ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3231 check: MH RT KOG0598 General function prediction only Ribosomal protein S6 kinase and related proteins
r_klactII3231 check: MH RT KOG0598 Signal transduction mechanisms Ribosomal protein S6 kinase and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3231 1109939 1112086 716
(716 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 869 0.0
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 832 0.0
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 516 e-146
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 345 2e-94
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 335 1e-91
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 332 1e-90
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 327 3e-89
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 323 4e-88
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 323 6e-88
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 311 2e-84
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 311 2e-84
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 309 1e-83
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 306 5e-83
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 304 4e-82
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 303 6e-82
7300106 [T] KOG0690 Serine/threonine protein kinase 303 6e-82
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 303 8e-82
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 300 5e-81
CE15612 [T] KOG0690 Serine/threonine protein kinase 298 2e-80
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 297 4e-80
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 297 4e-80
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 296 1e-79
7301734 [T] KOG0694 Serine/threonine protein kinase 295 2e-79
CE29092 [T] KOG0694 Serine/threonine protein kinase 293 5e-79
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 292 1e-78
CE05274 [T] KOG0690 Serine/threonine protein kinase 292 1e-78
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 290 5e-78
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 285 2e-76
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 283 8e-76
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 281 2e-75
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 281 2e-75
CE18646 [T] KOG0690 Serine/threonine protein kinase 281 3e-75
7302860 [T] KOG0696 Serine/threonine protein kinase 278 2e-74
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 276 6e-74
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 276 6e-74
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 276 8e-74
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 275 2e-73
CE29298 [T] KOG0690 Serine/threonine protein kinase 275 2e-73
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 274 3e-73
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 274 4e-73
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 272 1e-72
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 271 3e-72
7294770 [T] KOG0603 Ribosomal protein S6 kinase 271 3e-72
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 270 7e-72
7303111 [T] KOG0695 Serine/threonine protein kinase 270 7e-72
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 269 1e-71
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 269 1e-71
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 269 1e-71
CE02586 [T] KOG0696 Serine/threonine protein kinase 266 8e-71
YBL105c [T] KOG0694 Serine/threonine protein kinase 264 4e-70
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 264 4e-70
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 263 5e-70
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 263 7e-70
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 263 9e-70
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 263 9e-70
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 262 1e-69
7302861 [T] KOG0696 Serine/threonine protein kinase 262 2e-69
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 261 2e-69
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 261 2e-69
CE17354 [T] KOG0694 Serine/threonine protein kinase 261 2e-69
CE17353 [T] KOG0694 Serine/threonine protein kinase 261 2e-69
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 261 3e-69
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 260 4e-69
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 259 1e-68
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 256 8e-68
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 256 1e-67
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 256 1e-67
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 255 1e-67
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 254 3e-67
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 253 7e-67
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 253 7e-67
CE02604 [T] KOG0695 Serine/threonine protein kinase 253 7e-67
7295638 [T] KOG0603 Ribosomal protein S6 kinase 252 2e-66
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 244 4e-64
CE18699 [T] KOG0694 Serine/threonine protein kinase 241 4e-63
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 238 2e-62
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 238 2e-62
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 236 7e-62
7303915 [T] KOG0694 Serine/threonine protein kinase 236 9e-62
7303914 [T] KOG0694 Serine/threonine protein kinase 236 9e-62
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 235 2e-61
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 235 2e-61
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 234 3e-61
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 234 4e-61
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 232 1e-60
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 231 2e-60
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 231 2e-60
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 230 6e-60
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 230 6e-60
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 229 8e-60
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 228 3e-59
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 227 4e-59
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 227 5e-59
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 225 2e-58
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 223 1e-57
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 222 2e-57
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 221 2e-57
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 221 2e-57
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 220 5e-57
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 220 7e-57
7293735 [R] KOG0605 NDR and related serine/threonine kinases 220 7e-57
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 219 9e-57
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 219 1e-56
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 218 2e-56
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 218 2e-56
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 218 3e-56
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 216 7e-56
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 216 1e-55
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 216 1e-55
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 216 1e-55
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 215 2e-55
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 215 2e-55
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 215 2e-55
CE03979 [T] KOG0614 cGMP-dependent protein kinase 214 4e-55
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 214 5e-55
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 212 1e-54
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 211 2e-54
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 211 2e-54
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 211 3e-54
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 211 3e-54
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 210 5e-54
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 209 9e-54
CE02074 [T] KOG0986 G protein-coupled receptor kinase 209 1e-53
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 209 2e-53
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 209 2e-53
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 208 3e-53
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 208 3e-53
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 207 3e-53
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 207 3e-53
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 206 8e-53
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 206 8e-53
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 204 4e-52
7296166 [T] KOG0614 cGMP-dependent protein kinase 204 5e-52
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 203 7e-52
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 202 1e-51
CE01554 [T] KOG0986 G protein-coupled receptor kinase 201 4e-51
7302050 [T] KOG0986 G protein-coupled receptor kinase 197 6e-50
CE19898 [T] KOG0614 cGMP-dependent protein kinase 196 1e-49
CE19897 [T] KOG0614 cGMP-dependent protein kinase 196 1e-49
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 196 1e-49
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 195 2e-49
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 194 5e-49
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 193 9e-49
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 192 1e-48
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 192 1e-48
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 192 1e-48
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 190 6e-48
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 186 8e-47
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 185 2e-46
7297611 [T] KOG0614 cGMP-dependent protein kinase 185 2e-46
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 184 4e-46
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 183 7e-46
At1g16440 [R] KOG0610 Putative serine/threonine protein kinase 174 4e-43
YPL209c [D] KOG0580 Serine/threonine protein kinase 172 1e-42
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 172 2e-42
At5g35410 [T] KOG0583 Serine/threonine protein kinase 171 3e-42
At2g45490 [D] KOG0580 Serine/threonine protein kinase 168 2e-41
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 166 9e-41
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 165 2e-40
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 164 6e-40
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 164 6e-40
At3g14370 [R] KOG0610 Putative serine/threonine protein kinase 164 6e-40
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 163 7e-40
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 163 7e-40
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 162 2e-39
At2g25090 [T] KOG0583 Serine/threonine protein kinase 162 2e-39
At5g45810 [T] KOG0583 Serine/threonine protein kinase 161 3e-39
7299536 [D] KOG0580 Serine/threonine protein kinase 161 4e-39
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 160 5e-39
At4g24400 [T] KOG0583 Serine/threonine protein kinase 160 5e-39
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 160 8e-39
At4g18700 [T] KOG0583 Serine/threonine protein kinase 159 1e-38
At2g30360 [T] KOG0583 Serine/threonine protein kinase 159 1e-38
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 158 2e-38
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 158 3e-38
At1g51170 [R] KOG0610 Putative serine/threonine protein kinase 157 4e-38
At1g29230 [T] KOG0583 Serine/threonine protein kinase 157 4e-38
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 157 7e-38
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 157 7e-38
CE24761 [D] KOG0580 Serine/threonine protein kinase 157 7e-38
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 156 9e-38
At3g20830 [R] KOG0610 Putative serine/threonine protein kinase 156 1e-37
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 155 2e-37
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 155 2e-37
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 155 3e-37
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 155 3e-37
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 155 3e-37
CE00847 [T] KOG0583 Serine/threonine protein kinase 154 3e-37
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 154 5e-37
At5g39440 [T] KOG0583 Serine/threonine protein kinase 153 8e-37
At4g32830 [D] KOG0580 Serine/threonine protein kinase 153 8e-37
At4g30960 [T] KOG0583 Serine/threonine protein kinase 153 1e-36
At2g25880 [D] KOG0580 Serine/threonine protein kinase 152 1e-36
At5g25110 [T] KOG0583 Serine/threonine protein kinase 152 2e-36
At2g26980 [T] KOG0583 Serine/threonine protein kinase 152 2e-36
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 151 3e-36
At3g01090 [T] KOG0583 Serine/threonine protein kinase 151 3e-36
At5g10930 [T] KOG0583 Serine/threonine protein kinase 151 4e-36
At2g34180 [T] KOG0583 Serine/threonine protein kinase 150 5e-36
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 150 7e-36
7297776 [D] KOG0580 Serine/threonine protein kinase 149 1e-35
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 149 2e-35
At1g30270 [T] KOG0583 Serine/threonine protein kinase 149 2e-35
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 148 2e-35
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 147 4e-35
CE27768 [R] KOG0586 Serine/threonine protein kinase 147 4e-35
CE23838 [R] KOG0586 Serine/threonine protein kinase 147 4e-35
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 147 6e-35
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 147 6e-35
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 147 6e-35
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 147 6e-35
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 146 9e-35
CE28643 [T] KOG0583 Serine/threonine protein kinase 146 9e-35
CE07458 [T] KOG0583 Serine/threonine protein kinase 146 9e-35
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 146 9e-35
At5g45820 [T] KOG0583 Serine/threonine protein kinase 145 2e-34
At4g14580 [T] KOG0583 Serine/threonine protein kinase 145 2e-34
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 145 3e-34
7290150 [T] KOG0583 Serine/threonine protein kinase 145 3e-34
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 144 4e-34
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 144 4e-34
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 144 4e-34
At5g57630 [T] KOG0583 Serine/threonine protein kinase 144 4e-34
At3g29160 [T] KOG0583 Serine/threonine protein kinase 144 4e-34
At3g23000 [T] KOG0583 Serine/threonine protein kinase 144 5e-34
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 143 1e-33
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 143 1e-33
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 143 1e-33
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 142 1e-33
CE29300 [T] KOG0694 Serine/threonine protein kinase 142 2e-33
CE29299 [T] KOG0694 Serine/threonine protein kinase 142 2e-33
At5g01820 [T] KOG0583 Serine/threonine protein kinase 142 2e-33
7302464 [R] KOG0586 Serine/threonine protein kinase 142 2e-33
7294217 [D] KOG0588 Serine/threonine protein kinase 141 4e-33
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 140 5e-33
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 140 5e-33
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 7e-33
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 140 9e-33
CE21025 [D] KOG0580 Serine/threonine protein kinase 140 9e-33
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 139 1e-32
At2g38490 [T] KOG0583 Serine/threonine protein kinase 139 1e-32
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 139 2e-32
CE17284 [T] KOG0583 Serine/threonine protein kinase 139 2e-32
CE28218 [D] KOG0588 Serine/threonine protein kinase 139 2e-32
7290249 [R] KOG0586 Serine/threonine protein kinase 139 2e-32
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 138 3e-32
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 138 3e-32
Hs22053778_2 [T] KOG0986 G protein-coupled receptor kinase 138 3e-32
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 137 4e-32
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 137 4e-32
At1g01140 [T] KOG0583 Serine/threonine protein kinase 137 4e-32
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 137 4e-32
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 137 6e-32
YDR477w [T] KOG0583 Serine/threonine protein kinase 137 7e-32
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 137 7e-32
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 136 1e-31
YOR233w [T] KOG0583 Serine/threonine protein kinase 136 1e-31
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 135 2e-31
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 135 2e-31
YKL101w [D] KOG0588 Serine/threonine protein kinase 135 3e-31
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 135 3e-31
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 135 3e-31
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 134 4e-31
At4g40010 [T] KOG0583 Serine/threonine protein kinase 134 4e-31
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 134 5e-31
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 134 5e-31
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 134 5e-31
At5g01810 [T] KOG0583 Serine/threonine protein kinase 134 5e-31
At3g17510 [T] KOG0583 Serine/threonine protein kinase 134 5e-31
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 134 6e-31
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 134 6e-31
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 134 6e-31
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 134 6e-31
7299437 [R] KOG0586 Serine/threonine protein kinase 134 6e-31
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 134 6e-31
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 133 1e-30
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 133 1e-30
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 133 1e-30
At5g08590 [T] KOG0583 Serine/threonine protein kinase 132 1e-30
At1g48260 [T] KOG0583 Serine/threonine protein kinase 132 1e-30
At5g66880 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 132 2e-30
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 2e-30
At5g58380 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
At4g33950 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 131 4e-30
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 131 4e-30
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 131 4e-30
7299438 [R] KOG0586 Serine/threonine protein kinase 130 5e-30
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 130 7e-30
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 130 7e-30
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 7e-30
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 7e-30
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 130 9e-30
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 129 1e-29
At1g78290 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 129 2e-29
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 129 2e-29
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 129 2e-29
At2g23030 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 129 2e-29
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 128 3e-29
At5g63650 [T] KOG0583 Serine/threonine protein kinase 128 3e-29
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 127 5e-29
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 127 8e-29
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 8e-29
YLR096w [T] KOG0583 Serine/threonine protein kinase 126 1e-28
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 126 1e-28
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 126 1e-28
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 126 1e-28
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 126 1e-28
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 1e-28
7303211 [T] KOG4717 Serine/threonine protein kinase 126 1e-28
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
ECU10g0570 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 125 2e-28
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 2e-28
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 125 3e-28
Hs22065405 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 125 3e-28
At5g07070 [T] KOG0583 Serine/threonine protein kinase 125 3e-28
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 3e-28
At3g50500 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
At2g20040 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 124 5e-28
At1g60940 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 124 5e-28
7302570 [R] KOG0586 Serine/threonine protein kinase 123 9e-28
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 123 1e-27
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 123 1e-27
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 1e-27
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 122 1e-27
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 122 1e-27
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 1e-27
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 1e-27
At1g10940 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 122 2e-27
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 2e-27
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 122 2e-27
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 122 2e-27
YPL150w [T] KOG0583 Serine/threonine protein kinase 121 3e-27
YPL141c [T] KOG0583 Serine/threonine protein kinase 121 3e-27
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 121 3e-27
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 3e-27
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 121 4e-27
YDR507c [D] KOG0588 Serine/threonine protein kinase 121 4e-27
CE28479 [T] KOG0583 Serine/threonine protein kinase 121 4e-27
Hs21450709 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 120 6e-27
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 120 6e-27
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 120 6e-27
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 6e-27
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 120 7e-27
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 120 7e-27
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 7e-27
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 7e-27
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 120 9e-27
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 120 9e-27
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 120 9e-27
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 120 9e-27
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 119 1e-26
YDR122w [T] KOG0583 Serine/threonine protein kinase 119 2e-26
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 119 2e-26
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 119 2e-26
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 118 3e-26
Hs22043324 [T] KOG0603 Ribosomal protein S6 kinase 118 3e-26
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 118 3e-26
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 118 3e-26
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 3e-26
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 118 3e-26
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 118 4e-26
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 4e-26
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 4e-26
YCL024w [T] KOG0583 Serine/threonine protein kinase 117 5e-26
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 117 5e-26
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 117 5e-26
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 5e-26
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 117 6e-26
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 117 6e-26
CE16081 [T] KOG0583 Serine/threonine protein kinase 117 6e-26
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 6e-26
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 117 6e-26
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 117 8e-26
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 117 8e-26
YHR102w [T] KOG0201 Serine/threonine protein kinase 116 1e-25
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 116 1e-25
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 116 1e-25
At3g15220 [T] KOG0201 Serine/threonine protein kinase 116 1e-25
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 116 1e-25
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 116 1e-25
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 116 1e-25
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 116 1e-25
7300224 [T] KOG0201 Serine/threonine protein kinase 116 1e-25
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 115 2e-25
At5g40030 [R] KOG0610 Putative serine/threonine protein kinase 115 2e-25
At3g20860 [R] KOG0589 Serine/threonine protein kinase 115 2e-25
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 115 2e-25
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 2e-25
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 115 3e-25
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 115 3e-25
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 115 3e-25
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 3e-25
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 3e-25
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 115 3e-25
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 114 4e-25
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 114 5e-25
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 5e-25
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 5e-25
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 114 7e-25
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 114 7e-25
At5g28290 [R] KOG0589 Serine/threonine protein kinase 114 7e-25
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 114 7e-25
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 113 9e-25
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 113 9e-25
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 113 9e-25
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 113 9e-25
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 113 9e-25
YJL128c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 113 1e-24
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 113 1e-24
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 113 1e-24
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 113 1e-24
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 1e-24
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 112 2e-24
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 112 2e-24
Hs14759411 [TR] KOG0606 Microtubule-associated serine/threonine ... 112 2e-24
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 112 2e-24
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 112 2e-24
At1g54510 [R] KOG0589 Serine/threonine protein kinase 112 2e-24
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 112 3e-24
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 111 3e-24
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 111 3e-24
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 111 3e-24
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 111 4e-24
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 4e-24
CE21239 [T] KOG0583 Serine/threonine protein kinase 111 4e-24
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 111 4e-24
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 110 6e-24
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 110 6e-24
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 110 6e-24
At3g04810 [R] KOG0589 Serine/threonine protein kinase 110 6e-24
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 110 6e-24
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 110 7e-24
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 110 1e-23
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 110 1e-23
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 110 1e-23
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 110 1e-23
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 110 1e-23
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 110 1e-23
CE28674 [T] KOG0201 Serine/threonine protein kinase 110 1e-23
CE07510 [T] KOG0201 Serine/threonine protein kinase 110 1e-23
At3g52890 [R] KOG0610 Putative serine/threonine protein kinase 110 1e-23
At1g79250 [R] KOG0610 Putative serine/threonine protein kinase 110 1e-23
At1g53165 [T] KOG0201 Serine/threonine protein kinase 110 1e-23
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 109 1e-23
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 109 1e-23
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 109 1e-23
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 109 1e-23
CE18454 [T] KOG4717 Serine/threonine protein kinase 109 1e-23
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 109 1e-23
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 109 1e-23
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 1e-23
At2g36350 [R] KOG0610 Putative serine/threonine protein kinase 109 1e-23
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 109 2e-23
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 109 2e-23
CE18366 [T] KOG0583 Serine/threonine protein kinase 108 2e-23
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
7300413 [T] KOG0583 Serine/threonine protein kinase 108 2e-23
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 108 2e-23
YDR523c [T] KOG0201 Serine/threonine protein kinase 108 3e-23
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 108 3e-23
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 108 3e-23
CE17343 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 108 4e-23
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 108 4e-23
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 108 4e-23
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 108 4e-23
At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase 108 4e-23
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 108 4e-23
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 107 5e-23
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 107 5e-23
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 107 5e-23
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 107 5e-23
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 107 6e-23
CE23001 [R] KOG0589 Serine/threonine protein kinase 107 6e-23
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 107 6e-23
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 107 6e-23
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 107 8e-23
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 106 1e-22
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 105 2e-22
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 105 2e-22
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 105 2e-22
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 105 2e-22
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 105 3e-22
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 869 bits (2246), Expect = 0.0
Identities = 451/732 (61%), Positives = 532/732 (72%), Gaps = 69/732 (9%)
Query: 1 MYSWKLSSKFRFGRSXXXXXXXXXX--------------XXXXXIDGNDNRSSVDRKATI 46
MYSWK SKF+FG+S D + RSS+DRK TI
Sbjct: 1 MYSWK--SKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHDASITRSSLDRKGTI 58
Query: 47 VPGSATVVQXXXXXXXXXXXXXXGHSVHSSGFKGTITEGSMSTDISGEDISMTNGRDRDS 106
P +++VV S +G T S + D + +I T G D+
Sbjct: 59 NPSNSSVVPVRVSYDASSSTSTVRDS---NGGNSENTNSSQNLDETA-NIGST-GTPNDA 113
Query: 107 TEVQXXXXXXXXXFKXXXXXXXXXXXXXXXXXXXXXXXPVENENTHSSNGILTVKVYSGD 166
T SS+G++T+KVY+GD
Sbjct: 114 T---------------------------------------------SSSGMMTIKVYNGD 128
Query: 167 SFKLPLPITYNEQVLSKLLSSGVDVTSTTQQDSLEELIQSMHGLSLLRE---EDKLLSGE 223
F LP PIT +EQ+L+KLL+SGV ++ LI + + + + ++ L+S E
Sbjct: 129 DFILPFPITSSEQILNKLLASGVPPPHKEISKEVDALIAQLSRVQIKNQGPADEDLISSE 188
Query: 224 DASHFIPASVILPGSKNLNSLLYFTIEFDNTIATIEPESGTLNRPIFNKISTFDVTRRLP 283
A+ FIP++++LPGS LN LLYFTIEFDNT+ATIE E GT+ +P FNKISTFDVTR+LP
Sbjct: 189 SAAKFIPSTIMLPGSSTLNPLLYFTIEFDNTVATIEAEYGTIAKPGFNKISTFDVTRKLP 248
Query: 284 FLKIDVFARIPSILLPSQNWQETQISNNDILGDYVKKIRNNSDIHLDSFHLPLNLKIDSA 343
+LKIDVFARIPSILLPS+ WQ+ ++ L KI +N DIHLDSFHLP+NL DSA
Sbjct: 249 YLKIDVFARIPSILLPSKTWQQEMGLQDEKLQTIFDKINSNQDIHLDSFHLPINLSFDSA 308
Query: 344 SNIRLYNHHWIELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRD 403
++IRLYNHHWI L++ +GK+N+S+DYKPS +K LSIDDFDLLKVIGKGSFGKVMQVRK+D
Sbjct: 309 ASIRLYNHHWITLDNGLGKINISIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKD 368
Query: 404 TNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFIN 463
T K+YALKAIRKSYIVSKSEVTHTLAERTVLARVD PFIVPLKFSFQS EKLY VLAFIN
Sbjct: 369 TQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFIN 428
Query: 464 GGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCD 523
GGELFYHLQ+EGRFDLSR+RFYTAELLCAL+ LH D++YRDLKPENILLDYQGHIALCD
Sbjct: 429 GGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCD 488
Query: 524 FGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDE 583
FGLCKLNMKD +KT TFCGTPEYLAPELLLG GYTK VDWWTLGVLLYEMLTGLPPYYDE
Sbjct: 489 FGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDE 548
Query: 584 DVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWK 643
DVPKMYKKILQ+PL FPD FD+DAKDLLIGLL RDP RRLGY+G+DEI++HPFF+QLSWK
Sbjct: 549 DVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWK 608
Query: 644 RLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYVGSEQ 703
RL MKGYIPPYKP V +MDTSNFD+EFTRE+P+DSVV+++LSESVQ+QFGGWTYVG+EQ
Sbjct: 609 RLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGGWTYVGNEQ 668
Query: 704 LGQSMLPDRSFQ 715
LG SM+ RS +
Sbjct: 669 LGSSMVQGRSIR 680
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 832 bits (2149), Expect = 0.0
Identities = 406/573 (70%), Positives = 471/573 (81%), Gaps = 9/573 (1%)
Query: 147 ENENTHSSNGILTVKVYSGDSFKLPLPITYNEQVLSKLLSSGVDVTSTTQQDSLEELIQS 206
E + S +G++TVKVYSG F LP PIT N +L KLLSSG+ T+ + E+
Sbjct: 106 ETQGPSSESGLMTVKVYSGKDFTLPFPITSNSTILQKLLSSGI---LTSSSNDASEVAAI 162
Query: 207 MHGLSLLREEDKLLSGED------ASHFIPASVILPGSKNLNSLLYFTIEFDNTIATIEP 260
M L + D+ +GE A+ FIP+S++LPGS N + LLYFTIEFDN+I TI P
Sbjct: 163 MRQLPRYKRVDQDSAGEGLIDRAFATKFIPSSILLPGSTNSSPLLYFTIEFDNSITTISP 222
Query: 261 ESGTLNRPIFNKISTFDVTRRLPFLKIDVFARIPSILLPSQNWQETQISNNDILGDYVKK 320
+ GT+ +P+FNKISTFDVTR+L FLKIDVFARIPS+LLPS+NWQ+ +++L + +KK
Sbjct: 223 DMGTMEQPVFNKISTFDVTRKLRFLKIDVFARIPSLLLPSKNWQQEIGEQDEVLKEILKK 282
Query: 321 IRNNSDIHLDSFHLPLNLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPSTHKHLSID 380
I N DIHLDSFHLPLNLKIDSA+ IRLYNHHWI LE GKLN++VDYKPS +K LSID
Sbjct: 283 INTNQDIHLDSFHLPLNLKIDSAAQIRLYNHHWISLERGYGKLNITVDYKPSKNKPLSID 342
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DFDLLKVIGKGSFGKVMQVRK+DT KIYALKA+RK+YIVSK EVTHTLAERTVLARVD P
Sbjct: 343 DFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCP 402
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
FIVPLKFSFQS EKLYLVLAFINGGELFYHLQ EGRF L+RSRFY AELLCAL++LH D
Sbjct: 403 FIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLD 462
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKV 560
+IYRDLKPENILLDYQGHIALCDFGLCKLNMKD +KT TFCGTPEYLAPE+LLGQGYTK
Sbjct: 463 VIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKT 522
Query: 561 VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPK 620
VDWWTLG+LLYEM+TGLPPYYDE+VP MYKKILQ PL FPD FD AKDLLIGLL RDP
Sbjct: 523 VDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPS 582
Query: 621 RRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDSV 680
RRLG +G+DEI++HPFF +SWK+L +KGYIPPYKP V +DT+NFDQEFT+E+P+DSV
Sbjct: 583 RRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSV 642
Query: 681 VNDFLSESVQQQFGGWTYVGSEQLGQSMLPDRS 713
V+++LS S+Q+QFGGWTY+G EQLG S RS
Sbjct: 643 VDEYLSASIQKQFGGWTYIGDEQLGDSPSQGRS 675
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 516 bits (1329), Expect = e-146
Identities = 265/457 (57%), Positives = 330/457 (71%), Gaps = 30/457 (6%)
Query: 244 LLYFTIEFD-NTIATIEPESGTLNRPIFNKISTFDVTRRLPFLKIDVFARIPSILLPSQN 302
L Y +EFD N I + +L P ++ +TFDV+R L ++++ R S +
Sbjct: 119 LPYIVVEFDKNEILVDALNTASLENPCWDYQATFDVSRYSK-LSLNIYLR------SSSS 171
Query: 303 WQETQISNNDILGDYVKKIRNNSDIHLDSFHLPLNLKIDSASNIRLYNHHWIELESKMGK 362
+ N+ LG +K+ + + W+ L G+
Sbjct: 172 RSRNGMGNDAFLG---------------------GIKLSPSFIVNKLTDEWVPLHGGSGE 210
Query: 363 LNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKS 422
L + + YKP+ L+ID F+LLKV+GKGSFGKVMQVRKRDT++IYALK ++K++IVS+S
Sbjct: 211 LRVQMLYKPNQSTPLTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRS 270
Query: 423 EVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRS 482
EV HTLAERTVLA+V+NPFIVPLKFSFQS KLYLVLAF+NGGELF+HLQREG FD R+
Sbjct: 271 EVDHTLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRA 330
Query: 483 RFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCG 542
+FY AELL ALE LH+F++IYRDLKPENILLDY GHIALCDFGLCKLNM ++T TFCG
Sbjct: 331 KFYIAELLVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCG 390
Query: 543 TPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD 602
TPEYLAPELLLG GYTKVVDWWTLGVLLYEM+TGLPP+YDE++ +MY+KILQDPLRFPD+
Sbjct: 391 TPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDN 450
Query: 603 FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
D+ AKDLL GLL R P++RLG G+ EIK+HPFF+ + WK+L K PP+KP V A+
Sbjct: 451 IDEKAKDLLSGLLTRAPEKRLGSGGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAI 510
Query: 663 DTSNFDQEFTREQPVDSVVND-FLSESVQQQFGGWTY 698
DTSNFD EFT E P+DSVV D LSE+VQQ+F W+Y
Sbjct: 511 DTSNFDSEFTSEIPMDSVVADSHLSETVQQRFANWSY 547
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 345 bits (884), Expect = 2e-94
Identities = 181/384 (47%), Positives = 256/384 (66%), Gaps = 24/384 (6%)
Query: 351 HHWIELESKM------GKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDT 404
H W L+ ++ G + + YK + +H DF++L+++GKG+FG+V QV+K+DT
Sbjct: 375 HQWHSLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDT 434
Query: 405 NKIYALKAIRKSYIVSKSEVTHTLAERTVL---ARVDNPFIVPLKFSFQSSEKLYLVLAF 461
+IYA+K + K IV K+E+ HT+ ER +L A +PFIV LKFSFQ+ LYLV +
Sbjct: 435 QRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDY 494
Query: 462 INGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIAL 521
++GGELF+HLQ+EGRF R++FY AEL+ ALE LHD DI+YRDLKPENILLD G+IAL
Sbjct: 495 MSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIAL 554
Query: 522 CDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ-GYTKVVDWWTLGVLLYEMLTGLPPY 580
CDFGL K ++KD +T TFCGT EYLAPELLL + GYTK+VD+W+LGVL++EM G P+
Sbjct: 555 CDFGLSKADLKD--RTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPF 612
Query: 581 YDEDVPKMYKKILQDPLRFPDD-FDKDAKDLLIGLLCRDPKRRLG-YHGSDEIKSHPFFN 638
+ E+ KMY+KI ++FP D ++ + + GLL R+PK RLG E+++HPFF
Sbjct: 613 FAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFA 672
Query: 639 QLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFT--------REQPVDSVVNDFLSESVQ 690
+ W+ LK K PP+KP ++ DTSNFD EFT + QP+ + LS ++Q
Sbjct: 673 DIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATP--LSPAMQ 730
Query: 691 QQFGGWTYVGSEQLGQSMLPDRSF 714
+F G+T+V + + + +R F
Sbjct: 731 AKFAGFTFVDESAIDEHVNNNRKF 754
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 335 bits (860), Expect = 1e-91
Identities = 181/368 (49%), Positives = 238/368 (64%), Gaps = 21/368 (5%)
Query: 353 WIELE------SKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNK 406
W +LE S G++ + Y+ H +DF L++IGKG+FG+V VRK DTN+
Sbjct: 267 WYKLEPLDLTKSLEGEIKVETIYEHIEHVRYGPEDFTALRLIGKGTFGQVYLVRKNDTNR 326
Query: 407 IYALKAIRKSYIVSKSEVTHTLAERTVLARV---DNPFIVPLKFSFQSSEKLYLVLAFIN 463
IYA+K I K IV K EVTHTL ER +L R ++PFIV LKFSFQ++ LYL+ +++
Sbjct: 327 IYAMKKISKKLIVRKKEVTHTLGERNILVRTSLDESPFIVGLKFSFQTASDLYLITDYMS 386
Query: 464 GGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCD 523
GGELF+HLQ EGRF R++FY AEL+ ALE LH DIIYRDLKPENILLD GHIALCD
Sbjct: 387 GGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCD 446
Query: 524 FGLCKLNMKDQEKTTTFCGTPEYLAPELLL-GQGYTKVVDWWTLGVLLYEMLTGLPPYYD 582
FGL K N+ T TFCGT EYLAPE+LL +GYTK VD+W+LGVL++EM G P+Y
Sbjct: 447 FGLSKANLSANATTNTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYA 506
Query: 583 EDVPKMYKKILQDPLRFPDD-FDKDAKDLLIGLLCRDPKRRLG-YHGSDEIKSHPFFNQL 640
DV +MY+ I +RFP + + + GLL R+P RLG + E+K HPFF +
Sbjct: 507 PDVQQMYRNIAFGKVRFPKGVLSSEGRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADI 566
Query: 641 SWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVD-SVVNDF--------LSESVQQ 691
+W L K PP+KP V +D SNFD+EFT + ++V++ LS ++Q
Sbjct: 567 NWDLLSKKKVQPPFKPNVQNDLDVSNFDKEFTNTNVKNINIVSNVDPANASTPLSNTIQD 626
Query: 692 QFGGWTYV 699
+F G+T+V
Sbjct: 627 RFRGFTFV 634
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 332 bits (851), Expect = 1e-90
Identities = 175/363 (48%), Positives = 241/363 (66%), Gaps = 21/363 (5%)
Query: 362 KLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSK 421
+L+L+ ++P + DDF LK+IGKG+FG+V VRK+DT ++YA+K + K IV +
Sbjct: 246 RLSLNTVFQPLSQHSYGPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRR 305
Query: 422 SEVTHTLAERTVLARV---DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFD 478
EV HT+ ER +L + D+PFIV L+FSFQ+ + LYLV ++ GGELF+HLQ+ RF
Sbjct: 306 KEVAHTVGERDILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFP 365
Query: 479 LSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTT 538
R++FY AELL AL+ALH I+YRDLKPENILLD QGHIALCDFGL K N+ T
Sbjct: 366 EERAKFYIAELLLALQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTR 425
Query: 539 TFCGTPEYLAPELLLGQ-GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPL 597
TFCGT +YLAPE++L + GY +VD+W+LGVLLYEM G P+Y ++ ++YK I+ +
Sbjct: 426 TFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKV 485
Query: 598 RFPDD-FDKDAKDLLIGLLCRDPKRRLGYHGS-DEIKSHPFFNQLSWKRLKMKGYIPPYK 655
RFP +A+DL+ LL R+PK RLG HG +E+ HPFF+ + WK+L K PP+K
Sbjct: 486 RFPRGLLSVEARDLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDWKKLAAKEISPPFK 545
Query: 656 PPVMGAMDTSNFDQEFTREQPVDSVVNDF-----------LSESVQQQFGGWTYVGSEQL 704
P V G +D SNFD EFT + ++ DF LS +VQ F G+TY+ + +
Sbjct: 546 PIVEGEIDVSNFDVEFTNK----AIDRDFSSTDEMSTSAPLSSTVQNGFKGFTYIDASAM 601
Query: 705 GQS 707
++
Sbjct: 602 DEA 604
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 327 bits (839), Expect = 3e-89
Identities = 164/312 (52%), Positives = 212/312 (67%), Gaps = 2/312 (0%)
Query: 366 SVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVT 425
+VD PS K + +DFD L IGKGSFG+V QVR ++T KIYA+K + K +I K+EV
Sbjct: 78 NVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVK 137
Query: 426 HTLAERTVLAR-VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRF 484
H +AER VL +PF+V L FSFQ+ EKLY VL +NGGELF HLQRE F SRSRF
Sbjct: 138 HVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRF 197
Query: 485 YTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTP 544
