPDSIYDEFVDSCKKVLNEFYPS--VTSDTEYTH--------MIHERAYNR 315
C+ + V+ YD+ V K+LN+ + + ++ H MI + ++
Sbjct: 388 NCIGIERVIVSKENYDDLV----KILNDRMTANPLRQGSDIDHLENVDMGAMISDNRFDE 443
Query: 316 IQTVIE--TTKGQKTVA-----QHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILPIM 368
++ +++ KG + + +H PT++ DV+ + E FGPIL +M
Sbjct: 444 LEALVKDAVAKGARLLQGGSRFKHPKYPQGHYFQPTLLVDVTPEMKIAQNEVFGPILVMM 503
Query: 369 RYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPF 428
+ + D + L L +F E +++ +++G +ND + + PF
Sbjct: 504 KAKNTDHCVQ-LANSAPFGLGGSVFGADIKECNYVANSLQTGNVAINDFATFY-VCQLPF 561
Query: 429 GGIGTSGYGNYHG 441
GGI SGYG + G
Sbjct: 562 GGINGSGYGKFGG 574
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 106 bits (265), Expect = 7e-23
Identities = 97/351 (27%), Positives = 162/351 (45%), Gaps = 22/351 (6%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
T K +G +I P+N+P+++ A +A GN+VV KP+++TP A E+ +A
Sbjct: 557 TLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKA 616
Query: 177 -FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCV-LELGG 233
KG V + G G+ L + KI +TGST VG I + A S V LELGG
Sbjct: 617 GIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGG 676
Query: 234 KSP--VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVL 291
+SP +F +L K+ + + +++S G+ C+AA + DSI+DEFV + +
Sbjct: 677 ESPFIIFADCDLNKAV-QMGMSSVFFSK----GENCIAAGRLFVEDSIHDEFVRRVVEEV 731
Query: 292 NEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQ-----HSDNLPPLCIPPTII 346
+ D + H + ++ + G K A + P PT+
Sbjct: 732 RKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVF 791
Query: 347 SDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP---LVQYIFTNSKDEIDHI 403
+DV E+FGP++ I R+ D D +D ++ R + L +FT ++ ++
Sbjct: 792 TDVEDHMFIAKEESFGPVMIISRFADGD--LDAVLSRANATEFGLASGVFTRDINKALYV 849
Query: 404 LTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
++++G VN T + APFGG SG+G G + +T+
Sbjct: 850 SDKLQAGTVFVN-TYNKTDV-AAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 106 bits (265), Expect = 7e-23
Identities = 96/349 (27%), Positives = 158/349 (44%), Gaps = 30/349 (8%)
Query: 125 GTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVE 183
G V I +N+P + +A A+A GN+VV+KPS PA ++ EI A KG
Sbjct: 227 GVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPASPVLLGEILTAAGVPKGVYN 286
Query: 184 TVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAA-KSLTPCVLELGGKSPVFISPN 242
+QG E AL E K+ +TGS G + +AA K++ P LELGGKS + I
Sbjct: 287 VIQGEQEAGVALCEHNLVAKVSFTGSVASGEAVQRQAATKNVKPVTLELGGKSEIII--- 343
Query: 243 LPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNE---FYPSVT 299
S ++A+ ++ N GQ+C A V I F ++ + N+ +
Sbjct: 344 FDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTEAIVQEANDKLKVGDPLL 403
Query: 300 SDTEYTHMIHERAYNRIQTVIETTKGQ-KTVAQHSDNLPPLCI------PPTIISDVSWD 352
DT I+E RI +E+ K + V + + P + P II+ +S +
Sbjct: 404 EDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRVHPTGVEGGAYFEPAIITGLSDE 463
Query: 353 DPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP---LVQYIFTNSKDEIDHILTRIRS 409
++ E FG ++ I+ + ET + +I R + L +F+ + + R+++
Sbjct: 464 ARAVREEIFGAVMLILPF----ETEEEVIARANNTTYGLAAGVFSGNLARGHRVAARLQA 519
Query: 410 GACVV---NDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTIF 455
G + NDT ++V PFGG SG+G + T + T + I+
Sbjct: 520 GTVFINTYNDTEVNV-----PFGGFKNSGHGRENCIDTLRAHTQTKAIY 563
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 105 bits (262), Expect = 2e-22
Identities = 111/432 (25%), Positives = 189/432 (43%), Gaps = 17/432 (3%)
Query: 15 KIELAKQFYRSRQARLAQS--KSPRATDINERIRSLQKLYWAVKDNEERLIAAASKDFHR 72
K++ Q + LA+S KS T + +R L K +KDN+ + + K+ +
Sbjct: 46 KVQACTQEEVNAVMELAKSAQKSWAKTPLWKRAELLHKAAAILKDNKAPMAESLVKEIAK 105
Query: 73 ARSETLTIELVPLYNNILYLIKNMKKEIEPKKIKVSLLAHWFGTT---FVEKIALGTVLV 129
+++T E+V + I Y + + + K +S T KI LG VL
Sbjct: 106 PAKDSVT-EVVRSGDLISYCAEEGVRILGEGKFLLSDSFPGNDRTKYCLTSKIPLGVVLA 164
Query: 130 ISPFNFPILLALDPLAGAIAGGNSVVFK-PSELTPACAEVMEEICNEAFEKGQVETVQG- 187
I PFN+P+ LA+ +A A+ GNS+V K P++ +C ++ F KG + + G
Sbjct: 165 IPPFNYPVNLAVSKIAPALIAGNSLVLKPPTQGAVSCLHMVHCFHLAGFPKGLISCITGK 224
Query: 188 GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFISPNLPKSQ 247
G+E L + I +TG T G I++KA + P +ELGGK + L +
Sbjct: 225 GSEIGDFLTMHPAVNCISFTGGDT-GISISKKA--GMIPLQMELGGKDACIV---LDDAD 278
Query: 248 WETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCK-KVLNEFYPSVTSDTEYTH 306
+ I +GQ C A VL +S+ DE V+ K KV +++ T
Sbjct: 279 LDLVASNIIKGGFSYSGQRCTAVKVVLVMESVADELVEKVKAKVAKLTVGPPEENSDITA 338
Query: 307 MIHERAYNRIQTVIETTKGQKTVAQHSDNLPPLCIPPTIISDVSWDDPSMTGENFGPILP 366
++ E + N I+ ++ K + I P ++ +V D E FGP++P
Sbjct: 339 VVSESSANFIEGLVMDAKEKGATFCQEYKREGNLIWPLLLDNVRPDMRIAWEEPFGPVVP 398
Query: 367 IMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEA 426
++R ++E I+ + L +FT ++ I + +G +N G +
Sbjct: 399 VLRINSVEEGINH-CNASNFGLQGCVFTKDINKAILISDAMETGTVQINSAPAR-GPDHF 456
Query: 427 PFGGIGTSGYGN 438
PF G+ SG G+
Sbjct: 457 PFQGLKDSGIGS 468
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 104 bits (259), Expect = 4e-22
Identities = 86/347 (24%), Positives = 156/347 (44%), Gaps = 25/347 (7%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVE 183
LG V VIS FNFP + A A+ GNSVV+KP+ TP A + ++ E V
Sbjct: 158 LGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLVEEVLVANNVN 217
Query: 184 T-----VQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVF 238
V G + ALV+ + + + +TGS+ +G I+ ++ +LELGG + +
Sbjct: 218 PALCSLVCGEGDVGQALVKDKRVNLVSFTGSSEIGKIVGQQVQARFGKLLLELGGNNAII 277
Query: 239 ISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYPSV 298
++ + + + ++++G AGQ C ++ D +YD+ ++ KK +F +
Sbjct: 278 VNED---ADLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLERLKKAYAQFESRI 334
Query: 299 ----TSDTEYTHMIHERAYNRIQTVI--ETTKGQK-----TVAQHSDNLPPLCIPPTIIS 347
S+T + +++A + + + G K V + N + PTI++
Sbjct: 335 GCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGKIEYGGKVLERDGNF----VLPTIVT 390
Query: 348 DVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRI 407
+ D P + E F PIL +++++ L+E I + D L +FT + + +
Sbjct: 391 GLKHDSPVVLRETFAPILYVLKFSTLEEAI-AINNEVDQGLSSSLFTTNIQNVFKWMGPK 449
Query: 408 RSGACVVNDTLLHVGIE-EAPFGGIGTSGYGNYHGPYTFKTFTHERT 453
S +VN + G E FGG +G G G +++ + T
Sbjct: 450 GSDCGIVNVNIPTSGAEIGGAFGGEKETGGGRESGSDSWRQYMRRST 496
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 103 bits (257), Expect = 6e-22
Identities = 91/348 (26%), Positives = 155/348 (44%), Gaps = 31/348 (8%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNE-AFEKGQV 182
+G I P+NFPI++ +A A+A GN + KP+ +TP A +C + G V
Sbjct: 163 IGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVV 222
Query: 183 ETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGGKSP--VF 238
V G G +AL + K+ +TGST VG +A +++S L LELGGKS VF
Sbjct: 223 NIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVF 282
Query: 239 ISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLN------ 292
N+ K+ + + NAGQIC + + + IYDE + + K L
Sbjct: 283 DDANIKKT-----LPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVG 337
Query: 293 ------EFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPPLCIPPTII 346
F ++T+ ++ +++ + + T G+K + I PT+
Sbjct: 338 NPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDK------GYFIRPTVF 391
Query: 347 SDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTR 406
DV+ D + E FGP++ + ++ L+E ++ + + L I T S +