Y AE+ CAL LH+ +IIYRDLKPEN+LLD +G++ L DFGLCK +M+ + T+TFCGTP
Sbjct: 198 YAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTP 257
Query: 545 EYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFD 604
EYLAPE++L + Y K VDWW LG +LYEM+ GLPP+Y +D +MY KI+ PLR +
Sbjct: 258 EYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNIS 317
Query: 605 KDAKDLLIGLLCRDPKRRLGYHGS-DEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMD 663
+L+ GLL +D +RLG+ +I+ HPFF + W +L + P+ P V AMD
Sbjct: 318 VPCSELITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMD 377
Query: 664 TSNFDQEFTREQ 675
TSN +EF Q
Sbjct: 378 TSNISKEFVEIQ 389
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 323 bits (829), Expect = 4e-88
Identities = 185/395 (46%), Positives = 239/395 (59%), Gaps = 16/395 (4%)
Query: 314 LGDYVKKIRNNSDIHLDSFHLPLNLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPST 373
L D+++KI NNS + LKI L N + S ++NL PS+
Sbjct: 35 LNDFIQKIANNS-YACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLG----PSS 89
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
+ H DF LKVIGKGSFGKV+ R + YA+K ++K I+ K E H ++ER V
Sbjct: 90 NPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNV 149
Query: 434 LAR-VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
L + V +PF+V L FSFQ+++KLY VL +INGGELFYHLQRE F R+RFY AE+ A
Sbjct: 150 LLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASA 209
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELL 552
L LH +I+YRDLKPENILLD QGHI L DFGLCK N++ T+TFCGTPEYLAPE+L
Sbjct: 210 LGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVL 269
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
Q Y + VDWW LG +LYEML GLPP+Y + +MY IL PL+ + A+ LL
Sbjct: 270 HKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLE 329
Query: 613 GLLCRDPKRRLGYHGS-DEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEF 671
GLL +D +RLG EIKSH FF+ ++W L K PP+ P V G + +FD EF
Sbjct: 330 GLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDPEF 389
Query: 672 TREQPV--------DSVVNDFLSESVQQQFGGWTY 698
T E+PV DSV+ + + F G++Y
Sbjct: 390 T-EEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSY 423
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 323 bits (828), Expect = 6e-88
Identities = 161/321 (50%), Positives = 219/321 (68%), Gaps = 2/321 (0%)
Query: 362 KLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSK 421
+ N +++ PS + + DFD LKVIGKG++GKV+ +++ YA+K ++K I+ K
Sbjct: 75 RANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKK 134
Query: 422 SEVTHTLAERTVLAR-VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLS 480
E +H +AER+VL + V +PF+V L++SFQ+ EKLY VL ++NGGELF+HLQRE RF
Sbjct: 135 KEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEP 194
Query: 481 RSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTF 540
R+RFY AE+ A+ LH +IIYRDLKPENILLD QGH+ L DFGLCK ++ ++ T+TF
Sbjct: 195 RARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTF 254
Query: 541 CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP 600
CGTPEYLAPE+L + Y + VDWW LG +LYEML GLPP+Y +DV +MY+ IL PL+ P
Sbjct: 255 CGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIP 314
Query: 601 DDFDKDAKDLLIGLLCRDPKRRLGYHGSD-EIKSHPFFNQLSWKRLKMKGYIPPYKPPVM 659
A DLL LL +D ++RLG EIK+H FF+ ++W L K PP+ P V
Sbjct: 315 GGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVT 374
Query: 660 GAMDTSNFDQEFTREQPVDSV 680
G D +FD EFT+E S+
Sbjct: 375 GPADLKHFDPEFTQEAVSKSI 395
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 311 bits (798), Expect = 2e-84
Identities = 160/318 (50%), Positives = 205/318 (64%), Gaps = 2/318 (0%)
Query: 359 KMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYI 418
K+ + +++ PS + H DFD LKVIGKGSFGKV+ +++ K+YA+K ++K +
Sbjct: 21 KLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIV 80
Query: 419 VSKSEVTHTLAERTVLAR-VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRF 477
+++ E H +AER VL + V +PF+V L +SFQ++EKLY VL F+NGGELF+HLQRE F
Sbjct: 81 LNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSF 140
Query: 478 DLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKT 537
R+RFY AE+ AL LH I+YRDLKPENIL+D GH+ L DFGLCK + + T
Sbjct: 141 PEHRARFYAAEIASALGYLHSIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTT 200
Query: 538 TTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPL 597
TTFCGTPEYLAPE++ Q Y VDWW LG +LYEML GLPP+Y DV +MY IL PL
Sbjct: 201 TTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPL 260
Query: 598 RFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSD-EIKSHPFFNQLSWKRLKMKGYIPPYKP 656
A +L LL +D + RLG EI++HPFF LSW L K PP+ P
Sbjct: 261 SLRPGVSLRAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNP 320
Query: 657 PVMGAMDTSNFDQEFTRE 674
V G D NFD FT E
Sbjct: 321 NVAGPDDIRNFDTAFTEE 338
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 311 bits (797), Expect = 2e-84
Identities = 148/310 (47%), Positives = 209/310 (66%), Gaps = 2/310 (0%)
Query: 367 VDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTH 426
+D + HK +++DFD LK++GKG+FGKV+ VR++ + K YA+K ++K I++K EV H
Sbjct: 133 MDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAH 192
Query: 427 TLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYT 486
TL E VL +PF+ LK+SFQ+ ++L V+ ++NGGELF+HL RE F R+RFY
Sbjct: 193 TLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYG 252
Query: 487 AELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEY 546
AE++ AL+ LH I+YRDLK EN++LD GHI + DFGLCK + D TFCGTPEY
Sbjct: 253 AEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEY 312
Query: 547 LAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKD 606
LAPE+L Y + VDWW LGV++YEM+ G P+Y++D K+++ IL + ++FP D
Sbjct: 313 LAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSD 372
Query: 607 AKDLLIGLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDT 664
AK LL GLL +DP +RLG D EI H FF+ ++W+ + K +PP+KP V DT
Sbjct: 373 AKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDT 432
Query: 665 SNFDQEFTRE 674
FD+EFT +
Sbjct: 433 RYFDEEFTAQ 442
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 309 bits (791), Expect = 1e-83
Identities = 161/329 (48%), Positives = 219/329 (65%), Gaps = 6/329 (1%)
Query: 382 FDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVT-HTLAERTVLARV 437
F+LL+V+GKG +GKV QVRK +T KI+A+K ++K+ IV ++ T HT AER +L V
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 438 DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
+PFIV L ++FQ+ KLYL+L +++GGELF L+REG F + FY AE+ AL LH
Sbjct: 151 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 210
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGY 557
IIYRDLKPENI+L++QGH+ L DFGLCK ++ D T TFCGT EY+APE+L+ G+
Sbjct: 211 QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGH 270
Query: 558 TKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
+ VDWW+LG L+Y+MLTG PP+ E+ K KIL+ L P ++A+DLL LL R
Sbjct: 271 NRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKR 330
Query: 618 DPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQ 675
+ RLG D E+++HPFF ++W+ L + PP+KP + D S FD +FTR+
Sbjct: 331 NAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQT 390
Query: 676 PVDSVVNDFLSESVQQQFGGWTYVGSEQL 704
PVDS + LSES Q F G+TYV L
Sbjct: 391 PVDSPDDSTLSESANQVFLGFTYVAPSVL 419
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 306 bits (785), Expect = 5e-83
Identities = 144/300 (48%), Positives = 206/300 (68%), Gaps = 2/300 (0%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
++++DFD LK++GKG+FGKV+ VR++ T + YA+K +RK I++K EV HT+ E VL
Sbjct: 147 VTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQN 206
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+PF+ LK++FQ+ ++L V+ + NGGELF+HL RE F R+RFY AE++ ALE L
Sbjct: 207 TRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYL 266
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H D++YRD+K EN++LD GHI + DFGLCK + D TFCGTPEYLAPE+L
Sbjct: 267 HSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDND 326
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
Y + VDWW LGV++YEM+ G P+Y++D ++++ IL + +RFP +AK LL GLL
Sbjct: 327 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLK 386
Query: 617 RDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
+DPK+RLG SD E+ H FF ++W+ + K +PP+KP V +DT FD EFT +
Sbjct: 387 KDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQ 446
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 304 bits (778), Expect = 4e-82
Identities = 147/325 (45%), Positives = 223/325 (68%), Gaps = 4/325 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ IDDF+++KV+GKG+FGKV QVRK++T++IYA+K +RK +I+ K+ + AER +L +
Sbjct: 129 VGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTK 188
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+D+PFIV LK+SFQ+ +LYLVL FINGG LF+ L +G F +R YTAE++ A+ L
Sbjct: 189 IDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHL 248
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H+ I++RDLKPENIL+D GH+ L DFGL K ++ ++ + CGT EY+APE++ G+G
Sbjct: 249 HEKGIMHRDLKPENILMDTDGHVMLTDFGLAK-EFEENTRSNSMCGTTEYMAPEIVRGKG 307
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
+ K DWW++G+LLYEMLTG PP+ K+ +KI++D ++ P +A +L GLL
Sbjct: 308 HDKAADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHAILKGLLQ 366
Query: 617 RDPKRRL--GYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
++P+RRL G G++EIK H +F ++WK+L+ + +P +KP V G +NFD+ +T
Sbjct: 367 KEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTDM 426
Query: 675 QPVDSVVNDFLSESVQQQFGGWTYV 699
+DS + S+ F +TYV
Sbjct: 427 SVLDSPASSPSSDPKANPFTNFTYV 451
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 303 bits (776), Expect = 6e-82
Identities = 146/323 (45%), Positives = 213/323 (65%), Gaps = 3/323 (0%)
Query: 370 KPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA 429
+PS L I+DF L K++GKGSFGKV + TN+ +A+KA++K ++ +V T+
Sbjct: 368 RPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMV 427
Query: 430 ERTVLARV-DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAE 488
E+ VL+ ++PF+ + +FQ+ E L+ V+ ++NGG+L YH+Q +FDLSR+ FY AE
Sbjct: 428 EKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAE 487
Query: 489 LLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLA 548
++ L+ LH I+YRDLK +NILLD GHI + DFG+CK NM KT TFCGTP+Y+A
Sbjct: 488 IILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIA 547
Query: 549 PELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
PE+LLGQ Y VDWW+ GVLLYEML G P++ +D +++ I D +P +K+AK
Sbjct: 548 PEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAK 607
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
DLL+ L R+P++RLG G +I+ HP F +++W+ L+ K PP++P V D SNFD
Sbjct: 608 DLLVKLFVREPEKRLGVRG--DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
Query: 669 QEFTREQPVDSVVNDFLSESVQQ 691
+EF E+P S + L S+ Q
Sbjct: 666 KEFLNEKPRLSFADRALINSMDQ 688
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 303 bits (776), Expect = 6e-82
Identities = 147/302 (48%), Positives = 207/302 (67%), Gaps = 2/302 (0%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
K +++++F+ LKV+GKG+FGKV+ R++ T K+YA+K ++K I+ K EV HTL E VL
Sbjct: 178 KKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL 237
Query: 435 ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
++PF++ LK+SFQ++++L V+ ++NGGELF+HL E F R+RFY AE++ AL
Sbjct: 238 KSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALG 297
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
LH IIYRDLK EN+LLD GHI + DFGLCK ++ T TFCGTPEYLAPE+L
Sbjct: 298 YLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDD 357
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGL 614
Y + VDWW GV++YEM+ G P+Y+ D ++ IL + ++FP + +AK+LL GL
Sbjct: 358 NDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGL 417
Query: 615 LCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFT 672
L +DPK+RLG D EI++HPFF ++W L +K PP+KP V DT FD+EFT
Sbjct: 418 LAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFT 477
Query: 673 RE 674
E
Sbjct: 478 GE 479
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 303 bits (775), Expect = 8e-82
Identities = 149/325 (45%), Positives = 222/325 (67%), Gaps = 4/325 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ I+DF++LKV+G+G+FGKV QVRK+DT++IYA+K +RK IV K+ + AER +L +
Sbjct: 135 VGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTK 194
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+D+PFIV LK+SFQ+ +LYLVL FINGG LF+ L +G F +R YTAE++ A+ L
Sbjct: 195 IDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHL 254
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H+ I++RDLKPENIL+D GH+ L DFGL K ++ ++ + CGT EY+APE++ G+G
Sbjct: 255 HEKGIMHRDLKPENILMDVDGHVMLTDFGLAK-EFEENTRSNSMCGTTEYMAPEIVRGKG 313
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
+ K DWW++G+LLYEMLTG PP+ K+ +KI++D ++ P +A LL GLL
Sbjct: 314 HDKAADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHALLKGLLQ 372
Query: 617 RDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
++P+RRLG G++EIK H +F ++WK+L+ + P +KP V G +NFD+ +T
Sbjct: 373 KEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFDKCWTDM 432
Query: 675 QPVDSVVNDFLSESVQQQFGGWTYV 699
+DS + S++ F +TYV
Sbjct: 433 SVLDSPASSPNSDAKANPFTNFTYV 457
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 300 bits (768), Expect = 5e-81
Identities = 165/340 (48%), Positives = 219/340 (63%), Gaps = 7/340 (2%)
Query: 382 FDLLKVIGKGSFGKVMQVRK-RDTN--KIYALKAIRKSYIVSKSEVT-HTLAERTVLARV 437
F+LL+V+GKG +GKV QVRK + TN KIYA+K +RK+ IV ++ T HT AER +L V
Sbjct: 80 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 139
Query: 438 DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
+PFIV L ++FQ+ KLYL+L ++GGELF HL+REG F + FY AE+ AL LH
Sbjct: 140 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 199
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGY 557
IIYRDLKPENI+L QGHI L DFGLCK ++ + T TFCGT EY+APE+L+ G+
Sbjct: 200 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 259
Query: 558 TKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
+ VDWW+LG L+Y+MLTG PP+ E+ K KI++ L P DA+DL+ L R
Sbjct: 260 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 319
Query: 618 DPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQ 675
+P +R+G D +++ HPFF ++W L PP++P + D S FD FTR+
Sbjct: 320 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQT 379
Query: 676 PVDSVVNDFLSESVQQQFGGWTYVGSEQLGQSMLPDRSFQ 715
PVDS + LSES Q F G+TYV L S+ SFQ
Sbjct: 380 PVDSPDDTALSESANQAFLGFTYVAPSVL-DSIKEGFSFQ 418
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 298 bits (763), Expect = 2e-80
Identities = 152/327 (46%), Positives = 208/327 (63%), Gaps = 14/327 (4%)
Query: 364 NLSVDYKPST-----------HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKA 412
N S+D++ S ++++DFD LKV+GKG+FGKV+ +++ T K+YA+K
Sbjct: 164 NCSIDFRASMISIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKI 223
Query: 413 IRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQ 472
++K I+++ EV HTL E VL R +PF+ LK+SFQ L V+ F NGGELF H++
Sbjct: 224 LKKDVIIAREEVAHTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVR 283
Query: 473 REGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMK 532
+ G F R+RFY AE++ AL LH DI+YRD+K EN+LLD GHI + DFGLCK +
Sbjct: 284 KCGTFSEPRARFYGAEIVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEIS 343
Query: 533 DQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKI 592
+KT+TFCGTPEYLAPE+L Y + VDWW +GV++YEM+ G P+Y +D K+++ I
Sbjct: 344 FGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELI 403
Query: 593 LQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGY 650
+ LRFP ++A+ LL GLL +DP +RLG D EI FF + W+ K
Sbjct: 404 MAGDLRFPSKLSQEARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEI 463
Query: 651 IPPYKPPVMGAMDTSNFDQEFTREQPV 677
PPYKP V DTS FD EFT QPV
Sbjct: 464 EPPYKPNVQSETDTSYFDNEFT-SQPV 489
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 297 bits (760), Expect = 4e-80
Identities = 146/304 (48%), Positives = 207/304 (68%), Gaps = 4/304 (1%)
Query: 375 KH-LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
KH +++++F+ LK++GKG+FGKV+ V+++ T + YA+K ++K IV+K EV HTL E V
Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
L +PF+ LK+SFQ+ ++L V+ + NGGELF+HL RE F R+RFY AE++ AL
Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261
Query: 494 EALH-DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELL 552
+ LH + +++YRDLK EN++LD GHI + DFGLCK +KD TFCGTPEYLAPE+L
Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL 321
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
Y + VDWW LGV++YEM+ G P+Y++D K+++ IL + +RFP +AK LL
Sbjct: 322 EDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 381
Query: 613 GLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQE 670
GLL +DPK+RLG D EI H FF + W+ + K PP+KP V DT FD+E
Sbjct: 382 GLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEE 441
Query: 671 FTRE 674
FT +
Sbjct: 442 FTAQ 445
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 297 bits (760), Expect = 4e-80
Identities = 157/325 (48%), Positives = 213/325 (65%), Gaps = 6/325 (1%)
Query: 381 DFDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVT-HTLAERTVLAR 436
DF+L KV+GKG +GKV QVRK RD NK +A+K ++K+ IV+ + T HT AER +L
Sbjct: 76 DFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEA 135
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
V +PFIV L ++FQ+ KLYL+L +++GGELF HL+REG F + FY +E++ AL L
Sbjct: 136 VKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHL 195
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H IIYRDLKPENILLD QGH+ L DFGLCK ++++ T TFCGT EY+APE+L G
Sbjct: 196 HKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSG 255
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
+ K VDWW+LG L+++MLTG+PP+ E+ K + IL+ L P +A+DL+ L+
Sbjct: 256 HGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEARDLVRRLMK 315
Query: 617 RDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
R +RLG D ++ HPFF ++W + + PP KP + D S FD FTR+
Sbjct: 316 RQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQ 375
Query: 675 QPVDSVVNDFLSESVQQQFGGWTYV 699
PVDS + LSES F G+TYV
Sbjct: 376 IPVDSPDDTTLSESANLIFQGFTYV 400
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 296 bits (757), Expect = 1e-79
Identities = 140/334 (41%), Positives = 218/334 (64%), Gaps = 6/334 (1%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
K L +D+F+ +KV+GKGSFGKVM + +++YA+K ++K I+ +V T+ E+ +L
Sbjct: 401 KRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRIL 460
Query: 435 ARV-DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
A +P++ L FQ+ ++L+ V+ ++NGG+L + +QR +FD RSRFY AE+ AL
Sbjct: 461 ALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSAL 520
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLL 553
LH +IYRDLK +NILLD +GH L DFG+CK + + TTTFCGTP+Y+APE+L
Sbjct: 521 MFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQ 580
Query: 554 GQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIG 613
Y VDWW LGVL+YEM+ G PP+ ++ +++ IL D + +P K+A +L
Sbjct: 581 ELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKA 640
Query: 614 LLCRDPKRRLG----YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
+ ++P +RLG +G D IK HPFF ++ W L+ K PP+KP + D +NFDQ
Sbjct: 641 FMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQ 700
Query: 670 EFTREQPVDSVVNDFLSESV-QQQFGGWTYVGSE 702
+FTRE+PV ++V++ + + + Q++F G++Y G +
Sbjct: 701 DFTREEPVLTLVDEAIVKQINQEEFKGFSYFGED 734
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 295 bits (754), Expect = 2e-79
Identities = 139/325 (42%), Positives = 216/325 (65%), Gaps = 3/325 (0%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV 437
S+ DF+ +KV+GKGSFGKVM K+ T++IYA+K ++K I+ +V T+ E+ +LA
Sbjct: 404 SLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALA 463
Query: 438 DN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
N PF+ L FQ+ ++L+ V+ ++NGG+L + +Q+ RF+ SR+ FY AE+ AL+ L
Sbjct: 464 ANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFL 523
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +IYRDLK +NILLD +GH L DFG+CK + + TTTFCGTP+Y+APE+L Q
Sbjct: 524 HTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQE 583
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
Y VDWW LGVL+YEM+ G PP+ ++ +++ I+ D + +P ++A +L G L
Sbjct: 584 YGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLT 643
Query: 617 RDPKRRLGYHGSD-EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQ 675
++P++RLG G + EI+ HPFF +L WK L+ + PP++P + D +NFD EFT+E
Sbjct: 644 KNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKED 703
Query: 676 PVDSVVNDFLSESV-QQQFGGWTYV 699
PV + + + + + Q +F G+++V
Sbjct: 704 PVLTPIGNEVVRCINQDEFAGFSFV 728
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 293 bits (751), Expect = 5e-79
Identities = 138/329 (41%), Positives = 217/329 (65%), Gaps = 6/329 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA- 435
LSI DF +KV+GKGSFGKVM ++ T+++YA+K ++K IV +V T+ E+ +L+
Sbjct: 373 LSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSL 432
Query: 436 RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
+PF+ L SFQ+S++L+ V+ ++NGG+L + +QR +FD SR+RFY AE+ CAL+
Sbjct: 433 AAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQF 492
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
LH D+IYRDLK +NILLD +GH L DFG+CK + T+TFCGTP+Y+APE+L
Sbjct: 493 LHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEM 552
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y VDWW LGVL+YEM+ G PP+ ++ +++ IL D + +P K+A ++L +
Sbjct: 553 EYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFM 612
Query: 616 CRDPKRRLG----YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEF 671
++ +RLG G D I++HPFF ++ W L+ + PP+KP + D +NFD +F
Sbjct: 613 TKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDF 672
Query: 672 TREQPVDSVVNDFLSESV-QQQFGGWTYV 699
T+E+PV + + + ++ Q +F G++++
Sbjct: 673 TKEEPVLTPSDPAVVRAINQDEFRGFSFI 701
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 292 bits (748), Expect = 1e-78
Identities = 157/331 (47%), Positives = 211/331 (63%), Gaps = 6/331 (1%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKR---DTNKIYALKAIRKSYIV-SKSEVTHTLAERTVLA 435
+DF LLKV+GKG +GKV QVRK D +I+A+K ++K+ IV ++ + HT AER +L
Sbjct: 81 EDFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNILE 140
Query: 436 RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
V +PFI L ++FQ+ KLYL+L +++GGELF HL+REG F + ++FY +E++ +LE
Sbjct: 141 AVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEH 200
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
LH IIYRDLKPENILLD GH+ L DFGLCK ++ +KT TFCGT EY+APE+L+
Sbjct: 201 LHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMRC 260
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
G+ K VDWW+LG L+++MLTG PP+ E+ K KIL+ L P +A+DL+ LL
Sbjct: 261 GHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKLL 320
Query: 616 CRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTR 673
R RLG SD EIKSH FF W + + P+KP + DTS FD FT+
Sbjct: 321 KRHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDEDTSLFDARFTK 380
Query: 674 EQPVDSVVNDFLSESVQQQFGGWTYVGSEQL 704
PVDS S + F G+TYV L
Sbjct: 381 MTPVDSPCETNFSLNGDNPFVGFTYVAPSVL 411
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 292 bits (748), Expect = 1e-78
Identities = 151/332 (45%), Positives = 211/332 (63%), Gaps = 19/332 (5%)
Query: 364 NLSVDYKPST-----------HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKA 412
N S+D++ S ++++DFD LKV+GKG+FGKV+ +++ T K+YA+K
Sbjct: 164 NCSIDFRASMISIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKI 223
Query: 413 IRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQ 472
++K I+++ EV HTL E VL R +PF+ LK+SFQ++++L V+ F GG+L+YHL
Sbjct: 224 LKKDVIIAREEVAHTLTENRVLQRCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLN 283
Query: 473 REGR-----FDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLC 527
RE + F R+RFY +E++ AL LH I+YRDLK EN+LLD GHI + DFGLC
Sbjct: 284 REVQMNKEGFSEPRARFYGSEIVLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLC 343
Query: 528 KLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPK 587
K + +KT+TFCGTPEYLAPE+L Y + VDWW +GV++YEM+ G P+Y +D K
Sbjct: 344 KEEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNK 403
Query: 588 MYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRL 645
+++ I+ LRFP ++A+ LL GLL +DP +RLG D EI FF + W+
Sbjct: 404 LFELIMAGDLRFPSKLSQEARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEAT 463
Query: 646 KMKGYIPPYKPPVMGAMDTSNFDQEFTREQPV 677
K PPYKP V DTS FD EFT QPV
Sbjct: 464 YRKEIEPPYKPNVQSETDTSYFDNEFT-SQPV 494
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 290 bits (742), Expect = 5e-78
Identities = 157/404 (38%), Positives = 238/404 (58%), Gaps = 22/404 (5%)
Query: 302 NWQETQISNNDILGDYVKKIRNNSDIHLDSFHLPLNLKIDSASNIRLYNHHWIELESKMG 361
N + T +S+N LG V+ + D D+ P +L ++ +
Sbjct: 615 NLEVTSVSDNK-LGATVQVVEQKVDDKADALTKPPSLDA-------------VKEPIPVP 660
Query: 362 KLNLSVDYKPSTHK--HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIV 419
+ SV + THK + ++DF L V+GKG+FGKVM + ++YA+K ++K +I+
Sbjct: 661 SVETSVVAQDLTHKAKRIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFIL 720
Query: 420 SKSEVTHTLAERTVLA---RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR 476
EV T +E+ V R +PF+V L FQ+ ++Y V+ F++GG+L H+Q+E +
Sbjct: 721 ENDEVESTKSEKRVFLVANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-Q 779
Query: 477 FDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEK 536
F R++FY AE+ AL+ HD IIYRDLK +NILL GH+ + D+GLCK +M
Sbjct: 780 FSRRRAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNT 839
Query: 537 TTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDP 596
T TFCGTPE++APE+LL Q YT+ VDWW GVL+Y+ML G P+ ED +++ IL D
Sbjct: 840 TATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDE 899
Query: 597 LRFPDDFDKDAKDLLIGLLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPY 654
+P +D+ +L LL RDPK+RLG + ++++ +HPFF+ ++W + K PPY
Sbjct: 900 PLYPIHMPRDSVSILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPY 959
Query: 655 KPPVMGAMDTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTY 698
P + DT FD+EFTRE PV + VN L++ +QQ F G++Y
Sbjct: 960 IPSLNSPTDTKYFDEEFTRELPVLTPVNSILTKEMQQHFEGFSY 1003
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 285 bits (728), Expect = 2e-76
Identities = 141/324 (43%), Positives = 212/324 (64%), Gaps = 4/324 (1%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA-R 436
+I++F KV+GKGSFGKV+ + + +A+KA++K ++ +V T+ E+ VL
Sbjct: 345 NINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLA 404
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+NPF+ L +FQ+ + L+ V+ F+NGG+L YH+Q +GRF+L R+ FY AE++C L+ L
Sbjct: 405 AENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFL 464
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H IIYRDLK +N+LLD GHI + DFG+CK N+ + + +TFCGTP+Y+APE+L G
Sbjct: 465 HSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLK 524
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
YT VDWW+ GVLLYEML G P++ +D ++++ I D +P K++KD+L L
Sbjct: 525 YTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFE 584
Query: 617 RDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQP 676
R+P +RLG G+ IK HPFF ++W L+ + PP++P V D SNFDQEF E+
Sbjct: 585 REPTKRLGVTGN--IKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKA 642
Query: 677 VDSVVNDFLSESVQQQ-FGGWTYV 699
S + L +S+ Q F G+++V
Sbjct: 643 RLSYSDKNLIDSMDQSAFAGFSFV 666
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 283 bits (723), Expect = 8e-76
Identities = 141/324 (43%), Positives = 211/324 (64%), Gaps = 4/324 (1%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA-R 436
+I++F KV+GKGSFGKV+ + + A+KA++K ++ +V T+ E+ VL
Sbjct: 345 NINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRVLTLA 404
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+NPF+ L +FQ+ + L+ V+ F+NGG+L YH+Q +GRF+L R+ FY AE++C L+ L
Sbjct: 405 AENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFL 464
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H IIYRDLK +N+LLD GHI + DFG+CK N+ + + +TFCGTP+Y+APE+L G
Sbjct: 465 HSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLK 524
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
YT VDWW+ GVLLYEML G P++ +D ++++ I D +P K++KD+L L
Sbjct: 525 YTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFE 584
Query: 617 RDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQP 676
R+P +RLG G+ IK HPFF ++W L+ + PP++P V D SNFDQEF E+
Sbjct: 585 REPTKRLGMTGN--IKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKA 642
Query: 677 VDSVVNDFLSESVQQQ-FGGWTYV 699
S + L +S+ Q F G+++V
Sbjct: 643 RLSYSDKNLIDSMDQSAFAGFSFV 666
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 281 bits (720), Expect = 2e-75
Identities = 138/336 (41%), Positives = 212/336 (63%), Gaps = 5/336 (1%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
++ L ID+F+ ++V+GKGSFGKVM R ++T +YA+K ++K I+ +V T+ E+
Sbjct: 344 NSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEK 403
Query: 432 TVLARVDN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+L+ N PF+ L FQ+ ++L+ V+ F+NGG+L +H+Q+ RFD +R+RFY AE++
Sbjct: 404 RILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEII 463
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
AL LHD IIYRDLK +N+LLD++GH L DFG+CK + + T TFCGTP+Y+APE
Sbjct: 464 SALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPE 523
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
+L Y VDWW +GVLLYEML G P+ E+ +++ IL D + +P +DA +
Sbjct: 524 ILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGI 583
Query: 611 LIGLLCRDPKRRLG---YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNF 667
L + ++P RLG G I HPFF ++ W +L + PP++P + D SNF
Sbjct: 584 LKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNF 643
Query: 668 DQEFTREQPVDSVVND-FLSESVQQQFGGWTYVGSE 702
D +F +E+PV + +++ L Q +F ++YV E
Sbjct: 644 DPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPE 679
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 281 bits (720), Expect = 2e-75
Identities = 136/330 (41%), Positives = 211/330 (63%), Gaps = 5/330 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ + DF+ L V+GKGSFGKVM ++ T ++YA+K ++K ++ +V T+ E+ VLA
Sbjct: 334 VKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLAL 393
Query: 437 VDNP-FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
+D P F+ L FQ+ ++LY V+ ++NGG+L YH+Q+ G+F ++ FY AE+ L
Sbjct: 394 LDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFF 453
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
LH IIYRDLK +N++LD +GHI + DFG+CK +M D T TFCGTP+Y+APE++ Q
Sbjct: 454 LHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQ 513
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y K VDWW GVLLYEML G PP+ ED ++++ I++ + +P K+A + GL+
Sbjct: 514 PYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLM 573
Query: 616 CRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTR 673
+ P +RLG G +++ H FF ++ W++L+ + PP+KP V G NFD+ FTR
Sbjct: 574 TKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTR 632
Query: 674 EQPVDSVVNDFLSESV-QQQFGGWTYVGSE 702
QPV + + + ++ Q F G++YV +
Sbjct: 633 GQPVLTPPDQLVIANIDQSDFEGFSYVNPQ 662
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 281 bits (718), Expect = 3e-75
Identities = 142/298 (47%), Positives = 198/298 (65%), Gaps = 2/298 (0%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+++DDFD LKV+G+G+FGKV+ R++ ++K+YA+K IRK +V +SEV HTL E VL
Sbjct: 175 VTMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYA 234
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+PF+ LK+SFQ+ + V+ F NGGELF HLQR F +R+RFY +E++ AL L
Sbjct: 235 CVHPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYL 294
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +I+YRD+K EN+LLD GHI + DFGLCK +K +KT+TFCGTPEYLAPE++
Sbjct: 295 HHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDID 354
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
Y + VDWW +GV++YEM+ G P+ ++ K+++ I L+FP+ +A LL GLL
Sbjct: 355 YDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVTLLSGLLE 414
Query: 617 RDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFT 672
R P +RLG D E+ FF + W+ K PP+KP VM DTS FD+EFT
Sbjct: 415 RVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFFDREFT 472
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 278 bits (711), Expect = 2e-74
Identities = 133/329 (40%), Positives = 208/329 (62%), Gaps = 10/329 (3%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DF+ +KV+GKGSFGKV+ ++ + ++YA+K ++K I+ +V T+ E+ VLA + P
Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408
Query: 441 -FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
F+V L FQ+ ++L+ V+ ++NGG+L + +Q+ G+F + FY AE+ L LH
Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTK 559
I+YRDLK +N+LLD GH+ + DFG+CK N+ + T TFCGTP+Y+APE++L Q Y K
Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGK 528
Query: 560 VVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDP 619
VDWW GVLLYEML G PP+ ED +++ I + +P K+AK+ G L + P
Sbjct: 529 SVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQP 588
Query: 620 KRRL--GYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQ-- 675
+RL G G ++++ HPFF ++ W++++ + PP+KP + D SNFD++FT E+
Sbjct: 589 NKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTD 648
Query: 676 --PVDSVVNDFLSESVQQQFGGWTYVGSE 702
P D V F+ Q +F G++Y+ E
Sbjct: 649 LTPTDKV---FMMNLDQSEFVGFSYMNPE 674
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 276 bits (707), Expect = 6e-74
Identities = 138/332 (41%), Positives = 208/332 (62%), Gaps = 5/332 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ + DF+ L V+GKGSFGKVM ++ T+++YA+K ++K ++ +V T+ E+ VLA
Sbjct: 337 MKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLAL 396
Query: 437 VDNP-FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
P F+ L FQ+ ++LY V+ ++NGG+L YH+Q+ GRF + FY AE+ L
Sbjct: 397 PGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFF 456
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
L IIYRDLK +N++LD +GHI + DFG+CK N+ D T TFCGTP+Y+APE++ Q
Sbjct: 457 LQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQ 516
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y K VDWW GVLLYEML G P+ ED ++++ I++ + +P K+A + GL+
Sbjct: 517 PYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLM 576
Query: 616 CRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTR 673
+ P +RLG G +IK H FF + W++L+ K PPYKP G + NFD+ FTR
Sbjct: 577 TKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACG-RNAENFDRFFTR 635
Query: 674 EQPVDSVVNDFLSESV-QQQFGGWTYVGSEQL 704
PV + + + ++ Q +F G+++V SE L
Sbjct: 636 HPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFL 667
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 276 bits (707), Expect = 6e-74
Identities = 138/332 (41%), Positives = 208/332 (62%), Gaps = 5/332 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ + DF+ L V+GKGSFGKVM ++ T+++YA+K ++K ++ +V T+ E+ VLA
Sbjct: 337 MKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLAL 396
Query: 437 VDNP-FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
P F+ L FQ+ ++LY V+ ++NGG+L YH+Q+ GRF + FY AE+ L
Sbjct: 397 PGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFF 456
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
L IIYRDLK +N++LD +GHI + DFG+CK N+ D T TFCGTP+Y+APE++ Q
Sbjct: 457 LQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQ 516
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y K VDWW GVLLYEML G P+ ED ++++ I++ + +P K+A + GL+
Sbjct: 517 PYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLM 576
Query: 616 CRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTR 673
+ P +RLG G +IK H FF + W++L+ K PPYKP G + NFD+ FTR
Sbjct: 577 TKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACG-RNAENFDRFFTR 635
Query: 674 EQPVDSVVNDFLSESV-QQQFGGWTYVGSEQL 704
PV + + + ++ Q +F G+++V SE L
Sbjct: 636 HPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFL 667
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 276 bits (706), Expect = 8e-74
Identities = 133/292 (45%), Positives = 188/292 (63%), Gaps = 5/292 (1%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+DDFD +K +G GSFG+VM V+ + + YA+K + K +V +V HTL E+ +L +D
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAID 108
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
PF+V + FSF+ + LY+VL FI+GGE+F HL+R GRF SRFY A+++ A E LH
Sbjct: 109 FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHS 168
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
D+IYRDLKPEN+L+D G++ + DFG K + + +T T CGTPEYLAPE++L +GY
Sbjct: 169 LDLIYRDLKPENLLIDSTGYLKITDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYN 225
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
K VDWW LGVL+YEM G PP++ + ++Y+KI+ ++FP F + KDLL LL D
Sbjct: 226 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVD 285
Query: 619 PKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
+R G +G +IK+H +F W + K P+ P G D SNFD
Sbjct: 286 LTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFD 337
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 275 bits (702), Expect = 2e-73
Identities = 150/346 (43%), Positives = 208/346 (59%), Gaps = 8/346 (2%)
Query: 364 NLSVDYKPSTHK--HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSK 421
N SV P K +++DDF L V+GKG+FGKVM + K YA+K ++K I+
Sbjct: 552 NRSVPESPRREKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKN 611
Query: 422 SEVTHTLAERTVLA---RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFD 478
E+ E+ V + +PF++ L SFQ+S ++Y V+ +I GG+L H+QR+ +F
Sbjct: 612 EELESLKTEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQ-QFS 670
Query: 479 LSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTT 538
+ R+RFY AE+ AL+ H+ I YRDLK +NILL GHI + D+GLCK NM T+
Sbjct: 671 VKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTS 730
Query: 539 TFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLR 598
TFCGTPE++APE+LL Q Y+K VDWW GVL+Y+ML G P+ ED +++ IL D
Sbjct: 731 TFCGTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPL 790
Query: 599 FPDDFDKDAKDLLIGLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKP 656
FP + DA LL GLL RDP +RLG D E+ +HPFF + W L K Y P YKP
Sbjct: 791 FPINMPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKP 850
Query: 657 PVMGAMDTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYVGSE 702
+ D +NFD+EFT P + VN L+ Q+ F G++ +E
Sbjct: 851 LINDPRDLNNFDEEFTSACPTLTPVNTVLTRQQQECFRGFSSFATE 896
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 275 bits (702), Expect = 2e-73
Identities = 139/295 (47%), Positives = 195/295 (65%), Gaps = 2/295 (0%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+++DDFD LKV+G+G+FGKV+ R++ ++K+YA+K IRK +V +SEV HTL E VL
Sbjct: 175 VTMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYA 234
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+PF+ LK+SFQ+ + V+ F NGGELF HLQR F +R+RFY +E++ AL L
Sbjct: 235 CVHPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYL 294
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +I+YRD+K EN+LLD GHI + DFGLCK +K +KT+TFCGTPEYLAPE++
Sbjct: 295 HHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDID 354
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
Y + VDWW +GV++YEM+ G P+ ++ K+++ I L+FP+ +A LL GLL
Sbjct: 355 YDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVTLLSGLLE 414
Query: 617 RDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
R P +RLG D E+ FF + W+ K PP+KP VM DTS FD+
Sbjct: 415 RVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFFDR 469
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 274 bits (701), Expect = 3e-73
Identities = 131/292 (44%), Positives = 190/292 (64%), Gaps = 5/292 (1%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+D F+ +K +G GSFG+VM V+ ++T YA+K + K +V ++ HTL E+ +L V+
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
PF+V L+FSF+ + LY+V+ ++ GGE+F HL+R GRF +RFY A+++ E LH
Sbjct: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
D+IYRDLKPEN+L+D QG+I + DFG K + + +T T CGTPEYLAPE++L +GY
Sbjct: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYN 217
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
K VDWW LGVL+YEM G PP++ + ++Y+KI+ +RFP F D KDLL LL D
Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277
Query: 619 PKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
+R G +G ++IK+H +F W + + P+ P G DTSNFD
Sbjct: 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 274 bits (700), Expect = 4e-73
Identities = 130/298 (43%), Positives = 193/298 (64%), Gaps = 5/298 (1%)
Query: 373 THKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERT 432
T + ++DF+ K +G GSFG+VM V+ + T + YA+K + K +V ++ HTL E+
Sbjct: 35 TQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKR 94
Query: 433 VLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
+L V+ PF+V L+++F+ + LY+V+ ++ GGE+F HL+R GRF +RFY A+++
Sbjct: 95 ILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELL 552
E LH D+IYRDLKPEN+L+D+QG+I + DFG K + + +T T CGTPEYLAPE++
Sbjct: 155 FEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEII 211
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
L +GY K VDWW LGVL+YEM G PP++ + ++Y+KI+ +RFP F D KDLL
Sbjct: 212 LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 271
Query: 613 GLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
LL D +R G +G +IK+H +F W + + P+ P G+ DTSNFD
Sbjct: 272 NLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFD 329
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 272 bits (695), Expect = 1e-72
Identities = 138/306 (45%), Positives = 201/306 (65%), Gaps = 7/306 (2%)
Query: 367 VDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTH 426
+ Y+ ++ K+ S+ DF +L+ +G GSFG+V +R + YALK ++K IV +V H
Sbjct: 74 LQYRDTSGKY-SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEH 132
Query: 427 TLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYT 486
T ER +L+ V +PFI+ + +FQ S+++++V+ +I GGELF L++ RF ++FY
Sbjct: 133 TNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 192
Query: 487 AELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEY 546
AE+ ALE LH DIIYRDLKPENILLD GHI + DFG K + T T CGTP+Y
Sbjct: 193 AEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKY---VPDVTYTLCGTPDY 249
Query: 547 LAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKD 606
+APE++ + Y K VDWW+ GVL+YEML G P+Y+ + K Y+ IL L+FP F D
Sbjct: 250 IAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPD 309
Query: 607 AKDLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV-MGAMD 663
A+DLL L+ RD RLG +GS+++K+HP+FN++ W++L + PY+PP+ G D
Sbjct: 310 AQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGD 369
Query: 664 TSNFDQ 669
TS FD+
Sbjct: 370 TSQFDR 375
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 271 bits (693), Expect = 3e-72
Identities = 142/376 (37%), Positives = 220/376 (57%), Gaps = 18/376 (4%)
Query: 341 DSASNIRLYNHHWIELESKMGKLNLSVDYKPS--THKHLSIDDFDLLKVIGKGSFGKVMQ 398
D A + YN E ++G+ +++ + S L + DFDLL+VIG+GS+ KV+
Sbjct: 202 DHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLL 261
Query: 399 VRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN-PFIVPLKFSFQSSEKLYL 457
VR + T++IYA+K ++K + ++ E+ V + N PF+V L FQ+ +L+
Sbjct: 262 VRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFF 321
Query: 458 VLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQG 517
V+ ++NGG+L +H+QR+ + +RFY+AE+ AL LH+ IIYRDLK +N+LLD +G
Sbjct: 322 VIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEG 381
Query: 518 HIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGL 577
HI L D+G+CK ++ + T+TFCGTP Y+APE+L G+ Y VDWW LGVL++EM+ G
Sbjct: 382 HIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGR 441
Query: 578 PPY---YDEDVPK------MYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYH-- 626