Sbjct: 392 YDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVE-MANSSEFGLGSGIETESLSTGLKVAKM 450
Query: 407 IRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+++G +N + PFGG+ SGYG G + +T + +
Sbjct: 451 LKAGTVWIN--TYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAV 496
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 97.1 bits (240), Expect = 6e-20
Identities = 106/427 (24%), Positives = 178/427 (40%), Gaps = 36/427 (8%)
Query: 37 RATDINERIRSLQKLYWAVKDNEERLIAAASKDFHRARSETLTIELVPLYNNILYLIKNM 96
R ER + L KL +++++E L S D + L V + ++
Sbjct: 484 RQMSARERGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTH-VGMSIDVWRYFAGW 542
Query: 97 KKEIEPKKIKVSLLAHWFGTTFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVF 156
+I+ K I +S + +G V +I+P+N+P+++ +A +A +
Sbjct: 543 CDKIQGKTIPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKMAACLAAAKIKLI 602
Query: 157 KPSELTPACAEVMEEICNEAFEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTI 215
+ S G + V G G+ + L KI +TGST +G
Sbjct: 603 EIS--------------------GVINIVTGSGSLVGNRLTAHPDVRKIGFTGSTEIGAT 642
Query: 216 IAEKAAKS-LTPCVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVL 274
+ E AKS + LELGGKSP+ I + + E A+++ + N G+ C+AA V
Sbjct: 643 VMESCAKSNIKKVSLELGGKSPLIIFAD---ADLEKAVKQACGAVFFNKGENCIAAGRVF 699
Query: 275 CPDSIYDEFVDSCKKVLNEFYPSVTSDTEYTH--MIHERAYNRIQTVIE-TTKGQKTVAQ 331
SI+D+FV + ++ D H H N++ +E G V
Sbjct: 700 IAKSIHDDFVKKLVEEAKQYQIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAGGAKVEV 759
Query: 332 HSDNLPP--LCIPPTIISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTP-- 387
L L PPTI+S++ ++ + + E+FGPI+ + + D D+ D L + DT
Sbjct: 760 GGKRLEREGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDD-DDIEDVLRRANDTEFG 818
Query: 388 LVQYIFTNSKDEIDHILTRIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTFKT 447
L +FT + + + +G VN T + APFGG SG+G G
Sbjct: 819 LAAGVFTRDSSKSLRVAEALHAGTVFVN-TYQKTDV-AAPFGGFKQSGFGKDMGEEALNE 876
Query: 448 FTHERTI 454
+ +TI
Sbjct: 877 YLVTKTI 883
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 88.6 bits (218), Expect = 2e-17
Identities = 59/188 (31%), Positives = 95/188 (50%), Gaps = 9/188 (4%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
TF K +G +I+P+N+P+++ +A IA GN+ + KP++ P A E+ A
Sbjct: 563 TFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRA 622
Query: 177 -FEKGQVETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKS-LTPCVLELGG 233
F G + + G G++ A+ + K+ +TGST +G I + A S L C LELGG
Sbjct: 623 GFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGG 682
Query: 234 KSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNE 293
KSP+ I + A++ S N G+ C+AA + D I+DEF+ ++VL +
Sbjct: 683 KSPLII---FADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFI---RRVLKD 736
Query: 294 FYPSVTSD 301
D
Sbjct: 737 LRTMTIGD 744
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 88.2 bits (217), Expect = 3e-17
Identities = 88/351 (25%), Positives = 154/351 (43%), Gaps = 20/351 (5%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
T+ + LG ++PFNFP ++ L AI GN+++ KPSE P ++ E+ NEA
Sbjct: 187 TYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEA 246
Query: 177 -FEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
G V + G + + + ++ + + + GS G I E+A K+ +G K+
Sbjct: 247 GCPPGVVNVIHGQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRVQSNMGAKN 306
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVA---ADYVLCPDSIYDEFVDSCKKVLN 292
I L + E + ++ ++ G AGQ C+A A +V + + V+ +K+
Sbjct: 307 HGII---LGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDAQAWIPDLVERAQKL-- 361
Query: 293 EFYPSVTSDTEYTHMIHERAYNRIQTVIET--TKGQKTVAQHSDNLPP-----LCIPPTI 345
+ T+ +I + RI +IE+ +G K + P + PTI