P+ D P +++ IL+ +R P A +L L +DPK RLG H
Sbjct: 442 SPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQ 501
Query: 627 -GSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDSVV--ND 683
G +I+ HPFF + W ++ K +PP+KP + G NFD +FT E PV +D
Sbjct: 502 TGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNE-PVQLTPDDDD 560
Query: 684 FLSESVQQQFGGWTYV 699
+ + Q +F G+ Y+
Sbjct: 561 IVRKIDQSEFEGFEYI 576
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 271 bits (693), Expect = 3e-72
Identities = 150/344 (43%), Positives = 212/344 (61%), Gaps = 16/344 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVT-HTLAERT 432
+S++DF +++V+G G++G+V VRK D K+YA+K + K +V K + HT ER
Sbjct: 256 VSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERV 315
Query: 433 VLARVD-NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
VL + NPF+V L ++FQSS KLYLVL F NGGELF HL F+ SR R Y AE++
Sbjct: 316 VLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVL 375
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK-LNMKDQEKTTTFCGTPEYLAPE 550
ALE LH IIYRD+K ENILLD +GHI L DFGL K L +++ + +FCGT EY+APE
Sbjct: 376 ALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPE 435
Query: 551 LLL--GQGYTKVVDWWTLGVLLYEMLTGLPPYYDED----VPKMYKKILQDPLRFPDDFD 604
++ G+ VDWW++GVL +E+LTG P+ D ++ ++I ++ P F
Sbjct: 436 IIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFS 495
Query: 605 KDAKDLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
+A+D ++ +L ++PKRRLG + + EIK HPFFN ++W+ L+ K PYKP +
Sbjct: 496 ANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAED 555
Query: 663 DTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYVGSEQLGQ 706
D NF EFT + P D + S + F G+TYV E L Q
Sbjct: 556 DVQNFSNEFTDQVPEDPECD--APPSRIRLFRGYTYVAPEHLEQ 597
Score = 63.5 bits (153), Expect = 1e-09
Identities = 60/208 (28%), Positives = 94/208 (44%), Gaps = 16/208 (7%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
DD +L G++G V T+ ++ K I S SEV ++ L ++
Sbjct: 621 DDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKF-RPSEVDALIS--CALDTTNH 677
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
IV +F+ + ++V+ +++G EL + R D R +L+ A+ +H
Sbjct: 678 KNIVSYHGTFREKCETWIVMEYLSGPELTASI----RMDEDSCREIFLQLVMAVRHIHSK 733
Query: 500 DIIYRDLKPENILLDYQGH--IALCDFGLCKLN-----MKDQEKTTTFCGTPEYLAPELL 552
I+ DLKPENI+ + + + L DFG N KD+ + T PE LA L
Sbjct: 734 HFIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRYTLDYAPPEMLADANL 793
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPY 580
+ Y+ VD + LG LY ML G PY
Sbjct: 794 V--TYSPAVDIYGLGATLYTMLVGHRPY 819
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 270 bits (689), Expect = 7e-72
Identities = 130/292 (44%), Positives = 195/292 (66%), Gaps = 6/292 (2%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
+F +L+ +G GSFG+V +R R + YA+K ++K +V +V HT ER +L+ V +P
Sbjct: 86 NFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHP 145
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
FI+ + +FQ ++++++++ +I GGELF L++ RF ++FY AE+ ALE LH D
Sbjct: 146 FIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD 205
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKV 560
IIYRDLKPENILLD GHI + DFG K + T T CGTP+Y+APE++ + Y K
Sbjct: 206 IIYRDLKPENILLDKNGHIKITDFGFAKY---VPDVTYTLCGTPDYIAPEVVSTKPYNKS 262
Query: 561 VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPK 620
+DWW+ G+L+YEML G P+YD + K Y+KIL LRFP F++D KDLL L+ RD
Sbjct: 263 IDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLS 322
Query: 621 RRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV-MGAMDTSNFDQ 669
+RLG +G++++K+HP+F ++ W++L + PY+PP+ G DTS FD+
Sbjct: 323 QRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDK 374
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 270 bits (689), Expect = 7e-72
Identities = 139/344 (40%), Positives = 208/344 (60%), Gaps = 14/344 (4%)
Query: 370 KPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA 429
+P T + S++DF+L++VIG+GS+ KV+ V R T +IYA+K I+K+ + ++
Sbjct: 249 EPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQT 308
Query: 430 ERTVLARVDN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAE 488
E+ V N PF+V L FQ+ +L+ V+ F+ GG+L YH+QR+ R +RFY AE
Sbjct: 309 EKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAE 368
Query: 489 LLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLA 548
+ AL LH+ IIYRDLK +N+LLD++GHI L D+G+CK ++ + T+TFCGTP Y+A
Sbjct: 369 ISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIA 428
Query: 549 PELLLGQGYTKVVDWWTLGVLLYEMLTGLPPY--------YDEDVPK-MYKKILQDPLRF 599
PE+L G+ Y VDWW LGVLLYEML G P+ D++ +++ IL+ +R
Sbjct: 429 PEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRI 488
Query: 600 PDDFDKDAKDLLIGLLCRDPKRRLGYHGSD---EIKSHPFFNQLSWKRLKMKGYIPPYKP 656
P A +L G L ++P RLG H +I SHPFF + W+ L+ K PP+KP
Sbjct: 489 PRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKP 548
Query: 657 PVMGAMDTSNFDQEFTREQPVDSVVNDFLSESV-QQQFGGWTYV 699
+ D +NF EFT E + +D + +++ Q +F G+ YV
Sbjct: 549 RLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYV 592
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 269 bits (688), Expect = 1e-71
Identities = 148/337 (43%), Positives = 214/337 (62%), Gaps = 16/337 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVT-HTLAERT 432
+ I++F+LLKV+G G++GKV VRK DT K+YA+K ++K+ IV K++ T HT ER
Sbjct: 44 VGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQ 103
Query: 433 VLARV-DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
VL + +PF+V L ++FQ+ KL+L+L +INGGELF HL + RF + Y E++
Sbjct: 104 VLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVL 163
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQ-EKTTTFCGTPEYLAPE 550
ALE LH IIYRD+K ENILLD GH+ L DFGL K + D+ E+ +FCGT EY+AP+
Sbjct: 164 ALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPD 223
Query: 551 LLLG--QGYTKVVDWWTLGVLLYEMLTGLPPY----YDEDVPKMYKKILQDPLRFPDDFD 604
++ G G+ K VDWW+LGVL+YE+LTG P+ ++ ++IL+ +P +
Sbjct: 224 IVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMS 283
Query: 605 KDAKDLLIGLLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
AKDL+ LL +DPK+RLG +DEIK H FF +++W L K P+KP + +
Sbjct: 284 ALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDEL 343
Query: 663 DTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYV 699
D SNF +EFT P S L +S ++ F G+++V
Sbjct: 344 DVSNFAEEFTEMDPTYSPA--ALPQSSEKLFQGYSFV 378
Score = 128 bits (321), Expect = 3e-29
Identities = 88/269 (32%), Positives = 135/269 (49%), Gaps = 23/269 (8%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
++H +D D K +G+GSF + + +N+ +K I+SK +T E T
Sbjct: 420 YQHYDLDLKD--KPLGEGSFSICRKCVHKKSNQALQVK------IISKRMEANTQKEITA 471
Query: 434 LARVD-NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
L + +P IV L F +LV+ +NGGELF L+++ F + + + +L+ A
Sbjct: 472 LKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSA 531
Query: 493 LEALHDFDIIYRDLKPENILLDYQG---HIALCDFGLCKLNMKDQEKTTTFCGTPEYLAP 549
L +HD +++RDLKPEN+L + I + DFG +L D + T C T P
Sbjct: 532 LSHMHDLGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRP 591
Query: 550 ELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDED-------VPKMYKKILQDPLRFPDD 602
ELL GY + D W+LGV+LY ML+G P+ D ++ KKI + F +
Sbjct: 592 ELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGE 651
Query: 603 ----FDKDAKDLLIGLLCRDPKRRLGYHG 627
++AKDL+ GLL DP +RL G
Sbjct: 652 AWKNVSQEAKDLIQGLLTVDPNKRLKMSG 680
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 269 bits (688), Expect = 1e-71
Identities = 136/319 (42%), Positives = 196/319 (60%), Gaps = 21/319 (6%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+DDFD +K +G GSFG+VM V+ + + YA+K + K +V +V HTL E+ +L +D
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAID 108
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
PF+V + FSF+ + LY+VL FI+GGE+F HL+R GRF SRFY A+++ A E LH
Sbjct: 109 FPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHS 168
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
D+IYRDLKPEN+L+D G++ + DFG K + + +T T CGTPEYLAPE++L +GY
Sbjct: 169 LDLIYRDLKPENLLIDSTGYLKITDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYN 225
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
K VDWW LGVL+YEM G PP++ + ++Y+KI+ ++FP F + KDLL LL D
Sbjct: 226 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVD 285
Query: 619 PKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPP--------------YKPPVMGAM 662
+R G +G +IK+H +F W + K PP P V G
Sbjct: 286 LTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPPSFSKGESNGRLFEALYPRVDGPA 345
Query: 663 DTSNFDQEFTREQPVDSVV 681
DT +F +E ++P + V+
Sbjct: 346 DTRHFVEEV--QEPTEFVI 362
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 269 bits (688), Expect = 1e-71
Identities = 136/334 (40%), Positives = 202/334 (59%), Gaps = 13/334 (3%)
Query: 337 NLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKV 396
N K+D+A ++ + + K ++ + ++DDF+ +K +G GSFG+V
Sbjct: 9 NKKVDAAETVKEF--------LEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRV 60
Query: 397 MQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLY 456
M V+ + T YA+K + K +V +V HTL E+ +L + PF+V L++ F+ + LY
Sbjct: 61 MIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLY 120
Query: 457 LVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQ 516
+VL ++ GGE+F HL++ GRF SRFY A+++ A E LH D+IYRDLKPEN+L+D Q
Sbjct: 121 MVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQ 180
Query: 517 GHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTG 576
G++ + DFG K + + +T T CGTPEYLAPE++L +GY K VDWW LGVL+YEM G
Sbjct: 181 GYLKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAG 237
Query: 577 LPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLG--YHGSDEIKSH 634
PP++ + ++Y+KI+ +RFP F D KDLL LL D +R G G ++IK+
Sbjct: 238 YPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQ 297
Query: 635 PFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
+F W + K P+ P G DTSNFD
Sbjct: 298 KWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFD 331
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 266 bits (680), Expect = 8e-71
Identities = 129/308 (41%), Positives = 190/308 (60%), Gaps = 6/308 (1%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
S H + DF+ L V+GKGSFGKV+ ++ T +++A+K ++K I+ +V T+ E+
Sbjct: 403 SNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEK 462
Query: 432 TVLARVDNP-FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
VLA + P F+V L FQ+ ++LY V+ F+NGG+L Y +Q+ G+F + FY AE+
Sbjct: 463 RVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIA 522
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
L LH IIYRDLK +N++L+ GHI + DFG+CK N+ T TFCGTP+Y+APE
Sbjct: 523 VGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPE 582
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
++L Q Y K VDWW GVLL+EML G PP+ ED +++ I + + +P K+A L
Sbjct: 583 IILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSL 642
Query: 611 LIGLLCRDPKRRLGYHGSDE-----IKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTS 665
LL ++P +RLG G DE IK HPFF ++ W +++ + PP+KP + T
Sbjct: 643 CKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTE 702
Query: 666 NFDQEFTR 673
NFD F +
Sbjct: 703 NFDHSFLK 710
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 264 bits (674), Expect = 4e-70
Identities = 132/335 (39%), Positives = 208/335 (61%), Gaps = 6/335 (1%)
Query: 370 KPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA 429
+ + + +S+D+F LLKV+GKG+FGKV+ + ++T+++ A+K ++K I+ ++ A
Sbjct: 812 RAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARA 871
Query: 430 ERTVL---ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYT 486
E+ V + +PF+ L SFQ+ ++Y + FI GG+L +H+Q + R + R++FY
Sbjct: 872 EKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYA 930
Query: 487 AELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEY 546
AE+L AL+ HD +IYRDLK ENILL +GHI + D+GLCK M +T+TFCGTPE+
Sbjct: 931 AEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEF 990
Query: 547 LAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKD 606
+APE+L Q YTK VDWW GVLLY+ML P+ +D +++ IL D +P D +
Sbjct: 991 MAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGE 1050
Query: 607 AKDLLIGLLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDT 664
+ GLL +DP++RLG +DE+ PFF +++ + PPY P + DT
Sbjct: 1051 IVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDT 1110
Query: 665 SNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYV 699
S F+QEFT P + + L+ S Q++F G++++
Sbjct: 1111 SYFEQEFTSAPPTLTPLPSVLTTSQQEEFRGFSFM 1145
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 264 bits (674), Expect = 4e-70
Identities = 131/293 (44%), Positives = 186/293 (62%), Gaps = 5/293 (1%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV 437
S D F+ L+ +G GSFG+VM VR ++T YA+K + K +V +V H L E+ +L +
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 438 DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
D PF+V L+FSF+ + LYLV+ ++ GGE+F LQR GRF + FY A+++ A++ LH
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLH 159
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGY 557
D+I+RDLKPEN+L+D QG++ + DFG K + + +T T CGTPEYLAPE++L +GY
Sbjct: 160 SLDLIHRDLKPENLLIDQQGYLQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGY 216
Query: 558 TKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
K VDWW LGVL+YEM G PP+Y + ++Y+KI+ +RFP D K LL LL
Sbjct: 217 NKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQV 276
Query: 618 DPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
D +R G +G +IK+H +F SW + K P+ P G D SNFD
Sbjct: 277 DLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFD 329
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 263 bits (673), Expect = 5e-70
Identities = 134/295 (45%), Positives = 191/295 (64%), Gaps = 6/295 (2%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV 437
++ DF +++ +G GSFG+V VR + YA+K ++K +V +V HT ER +L V
Sbjct: 66 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLV 125
Query: 438 DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
++PF++ + +FQ + +++V+ +I GGELF L++ RF ++FY AE++ ALE LH
Sbjct: 126 EHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLH 185
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGY 557
+IIYRDLKPENILLD GHI + DFG K + Q T T CGTP+Y+APE++ + Y
Sbjct: 186 AHNIIYRDLKPENILLDRNGHIKITDFGFAK---EVQTVTWTLCGTPDYIAPEVITTKPY 242
Query: 558 TKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
K VDWW+LGVL+YEML G P+YD K Y+KILQ + +P F D DLL L+
Sbjct: 243 NKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITA 302
Query: 618 DPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV-MGAMDTSNFDQ 669
D RR+G GS +IK+HP+F+++ W+RL K PY+PP+ G DTS FDQ
Sbjct: 303 DLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQ 357
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 263 bits (672), Expect = 7e-70
Identities = 136/335 (40%), Positives = 202/335 (59%), Gaps = 10/335 (2%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
L I DF L V+GKGSFGKVM +R ++++YA+K ++K IV +V TL E+ VLA
Sbjct: 346 LHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLAL 405
Query: 437 VDNP------FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
F+ L +FQ+ ++LY V+ ++ GG+L YH+Q+ G+F + FY AE+
Sbjct: 406 GGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIA 465
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
L LH+ IIYRDLK +N++LD +GHI + DFG+CK N+ T TFCGTP+Y+APE
Sbjct: 466 IGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPE 525
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
++ Q Y K VDWW+ GVLLYEML G PP+ ED ++++ I++ + +P ++A +
Sbjct: 526 IIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAI 585
Query: 611 LIGLLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
G L + P +RLG G I++H FF + W+RL+ PP++P G NFD
Sbjct: 586 CKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCG-RSGENFD 644
Query: 669 QEFTREQPVDSVVNDFLSESVQQ-QFGGWTYVGSE 702
+ FTR P + + + S+ Q F G+TYV +
Sbjct: 645 KFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPD 679
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 263 bits (671), Expect = 9e-70
Identities = 136/336 (40%), Positives = 202/336 (59%), Gaps = 14/336 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
L + DFDL++VIG+GS+ KV+ VR + ++IYA+K ++K + ++ E+ V +
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQ 306
Query: 437 VD-NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
NPF+V L FQ++ +L+LV+ ++NGG+L +H+QR+ + +RFY AE+ AL
Sbjct: 307 ASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNF 366
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
LH+ IIYRDLK +N+LLD GHI L D+G+CK + + T+TFCGTP Y+APE+L G+
Sbjct: 367 LHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGE 426
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPY-YDEDVPKM------YKKILQDPLRFPDDFDKDAK 608
Y VDWW LGVL++EM+ G P+ D P M ++ IL+ P+R P A
Sbjct: 427 EYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKAS 486
Query: 609 DLLIGLLCRDPKRRLGYH---GSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTS 665
+L G L +DPK RLG G +IKSH FF + W L+ K +PP++P +
Sbjct: 487 HVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLD 546
Query: 666 NFDQEFTREQPVDSVVN--DFLSESVQQQFGGWTYV 699
NFD +FT E PV + D + Q +F G+ Y+
Sbjct: 547 NFDTQFTSE-PVQLTPDDEDAIKRIDQSEFEGFEYI 581
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 263 bits (671), Expect = 9e-70
Identities = 136/336 (40%), Positives = 202/336 (59%), Gaps = 14/336 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
L + DFDL++VIG+GS+ KV+ VR + ++IYA+K ++K + ++ E+ V +
Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQ 306
Query: 437 VD-NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
NPF+V L FQ++ +L+LV+ ++NGG+L +H+QR+ + +RFY AE+ AL
Sbjct: 307 ASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNF 366
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
LH+ IIYRDLK +N+LLD GHI L D+G+CK + + T+TFCGTP Y+APE+L G+
Sbjct: 367 LHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGE 426
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPY-YDEDVPKM------YKKILQDPLRFPDDFDKDAK 608
Y VDWW LGVL++EM+ G P+ D P M ++ IL+ P+R P A
Sbjct: 427 EYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKAS 486
Query: 609 DLLIGLLCRDPKRRLGYH---GSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTS 665
+L G L +DPK RLG G +IKSH FF + W L+ K +PP++P +
Sbjct: 487 HVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLD 546
Query: 666 NFDQEFTREQPVDSVVN--DFLSESVQQQFGGWTYV 699
NFD +FT E PV + D + Q +F G+ Y+
Sbjct: 547 NFDTQFTSE-PVQLTPDDEDAIKRIDQSEFEGFEYI 581
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 262 bits (670), Expect = 1e-69
Identities = 147/342 (42%), Positives = 207/342 (59%), Gaps = 9/342 (2%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
H+ F+LLKV+G+GSFGKV V+K D ++YA+K ++K+ + + V T E
Sbjct: 60 HEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRV-RTKME 118
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
R +L V++PFIV L ++FQ+ KLYL+L F+ GG+LF L +E F +FY AEL
Sbjct: 119 RDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELA 178
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
AL+ LH IIYRDLKPENILLD +GHI L DFGL K ++ ++K +FCGT EY+APE
Sbjct: 179 LALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPE 238
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
++ +G+T+ DWW+ GVL++EMLTG P+ +D + IL+ L P +A+ L
Sbjct: 239 VVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSL 298
Query: 611 LIGLLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
L L R+P RLG G +EIK H FF+ + W +L + PP+KP DT FD
Sbjct: 299 LRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFD 358
Query: 669 QEFTREQPVDSVVNDFLSESVQQQFGGWTYVG--SEQLGQSM 708
EFT + P DS S + Q F G+++V S+ Q+M
Sbjct: 359 PEFTAKTPKDS-PGIPPSANAHQLFRGFSFVAITSDDESQAM 399
Score = 108 bits (269), Expect = 4e-23
Identities = 81/255 (31%), Positives = 126/255 (48%), Gaps = 17/255 (6%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
D +++ + IG GS+ + + TN +A+K I KS K + T + +L +
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS----KRDPTEEI--EILLRYGQH 473
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
P I+ LK + + +Y+V + GGEL + R+ F + + +E LH
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 500 DIIYRDLKPENIL-LDYQGH---IALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
+++RDLKP NIL +D G+ I +CDFG K + T C T ++APE+L Q
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYD--EDVP-KMYKKILQDPLRFPDDF----DKDAK 608
GY D W+LGVLLY MLTG P+ + +D P ++ +I + AK
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAK 653
Query: 609 DLLIGLLCRDPKRRL 623
DL+ +L DP +RL
Sbjct: 654 DLVSKMLHVDPHQRL 668
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 262 bits (669), Expect = 2e-69
Identities = 149/454 (32%), Positives = 241/454 (52%), Gaps = 33/454 (7%)
Query: 268 PIFNKISTFDVTRRLPFLKIDVFARIPSILLPSQNWQETQISNNDILGDY---VKKIRNN 324
P+FN+ TF++ + R +L+ +W T S ND +G + +++++
Sbjct: 256 PVFNETFTFELQPQ---------DRDKRLLIEVWDWDRT--SRNDFMGSFSFSLEELQKE 304
Query: 325 ---------SDIHLDSFHLPLNLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPSTHK 375
S + + +++P + + +R H K N + + S
Sbjct: 305 PVDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDEVRHDRRPNEKRRMDNKDMPHNMSKRD 364
Query: 376 HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA 435
+ DF+ +KVIGKGSFGKV+ +R T+++YA+K +RK I+ ++ + E+ +LA
Sbjct: 365 MIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILA 424
Query: 436 RVDNP-FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
P F+V + FQ+ ++L+ V+ + GG+L YH+Q+ GRF S + FY E+ AL
Sbjct: 425 LSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALF 484
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
LH+ DIIYRDLK +NILLD +GH+ L DFGL K + +++ T TFCGTP Y+APE++
Sbjct: 485 FLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSY 544
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGL 614
Y+ DWW+ GVLL+E + G P+ +D +++ I FP F +A D++
Sbjct: 545 DPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSF 604
Query: 615 LCRDPKRRL--GYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFT 672
L + P RL G + EI +HPFF + W + + PP KP + D SNFD FT
Sbjct: 605 LTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFT 664
Query: 673 REQ----PVDSVVNDFLSESVQQQFGGWTYVGSE 702
+E+ P D + F+ Q F G++++ E
Sbjct: 665 KEKTDLTPTDKL---FMMNLDQNDFIGFSFMNPE 695
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 261 bits (668), Expect = 2e-69
Identities = 150/363 (41%), Positives = 213/363 (58%), Gaps = 8/363 (2%)
Query: 354 IELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRK---RDTNKIYAL 410
+E E + ++++S K K F+LLKV+G+GS+GKV VRK D ++YA+
Sbjct: 32 LEEEGVVKEIDISHHVKEGFEK-ADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAM 90
Query: 411 KAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYH 470
K ++K+ + + V + ER +LA V++PFIV L ++FQ+ KLYL+L F+ GG+LF
Sbjct: 91 KVLKKATLKVRDRVRSKM-ERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 149
Query: 471 LQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLN 530
L +E F +FY AEL AL+ LH IIYRDLKPENILLD +GHI + DFGL K
Sbjct: 150 LSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEA 209
Query: 531 MKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYK 590
+ ++ +FCGT EY+APE++ +G+T+ DWW+ GVL++EMLTG P+ +D +
Sbjct: 210 IDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMA 269
Query: 591 KILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRL--GYHGSDEIKSHPFFNQLSWKRLKMK 648
IL+ L P +A+ LL L R+P RL G G +EIK HPFF + W L K
Sbjct: 270 LILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRK 329
Query: 649 GYIPPYKPPVMGAMDTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYVGSEQLGQSM 708
PP+KP V DT +FD EFT P DS S + F G+++V S + +
Sbjct: 330 EIKPPFKPAVGRPEDTFHFDPEFTARTPTDS-PGVPPSANAHHLFRGFSFVASSLIQEPS 388
Query: 709 LPD 711
D
Sbjct: 389 QQD 391
Score = 107 bits (266), Expect = 8e-23
Identities = 91/316 (28%), Positives = 143/316 (44%), Gaps = 38/316 (12%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
D +++ + IG GS+ + + T+ YA+K I KS E+ +L +
Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEI------EILLRYGQH 466
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
P I+ LK + + +YLV+ + GGEL + R+ F + + ++ LH
Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526
Query: 500 DIIYRDLKPENILL-DYQGH---IALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
+++RDLKP NIL D G I +CDFG K T C T ++APE+L Q
Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQ 586
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYD--EDVP-KMYKKILQDPLRFP----DDFDKDAK 608
GY D W+LG+LLY ML G P+ + +D P ++ +I D AK
Sbjct: 587 GYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAK 646
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFF--------NQLSWKRLKMKGYIPPYKPPVMG 660
D++ +L DP +RL + ++ HP+ NQLS + + + V G
Sbjct: 647 DVVSKMLHVDPHQRL---TAMQVLKHPWVVNREYLSPNQLSRQDVHL----------VKG 693
Query: 661 AMDTSNFDQEFTREQP 676
AM + F T + P
Sbjct: 694 AMAATYFALNRTPQAP 709
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 261 bits (668), Expect = 2e-69
Identities = 128/303 (42%), Positives = 191/303 (62%), Gaps = 7/303 (2%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKR---DTNKIYALKAIRKSYIV-SKSEVTHTLAERTVLAR 436
DF+ LK++G+G +GKV QVRK+ D IYA+K I K + ++ ++ H ER +L
Sbjct: 22 DFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILET 81
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+++PF+ L ++FQ++EKLYLVL F++GGEL+ L+R+ + +RFY +E++ A+E L
Sbjct: 82 INSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEHL 141
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H DI+YRDLKP+N++L+ GH+ L DFGLCK +K EKT TFCGT EY+APE++ G
Sbjct: 142 HGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFCGTHEYMAPEMIRKVG 201
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLC 616
+ VD W LG+L+Y+M G PP+ E K IL+ +R P KDL+ ++
Sbjct: 202 HDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSASGKDLIKRIIK 261
Query: 617 RDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQP 676
RDP R+ +IK H FF ++ W +L + PP+KP + D S+FD+ FT P
Sbjct: 262 RDPTLRITI---PDIKEHEFFEEIDWDKLMAHDFEPPFKPTLANLEDVSHFDESFTSIAP 318
Query: 677 VDS 679
+S
Sbjct: 319 EES 321
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 261 bits (668), Expect = 2e-69
Identities = 132/313 (42%), Positives = 195/313 (62%), Gaps = 4/313 (1%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
K ++ F+LLKV+GKGSFGKVM V + N+ YA+K ++K I+ + T ER VL
Sbjct: 231 KKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVL 290
Query: 435 ARVDN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
PF+ L SFQ++E L+ V+ ++NGG+L +H+Q+ +FD +R+RFY E++ AL
Sbjct: 291 ILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVAL 350
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM-KDQEKTTTFCGTPEYLAPELL 552
+ LH +IIYRDLK +N+LLD GHI L DFG+ K M ++ +TFCGTP+Y++PE++
Sbjct: 351 QFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEII 410
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
GQ Y + VD+W+ GVL+YEML G P++ E +++ IL + FP K+A L
Sbjct: 411 KGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLS 470
Query: 613 GLLCRDPKRRLGYHGSDE--IKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQE 670
L R+P RLG + I+ H FF + WKR + + PP+KP + D SNFD +
Sbjct: 471 ALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDD 530
Query: 671 FTREQPVDSVVND 683
FT E+ + V+D
Sbjct: 531 FTNEKAALTPVHD 543
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 261 bits (668), Expect = 2e-69
Identities = 132/313 (42%), Positives = 195/313 (62%), Gaps = 4/313 (1%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
K ++ F+LLKV+GKGSFGKVM V + N+ YA+K ++K I+ + T ER VL
Sbjct: 368 KKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVL 427
Query: 435 ARVDN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
PF+ L SFQ++E L+ V+ ++NGG+L +H+Q+ +FD +R+RFY E++ AL
Sbjct: 428 ILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVAL 487
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM-KDQEKTTTFCGTPEYLAPELL 552
+ LH +IIYRDLK +N+LLD GHI L DFG+ K M ++ +TFCGTP+Y++PE++
Sbjct: 488 QFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEII 547
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
GQ Y + VD+W+ GVL+YEML G P++ E +++ IL + FP K+A L
Sbjct: 548 KGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLS 607
Query: 613 GLLCRDPKRRLGYHGSDE--IKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQE 670
L R+P RLG + I+ H FF + WKR + + PP+KP + D SNFD +
Sbjct: 608 ALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDD 667
Query: 671 FTREQPVDSVVND 683
FT E+ + V+D
Sbjct: 668 FTNEKAALTPVHD 680
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 261 bits (667), Expect = 3e-69
Identities = 140/316 (44%), Positives = 207/316 (65%), Gaps = 13/316 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVT-HTLAERT 432
+S+++F+LLKV+G G++GKV VRK D K+YA+K +RK+ +V +++ HT ER+
Sbjct: 28 VSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERS 87
Query: 433 VLARVDN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
VL V PF+V L ++FQ+ KL+L+L +++GGE+F HL + F + R Y E++
Sbjct: 88 VLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVL 147
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK-LNMKDQEKTTTFCGTPEYLAPE 550
ALE LH IIYRDLK EN+LLD +GHI L DFGL K +++E+T +FCGT EY+APE
Sbjct: 148 ALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPE 207
Query: 551 LLLGQ-GYTKVVDWWTLGVLLYEMLTGLPPYYDE----DVPKMYKKILQDPLRFPDDFDK 605
++ + G+ K VDWW+LG+LL+E+LTG P+ E ++ ++IL+ FP
Sbjct: 208 IIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGP 267
Query: 606 DAKDLLIGLLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMD 663
A+DLL LLC+DPK+RLG G+ E+++HPFF L W L + P++P + +D
Sbjct: 268 VAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELD 327
Query: 664 TSNFDQEFTREQPVDS 679
NF +EFTR +PV S
Sbjct: 328 VGNFAEEFTRLEPVYS 343
Score = 105 bits (261), Expect = 3e-22
Identities = 84/259 (32%), Positives = 128/259 (48%), Gaps = 27/259 (10%)
Query: 388 IGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN-PFIVPLK 446
+G+GSF + R+R + + +A+K I+S+ +T E L + P +V L
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVK------ILSRRLEANTQREVAALRLCQSHPNVVNLH 470
Query: 447 FSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD-FDIIYRD 505
YLVL + GGEL H++++ F S + L+ A+ +H+ +++RD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 506 LKPENILL--DYQGH-IALCDFGLCKLNMKDQE-KTTTFCGTPEYLAPELLLGQGYTKVV 561
LKPENIL D G + + DFG +L + T C T +Y APELL QGY +
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 590
Query: 562 DWWTLGVLLYEMLTGLPPYY-------DEDVPKMYKKILQDPLRFPDD------FDKDAK 608
D W+LGV+LY ML+G P+ ++ KI + RF D ++AK
Sbjct: 591 DLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREG--RFSLDGEAWQGVSEEAK 648
Query: 609 DLLIGLLCRDPKRRLGYHG 627
+L+ GLL DP +RL G
Sbjct: 649 ELVRGLLTVDPAKRLKLEG 667
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 260 bits (665), Expect = 4e-69
Identities = 141/323 (43%), Positives = 200/323 (61%), Gaps = 5/323 (1%)
Query: 382 FDLLKVIGKGSFGKVMQVRKR---DTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
F+LLKV+G+GSFGKV VRK+ D ++YA+K ++K+ + + V T ER +L V+
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRV-RTKMERDILVEVN 131
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+PFIV L ++FQ+ KLYL+L F+ GG++F L +E F +FY AEL AL+ LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I+YRDLKPENILLD GHI L DFGL K ++ ++K +FCGT EY+APE++ +G++
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
+ DWW+ GVL++EMLTG P+ +D + IL+ L P +A+ LL L R+
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 619 PKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVD 678
P RLG G +EIK H FF + W +L + PP+KP DT FD EFT + P D
Sbjct: 312 PANRLGSEGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKD 371
Query: 679 SVVNDFLSESVQQQFGGWTYVGS 701
S S + Q F G+++V +
Sbjct: 372 SPGLP-ASANAHQLFKGFSFVAT 393
Score = 100 bits (250), Expect = 6e-21
Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 22/265 (8%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV-DNP 440
++L + IG GS+ + TN +A+K I KS E+ +L R +P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIE-------ILMRYGQHP 478
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
I+ LK F +YLV + GGEL + ++ F + + ++ LH
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538
Query: 501 IIYRDLKPENILLDYQG----HIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
+++RDLKP NIL + I +CDFG K + T C T ++APE+L+ QG
Sbjct: 539 VVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQG 598
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYD--EDVP-KMYKKILQDPLRFP----DDFDKDAKD 609
Y D W+LGVL Y ML G P+ + D P ++ +I D+ AKD
Sbjct: 599 YDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKD 658
Query: 610 LLIGLLCRDPKRRLGYHGSDEIKSH 634
LL +L DP +R + +++I H
Sbjct: 659 LLSHMLHMDPHQR---YTAEQILKH 680
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 259 bits (661), Expect = 1e-68
Identities = 143/325 (44%), Positives = 199/325 (61%), Gaps = 7/325 (2%)
Query: 382 FDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
F+LLKV+G+GSFGKV VRK D+ +YA+K ++K+ + + V T ER +LA V+
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRV-RTKMERDILADVN 120
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+PF+V L ++FQ+ KLYL+L F+ GG+LF L +E F +FY AEL L+ LH
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
IIYRDLKPENILLD +GHI L DFGL K + ++K +FCGT EY+APE++ QG++
Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS 240
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
DWW+ GVL++EMLTG P+ +D + IL+ L P +A+ LL L R+
Sbjct: 241 HSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRN 300
Query: 619 PKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQP 676
P RLG G++EIK H F++ + W +L + PP+KP V DT FD EFT P
Sbjct: 301 PANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTP 360
Query: 677 VDSVVNDFLSESVQQQFGGWTYVGS 701
DS S Q F G+++V +
Sbjct: 361 KDS-PGIPPSAGAHQLFRGFSFVAT 384
Score = 113 bits (282), Expect = 1e-24
Identities = 83/271 (30%), Positives = 132/271 (48%), Gaps = 20/271 (7%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
D + + + IG GS+ + + + TN YA+K I KS E+ +L +
Sbjct: 416 DGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEI------EILLRYGQH 469
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
P I+ LK + + +YLV + GGEL + R+ F + F + +E LH
Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529
Query: 500 DIIYRDLKPENIL-LDYQGH---IALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
+++RDLKP NIL +D G+ + +CDFG K + T C T ++APE+L Q
Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 589
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYD--EDVP-KMYKKILQDPLRFP----DDFDKDAK 608
GY + D W+LG+LLY ML G P+ + D P ++ +I + + AK
Sbjct: 590 GYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAK 649
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQ 639
DL+ +L DP +RL + ++ HP+ Q
Sbjct: 650 DLVSKMLHVDPHQRL---TAKQVLQHPWVTQ 677
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 256 bits (654), Expect = 8e-68
Identities = 132/339 (38%), Positives = 203/339 (58%), Gaps = 8/339 (2%)
Query: 368 DYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHT 427
D + ++ DF V+G+G FGKV+ ++TN+++A+KA++K IV++ EV
Sbjct: 643 DRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSL 702
Query: 428 LAERTVLARVDN---PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRF 484
+ E+ + V++ PF+V L FQ+ E + V+ + GG+L H+ + F R+ F
Sbjct: 703 MCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV-FSEPRAVF 761
Query: 485 YTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTP 544
Y A ++ L+ LH+ I+YRDLK +N+LLD +G + + DFGLCK M ++T+TFCGTP
Sbjct: 762 YAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTP 821
Query: 545 EYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFD 604
E+LAPE+L YT+ VDWW LGVL+YEML G P+ +D +++ I+ D +R+P
Sbjct: 822 EFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLS 881
Query: 605 KDAKDLLIGLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
+A ++ LL R+P+RRLG D ++K HPFF + W L K PP+ P + G
Sbjct: 882 TEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGRE 941
Query: 663 DTSNFDQEFTREQPVDSVVND--FLSESVQQQFGGWTYV 699
D SNFD EFT E P+ + + LSE Q+ F + Y+
Sbjct: 942 DVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYI 980
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 256 bits (653), Expect = 1e-67
Identities = 143/340 (42%), Positives = 208/340 (61%), Gaps = 7/340 (2%)
Query: 382 FDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
F+LLKV+G+GSFGKV VRK RD+ +YA+K ++K+ + + T ER +LA +
Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR-QRTKLERNILAHIS 162
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+PFIV L ++FQ+ KLYL+L F+ GG+LF L +E F +FY AEL ALE LH
Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 222
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I+YRDLKPENILLD GHI + DFGL K + ++KT +FCGT EY+APE++ +G++
Sbjct: 223 LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 282
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
D+W+LGVL++EMLTG P+ D +IL+ L P ++A+ LL L R+
Sbjct: 283 MAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRN 342
Query: 619 PKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQP 676
+ RLG G +EIK H FF ++ + +L K PP+KP + TS FD EFT+ P
Sbjct: 343 SQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTP 402
Query: 677 VDSVVNDFLSESVQQQFGGWTYVGSEQLGQSMLPDRSFQT 716
DS S + + F G+++V + + + L +S ++
Sbjct: 403 KDSPALP-ASANGHEIFRGFSFVSNAVMEERKLIAKSVRS 441
Score = 107 bits (268), Expect = 5e-23
Identities = 79/270 (29%), Positives = 129/270 (47%), Gaps = 18/270 (6%)
Query: 366 SVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVT 425
SV P+ + DD+++L+ IG G+ V + + + T + YA+K ++K+ + EV
Sbjct: 438 SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD 497
Query: 426 HTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRS-RF 484
+L + F+V L ++ +Y++ GGEL L + +
Sbjct: 498 ------ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAA 551
Query: 485 YTAELLCALEALHDFDIIYRDLKPENILLDYQ----GHIALCDFGLCKLNMKDQEKTTTF 540
A LL A++ LH + +RDL NIL + + + DFG K + + T
Sbjct: 552 IMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTP 611
Query: 541 CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYY--DEDVPKMYKKILQD--- 595
C T +++APE+L QGY + D W+LGVLL+ MLTG P+ D P + + D
Sbjct: 612 CYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKI 671
Query: 596 PLRFP--DDFDKDAKDLLIGLLCRDPKRRL 623
+ P D +AKDL+ +L DP RR+
Sbjct: 672 SMTHPVWDTISDEAKDLVRKMLDVDPNRRV 701
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 256 bits (653), Expect = 1e-67
Identities = 143/340 (42%), Positives = 208/340 (61%), Gaps = 7/340 (2%)
Query: 382 FDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
F+LLKV+G+GSFGKV VRK RD+ +YA+K ++K+ + + T ER +LA +
Sbjct: 47 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR-QRTKLERNILAHIS 105
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+PFIV L ++FQ+ KLYL+L F+ GG+LF L +E F +FY AEL ALE LH
Sbjct: 106 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 165
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I+YRDLKPENILLD GHI + DFGL K + ++KT +FCGT EY+APE++ +G++
Sbjct: 166 LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 225
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
D+W+LGVL++EMLTG P+ D +IL+ L P ++A+ LL L R+
Sbjct: 226 MAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRN 285
Query: 619 PKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQP 676
+ RLG G +EIK H FF ++ + +L K PP+KP + TS FD EFT+ P
Sbjct: 286 SQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTP 345
Query: 677 VDSVVNDFLSESVQQQFGGWTYVGSEQLGQSMLPDRSFQT 716
DS S + + F G+++V + + + L +S ++
Sbjct: 346 KDSPALP-ASANGHEIFRGFSFVSNAVMEERKLIAKSVRS 384
Score = 107 bits (268), Expect = 5e-23
Identities = 79/270 (29%), Positives = 129/270 (47%), Gaps = 18/270 (6%)
Query: 366 SVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVT 425
SV P+ + DD+++L+ IG G+ V + + + T + YA+K ++K+ + EV
Sbjct: 381 SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD 440
Query: 426 HTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRS-RF 484
+L + F+V L ++ +Y++ GGEL L + +
Sbjct: 441 ------ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAA 494
Query: 485 YTAELLCALEALHDFDIIYRDLKPENILLDYQ----GHIALCDFGLCKLNMKDQEKTTTF 540
A LL A++ LH + +RDL NIL + + + DFG K + + T
Sbjct: 495 IMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTP 554
Query: 541 CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYY--DEDVPKMYKKILQD--- 595
C T +++APE+L QGY + D W+LGVLL+ MLTG P+ D P + + D
Sbjct: 555 CYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKI 614
Query: 596 PLRFP--DDFDKDAKDLLIGLLCRDPKRRL 623
+ P D +AKDL+ +L DP RR+
Sbjct: 615 SMTHPVWDTISDEAKDLVRKMLDVDPNRRV 644
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 255 bits (652), Expect = 1e-67
Identities = 139/335 (41%), Positives = 214/335 (63%), Gaps = 14/335 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSE-VTHTLAERT 432
+S+++F LL+V+GKG++GKV VRK +D N IYA+K +RK+ +++K + + HT+AER
Sbjct: 12 VSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAERQ 71
Query: 433 VLARV-DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
VL R+ PF+V L ++FQ+ KL++V+ ++ GGELF HL G FDL +RF AEL+
Sbjct: 72 VLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELVV 131
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQ-EKTTTFCGTPEYLAPE 550
A+++LH +IYRDLK ENILLD +GH+ L DFGL KL + + ++ ++CGT EY++PE
Sbjct: 132 AIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMSPE 191
Query: 551 LLLGQ--GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPK----MYKKILQDPLRFPDDFD 604
++ GY+ VVDWW+LGV+ +E+LTG P+ + + K+I+ + FP D
Sbjct: 192 VINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTMD 251
Query: 605 KDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDT 664
DA+D + LL + ++RLGY+G DEIK+H F + + W + P P + +DT
Sbjct: 252 VDARDFIGQLLEKKLEKRLGYNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRIGHDLDT 311
Query: 665 SNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYV 699
F EFT + P+ S L+ + F G++YV
Sbjct: 312 QFFSAEFTSQPPLYSPAESPLNANT--LFRGYSYV 344
Score = 105 bits (263), Expect = 2e-22
Identities = 86/275 (31%), Positives = 133/275 (48%), Gaps = 44/275 (16%)
Query: 387 VIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD-NPFIVPL 445
++GKG+F V + + +A+K IVS+ + E +L V +P IV L
Sbjct: 387 LLGKGAFSVVRRCERVVDGAQFAVK------IVSQKFASQAQREARILEMVQGHPNIVQL 440
Query: 446 KFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRD 505
YLV+ + G EL +++ RF S + +L+ A++ LHD I++RD
Sbjct: 441 HDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVHRD 500
Query: 506 LKPENIL---LDYQGHIALCDFGLCKL---NMKDQEKTT-------------------TF 540
LKPENIL +D + L DFG +L +M+ Q K+ T
Sbjct: 501 LKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHNHSLHSETP 560
Query: 541 CGTPEYLAPELL-LGQG---YTKVVDWWTLGVLLYEMLTGLPPYY----DEDVPKMYKKI 592
C T +Y APE+L +G Y + D W+LGV+L+ ML+G P++ E ++ ++I
Sbjct: 561 CFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRI 620
Query: 593 LQDPLRFPDD----FDKDAKDLLIGLLCRDPKRRL 623
+ F D DAK+L+ GLL DPK+RL
Sbjct: 621 CRAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRL 655
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 254 bits (649), Expect = 3e-67
Identities = 122/293 (41%), Positives = 187/293 (63%), Gaps = 5/293 (1%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV 437
S+ DFD L +G G+FG+V V+++ +ALK + ++ + H E++VL V
Sbjct: 45 SLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEV 104
Query: 438 DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
+PF++ L +++ LY+++ ++ GGELF +L+ GRF + FY+AE++CA+E LH
Sbjct: 105 SHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLH 164
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGY 557
+I+YRDLKPENILLD GHI L DFG K K ++T T CGTPEYLAPE++ +G+
Sbjct: 165 SKEIVYRDLKPENILLDRDGHIKLTDFGFAK---KLVDRTWTLCGTPEYLAPEVIQSKGH 221
Query: 558 TKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
+ VDWW LG+L++EML+G PP++D++ +Y+KIL + FP D KDL+ LL
Sbjct: 222 GRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVV 281
Query: 618 DPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
D RRLG +G++++K H +F + W+ + + PP P + G DTSNF+
Sbjct: 282 DRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFE 334
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 253 bits (646), Expect = 7e-67
Identities = 130/318 (40%), Positives = 198/318 (61%), Gaps = 6/318 (1%)
Query: 371 PSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
P L+++DF L V+G+G FGKV+ R + +++A+KA++K IV++ EV + E
Sbjct: 604 PLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCE 663
Query: 431 RTVLARVDN---PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTA 487
+ +LA V + PF+V L FQ+ E + V+ + GG+L H+ + F R+ FY+A
Sbjct: 664 KRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDV-FSEPRAIFYSA 722
Query: 488 ELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYL 547
++ L+ LH+ I+YRDLK +N+LLD +G++ + DFGLCK M ++T+TFCGTPE+L
Sbjct: 723 CVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFL 782
Query: 548 APELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDA 607
APE+L YT+ VDWW LGVLLYEML G P+ +D +++ I+ D +R+P +A
Sbjct: 783 APEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEA 842
Query: 608 KDLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTS 665
++ LL R+P+RRLG ++++K PFF L W+ L + PP+ P + G D S
Sbjct: 843 IGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVS 902
Query: 666 NFDQEFTREQPVDSVVND 683
NFD+EFT E P S D
Sbjct: 903 NFDEEFTGEAPTLSPPRD 920
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 253 bits (646), Expect = 7e-67
Identities = 130/318 (40%), Positives = 198/318 (61%), Gaps = 6/318 (1%)
Query: 371 PSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
P L+++DF L V+G+G FGKV+ R + +++A+KA++K IV++ EV + E
Sbjct: 604 PLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCE 663
Query: 431 RTVLARVDN---PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTA 487
+ +LA V + PF+V L FQ+ E + V+ + GG+L H+ + F R+ FY+A
Sbjct: 664 KRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDV-FSEPRAIFYSA 722
Query: 488 ELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYL 547
++ L+ LH+ I+YRDLK +N+LLD +G++ + DFGLCK M ++T+TFCGTPE+L
Sbjct: 723 CVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFL 782
Query: 548 APELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDA 607
APE+L YT+ VDWW LGVLLYEML G P+ +D +++ I+ D +R+P +A
Sbjct: 783 APEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEA 842
Query: 608 KDLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTS 665
++ LL R+P+RRLG ++++K PFF L W+ L + PP+ P + G D S
Sbjct: 843 IGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVS 902
Query: 666 NFDQEFTREQPVDSVVND 683
NFD+EFT E P S D
Sbjct: 903 NFDEEFTGEAPTLSPPRD 920
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 253 bits (646), Expect = 7e-67
Identities = 134/346 (38%), Positives = 200/346 (57%), Gaps = 16/346 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+S++DF LL VIG+GS+ KV+Q T +IYA+K I+K ++ E++V
Sbjct: 248 VSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEA 307
Query: 437 VDN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
N PF+V L FQ+ +L+ V+ F+ GG+L +H+Q++ + +RFY+ E++ AL
Sbjct: 308 ASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHF 367
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
LH IIYRDLK +N+L+D +GHI L D+G+CK N+KD + T+TFCGTP Y+APE+L G
Sbjct: 368 LHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGD 427
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPY--------YDEDVPKMYKKILQDPLRFPDDFDKDA 607
Y VDWW LGVL++EM+ G P+ + +++ IL+ +R P A
Sbjct: 428 EYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRA 487
Query: 608 KDLLIGLLCRDPKRRLG-----YHGSDEIKSHPFFNQ-LSWKRLKMKGYIPPYKPPVMGA 661
+L G L +DP RLG G ++K H FF + W+ L+ K PPY P V
Sbjct: 488 SGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESD 547
Query: 662 MDTSNFDQEFTREQPVDSVVN-DFLSESVQQQFGGWTYVGSEQLGQ 706
D ++FD +FT E P S N D ++ Q +F G+ YV Q+ +
Sbjct: 548 RDLTHFDHQFTDELPQLSPDNPDVIARIDQSEFDGFEYVNPLQMSR 593
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 252 bits (643), Expect = 2e-66
Identities = 145/331 (43%), Positives = 200/331 (59%), Gaps = 9/331 (2%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRK---RDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
H F+LL+V+G+GSFGKV VRK +D +YA+K ++K+ + K V T E
Sbjct: 191 HDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRST-NE 249
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
R +LA V + FIV L ++FQ+ KLYL+L F+ GG+LF L +E F +FY AEL
Sbjct: 250 RKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELA 309
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
A+ LH IIYRDLKPENILLD GHIAL DFGL K + D KT +FCGT EY+APE
Sbjct: 310 LAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPL-DGSKTYSFCGTVEYMAPE 368
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
++ +G+ DWW+ GVL+YEMLTG P++ + + +IL+ L P++ +A+ L
Sbjct: 369 IVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSPEAQSL 428
Query: 611 LIGLLCRDPKRRL--GYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
L L R+P+ RL G G +IK+H FF + W RL+ K PP+ P V D FD
Sbjct: 429 LRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAV-SRDDAFYFD 487
Query: 669 QEFTREQPVDSVVNDFLSESVQQQFGGWTYV 699
E+T + P DS +S S + F G+++V
Sbjct: 488 VEYTSKSPRDSPGGP-ISASAHEIFRGFSFV 517
Score = 107 bits (267), Expect = 6e-23
Identities = 67/207 (32%), Positives = 104/207 (49%), Gaps = 7/207 (3%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHT--LAERTVLARVD 438
+++LL+ +G+G+F R + K YA+K I K+ + + S T E ++ R
Sbjct: 567 EYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYG 626
Query: 439 N-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
N P IV L ++ + YLV+ + GGEL + G+ S + + A+ LH
Sbjct: 627 NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLH 686
Query: 498 DFDIIYRDLKPENILLDYQGH----IALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLL 553
+ +++RDLKP N++ + LCD G K D T C T ++APE+L
Sbjct: 687 EHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLK 746
Query: 554 GQGYTKVVDWWTLGVLLYEMLTGLPPY 580
QGY D W+LGVLLY ML+G P+
Sbjct: 747 RQGYDLACDIWSLGVLLYIMLSGRTPF 773
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 244 bits (622), Expect = 4e-64
Identities = 126/300 (42%), Positives = 180/300 (60%), Gaps = 5/300 (1%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
+T I DF+ L+ +G GSFG+V V+ YA+K + K IV ++ HT ER
Sbjct: 191 TTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDER 250
Query: 432 TVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
+L+RV +PFI L +FQ ++ L++V+ F GGELF L++ RF ++FY AE++
Sbjct: 251 YILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVIL 310
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPEL 551
AL+ LH I+YRDLKPEN+LLD GH+ + DFG K T CGTP+YLAPE+
Sbjct: 311 ALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAK--RVSTSNCCTLCGTPDYLAPEI 368
Query: 552 LLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLL 611
+ + Y K DWW+LG+L++EML G PP+Y E+ K+Y+ IL+ + +P F + DLL
Sbjct: 369 ISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLL 428
Query: 612 IGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM-DTSNFD 668
LL RD R G GS +I HP+F +SW ++ + PY PP+ M D+S FD
Sbjct: 429 SHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFD 488
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 241 bits (614), Expect = 4e-63
Identities = 123/331 (37%), Positives = 205/331 (61%), Gaps = 10/331 (3%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL-- 434
L+++ F L+ V+G+G FGKV+ + T+ YALK ++K I+ + EV + E+ +
Sbjct: 685 LTVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEV 744
Query: 435 -ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
+R +PF+V L FQ++E ++ + + GG+L H+ + FD R FY A ++ L
Sbjct: 745 SSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIH-DDVFDEVRGCFYAACVVLGL 803
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLL 553
+ LH +IIYRD+K +N+LLD +G++ + DFGLCK NM +KT+TFCGTPE+LAPE+L
Sbjct: 804 DFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLS 863
Query: 554 GQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIG 613
YT+ +DWW LGVL++EML G PP+ +D +++ I+ + +R+P ++ ++
Sbjct: 864 DSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRR 923
Query: 614 LLCRDPKRRLGY--HGSDEIKSHPFFNQLSWK--RLKMKGYIPPYKPPVMGAMDTSNFDQ 669
LL + P++RLGY +++IK FF +SW+ +L + PP++P + D SNFD
Sbjct: 924 LLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDL 983
Query: 670 EFTREQPVDSVVNDF--LSESVQQQFGGWTY 698
EFT+E+ S + ++E+ Q+ F + +
Sbjct: 984 EFTQEKARFSAASSTRPITEADQRLFNNFDF 1014
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 238 bits (608), Expect = 2e-62
Identities = 134/373 (35%), Positives = 207/373 (54%), Gaps = 51/373 (13%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
L +DDF+ LKVIG+G+FG+V V+K+DT IYA+K +RKS ++ K +V H AER +L
Sbjct: 85 LGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDILVE 144
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
D ++V + +SFQ LYL++ F+ GG++ L ++ ++FY +E + A++A+
Sbjct: 145 ADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAI 204
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCK------------------------LNMK 532
H I+RD+KP+N+LLD +GH+ L DFGLC NM
Sbjct: 205 HQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMN 264
Query: 533 DQEKTTTF-----------CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYY 581
+ K T+ GTP+Y+APE+ + GY K+ DWW+LGV++YEML G PP+
Sbjct: 265 SKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFC 324
Query: 582 DEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFF 637
E + Y+K++ ++ L FP + + AKDL++ C D + R+G G +EIK HPFF
Sbjct: 325 SETPQETYRKVMNWKETLVFPPEVPISEKAKDLIL-RFCIDSENRIGNSGVEEIKGHPFF 383
Query: 638 NQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ--EFTREQPVDSVVN-DFLSES------ 688
+ W+ ++ + P + + DTSNFD E QPV + D+ S+
Sbjct: 384 EGVDWEHIRERPAAIPIE--IKSIDDTSNFDDFPESDILQPVPNTTEPDYKSKDWVFLNY 441
Query: 689 VQQQFGGWTYVGS 701
++F G T GS
Sbjct: 442 TYKRFEGLTQRGS 454
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 238 bits (608), Expect = 2e-62
Identities = 126/333 (37%), Positives = 194/333 (57%), Gaps = 32/333 (9%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+SIDDF+++K I +G+FGKV RKR T +A+K ++K ++ K+++ L ER +L
Sbjct: 665 ISIDDFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNILIT 724
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
V PF+V +SF + LYLV+ ++NGG+L+ LQ+ G D +R Y AEL+ ALE L
Sbjct: 725 VRYPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLALEYL 784
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM------------------------K 532
H I++RDLKP+N+L+ Y GHI L DFGL K+ + K
Sbjct: 785 HSLKIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGLINNTIDLSGHESDVSPRTNSHHFQK 844
Query: 533 DQEKTT---TFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMY 589
+QE+ + GTP+YLAPE+LLG + DWW+ G++L+E+LTG+PP+ K++
Sbjct: 845 NQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTGIPPFTASRPEKIF 904
Query: 590 KKILQDPLRFPD---DFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLK 646
IL + +PD + +A+DL+ LL +P++RLG +G+ E+KSHPFF + W+ L
Sbjct: 905 DNILNGKMPWPDVPGEMSYEAQDLINRLLVHEPEKRLGANGAAEVKSHPFFQGVDWENLA 964
Query: 647 MKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDS 679
++ + P DTS F F+ D+
Sbjct: 965 LQK--AAFVPQPESINDTSYFVSRFSESSCSDT 995
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 236 bits (603), Expect = 7e-62
Identities = 120/324 (37%), Positives = 190/324 (58%), Gaps = 30/324 (9%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+SIDDF+++K I +G+FG V+ RK T ++A+K +RK+ ++ K+ V LAER +L
Sbjct: 823 ISIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDILIN 882
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
NPF+V +SF SE LYLV+ ++NGG+ + L++ G D + +R Y AE++ ALE L
Sbjct: 883 ARNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIAEVVLALEYL 942
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM-------------------KDQEKT 537
H +++RDLKP+N+L+ + GH+ L DFGL K+ + +++ K
Sbjct: 943 HSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPKL 1002
Query: 538 TTF------CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKK 591
T GTP+YLAPE+LLG G+ DWW++G++LYE L G+PP+ + +++
Sbjct: 1003 PTLDHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVGIPPFNADHPQQIFDN 1062
Query: 592 ILQDPLRF---PDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMK 648
IL +++ P+D +A+DL+ LL DP +RLG G+ E+K H FF + W L +
Sbjct: 1063 ILNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQRLGARGAAEVKQHSFFKDIDWNTLAQQ 1122
Query: 649 GYIPPYKPPVMGAMDTSNFDQEFT 672
+ P A DTS F ++
Sbjct: 1123 K--AAFVPDSENAFDTSYFQSRYS 1144
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 236 bits (602), Expect = 9e-62
Identities = 121/311 (38%), Positives = 193/311 (61%), Gaps = 6/311 (1%)
Query: 370 KPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA 429
+P LS+D+F LL V+G+G FGKV+ + R N+ YA+KA++K I+++ EV L+
Sbjct: 251 QPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLS 310
Query: 430 ERTVLARVD---NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYT 486
E+ + + +PF+V L FQ+ + + V+ + GG+L H+ + + R+ FY
Sbjct: 311 EKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLE-PRAVFYA 369
Query: 487 AELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEY 546
A ++ L+ LH+ IIYRDLK +N+LLD +G++ + DFGLCK M ++T TFCGTPE+
Sbjct: 370 ACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEF 429
Query: 547 LAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKD 606
LAPE+L YT+ VDWW LGVL++EML G P+ +D +++ I+ D +R+P +
Sbjct: 430 LAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLE 489
Query: 607 AKDLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDT 664
A ++ LL ++P+RRLG ++++K FF + W L ++ PP+ P + D
Sbjct: 490 AIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDV 549
Query: 665 SNFDQEFTREQ 675
SNFD+EFT E+
Sbjct: 550 SNFDEEFTSEK 560
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 236 bits (602), Expect = 9e-62
Identities = 121/311 (38%), Positives = 193/311 (61%), Gaps = 6/311 (1%)
Query: 370 KPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA 429
+P LS+D+F LL V+G+G FGKV+ + R N+ YA+KA++K I+++ EV L+
Sbjct: 945 QPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLS 1004
Query: 430 ERTVLARVD---NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYT 486
E+ + + +PF+V L FQ+ + + V+ + GG+L H+ + + R+ FY
Sbjct: 1005 EKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLE-PRAVFYA 1063
Query: 487 AELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEY 546
A ++ L+ LH+ IIYRDLK +N+LLD +G++ + DFGLCK M ++T TFCGTPE+
Sbjct: 1064 ACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEF 1123
Query: 547 LAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKD 606
LAPE+L YT+ VDWW LGVL++EML G P+ +D +++ I+ D +R+P +
Sbjct: 1124 LAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLE 1183
Query: 607 AKDLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDT 664
A ++ LL ++P+RRLG ++++K FF + W L ++ PP+ P + D
Sbjct: 1184 AIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDV 1243
Query: 665 SNFDQEFTREQ 675
SNFD+EFT E+
Sbjct: 1244 SNFDEEFTSEK 1254
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 235 bits (600), Expect = 2e-61
Identities = 130/369 (35%), Positives = 205/369 (55%), Gaps = 56/369 (15%)
Query: 354 IELESKMGKLN----LSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYA 409
+ +E KM L ++Y + + +DDF+LL +IG+G+FG+V +++ T +YA
Sbjct: 88 VTVEDKMDILKNFEKKEMEYMRLQRQKMGVDDFELLSIIGRGAFGEVRICKEKSTGSVYA 147
Query: 410 LKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFY 469
+K ++KS ++ + +V H AER VLA VD+PFIV L +SFQ E LYL++ ++ GG++
Sbjct: 148 MKKLKKSEMLRRGQVEHVKAERNVLAEVDSPFIVKLCYSFQDDEHLYLIMEYLPGGDMMT 207
Query: 470 HLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK- 528
L R+ +RFY A+ + A+E++H + ++RD+KP+N+L+ GHI L DFGL K
Sbjct: 208 LLMRKDTLREDETRFYVAQTILAIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLSKS 267
Query: 529 ------------------------------------------LNMKDQEKTTTF--CGTP 544
L+ + +T F GTP
Sbjct: 268 LESKNFPDFKAELVDRSTKPAAEHDRLSKPPSAPRRTQQEQLLHWQQNRRTLAFSTVGTP 327
Query: 545 EYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD 602
+Y+APE+LL +GY DWW+LG +++EML G PP+Y E+ +KI+ + L+FPD+
Sbjct: 328 DYIAPEVLLKKGYGMECDWWSLGAIMFEMLVGFPPFYSEEPLATCRKIVNWKTCLKFPDE 387
Query: 603 --FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMG 660
+ KDL+ LLC + ++RLG G EIK+HP+F + W+RL PY P V
Sbjct: 388 AKLSIEVKDLIRRLLC-NVEQRLGTKGVHEIKAHPWFRGVEWERLYESN--APYIPQVKH 444
Query: 661 AMDTSNFDQ 669
+DT NF++
Sbjct: 445 ELDTQNFEK 453
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 235 bits (599), Expect = 2e-61
Identities = 125/332 (37%), Positives = 188/332 (55%), Gaps = 39/332 (11%)
Query: 371 PSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
P SI+DF+++K I +G+FG+V +KR T ++A+K ++K+ ++ K+ V LAE
Sbjct: 743 PRAKDRTSIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAE 802
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
R +L V NPF+V +SF E LYLV+ ++NGG+LF L+ G D +R Y AE++
Sbjct: 803 RNILISVRNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVV 862
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM------------------- 531
ALE LH +II+RDLKP+N+L++ GHI L DFGL K+ +
Sbjct: 863 LALEYLHSVNIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFF 922
Query: 532 ------------KDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPP 579
KD K GTP+YLAPE+LLG G+ K DWW++GV+L+E+L G+PP
Sbjct: 923 AEDGSKAQHSQGKDSRKKHAVVGTPDYLAPEILLGMGHGKTADWWSVGVILFEVLVGIPP 982
Query: 580 YYDEDVPKMYKKILQDPL---RFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPF 636
+ E ++++ I+ + P++ +A DL+ LL +P +RLG G+ E+K H F
Sbjct: 983 FNAETPQQIFENIINRDIPWPNVPEEISYEAHDLINKLLTENPVQRLGATGAGEVKQHHF 1042
Query: 637 FNQLSWKRL-KMKGYIPPYKPPVMGAMDTSNF 667
F ++W L + K P P DTS F
Sbjct: 1043 FKDINWDTLARQKAMFVPSAEP----QDTSYF 1070
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 234 bits (597), Expect = 3e-61
Identities = 137/393 (34%), Positives = 215/393 (53%), Gaps = 54/393 (13%)
Query: 368 DYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHT 427
+Y + DDF+ L +IGKG+FG+V R++ T +YA+K ++KS ++ + +V H
Sbjct: 29 EYMRRQRHKMGADDFEPLTMIGKGAFGEVRICREKGTGNVYAMKKLKKSEMLRRGQVEHV 88
Query: 428 LAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTA 487
AER +LA VD+ IV L SFQ E LYL++ ++ GG++ L R+ +RFY
Sbjct: 89 KAERNLLAEVDSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYIG 148
Query: 488 ELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK----LNMKDQEKTT----- 538
E + A+E++H + I+RD+KP+N+LLD GH+ L DFGLCK N+++++ T
Sbjct: 149 ETVLAIESIHKHNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCSNLQEKDFTVARNVS 208
Query: 539 --------------------------------TFCGTPEYLAPELLLGQGYTKVVDWWTL 566
+ GTP+Y+APE+LL +GY DWW+L
Sbjct: 209 GALQSDGRPVATRRTQQEQLLNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSL 268
Query: 567 GVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRR 622
G ++YEML G PP+Y +D +KI+ ++ L+FPD+ +AKDL+ LLC + ++R
Sbjct: 269 GAIMYEMLVGFPPFYSDDPMTTCRKIVNWRNYLKFPDEVRLSPEAKDLICRLLC-NVEQR 327
Query: 623 LGYHGSDEIKSHPFFNQLSWKRL-KMKGYIPPYKPPVMGAMDTSNFD--QEFTREQPVDS 679
LG G+DEIK HP+F W +L +MK + P V +DT NF+ +E ++ P +
Sbjct: 328 LGTKGADEIKGHPWFRGTEWGKLYQMKA---AFIPQVNDELDTQNFEKFEETDKQVPKSA 384
Query: 680 VVNDF--LSESVQQQFGGWTYVGSEQLGQSMLP 710
+ + S F G+TY E + +P
Sbjct: 385 KSGPWRKMLSSKDINFVGYTYKNVEIVNDDQIP 417
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 234 bits (596), Expect = 4e-61
Identities = 117/298 (39%), Positives = 179/298 (59%), Gaps = 5/298 (1%)
Query: 373 THKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERT 432
T + S+ + + IGKG+FG+V R + T YALK + +V + H E+
Sbjct: 54 TRESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKR 113
Query: 433 VLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
VL ++ +PFIV + S + S LY+++ F+ GGE+F +L+ F S +RFY +E++CA
Sbjct: 114 VLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCA 173
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELL 552
LE +H I+YRDLKPEN++L +GHI + DFG K + +++T T CGTP+YLAPE L
Sbjct: 174 LEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK---ELRDRTYTICGTPDYLAPESL 230
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
G+ K VDWW LG+L+YEM+ G PP+ + ++Y I++ L+FP F+ AKDL+
Sbjct: 231 ARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVK 290
Query: 613 GLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
LL D +R+G +G+ ++K H +F +++W PP P + DT NFD
Sbjct: 291 KLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFD 348
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 232 bits (592), Expect = 1e-60
Identities = 134/381 (35%), Positives = 205/381 (53%), Gaps = 62/381 (16%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+S+DDF+LL +IG+G+FG+V R+R + IYA+K ++KS +V + +V H AER +LA
Sbjct: 89 ISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMVMRGQVEHVRAERNLLAE 148
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
V++ +IV L +SFQ E LYL++ ++ GG++ L RE +RFY A+ + A+E++
Sbjct: 149 VESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLREDVARFYIAQSVLAIESI 208
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCK---------------------------- 528
H ++ I+RD+KP+N+LLD GH+ L DFGLCK
Sbjct: 209 HRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQENRATDDETMSEPMDVD 268
Query: 529 ---------------------LNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLG 567
M ++ + GTP+Y+APE+LL +GY DWW+LG
Sbjct: 269 RCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDYIAPEVLLKKGYGMECDWWSLG 328
Query: 568 VLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRL 623
++YEML G PP+Y +D +KI+ ++ L+FP+D F +AKDL+ LLC R
Sbjct: 329 AIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPEDAKFSSEAKDLICRLLCNVDHRLG 388
Query: 624 GYHGSDEIKSHPFFNQLSWKRL-KMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDSVVN 682
G+ +IK HP+F + W++L +M+ YKP V +DT NF + P
Sbjct: 389 TGGGAQQIKDHPWFKDVVWEKLYEMEA---AYKPEVNDELDTQNFMKFDEVNSPAPERTR 445
Query: 683 DFLSESV-----QQQFGGWTY 698
LS + F G+TY
Sbjct: 446 SGLSRKMLLAPKDLSFVGYTY 466
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 231 bits (590), Expect = 2e-60
Identities = 132/360 (36%), Positives = 212/360 (58%), Gaps = 23/360 (6%)
Query: 369 YKPSTHK----HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEV 424
YK + +K + +D++++KVIG+G+FG+V VR + T K+YA+K + K ++ +S+
Sbjct: 59 YKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDS 118
Query: 425 THTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR--S 482
ER ++A ++P++V L ++FQ LY+V+ ++ GG+L + +D+ +
Sbjct: 119 AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDL---VNLMSNYDVPEKWA 175
Query: 483 RFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDQEKTTTFC 541
RFYTAE++ AL+A+H I+RD+KP+N+LLD GH+ L DFG C K+N + + T
Sbjct: 176 RFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAV 235
Query: 542 GTPEYLAPELLLGQG----YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QD 595
GTP+Y++PE+L QG Y + DWW++GV LYEML G P+Y + + Y KI+ ++
Sbjct: 236 GTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKN 295
Query: 596 PLRFPDDFD--KDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
L FPDD D K+AK+L+ L D + RLG +G +EIK H FF W ++ + P
Sbjct: 296 SLTFPDDNDISKEAKNLICAFL-TDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAP 354
Query: 654 YKPPVMGAMDTSNFD--QEFTREQPVDSVVNDFLSESVQQQFGGWTYVGSEQLGQSMLPD 711
P + +DTSNFD +E E+ + F+ Q F G+TY + + S P+
Sbjct: 355 VVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFVGN--QLPFVGFTYYSNRRYLSSANPN 412
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 231 bits (590), Expect = 2e-60
Identities = 130/350 (37%), Positives = 199/350 (56%), Gaps = 51/350 (14%)
Query: 368 DYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHT 427
+Y + + IDDF+LL VIGKG+FG+V R R T+++YA+K ++K+ ++S+ +V H
Sbjct: 88 EYMRLQRRKIGIDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKKTEMLSRGQVEHV 147
Query: 428 LAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTA 487
+ER +LA VD+ +IV L +SFQ SE LYL++ ++ GG++ L RE +RFY A
Sbjct: 148 RSERNLLAEVDSRYIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMREDILSEDVARFYIA 207
Query: 488 ELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK--------LNMKDQEKTT- 538
E + A+ ++H + ++RD+KP+N++LD GH+ L DFGLCK L ++D E +
Sbjct: 208 ESILAIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLCKPLDDKYSSLLLEDDEMLSQ 267
Query: 539 -----------------------------------TFCGTPEYLAPELLLGQGYTKVVDW 563
+ GT +Y+APE+LL +GY DW
Sbjct: 268 DSENQSGKSDADKAPWQMPKEQLLQWKRNRRALAYSTVGTLDYMAPEVLLKKGYGMECDW 327
Query: 564 WTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDP 619
W+LG +LYEML G PP+ +D +KI+ + L+FP++ +A+DL+ LLC D
Sbjct: 328 WSLGAILYEMLVGYPPFCSDDPRITCRKIINWRVCLKFPEEPKISDEARDLICRLLC-DV 386
Query: 620 KRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
RLG G +EIKSHP+F W K+ Y+P V G +DT NF++
Sbjct: 387 DSRLGTRGVEEIKSHPWFKGTPWD--KLYDMEAAYRPIVDGELDTQNFEK 434
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 230 bits (586), Expect = 6e-60
Identities = 128/331 (38%), Positives = 192/331 (57%), Gaps = 11/331 (3%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSE-VTHTLAERTVLARVDN 439
DF L V+G+GS+GKV+ V++++T +++A K ++K+ IV +++ + T ER +L V +
Sbjct: 90 DFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRH 149
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
PFI L ++FQ ++LYL+L + GGELF HL + FYTAEL AL LH
Sbjct: 150 PFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKL 209
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTK 559
I+YRDLKPEN LLD +GHI L DFGL K+ ++ +F GT EY APE+LL Q Y
Sbjct: 210 GIVYRDLKPENCLLDAEGHILLTDFGLSKV-AENGADCRSFVGTEEYCAPEILLEQPYDH 268
Query: 560 VVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDP 619
VDWW++G+L++++LTG PP+ + ++ +KI + P DA+D++ L ++P
Sbjct: 269 AVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARDIINKFLKKNP 328
Query: 620 KRRLGYHGS----DEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTR-- 673
K+RLG G D IK H + ++ W +L+ + PP P + NF EFT+
Sbjct: 329 KQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENFSVEFTKLP 388
Query: 674 --EQPV-DSVVNDFLSESVQQQFGGWTYVGS 701
P+ + S F G+TYV S
Sbjct: 389 LSTTPILHEEFGNLTIGSHSSAFQGFTYVAS 419
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 230 bits (586), Expect = 6e-60
Identities = 136/384 (35%), Positives = 210/384 (54%), Gaps = 51/384 (13%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
HK L + DFDLL +IGKG+FG+V R++ T ++YA+K ++K+ ++ + +V H AER +
Sbjct: 117 HK-LGVADFDLLTMIGKGAFGEVRVCREKTTGQVYAMKKLKKAEMLRRGQVEHVRAERNL 175
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
LA VD+ +IV L SFQ + LYLV+ ++ GG++ L R+ ++FY AE + A+
Sbjct: 176 LAEVDSNYIVKLYCSFQDDDHLYLVMEYLPGGDMMTLLMRKDTLTEEEAKFYVAETVLAI 235
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK----------------LNMKDQEKT 537
E++H + I+RD+KP+N+LLD GH+ L DFGLCK +QE
Sbjct: 236 ESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSAIGENDFSNNSNGSTEQEAG 295
Query: 538 TT-----------------------FCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEML 574
+T GTP+Y+APE+LL +GY DWW+LG ++YEML
Sbjct: 296 STAPKRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEML 355
Query: 575 TGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGSDE 630
G PP+Y +D +KI+ + L+FP++ ++AKDL+ LLC +RRLG G+DE
Sbjct: 356 VGYPPFYSDDPMSTCRKIVNWKSHLKFPEEAILSREAKDLINSLLC-SVRRRLGSKGADE 414
Query: 631 IKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ--EFTREQPVDSVVNDF--LS 686
+K+H +F + W + + P V +DT NF++ E E S + +
Sbjct: 415 LKAHTWFETVDWDTI--FDMDAAFVPEVNDDLDTQNFEKFDESESETQTSSKSGPWRKML 472
Query: 687 ESVQQQFGGWTYVGSEQLGQSMLP 710
S F G+TY E + +P
Sbjct: 473 SSKDINFVGYTYKNFEIVNDYQVP 496
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 229 bits (585), Expect = 8e-60
Identities = 139/384 (36%), Positives = 205/384 (53%), Gaps = 47/384 (12%)
Query: 368 DYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHT 427
DY L+++DF+ LKVIG+G+FG+V V+K DT IYA+K +RKS +V K + H
Sbjct: 66 DYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHV 125
Query: 428 LAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTA 487
AER +L+ D ++V + +SFQ LYLV+ F+ GG++ L ++ ++FY A
Sbjct: 126 RAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQFYIA 185
Query: 488 ELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLC----KLNMKD---------- 533
E A++ +H I+RD+KP+N+LLD +GH+ L DFGLC K + D
Sbjct: 186 EAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWPSTLP 245
Query: 534 ----------QEKTTTF-----------CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYE 572
+ K T+ GTP+Y+APE+ GYTK DWW+LGV++YE
Sbjct: 246 PDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYE 305
Query: 573 MLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGS 628
ML G PP+ E + Y+K++ Q L FP D +AK I C + +RRLG HG
Sbjct: 306 MLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAK-ATIKRFCCEAERRLGNHGG 364
Query: 629 -DEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQ---PVDSVVNDF 684
DEIK PF ++ W ++ + PP + V DTSNFD +F E P +++
Sbjct: 365 LDEIKQCPFVKRIDWNHIRERP--PPIRVTVKSIDDTSNFD-DFPDEDLTWPTSTLIRPE 421
Query: 685 LSESVQQQFGGWTYVGSEQLGQSM 708
+ +F +TY + L Q M
Sbjct: 422 EQPGRRGEFVDFTYKRFDGLTQKM 445
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 228 bits (580), Expect = 3e-59
Identities = 136/395 (34%), Positives = 213/395 (53%), Gaps = 56/395 (14%)
Query: 368 DYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHT 427
+Y + DDF+ L +IGKG+FG+V R++ T +YA+K ++KS ++ + +V H
Sbjct: 106 EYMRRQRHKMGTDDFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRGQVEHV 165
Query: 428 LAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTA 487
AER +LA VD+ IV L SFQ E LYL++ ++ GG++ L R+ +RFY
Sbjct: 166 KAERNLLAEVDSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYVG 225
Query: 488 ELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK------LNMKD-------- 533
E + A+E++H + I+RD+KP+N+LLD GH+ L DFGLCK L KD
Sbjct: 226 ETVLAIESIHKHNYIHRDIKPDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAHNLS 285
Query: 534 -----------------------------QEKTTTFCGTPEYLAPELLLGQGYTKVVDWW 564
+ + GTP+Y+APE+LL +GY DWW
Sbjct: 286 GALQSDGRPVAPRRTRSQMEQLQNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWW 345
Query: 565 TLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPK 620
+LG ++YEML G PP+Y ++ +KI+ ++ L+FPD+ +AKDL+ LLC + +
Sbjct: 346 SLGAIMYEMLVGFPPFYSDEPMTTCRKIVNWKNYLKFPDEVRLSPEAKDLICRLLC-NVE 404
Query: 621 RRLGYHGSDEIKSHPFFNQLSWKRL-KMKGYIPPYKPPVMGAMDTSNFD--QEFTREQPV 677
+R+G G++EIK HP+F+ + W++L +MK + P V +DT NF+ +E + P
Sbjct: 405 QRIGTKGANEIKEHPWFSGVEWEKLYQMKA---AFIPQVNDELDTQNFEKFEEVKTKIPK 461
Query: 678 DSVVNDF--LSESVQQQFGGWTYVGSEQLGQSMLP 710
+ + S F G+TY E + LP
Sbjct: 462 TPKSGPWRKMLSSKDINFVGYTYKNVEIVNHDQLP 496
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 227 bits (579), Expect = 4e-59
Identities = 141/417 (33%), Positives = 221/417 (52%), Gaps = 75/417 (17%)
Query: 353 WIELESKMGKLNLS---------------VDYKPSTHKHLSIDDFDLLKVIGKGSFGKVM 397
W+ LE K+ L++S +Y L +DDFDLL +IG+G+FG+V
Sbjct: 62 WV-LEQKIASLDVSEKEQLELLEDLQRKETEYTRLMRNRLCVDDFDLLSIIGRGAFGEVR 120
Query: 398 QVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYL 457
R++ T IYA+K ++KS ++S+ +V H AER +LA V + IV L +SFQ E LYL
Sbjct: 121 LCREKKTGNIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVASDCIVKLYYSFQDPEYLYL 180
Query: 458 VLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQG 517
++ +++GG++ L RE + +RFY A+ + A+E++H + ++RD+KP+N+LLD G
Sbjct: 181 IMEYLSGGDVMTLLMREETLTETVARFYIAQSVLAIESIHKHNYVHRDIKPDNLLLDKYG 240
Query: 518 HIALCDFGLCK---------LNMKD----------------------------------- 533
H+ L DFGLCK +N+ +
Sbjct: 241 HMKLSDFGLCKPLDCRNISAMNVNEPLNDENINESIDGDENCSIGRRGRRWKSPLEQLQH 300
Query: 534 -----QEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKM 588
++ + GTP+Y+APE+LL +GY DWW+LG ++YEML G PP+Y +D
Sbjct: 301 WQINRRKLAYSTVGTPDYIAPEVLLKKGYGVECDWWSLGAIMYEMLVGYPPFYSDDPVTT 360
Query: 589 YKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYH--GSDEIKSHPFFNQLSW 642
+KI+ + L FP+ +A+DL+ LLC D + RLG H G+++IK+H +F + W
Sbjct: 361 CRKIVSWRTHLVFPEGARLTPEARDLICRLLC-DSEHRLGSHGAGAEQIKAHTWFKDVEW 419
Query: 643 KRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYV 699
++L +KP V G +DT NF + E P + S V QF G +Y+
Sbjct: 420 EKLYEMD--AAFKPVVNGELDTQNFMKFDEVECPKPARTGSGPSWKV-LQFSGKSYI 473
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 227 bits (578), Expect = 5e-59
Identities = 146/418 (34%), Positives = 210/418 (49%), Gaps = 84/418 (20%)
Query: 351 HHWIELESKMGKLNLSVDYKPSTHKHLSIDD---------------FDLLKVIGKGSFGK 395
H +LE++M ++ LS D + K L + F +K +G G+FG+
Sbjct: 659 HRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGE 718
Query: 396 VMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKL 455
V RK DT +YA K +RK ++ +++V H AER +LA DN ++V L +SFQ + L
Sbjct: 719 VCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNL 778
Query: 456 YLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDY 515
Y V+ +I GG++ L R G F S +RFY AEL CA+E++H I+RD+KP+NIL+D
Sbjct: 779 YFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDR 838
Query: 516 QGHIALCDFGLC---------------------KLNMKDQEKTTTFC------------- 541
GHI L DFGLC ++ ++ + C
Sbjct: 839 DGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRA 898
Query: 542 -------------GTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKM 588
GTP Y+APE+LL GYT++ DWW++GV+L+EML G PP+ + +
Sbjct: 899 ARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLET 958
Query: 589 YKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWK- 643
K++ Q L P +A DL+I LCR P+ RLG +G+DEIK+HPFF + +
Sbjct: 959 QMKVINWQTSLHIPPQAKLSPEASDLII-KLCRGPEDRLGKNGADEIKAHPFFKTIDFSS 1017
Query: 644 --RLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDS---VVNDFLSESVQQQFGGW 696
R + YIP P DTSNFD PVD +D E+V GW
Sbjct: 1018 DLRQQSASYIPKITHPT----DTSNFD-------PVDPDKLWSDDNEEENVNDTLNGW 1064
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 225 bits (574), Expect = 2e-58
Identities = 118/332 (35%), Positives = 191/332 (56%), Gaps = 42/332 (12%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
L ++DF+ LKVIG+G+FG+V V+K+DT +YA+K +RK+ ++ K +V H AER +L
Sbjct: 84 LGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVE 143
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
D+ ++V + +SFQ LYL++ F+ GG++ L ++ ++FY AE + A++++
Sbjct: 144 ADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSI 203
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCK------------------------LNMK 532
H I+RD+KP+N+LLD +GH+ L DFGLC NM
Sbjct: 204 HQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMN 263
Query: 533 DQEKTTTF-----------CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYY 581
+ K T+ GTP+Y+APE+ + GY K+ DWW+LGV++YEML G PP+
Sbjct: 264 SKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFC 323
Query: 582 DEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFF 637
E + YKK++ ++ L FP + + AKDL++ C + + R+G G +EIKS+ FF
Sbjct: 324 SETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCC-EWEHRIGAPGVEEIKSNSFF 382
Query: 638 NQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
+ W+ ++ + + DTSNFD+
Sbjct: 383 EGVDWEHIRERP--AAISIEIKSIDDTSNFDE 412
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 223 bits (567), Expect = 1e-57
Identities = 114/329 (34%), Positives = 186/329 (55%), Gaps = 36/329 (10%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV 437
SIDDF+++K I +G+FG+V +KR T ++A+K ++K+ ++ K+ V LAER +L V
Sbjct: 886 SIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNAVESILAERDILINV 945
Query: 438 DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
NPF+V +SF + LYLV+ ++NGG+L+ L+ G + R Y AE++ ALE LH
Sbjct: 946 RNPFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLALEYLH 1005
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM-------------------------- 531
+++RDLKP+N+L+ + GHI L DFGL K+ +
Sbjct: 1006 SEGVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLA 1065
Query: 532 -----KDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVP 586
++ K + GTP+YLAPE+LLG G+ DWW++G++L+E++ G+PP+ E
Sbjct: 1066 ASEEQLERRKKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILFELIVGIPPFNAEHPQ 1125
Query: 587 KMYKKILQDPL---RFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWK 643
+++ IL + P++ +A D++ L DP +RLG G+ E+K H FF ++W
Sbjct: 1126 QIFDNILNRKIPWPHVPEEMSAEAHDIIDRFLTEDPHQRLGARGAAEVKQHIFFKDINWD 1185
Query: 644 RLKMKGYIPPYKPPVMGAMDTSNFDQEFT 672
L + + P A+DTS F ++
Sbjct: 1186 TLARQK--AAFVPASESAIDTSYFRSRYS 1212
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 222 bits (565), Expect = 2e-57
Identities = 135/385 (35%), Positives = 213/385 (55%), Gaps = 52/385 (13%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
HK + DDF+LL +IGKG+FG+V VR+ +T ++A+K ++KS ++ + +V H AER +
Sbjct: 130 HK-MGADDFELLTMIGKGAFGEVRVVREINTGHVFAMKKLKKSEMLRRGQVEHVRAERNL 188
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
LA VD+ IV L SFQ +E LYL++ ++ GG++ L R+ ++FY AE + A+
Sbjct: 189 LAEVDSNCIVKLYCSFQDNEYLYLIMEYLPGGDMMTLLMRKDTLSEDEAKFYIAESVLAI 248
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK---LNMKDQEKTT------------ 538
E++H+ + I+RD+KP+N+LLD GH+ L DFGLCK ++ D E T
Sbjct: 249 ESIHNRNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSVIDGEDFTVGNAGSGGGSES 308
Query: 539 -------------------------TFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEM 573
+ GTP+Y+APE+LL +GY DWW+LG ++YEM
Sbjct: 309 VSTTPKRSQQEQLEHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEM 368
Query: 574 LTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGSD 629
L G PP+Y +D +KI+ + L+FP++ + A+DL+ LLC +RLG G+
Sbjct: 369 LVGYPPFYADDPMSTCRKIVNWKTHLKFPEESRLSRGARDLIGKLLC-SVNQRLGSTGAS 427
Query: 630 EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSN---FDQEFTREQ-PVDSVVNDFL 685
+IK+HP+F + W+++ + P V +DT N FD+E + Q P + +
Sbjct: 428 QIKAHPWFEGVQWEKIYQME--AAFIPEVNDDLDTQNFEKFDEEDNQTQAPSRTGPWRKM 485
Query: 686 SESVQQQFGGWTYVGSEQLGQSMLP 710
S F G+TY E + +P
Sbjct: 486 LSSKDINFVGYTYKNFEIVNDYQVP 510
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 221 bits (564), Expect = 2e-57
Identities = 120/309 (38%), Positives = 180/309 (57%), Gaps = 6/309 (1%)
Query: 373 THKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERT 432
T K + DF L V+G+G FGKV+ V+ + T K YA+KA++K ++S+ E+ E+
Sbjct: 550 TRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKR 609
Query: 433 VLARVD---NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAEL 489
+L V +PF++ L FQ+S V F+ GG+L + E F ++RFY A +
Sbjct: 610 ILEAVGCTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIH-EDVFPEPQARFYVACV 668
Query: 490 LCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAP 549
+ L+ LH+ IIYRDLK +N+LLD QG + + DFGLCK + ++T+TFCGTPE+LAP
Sbjct: 669 VLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAP 728
Query: 550 ELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKD 609
E+L + YT+ VDWW LGVLLYEML G P+ + +++ I+ +P +
Sbjct: 729 EVLTQEAYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLE 788
Query: 610 LLIGLLCRDPKRRL--GYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNF 667
+ LL + P++RL G ++EIK PFF +W+ L + PP+ P + G D F
Sbjct: 789 FIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYF 848
Query: 668 DQEFTREQP 676
+ EFT P
Sbjct: 849 EGEFTGLPP 857
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 221 bits (564), Expect = 2e-57
Identities = 127/311 (40%), Positives = 189/311 (59%), Gaps = 10/311 (3%)
Query: 376 HLSIDDFDLLKVIGKGSFGKVMQVR-KRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
+L + DF+++ +G G FG+V V+ K + +K +A+K ++K +IV + H +E+ ++
Sbjct: 369 NLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIM 428
Query: 435 ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
+ FIV L +F+ S+ LY+++ GGEL+ L+ G F+ S +RFYTA ++ A
Sbjct: 429 QGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFA 488
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
LH IIYRDLKPEN++LD++G+ L DFG K + +KT TFCGTPEY+APE++L
Sbjct: 489 YLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAK-KIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ--DPLRFPDDFDKDAKDLLI 612
+G+ D+W+LG+L+YE+LTG PP+ D K Y IL+ D + FP K+A + LI
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAAN-LI 606
Query: 613 GLLCRD-PKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
LCRD P RLG +G +I+ H +F +W+ L+ PP P V DTSNFD
Sbjct: 607 KKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDS 666
Query: 670 --EFTREQPVD 678
E E P D
Sbjct: 667 FPEDNDEPPPD 677
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 220 bits (561), Expect = 5e-57
Identities = 119/310 (38%), Positives = 178/310 (57%), Gaps = 11/310 (3%)
Query: 371 PSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
PST +DD+++ +G GSFGKV VR+R++ YA K + K IV +V+H ++E
Sbjct: 40 PST----GLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSE 95
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+ VL + P V L S++ + LYLVL I GGELF + ++ +F ++RFY A++
Sbjct: 96 KNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVF 155
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
ALE LH ++YRDLKPENI++D G++ + DFG K K + +T T CGTPEYL PE
Sbjct: 156 LALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAK---KVETRTMTLCGTPEYLPPE 212
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPY--YDEDVPKMYKKILQDPLRFPDDFDKDAK 608
++ + Y VDWW GVL++E + G P+ ++ DV MY KI + + P F +
Sbjct: 213 IIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALR 272
Query: 609 DLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSN 666
L+ LL D +R G +G+ +IK H +F + W L + PY P + D SN
Sbjct: 273 HLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISN 332
Query: 667 FDQEFTREQP 676
FD+ + +P
Sbjct: 333 FDKVSDKPRP 342
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 220 bits (560), Expect = 7e-57
Identities = 125/306 (40%), Positives = 179/306 (57%), Gaps = 17/306 (5%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
LS DDF++LKVIGKG+FG+V VR R +IYA+K + K +V ++E ER VL
Sbjct: 78 LSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVY 137
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQR-EGRFDLSRSRFYTAELLCALEA 495
D +I L ++FQ + LY V+ + GG++ L + S ++FY AE++ A+++
Sbjct: 138 GDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDS 197
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFC-GTPEYLAPELLL- 553
LH ++RD+KP+N+LLD QGHI L DFG C + D + GTP+Y++PE+L
Sbjct: 198 LHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVAVGTPDYISPEILRA 257
Query: 554 ---GQG-YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD----- 602
G+G Y K DWW+LG+ +YEML G P+Y E + Y KI+ QD L FPDD
Sbjct: 258 MEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWV 317
Query: 603 FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
++AKDL+ L+C R G +G + + HPFF + W ++ PPY P V
Sbjct: 318 VSEEAKDLIRQLICSSDV-RFGRNGLSDFQLHPFFEGIDWNTIRDSN--PPYVPEVSSPE 374
Query: 663 DTSNFD 668
DTSNFD
Sbjct: 375 DTSNFD 380
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 220 bits (560), Expect = 7e-57