Sbjct: 362 KVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDGYFVGPTI 421
Query: 346 ISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILT 405
+SDV+ T E FGP+L I++ LD+ I ++ +FT + +
Sbjct: 422 LSDVTPSMKCYTEEIFGPVLVILKADTLDDAIG-IVNANPYGNGTAVFTTNGAAARKFVN 480
Query: 406 RIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYH--GPYTFKTFTHERTI 454
I +G VN + V + F G S G++H G K +T +T+
Sbjct: 481 EIDAGQVGVN-VPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTV 530
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 87.4 bits (215), Expect = 5e-17
Identities = 94/360 (26%), Positives = 154/360 (42%), Gaps = 22/360 (6%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
T+ + LG I PFNFP ++ L A+ GN+ + KPSE P + ++ E+ EA
Sbjct: 243 TYSIREPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFILKPSEKDPGASVILAELAMEA 302
Query: 177 -FEKGQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKS 235
G + V G + +A+ + + + GS T G I +AA +G K+
Sbjct: 303 GLPDGVLNIVHGTNDTVNAICDDEDIRAVSFVGSNTAGMHIYARAAAKGKRIQSNMGAKN 362
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLC---PDSIYDEFVDSCKKVLN 292
+ LP + + + + + G AGQ C+A V+ S D+ V+ K +
Sbjct: 363 HGLV---LPDANIDATLNALLAAGFGAAGQRCMALSTVVFVGDAKSWEDKLVERAKAL-- 417
Query: 293 EFYPSVTSDTEYTHMIHERAYNRIQTVIET--TKGQKTVAQHSDNLPP-----LCIPPTI 345
+ D + +I ++A RI +I++ G K + D + P I PTI
Sbjct: 418 KVTCGSEPDADLGPVISKQAKERICRLIQSGVDDGAKLLLDGRDIVVPGYEKGNFIGPTI 477
Query: 346 ISDVSWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILT 405
+S V+ D E FGP+L M+ DE I ++I + IFT+S
Sbjct: 478 LSGVTPDMECYKEEIFGPVLVCMQANSFDEAI-SIINKNKYGNGAAIFTSSGAAARKFQM 536
Query: 406 RIRSGACVVNDTLLHVGIEEAPFGGIGTSGYG--NYHGPYTFKTFTHERTIFKQPFWVDL 463
I +G +N + V + F G S G N++G FT +T+ +Q W D+
Sbjct: 537 DIEAGQIGIN-VPIPVPLPFFSFTGNKASFAGDLNFYGKAGVDFFTQIKTVTQQ--WKDI 593
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 87.4 bits (215), Expect = 5e-17
Identities = 84/342 (24%), Positives = 149/342 (43%), Gaps = 18/342 (5%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEK---- 179
LG V VI+ FNFP + A+ GN VV+K + TP M ++ E EK
Sbjct: 155 LGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLVAEVLEKNNLP 214
Query: 180 GQVETVQ-GGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVF 238
G + T GGAE A+ + + + +TGS+ VG+++ + +LEL G + +
Sbjct: 215 GAIFTAMCGGAEIGEAIAKDTRIPLVSFTGSSRVGSMVQQTVNARSGKTLLELSGNNAII 274
Query: 239 ISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSC------KKVLN 292
+ + + + A R + ++++G AGQ C +L +S+YD+ ++ K+ N
Sbjct: 275 V---MDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVLEQLLTSYKQVKIGN 331
Query: 293 EFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNLPPLCIPPTIISDVSWD 352
+T + I+ VI++ G+ + + PTII ++S D
Sbjct: 332 PLEKGTLLGPLHTPESKKNFEKGIE-VIKSQGGKILTGGKAVEGEGNFVEPTII-EISAD 389
Query: 353 DPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGAC 412
+ E F P+L ++++ E + + L IFT + + I + + S
Sbjct: 390 AAVVKEELFAPVLYVLKFKSFGEAV-AINNSVPQGLSSSIFTRNPENIFRWIGPLGSDCG 448
Query: 413 VVNDTLLHVGIE-EAPFGGIGTSGYGNYHGPYTFKTFTHERT 453
+VN + G E FGG +G G G ++K + T
Sbjct: 449 IVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRRST 490
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 84.3 bits (207), Expect = 4e-16
Identities = 99/374 (26%), Positives = 156/374 (41%), Gaps = 45/374 (12%)
Query: 125 GTVLVISPFNFPILLALDPLAGAIA-GGNSVVFKPSELTPACAEVMEEICNEA-FEKGQV 182
G V +SPFNF + A L GA A GN+VV+KPS+ ++ + EA KG +
Sbjct: 203 GFVYAVSPFNFTAIAA--NLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVI 260
Query: 183 ETVQGGAEETSALVESGK-FDKIFYTGSTTV-----GTI---IAEKAAKSLTPCVLELGG 233
+ G + + V + K F + +TGST V G I + E + + E GG