Identities = 118/355 (33%), Positives = 193/355 (54%), Gaps = 44/355 (12%)
Query: 357 ESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKS 416
E ++ +Y L ++DF+ LKVIG+G+FG+V V+K+DT +YA+K +RK+
Sbjct: 68 EKRLQHAQKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKA 127
Query: 417 YIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR 476
++ K +V H AER VL D+ ++V + +SFQ LYL++ F+ GG++ L ++
Sbjct: 128 DMLEKEQVAHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDT 187
Query: 477 FDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLC----KLNMK 532
++FY +E A++++H I+RD+KP+N+LLD +GH+ L DFGLC K +
Sbjct: 188 LSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRT 247
Query: 533 D------QEKTTTF----------------------------CGTPEYLAPELLLGQGYT 558
D Q K + F GTP+Y+APE+ L GY
Sbjct: 248 DFYRDLSQAKPSDFIGTCASPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYG 307
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGL 614
DWW+LGV++YEML G PP+ ++ Y+K++ ++ L FP + ++AK+ +I
Sbjct: 308 PACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINF 367
Query: 615 LCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
C +R G +++KS PFF + W+ ++ + P + V DTSNFD+
Sbjct: 368 CCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVE--VRSIDDTSNFDE 420
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 219 bits (559), Expect = 9e-57
Identities = 123/315 (39%), Positives = 187/315 (59%), Gaps = 19/315 (6%)
Query: 370 KPSTHK----HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVT 425
KP T K L +DF++LKVIG+G+FG+V V+ ++ +K++A+K + K ++ ++E
Sbjct: 61 KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA 120
Query: 426 HTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQR-EGRFDLSRSRF 484
ER VL DN +I L ++FQ LYLV+ + GG+L L + E R +RF
Sbjct: 121 CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF 180
Query: 485 YTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKD-QEKTTTFCGT 543
Y AE++ A++++H ++RD+KP+NIL+D GHI L DFG C M+D +++ GT
Sbjct: 181 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT 240
Query: 544 PEYLAPELLL----GQG-YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLR 598
P+Y++PE+L G+G Y DWW+LGV +YEML G P+Y E + + Y KI+ R
Sbjct: 241 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER 300
Query: 599 FP-----DDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
F D ++AKDL+ L+C + RLG +G ++ K HPFF+ + W + + P
Sbjct: 301 FQFPAQVTDVSENAKDLIRRLIC-SREHRLGQNGIEDFKKHPFFSGIDWDNI--RNCEAP 357
Query: 654 YKPPVMGAMDTSNFD 668
Y P V DTSNFD
Sbjct: 358 YIPEVSSPTDTSNFD 372
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 219 bits (558), Expect = 1e-56
Identities = 122/313 (38%), Positives = 184/313 (57%), Gaps = 29/313 (9%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F+ ++++G+G GKV +R+RDTN+I+ALK + K ++ + ++ L E+ +LA D+PF
Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPF 383
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR--SRFYTAELLCALEALHDF 499
IV L SFQ+ + LYL + + GGE F LQ ++ ++FY +E++ ALE LH
Sbjct: 384 IVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLL 443
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLC-------KLNMKDQE-----------KTTTFC 541
IYRDLKPENILL GH+ L DF L K MKD +T +F
Sbjct: 444 GFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFV 503
Query: 542 GTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPD 601
GT EYLAPE++ G G+T VDWWTLG+L+YEML G P+ ++ + + IL ++FP
Sbjct: 504 GTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPH 563
Query: 602 D--FDKDAKDLLIGLLCRDPKRRLG-YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV 658
D K+ KDL+ LL ++ +RLG G+ +IK HPFF ++ W L+ + PP+
Sbjct: 564 DKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQ------DPPL 617
Query: 659 MGAMDTSNFDQEF 671
+ A++ + + F
Sbjct: 618 IPALNDNGCELPF 630
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 218 bits (556), Expect = 2e-56
Identities = 133/373 (35%), Positives = 199/373 (52%), Gaps = 54/373 (14%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
LS++DF +KVIGKG+FG+V V+K DT KIYA+K++ K+ + + ++ H AER +L
Sbjct: 88 LSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVE 147
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
D+P++V L ++FQ S LYL++ F+ GG+L L F +RFY AE + A+ +
Sbjct: 148 SDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADV 207
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCK---------------------------- 528
H I+RD+KP+NIL+D GHI L DFGL
Sbjct: 208 HRMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDA 267
Query: 529 --LNMKDQEKTTTF-----------CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLT 575
L M ++K T+ GTP+Y+APE+ L QGY + DWW+LG +++E L
Sbjct: 268 IWLTMSSKDKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLI 327
Query: 576 GLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGSDEI 631
G PP+ E+ + Y+KI+ ++ L FP+D +A+DL+ L+ D + RLG G+ EI
Sbjct: 328 GWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLM-TDSEHRLGRGGAIEI 386
Query: 632 KSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNF---DQEFTREQPV---DSVVNDFL 685
HPFF + W ++ P+ P + DT F + E EQPV + V+
Sbjct: 387 MQHPFFTGIDWDHIRETA--APFIPNLKSITDTHYFPVDELEQVPEQPVTQQPASVDPQT 444
Query: 686 SESVQQQFGGWTY 698
E F G+TY
Sbjct: 445 LEQTNLAFLGYTY 457
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 218 bits (556), Expect = 2e-56
Identities = 127/364 (34%), Positives = 196/364 (52%), Gaps = 32/364 (8%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DF+ +K+I G++G V VR RDT + +A+K I K ++ ++++ ER +L +NP
Sbjct: 196 DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENP 255
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
F+V + SF++ L +V+ ++ GG+ L+ G + +R Y AE + ALE LH++
Sbjct: 256 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYG 315
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCKLNM-------------KDQEK--TTTFCGTPE 545
I++RDLKP+N+L+ GHI L DFGL K+ + KD + CGTPE
Sbjct: 316 IVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPE 375
Query: 546 YLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD--- 602
Y+APE++ QGY K VDWW +GV+LYE L G P++ + +++ +++ D + +P+
Sbjct: 376 YIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEA 435
Query: 603 FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
DA+DL+ LL + P RLG G+ E+K HPFF L W L + + P +
Sbjct: 436 LPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLR--HKAEFVPQLEAED 493
Query: 663 DTSNFDQEFTREQPV---DSVVNDFLSESVQQQFGGWT------YVGSEQLGQSMLP--- 710
DTS FD R + + D ND S + QF + Y SE L P
Sbjct: 494 DTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFA 553
Query: 711 DRSF 714
+RSF
Sbjct: 554 ERSF 557
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 218 bits (555), Expect = 3e-56
Identities = 125/313 (39%), Positives = 181/313 (56%), Gaps = 18/313 (5%)
Query: 376 HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA 435
HL+++DF + ++IG+G FG+V RKRDT K+YA+K + K I K T L ER +L+
Sbjct: 185 HLTMNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRIKMKQGETLALNERIMLS 244
Query: 436 RV---DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
V D PFIV + ++F + +KL +L +NGG+L YHL + G F + RFY AE++
Sbjct: 245 LVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILG 304
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGL-CKLNMKDQEKTTTFCGTPEYLAPEL 551
LE +H+ ++YRDLKP NILLD GH+ + D GL C + K K GT Y+APE+
Sbjct: 305 LEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKK---KPHASVGTHGYMAPEV 361
Query: 552 L-LGQGYTKVVDWWTLGVLLYEMLTGLPPYYD---EDVPKMYKKILQDPLRFPDDFDKDA 607
L G Y DW++LG +L+++L G P+ +D ++ + L + PD F +
Sbjct: 362 LQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPEL 421
Query: 608 KDLLIGLLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPP-----VMG 660
LL GLL RD RRLG G+ E+K PFF L W+ + ++ Y PP PP
Sbjct: 422 HSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIPPRGEVNAAD 481
Query: 661 AMDTSNFDQEFTR 673
A D +FD+E T+
Sbjct: 482 AFDIGSFDEEDTK 494
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 216 bits (551), Expect = 7e-56
Identities = 117/301 (38%), Positives = 183/301 (59%), Gaps = 15/301 (4%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
+DF+++KVIG+G+FG+V V+ ++T +IYA+K + K ++ ++E ER VL D
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQR-EGRFDLSRSRFYTAELLCALEALHD 498
+I L ++FQ LYLV+ + GG+L L + E + +RFY E++ A++++H
Sbjct: 134 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDQEKTTTFCGTPEYLAPELLL---- 553
++RD+KP+N+LLD GHI L DFG C K+N +++ GTP+Y++PE+L
Sbjct: 194 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 253
Query: 554 GQG-YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPD---DFDKDA 607
G G Y DWW+LGV +YEML G P+Y E + + Y KI+ ++ +FP D ++A
Sbjct: 254 GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEA 313
Query: 608 KDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNF 667
KDL+ L+C +RRLG +G ++ K H FF L+W+ + + PY P V DTSNF
Sbjct: 314 KDLIQRLIC-SRERRLGQNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTSNF 370
Query: 668 D 668
D
Sbjct: 371 D 371
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 216 bits (550), Expect = 1e-55
Identities = 120/333 (36%), Positives = 196/333 (58%), Gaps = 15/333 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ +D+D++KVIG+G+FG+V VR + + K+YA+K + K ++ +S+ ER ++A
Sbjct: 87 MKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF 146
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR--SRFYTAELLCALE 494
++P++V L ++FQ LY+V+ ++ GG+L + +D+ ++FYTAE++ AL+
Sbjct: 147 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDL---VNLMSNYDVPEKWAKFYTAEVVLALD 203
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDQEKTTTFCGTPEYLAPELLL 553
A+H +I+RD+KP+N+LLD GH+ L DFG C K++ T GTP+Y++PE+L
Sbjct: 204 AIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLK 263
Query: 554 GQG----YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDK 605
QG Y + DWW++GV LYEML G P+Y + + Y KI+ ++ L FP+D K
Sbjct: 264 SQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISK 323
Query: 606 DAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTS 665
AK+L+ L D + RLG +G +EI+ HPFF W ++ P P + +D+S
Sbjct: 324 HAKNLICAFL-TDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSS 382
Query: 666 NFDQEFTREQPVDSVVNDFLSESVQQQFGGWTY 698
NFD + V++ Q F G+TY
Sbjct: 383 NFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTY 415
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 216 bits (550), Expect = 1e-55
Identities = 120/333 (36%), Positives = 196/333 (58%), Gaps = 15/333 (4%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ +D+D++KVIG+G+FG+V VR + + K+YA+K + K ++ +S+ ER ++A
Sbjct: 87 MKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF 146
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR--SRFYTAELLCALE 494
++P++V L ++FQ LY+V+ ++ GG+L + +D+ ++FYTAE++ AL+
Sbjct: 147 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDL---VNLMSNYDVPEKWAKFYTAEVVLALD 203
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDQEKTTTFCGTPEYLAPELLL 553
A+H +I+RD+KP+N+LLD GH+ L DFG C K++ T GTP+Y++PE+L
Sbjct: 204 AIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLK 263
Query: 554 GQG----YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDK 605
QG Y + DWW++GV LYEML G P+Y + + Y KI+ ++ L FP+D K
Sbjct: 264 SQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISK 323
Query: 606 DAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTS 665
AK+L+ L D + RLG +G +EI+ HPFF W ++ P P + +D+S
Sbjct: 324 HAKNLICAFL-TDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSS 382
Query: 666 NFDQEFTREQPVDSVVNDFLSESVQQQFGGWTY 698
NFD + V++ Q F G+TY
Sbjct: 383 NFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTY 415
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 216 bits (549), Expect = 1e-55
Identities = 115/328 (35%), Positives = 183/328 (55%), Gaps = 20/328 (6%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV 437
S +DF+ +K+I G++G V VR + T + +A+K I K ++ ++++ ER +L
Sbjct: 508 SEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFA 567
Query: 438 DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
+NPF+V + SF + L +V+ ++ GG+ L+ G + R Y AE + ALE LH
Sbjct: 568 ENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLH 627
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM-------------KDQEK--TTTFCG 542
++ I++RDLKP+N+L+ GHI L DFGL K+ + KD + CG
Sbjct: 628 NYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCG 687
Query: 543 TPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD 602
TPEY+APE++L QGY K VDWW +G++LYE L G P++ + +++ +++ D + +P+
Sbjct: 688 TPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEG 747
Query: 603 ---FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVM 659
DA+DL LL ++P RLG + E+K HPFF L W L + + P +
Sbjct: 748 DEALPPDAQDLTSKLLHQNPLERLGTGSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 805
Query: 660 GAMDTSNFDQEFTREQPVDSVVNDFLSE 687
DTS FD R +DS + +SE
Sbjct: 806 SEDDTSYFDTRSERYHHMDSEDEEEVSE 833
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 215 bits (548), Expect = 2e-55
Identities = 116/314 (36%), Positives = 181/314 (56%), Gaps = 34/314 (10%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F+ ++++G+G GKV VR++ TN++YALK + K ++ ++++ L E+ +LA ++PF
Sbjct: 496 FEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPF 555
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR--SRFYTAELLCALEALHDF 499
IV L SFQS + LYL + + GGE F LQ + +RFY +E+ ALE LH
Sbjct: 556 IVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLL 615
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQE----------------------KT 537
IYRDLKPENILL GHI L DF L + KD + +T
Sbjct: 616 GFIYRDLKPENILLHQSGHIMLSDFDL-SIQAKDSKVPVVKGSAQSTLVDTKICSDGFRT 674
Query: 538 TTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPL 597
+F GT EY+APE++ G G+T VDWWTLG+L+YEML G P+ ++ + + IL++ +
Sbjct: 675 NSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEV 734
Query: 598 RFP--DDFDKDAKDLLIGLLCRDPKRRLGYH-GSDEIKSHPFFNQLSWKRLKMKGYIPPY 654
FP ++ + KDL+ LL ++ +RLG G+ ++K HPFF ++ W L+ +
Sbjct: 735 SFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQ------ 788
Query: 655 KPPVMGAMDTSNFD 668
+PP++ + +D
Sbjct: 789 EPPLIPVLSEDGYD 802
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 215 bits (548), Expect = 2e-55
Identities = 116/307 (37%), Positives = 184/307 (59%), Gaps = 11/307 (3%)
Query: 357 ESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKS 416
E + G +L P + +DF K++G+GSF V+ R+ T++ YA+K + K
Sbjct: 57 EPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKR 116
Query: 417 YIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR 476
+I+ +++V + ER V++R+D+PF V L F+FQ EKLY L++ GEL ++++ G
Sbjct: 117 HIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGS 176
Query: 477 FDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKD--Q 534
FD + +RFYTAE++ ALE LH II+RDLKPENILL+ HI + DFG K+ + Q
Sbjct: 177 FDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQ 236
Query: 535 EKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ 594
+ +F GT +Y++PELL + K D W LG ++Y+++ GLPP+ + +++KI++
Sbjct: 237 ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 296
Query: 595 DPLRFPDDFDKDAKDLLIGLLCRDPKRRLG---YHGSDEIKSHPFFNQLSWKRL------ 645
FP+ F A+DL+ LL D +RLG G +K+HPFF ++W+ L
Sbjct: 297 LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPP 356
Query: 646 KMKGYIP 652
K+ Y+P
Sbjct: 357 KLTAYLP 363
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 215 bits (547), Expect = 2e-55
Identities = 123/313 (39%), Positives = 179/313 (56%), Gaps = 18/313 (5%)
Query: 376 HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA 435
HL++++F + ++IG+G FG+V RK DT K+YA+K + K I K T L ER +L+
Sbjct: 185 HLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLS 244
Query: 436 RV---DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
V D PFIV + ++F + +KL +L +NGG+L YHL + G F RFY E++
Sbjct: 245 LVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILG 304
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGL-CKLNMKDQEKTTTFCGTPEYLAPEL 551
LE +H+ ++YRDLKP NILLD GH + D GL C + K K GT Y+APE+
Sbjct: 305 LEHVHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKK---KPHASVGTHGYMAPEV 361
Query: 552 L-LGQGYTKVVDWWTLGVLLYEMLTGLPPYYD---EDVPKMYKKILQDPLRFPDDFDKDA 607
L G Y DW++LG +L+++L G P+ +D ++ + L + PD F +
Sbjct: 362 LQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPEL 421
Query: 608 KDLLIGLLCRDPKRRLGYH--GSDEIKSHPFFNQLSWKRLKMKGYIPPYKPP-----VMG 660
K LL GLL RD +RLG H GS E+K H FF + W+ + ++ Y PP PP
Sbjct: 422 KSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAAD 481
Query: 661 AMDTSNFDQEFTR 673
A D +FD+E T+
Sbjct: 482 AFDIGSFDEEDTK 494
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 214 bits (545), Expect = 4e-55
Identities = 114/294 (38%), Positives = 179/294 (60%), Gaps = 4/294 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ ++D + +G G FG+V VR +++ YALK + K++IV + +H ++ER +L +
Sbjct: 269 VELEDLQRVSTLGMGGFGRVELVRSA-SSRTYALKIMNKAHIVETKQESHVVSERRILMQ 327
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
DN +IV + +++ SEK+Y+++ GGE++ L+++GRFD +RFY A + ALE L
Sbjct: 328 CDNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYL 387
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +I+YRDLKPEN+LLD G L DFG K +K+ +T TFCGT EY+APE++L +G
Sbjct: 388 HRKNIVYRDLKPENMLLDRNGWPKLVDFGFAK-KLKNGGRTWTFCGTAEYVAPEIVLNKG 446
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ--DPLRFPDDFDKDAKDLLIGL 614
+ VD W LG+ + E+LTG PP+ D Y IL+ + +P K+A D+++ L
Sbjct: 447 HDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAIDMMLSL 506
Query: 615 LCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
+P RLG+ EI+ H +F+ + + PP+ P V +DTSNFD
Sbjct: 507 CKYEPTERLGFGDIGEIRHHIWFDNFDFVGFRAHRIRPPFIPSVANDIDTSNFD 560
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 214 bits (544), Expect = 5e-55
Identities = 113/295 (38%), Positives = 172/295 (58%), Gaps = 14/295 (4%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
++ + DF+L K+ G GS+ KV++ +K+D +YALK + K +I +++ + ER VL
Sbjct: 35 ENFTYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVL 94
Query: 435 ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
++++P IV L F+FQ ++ LY+ L GGELF + R+GR +RFY+AE++ ALE
Sbjct: 95 DQLEHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALE 154
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK----------LNMKDQEKTTTFCGTP 544
+H+ +I+RD+KPEN+LL GHI + DFG K N +K TF GT
Sbjct: 155 YIHNMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTA 214
Query: 545 EYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFD 604
Y+ PE+L T D W LG LY+ML+G P+ D ++++I+ ++FP+ F
Sbjct: 215 AYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFS 274
Query: 605 KDAKDLLIGLLCRDPKRR--LGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPP 657
+ A+DL+ LL DP RR G G D +K HPFF + WK L+ + PP P
Sbjct: 275 EAARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWKNLRSQ--TPPKLAP 327
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 212 bits (540), Expect = 1e-54
Identities = 120/306 (39%), Positives = 176/306 (57%), Gaps = 17/306 (5%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
L DDF++LKVIG+G+F +V V+ + T ++YA+K + K ++ + EV+ ER VL
Sbjct: 66 LQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN 125
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREG-RFDLSRSRFYTAELLCALEA 495
D +I L F+FQ LYLV+ + GG+L L + G R +RFY AE++ A+++
Sbjct: 126 GDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDS 185
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDQEKTTTFCGTPEYLAPELLLG 554
+H ++RD+KP+NILLD GHI L DFG C KL ++ GTP+YL+PE+L
Sbjct: 186 VHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQA 245
Query: 555 QG-------YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFP---DD 602
G Y DWW LGV YEM G P+Y + + Y KI+ ++ L P +
Sbjct: 246 VGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEG 305
Query: 603 FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
++A+D + LLC P+ RLG G+ + ++HPFF L W L + +PP+ P GA
Sbjct: 306 VPEEARDFIQRLLC-PPETRLGRGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFEGAT 362
Query: 663 DTSNFD 668
DT NFD
Sbjct: 363 DTCNFD 368
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 211 bits (538), Expect = 2e-54
Identities = 119/337 (35%), Positives = 197/337 (58%), Gaps = 20/337 (5%)
Query: 337 NLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKV 396
N K+ A ++ + I+L+ K+ + + S ++ + +++ +G G FG+V
Sbjct: 423 NWKLSKALSLEM-----IQLKEKVARFSSSSPFQ----------NLEIIATLGVGGFGRV 467
Query: 397 MQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLY 456
V+ ++ N +A+K IRK +IV + H +E+ +L + +PFIV L +F+ ++ +Y
Sbjct: 468 ELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVY 527
Query: 457 LVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQ 516
++L GGEL+ L+ G FD S+F A + A + LH IIYRDLKPEN++LD +
Sbjct: 528 MLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAE 587
Query: 517 GHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTG 576
G++ L DFG K + +KT TFCGTPEY+APE++L +G+ VD+W+LG+L+YE+LTG
Sbjct: 588 GYLKLVDFGFAK-KIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTG 646
Query: 577 LPPYYDEDVPKMYKKILQ--DPLRFPDDFDKDAKDLLIGLLCRDPKRRLG--YHGSDEIK 632
PP+ D Y IL+ + + FP + +DL+ L ++P RLG +G ++IK
Sbjct: 647 NPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIK 706
Query: 633 SHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
H + N +W+ LK + P + + G +D S FD+
Sbjct: 707 KHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDK 743
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 211 bits (538), Expect = 2e-54
Identities = 113/314 (35%), Positives = 182/314 (56%), Gaps = 22/314 (7%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
+DFD++K+I G++G V V+ + T + +A+K I K+ ++ +++V AER +L+ DN
Sbjct: 833 NDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADN 892
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
PF+V + SF++ + L LV+ ++ GG+ L+ G +RFY AE + A+E LH +
Sbjct: 893 PFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSY 952
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKD----------QEKTTTFC-----GTP 544
I++RDLKP+N+L+ GHI L DFGL K+ + +T F GTP
Sbjct: 953 GIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTP 1012
Query: 545 EYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFD 604
EY+APE++L QGY K VDWW++G++LYE L G P++ E +++ + D + +PD D
Sbjct: 1013 EYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSED 1072
Query: 605 ----KDAKDLLIGLLCRDPKRRLG-YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVM 659
+AKD++ LL ++P+ RLG G+ E+K H +F + W L + + P +
Sbjct: 1073 WPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQK--AEFVPQLS 1130
Query: 660 GAMDTSNFDQEFTR 673
DTS FD R
Sbjct: 1131 HDDDTSYFDTRMDR 1144
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 211 bits (537), Expect = 3e-54
Identities = 107/306 (34%), Positives = 178/306 (57%), Gaps = 20/306 (6%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DF+ +K+I G++G V VR +++ + +A+K I K ++ ++++ ER +L +NP
Sbjct: 38 DFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 97
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
F+V + SF++ L +V+ ++ GG+ ++ G + +R Y AE + ALE LH++
Sbjct: 98 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 157
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCKLNM-------------KDQEK--TTTFCGTPE 545
I++RDLKP+N+L+ GHI L DFGL K+ + KD + CGTPE
Sbjct: 158 IVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPE 217
Query: 546 YLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFD- 604
Y+APE++L QGY K VDWW +G++LYE L G P++ + +++ +++ D + +P+ +
Sbjct: 218 YIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEA 277
Query: 605 --KDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAM 662
DA+DL+ LL ++P RLG G+ E+K H FF L W L + + P +
Sbjct: 278 PPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQK--AEFIPQLESED 335
Query: 663 DTSNFD 668
DTS FD
Sbjct: 336 DTSYFD 341
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 211 bits (537), Expect = 3e-54
Identities = 116/350 (33%), Positives = 200/350 (57%), Gaps = 17/350 (4%)
Query: 369 YKPSTHK----HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEV 424
YKP + ++++DF +K+IG G+FG+V VR + ++++YA+K + K ++ + +
Sbjct: 70 YKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDS 129
Query: 425 THTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR--S 482
ER ++A ++ +IV L F+FQ ++ LY+V+ F+ GG++ + G +D+ +
Sbjct: 130 AFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDI---VSLMGDYDIPEKWA 186
Query: 483 RFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDQEKTTTFC 541
FYT E++ AL+ +H+ ++RD+KP+N+LLD GH+ L DFG C ++ Q ++
Sbjct: 187 IFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAV 246
Query: 542 GTPEYLAPELLLGQG----YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QD 595
GTP+Y++PE+L QG Y + DWW++G+ LYEML G P+Y + + Y KI+ ++
Sbjct: 247 GTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKN 306
Query: 596 PLRFPDDFD-KDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPY 654
L FP + + + LI D +RLG +G ++IK+HPFF +W ++ +PP
Sbjct: 307 SLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPV 366
Query: 655 KPPVMGAMDTSNFDQEFTREQPVDSVVNDFLSESVQQQFGGWTYVGSEQL 704
P + DT NF+ E+P + + F G+TY G QL
Sbjct: 367 VPELSSDDDTRNFEDIERDEKPEEVFPVPKGFDGNHLPFIGFTYTGDYQL 416
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 210 bits (535), Expect = 5e-54
Identities = 120/338 (35%), Positives = 182/338 (53%), Gaps = 53/338 (15%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F +K +G G+FG+V K DT+ +YA+K +RK ++++++V H AER +LA DN +
Sbjct: 668 FVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERDILAEADNEW 727
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
+V L +SFQ + LY V+ +I GG++ L R F +RFY AEL A+E++H
Sbjct: 728 VVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGF 787
Query: 502 IYRDLKPENILLDYQGHIALCDFGLC---------------------------------K 528
I+RD+KP+NIL+D GHI L DFGLC
Sbjct: 788 IHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSN 847
Query: 529 LNMKDQEKTT--------------TFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEML 574
D+ KT + GTP Y+APE+LL +GYT++ DWW++GV+L+EML
Sbjct: 848 CRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEML 907
Query: 575 TGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLLIGLLCRDPKRRLGYHGSDE 630
G PP+ + K++ ++ L P +A+DL+ L C RLG +G+D+
Sbjct: 908 VGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCC-SADHRLGRNGADD 966
Query: 631 IKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
+K+HPFF+ + + ++ PY P + MDTSNFD
Sbjct: 967 LKAHPFFSAIDFSS-DIRKQPAPYVPTISHPMDTSNFD 1003
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 209 bits (533), Expect = 9e-54
Identities = 115/308 (37%), Positives = 176/308 (56%), Gaps = 15/308 (4%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DF+ K+ G GS+ KV++ +K++T +YALK + K +I +++ + ER VL ++++P
Sbjct: 40 DFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHP 99
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
I+ L F+FQ + LY+ L GGELF + R+GR +RFYTAE++ ALE +H
Sbjct: 100 GIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHSMG 159
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCK----------LNMKDQEKTTTFCGTPEYLAPE 550
+I+RD+KPEN+LL GHI + DFG K N +K TF GT Y+ PE
Sbjct: 160 LIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVPPE 219
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
+L T D W LG LY+ML+G P+ D ++++I+ ++FP+ F + A+DL
Sbjct: 220 VLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEAARDL 279
Query: 611 LIGLLCRDPKRR--LGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
+ LL +P RR G G +K HPFFN + WK L+ + PP P A T++ +
Sbjct: 280 IDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKNLRSQ--TPPKLAP-DPASQTASPE 336
Query: 669 QEFTREQP 676
++ T P
Sbjct: 337 RDDTHGSP 344
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 209 bits (532), Expect = 1e-53
Identities = 123/311 (39%), Positives = 176/311 (56%), Gaps = 20/311 (6%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
L+++DF + ++IG+G FG+V RK DT K+YA+K + K I K T L ER +L+
Sbjct: 186 LTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSL 245
Query: 437 V----DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
V D PFIV + ++FQS +KL +L +NGG+L YHL + G F FY +E++
Sbjct: 246 VSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILG 305
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGL-CKLNMKDQEKTTTFCGTPEYLAPEL 551
LE +H+ ++YRDLKP NILLD GH+ + D GL C + K K GT Y+APE+
Sbjct: 306 LEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKK---KPHASVGTHGYMAPEV 362
Query: 552 LL-GQGYTKVVDWWTLGVLLYEMLTGLPPY---YDEDVPKMYKKILQDPLRFPDD-FDKD 606
L G Y DW++LG +LY++L G P+ +D ++ K L + P++ KD
Sbjct: 363 LAKGVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNEGLSKD 422
Query: 607 AKDLLIGLLCRDPKRRLGYHGS--DEIKSHPFFNQLSWKRLKMKGYIPPYKPP-----VM 659
+DLL GLL RD RLG G E+K HPFF + W+ + ++ PP PP
Sbjct: 423 CRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAA 482
Query: 660 GAMDTSNFDQE 670
A D NFD +
Sbjct: 483 DAFDIGNFDDD 493
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 209 bits (531), Expect = 2e-53
Identities = 123/352 (34%), Positives = 184/352 (51%), Gaps = 54/352 (15%)
Query: 369 YKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTL 428
Y + +S F ++ IG G+FGKV VRK DT K+YA+K++ K+ ++ K + H
Sbjct: 489 YTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVK 548
Query: 429 AERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAE 488
AER +LA D+P+IV L FSFQ LY ++ ++ GG++ L ++G F+ +RFY AE
Sbjct: 549 AERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAE 608
Query: 489 LLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK-------------------- 528
L CA+E +H+ I+RDLKP+NIL+D GHI L DFGLC
Sbjct: 609 LACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRV 668
Query: 529 ------------------LNMKDQEKTTT---FCGTPEYLAPELLLGQGYTKVVDWWTLG 567
LN++ Q + T GT Y+APE++ G+ + DWW+ G
Sbjct: 669 DSFSLPPEVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTG 728
Query: 568 VLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPD-----DFDKDAKDLLIGLLCRDPKRR 622
V+LYEM+ G P++D D P + +++ F D + K+ ++ L+C D R
Sbjct: 729 VILYEMVFGRVPFHD-DTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLIC-DASSR 786
Query: 623 LGYHGSD------EIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
LG HG D ++K+HP+F + W L+ Y P V DTSNF+
Sbjct: 787 LGSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHDEDTSNFE 838
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 209 bits (531), Expect = 2e-53
Identities = 115/304 (37%), Positives = 180/304 (58%), Gaps = 11/304 (3%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DF LKVIG+G+FG+V VR TN +YA+K + K ++ +++ ER ++A ++
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSE 126
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
+IV L+++FQ LY+V+ ++ GG+L +L +RFYTAE++ AL ALH
Sbjct: 127 WIVRLQYAFQDPRHLYMVMEYMPGGDL-VNLMTSYEVSEKWTRFYTAEIVEALAALHSMG 185
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDQEKTTTFCGTPEYLAPELLLGQG--- 556
I+RD+KP+N+L+ GHI L DFG C K+N + +T GTP+Y++PE+L QG
Sbjct: 186 YIHRDVKPDNMLISISGHIKLADFGTCVKMNANGVVRCSTAVGTPDYISPEVLRNQGQDA 245
Query: 557 -YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD--FDKDAKDLL 611
+ K VDWW++GV +YEML G P+Y E + Y I+ + L+FPD+ AKD++
Sbjct: 246 EFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQAKDII 305
Query: 612 IGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEF 671
L P RLG + D+I++H FF W ++ PP P + DT++F++
Sbjct: 306 KKFLSAAPD-RLGRNSVDDIRNHKFFVNDEWTFATLREASPPVIPSLKSDDDTTHFEEIE 364
Query: 672 TREQ 675
TR++
Sbjct: 365 TRDR 368
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 208 bits (529), Expect = 3e-53
Identities = 103/281 (36%), Positives = 170/281 (59%), Gaps = 10/281 (3%)
Query: 386 KVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPL 445
+V+GKG FG+V + + T K+YA K + K + + + E+ +L +V + FIV L
Sbjct: 194 RVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKVHSRFIVSL 253
Query: 446 KFSFQSSEKLYLVLAFINGGELFYHL----QREGRFDLSRSRFYTAELLCALEALHDFDI 501
++F++ L LV+ +NGG++ YH+ + F R+ FYTA+++C LE LH I
Sbjct: 254 AYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIICGLEHLHQRRI 313
Query: 502 IYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVV 561
+YRDLKPEN+LLD G++ + D GL + Q KT + GTP ++APELL G+ Y V
Sbjct: 314 VYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMAPELLQGEEYDFSV 373
Query: 562 DWWTLGVLLYEMLTGLPPYYDE----DVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
D++ LGV LYEM+ P+ + ++ +I+ +P+++PD F + +KD LL +
Sbjct: 374 DYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFSQASKDFCEALLEK 433
Query: 618 DPKRRLGYHGS--DEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
DP++RLG+ D++++HP F L+W++L+ +PP+ P
Sbjct: 434 DPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIP 474
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 208 bits (529), Expect = 3e-53
Identities = 108/314 (34%), Positives = 178/314 (56%), Gaps = 22/314 (7%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
DDFD ++++ G++G V VR R+T + +ALK + K ++ +++V AER +L DN
Sbjct: 356 DDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADN 415
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
PF+V SF++ + L +++ ++ GG+ L+ G + R Y AE + A+E LH +
Sbjct: 416 PFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSY 475
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKD----------------QEKTTTFCGT 543
I++RDLKP+N+L+ GHI L DFGL K+ + + Q + CGT
Sbjct: 476 GIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGT 535
Query: 544 PEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD- 602
PEY+APE++L +GY K VDWW LG++LYE L G+ P++ E ++ K++ + + +P++
Sbjct: 536 PEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEED 595
Query: 603 --FDKDAKDLLIGLLCRDPKRRLG-YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVM 659
+A DL LL ++P RLG +G+ ++ +H FF L + L + + P +
Sbjct: 596 EALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTSLLRQK--AEFVPQLD 653
Query: 660 GAMDTSNFDQEFTR 673
DTS FD R
Sbjct: 654 NEEDTSYFDTRTDR 667
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 207 bits (528), Expect = 3e-53
Identities = 97/230 (42%), Positives = 149/230 (64%), Gaps = 3/230 (1%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ D D L +G G+FG+V V+++ +ALK + ++ + + H E++VL V
Sbjct: 46 LQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVS 105
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+PF++ L +++ LY+++ ++ GGELF +L+ G F + FY+AE++CA+E LH
Sbjct: 106 HPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHS 165
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+I+YRDLKPENILLD GHI L DFG K K ++T T CGTPEYLAPE++ +G+
Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAK---KLVDRTWTLCGTPEYLAPEVIQSKGHG 222
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
+ VDWW LG+L++EML+G PP++D++ +Y+KIL L FP D K
Sbjct: 223 RAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHLDFHVK 272
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 207 bits (528), Expect = 3e-53
Identities = 140/423 (33%), Positives = 218/423 (51%), Gaps = 38/423 (8%)
Query: 273 ISTFDVTRRLPFLKIDVFARIPSILLPSQNWQETQISNNDILGDYVKKIRNNSDIHLDSF 332
I+T +RL FLK I S Q W G+ + + + D LD+F
Sbjct: 11 ITTGSCKKRLTFLKC-----ILSDTTSDQKWAAE-------FGEDTEGHQFSLDYLLDTF 58
Query: 333 HLPLNLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGS 392
+ D SN L + K+ K + + K LS DDFD+LK+IG+G+
Sbjct: 59 IV----LYDECSNSSLRREKGVSDFLKLSKPFVHIVRK----LRLSRDDFDILKIIGRGA 110
Query: 393 FGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSS 452
FG+V V+ T K+YA+K + K ++ ++E ER VL D +I L ++FQ +
Sbjct: 111 FGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWITNLHYAFQDN 170
Query: 453 EKLYLVLAFINGGELFYHLQR-EGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENI 511
LYLV+ + GG+L L + E + ++FY E++ A+ ++H ++RD+KP+N+
Sbjct: 171 INLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNV 230
Query: 512 LLDYQGHIALCDFGLC-KLNMKDQEKTTTFCGTPEYLAPELLL----GQG-YTKVVDWWT 565
LLD +GH+ L DFG C +L+ ++ GTP+Y++PE+L G+G Y DWW+
Sbjct: 231 LLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWWS 290
Query: 566 LGVLLYEMLTGLPPYYDEDVPKMYKKIL--QDPLRFPDD------FDKDAKDLLIGLLCR 617
LGV +YEML G P+Y E + + Y KI+ Q+ P + ++DLL L+C
Sbjct: 291 LGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLIC- 349
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPV 677
P+ RLG +G + HP+F + WK ++ PY P V DTSNFD + +
Sbjct: 350 IPENRLGQNGIQDFMDHPWFVGIDWKNIRQGP--APYVPEVSSPTDTSNFDVDDNDVRLT 407
Query: 678 DSV 680
DS+
Sbjct: 408 DSI 410
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 206 bits (525), Expect = 8e-53
Identities = 101/248 (40%), Positives = 154/248 (61%), Gaps = 5/248 (2%)
Query: 423 EVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRS 482
+ H E+ VL ++ +PFIV + S + S LY+++ F+ GGE+F +L+ F S +
Sbjct: 3 QTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMA 62
Query: 483 RFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCG 542
RFY +E++CALE +H I+YRDLKPEN++L +GHI + DFG K + +++T T CG
Sbjct: 63 RFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK---ELRDRTYTICG 119
Query: 543 TPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD 602
TP+YLAPE L G+ K VDWW LG+L+YEM+ G PP+ + ++Y I++ L+FP
Sbjct: 120 TPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRS 179
Query: 603 FDKDAKDLLIGLLCRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMG 660
F+ AKDL+ LL D +R+G +G+ ++K H +F +++W PP P +
Sbjct: 180 FNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYH 239
Query: 661 AMDTSNFD 668
DT NFD
Sbjct: 240 PGDTGNFD 247
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 206 bits (525), Expect = 8e-53
Identities = 123/335 (36%), Positives = 182/335 (53%), Gaps = 52/335 (15%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDT-NKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
F LK IG G+FG+V V K DT N +YA+K +RK+ ++ +++V H AER +LA DN
Sbjct: 719 FVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNN 778
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
++V L +SFQ + LY V+ +I GG+L L + G F+ +RFY AE+ CA++++H
Sbjct: 779 WVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMG 838
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLC--------------------------------- 527
I+RD+KP+NIL+D GHI L DFGLC
Sbjct: 839 FIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSEN 898
Query: 528 --------KLNMKDQEKTT--TFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGL 577
+ M+D ++ + GTP Y+APE+L GYT++ D+W++GV+LYEML G
Sbjct: 899 GPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQ 958
Query: 578 PPYYDEDVPKMYKKIL--QDPLRFPD--DFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKS 633
PP+ + +K++ + L P + ++A D LI LC +RLG DE+KS
Sbjct: 959 PPFLANSPLETQQKVINWEKTLHIPPQAELSREATD-LIRRLCASADKRLG-KSVDEVKS 1016
Query: 634 HPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
H FF + + M+ PY P + DTSNFD
Sbjct: 1017 HDFFKGIDF--ADMRKQKAPYIPEIKHPTDTSNFD 1049
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 204 bits (519), Expect = 4e-52
Identities = 114/304 (37%), Positives = 174/304 (56%), Gaps = 15/304 (4%)
Query: 364 NLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSE 423
N + +K + ++ + F +V+GKG FG+V + R T K+YA K + K I +
Sbjct: 168 NRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKG 227
Query: 424 VTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR--FDLSR 481
L E+ +L +V++ F+V L +++++ + L LVL +NGG+L +H+ G+ F +R
Sbjct: 228 EAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEAR 287
Query: 482 SRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFC 541
+ FY AE+ C LE LH I+YRDLKPENILLD GHI + D GL +++ + +
Sbjct: 288 AVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLA-VHVPEGQTIKGRV 346
Query: 542 GTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYD-------EDVPKMYKKILQ 594
GT Y+APE++ + YT DWW LG LLYEM+ G P+ E+V ++ K++
Sbjct: 347 GTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEV-- 404
Query: 595 DPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYIP 652
P + + F A+ L LLC+DP RLG G E+K HP F +L++KRL P
Sbjct: 405 -PEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEP 463
Query: 653 PYKP 656
P+KP
Sbjct: 464 PFKP 467
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 204 bits (518), Expect = 5e-52
Identities = 114/300 (38%), Positives = 174/300 (58%), Gaps = 9/300 (3%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRK--RDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
L + D +++ +G G FG+V V+ +D I+ALK ++K +IV + H +ER ++
Sbjct: 452 LKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIM 511
Query: 435 ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
+PFI L +F+ + +Y++L GGE++ L+ G F+ + ++F +L A E
Sbjct: 512 LSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFE 571
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
LH IIYRDLKPEN++LD +G++ + DFG K + KT TFCGTPEY+APE++L
Sbjct: 572 YLHARGIIYRDLKPENLMLDERGYVKIVDFGFAK-QIGTSSKTWTFCGTPEYVAPEIILN 630
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ--DPLRFPDDFDKDAKDLLI 612
+G+ + VD+W LG+L++E+L G PP+ D + Y IL+ D + FP + A LI
Sbjct: 631 KGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQ-LI 689
Query: 613 GLLCRD-PKRRLGYH--GSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQ 669
LCRD P RLGY G +IK H +F W L + IPP+ P+ D FD+
Sbjct: 690 KRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDR 749
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 203 bits (517), Expect = 7e-52
Identities = 123/360 (34%), Positives = 182/360 (50%), Gaps = 65/360 (18%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVT------------ 425
++ DF ++V+G+G++GKV+ V+ +T+K+YA+K +RK+ I+ T
Sbjct: 124 NLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDG 183
Query: 426 --------------HTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHL 471
T AER++L+ +++P IV L +SF + KLYL+L +I GGELFYHL
Sbjct: 184 NNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHL 243
Query: 472 QREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNM 531
+ G D + FY AE+ CAL LH ++YRDLKPEN LL+ +GH+ L DFGL K +
Sbjct: 244 KEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSA 303
Query: 532 KDQ----------EKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYY 581
D + GTPEY APE+LLG+ Y++ DW++LG LLY+ML G PPY
Sbjct: 304 NDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYT 363
Query: 582 DEDVPKMYKKILQDPL--RFPDDFDKDAKDLLIGLL-----------------------C 616
+ + KI Q+ + P + KD+L LL
Sbjct: 364 GSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNKPT 423
Query: 617 RDPKRRLGYHGSDEIKSHPFFNQLSWKRLK----MKGYIPPYKPPVMGAMDTSNFDQEFT 672
+ K++ G + H F ++ WK L+ K + P P + NFD EFT
Sbjct: 424 KSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVITDLELAENFDTEFT 483
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 202 bits (515), Expect = 1e-51
Identities = 111/282 (39%), Positives = 162/282 (57%), Gaps = 5/282 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVR-KRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA 435
L I DF+ +KV+G G+FGKV VR K ++A+K + I+ + E ++L
Sbjct: 2 LKIQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILK 61
Query: 436 RVDN-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
R+ PF+ L + K+ L++ ++ GGELFY L++ GRFD +RFY AE++ AL
Sbjct: 62 RIYGCPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALR 121
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
+H I+YRDLKPENIL+ GHI L DFG ++ + E GTPEY++PE L
Sbjct: 122 FIHGRGILYRDLKPENILITSTGHIKLIDFGF---SVYESENIYMISGTPEYMSPEKLRS 178
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGL 614
+ + D+W LGV++YEML G PP+YD +Y KIL+ + FP A+ L+ GL
Sbjct: 179 EDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVARCLITGL 238
Query: 615 LCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
L ++ RLG G EI HPFF + W ++ + PP+ P
Sbjct: 239 LDKNRATRLGTKGICEIMGHPFFKGIDWHEVESRRIEPPFIP 280
>CE01554 [T] KOG0986 G protein-coupled receptor kinase
Length = 642
Score = 201 bits (510), Expect = 4e-51
Identities = 111/297 (37%), Positives = 175/297 (58%), Gaps = 23/297 (7%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F L +V+GKG FG+V + R + K+YALK + K + + T +L E+ +L R+++PF
Sbjct: 203 FRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQRINSPF 262
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQR--EGRFDLSRSRFYTAELLCALEALHDF 499
+V L +++++ + L LVL +NGG+L +HL G FD R +FY AE+ L+ LH
Sbjct: 263 VVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDEKRVQFYAAEITLGLQHLHSE 322
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTK 559
I+YRDLKPENILLD GH+ + D GL + +KD E GT Y+APE++ + Y+
Sbjct: 323 RILYRDLKPENILLDDFGHVRISDLGLA-VEIKDNEPIKGRVGTVGYMAPEIVKNERYSY 381
Query: 560 VVDWWTLGVLLYEMLTGLPPYYD--EDVPK--MYKKILQDPLRFPDDFDKDAKDLLIGLL 615
VDWW +G L+YEM+ G P+ E V + + +++ +D ++ + F + A+ L GLL
Sbjct: 382 GVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQEKYSEKFSEAARTLCRGLL 441
Query: 616 CRDPKRRLGYH-------GSDEIKSHPFFN---------QLSWKRLKMKGYIPPYKP 656
++P RLG G++EI++HPFFN + WK+++ PP+ P
Sbjct: 442 HKEPGFRLGCRRVGRPEDGAEEIRAHPFFNTADTVTGREPVPWKKMEAGKVTPPFCP 498
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 197 bits (500), Expect = 6e-50
Identities = 109/303 (35%), Positives = 178/303 (57%), Gaps = 19/303 (6%)
Query: 367 VDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTH 426
++ +P T+K F + +V+GKG FG+V + R T K+YA K + K I + +
Sbjct: 299 LEAQPITYK-----TFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESM 353
Query: 427 TLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREG---RFDLSRSR 483
L E+ +L ++++PF+V L +++++ + L LVL +NGG+L +H+ G F+L R+R
Sbjct: 354 VLIEKQILQKINSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERAR 413
Query: 484 FYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGT 543
FY AE+ C L+ LH I+YRD KPENILLD GH+ + D GL + + + E GT
Sbjct: 414 FYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISDLGLA-VEIPEGEMVRGRVGT 472
Query: 544 PEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPY--YDEDVPK--MYKKILQDPLRF 599
Y+APE++ + Y DW++ G LLYEM+ G P+ E V + + +++ +DP ++
Sbjct: 473 VGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDPEKY 532
Query: 600 PDDFDKDAKDLLIGLLCRDPKRRLGYH----GSDEIKSHPFFN--QLSWKRLKMKGYIPP 653
F+ +AK + LL + K+RLG G ++ +HPFF+ QL+W+RL+ PP
Sbjct: 533 SSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEAGMLEPP 592
Query: 654 YKP 656
+ P
Sbjct: 593 FVP 595
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 196 bits (497), Expect = 1e-49
Identities = 113/290 (38%), Positives = 162/290 (54%), Gaps = 7/290 (2%)
Query: 385 LKVIGKGSFGKVMQVRKR-DTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIV 443
L +G G FG+V V D K +ALKA++K +IV + H AER ++ +IV
Sbjct: 429 LATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIV 488
Query: 444 PLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIY 503
L +F+ + +Y++L GGEL+ L+ G FD +RFY A +L LE LH +I+Y
Sbjct: 489 KLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVY 548
Query: 504 RDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDW 563
RDLKPEN LL G++ L DFG K + KT TFCGTPEY++PE++L +G+ + D+
Sbjct: 549 RDLKPENCLLANTGYLKLVDFGFAK-KLASGRKTWTFCGTPEYVSPEIILNKGHDQAADY 607
Query: 564 WTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ--DPLRFPDDFDKDAKDLLIGLLCRD-PK 620
W LG+ + E++ G PP+ D K Y IL+ D L P+ L+ LCRD P
Sbjct: 608 WALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPG 667
Query: 621 RRL--GYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
RL G G ++I+ H +F W+ L+ + PP P V D +NFD
Sbjct: 668 ERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFD 717
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 196 bits (497), Expect = 1e-49
Identities = 113/290 (38%), Positives = 162/290 (54%), Gaps = 7/290 (2%)
Query: 385 LKVIGKGSFGKVMQVRKR-DTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIV 443
L +G G FG+V V D K +ALKA++K +IV + H AER ++ +IV
Sbjct: 472 LATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIV 531
Query: 444 PLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIY 503
L +F+ + +Y++L GGEL+ L+ G FD +RFY A +L LE LH +I+Y
Sbjct: 532 KLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVY 591
Query: 504 RDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDW 563
RDLKPEN LL G++ L DFG K + KT TFCGTPEY++PE++L +G+ + D+
Sbjct: 592 RDLKPENCLLANTGYLKLVDFGFAK-KLASGRKTWTFCGTPEYVSPEIILNKGHDQAADY 650
Query: 564 WTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ--DPLRFPDDFDKDAKDLLIGLLCRD-PK 620
W LG+ + E++ G PP+ D K Y IL+ D L P+ L+ LCRD P
Sbjct: 651 WALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPG 710
Query: 621 RRL--GYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD 668
RL G G ++I+ H +F W+ L+ + PP P V D +NFD
Sbjct: 711 ERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFD 760
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 196 bits (497), Expect = 1e-49
Identities = 127/368 (34%), Positives = 204/368 (54%), Gaps = 40/368 (10%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
++ DDF + +IG+G FG V V +R TN IYA+K I+KS +V+ S+V ER +++
Sbjct: 108 VNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKS-VVTTSQVKE---ERDIMSI 163
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
++ +++ L+++FQ ++ LYLV+ ++ GG+L + R G FD +RFY AEL AL L
Sbjct: 164 RNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTL 223
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFG-LCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
H+ ++RD+KPENIL+D GHI L DFG L+ + + GTP+Y+APELL
Sbjct: 224 HEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTI 283
Query: 556 GYTKV--------VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKI--------LQDPLRF 599
K+ D+W++G++ YE++ P+++++V + Y KI L++ + F
Sbjct: 284 STYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISF 343
Query: 600 PDDFDKDAK-DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV 658
P D LI L +P +RL Y + IK+HPFF+++ W ++ + +PP P V
Sbjct: 344 PADLKVSVNYRNLIESLVTNPSKRLSY---ERIKNHPFFSEIPWGSIRSQ--VPPIIPTV 398
Query: 659 MGAMDTSNFD----QEFTREQPV-------DSVVNDFLSESVQQQFGGWTYVGSEQLGQS 707
DTSNF+ + REQ V + NDF + + F G+++V E+ S
Sbjct: 399 RSDDDTSNFEDGIRHKTRREQGVAKKSLTTNMKSNDFSGKDL--PFIGYSFVHMEKSAIS 456
Query: 708 MLPDRSFQ 715
D Q
Sbjct: 457 ATTDEKLQ 464
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 195 bits (495), Expect = 2e-49
Identities = 113/348 (32%), Positives = 187/348 (53%), Gaps = 54/348 (15%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
FDLL +G+G +G V +KR+T+++ A+K ++KS + +EV H L ER +L ++ +
Sbjct: 162 FDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEW 221
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
+V L ++FQ EK+YL + ++ GG+ L +G +++RFY AE++ A+ A+H
Sbjct: 222 LVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLGY 281
Query: 502 IYRDLKPENILLDYQGHIALCDFGLC---------------------------------- 527
++RDLKPEN L+D +GHI L DFGL
Sbjct: 282 MHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSAVNPQRPYLTQKQRRN 341
Query: 528 ---KLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDED 584
L K++ K + G+PEY+APE++ G+ Y + VD+W+LG + YE L G PP+
Sbjct: 342 IYKALLEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGST 401
Query: 585 VPK------MYKKILQDPLRFPDD-FDKDAKDL------LIGLLCRDPKRRLGYHGSDEI 631
+ + ++++LQ P + + +DK A+ + I +P R + + EI
Sbjct: 402 LQETWTNLYYWREMLQRPSKNENGIYDKKARSVSDEAWSFITKCLTEPTSR--FQSTIEI 459
Query: 632 KSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDS 679
+ HPFF +L W L+ K +PP+ P + +DTS FD +F EQ +D+
Sbjct: 460 QKHPFFKRLHWNGLR-KRAVPPFVPRLENQLDTSYFD-DFNDEQVLDA 505
>Hs21166359 [T] KOG0986 G protein-coupled receptor kinase
Length = 553
Score = 194 bits (492), Expect = 5e-49
Identities = 113/298 (37%), Positives = 178/298 (58%), Gaps = 12/298 (4%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F +V+GKG FG+V V+ ++T K+YA K + K + K L E+ +L +V +PF
Sbjct: 191 FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSPF 250
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR--FDLSRSRFYTAELLCALEALHDF 499
IV L ++F+S L LV++ +NGG+L +H+ G D+SR FY+A++ C + LH+
Sbjct: 251 IVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGMLHLHEL 310
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ-GYT 558
I+YRD+KPEN+LLD G+ L D GL + MK + T GT Y+APE+L+ + Y+
Sbjct: 311 GIVYRDMKPENVLLDDLGNCRLSDLGLA-VEMKGGKPITQRAGTNGYMAPEILMEKVSYS 369
Query: 559 KVVDWWTLGVLLYEMLTGLPPY--YDEDVPK--MYKKILQDPLRFP-DDFDKDAKDLLIG 613
VDW+ +G +YEM+ G P+ Y E V K + ++ LQD ++F D+F ++AKD+
Sbjct: 370 YPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRL 429
Query: 614 LLCRDPKRRLG-YHGSDEIKSHPFFNQLSWKRLKMKGYIPPY--KPPVMGAMDTSNFD 668
L + P++RLG SD+ + H FF +++ RL+ PP+ P V+ A D + D
Sbjct: 430 FLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYAKDIAEID 487
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 193 bits (490), Expect = 9e-49
Identities = 116/300 (38%), Positives = 164/300 (54%), Gaps = 35/300 (11%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F+ + ++GKG G+V VR++ + K YA+K + K ++ +++ AE+ +LA ++PF
Sbjct: 195 FEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPF 254
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQRE-GR-FDLSRSRFYTAELLCALEALHDF 499
IV L SFQS E LYL + + GGE F LQR GR + ++FY AE+ ALE LH
Sbjct: 255 IVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLM 314
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCK------------------------LNMKD-- 533
IYRDLKPENILL GHI L DF L K L+ K
Sbjct: 315 GFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCI 374
Query: 534 -QEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKI 592
+T +F GT EY+APE++ G G+T VDWWTLG+L YEML P+ ++ + I
Sbjct: 375 ADFRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNI 434
Query: 593 LQDPLRFPDDFDKDA-----KDLLIGLLCRDPKRRLGYH-GSDEIKSHPFFNQLSWKRLK 646
L + FP+ D + K+L+ LL +D RLG G+ ++K HPFF + W L+
Sbjct: 435 LHKDVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFKNVQWALLR 494
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 192 bits (489), Expect = 1e-48
Identities = 121/349 (34%), Positives = 180/349 (50%), Gaps = 36/349 (10%)
Query: 358 SKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSY 417
++ GK S + + ++ F+ ++++G+G GKV VR++ ++++A+K + K
Sbjct: 131 TEYGKRTYSGNSTKISRVEVTPHSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKRE 190
Query: 418 IVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRF 477
++ + +V LAE+ +L + +PFIV L SFQS + LYL + + GGE F L +
Sbjct: 191 MIKRHKVNRVLAEQEILTKSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKH 250
Query: 478 DLSRSR--FYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKL------ 529
L FY AE+ ALE LH IYRDLKPENILL GHI L DF L K
Sbjct: 251 ILPEKDACFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTH 310
Query: 530 --------NMKDQEK-------------TTTFCGTPEYLAPELLLGQGYTKVVDWWTLGV 568
+ QEK T +F GT EY+APE++ G+T VDWWTLG+
Sbjct: 311 PTVVLPKHSTFSQEKPALDTNSYFSNFRTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGI 370
Query: 569 LLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPD-----DFDKDAKDLLIGLLCRDPKRRL 623
+YE+L G P+ ++ + IL + FP+ + K L+ LL +D +R
Sbjct: 371 FIYEILYGTTPFKGKNRHATFSNILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRC 430
Query: 624 G-YHGSDEIKSHPFFNQLSWKRLK-MKGYIPPYKPPVMGAMDTSNFDQE 670
G G+ +IK HPFF + W L+ MK I P M A++ S+ D E
Sbjct: 431 GSVAGASDIKQHPFFRHIQWALLRSMKPPIIPKIEDGMEAVEPSDNDNE 479
>Hs4885347 [T] KOG0986 G protein-coupled receptor kinase
Length = 500
Score = 192 bits (489), Expect = 1e-48
Identities = 107/279 (38%), Positives = 163/279 (58%), Gaps = 9/279 (3%)
Query: 386 KVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPL 445
+V+GKG FG+V + R T K+YA K ++K I + L E+ +L +V + F+V L
Sbjct: 159 RVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSL 218
Query: 446 KFSFQSSEKLYLVLAFINGGELFYHLQREGR--FDLSRSRFYTAELLCALEALHDFDIIY 503
+++++ + L LVL +NGG+L +H+ G FD R+ FY AEL C LE L I+Y
Sbjct: 219 AYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVY 278
Query: 504 RDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDW 563
RDLKPENILLD +GHI + D GL + + ++ GT Y+APE++ + YT DW
Sbjct: 279 RDLKPENILLDDRGHIRISDLGLA-TEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDW 337
Query: 564 WTLGVLLYEMLTGLPPY--YDEDV--PKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDP 619
W LG L+YEM+ G P+ Y E V ++ ++I D + + F +DAK + LL ++P
Sbjct: 338 WGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNP 397
Query: 620 KRRLGYHGSDE--IKSHPFFNQLSWKRLKMKGYIPPYKP 656
+RLG G +K HP F ++++RL+ PP+ P
Sbjct: 398 SKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCP 436
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 192 bits (488), Expect = 1e-48
Identities = 103/291 (35%), Positives = 166/291 (56%), Gaps = 11/291 (3%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
++ ++ D F +L+ IGKGSFGKV V+KRDT K+YA+K + K + + EV + E +
Sbjct: 15 NEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQI 74
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
+ +++PF+V L +SFQ E +++V+ + GG+L YHLQ+ F + Y EL AL
Sbjct: 75 MQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALAL 134
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELL- 552
E L + II+RD+KP+NILLD GH+ + DF + + +K E+ ++ GT Y+APE+
Sbjct: 135 EYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATV-VKGAERASSMAGTKPYMAPEVFQ 193
Query: 553 ----LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDV---PKMYKKILQDPLRFPDDFDK 605
G GY+ VDWW+LG+ YE+L G PY V ++ + + + + K
Sbjct: 194 VYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEILNMFKVERVHYSSTWCK 253
Query: 606 DAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
LL LL +DP+ R+ +I+S P+ ++W + K +P + P
Sbjct: 254 GMVALLRKLLTKDPESRVS--SLHDIQSVPYLADMNWDAVFKKALMPGFVP 302
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 190 bits (483), Expect = 6e-48
Identities = 108/283 (38%), Positives = 167/283 (58%), Gaps = 9/283 (3%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F +V+GKG FG+V + R T K+YA K + K I + + L E+ +L +V++ F
Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQF 245
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR--FDLSRSRFYTAELLCALEALHDF 499
+V L +++++ + L LVL +NGG+L +H+ G F+ R+ FY AE+LC LE LH
Sbjct: 246 VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRE 305
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTK 559
+ +YRDLKPENILLD GHI + D GL + + + + GT Y+APE+L Q Y
Sbjct: 306 NTVYRDLKPENILLDDYGHIRISDLGLA-VKIPEGDLIRGRVGTVGYMAPEVLNNQRYGL 364
Query: 560 VVDWWTLGVLLYEMLTGLPPY--YDEDVPK--MYKKILQDPLRFPDDFDKDAKDLLIGLL 615
D+W LG L+YEM+ G P+ E V + + +++L+ + F ++AK + LL
Sbjct: 365 SPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLL 424
Query: 616 CRDPKRRLG--YHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
+D K+RLG G+ E+K HPFF +++KRL+ PP+ P
Sbjct: 425 TKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVP 467
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 186 bits (473), Expect = 8e-47
Identities = 111/333 (33%), Positives = 186/333 (55%), Gaps = 20/333 (6%)
Query: 362 KLNLSVD-YKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVS 420
++N+ VD K D++++K + KG +G+V VR+ KIYA+K + K ++
Sbjct: 24 RINVPVDRLKEVVEAKTKPSDYEIVKNVAKGGYGEVFLVRRE---KIYAMKRVSKELVLK 80
Query: 421 KSEVTHTLAERTVLAR-VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDL 479
+ +AE+ + + + ++V + Q E LY ++ FI GG+ L +E +
Sbjct: 81 QPHTALFMAEKEAMVDCIGSEWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEE 140
Query: 480 SRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKD-QEKTT 538
RFY AE++ AL+ LH I+RDLKP+N+L+ GH+ L DFG C + MKD + +++
Sbjct: 141 DWVRFYAAEIVAALDELHKLGWIHRDLKPDNVLIGIDGHVKLADFGSC-IKMKDGKARSS 199
Query: 539 TFCGTPEYLAPELLLGQG----YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ 594
GTP+Y++P++L Y + VD+WTLGV++YEM+ G P+Y + + + Y++I +
Sbjct: 200 ITVGTPDYVSPDVLCSVNEECEYGEDVDFWTLGVIIYEMIYGTTPFYSDTLMETYRRITR 259
Query: 595 DPLRFPDDFDKDAKDLLIGLL-CRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
FP + L+ GL+ +D + R+ +EIKSH FF + W RL K PP
Sbjct: 260 VEFGFPFKVSPELTSLIEGLIAAKDRRMRI-----EEIKSHAFFEGVDWSRL--KELKPP 312
Query: 654 YKPPVMGAMDTSNF-DQEFTREQPVDSVVNDFL 685
+ P V G DTS+F D +F E+ +V +++
Sbjct: 313 FVPEVNGDSDTSHFVDTQFDAEKRKLNVKGNYM 345
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 185 bits (470), Expect = 2e-46
Identities = 98/249 (39%), Positives = 147/249 (58%), Gaps = 5/249 (2%)
Query: 376 HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA 435
+ +++++ V+G GSFG VM VR++ YA K + K +V +V H E+ VL
Sbjct: 39 YTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLN 98
Query: 436 RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
PF++ L S + + LYL+L +NGGELF + +R +F+ +RFY A++ ALE
Sbjct: 99 AARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEY 158
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
+H ++YRDLKPENILLD +G+I + DFG K + +T+T CGTPEYLAPE++ +
Sbjct: 159 MHKMHLMYRDLKPENILLDQRGYIKITDFGFTK---RVDGRTSTLCGTPEYLAPEIVQLR 215
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPY--YDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIG 613
Y K VDWW G+L+YE + G P+ ++ DV MY KI + P F + L+
Sbjct: 216 PYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVES 275
Query: 614 LLCRDPKRR 622
L+ D +R
Sbjct: 276 LMQVDTSKR 284
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 185 bits (470), Expect = 2e-46
Identities = 103/299 (34%), Positives = 168/299 (55%), Gaps = 8/299 (2%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
+ ++I + + +G G+FG+V V + ALK I+K +V + ++ H E+ V
Sbjct: 686 YSQVAISELKKIATLGCGAFGRVDLVAYNQ--QALALKIIKKIEVVKQDQIEHVYNEKNV 743
Query: 434 LARV-DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
+ + +PFIV L ++++ + +Y ++ GG+++ + + FD ++F ++ A
Sbjct: 744 MIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEA 803
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELL 552
+ LH IYRDLKPEN++L G+ L DFG K ++ EKT TF GTPEY+APE++
Sbjct: 804 FDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKF-VRQNEKTNTFAGTPEYVAPEII 862
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ--DPLRFPDDFDKDAKDL 610
L +G+ + VD+W LG+L+YE+L G P+ + K+Y++IL D + P K A+ L
Sbjct: 863 LDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHL 922
Query: 611 LIGLLCRDPKRRLGYH--GSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNF 667
+ L + P RLGY G +IK H +F L W+RLK+K P K P+ D F
Sbjct: 923 VRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTDLQYF 981
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 184 bits (467), Expect = 4e-46
Identities = 111/353 (31%), Positives = 176/353 (49%), Gaps = 51/353 (14%)
Query: 369 YKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTL 428
Y +S DF + +G+G +G V RKRDT +I ALK + KS + E+ H L
Sbjct: 195 YLRKRRTRISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVL 254
Query: 429 AERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAE 488
ER +L ++ ++V L ++FQ + +YL + F+ GG+ L G ++FY E
Sbjct: 255 TERDILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATE 314
Query: 489 LLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGL------------CKLNMKD--- 533
+ A++ALH I+RDLKPEN L+ GHI L DFGL K+ +++
Sbjct: 315 MFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIESMKIRLQEVNN 374
Query: 534 --------QEKTTTF--------------CGTPEYLAPELLLGQGYTKVVDWWTLGVLLY 571
+E+ F G+P+Y+APE+L G+ Y VD+W+LG ++Y
Sbjct: 375 VVVPERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNHSVDYWSLGCIMY 434
Query: 572 EMLTGLPPYYDEDVP------KMYKKILQDP-LRFPDDFDKDAKDLLIGLLCR---DPKR 621
E L+G PP+ +V K ++K Q P P D + + +D +C DPK
Sbjct: 435 ECLSGFPPFSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAWDFVCHCITDPKD 494
Query: 622 RLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
R + ++ HP+F+++ WK ++ Y PP+ P + +D FD +FT E
Sbjct: 495 R--FCSLKQVMQHPYFSKIDWKNVR-TAYRPPFVPDLNSEIDAGYFD-DFTNE 543
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 183 bits (465), Expect = 7e-46
Identities = 101/286 (35%), Positives = 160/286 (55%), Gaps = 11/286 (3%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ F +++ IG+G+FGKV V++R T K +ALK + K + K + + E T+L+++
Sbjct: 25 LQHFSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRCIEKGVAANVIRELTLLSKMS 84
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+PFIV L ++FQ + +Y+V + GG+L YHL ++G+F R++ Y E+ A+E LH+
Sbjct: 85 HPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRAKLYLCEICLAVEYLHE 144
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE-----LLL 553
I++RD+KPENILLD QGH L D L ++D + T++ GT Y+APE L +
Sbjct: 145 MKIVHRDIKPENILLDEQGHAHLTDLNLA-TQLEDDQLATSYSGTRPYMAPEIYATYLEI 203
Query: 554 GQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPK---MYKKILQDPLRFPDDFDKDAKDL 610
GY VDWW LGV YEML G P+ K Y + + +P + D
Sbjct: 204 EDGYDSRVDWWALGVCFYEMLRGRTPFEFSSRTKPEEAYVAFRESSIPYPAHWPTDLIQF 263
Query: 611 LIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
+ +L D ++RL G + IK H + ++ +K + K P + P
Sbjct: 264 INSMLKFDKEKRL--VGLEAIKKHSYTERIDFKSVFEKKPSPVFIP 307
>At1g16440 [R] KOG0610 Putative serine/threonine protein kinase
Length = 431
Score = 174 bits (441), Expect = 4e-43
Identities = 111/348 (31%), Positives = 173/348 (48%), Gaps = 70/348 (20%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKI--YALKAIRKSYIVSKSEVTHTLAERTVL 434
L I DF +LK +G G G V V + N +A+K + K+ +VS++++ ER +L
Sbjct: 40 LGISDFRVLKRLGYGDIGSVYLVELKGANPTTYFAMKVMDKASLVSRNKLLRAQTEREIL 99
Query: 435 ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR--FDLSRSRFYTAELLCA 492
+++D+PF+ L F++ + LV+ F +GG L+ Q++ F +RF+ +E+L A
Sbjct: 100 SQLDHPFLPTLYSHFETDKFYCLVMEFCSGGNLYSLRQKQPNKCFTEDAARFFASEVLLA 159
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGL---CKLN------------------- 530
LE LH I+YRDLKPEN+L+ GHI L DF L C +N
Sbjct: 160 LEYLHMLGIVYRDLKPENVLVRDDGHIMLSDFDLSLRCSVNPTLVKSFNGGGTTGIIDDN 219
Query: 531 --------------------MKDQEKTTTFCGT-PE------------------YLAPEL 551
K+++ + F G+ PE YLAPE+
Sbjct: 220 AAVQGCYQPSAFFPRMLQSSKKNRKSKSDFDGSLPELMAEPTNVKSMSFVGTHEYLAPEI 279
Query: 552 LLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPD--DFDKDAKD 609
+ +G+ VDWWT G+ +YE+L G P+ + ++ PLRFP+ AKD
Sbjct: 280 IKNEGHGSAVDWWTFGIFIYELLHGATPFKGQGNKATLYNVIGQPLRFPEYSQVSSTAKD 339
Query: 610 LLIGLLCRDPKRRLGY-HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
L+ GLL ++P+ R+ Y G+ EIK HPFF ++W + +G PP+ P
Sbjct: 340 LIKGLLVKEPQNRIAYKRGATEIKQHPFFEGVNWALI--RGETPPHLP 385
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 172 bits (437), Expect = 1e-42
Identities = 96/275 (34%), Positives = 157/275 (56%), Gaps = 6/275 (2%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
K LS+DDF+L K +GKG FGKV VR R T I ALK + K I+ + E +
Sbjct: 97 KSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQ 156
Query: 435 ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
+++P + F +++YL++ ++ GE++ L+ G F+ + Y ++ AL+
Sbjct: 157 TSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALD 216
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
+H +II+RD+KPENIL+ + I L DFG +N + + T CGT +YL+PE++
Sbjct: 217 YMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTV-CGTIDYLSPEMVES 275
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGL 614
+ Y +D W LGVL +E+LTG PP+ +E YK+I ++ P + +DA+DL++ L
Sbjct: 276 REYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKL 335
Query: 615 LCRDPKRRLGYHGSDEIKSHPFF--NQLSWKRLKM 647
L DPK R+ ++K HP+ N+ W+ ++
Sbjct: 336 LKYDPKDRMRL---GDVKMHPWILRNKPFWENKRL 367
>At3g12690 [R] KOG0610 Putative serine/threonine protein kinase
Length = 577
Score = 172 bits (436), Expect = 2e-42
Identities = 112/350 (32%), Positives = 168/350 (48%), Gaps = 73/350 (20%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ +D+F LLK +G G G V R TN ++A+K + K+ + S++++ ER +L+
Sbjct: 180 IGLDNFRLLKRLGYGDIGSVYLADLRGTNAVFAMKVMDKASLASRNKLLRAQTEREILSL 239
Query: 437 VDNPFIVPLKFSFQSSEKLY-LVLAFINGGELFYHLQRE--GRFDLSRSRFYTAELLCAL 493
+D+PF+ P +S+ ++K Y LV+ F +GG L Q++ RF +RFY +E+L AL
Sbjct: 240 LDHPFL-PTLYSYFETDKFYCLVMEFCSGGNLHSLRQKQPSRRFTEEAARFYASEVLLAL 298
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGL---CKLN---------------MKDQE 535
E LH ++YRDLKPENIL+ +GHI L DF L C N + ++E
Sbjct: 299 EYLHMLGVVYRDLKPENILVRDEGHIMLSDFDLSLRCTFNPTLVKSSSVCSGGGAILNEE 358
Query: 536 KTTTFCGTPEYLAPELL------------------------------------------- 552
C P P LL
Sbjct: 359 FAVNGCMHPSAFLPRLLPSKKTRKAKSDSGLGGLSMPELMAEPTDVRSMSFVGTHEYLAP 418
Query: 553 ---LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPD--DFDKDA 607
G+G+ VDWWT G+ LYE+L G P+ + ++ PL+FPD A
Sbjct: 419 EIIRGEGHGSAVDWWTFGIFLYELLHGTTPFKGQGNRATLHNVVGQPLKFPDTPHVSSAA 478
Query: 608 KDLLIGLLCRDPKRRLGY-HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
+DL+ GLL +DP RR+ Y G+ EIK HPFF ++W ++ PP+ P
Sbjct: 479 RDLIRGLLVKDPHRRIAYTRGATEIKQHPFFEGVNWALVRSAA--PPHIP 526
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 171 bits (434), Expect = 3e-42
Identities = 100/266 (37%), Positives = 147/266 (54%), Gaps = 4/266 (1%)
Query: 373 THKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERT 432
T K + +++ + IG+G+F KV R DT A+K + KS I+ V E +
Sbjct: 2 TKKMRRVGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREIS 61
Query: 433 VLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCA 492
++ V +P IV L S K+Y+VL F+ GGELF + +GR + S SR Y +L+ A
Sbjct: 62 IMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDA 121
Query: 493 LEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELL 552
+ H + +RDLKPEN+LLD G++ + DFGL L + E T CGTP Y+APE+L
Sbjct: 122 VAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVL 181
Query: 553 LGQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLL 611
GQGY D W+ GV+L+ +L G P+ + D+P +Y+KI P F + K L+
Sbjct: 182 SGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLI 241
Query: 612 IGLLCRDPKRRLGYHGSDEIKSHPFF 637
+L +PK R+ G IK P+F
Sbjct: 242 HRILDPNPKTRIQIQG---IKKDPWF 264
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 168 bits (426), Expect = 2e-41
Identities = 98/268 (36%), Positives = 156/268 (57%), Gaps = 10/268 (3%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-E 430
+T K S+ DF++ + +GKG FG+V R+ + I ALK I K I K ++ H L E
Sbjct: 12 NTEKQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQI-EKYKIHHQLRRE 70
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+ + +P I+ L F +E+++L+L + +GGEL+ L++ G ++ Y A L
Sbjct: 71 MEIQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLS 130
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
AL H +I+RD+KPEN+LLD++G + + DFG +++ K T CGT +YLAPE
Sbjct: 131 QALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFG---WSVQSSNKRKTMCGTLDYLAPE 187
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP--DDFDKDAK 608
++ + + VD WTLG+L YE L G PP+ E +K+IL+ L FP + ++AK
Sbjct: 188 MVENRDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAK 247
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPF 636
+L+ LL +DP +RL ++I HP+
Sbjct: 248 NLISQLLVKDPSKRLSI---EKIMQHPW 272
>At2g34650 [R] KOG0610 Putative serine/threonine protein kinase
Length = 438
Score = 166 bits (421), Expect = 9e-41
Identities = 110/334 (32%), Positives = 162/334 (47%), Gaps = 64/334 (19%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVR-----KRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
L+ DF L++ IG G G V R + + +A+K + K + K ++ E+
Sbjct: 70 LTFRDFRLMRRIGAGDIGTVYLCRLAGDEEESRSSYFAMKVVDKEALALKKKMHRAEMEK 129
Query: 432 TVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGEL--FYHLQREGRFDLSRSRFYTAEL 489
T+L +D+PF+ L F++S +V+ + +GG+L H Q RF LS +RFY AE+
Sbjct: 130 TILKMLDHPFLPTLYAEFEASHFSCIVMEYCSGGDLHSLRHRQPHRRFSLSSARFYAAEV 189
Query: 490 LCALEALHDFDIIYRDLKPENILLDYQGHIALCDF--GLCKLNMKDQEKTT--------- 538
L ALE LH IIYRDLKPENIL+ GHI L DF LC ++ E ++
Sbjct: 190 LVALEYLHMLGIIYRDLKPENILVRSDGHIMLSDFDLSLCSDSIAAVESSSSSPENQQLR 249
Query: 539 ----------------------------------------TFCGTPEYLAPELLLGQGYT 558
+F GT EY+APE+ G +
Sbjct: 250 SPRRFTRLARLFQRVLRSKKVQTLEPTRLFVAEPVTARSGSFVGTHEYVAPEVASGGSHG 309
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD-----FDKDAKDLLIG 613
VDWW GV LYEM+ G P+ + + I++ L FP D F+ A++L+ G
Sbjct: 310 NAVDWWAFGVFLYEMIYGKTPFVAPTNDVILRNIVKRQLSFPTDSPATMFELHARNLISG 369
Query: 614 LLCRDPKRRLG-YHGSDEIKSHPFFNQLSWKRLK 646
LL +DP +RLG G+ E+K HPFF L++ ++
Sbjct: 370 LLNKDPTKRLGSRRGAAEVKVHPFFKGLNFALIR 403
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 165 bits (418), Expect = 2e-40
Identities = 98/280 (35%), Positives = 153/280 (54%), Gaps = 13/280 (4%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTV 433
+ L++DDF++ + +GKG FG V R ++++ I ALK + KS I K + H L E +
Sbjct: 2 RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQI-EKEGLEHQLRREIEI 60
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
A + +P I+ L F + ++YL+L + GEL+ LQ+ + D R+ E+ AL
Sbjct: 61 QAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADAL 120
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLL 553
HD +I+RD+KPEN+LL ++G + + DFG + K T CGT +YL PE++
Sbjct: 121 TYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERK--TMCGTLDYLPPEMIE 178
Query: 554 GQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIG 613
G+ Y + VD W +GVL YE+L G PP+ + Y++IL+ +RFP A+DL+
Sbjct: 179 GRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISR 238
Query: 614 LLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
LL P RL +I HP W + + +PP
Sbjct: 239 LLRYQPLERLPL---AQILKHP------WVQAHSRRVLPP 269
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 164 bits (414), Expect = 6e-40
Identities = 116/406 (28%), Positives = 183/406 (44%), Gaps = 61/406 (15%)
Query: 316 DYVKKIRNNSDIHLDSFHLPLNLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPSTHK 375
DYV R + L+ +L ++ ++ I+L N W + ++ KP
Sbjct: 120 DYVISRRQRTKQVLE--YLQQQSQLPNSDQIKL-NEEWSSYLQREHQVLRKRRLKPKNR- 175
Query: 376 HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA 435
DF+++ +G+G +G+V RK+DT ++ ALK + K + +E H L ER +L
Sbjct: 176 -----DFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILT 230
Query: 436 RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
+ ++V L ++FQ + LYL + F+ GG+ L +RFY +E+ CA+ A
Sbjct: 231 TTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNA 290
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLC---------------------------- 527
LHD +RDLKPEN L+D +GHI L DFGL
Sbjct: 291 LHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFT 350
Query: 528 ------------KLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLT 575
+L K+ + G+P+Y+A E+L G+ Y VD+W+LG +L+E L
Sbjct: 351 EKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLV 410
Query: 576 GLPPYYDEDVPKMYKKI--LQDPLRFPDDFD-----KDAKDLLIGLLCRDPKRRLGYHGS 628
G P+ + Y + + LR P D D LI L DP RL
Sbjct: 411 GYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRL--RSF 468
Query: 629 DEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
+ +K +F +++ L + IPP+ P + D FD +FT E
Sbjct: 469 EHVKRMSYFADINFSTL--RSMIPPFTPQLDSETDAGYFD-DFTSE 511
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 164 bits (414), Expect = 6e-40
Identities = 94/264 (35%), Positives = 154/264 (57%), Gaps = 15/264 (5%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F ++V+G G+F +V V++R T K++ALK I+KS S + + +A VL ++ +
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIA---VLKKIKHEN 79
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
IV L+ ++S+ YLV+ ++GGELF + G + + ++L A++ LH+ I
Sbjct: 80 IVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGI 139
Query: 502 IYRDLKPENILL---DYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
++RDLKPEN+L + I + DFGL K M+ +T CGTP Y+APE+L + Y+
Sbjct: 140 VHRDLKPENLLYLTPEENSKIMITDFGLSK--MEQNGIMSTACGTPGYVAPEVLAQKPYS 197
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP----DDFDKDAKDLLIGL 614
K VD W++GV+ Y +L G PP+Y+E K+++KI + F DD + AKD + L
Sbjct: 198 KAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHL 257
Query: 615 LCRDPKRRLGYHGSDEIKSHPFFN 638
L +DP R + ++ SHP+ +
Sbjct: 258 LEKDPNER---YTCEKALSHPWID 278
>At3g14370 [R] KOG0610 Putative serine/threonine protein kinase
Length = 480
Score = 164 bits (414), Expect = 6e-40
Identities = 114/369 (30%), Positives = 178/369 (47%), Gaps = 68/369 (18%)
Query: 342 SASNIRLYNHHWIELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRK 401
S+ N R ++ HW ++S KL S+ ++ + L++ +G G+ G+V
Sbjct: 57 SSVNHRRHDPHWSAIKS--AKLL-------SSDGNIHLRHLKLIRHLGTGNLGRVFLCNL 107
Query: 402 RDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAF 461
RD++ +ALK I ++ + ++ +++ E +L+ +D+PF+ L S L++ +
Sbjct: 108 RDSSARFALKVIDRNCLTTEKKLSQVETEAEILSLLDHPFLPTLYARIDESHYTCLLIDY 167
Query: 462 INGGELFYHLQRE--GRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHI 519
G+L L+++ R + RF+ AE+L ALE LH I+YRDLKPEN+LL GH+
Sbjct: 168 APNGDLHSLLRKQPGNRLPIQPVRFFAAEVLVALEYLHAMGIVYRDLKPENVLLREDGHV 227
Query: 520 ALCDFGLC-------------------------------------KLNMKD------QEK 536
L DF LC K ++ E
Sbjct: 228 MLSDFDLCFKSDVVPTFKSRRYRRSSSSPSLRRRRSGCFSVAAEKKYEREEIVSEFAAEP 287
Query: 537 TTTF----CGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKI 592
T F GT EYLAPEL+ G G+ VDWW G+ LYE+L G P+ E + + I
Sbjct: 288 VTAFSRSCVGTHEYLAPELVSGNGHGSGVDWWAFGIFLYELLYGTTPFKGESKEQTLRNI 347
Query: 593 LQ--DPLRFPDDFDKD-AKDLLIGLLCRDPKRRLG-YHGSDEIKSHPFFNQLSWKRLKMK 648
+ F D D D A+DL+ LL +DP++RLG G+ +IK HPFF+ + W ++
Sbjct: 348 VSTTKTASFHMDGDLDEARDLIEKLLVKDPRKRLGCARGAQDIKRHPFFDGIKWPLIR-- 405
Query: 649 GYIPPYKPP 657
YKPP
Sbjct: 406 ----HYKPP 410
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 163 bits (413), Expect = 7e-40
Identities = 97/273 (35%), Positives = 147/273 (53%), Gaps = 8/273 (2%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVL 434
+ I F++ K +GKG FG+V +++ T I ALK + KS +V E +
Sbjct: 111 REFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQ 170
Query: 435 ARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
+ + + I+ L F +++YL+L F GEL+ HL+R RF + Y ++ AL
Sbjct: 171 SNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALS 230
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
LH +I+RD+KPENILL G I L DFG + TT CGT +YL PE++ G
Sbjct: 231 YLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSV--HAPSNRRTTLCGTLDYLPPEMVEG 288
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYD-EDVPKMYKKILQDPLRFPDDFDKDAKDLLIG 613
+ +T+ VD W+LGVL YE L G PP+ D YK+I + L+ P DA+DL+
Sbjct: 289 KEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISR 348
Query: 614 LLCRDPKRRLGYHGSDEIKSHPFFNQL--SWKR 644
LL +P++R+ +++ HP+ + SW R
Sbjct: 349 LLQHNPEKRMSL---EQVMRHPWIVKYKDSWTR 378
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 163 bits (413), Expect = 7e-40
Identities = 99/280 (35%), Positives = 152/280 (53%), Gaps = 13/280 (4%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTV 433
+H +IDDF++ + +GKG FG V R++ ++ I ALK + KS I K V H L E +
Sbjct: 70 RHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQI-EKEGVEHQLRREIEI 128
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
A + +P I+ L F ++YL+L + GEL+ LQ+ FD R+ EL AL
Sbjct: 129 QAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADAL 188
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLL 553
H +I+RD+KPEN+LL +G + + DFG + K T CGT +YL PE++
Sbjct: 189 MYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRK--TMCGTLDYLPPEMIE 246
Query: 554 GQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIG 613
G+ + + VD W +GVL YE+L G PP+ + Y++I++ L+FP A+DL+
Sbjct: 247 GRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISK 306
Query: 614 LLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
LL +P RL ++ +HP W R + +PP
Sbjct: 307 LLRHNPSERLPL---AQVSAHP------WVRANSRRVLPP 337
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 162 bits (410), Expect = 2e-39
Identities = 127/399 (31%), Positives = 182/399 (44%), Gaps = 74/399 (18%)
Query: 348 LYNHHWIELESKMGKLNLSVDYKPST-----HKHLSIDDFDLLKVIGKGSFGKVMQVRKR 402
L +H+W E E K +L+ S+ K S LS++DF +KVIGKG+FG+V V+K+
Sbjct: 315 LTSHNWSE-ERKSRQLS-SLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKK 372
Query: 403 DTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFI 462
DT KIYA+K + KS + K ++ H AER VLA D+P++V L +SFQ ++ LYL++ F+
Sbjct: 373 DTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFL 432
Query: 463 NGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALC 522
GG+L L R F +RFY AE + A+E +H I+RD+KP+NIL+D +GHI L
Sbjct: 433 PGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLS 492
Query: 523 DFGLC------------KLNMKDQEKTTTFCGTPEYLAPEL-LLGQGYTKVVD------- 562
DFGL K ++ E T Y A + T VVD
Sbjct: 493 DFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMS 552
Query: 563 -------WWTLGVLLYEMLTGLPPYYDEDV--------------------------PKMY 589
W L+ G P Y ++ P
Sbjct: 553 NRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFC 612
Query: 590 KKILQDPLRFPDDFDKDAK---DLLIGLLCRDPKRRLGYH---------GSDEIKSHPFF 637
+ Q+ R +F++ + D+ I D RRL H G+DEIKSHPFF
Sbjct: 613 SETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFF 672
Query: 638 NQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQP 676
+ W ++ PY P + DT F + P
Sbjct: 673 RGVDWNTIRQ--VEAPYIPKLSSITDTRFFPTDELENVP 709
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 162 bits (410), Expect = 2e-39
Identities = 89/271 (32%), Positives = 153/271 (55%), Gaps = 14/271 (5%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTVLARVD 438
D +++ +++G G+F KV + T A+K I+K ++ + + + E V+ +
Sbjct: 13 DKYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLR 72
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P +V L+ + +K++ V+ ++NGGELF + R+G+ +R Y +L+ A++ H
Sbjct: 73 HPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHS 132
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKD---------QEKTTTFCGTPEYLAP 549
+ +RD+KPEN+LLD +G + + DFGL L M + + T CGTP Y+AP
Sbjct: 133 RGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAP 192
Query: 550 ELLLGQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
E+L +GY + D W+ G++LY +L G P+ DE+V +Y KI + FP F ++K
Sbjct: 193 EVLRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLESK 252
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQ 639
+LL LL DP++R+ EIK P+F +
Sbjct: 253 ELLSRLLVPDPEQRI---SMSEIKMIPWFRK 280
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 161 bits (408), Expect = 3e-39
Identities = 90/254 (35%), Positives = 144/254 (56%), Gaps = 4/254 (1%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
S H+ L + +++ +++G G+F KV R + + A+K I K ++ + H E
Sbjct: 18 SNHQALILGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHIKREI 77
Query: 432 TVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
++L RV +P IV L + K+Y V+ ++ GGELF + + GR +R Y +L+
Sbjct: 78 SILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAK-GRLKEEMARKYFQQLIS 136
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLN--MKDQEKTTTFCGTPEYLAP 549
A+ H + +RDLKPEN+LLD G++ + DFGL ++ ++ TFCGTP Y+AP
Sbjct: 137 AVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAP 196
Query: 550 ELLLGQGYTKV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
E+L +GY VD W+ GV+L+ ++ G P++D +V MYKKI + R P F +
Sbjct: 197 EVLARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGDFRCPRWFPVEIN 256
Query: 609 DLLIGLLCRDPKRR 622
LLI +L P+RR
Sbjct: 257 RLLIRMLETKPERR 270
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 161 bits (407), Expect = 4e-39
Identities = 95/265 (35%), Positives = 152/265 (56%), Gaps = 9/265 (3%)
Query: 375 KHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTV 433
K +++FD+ +++G+G FG V R++++ + ALK + K I +S V H + E +
Sbjct: 147 KTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQI-GESNVEHQVRREIEI 205
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREG--RFDLSRSRFYTAELLC 491
+ + +P I+ L F ++YL+L + G LF LQ + RFD +S Y L
Sbjct: 206 QSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCS 265
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPEL 551
AL LH+ DII+RD+KPEN+LL ++G + + DFG + T CGT +YL PE+
Sbjct: 266 ALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSV--HEPNSMRMTLCGTVDYLPPEM 323
Query: 552 LLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLL 611
+ G+ +TK VD W+LGVL +E+L G P+Y ++ + YKKIL+ + P+ K A L+
Sbjct: 324 VQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLI 383
Query: 612 IGLLCRDPKRRLGYHGSDEIKSHPF 636
LL +P+ RL D++ HP+
Sbjct: 384 SKLLVLNPQHRLPL---DQVMVHPW 405
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 160 bits (406), Expect = 5e-39
Identities = 97/254 (38%), Positives = 148/254 (58%), Gaps = 18/254 (7%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
D +D V+G G+F +V+ + T K+ A+K I K + K E VL ++ +
Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMEN--EIAVLHKIKH 75
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRF---DLSRSRFYTAELLCALEAL 496
P IV L ++S LYL++ ++GGELF + +G + D SR F ++L A++ L
Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIF---QVLDAVKYL 132
Query: 497 HDFDIIYRDLKPENIL---LDYQGHIALCDFGLCKLNMKDQEKT-TTFCGTPEYLAPELL 552
HD I++RDLKPEN+L LD I + DFGL K M+D +T CGTP Y+APE+L
Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVLSTACGTPGYVAPEVL 190
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP----DDFDKDAK 608
+ Y+K VD W++GV+ Y +L G PP+YDE+ K++++IL+ F DD AK
Sbjct: 191 AQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAK 250
Query: 609 DLLIGLLCRDPKRR 622
D + L+ +DP++R
Sbjct: 251 DFIRHLMEKDPEKR 264
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 160 bits (406), Expect = 5e-39
Identities = 87/246 (35%), Positives = 140/246 (56%), Gaps = 1/246 (0%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ ++L + IG+G+F KV + +T + A+K + +S I+ + V E +++ V
Sbjct: 6 VGKYELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVR 65
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P +V L S K+Y++L +I GGELF + R GR S +R Y +L+ ++ H
Sbjct: 66 HPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHS 125
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+ +RDLKPEN+LLD QG++ + DFGL L + T CGTP Y+APE+L +GY
Sbjct: 126 KGVYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGYN 185
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
V D W+ GV+LY ++ G P+ + D+P +Y KI + P F AK L+ +L
Sbjct: 186 GAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCPSYFALGAKSLINRILDP 245
Query: 618 DPKRRL 623
+P+ R+
Sbjct: 246 NPETRI 251
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 160 bits (404), Expect = 8e-39
Identities = 102/352 (28%), Positives = 172/352 (47%), Gaps = 54/352 (15%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DF +L +G+G +G+V +K+D+++I ALK + K + +E H L ER +L +
Sbjct: 168 DFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSD 227
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
++V L ++FQ E LYL + F+ GG+ L +RFY +E+ CA+ ALH+
Sbjct: 228 WLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELG 287
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLC----------------------------KLNMK 532
+RDLKPEN L+D GHI L DFGL + +++
Sbjct: 288 YTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIE 347
Query: 533 DQEK------------TTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPY 580
D+ K + G+P+Y+A E+L G+ Y VD+W+LG +L+E L G P+
Sbjct: 348 DRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPF 407
Query: 581 YDEDVPKMYKKI--LQDPLRFPDDFDKDAK------DLLIGLLCRDPKRRLGYHGSDEIK 632