Sbjct: 261 NFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGG 320
Query: 234 KSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNE 293
K+ + P+ S A+ + GQ C AA + P+S +EF+ +L
Sbjct: 321 KNFHLVHPSANISH---AVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQS 377
Query: 294 --FYPSVTSDTEYTH---------MIHERAYNRIQTVIETTKGQKTV----AQHSDNLPP 338
P TS + + +IHE++++++ VIE K + D
Sbjct: 378 QNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQG 437
Query: 339 LCIPPTIISDVSWDDPSMTGENFGPILPIMRY--TDLDETIDTLIKRFDTPLVQYIFTNS 396
+ PT+I D P M+ E FGPIL + Y T+ +E D + L IF
Sbjct: 438 WFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKD 497
Query: 397 KDEIDHILTRIR--SGACVVNDTLLHVGIEEAPFGGIGTSGYGN-YHGPYTFKTFT---- 449
+ I++ +++ +G +ND + + FGG SG + GP F
Sbjct: 498 RKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRN 557
Query: 450 -----HERTIFKQP 458
+E T FK P
Sbjct: 558 TKENFYELTDFKYP 571
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 83.2 bits (204), Expect = 9e-16
Identities = 78/343 (22%), Positives = 144/343 (41%), Gaps = 16/343 (4%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVE 183
LG V VIS +NFP + A A+ GNSV++K + TP + +I E + +
Sbjct: 237 LGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLP 296
Query: 184 TV----QGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFI 239
V QGG + LV + + + +TGS G + + + +LELGG + + I
Sbjct: 297 PVVTLCQGGTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALII 356
Query: 240 SPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSC----KKVLNEFY 295
+ + + A+ + +G +GQ C ++ + ++D+FV K+++++
Sbjct: 357 DES---ANVKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIG 413
Query: 296 PSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNL---PPLCIPPTIISDVSWD 352
+ + T + ++ + I K N+ + PT+I+ + D
Sbjct: 414 HQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHD 473
Query: 353 DPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRSGAC 412
+ E F PI+ I++ ++D+ I+ + L IFT + + + S
Sbjct: 474 ASVVHRETFAPIVYILKAKNVDQAIE-WNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCG 532
Query: 413 VVNDTLLHVGIE-EAPFGGIGTSGYGNYHGPYTFKTFTHERTI 454
+VN G E FGG +G G G +K + TI
Sbjct: 533 IVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATI 575
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 82.8 bits (203), Expect = 1e-15
Identities = 71/271 (26%), Positives = 122/271 (44%), Gaps = 16/271 (5%)
Query: 121 KIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEK 179
+I LG I PFNFP ++ L A+A GN++V KPSE P A+++ E+ EA
Sbjct: 163 RIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEAGVPD 222
Query: 180 GQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFI 239
G V + G + + ++ I + G G I E+ AK+ +G K+ I
Sbjct: 223 GCVNIIHGQHSAVNFICDNPDIKAISFVGGDAAGKHIYERGAKNGKRVQSNMGAKNHGVI 282
Query: 240 SPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSI---YDEFVDSCKKVLNEFYP 296
+ K Q + ++ ++ G AGQ C+A + E V+ K + +
Sbjct: 283 MADANKEQ---TLNQLTAAAFGAAGQRCMALTTAVLVGEARAWLPELVEKAKNL--KVNA 337
Query: 297 SVTSDTEYTHMIHERAYNRIQTVIETTK--GQKTVAQHSDNLPP-----LCIPPTIISDV 349
DT+ +I +++ R+ +IE+ K G + S+ P + PTI++ V
Sbjct: 338 GWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGNFVGPTILAGV 397
Query: 350 SWDDPSMTGENFGPILPIMRYTDLDETIDTL 380
+ E FGP+L +M +L+E I+ +
Sbjct: 398 KPNMTCYREEIFGPVLVVMEAENLNEAIEII 428
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 77.4 bits (189), Expect = 5e-14
Identities = 82/345 (23%), Positives = 145/345 (41%), Gaps = 23/345 (6%)
Query: 124 LGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQV- 182
+G V +I+ FNFP+ + A A+ GN ++K + T + + +I + E ++
Sbjct: 157 VGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLP 216