+ Y+ + + LR P D+ A DL+ L+ DP R+ ++++
Sbjct: 408 SGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIA-DPINRV--RSFEQVR 464
Query: 633 SHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQPVDSVVNDF 684
+F +++++ L+ PP+ P + D FD +FT E+ + + F
Sbjct: 465 KMSYFAEINFETLRTSS--PPFIPQLDDETDAGYFD-DFTNEEDMAKYADVF 513
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 159 bits (403), Expect = 1e-38
Identities = 97/284 (34%), Positives = 159/284 (55%), Gaps = 8/284 (2%)
Query: 366 SVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVT 425
S+ + S+ + L + +++ K++G G+F KV R TN+ A+K I K ++ +
Sbjct: 10 SLPKERSSPQALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIA 69
Query: 426 HTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFY 485
H E ++L RV +P IV L + K+Y V+ ++ GGELF + + GR +R Y
Sbjct: 70 HIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAK-GRLKEEVARKY 128
Query: 486 TAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLN--MKDQEKTTTFCGT 543
+L+ A+ H + +RDLKPEN+LLD G++ + DFGL ++ ++ TFCGT
Sbjct: 129 FQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGT 188
Query: 544 PEYLAPELLLGQGYTKV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD 602
P Y+APE+L +GY VD W+ GV+L+ ++ G P++D +V MYKKI + R P
Sbjct: 189 PAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPRW 248
Query: 603 FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLK 646
F + LL LL +P++R + EI + +F + +K +K
Sbjct: 249 FSTELTRLLSKLLETNPEKRFTF---PEIMENSWFKK-GFKHIK 288
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 159 bits (402), Expect = 1e-38
Identities = 91/269 (33%), Positives = 150/269 (54%), Gaps = 7/269 (2%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTVLARVDNP 440
++L K++G G+F KV R R T + A+K + K +++ + + + E +++ R+ +P
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
IV L + K++ + F+ GGELF + + GR SR Y +L+ A+ H
Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCKL--NMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+ +RDLKPEN+L+D G++ + DFGL L ++ T CGTP Y+APE+L +GY
Sbjct: 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE 200
Query: 559 KV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+ G++L+ ++ G P+ D +V MYKKI + RFP D K + LL
Sbjct: 201 GAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDI 260
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLK 646
+P+ R+ DEI P+F + +K++K
Sbjct: 261 NPETRITI---DEILKDPWFVRGGFKQIK 286
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 158 bits (400), Expect = 2e-38
Identities = 90/262 (34%), Positives = 148/262 (56%), Gaps = 13/262 (4%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
F+ + +G G+F +V+ ++ T K++A+K I K + K E VL ++ +
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIEN--EIAVLRKIKHEN 80
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
IV L+ ++S LYLV+ ++GGELF + +G + + ++L A+ LH I
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140
Query: 502 IYRDLKPENILL---DYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
++RDLKPEN+L D + I + DFGL K+ K +T CGTP Y+APE+L + Y+
Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTA-CGTPGYVAPEVLAQKPYS 199
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP----DDFDKDAKDLLIGL 614
K VD W++GV+ Y +L G PP+YDE+ K++++IL+ F DD AKD + L
Sbjct: 200 KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNL 259
Query: 615 LCRDPKRRLGYHGSDEIKSHPF 636
+ +DP +R + ++ HP+
Sbjct: 260 MEKDPNKR---YTCEQAARHPW 278
>At1g53700 [R] KOG0610 Putative serine/threonine protein kinase
Length = 476
Score = 158 bits (399), Expect = 3e-38
Identities = 114/364 (31%), Positives = 173/364 (47%), Gaps = 69/364 (18%)
Query: 347 RLYNHHWIELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNK 406
R Y+ HW + + LS D + L + F L++ +G G+ G+V RD
Sbjct: 67 RRYDPHWTSIRAAT---TLSSDGR------LHLRHFKLVRHLGTGNLGRVFLCHLRDCPN 117
Query: 407 I--YALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFING 464
+ALK I + + +K +++H E +L+ +D+PF+ L +S L++ +
Sbjct: 118 PTGFALKVIDRDVLTAK-KISHVETEAEILSLLDHPFLPTLYARIDASHYTCLLIDYCPN 176
Query: 465 GELFYHLQRE--GRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALC 522
G+L L+++ R +S RF+ AE+L ALE LH I+YRDLKPENIL+ GHI L
Sbjct: 177 GDLHSLLRKQPNNRLPISPVRFFAAEVLVALEYLHALGIVYRDLKPENILIREDGHIMLS 236
Query: 523 DFGLC---------------------------------KLNMKDQEKTTTFC-------- 541
DF LC ++ + +E F
Sbjct: 237 DFDLCFKADVVPTFRSRRFRRTSSSPRKTRRGGGCFSTEVEYEREEIVAEFAAEPVTAFS 296
Query: 542 ----GTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL-QDP 596
GT EYLAPEL+ G G+ VDWW G+ LYEML G P+ + + I+ D
Sbjct: 297 KSCVGTHEYLAPELVAGNGHGSGVDWWAFGIFLYEMLYGTTPFKGGTKEQTLRNIVSNDD 356
Query: 597 LRF--PDDFDKDAKDLLIGLLCRDPKRRLG-YHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
+ F ++ +AKDL+ LL +DP++RLG G+ +IK H FF + W ++
Sbjct: 357 VAFTLEEEGMVEAKDLIEKLLVKDPRKRLGCARGAQDIKRHEFFEGIKWPLIR------N 410
Query: 654 YKPP 657
YKPP
Sbjct: 411 YKPP 414
>At1g51170 [R] KOG0610 Putative serine/threonine protein kinase
Length = 404
Score = 157 bits (398), Expect = 4e-38
Identities = 119/376 (31%), Positives = 172/376 (45%), Gaps = 78/376 (20%)
Query: 366 SVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVM----QVRKRDTNKIYALKAIRKSYIVSK 421
S P+T+ L++D +LK++GKG+ G V V + +ALK + KS S
Sbjct: 8 SSSLSPATN--LNLDRLKVLKLLGKGATGTVFLVHDSVSDSSVSSPFALKLVDKS---SA 62
Query: 422 SEVTHTLAERTVLARVD-----NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQRE-- 474
S + E +L R+ NPF+ L S +SSE + L + +GG+L QR+
Sbjct: 63 SSLRRARWEIQILRRLSDDTNPNPFLPKLLASSESSEFIAWALPYCSGGDLNVLRQRQND 122
Query: 475 GRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGL-CKLN--- 530
G F S +FY AE++CAL+ LH I YRDLKPENILL GH+ L DF L C LN
Sbjct: 123 GVFSSSVIKFYLAEIVCALDHLHTMGIAYRDLKPENILLQESGHVTLTDFDLSCSLNKPT 182
Query: 531 ------MKDQE---------------------------------------------KTTT 539
+ D E ++ +
Sbjct: 183 RPEFYHLSDPEPDPNPESNLSHNKKSLRIFRQKKKKTKSARVNPITRRRLSFSGGERSNS 242
Query: 540 FCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRF 599
F GT EY++PE++ G G+ VDWW LGVL YEM+ G P+ + + ++ +L F
Sbjct: 243 FVGTDEYISPEVIRGDGHDFAVDWWALGVLTYEMMYGETPFKGRNKKETFRNVLVKEPEF 302
Query: 600 PDDFDKDAKDLLIGLLCRDPKRRLGY-HGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV 658
D DL+ LL +DP +R G+ G+ EIK H FF + W+ L +PP
Sbjct: 303 AGK-PSDLTDLIRRLLVKDPTKRFGFWRGAAEIKEHAFFKGVRWELL-----TEVLRPPF 356
Query: 659 MGAMDTSNFDQEFTRE 674
+ D + + T E
Sbjct: 357 IPLRDDGDLTGKVTEE 372
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 157 bits (398), Expect = 4e-38
Identities = 89/255 (34%), Positives = 142/255 (54%), Gaps = 4/255 (1%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
S ++ + ++L K++G G+F KV + + A+K I K I+ V H E
Sbjct: 64 SPRNNILMGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREI 123
Query: 432 TVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
++L RV +P+IV L + K+Y V+ ++ GGELF + +GR +R Y +L+
Sbjct: 124 SILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGELF-NTVAKGRLPEETARRYFQQLIS 182
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKL--NMKDQEKTTTFCGTPEYLAP 549
++ H + +RDLKPEN+LLD +G++ + DFGL + ++ TFCGTP Y+AP
Sbjct: 183 SVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAP 242
Query: 550 ELLLGQGYTKV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
E+L +GY D W+ GV+L+ ++ G P+YD+++ MYKKI + R P F D
Sbjct: 243 EVLTRKGYDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLV 302
Query: 609 DLLIGLLCRDPKRRL 623
LL LL +P R+
Sbjct: 303 RLLTRLLDTNPDTRI 317
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 157 bits (396), Expect = 7e-38
Identities = 100/295 (33%), Positives = 150/295 (49%), Gaps = 17/295 (5%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN- 439
D+ +IG GSF KV + + + K YA+K + K YIV +++V + ER + R++
Sbjct: 53 DYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGF 112
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
P I L +FQ KLY VL GEL ++++ D + RFY AE+L ++E +H
Sbjct: 113 PGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSC 172
Query: 500 DIIYRDLKPENILLDYQGHIALCDFGLCKL----NMKDQEKTT---TFCGTPEYLAPELL 552
II+RDLKPENIL D H+ + DFG K+ + + TT +F GT EY+APELL
Sbjct: 173 GIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELL 232
Query: 553 LGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
Q +K D W ++Y+M+ G PP++ + ++KKI+ P D L
Sbjct: 233 SRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPKLLPPDIVPLFS 292
Query: 613 GLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRL------KMKGYIPPYKPPVMGA 661
L P R + +IK PFF ++W L M+ + P Y + A
Sbjct: 293 HLFRIQPSDR---STTQQIKQFPFFATITWDNLWTQDPPPMQSFRPNYNIAIPNA 344
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 157 bits (396), Expect = 7e-38
Identities = 95/347 (27%), Positives = 172/347 (49%), Gaps = 52/347 (14%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD- 438
+DF L+ +G+G++ +V + R+ T+ ++A+K ++KSY+ ++ + E+ +L +
Sbjct: 67 NDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQ 126
Query: 439 ----NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
+PF+ L F ++Y V+ + G+L L G FD+ S+F+ +E+L L+
Sbjct: 127 ECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQ 186
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK-------------------------- 528
LHD I++RD+KP+N+L+ GHI + DFG +
Sbjct: 187 FLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSG 246
Query: 529 -------LNMKDQEKT---TTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLP 578
+ +++E T TTF GT Y++PE+L D W LG +L++ L G P
Sbjct: 247 SPPPTRFYSDEEEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAGQP 306
Query: 579 PYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFN 638
P+ + + K+I + FP+ F ++A +++ +L RDP R+ S E+ +H FF
Sbjct: 307 PFRAVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPSTRI---TSQELMAHKFFE 363
Query: 639 QLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQE--FTREQPVDSVVND 683
+ W I KPPV+ A + F + ++ PV+ ++D
Sbjct: 364 NVDWVN------IANIKPPVLHAYIPATFGEPEYYSNIGPVEPGLDD 404
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 157 bits (396), Expect = 7e-38
Identities = 91/264 (34%), Positives = 138/264 (51%), Gaps = 5/264 (1%)
Query: 371 PSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
P +I+DF++ + +GKG FG V R + + A+K + KS ++S E
Sbjct: 19 PQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLERE 78
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+ + +++P I+ L F ++K+YLVL + GGE++ L RF + Y E+
Sbjct: 79 IEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIA 138
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
AL H ++I+RD+KPEN+L+ QG + + DFG K T CGT +YL PE
Sbjct: 139 DALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSV--HAPSNKRQTMCGTMDYLPPE 196
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
++ G ++ VD W +GVL YE L G PP+ ED K Y I +PD K A+DL
Sbjct: 197 MVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDL 256
Query: 611 LIGLLCRDPKRRLGYHGSDEIKSH 634
+ LL DPK R +++K H
Sbjct: 257 IGRLLVVDPKARCTL---EQVKEH 277
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 156 bits (395), Expect = 9e-38
Identities = 88/258 (34%), Positives = 153/258 (59%), Gaps = 5/258 (1%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
++ + +L++IG+GSFG+V + R++ + ++ ALK I K S+ E+ + E ++ +
Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGR-SEKELRNLQREIEIMRGLR 59
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P IV + SF++ +++ +V + G ELF L+ +G+ + + A+L+ AL LH
Sbjct: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I++RD+KP+NILL G I LCDFG + + T+ GTP Y++PEL+ + Y
Sbjct: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
D W++G +LYE+ G PP+Y + ++ IL+DP+R+P K+ L GLL +D
Sbjct: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
Query: 619 PKRRLGYHGSDEIKSHPF 636
P++RL + ++ HPF
Sbjct: 239 PRQRLSW---PDLLYHPF 253
>At3g20830 [R] KOG0610 Putative serine/threonine protein kinase
Length = 408
Score = 156 bits (394), Expect = 1e-37
Identities = 114/349 (32%), Positives = 160/349 (45%), Gaps = 74/349 (21%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQ----VRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERT 432
L +D LK++GKG+ G V V ++ +A+K + KS S S + E
Sbjct: 16 LDLDSIKALKILGKGATGTVFLAHDVVSTSSSSSPFAVKLVPKS---SASSLRRARWEIE 72
Query: 433 VLARVD-----NPFIVPLKFSFQSSEKLYLVLAFINGGEL--FYHLQREGRFDLSRSRFY 485
VL R+ NPF+ L SF+S E + + +GG+L H Q +G F S RFY
Sbjct: 73 VLRRLSVDSNQNPFLPRLLASFESPEYFAWAVPYCSGGDLNVLLHRQNDGVFSSSVIRFY 132
Query: 486 TAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGL------------------- 526
AE++CALE LH I YRDLKPENIL+ GH+ L DF L
Sbjct: 133 VAEIVCALEHLHTMGIAYRDLKPENILIQQSGHVTLTDFDLSRSLKKPLRPHFYQPDPEL 192
Query: 527 ------------------------------CKLNMKDQEKTT--------TFCGTPEYLA 548
++N ++ KT+ +F GT EY++
Sbjct: 193 IIDRKKSRSFSRLISPTAEKNKTGLKKTRSARVNPINRRKTSFSSGERSNSFVGTDEYVS 252
Query: 549 PELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
PE++ G G+ VDWW LGVL YEM+ G P+ + + ++ +L F D
Sbjct: 253 PEVIRGDGHDFAVDWWALGVLTYEMMYGETPFKGKSKKETFRNVLMKEPEFAGK-PNDLT 311
Query: 609 DLLIGLLCRDPKRRLGYH-GSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
DL+ LL +DP RRLG H G+ EIK FF + W L + PP+ P
Sbjct: 312 DLIRRLLVKDPNRRLGCHRGAAEIKELAFFAGVRWD-LLTEVLRPPFIP 359
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 155 bits (392), Expect = 2e-37
Identities = 95/291 (32%), Positives = 153/291 (51%), Gaps = 15/291 (5%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
I DF VIG G++ VM DT K YA K + K Y++ + +V + E+T L +++
Sbjct: 176 IKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLN 235
Query: 439 N-PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALH 497
N P +V L +FQ LY +L + G+ +++ G D + +R+Y A+++ A++ LH
Sbjct: 236 NSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLH 295
Query: 498 DFDIIYRDLKPENILLDYQGHIALCDFGLCKL------NMKDQE-----KTTTFCGTPEY 546
II+RD+KPENILLD + I L DFG KL ++ E ++ +F GT EY
Sbjct: 296 SNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEY 355
Query: 547 LAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKD 606
++PELL D W G +L++M+ G PP+ + ++K+++ F F
Sbjct: 356 VSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLI 415
Query: 607 AKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPP 657
+DL+ +L ++ RRL +IK H FF L++K + PP P
Sbjct: 416 IRDLVKKILVKNLDRRLTI---SQIKEHHFFKDLNFKDGSVWSKTPPEIKP 463
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 155 bits (392), Expect = 2e-37
Identities = 94/270 (34%), Positives = 153/270 (55%), Gaps = 13/270 (4%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARV-D 438
D + L + +G G FG + + T + A K+I K +V++ ++ E ++A++
Sbjct: 42 DRYVLGEQLGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQDDMKSIKLEIAIMAKLAG 101
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P +V LK ++ + ++LV+ GGELF+ L++ GR+ R+R L+ ++ HD
Sbjct: 102 HPNVVNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYSEVRARVLFKHLMQVVKFCHD 161
Query: 499 FDIIYRDLKPENIL---LDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
I++RDLKPENIL + I L DFGL +K EK + G+P Y+APE+L G
Sbjct: 162 SGIVHRDLKPENILMATMSSSSPIKLADFGLATY-IKPGEKLSGTVGSPFYIAPEVLAG- 219
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP----DDFDKDAKDLL 611
GY + D W+ GV+LY +L+G PP++ + K++ + LRF D+ AKDL+
Sbjct: 220 GYNQAADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNITSYAKDLI 279
Query: 612 IGLLCRDPKRRLGYHGSDEIKSHPFFNQLS 641
G+LC DP +RL +DE+ +H + QLS
Sbjct: 280 RGMLCVDPSQRL---SADEVLAHSWMEQLS 306
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 155 bits (391), Expect = 3e-37
Identities = 90/281 (32%), Positives = 154/281 (54%), Gaps = 17/281 (6%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ I DF + +G GS+ V+ RD+ K YA+K + K Y++ + +V + E+ L +
Sbjct: 120 MGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQK 179
Query: 437 VDNPF-IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
++ I L F+FQ LY +L + G+ +++ G + + +R+Y ++++ A+++
Sbjct: 180 LNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDS 239
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKL------NMKDQE-------KTTTFCG 542
LH+ II+RD+KPENILLD + L DFG K+ N D + K+ +F G
Sbjct: 240 LHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVG 299
Query: 543 TPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD 602
T EY++PELL D W G +LY+ML G PP+ + ++K+++ F
Sbjct: 300 TAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAG 359
Query: 603 FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWK 643
F + KDL+ LL RDP RL +IK+H FF++++++
Sbjct: 360 FPQIVKDLVKKLLVRDPNDRLTI---KQIKAHLFFHEVNFE 397
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 155 bits (391), Expect = 3e-37
Identities = 93/273 (34%), Positives = 148/273 (54%), Gaps = 7/273 (2%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-E 430
S + +++DF++ + +GKG FG V R++ + I ALK + K+ + K+ V H L E
Sbjct: 123 SKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQL-EKAGVEHQLRRE 181
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+ + + +P I+ L F + ++YL+L + G ++ LQ+ +FD R+ Y EL
Sbjct: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
AL H +I+RD+KPEN+LL G + + DFG + TT CGT +YL PE
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV--HAPSSRRTTLCGTLDYLPPE 299
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
++ G+ + + VD W+LGVL YE L G PP+ + YK+I + FPD + A+DL
Sbjct: 300 MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDL 359
Query: 611 LIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWK 643
+ LL +P +R E+ HP+ S K
Sbjct: 360 ISRLLKHNPSQRPMLR---EVLEHPWITANSSK 389
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 155 bits (391), Expect = 3e-37
Identities = 93/349 (26%), Positives = 170/349 (48%), Gaps = 54/349 (15%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD- 438
+DF L+ +G+G++ +V + R+ T+ ++A+K ++KSY+ ++ + E+ +L +
Sbjct: 67 NDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQ 126
Query: 439 ----NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALE 494
+PF+ L F ++Y V+ + G+L L G FD+ S+F+ +E+L L+
Sbjct: 127 ECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQ 186
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLC--------------------------- 527
LHD I++RD+KP+N+L+ GHI + DFG
Sbjct: 187 FLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSG 246
Query: 528 -----------KLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTG 576
++ ++ + TTF GT Y++PE+L D W LG +L++ L G
Sbjct: 247 SPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAG 306
Query: 577 LPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPF 636
PP+ + + K+I + FP+ F ++A +++ +L RDP R+ S E+ +H F
Sbjct: 307 QPPFRAVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPSTRI---TSQELMAHKF 363
Query: 637 FNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQE--FTREQPVDSVVND 683
F + W I KPPV+ A + F + ++ PV+ ++D
Sbjct: 364 FENVDWVN------IANIKPPVLHAYIPATFGEPEYYSNIGPVEPGLDD 406
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 154 bits (390), Expect = 3e-37
Identities = 94/279 (33%), Positives = 146/279 (51%), Gaps = 11/279 (3%)
Query: 376 HLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLA 435
HL I +F + + IGKG+FG V + T A+K + + + V T E L
Sbjct: 18 HLKIGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQ 77
Query: 436 RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
++ +P I L + ++LV+ ++GGELF ++ R+G + SR Y +++ +
Sbjct: 78 KLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSY 137
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
H+ I++RDLKPEN+LLD +I + DFGL M D + +T CG+P Y APEL+ +
Sbjct: 138 CHNHMIVHRDLKPENLLLDANKNIKIADFGLSNY-MTDGDLLSTACGSPNYAAPELISNK 196
Query: 556 GYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGL 614
Y VD W+ GV+LY ML G P+ D++VP ++ KI P +K A DL+ +
Sbjct: 197 LYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTM 256
Query: 615 LCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
L DP +R I +H SW R+ + Y+ P
Sbjct: 257 LQVDPVKRADV---KRIVNH------SWFRIDLPYYLFP 286
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 154 bits (389), Expect = 5e-37
Identities = 85/264 (32%), Positives = 151/264 (57%), Gaps = 7/264 (2%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERT-VLA 435
+ ++D+ +++++G+GSFG+V + R++ T + A+K I K K H+L + +L
Sbjct: 1 MGVEDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKD--IHSLRQEIEILR 58
Query: 436 RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
++ + I+ + SF+++ + +V F G ELF L+ + + + +L+ AL+
Sbjct: 59 KLKHENIIEMLDSFENAREFCVVTEFAQG-ELFEILEDDKCLPEEQVQAIAKQLVKALDY 117
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
LH II+RD+KP+NIL+ + LCDFG + + + GTP Y+APEL+ Q
Sbjct: 118 LHSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVKEQ 177
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y + VD W+LGV+LYE+ G PP+Y V + + I++DP+++PD+ + L GLL
Sbjct: 178 PYDRTVDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKDPVKYPDEMSTYFESFLKGLL 237
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQ 639
++P RL + ++ HPF +
Sbjct: 238 NKEPHSRLTW---PALREHPFVKE 258
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 153 bits (387), Expect = 8e-37
Identities = 100/329 (30%), Positives = 166/329 (50%), Gaps = 26/329 (7%)
Query: 372 STHKHLSI-DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
+T+K +SI ++ + K +G GSF KV T A+K + +S I + E
Sbjct: 8 TTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQRE 67
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+L + +P I+ ++ +Y+V+ ++ GELF ++ +G+ +R +++
Sbjct: 68 IKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQII 127
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
+E H I++RDLKPEN+LLD Q +I + DFGL + M D T CG+P Y APE
Sbjct: 128 SGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNV-MHDGHFLKTSCGSPNYAAPE 186
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
++ G+ Y VD W+ GV+LY +L G P+ DE++P +++KI + P+ A+DL
Sbjct: 187 VISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDL 246
Query: 611 LIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYK--PPVMGAMDTSNFD 668
+ +L DP R+ EI+ HP+FN ++P Y PP+ +
Sbjct: 247 IPRMLMVDPTMRISI---TEIRQHPWFN----------NHLPLYLSIPPLDTIDQAKKIE 293
Query: 669 QE---------FTREQPVDSVVNDFLSES 688
+E F R VDS+ N +E+
Sbjct: 294 EEIIQNVVNIGFDRNHVVDSLANRIQNEA 322
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 153 bits (387), Expect = 8e-37
Identities = 92/271 (33%), Positives = 150/271 (54%), Gaps = 10/271 (3%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-E 430
+ K ++ DFD+ K +G+G FG V R++ +N + ALK + KS + +S+V H L E
Sbjct: 21 AAQKRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQL-QQSQVEHQLRRE 79
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+ + + +P I+ L F +++YL+L + GEL+ LQ+ F R+ Y A L
Sbjct: 80 VEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLA 139
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
AL H +I+RD+KPEN+L+ QG + + DFG ++ + T CGT +YL PE
Sbjct: 140 RALIYCHGKHVIHRDIKPENLLIGAQGELKIADFG---WSVHTFNRRRTMCGTLDYLPPE 196
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD--FDKDAK 608
++ + VD W+LG+L YE L G+PP+ + Y++I+Q L+FP AK
Sbjct: 197 MVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAK 256
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQ 639
DL+ +L ++ +RL H ++ HP+ Q
Sbjct: 257 DLISQMLVKESSQRLPLH---KLLEHPWIVQ 284
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 153 bits (386), Expect = 1e-36
Identities = 87/261 (33%), Positives = 142/261 (54%), Gaps = 7/261 (2%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
++L +++G G+F KV R T K A+K + K +V V E +V+ V +P
Sbjct: 24 YELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPN 83
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
IV L S K+Y + + GGELF + + GR +R Y +L+ A++ H +
Sbjct: 84 IVELHEVMASKSKIYFAMELVRGGELFAKVAK-GRLREDVARVYFQQLISAVDFCHSRGV 142
Query: 502 IYRDLKPENILLDYQGHIALCDFGLCKL--NMKDQEKTTTFCGTPEYLAPELLLGQGYTK 559
+RDLKPEN+LLD +G++ + DFGL ++K T CGTP Y+APE++L +GY
Sbjct: 143 YHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDG 202
Query: 560 V-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
D W+ GV+L+ +L G P+ D+++ MY+KI + + P DA+ L+ LL +
Sbjct: 203 AKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRLVTKLLDPN 262
Query: 619 PKRRLGYHGSDEIKSHPFFNQ 639
P R+ +++ P+F +
Sbjct: 263 PNTRITI---EKVMDSPWFKK 280
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 152 bits (385), Expect = 1e-36
Identities = 92/271 (33%), Positives = 150/271 (54%), Gaps = 10/271 (3%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-E 430
+ K + DFD+ K +G+G FG V R++ ++ I ALK + K+ + +S+V H L E
Sbjct: 9 AAQKRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQL-QQSQVEHQLRRE 67
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+ + + +P I+ L F +++YL+L + GEL+ LQ+ F R+ Y A L
Sbjct: 68 VEIQSHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLA 127
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPE 550
AL H +I+RD+KPEN+L+ QG + + DFG ++ + T CGT +YL PE
Sbjct: 128 RALIYCHGKHVIHRDIKPENLLIGAQGELKIADFG---WSVHTFNRRRTMCGTLDYLPPE 184
Query: 551 LLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD--FDKDAK 608
++ + VD W+LG+L YE L G+PP+ + + YK+I+Q L+FP AK
Sbjct: 185 MVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAK 244
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQ 639
DL+ +L ++ +RL H ++ HP+ Q
Sbjct: 245 DLISQMLVKESTQRLALH---KLLEHPWIVQ 272
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 152 bits (384), Expect = 2e-36
Identities = 82/245 (33%), Positives = 140/245 (56%), Gaps = 4/245 (1%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
+++ +++GKG+FGKV ++ T + A+K I K + + + E +++ V +P
Sbjct: 15 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVRHPN 74
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
IV LK + K++ ++ ++ GGELF + + G+ +R Y +L+ A++ H +
Sbjct: 75 IVELKEVMATKTKIFFIMEYVKGGELFSKIVK-GKLKEDSARKYFQQLISAVDFCHSRGV 133
Query: 502 IYRDLKPENILLDYQGHIALCDFGLCKL--NMKDQEKTTTFCGTPEYLAPELLLGQGYTK 559
+RDLKPEN+L+D G + + DFGL L + T CGTP Y+APE+L +GY
Sbjct: 134 SHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYDG 193
Query: 560 VV-DWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
D W+ G++LY +L G P+ DE++ KMY+KI + +P F ++K L+ LL D
Sbjct: 194 AKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPWFSPESKRLISKLLVVD 253
Query: 619 PKRRL 623
P +R+
Sbjct: 254 PNKRI 258
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 152 bits (383), Expect = 2e-36
Identities = 94/308 (30%), Positives = 151/308 (48%), Gaps = 26/308 (8%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ +++ + IG+G+F KV R +T + ALK + K ++ E + +
Sbjct: 11 VGKYEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIK 70
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P +V L S K++++L ++ GGELF + +GR +R Y +L+ A++ H
Sbjct: 71 HPNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHS 130
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLN--MKDQEKTTTFCGTPEYLAPELLLGQG 556
+ +RDLKPEN+LLD G++ + DFGL L+ ++D T CGTP Y+APE+L +G
Sbjct: 131 RGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRG 190
Query: 557 YT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y D W+ GV+LY +L G P+ D ++ +YKKI P A L+ +L
Sbjct: 191 YDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFNCPPWLSLGAMKLITRIL 250
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTREQ 675
+P R+ E+ +F + YKPPV D SN D
Sbjct: 251 DPNPMTRV---TPQEVFEDEWFKK-------------DYKPPVFEERDDSNMDD------ 288
Query: 676 PVDSVVND 683
+D+V D
Sbjct: 289 -IDAVFKD 295
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 151 bits (382), Expect = 3e-36
Identities = 94/300 (31%), Positives = 151/300 (50%), Gaps = 18/300 (6%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
ST + DF +++G+GS+ V+ + T + YA+K + K +I+ + + + E+
Sbjct: 89 STPNIKRVSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEK 148
Query: 432 TVLARVD-NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
L + +P + L ++FQ + LY VL+ GEL ++ + GRF+ +++Y A ++
Sbjct: 149 EALCILSKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIV 208
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCK-LNM-------------KDQEK 536
+++ +H +I+RDLKPENILLD + DFG K LN K Q
Sbjct: 209 DSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAH 268
Query: 537 TTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDP 596
+ +F GT Y++PE+L + D W G +L++ML G PP+ + ++ IL
Sbjct: 269 SRSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLS 328
Query: 597 LRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKP 656
P D A DL+ LL DPK RL DEI HPFFN + + + P KP
Sbjct: 329 YEIPPDISDVASDLIKKLLVLDPKDRLTV---DEIHQHPFFNGIKFDNTLWELPPPRLKP 385
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 151 bits (382), Expect = 3e-36
Identities = 91/299 (30%), Positives = 153/299 (50%), Gaps = 17/299 (5%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ ++ L + +G GSFG+V T A+K + + I + E +L
Sbjct: 16 LPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 75
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P I+ L ++ +YLV+ ++N GELF ++ +GR +R + +++ +E H
Sbjct: 76 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 135
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+++RDLKPEN+LLD + ++ + DFGL + M+D T CG+P Y APE++ G+ Y
Sbjct: 136 NMVVHRDLKPENLLLDSKCNVKIADFGLSNI-MRDGHFLKTSCGSPNYAAPEVISGKLYA 194
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+ GV+LY +L G P+ DE++P ++KKI P A+DL+ +L
Sbjct: 195 GPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVV 254
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPY--KPPVMGAMDTSNFDQEFTRE 674
DP +R+ EI+ HP+F + ++P Y PP D+E +E
Sbjct: 255 DPMKRVTI---PEIRQHPWF----------QAHLPRYLAVPPPDTVQQAKKIDEEILQE 300
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 151 bits (381), Expect = 4e-36
Identities = 95/297 (31%), Positives = 155/297 (51%), Gaps = 21/297 (7%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTVLARVDNP 440
+++ +++GKG+F KV ++ + A+K I K ++ + + + E +++ V +P
Sbjct: 12 YEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHP 71
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
IV LK + K++ V+ F+ GGELF + + G+ +R Y +L+ A++ H
Sbjct: 72 NIVELKEVMATKTKIFFVMEFVKGGELFCKISK-GKLHEDAARRYFQQLISAVDYCHSRG 130
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCKL--NMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+ +RDLKPEN+LLD G + + DFGL L + T CGTP Y+APE+L +GY
Sbjct: 131 VSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYD 190
Query: 559 KV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
D W+ GV+LY +L G P+ DE++ MY+KI + FP F +A+ L+ LL
Sbjct: 191 GAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPWFSPEARRLISKLLVV 250
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP----YKPPVMGAMDTSNFDQE 670
DP RR+ S P + W R K + PP P+ +N ++E
Sbjct: 251 DPDRRI---------SIPAIMRTPWLR---KNFTPPLAFKIDEPICSQSSKNNEEEE 295
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 150 bits (380), Expect = 5e-36
Identities = 89/264 (33%), Positives = 145/264 (54%), Gaps = 7/264 (2%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+D +++ K++G GSF KV R + + A+K I K IV H E ++L RV
Sbjct: 54 MDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVR 113
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P+IV L + K+Y+V+ ++ GGEL Y+ GR +R Y +L+ ++ H
Sbjct: 114 HPYIVHLLEVMATKTKIYIVMEYVRGGEL-YNTVARGRLREGTARRYFQQLISSVAFCHS 172
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLN--MKDQEKTTTFCGTPEYLAPELLLGQG 556
+ +RDLK EN+LLD +G++ + DFGL ++ +K + TFCGTP YLAPE+L +G
Sbjct: 173 RGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKG 232
Query: 557 YTKV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y D W+ GV+L+ ++ G P+ D+++ MY KI + + P F + L+ +L
Sbjct: 233 YEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPELARLVTRML 292
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQ 639
+P R+ EI H +F +
Sbjct: 293 DTNPDTRITI---PEIMKHRWFKK 313
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 150 bits (379), Expect = 7e-36
Identities = 99/300 (33%), Positives = 155/300 (51%), Gaps = 33/300 (11%)
Query: 373 THKHLSIDDFDLLKVIGKGSFGKVMQ-VRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
T + S DF + +G GS+ V + + K+ NKIYA+K K +I+ +++V + E+
Sbjct: 2 TSRKRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEK 61
Query: 432 T---VLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAE 488
+LA+ + I+ L ++F E LY VL F GGEL L + G F+ +R +TA+
Sbjct: 62 NTMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQ 121
Query: 489 LLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGL------------CKLN-----M 531
L+ ALE +H II+RDLKPEN+LLD G + + DFG K N
Sbjct: 122 LIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGS 181
Query: 532 KDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKK 591
KD + +F GT EY++PELLL D W LG ++Y+ + G PP+ E+ K ++K
Sbjct: 182 KDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEK 241
Query: 592 ILQ-----DPLRFPDDFDKDAKDLLIGL----LCRDPKRRLGYHGSDEIKSHPFFNQLSW 642
I+ P ++ L+I L L + R+ ++IK HP+F+++ W
Sbjct: 242 IVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISL---EQIKRHPYFSKVDW 298
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 149 bits (377), Expect = 1e-35
Identities = 86/245 (35%), Positives = 130/245 (52%), Gaps = 4/245 (1%)
Query: 381 DFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNP 440
DF++ +G+G FG+V R+R ++ + A+K + K + L E + +R+ +P
Sbjct: 52 DFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHP 111
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQR--EGRFDLSRSRFYTAELLCALEALHD 498
I+ L F ++YL L + GELF HL+ RFD RS YT ++ AL H
Sbjct: 112 HILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHL 171
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
++I+RDLKPENILL + L DFG ++ +T CGT +YL PE++ G Y
Sbjct: 172 NNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRT--LCGTLDYLPPEMVDGNSYD 229
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
VD W LG+L YE + G PP+ Y KI + + +P K K+L+ GLL ++
Sbjct: 230 DSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLRKE 289
Query: 619 PKRRL 623
K R+
Sbjct: 290 SKGRI 294
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 149 bits (375), Expect = 2e-35
Identities = 89/255 (34%), Positives = 135/255 (52%), Gaps = 8/255 (3%)
Query: 388 IGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLKF 447
IG+G F + +V+ N IYA K I K + + E V + +P IV
Sbjct: 47 IGEGGFARCFRVKDNYGN-IYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGFID 105
Query: 448 SFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLK 507
F+ S +YL+L L L++ + R+ ++L AL+ +H +I+RDLK
Sbjct: 106 CFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRDLK 165
Query: 508 PENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG--QGYTKVVDWWT 565
NI+LD ++ + DFGL L M D+E+ T CGTP Y+APE+L +G++ VD W+
Sbjct: 166 LGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVDLWS 225
Query: 566 LGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPD--DFDKDAKDLLIGLLCRDPKRRL 623
GV++Y +L G PP+ D++V +Y+KI + FP D +AKDL+ LL DP R
Sbjct: 226 AGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDPSIR- 284
Query: 624 GYHGSDEIKSHPFFN 638
D+I H FF+
Sbjct: 285 --PSIDDIVDHEFFH 297
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 149 bits (375), Expect = 2e-35
Identities = 78/248 (31%), Positives = 131/248 (52%), Gaps = 1/248 (0%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ ++L + +G+G+F KV R + A+K I K ++ + E + + +
Sbjct: 28 VGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIK 87
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P ++ + S K+Y VL F+ GGELF + GR +R Y +L+ A++ H
Sbjct: 88 HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHS 147
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+ +RDLKPEN+LLD G + + DFGL L ++ T CGTP Y+APE++ +GY
Sbjct: 148 RGVYHRDLKPENLLLDANGALKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVINNKGYD 207
Query: 559 KV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
D W+ GV+L+ ++ G P+ D ++ +YKKI + P F AK L+ +L
Sbjct: 208 GAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFSASAKKLIKRILDP 267
Query: 618 DPKRRLGY 625
+P R+ +
Sbjct: 268 NPATRITF 275
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 148 bits (374), Expect = 2e-35
Identities = 102/291 (35%), Positives = 152/291 (52%), Gaps = 28/291 (9%)
Query: 381 DFDLLKVIGKGSFGKVMQVR----KRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
D+ + K +G+GSF V R K D N ALK K I+ V + E+ LA
Sbjct: 25 DYSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALAL 84
Query: 437 VD-----NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQRE--GRFDLSRSRFYTAEL 489
+ +P IV L +FQ SE LY VL + G+L +Q++ +F+++ SR+Y A L
Sbjct: 85 ISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADSRYYAANL 144
Query: 490 LCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKL---------NMKDQEKTT-- 538
L ALE +H II+RD+K +N+L+ G I L DFG K N ++E+ T
Sbjct: 145 LSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQENPVEEEQPTGR 204
Query: 539 --TFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDP 596
+F GT ++ PELL G + D W V LY LTG+ P+ D ++++I
Sbjct: 205 RSSFVGTAFFVTPELLTGSEMSPSSDLWAFSVTLYLFLTGIYPFNDMSEYLVFRRIQDIL 264
Query: 597 LRFPDDF-DKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLK 646
F +DF D++AK+L+ LL ++ K RL S EIK H FF + ++ L+
Sbjct: 265 YTFSEDFPDENAKNLIERLLVKEQKSRL---TSQEIKEHKFFESIDFEHLE 312
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 147 bits (372), Expect = 4e-35
Identities = 80/260 (30%), Positives = 149/260 (56%), Gaps = 6/260 (2%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ + L K +GKG G V T + A+K + + + S+S + E +L ++
Sbjct: 48 VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKL-SESVLMKVEREIAILKLIE 106
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P ++ L +++ + LYLVL ++GGELF +L ++GR +R + +++ AL+ H
Sbjct: 107 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 166
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+ I +RDLKPEN+LLD + +I + DFG+ L + D T+ CG+P Y PE++ G+ Y
Sbjct: 167 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS-CGSPHYACPEVIKGEKYD 225
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
+ D W+ GV+L+ +L G P+ D+++ ++ +K+ + P D + LL G++
Sbjct: 226 GRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEV 285
Query: 618 DPKRRLGYHGSDEIKSHPFF 637
+P++RL ++I+ HP++
Sbjct: 286 EPEKRLSL---EQIQKHPWY 302
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 147 bits (372), Expect = 4e-35
Identities = 93/281 (33%), Positives = 154/281 (54%), Gaps = 7/281 (2%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ + LLK IGKG+F KV + T A+K I K+ + + S + E ++ ++D
Sbjct: 119 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTAL-NPSSLQKLFREVKIMKQLD 177
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P IV L ++ + LYLVL + +GGE+F +L GR +R +++ A++ LH
Sbjct: 178 HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHS 237
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+II+RDLK EN+LLD +I + DFG K TFCG+P Y APEL G+ Y
Sbjct: 238 KNIIHRDLKAENLLLDQDMNIKIADFGFSN-TFSLGNKLDTFCGSPPYAAPELFSGKKYD 296
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+LGV+LY +++G P+ +++ ++ +++L+ R P D ++LL L
Sbjct: 297 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVI 356
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV 658
+P+RR D I + N + ++ ++K +I P K +
Sbjct: 357 NPQRR---SSLDNIMKDRWMN-VGYEDDELKPFIEPPKDQI 393
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 147 bits (372), Expect = 4e-35
Identities = 93/281 (33%), Positives = 154/281 (54%), Gaps = 7/281 (2%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ + LLK IGKG+F KV + T A+K I K+ + + S + E ++ ++D
Sbjct: 167 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTAL-NPSSLQKLFREVKIMKQLD 225
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P IV L ++ + LYLVL + +GGE+F +L GR +R +++ A++ LH
Sbjct: 226 HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHS 285
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+II+RDLK EN+LLD +I + DFG K TFCG+P Y APEL G+ Y
Sbjct: 286 KNIIHRDLKAENLLLDQDMNIKIADFGFSN-TFSLGNKLDTFCGSPPYAAPELFSGKKYD 344
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+LGV+LY +++G P+ +++ ++ +++L+ R P D ++LL L
Sbjct: 345 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVI 404
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPV 658
+P+RR D I + N + ++ ++K +I P K +
Sbjct: 405 NPQRR---SSLDNIMKDRWMN-VGYEDDELKPFIEPPKDQI 441
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 147 bits (371), Expect = 6e-35
Identities = 89/268 (33%), Positives = 145/268 (53%), Gaps = 7/268 (2%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTVLA 435
++++DF++ + +GKG FG V R++ + I ALK + K+ + K+ V H L E + +
Sbjct: 127 VALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQL-EKAGVEHQLRREVEIQS 185
Query: 436 RVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEA 495
+ +P I+ L F + ++YL+L + G ++ LQ+ +FD R+ + AL
Sbjct: 186 HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANALSY 245
Query: 496 LHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
H +I+RD+KPEN+LL G + + DFG + TT CGT +YL PE++ G+
Sbjct: 246 CHSKRVIHRDIKPENLLLGSAGELKIADFGWSV--HAPSSRRTTLCGTLDYLPPEMIEGR 303
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
+ + VD W+LGVL YE L G PP+ + YK+I + FPD + A+DL+ LL
Sbjct: 304 MHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 363
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQLSWK 643
+P +R E+ HP+ S K
Sbjct: 364 KHNPSQRPMLR---EVLEHPWITANSSK 388
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 147 bits (371), Expect = 6e-35
Identities = 80/250 (32%), Positives = 143/250 (57%), Gaps = 3/250 (1%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
HKH ++L + +GKG++GKV + +R + ++ A+K+IRK I + ++ H E +
Sbjct: 47 HKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEI 106
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
++ +++P I+ + F++ +K+ +++ + + GEL+ ++ R +R + +++ A+
Sbjct: 107 MSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAV 166
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLL 553
H +++RDLK ENILLD +I + DFGL L KD + TFCG+P Y +PE++
Sbjct: 167 HYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD-KFLQTFCGSPLYASPEIVN 225
Query: 554 GQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLI 612
G+ Y VD W LGVLLY ++ G P+ D + ++I R P DA+ L+
Sbjct: 226 GRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIR 284
Query: 613 GLLCRDPKRR 622
+L +P RR
Sbjct: 285 WMLMVNPDRR 294
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 147 bits (371), Expect = 6e-35
Identities = 90/267 (33%), Positives = 140/267 (51%), Gaps = 15/267 (5%)
Query: 380 DDFDLLKVIGKGSFGKVMQVR-KRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ +D V+G G+F KV K D ++YA+K I K + K E E VL ++
Sbjct: 20 EKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLEN--EIKVLRKLR 77
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+ IV L ++ + +YLV+ + GGELF + +G + + ++L A+ +HD
Sbjct: 78 HNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHD 137
Query: 499 FDIIYRDLKPENILL---DYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
+++RDLKPEN+L D I + DFGL K +D T CGTP Y+APE+L +
Sbjct: 138 NGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKT--EDSGVMATACGTPGYVAPEVLQQK 195
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP----DDFDKDAKDLL 611
Y K VD W++GV+ Y +L G PP+YDE ++ +I++ F D AKD +
Sbjct: 196 PYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFI 255
Query: 612 IGLLCRDPKRRLGYHGSDEIKSHPFFN 638
L+C DP+ R + SHP+ +
Sbjct: 256 THLMCCDPEARF---TCQDALSHPWIS 279
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 147 bits (371), Expect = 6e-35
Identities = 77/215 (35%), Positives = 127/215 (58%), Gaps = 10/215 (4%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