Query: 183 ----ETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVF 238
GGA+ +A+ + + + + +TGST VG + + +LELGG + +
Sbjct: 217 GAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAII 276
Query: 239 ISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKK------VLN 292
+ S + ++++G AGQ C A + +SI+DE V+ KK V N
Sbjct: 277 AFEDADLS---LVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGN 333
Query: 293 EFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHSDNL---PPLCIPPTIISDV 349
+ P+V Y + ++A + +E K + + + P + PTI++ +
Sbjct: 334 PWDPNVL----YGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGL 389
Query: 350 SWDDPSMTGENFGPILPIMRYTDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRIRS 409
D E F PIL + ++ + +E + L IFT I L S
Sbjct: 390 GHDASIAHTETFAPILYVFKFKN-EEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGS 448
Query: 410 GACVVNDTLLHVGIE-EAPFGGIGTSGYGNYHGPYTFKTFTHERT 453
+VN + G E FGG +G G G +K + T
Sbjct: 449 DCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRST 493
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 75.1 bits (183), Expect = 2e-13
Identities = 84/366 (22%), Positives = 153/366 (40%), Gaps = 29/366 (7%)
Query: 125 GTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVE 183
G V I+PFNF + A + A + GN V+ KPS+ + ++ +I EA G ++
Sbjct: 184 GFVYAITPFNFTAI-AGNLAAAPLLMGNVVLMKPSDHAVLSSYIVYQIFREAGLPAGALQ 242
Query: 184 TVQGGAEETSALV-ESGKFDKIFYTGST--------TVGTIIAEKAAKSLTPCVLELGGK 234
+ G A E S + +F + +TGST T+G +A ++ V E GGK
Sbjct: 243 FIPGDAVEVSKVCFNHPEFAGLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGK 302
Query: 235 SPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDE-FVDSCKKVLNE 293
+ + + ++ ++A+ ++ GQ C A + ++ F D K +
Sbjct: 303 NFHLVHSS---AEIKSAVVNAVRAAFEYQGQKCSALSRLYVSKYAWENGFRDELTKQVKS 359
Query: 294 FYPSVTSDTEYTH----MIHERAYNRIQTVIETTKGQKTV----AQHSDNLPPLCIPPTI 345
T++ + +IH+ ++N+++ V+E+ + +D+ + PT+
Sbjct: 360 LKVGAPL-TDFANFVGPVIHQASFNKLKKVLESAASDSEIEVLAGGKADDSEGFFVEPTV 418
Query: 346 ISDVSWDDPSMTGENFGPILPIMRYTD--LDETIDTLIKRFDTPLVQYIFTNSKDEIDHI 403
+ + E FGP+L + Y D LD D + L IF + + +
Sbjct: 419 LLSKNPKHDIFVNELFGPVLSVYVYEDDNLDAVCDLIDTTTPYGLTGSIFAQDRVVVRKL 478
Query: 404 LTRIRSGA--CVVNDTLLHVGIEEAPFGGIGTSGYGNYHGP-YTFKTFTHERTIFKQPFW 460
R+R+ A +ND + E PFGG SG + G F R+I +
Sbjct: 479 TDRLRNAAGNFYINDKCTGAVVGEQPFGGARASGTNDKAGSGMILSRFVSPRSIKDTFAY 538
Query: 461 VDLLIY 466
D ++Y
Sbjct: 539 ADSVLY 544
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 69.7 bits (169), Expect = 1e-11
Identities = 65/268 (24%), Positives = 112/268 (41%), Gaps = 16/268 (5%)
Query: 121 KIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEK 179
++ LG I+PFNFP ++ L A+ GN+ + KPSE P ++ ++ ++
Sbjct: 173 RLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPD 232
Query: 180 GQVETVQGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVLELGGKSPVFI 239
G + + G E + + + I + GS G I E+ ++ +G K+ +
Sbjct: 233 GTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVV 292
Query: 240 SPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSI---YDEFVDSCK--KVLNEF 294
P+ K E + ++ ++ G AGQ C+A + E V+ K +V
Sbjct: 293 MPDANK---ENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGD 349
Query: 295 YPSVTSDTEYTHMIHERAYNRIQTVIE-----TTKGQKTVAQHSDNLPPLCIPPTIISDV 349
P T ER N I + + G+K + +N + PTIIS+V
Sbjct: 350 QPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYEN--GNFVGPTIISNV 407
Query: 350 SWDDPSMTGENFGPILPIMRYTDLDETI 377
+ E FGP+L ++ LDE I
Sbjct: 408 KPNMTCYKEEIFGPVLVVLETETLDEAI 435
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/363 (23%), Positives = 143/363 (38%), Gaps = 33/363 (9%)
Query: 125 GTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEAFEKGQVET 184
G V I+PFNF + P A A+ G N ++KPS ++ E+ EA + +
Sbjct: 202 GFVAAIAPFNFTAIGGNLPTAPALMG-NVSLWKPSNTAVLSNYIIYELLEEAGMPPGILS 260
Query: 185 V--QGGAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVL------ELGGKSP 236
G + S + +TGS I K A++L V E GGK+
Sbjct: 261 FLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTIWRKVAENLDNYVTFPKLIGECGGKNF 320
Query: 237 VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFYP 296
F+ P+ R S+ +GQ C A + P SI+ + ++ + E
Sbjct: 321 HFVHPSAHVDAVAAGTAR---SAWEYSGQKCSACSRMYAPKSIWPKILEKISAIHKEIKL 377
Query: 297 SVTSDTEY--THMIHERAYNRIQTVIETTK-----GQKTVAQHSDNLPPLCIPPTIISDV 349
D + +I ++A+ R++ I+ K + D+ I PT+I+
Sbjct: 378 GDVRDGSVFLSAVIDDKAFARLKAYIDFAKTGADGANVVLGGKCDDKTGYFIEPTLITVT 437
Query: 350 SWDDPSMTGENFGPILPIMRYTD--LDETIDTLIKRFDTPLVQYIFTNSKDEIDHILTRI 407
+T E FGP++ ++ Y D +DE + T+ L +F+ K+ + +
Sbjct: 438 DPKSKLLTEEMFGPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFSQDKEFLYRARDVL 497
Query: 408 RS--GACVVNDTLLHVGIEEAPFGGIGTSG---------YG-NYHGPYTFKTFTHERTIF 455
R G +ND + + PFGG SG YG + P T K + T +
Sbjct: 498 RDAVGNMYLNDKSTGSIVGQQPFGGSRLSGTNDKAGGPHYGLRWTSPLTIKETSVSLTDW 557
Query: 456 KQP 458
K P
Sbjct: 558 KYP 560
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 69.3 bits (168), Expect = 1e-11
Identities = 100/402 (24%), Positives = 177/402 (43%), Gaps = 39/402 (9%)
Query: 117 TFVEKIALGTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA 176
+F + G V ISPFNF + A A+ GNSV++KPS+ + + EA
Sbjct: 227 SFYNFLFAGFVAAISPFNFTGIAANLAYTPALM-GNSVIWKPSDSAILSNYFVFKALREA 285
Query: 177 -FEKGQVETVQGGAEET---SALVESGKFDKIFYTGSTTVGTIIAEKAAKSLT------P 226
G V V AEET S + + K I +TG++TV ++ + A+++
Sbjct: 286 GVPDGVVNFVP--AEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPR 343
Query: 227 CVLELGGKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDS 286
V E GGK+ F+ + ++ ETA+ ++ AGQ C + + P+S++ +
Sbjct: 344 LVGEGGGKNFHFVHSS---AEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHI-- 398
Query: 287 CKKVLNEFYPS--VTSDTEY-----THMIHERAYNRI----QTVIETTKGQKTVAQHSDN 335
++ L E S V D Y + +I+ RAY+RI + + ++ Q V D
Sbjct: 399 -REPLLEITASLVVRQDATYCDSFCSAVINRRAYDRIYMWLRYIDQSPSCQILVGGSCDK 457
Query: 336 LPPLCIPPTIISDVSWDDPSMTGENFGPILPIMRYTD--LDETIDTLIKRFDTPLVQYIF 393
+ PT++ D+ E PIL + Y D L ET++ + + + L +F
Sbjct: 458 RRGYYVDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEK-VAQINHGLTGSVF 516
Query: 394 TNSKDEIDHILT--RIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGNYHG-PYTFKTFTH 450
++ I+ R+ G VND + + + PFG +G + G P++ +T
Sbjct: 517 AQDQNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLGTPHSLLRWTS 576
Query: 451 ERTIFKQPFWVDLLIYVRYPPFDKLNTRISQISL--EDKPNF 490
+ I K+ + I+ Y + I+Q + +D+ +F
Sbjct: 577 PQVI-KESYKTHRNIFYPYMQINDQEQGIAQSDMVSQDESSF 617
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 61.6 bits (148), Expect = 3e-09
Identities = 84/354 (23%), Positives = 144/354 (39%), Gaps = 32/354 (9%)
Query: 125 GTVLVISPFNFPILLALDPLAGAIA-GGNSVVFKPSELTPACAEVMEEICNEA-FEKGQV 182
G V ISPFNF + LAGA A GN V++KPS+ + + I EA +
Sbjct: 202 GFVAAISPFNFTAIGG--NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNII 259
Query: 183 ETVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTP------CVLELGGKS 235
+ V G + S I +TGS + ++ A++L E GGK+
Sbjct: 260 QFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKN 319
Query: 236 PVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDSCKKVLNEFY 295
F+ + + E+ + S+ GQ C A + P S++ + ++L E
Sbjct: 320 FHFVHRS---ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKG---RLLEEHS 373
Query: 296 ------PSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVA----QHSDNLPPLCIPPTI 345
P+ T ++ +I +++ RI+ +E + ++ D+ + P I