+++L V+GKGSF +V++V+ R T K +A+K + +E+ +L+R+ +PF
Sbjct: 71 YEVLAVVGKGSFSQVLRVQHRVTRKYFAVKVVNGDCGAVNNELN-------ILSRLSHPF 123
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
++ L+ F+SS KL++V+ +GGE++ + +GR+ +R LL L LH +
Sbjct: 124 VIRLEEVFKSSSKLFIVMQMASGGEMYDRVVAKGRYSEEEARNALKMLLTGLTYLHSIRV 183
Query: 502 IYRDLKPENILLDY---QGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+RDLKPEN+L + + + DFGL K E T CGTPEY+APELLL YT
Sbjct: 184 THRDLKPENLLYADSRPEARLLITDFGLAYQATKPNETMTETCGTPEYIAPELLLRVPYT 243
Query: 559 KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL 593
+ VD W +GV+ Y +++G+ P+ D+ ++Y I+
Sbjct: 244 QKVDMWAVGVIAYILMSGIMPFDDDCRSRLYTHII 278
>Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 147
Score = 146 bits (369), Expect = 9e-35
Identities = 73/140 (52%), Positives = 97/140 (69%)
Query: 423 EVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRS 482
+ HT AE +L V +PFIV L ++FQ+ KLYL+L +++GGELF L+REG F +
Sbjct: 8 DTAHTKAEWNILEEVRHPFIVDLTYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTA 67
Query: 483 RFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCG 542
FY AE+ AL LH IIYRDLKPENI+L++QGH+ L DFGL K ++ D T TFCG
Sbjct: 68 CFYLAEISMALGHLHQKGIIYRDLKPENIILNHQGHMKLTDFGLRKESIHDGTVTHTFCG 127
Query: 543 TPEYLAPELLLGQGYTKVVD 562
T EY+APE+L+ G+ + VD
Sbjct: 128 TIEYMAPEILMRSGHNRAVD 147
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 146 bits (369), Expect = 9e-35
Identities = 90/299 (30%), Positives = 153/299 (51%), Gaps = 15/299 (5%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ I + L + +G G+FGKV T A+K + + I S V E L+
Sbjct: 20 IKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSL 79
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+P I+ L + +++++ ++GGELF ++ + GR + +R + +++ ++
Sbjct: 80 FRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYC 139
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +++RDLKPEN+LLD Q ++ + DFGL + M D + T CG+P Y APE++ G+
Sbjct: 140 HRHMVVHRDLKPENLLLDEQNNVKIADFGLSNI-MTDGDFLRTSCGSPNYAAPEVISGKL 198
Query: 557 YT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y VD W+ GV+LY +L G P+ DE VP +++KI PD ++ +LL +L
Sbjct: 199 YAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHML 258
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
C DP +R ++ +H +F + +P Y P + + S D E RE
Sbjct: 259 CVDPMKRATI---KDVIAHEWFQK----------DLPNYLFPPINESEASIVDIEAVRE 304
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 146 bits (369), Expect = 9e-35
Identities = 90/299 (30%), Positives = 153/299 (51%), Gaps = 15/299 (5%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ I + L + +G G+FGKV T A+K + + I S V E L+
Sbjct: 20 IKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSL 79
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+P I+ L + +++++ ++GGELF ++ + GR + +R + +++ ++
Sbjct: 80 FRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYC 139
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +++RDLKPEN+LLD Q ++ + DFGL + M D + T CG+P Y APE++ G+
Sbjct: 140 HRHMVVHRDLKPENLLLDEQNNVKIADFGLSNI-MTDGDFLRTSCGSPNYAAPEVISGKL 198
Query: 557 YT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y VD W+ GV+LY +L G P+ DE VP +++KI PD ++ +LL +L
Sbjct: 199 YAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHML 258
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
C DP +R ++ +H +F + +P Y P + + S D E RE
Sbjct: 259 CVDPMKRATI---KDVIAHEWFQK----------DLPNYLFPPINESEASIVDIEAVRE 304
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 146 bits (369), Expect = 9e-35
Identities = 85/250 (34%), Positives = 134/250 (53%), Gaps = 5/250 (2%)
Query: 387 VIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPLK 446
++G+GSFG V + ++D +K+ A+K I K +K E+ + E + AR+ +P ++ +
Sbjct: 9 MVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATK-ELKNLRRECDIQARLKHPHVIEMI 67
Query: 447 FSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDL 506
SF+S L++V F +L +L G +R T L+ AL LH I++RDL
Sbjct: 68 ESFESKTDLFVVTEFALM-DLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDL 126
Query: 507 KPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTL 566
KP+N+LLD H LCDFGL + T+ GTP Y+APELL Q Y D W+L
Sbjct: 127 KPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSL 186
Query: 567 GVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYH 626
G + YE + G PP+ + + K I + +++P + + L GLL +DP R+ +
Sbjct: 187 GCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSECRSFLQGLLEKDPGLRISW- 245
Query: 627 GSDEIKSHPF 636
++ HPF
Sbjct: 246 --TQLLCHPF 253
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 145 bits (367), Expect = 2e-34
Identities = 81/245 (33%), Positives = 137/245 (55%), Gaps = 4/245 (1%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
++L +++G+G+F KV R T + A+K I K + + E +V+ V +P
Sbjct: 12 YELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPH 71
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
+V L S K+Y + ++ GGELF + + G+ + +R Y +L+ A++ H +
Sbjct: 72 VVFLHEVMASKTKIYFAMEYVKGGELFDKVSK-GKLKENIARKYFQQLIGAIDYCHSRGV 130
Query: 502 IYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEK--TTTFCGTPEYLAPELLLGQGYTK 559
+RDLKPEN+LLD G + + DFGL L Q+ T CGTP Y+APE++ +GY
Sbjct: 131 YHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDG 190
Query: 560 V-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRD 618
D W+ GV+LY +L G P++++++ +MY+KI + + P+ F + K LL +L +
Sbjct: 191 AKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKLLSRILDPN 250
Query: 619 PKRRL 623
P R+
Sbjct: 251 PNSRI 255
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 145 bits (367), Expect = 2e-34
Identities = 86/246 (34%), Positives = 133/246 (53%), Gaps = 4/246 (1%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN-P 440
++L + +G GSF KV R T ++ A+K I K + + E + R+ N P
Sbjct: 21 YELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLHNHP 80
Query: 441 FIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFD 500
++ + + K+YLV+ + GGELF L R GR + S +R Y +L AL H
Sbjct: 81 NVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCHRDG 140
Query: 501 IIYRDLKPENILLDYQGHIALCDFGLCKL--NMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I +RD+KP+N+LLD QG++ + DFGL L + + T CGTP Y APE++ +GY
Sbjct: 141 IAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHRSNNGLLHTACGTPAYTAPEVIAQRGYD 200
Query: 559 KV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
D W+ GV L+ +L G P+ D ++ MY+KI + RFP K A+ ++ LL
Sbjct: 201 GAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYRFPSWISKPARSIIYKLLDP 260
Query: 618 DPKRRL 623
+P+ R+
Sbjct: 261 NPETRM 266
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 145 bits (365), Expect = 3e-34
Identities = 87/267 (32%), Positives = 152/267 (56%), Gaps = 9/267 (3%)
Query: 374 HKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV 433
HKH ++ L+ +GKG++GKV + R+ + ++ A+K+IRK I + ++ H E +
Sbjct: 45 HKHNLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEI 103
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
++ +++P I+ + F++S K+ +V+ + + G+L+ ++ + +R + +++ A+
Sbjct: 104 MSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAV 163
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEK-TTTFCGTPEYLAPELL 552
H +++RDLK ENILLD G+I + DFGL N+ Q K TFCG+P Y +PE++
Sbjct: 164 HYCHQNRVVHRDLKLENILLDANGNIKIADFGLS--NLYHQGKFLQTFCGSPLYASPEIV 221
Query: 553 LGQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLL 611
G+ YT VD W+LGVLLY ++ G P+ D + K+I R P DA L+
Sbjct: 222 NGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPK-PSDACGLI 280
Query: 612 IGLLCRDPKRRLGYHGSDEIKSHPFFN 638
LL +P RR +++ SH + N
Sbjct: 281 RWLLMVNPTRRATL---EDVASHWWVN 304
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 145 bits (365), Expect = 3e-34
Identities = 84/264 (31%), Positives = 142/264 (52%), Gaps = 5/264 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ I + L +G G+FGKV + T A+K + + I S V E L
Sbjct: 23 VKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKL 82
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+P I+ L + +++++ +++GGELF ++ + G+ ++R + +++ ++
Sbjct: 83 FRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYC 142
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H I++RDLKPEN+LLD+ H+ + DFGL + M D E T CG+P Y APE++ G+
Sbjct: 143 HRHMIVHRDLKPENLLLDHNMHVKIADFGLSNM-MLDGEFLRTSCGSPNYAAPEVISGKL 201
Query: 557 YT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y VD W+ GV+LY +L G P+ DE VP +++KI P+ +K +L+ +L
Sbjct: 202 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQML 261
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQ 639
DP +R +EIK H +F +
Sbjct: 262 QVDPLKRANI---EEIKKHEWFQK 282
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 144 bits (364), Expect = 4e-34
Identities = 101/313 (32%), Positives = 165/313 (52%), Gaps = 13/313 (4%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
I ++ LLK IGKG+F KV R T K A+K I K+ + S S + E ++ ++
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS-LQKLFREVRIMKVLN 75
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P IV L ++ + LYLV+ + +GGE+F +L GR +R +++ A++ H
Sbjct: 76 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 135
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I++RDLK EN+LLD +I + DFG K TFCG+P Y APEL G+ Y
Sbjct: 136 KFIVHRDLKAENLLLDADMNIKIADFGFSN-EFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+LGV+LY +++G P+ +++ ++ +++L+ R P D ++LL L
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 254
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYI---PPYKPPVMGAMDTSNFDQEFTRE 674
+P +R G+ E + + + ++K Y+ P YK P + S +TRE
Sbjct: 255 NPSKR----GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVS---MGYTRE 307
Query: 675 QPVDSVVNDFLSE 687
+ DS+V +E
Sbjct: 308 EIQDSLVGQRYNE 320
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 144 bits (364), Expect = 4e-34
Identities = 101/313 (32%), Positives = 165/313 (52%), Gaps = 13/313 (4%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
I ++ LLK IGKG+F KV R T K A+K I K+ + S S + E ++ ++
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS-LQKLFREVRIMKVLN 75
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P IV L ++ + LYLV+ + +GGE+F +L GR +R +++ A++ H
Sbjct: 76 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 135
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I++RDLK EN+LLD +I + DFG K TFCG+P Y APEL G+ Y
Sbjct: 136 KFIVHRDLKAENLLLDADMNIKIADFGFSN-EFTFGNKLDTFCGSPPYAAPELFQGKKYD 194
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+LGV+LY +++G P+ +++ ++ +++L+ R P D ++LL L
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 254
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYI---PPYKPPVMGAMDTSNFDQEFTRE 674
+P +R G+ E + + + ++K Y+ P YK P + S +TRE
Sbjct: 255 NPSKR----GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVS---MGYTRE 307
Query: 675 QPVDSVVNDFLSE 687
+ DS+V +E
Sbjct: 308 EIQDSLVGQRYNE 320
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 144 bits (364), Expect = 4e-34
Identities = 101/313 (32%), Positives = 165/313 (52%), Gaps = 13/313 (4%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
I ++ LLK IGKG+F KV R T K A+K I K+ + S S + E ++ ++
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS-LQKLFREVRIMKVLN 108
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P IV L ++ + LYLV+ + +GGE+F +L GR +R +++ A++ H
Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 168
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I++RDLK EN+LLD +I + DFG K TFCG+P Y APEL G+ Y
Sbjct: 169 KFIVHRDLKAENLLLDADMNIKIADFGFSN-EFTFGNKLDTFCGSPPYAAPELFQGKKYD 227
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+LGV+LY +++G P+ +++ ++ +++L+ R P D ++LL L
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLIL 287
Query: 618 DPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYI---PPYKPPVMGAMDTSNFDQEFTRE 674
+P +R G+ E + + + ++K Y+ P YK P + S +TRE
Sbjct: 288 NPSKR----GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVS---MGYTRE 340
Query: 675 QPVDSVVNDFLSE 687
+ DS+V +E
Sbjct: 341 EIQDSLVGQRYNE 353
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 144 bits (364), Expect = 4e-34
Identities = 80/246 (32%), Positives = 142/246 (57%), Gaps = 3/246 (1%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
I +++ + IG+G+F KV A+K I K+ ++ K + E + ++
Sbjct: 9 IGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTMKLLN 68
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P IV + + K+ +V+ +++GG+L L R+ + S +R +L+ A++ H+
Sbjct: 69 HPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQ-KMKESDARKLFQQLIDAVDYCHN 127
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+ +RDLKP+N+LLD +G++ + DFGL + K + +T CG+P Y+APEL++ +GY+
Sbjct: 128 RGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVP-KSGDMLSTACGSPCYIAPELIMNKGYS 186
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+ GV+L+E+L G PP+ D +P +YKKIL+ FP F + K L+ +L
Sbjct: 187 GAAVDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNILDP 246
Query: 618 DPKRRL 623
+P R+
Sbjct: 247 NPLSRI 252
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 144 bits (364), Expect = 4e-34
Identities = 83/260 (31%), Positives = 140/260 (52%), Gaps = 5/260 (1%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ ++ L K +G GSFGKV T A+K + + I + E +L
Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P I+ +++ +Y+V+ ++ GELF ++ +GR +R + +++ +E H
Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 136
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
+++RDLKPEN+LLD + +I + DFGL + M+D T CG+P Y APE++ G+ Y
Sbjct: 137 NMVVHRDLKPENLLLDSRCNIKIADFGLSNV-MRDGHFLKTSCGSPNYAAPEVISGKLYA 195
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
VD W+ GV+LY +L G P+ DE++P ++KKI P +A+DL+ +L
Sbjct: 196 GPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIV 255
Query: 618 DPKRRLGYHGSDEIKSHPFF 637
DP +R+ EI+ H +F
Sbjct: 256 DPVKRITI---PEIRQHRWF 272
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 144 bits (363), Expect = 5e-34
Identities = 85/255 (33%), Positives = 137/255 (53%), Gaps = 3/255 (1%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
+T + + ++L + +G GSF KV R +++++ A+K I K + + E
Sbjct: 15 TTPAKILLGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEPRIIREI 74
Query: 432 TVLARV-DNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+ R+ +P I+ + + K+YLV+ +GGELF + R GR S +R Y +L
Sbjct: 75 DAMRRLRHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARRYFQQLA 134
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTT-TFCGTPEYLAP 549
AL H + +RD+KP+N+LLD QG++ + DFGL L Q T CGTP Y AP
Sbjct: 135 SALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAP 194
Query: 550 ELLLGQGYTKV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
E++ +GY D W+ GV+L+ +L G P+ D ++ MY+KI + RFP K AK
Sbjct: 195 EVISRRGYDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHRRDYRFPSWISKQAK 254
Query: 609 DLLIGLLCRDPKRRL 623
++ +L +P R+
Sbjct: 255 SIIYQMLDPNPVTRM 269
>SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 338
Score = 143 bits (360), Expect = 1e-33
Identities = 94/306 (30%), Positives = 148/306 (47%), Gaps = 23/306 (7%)
Query: 371 PSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAE 430
P+ S+ F + VIGKGS+ V V+ R T + +ALK I K + ++ E
Sbjct: 19 PNATNFESVSQFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKKH-DEHKIKKLRNE 77
Query: 431 RTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELL 490
+L +++P + F+ K+YLV + GG+L YH+ + +F+ S R + EL+
Sbjct: 78 VLLLQSLNHPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHISQR-KFNESVIRIWMVELV 136
Query: 491 CALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLC-----KLNMKDQEKTTTFCGTPE 545
AL +H +++RD+KP+NILLD +GH L DF + + T GTP
Sbjct: 137 SALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPV 196
Query: 546 YLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPY----------YDEDVPKMYKKILQD 595
Y+APE L+ K DWW+LG+ YE L + P+ E+ L
Sbjct: 197 YMAPETLIHAVSYKESDWWSLGITFYECLFQVRPFPNHLLINWIRASEEEKASSADRLSS 256
Query: 596 PLRFPDD-----FDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGY 650
L D KDA+ ++ L D K+RLG H S ++++HPFF +S + +
Sbjct: 257 ALHISRDKKLTTISKDARSAVMAFLEMDIKKRLG-HSSKKLQTHPFFCSISLETVSKGNL 315
Query: 651 IPPYKP 656
P ++P
Sbjct: 316 TPIFRP 321
>Hs22042851 [T] KOG0986 G protein-coupled receptor kinase
Length = 266
Score = 143 bits (360), Expect = 1e-33
Identities = 81/203 (39%), Positives = 118/203 (57%), Gaps = 9/203 (4%)
Query: 462 INGGELFYHLQREGR--FDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHI 519
+NGG+L +H+ G FD R+ FY AEL C LE L I+YRDLKPENILLD +GHI
Sbjct: 1 MNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHI 60
Query: 520 ALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPP 579
+ D GL + + ++ GT Y+APE++ + YT DWW LG L+YEM+ G P
Sbjct: 61 RISDLGLA-TEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSP 119
Query: 580 Y--YDEDV--PKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDE--IKS 633
+ Y E V ++ ++I D + + F +DAK + LL ++P +RLG G +K
Sbjct: 120 FKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQ 179
Query: 634 HPFFNQLSWKRLKMKGYIPPYKP 656
HP F ++++RL+ PP+ P
Sbjct: 180 HPVFKDINFRRLEANMLEPPFCP 202
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 143 bits (360), Expect = 1e-33
Identities = 90/261 (34%), Positives = 141/261 (53%), Gaps = 18/261 (6%)
Query: 386 KVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFIVPL 445
+VIG G+F V + R R+T + YA+K I KS + K ++ + E ++ + +P IV L
Sbjct: 288 RVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDS--EILIIQSLSHPNIVKL 345
Query: 446 KFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRD 505
+++ ++YL+L ++ GG+LF + +F + +L AL +HD I++RD
Sbjct: 346 HEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRD 405
Query: 506 LKPENILL----DYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVV 561
LKPEN+L+ D + L DFGL K ++ T CGTP Y+APE+L +GY V
Sbjct: 406 LKPENLLVQRNEDKSTTLKLADFGLAKHVVR---PIFTVCGTPTYVAPEILSEKGYGLEV 462
Query: 562 DWWTLGVLLYEMLTGLPPYY--DEDVPKMYKKILQDPLRFP----DDFDKDAKDLLIGLL 615
D W GV+LY +L G PP+ + D +++ I F D+ AKDL+ LL
Sbjct: 463 DMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLL 522
Query: 616 CRDPKRRLGYHGSDEIKSHPF 636
DPK+R H ++ HP+
Sbjct: 523 VVDPKKRYTAH---QVLQHPW 540
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 142 bits (359), Expect = 1e-33
Identities = 91/252 (36%), Positives = 139/252 (55%), Gaps = 15/252 (5%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
+D+ +IG+GSF +V++V R T + YA+K I Y + EV + E VL RV +
Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGR-EVCES--ELRVLRRVRHAN 154
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
I+ L F++ E++Y+V+ GGELF + +G F + +L + LH I
Sbjct: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 214
Query: 502 IYRDLKPENILLDYQG---HIALCDFGLCKLNMKDQE---KTTTFCGTPEYLAPELLLGQ 555
+RDLKPEN+L + G I + DFGL K + KTT CGTPEY+APE+L+ +
Sbjct: 215 THRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTT--CGTPEYIAPEVLVRK 272
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD----FDKDAKDLL 611
YT VD W LGV+ Y +L+G P+ D++ ++Y++IL+ + + AKD +
Sbjct: 273 PYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFI 332
Query: 612 IGLLCRDPKRRL 623
LL DP R+
Sbjct: 333 DRLLTVDPGARM 344
>CE29300 [T] KOG0694 Serine/threonine protein kinase
Length = 431
Score = 142 bits (358), Expect = 2e-33
Identities = 92/284 (32%), Positives = 147/284 (51%), Gaps = 8/284 (2%)
Query: 373 THKHLSIDDFDLLKVIGKGSFGKVMQVRK-RDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
T ++ F L + +G+GSFG V D+ + +A+K K I+SK V E
Sbjct: 112 TRSVINEKSFVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREA 171
Query: 432 TVLARV-DNPFIVPLKFSFQSSEKLYLVLAFING--GELFYHLQREGRFDLSRSRFYTAE 488
++ + +PFI ++Q+ LY +L + G G+LF ++ G + R AE
Sbjct: 172 SIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAE 231
Query: 489 LLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLA 548
L A++ LH D+IYRD+K EN++LD GH L DFGL K +K T T CGT +Y++
Sbjct: 232 LASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAK-KLKQGSSTGTICGTLQYMS 290
Query: 549 PELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
P++ G Y+ VDWW+LGVLL+ +LTG+ PY + + + + P ++
Sbjct: 291 PDVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATH-HANLKFIDYSTPIGCSREFA 349
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIP 652
+L+ +L RL + +HPFF + + +L+ K Y P
Sbjct: 350 NLMDRMLAVSITHRL--CSFTVLHAHPFFRSIDFSKLEQKDYTP 391
>CE29299 [T] KOG0694 Serine/threonine protein kinase
Length = 436
Score = 142 bits (358), Expect = 2e-33
Identities = 92/284 (32%), Positives = 147/284 (51%), Gaps = 8/284 (2%)
Query: 373 THKHLSIDDFDLLKVIGKGSFGKVMQVRK-RDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
T ++ F L + +G+GSFG V D+ + +A+K K I+SK V E
Sbjct: 112 TRSVINEKSFVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREA 171
Query: 432 TVLARV-DNPFIVPLKFSFQSSEKLYLVLAFING--GELFYHLQREGRFDLSRSRFYTAE 488
++ + +PFI ++Q+ LY +L + G G+LF ++ G + R AE
Sbjct: 172 SIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAE 231
Query: 489 LLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLA 548
L A++ LH D+IYRD+K EN++LD GH L DFGL K +K T T CGT +Y++
Sbjct: 232 LASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAK-KLKQGSSTGTICGTLQYMS 290
Query: 549 PELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAK 608
P++ G Y+ VDWW+LGVLL+ +LTG+ PY + + + + P ++
Sbjct: 291 PDVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATH-HANLKFIDYSTPIGCSREFA 349
Query: 609 DLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIP 652
+L+ +L RL + +HPFF + + +L+ K Y P
Sbjct: 350 NLMDRMLAVSITHRL--CSFTVLHAHPFFRSIDFSKLEQKDYTP 391
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 142 bits (357), Expect = 2e-33
Identities = 89/276 (32%), Positives = 143/276 (51%), Gaps = 7/276 (2%)
Query: 367 VDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTH 426
V++ P + +++ K++G G+F KV R T + A+K + K + +
Sbjct: 7 VEFPPENRRGQLFGKYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGN 66
Query: 427 TLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYT 486
E ++ R+ +P IV L + K++ V+ F GGELF + + GRF SR Y
Sbjct: 67 IQREIAIMHRLRHPSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSK-GRFCEDLSRRYF 125
Query: 487 AELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKL--NMKDQEKTTTFCGTP 544
+L+ A+ H I +RDLKPEN+LLD + + + DFGL L ++ T CGTP
Sbjct: 126 QQLISAVGYCHSRGIFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTP 185
Query: 545 EYLAPELLLGQGYTKV-VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDF 603
Y+APE+L +GY +D W+ G++L+ + G P+ D ++ MY+KI + R P
Sbjct: 186 AYVAPEVLAKKGYDGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPKWT 245
Query: 604 DKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFNQ 639
D + LL LL +P+ R+ +EI P+F Q
Sbjct: 246 SPDLRRLLTRLLDTNPQTRITI---EEIIHDPWFKQ 278
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 142 bits (357), Expect = 2e-33
Identities = 90/283 (31%), Positives = 151/283 (52%), Gaps = 9/283 (3%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
+T +H I + L+K IGKG+F KV + T K A+K I K+ + + + E
Sbjct: 143 ATEEH--IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL-NPGSLQKLFREV 199
Query: 432 TVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
++ +D+P IV L ++ + LYL++ + +GGE+F +L GR +R +++
Sbjct: 200 RIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVS 259
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPEL 551
A++ H II+RDLK EN+LLD + +I + DFG K TFCG+P Y APEL
Sbjct: 260 AVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSN-EFTPGSKLDTFCGSPPYAAPEL 318
Query: 552 LLGQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
G+ Y VD W+LGV+LY +++G P+ + ++ +++L+ R P D ++L
Sbjct: 319 FQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENL 378
Query: 611 LIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPP 653
L L +P +R + I + N + ++ ++K YI P
Sbjct: 379 LRKFLVLNPAKRASL---ETIMGDKWMN-MGFEEDELKPYIEP 417
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 141 bits (355), Expect = 4e-33
Identities = 82/259 (31%), Positives = 141/259 (53%), Gaps = 6/259 (2%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD 438
+ + L K +GKG G V K A+K I + + S+S + E ++ +D
Sbjct: 15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLID 73
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHD 498
+P ++ L +++ + LYL+L ++GGELF +L ++GR +R + +++ AL+ H
Sbjct: 74 HPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 133
Query: 499 FDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT 558
I +RDLKPEN+LLD + +I + DFG+ L T+ CG+P Y PE++ G+ Y
Sbjct: 134 HSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETS-CGSPHYACPEVIRGEKYD 192
Query: 559 -KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCR 617
+ D W+ GV+LY +L G P+ D+++ ++ +K+ + P D + LL G++
Sbjct: 193 GRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEV 252
Query: 618 DPKRRLGYHGSDEIKSHPF 636
+P RRL EI HP+
Sbjct: 253 NPDRRLTL---AEINRHPW 268
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 140 bits (354), Expect = 5e-33
Identities = 93/299 (31%), Positives = 149/299 (49%), Gaps = 15/299 (5%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ I + L +G G+FGKV + T A+K + + I S V E L
Sbjct: 11 VKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+P I+ L + ++V+ +++GGELF ++ + GR + +R ++L A++
Sbjct: 71 FRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +++RDLKPEN+LLD + + DFGL + M D E T CG+P Y APE++ G+
Sbjct: 131 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM-MSDGEFLRTSCGSPNYTAPEVISGRL 189
Query: 557 YT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y VD W+ GV+LY +L G P+ DE VP ++KKI P+ ++ LL+ +L
Sbjct: 190 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHML 249
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFDQEFTRE 674
DP +R +I+ H +F Q +P Y P + D + D E +E
Sbjct: 250 QVDPLKRATI---KDIREHEWFKQ----------GLPSYLFPEDPSYDANVIDDEAVKE 295
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 140 bits (354), Expect = 5e-33
Identities = 87/263 (33%), Positives = 140/263 (53%), Gaps = 14/263 (5%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
+D+ +IG GSF +V++V ++ T K +A+K + + ++E +VL RV + +
Sbjct: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREAC---VSELSVLRRVSHRY 119
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
IV L F++ +++Y+V+ GGELF L +G F + + + LH I
Sbjct: 120 IVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQI 179
Query: 502 IYRDLKPENILLDYQGH---IALCDFGLCKLNMKDQEKTT-TFCGTPEYLAPELLLGQGY 557
+R+LKPEN+L + G I + DFGL K + T T CGTPEY+APE+LL + Y
Sbjct: 180 THRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPY 239
Query: 558 TKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD----FDKDAKDLLIG 613
T VD W LGV+ Y +L+G P+ DE ++Y+KIL+ + + AKD +
Sbjct: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
Query: 614 LLCRDPKRRLGYHGSDEIKSHPF 636
LL + R+ + + HP+
Sbjct: 300 LLILEAGHRM---SAGQALDHPW 319
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 140 bits (353), Expect = 7e-33
Identities = 90/252 (35%), Positives = 142/252 (55%), Gaps = 14/252 (5%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDN 439
D F++ +G+G+ V + +++ T K YALK ++K+ V K V E VL R+ +
Sbjct: 44 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT--VDKKIVR---TEIGVLLRLSH 98
Query: 440 PFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDF 499
P I+ LK F++ ++ LVL + GGELF + +G + + ++L A+ LH+
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 500 DIIYRDLKPENILLDY---QGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
I++RDLKPEN+L + + DFGL K+ ++ Q T CGTP Y APE+L G
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKI-VEHQVLMKTVCGTPGYCAPEILRGCA 217
Query: 557 YTKVVDWWTLGVLLYEMLTGLPPYYDEDVPK-MYKKILQDPLRFP----DDFDKDAKDLL 611
Y VD W++G++ Y +L G P+YDE + M+++IL F D+ +AKDL+
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLV 277
Query: 612 IGLLCRDPKRRL 623
L+ DPK+RL
Sbjct: 278 RKLIVLDPKKRL 289
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 140 bits (352), Expect = 9e-33
Identities = 88/263 (33%), Positives = 143/263 (53%), Gaps = 10/263 (3%)
Query: 379 IDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTV--LAR 436
I + + + +G+GSFGKV T + ALK I + ++ KS++ H ER + L
Sbjct: 31 IGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQ-LLKKSDM-HMRVEREISYLKL 88
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+ +P I+ L + + +V+ + GGELF ++ + R R + +++CA+E
Sbjct: 89 LRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYC 147
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H I++RDLKPEN+LLD ++ + DFGL + M D T CG+P Y APE++ G+
Sbjct: 148 HRHKIVHRDLKPENLLLDDNLNVKIADFGLSNI-MTDGNFLKTSCGSPNYAAPEVINGKL 206
Query: 557 YT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y VD W+ G++LY ML G P+ DE +P ++KK+ PD A+ L+ ++
Sbjct: 207 YAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMI 266
Query: 616 CRDPKRRLGYHGSDEIKSHPFFN 638
DP +R+ EI+ P+FN
Sbjct: 267 VADPMQRITI---QEIRRDPWFN 286
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 140 bits (352), Expect = 9e-33
Identities = 85/266 (31%), Positives = 148/266 (54%), Gaps = 9/266 (3%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLA-ERTVLAR 436
S+DDFD+ + +GKG FG V R++ T +I ALK + K+ ++ V+H L E +
Sbjct: 40 SLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLG-VSHQLKREIEIQYH 98
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR--SRFYTAELLCALE 494
+ +P I+ L F ++++++L + + GELF LQ + ++ + + +L AL
Sbjct: 99 LRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALH 158
Query: 495 ALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLG 554
H +I+RD+KPEN+LLD + ++ L DFG + D K T CGT +YLAPE++
Sbjct: 159 YCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVV--ADHSKRHTLCGTMDYLAPEMVSN 216
Query: 555 QGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGL 614
Q + VD W +G+LL+EML G P+ ++ K+ +I + + P A L+ +
Sbjct: 217 QPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDGAASLINAI 276
Query: 615 LCRDPKRRLGYHGSDEIKSHPFFNQL 640
+ ++P+ RL +I +HP+ ++
Sbjct: 277 IKKEPQERLPL---VDIMAHPWIKEM 299
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 139 bits (351), Expect = 1e-32
Identities = 92/304 (30%), Positives = 151/304 (49%), Gaps = 10/304 (3%)
Query: 323 NNSDIHLDSFHLPLNLKIDSASNIRLYNHHWIELESKMGKLNLSVDYKPSTHKHLSIDDF 382
N +D+ H ++D ++ +HH + K KL+ PS K D+
Sbjct: 28 NTADLVGKENHFKQTKRLDPNND----HHHQPAQKKKREKLSALCKTPPSLIKTRG-KDY 82
Query: 383 DLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPFI 442
+G+G F + Q+ K D+ +I+A K + K+ I S+ L+E + + +P I
Sbjct: 83 HRGHFLGEGGFARCFQI-KDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNI 141
Query: 443 VPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDII 502
V F+ +Y++L G L L+R RF+T ++ A++ +H +I
Sbjct: 142 VQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVI 201
Query: 503 YRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ--GYTKV 560
+RDLK NI D ++ + DFGL + + E+ T CGTP Y+APE+L+G+ G++
Sbjct: 202 HRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFE 261
Query: 561 VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDD--FDKDAKDLLIGLLCRD 618
VD W+LGV+LY +L G PP+ DV +Y++I FP D + K L+ +L D
Sbjct: 262 VDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLD 321
Query: 619 PKRR 622
P R
Sbjct: 322 PIER 325
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 139 bits (351), Expect = 1e-32
Identities = 95/280 (33%), Positives = 147/280 (51%), Gaps = 11/280 (3%)
Query: 364 NLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRK-RDTNKIYALKAIRKSYIVSKS 422
++ V+ +K +DL K++G G+F KV Q ++ + A+K ++K + K
Sbjct: 10 SIIVNVTGDDNKSALFGKYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRL--KD 67
Query: 423 EVT-HTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSR 481
+T H E +V+ R+ +P IV L + K+Y V+ GGELF + RF S
Sbjct: 68 GLTAHVKREISVMRRLRHPHIVLLSEVLATKTKIYFVMELAKGGELFSRVT-SNRFTESL 126
Query: 482 SRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGL--CKLNMKDQEKTTT 539
SR Y +L+ A+ H + +RDLKPEN+LLD + + DFGL K + T
Sbjct: 127 SRKYFRQLISAVRYCHARGVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHT 186
Query: 540 FCGTPEYLAPELLLGQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLR 598
CGTP Y+APELLL +GY D W+ GV+L+ + G P+ D ++ +Y+KI + +
Sbjct: 187 LCGTPAYVAPELLLKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYK 246
Query: 599 FPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPFFN 638
PD D + LL LL +P+ R+ +EI P+FN
Sbjct: 247 LPDWTSSDLRKLLRRLLEPNPELRITV---EEILKDPWFN 283
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 139 bits (350), Expect = 2e-32
Identities = 98/321 (30%), Positives = 165/321 (50%), Gaps = 15/321 (4%)
Query: 372 STHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAER 431
+T + I ++ L K IGKG+F KV R T + A+K I K+ + + + + E
Sbjct: 50 ATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREV 108
Query: 432 TVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLC 491
++ +++P IV L ++ + LYLV+ + +GGE+F +L GR +R +++
Sbjct: 109 RIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS 168
Query: 492 ALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPEL 551
A++ H I++RDLK EN+LLD +I + DFG K TFCG+P Y APEL
Sbjct: 169 AVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSN-EFTVGNKLDTFCGSPPYAAPEL 227
Query: 552 LLGQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDL 610
G+ Y VD W+LGV+LY +++G P+ +++ ++ +++L+ R P D ++L
Sbjct: 228 FQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENL 287
Query: 611 LIGLLCRDPKRRLGYHGSDEIKSHPFFNQLSWKRLKMKGYIPPYKPPVMGAMDTSNFD-- 668
L LL +P +R GS E + + + ++K PY P DT D
Sbjct: 288 LKKLLVLNPIKR----GSLEQIMKDRWMNVGHEEEELK----PYTEPDPDFNDTKRIDIM 339
Query: 669 --QEFTREQPVDSVVNDFLSE 687
F R++ D+++N E
Sbjct: 340 VTMGFARDEINDALINQKYDE 360
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 139 bits (350), Expect = 2e-32
Identities = 87/274 (31%), Positives = 139/274 (49%), Gaps = 16/274 (5%)
Query: 388 IGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTL----AERTVLARVDNPFIV 443
+G G FGKV TN+ A+K I+ K ++ H L E L + + I
Sbjct: 17 LGSGGFGKVRLATHLLTNQKVAIK------IIDKKQLGHDLPRVQTEMDALRNLSHQNIC 70
Query: 444 PLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIY 503
L ++ +K ++V+ + +GGE+F ++ R+ R + S +R + +L+ A+ +H +
Sbjct: 71 RLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQGYAH 130
Query: 504 RDLKPENILLDYQGHIALCDFGLCKLNMK---DQEKTTTFCGTPEYLAPELLLGQGYT-K 559
RDLKPEN+LL H+ L DFGLC K D+ T CG+P Y APEL+ G Y
Sbjct: 131 RDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSPAYAAPELIQGLQYKGN 190
Query: 560 VVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDP 619
D W++G+LLY +L G P+ D+++ MYKKI P+ +K LL +L P
Sbjct: 191 EADVWSMGILLYTLLVGALPFEDDNMQIMYKKIQSGCFYEPEFLSPLSKQLLRAMLQVVP 250
Query: 620 KRRLGYHG--SDEIKSHPFFNQLSWKRLKMKGYI 651
+RR+ + +H + + W + K +I
Sbjct: 251 ERRISVKKLLEHDWLNHKYTQPVKWNTIYDKNFI 284
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 139 bits (349), Expect = 2e-32
Identities = 88/283 (31%), Positives = 153/283 (53%), Gaps = 8/283 (2%)
Query: 355 ELESKMGKLNLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIR 414
EL SK+ N+ V +P + L K +GKG G V T + A+K +
Sbjct: 22 ELSSKIMSENI-VSTRPVAQAQYC-GPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVN 79
Query: 415 KSYIVSKSEVTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQRE 474
K + S+S + E ++ +++P ++ L +++ + LYL+L ++GGELF +L R+
Sbjct: 80 KEKL-SESVLQKVEREIAIMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRK 138
Query: 475 GRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQ 534
GR +R + +++ AL+ H +I +RDLKPEN+LLD + +I + DFG+ L ++
Sbjct: 139 GRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGMASLQVEGS 198
Query: 535 EKTTTFCGTPEYLAPELLLGQGYT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL 593
T+ CG+P Y PE++ G+ Y + D W+ GV+LY +L G P+ D+++ + +K+
Sbjct: 199 MLETS-CGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRNLLEKVK 257
Query: 594 QDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSDEIKSHPF 636
+ P D + LL ++ DP +R Y +D K HP+
Sbjct: 258 RGVFHIPHFVPADVQSLLRAMIEVDPGKR--YSLADVFK-HPW 297
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 139 bits (349), Expect = 2e-32
Identities = 81/254 (31%), Positives = 137/254 (53%), Gaps = 6/254 (2%)
Query: 382 FDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVDNPF 441
+D+ + IGKG+F V R R T A+K I KS + ++ + E ++ R+ +P
Sbjct: 141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQL-DQTNLQKVYREVEIMKRLKHPH 199
Query: 442 IVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDI 501
I+ L ++ +Y+V + + GE+F ++ + GR S +RF +++ A+E H I
Sbjct: 200 IIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGI 259
Query: 502 IYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYT-KV 560
++RDLK EN+LLD +I + DFG + K E T+CG+P Y APE+ G+ YT
Sbjct: 260 VHRDLKAENLLLDLNMNIKIADFGFSN-HFKPGELLATWCGSPPYAAPEVFEGKQYTGPE 318
Query: 561 VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLLCRDPK 620
+D W+LGV+LY ++ G P+ + + ++L R P + + L+ +L +P
Sbjct: 319 IDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPT 378
Query: 621 RRLGYHGSDEIKSH 634
RR + D+IK H
Sbjct: 379 RR---YTIDQIKRH 389
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 138 bits (348), Expect = 3e-32
Identities = 86/264 (32%), Positives = 135/264 (50%), Gaps = 5/264 (1%)
Query: 377 LSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLAR 436
+ I + L +G G+FGKV + T A+K + + I S V E L
Sbjct: 13 VKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 72
Query: 437 VDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCALEAL 496
+P I+ L + +++V+ +++GGELF ++ + GR D SR ++L ++
Sbjct: 73 FRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 132
Query: 497 HDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQG 556
H +++RDLKPEN+LLD + + DFGL + M D E T CG+P Y APE++ G+
Sbjct: 133 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM-MSDGEFLRTSCGSPNYAAPEVISGRL 191
Query: 557 YT-KVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIGLL 615
Y VD W+ GV+LY +L G P+ D+ VP ++KKI P + LL +L
Sbjct: 192 YAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHML 251
Query: 616 CRDPKRRLGYHGSDEIKSHPFFNQ 639
DP +R +I+ H +F Q
Sbjct: 252 QVDPMKRASI---KDIREHEWFKQ 272
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 138 bits (348), Expect = 3e-32
Identities = 89/284 (31%), Positives = 150/284 (52%), Gaps = 25/284 (8%)
Query: 361 GKLNLSVDYKPSTHKHLSIDD-FDLLKVIGKGSFGKVMQVRKRDT-NKIYALKAIRKSYI 418
GK + D K +K +SI++ ++L ++G G+F +V +D+ + +A+K I K +
Sbjct: 10 GKKAKAKDLK-ELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKAL 68
Query: 419 VSKSE-------------VTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGG 465
K E H + R+ +P IV L +++ K+YLV+ + GG
Sbjct: 69 KGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGG 128
Query: 466 ELFYHLQREGRFDLSRSRFYTAELLCALEALHDFDIIYRDLKPENILL---DYQGHIALC 522
ELF + +G + + ++L A++ +H+ +++RDLKPEN+L D I +
Sbjct: 129 ELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMIS 188
Query: 523 DFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYD 582
DFGL K M+D T CGTP Y+APE+L + Y K VD W++GV+ Y +L G PP+YD
Sbjct: 189 DFGLSK--MEDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYD 246
Query: 583 EDVPKMYKKILQDPLRFP----DDFDKDAKDLLIGLLCRDPKRR 622
E+ ++ +IL+ F D+ + AK + L+C ++R
Sbjct: 247 ENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKR 290
>Hs22053778_2 [T] KOG0986 G protein-coupled receptor kinase
Length = 510
Score = 138 bits (348), Expect = 3e-32
Identities = 105/333 (31%), Positives = 166/333 (49%), Gaps = 24/333 (7%)
Query: 364 NLSVDYKPSTHKHLSIDDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSE 423
N + +K + ++ + F +V+GKG FG+V + R T K+YA K + K I +
Sbjct: 131 NRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYAFKKLEKKRIKKQKG 190
Query: 424 VTHTLAERTVLARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGR--FDLSR 481
L E+ +L RV++ FIV L ++ ++ E L LVL +NGG+L +H+ GR F ++
Sbjct: 191 EAMALNEKQILERVNSRFIVSLAYTCETKEALCLVLTLMNGGDLNFHICHMGRAGFPEAQ 250
Query: 482 SRFYTAELLCALEALHDFDIIYRDLKPE--NILLDYQGHIALCDFGLCKLNMKDQEKTTT 539
+ FY +C L + + PE NILLD GHI + D GL +++ + +
Sbjct: 251 AVFY----IC-LRSGGPAPGAHSVQGPEARNILLDDHGHILVSDLGLA-VHVPEGQTIKG 304
Query: 540 FCGTPEYLAPELLLGQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKK------IL 593
GT Y+APE++ + YT D W LG L EM+ G + + KM K+ +
Sbjct: 305 RVGTVSYMAPEVVKNEPYTFSSDCWALGCLPQEMIAGQSLF--QQRKKMIKREEVERLVK 362
Query: 594 QDPLRFPDDFDKDAKDLLIGLLCRDPKRRLGYHGSD--EIKSHPFFNQLSWKRLKMKGYI 651
+DP + + F A LLC+DP RLG G E+K HP +L++KR+
Sbjct: 363 EDPEEYSERFSPQA---CSQLLCKDPAERLGCRGGSAREVKEHPLLKKLNFKRVGAGMLE 419
Query: 652 PPYKPPVMGAMDTSNFD-QEFTREQPVDSVVND 683
PP+KP D ++F+R + V+ D
Sbjct: 420 PPFKPDPRAIYCKDILDIKQFSRVKGVELEATD 452
>CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 392
Score = 137 bits (346), Expect = 4e-32
Identities = 84/277 (30%), Positives = 140/277 (50%), Gaps = 10/277 (3%)
Query: 378 SIDDFDLLKVIGKGSFGKVMQVRKR---DTNKIYALKAIRKSYIVS-KSEVTHTLAERTV 433
+I+DF++LK IG G++G+V VRK DT IYA+K + K + K V H E +
Sbjct: 25 TIEDFEILKHIGSGAYGEVAAVRKLNGCDTETIYAMKVMEKRRMSKHKDMVEH---EWKI 81
Query: 434 LARVDNPFIVPLKFSFQSSEKLYLVLAFINGGELFYHLQREGRFDLSRSRFYTAELLCAL 493
L + NPF + + +SFQ+ L V+ F GG++ ++ E + S + FY EL+ +
Sbjct: 82 LTTIHNPFFMKMSYSFQTKRHLVFVMPFAGGGDMLTMMENECLIEES-AHFYLCELVEGI 140
Query: 494 EALHDFDIIYRDLKPENILLDYQGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLL 553
LH+ I++RD+K EN+L+ GH+ + D+GL ++ GT +APE+ L
Sbjct: 141 GYLHEKHIVHRDVKLENLLIGNDGHLMITDYGLSATGCDAEDAIQGVIGTRHTMAPEVHL 200
Query: 554 GQGYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFPDDFDKDAKDLLIG 613
+ Y DWW +G+ +M + + D + + R P + +
Sbjct: 201 EKKYGTSCDWWAVGITYCDMRSDKAVFDGADSKEYSDSTAKKRPRLPKVLSPRERGFVNK 260
Query: 614 LLCRDPKRRLGY--HGSDEIKSHPFFNQLSWKRLKMK 648
L+ RDP +RLG G+ +K+H F + W+ + K
Sbjct: 261 LIVRDPTQRLGNGPDGTATVKAHDMFKGVVWEDVLAK 297
>At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 277
Score = 137 bits (346), Expect = 4e-32
Identities = 83/268 (30%), Positives = 140/268 (51%), Gaps = 12/268 (4%)
Query: 380 DDFDLLKVIGKGSFGKVMQVRKRDTNKIYALKAIRKSYIVSKSEVTHTLAERTVLARVD- 438
+++ L IG+G FG + + T + YA K I K ++ + E ++A +
Sbjct: 9 NNYQLCDEIGRGRFGTITRCFSPATKEFYACKTIDKRVLIDALDRECIETEPRIMAMLPP 68
Query: 439 NPFIVPLKFSFQSSEKLYLVLAFINGGELFYH--LQREGRFDLSRSRFYTAELLCALEAL 496
+P I+ + +++ + L +V+ ++ Y + GR S S Y ++L AL
Sbjct: 69 HPNIIRIFDLYETEDSLAIVMELVDPPMTIYDRLISAGGRLSESESASYAKQILSALAHC 128
Query: 497 HDFDIIYRDLKPENILLDY-QGHIALCDFGLCKLNMKDQEKTTTFCGTPEYLAPELLLGQ 555
H D+++RD+KP+N+L+D G + LCDFG E GTP Y+APE+++G+
Sbjct: 129 HRCDVVHRDVKPDNVLVDLVSGGVKLCDFGSAV--WLGGETAEGVVGTPYYVAPEVVMGR 186
Query: 556 GYTKVVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQDPLRFP----DDFDKDAKDLL 611
Y + VD W+ GV++Y ML G PP+ E +++ IL+ LRFP +AKDLL
Sbjct: 187 KYDEKVDIWSAGVVIYTMLAGEPPFNGETAEDIFESILRGNLRFPPKKFGSVSSEAKDLL 246
Query: 612 IGLLCRDPKRRLGYHGSDEIKSHPFFNQ 639
++CRD RR + D ++ FF++
Sbjct: 247 RKMICRDVSRR--FSAEDALRKSSFFSR 272
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,684,337
Number of Sequences: 60738
Number of extensions: 1773436
Number of successful extensions: 9369
Number of sequences better than 1.0e-05: 1653
Number of HSP's better than 0.0 without gapping: 551
Number of HSP's successfully gapped in prelim test: 1102
Number of HSP's that attempted gapping in prelim test: 5450
Number of HSP's gapped (non-prelim): 1941
length of query: 716
length of database: 30,389,216
effective HSP length: 114
effective length of query: 602
effective length of database: 23,465,084
effective search space: 14125980568
effective search space used: 14125980568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)