Sbjct: 374 RIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCI 433
Query: 346 ISDVSWDDPSMTGENFGPILPIMRYTD--LDETIDTLIKRFDTPLVQYIFTNSKDEIDHI 403
+ +P M E FGP+L + Y D ET+ + L +F+ KD +
Sbjct: 434 VESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEA 493
Query: 404 LTRIR--SGACVVNDTLLHVGIEEAPFGGIGTSGYGNY-HGPYTFKTFTHERTI 454
+R +G +ND + + PFGG SG + GP+ +T + I
Sbjct: 494 TKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVI 547
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 61.2 bits (147), Expect = 4e-09
Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 25/350 (7%)
Query: 125 GTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPSELTPACAEVMEEICNEA-FEKGQVE 183
G + +SPFNF + A+ G N V++KPS+ ++ +I EA G V
Sbjct: 213 GFIAAVSPFNFTAIGGNLSYTPALMG-NGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVN 271
Query: 184 TVQG-GAEETSALVESGKFDKIFYTGSTTVGTIIAEKAAKSLTPCVL------ELGGKSP 236
V G + S I +TGS + ++ ++ V E GGK+
Sbjct: 272 FVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNF 331
Query: 237 VFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIYDEFVDS--CKKVLNEF 294
FI + + E+ + S+ GQ C A + P+S++ + + C+ +
Sbjct: 332 HFIHAS---ADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKI 388
Query: 295 YPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTV-----AQHSDNLPPLCIPPTIISDV 349
+ + +I ++A+ RI IE K + +SD+ + PTI+
Sbjct: 389 GDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDS-KGYFVNPTIVLSK 447
Query: 350 SWDDPSMTGENFGPILPIMRY--TDLDETIDTLIKRFDTPLVQYIFTNSKDEIDHILT-- 405
D MT E FGP+L I Y +DL ET+ + L +F +D + L
Sbjct: 448 DPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEF 507
Query: 406 RIRSGACVVNDTLLHVGIEEAPFGGIGTSGYGN-YHGPYTFKTFTHERTI 454
++ +G +ND + + PFGG SG + GP+ +T ++I
Sbjct: 508 KMAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSI 557
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 55.8 bits (133), Expect = 2e-07
Identities = 74/342 (21%), Positives = 138/342 (39%), Gaps = 31/342 (9%)
Query: 125 GTVLVISPFNFPILLALDPLAGAIAGGNSVVFKPS-ELTPACAEVMEEICNEAFEKGQVE 183
G V ++PF L + L A+ G N+V++ PS E+ P + G +
Sbjct: 202 GFVAALAPFESVALSSSLALCPALMG-NTVLWNPSLEVAPVSYLIFRAFQEAGLPSGVIN 260
Query: 184 TVQGGAEETSALVESGKFDKIFYTGSTT---------VGTIIAEKAAKSLT--PCVLELG 232
V L D + + G T V +++++ + + V E
Sbjct: 261 FVPANER----LFLDTITDAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECP 316
Query: 233 GKSPVFISPNLPKSQWETAIRRIYYSSMGNAGQICVAADYVLCPDSIY----DEFVDSCK 288
G++ F+ + ++ E+ + ++ G AGQ + + P S++ +E V++ +
Sbjct: 317 GQNFHFVHAS---AKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATE 373
Query: 289 KVLNEFYPSVTSDTEYTHMIHERAYNRIQTVIETTKGQKTVAQHS-DNLPPLCIPPTIIS 347
++ + S+T+ M+H + R+Q +++ TK + + S D+ + PTI+
Sbjct: 374 QLT--IGDPIESETDIGAMVHINDFRRMQKLLQRTKNMEQLCGGSCDDSTGRFVDPTIVR 431
Query: 348 DVSWDDPSMTGENFGPILPIMRYTD--LDETIDTLIKRFDTPLVQYIFTNSKDEIDHILT 405
DP + GP LP+ Y+D E + + L IF + + I H L
Sbjct: 432 VSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLN 491
Query: 406 RIRSGA--CVVNDTLLHVGIEEAPFGGIGTSGYGNYHGPYTF 445
++R A VN+ PFGG SG + G F
Sbjct: 492 QLRMSASNLYVNERCTGSTYGLTPFGGNRLSGTNDKSGSAYF 533
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,775,895
Number of Sequences: 60738
Number of extensions: 1398161
Number of successful extensions: 3833
Number of sequences better than 1.0e-05: 73
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 3536
Number of HSP's gapped (non-prelim): 81
length of query: 521
length of database: 30,389,216
effective HSP length: 111
effective length of query: 410
effective length of database: 23,647,298
effective search space: 9695392180
effective search space used: 9695392180
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)