ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3309 good TZ KOG3699 Cytoskeleton Cytoskeletal protein Adducin
r_klactII3309 good TZ KOG3699 Signal transduction mechanisms Cytoskeletal protein Adducin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3309 1133715 1132846 -290
(290 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPBC359.06 [TZ] KOG3699 Cytoskeletal protein Adducin 222 4e-58
Hs7710117 [TZ] KOG3699 Cytoskeletal protein Adducin 94 2e-19
Hs7710115 [TZ] KOG3699 Cytoskeletal protein Adducin 94 2e-19
Hs5360206 [TZ] KOG3699 Cytoskeletal protein Adducin 94 2e-19
SPBC1289.14 [TZ] KOG3699 Cytoskeletal protein Adducin 92 1e-18
7302481 [TZ] KOG3699 Cytoskeletal protein Adducin 86 6e-17
CE28309 [TZ] KOG3699 Cytoskeletal protein Adducin 83 5e-16
CE28308 [TZ] KOG3699 Cytoskeletal protein Adducin 83 5e-16
CE06002 [TZ] KOG3699 Cytoskeletal protein Adducin 80 3e-15
Hs9257192 [TZ] KOG3699 Cytoskeletal protein Adducin 79 1e-14
Hs9257190 [TZ] KOG3699 Cytoskeletal protein Adducin 79 1e-14
Hs9257178 [TZ] KOG3699 Cytoskeletal protein Adducin 79 1e-14
Hs9951927 [TZ] KOG3699 Cytoskeletal protein Adducin 76 6e-14
Hs9943848 [TZ] KOG3699 Cytoskeletal protein Adducin 76 6e-14
>SPBC359.06 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 257
Score = 222 bits (566), Expect = 4e-58
Identities = 111/247 (44%), Positives = 152/247 (60%), Gaps = 2/247 (0%)
Query: 40 PQFKDKYEERRHTLEHMXXXXXXXXXXXXXXXXXXHVSVRDPVDRNTFWINPLGLHFSQM 99
P+F+D + +R+ L HM HV+VRDP+D NTFWINPL + FS M
Sbjct: 8 PEFEDLHTKRKWMLNHMAAAFRMFGRNGYNEGTAGHVTVRDPIDENTFWINPLEVPFSLM 67
Query: 100 TVSALVHVDEECNILPDGNQAAINAAGFKIHSHLHKARPDVNAACHTHSTYGKAWSAFGK 159
S LVH++ + I+ G++ N +GF IH +HK RP+V CH HS YGKA+SA GK
Sbjct: 68 KPSDLVHINSDGEII-GGSKMKYNTSGFAIHYEMHKVRPEVICVCHVHSIYGKAFSALGK 126
Query: 160 PLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQRLAEALGDNKAIILQNHGLLTVGETAD 219
PL+MLN D C+FY H +Y V+ EEG+R A+ L D KA+++QNHG++TVG T D
Sbjct: 127 PLDMLNTDCCVFYNNHGIYFDMDDVISMPEEGRRTAKGLADYKAVLVQNHGIMTVGTTVD 186
Query: 220 EAGYLFTLMEKCCQVQLLIESAVRSGLEKKLIGDEEADFTYFNTSDPETLYTEFQVDYDL 279
EA YL +LME+ CQ+QLLI+SA + G E+K + A N +P LYT Q ++
Sbjct: 187 EAAYLLSLMERSCQIQLLIDSATKVG-ERKHVHPTRAKAIRENADNPVGLYTAQQPNFLY 245
Query: 280 EMELTNG 286
E+ +NG
Sbjct: 246 EVACSNG 252
>Hs7710117 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 631
Score = 94.4 bits (233), Expect = 2e-19
Identities = 53/164 (32%), Positives = 94/164 (57%), Gaps = 4/164 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHL 133
H++ R ++ F I P GL +S++T S+LV ++ + +I+ G+ +N AGF +HS +
Sbjct: 168 HITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAI 227
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ ARPDV H H+ G A SA L ++ + Y + G+++++EE
Sbjct: 228 YAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL--GEVAYHDYHGILVDEEEKVL 285
Query: 194 LAEALG-DNKAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQL 236
+ + LG +K +IL+NHGL++VGE+ +EA Y + C++Q+
Sbjct: 286 IQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQV 329
>Hs7710115 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 768
Score = 94.4 bits (233), Expect = 2e-19
Identities = 53/164 (32%), Positives = 94/164 (57%), Gaps = 4/164 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHL 133
H++ R ++ F I P GL +S++T S+LV ++ + +I+ G+ +N AGF +HS +
Sbjct: 168 HITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAI 227
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ ARPDV H H+ G A SA L ++ + Y + G+++++EE
Sbjct: 228 YAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL--GEVAYHDYHGILVDEEEKVL 285
Query: 194 LAEALG-DNKAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQL 236
+ + LG +K +IL+NHGL++VGE+ +EA Y + C++Q+
Sbjct: 286 IQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQV 329
>Hs5360206 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 737
Score = 94.4 bits (233), Expect = 2e-19
Identities = 53/164 (32%), Positives = 94/164 (57%), Gaps = 4/164 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHL 133
H++ R ++ F I P GL +S++T S+LV ++ + +I+ G+ +N AGF +HS +
Sbjct: 168 HITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAI 227
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ ARPDV H H+ G A SA L ++ + Y + G+++++EE
Sbjct: 228 YAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL--GEVAYHDYHGILVDEEEKVL 285
Query: 194 LAEALG-DNKAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQL 236
+ + LG +K +IL+NHGL++VGE+ +EA Y + C++Q+
Sbjct: 286 IQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQV 329
>SPBC1289.14 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 324
Score = 91.7 bits (226), Expect = 1e-18
Identities = 54/161 (33%), Positives = 81/161 (49%), Gaps = 5/161 (3%)
Query: 78 VRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDG---NQAAINAAGFKIHSHLH 134
V +P +F INP GL + ++T S+L+ VDE+ NI G + IN AG+ IHS +H
Sbjct: 106 VEEPDGTASFLINPYGLRYGEITASSLIKVDEDGNIKHPGVTGDVFGINRAGYVIHSAIH 165
Query: 135 KARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQRL 194
+ARPDV + H H Y S L Q Y + G+V++ E + L
Sbjct: 166 RARPDVKSIMHNHYPYAAGVSCVKHGFLELAQ--TSHQSGPVTYHDYHGIVVDKGEQKSL 223
Query: 195 AEALGDNKAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQ 235
AE + + +IL+NHG++T E+ A YL ++Q
Sbjct: 224 AEDIANKDILILRNHGIITAAESVGAAYYLMYQFLAATEIQ 264
>7302481 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 1156
Score = 85.9 bits (211), Expect = 6e-17
Identities = 65/202 (32%), Positives = 104/202 (51%), Gaps = 10/202 (4%)
Query: 76 VSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHLH 134
++ R VD+ F +NP GL + ++T SAL VD + I+ G N + F +HS +H
Sbjct: 143 ITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVH 202
Query: 135 KARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQRL 194
ARPD+ A + + A S+ L L +D C+ + T ++ G+ ++EE RL
Sbjct: 203 AARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLGEITT--HAYTGL-FDEEERNRL 259
Query: 195 AEALGDN-KAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQLLIESAVRSGLEKKLIGD 253
+LG N K I+L NHG L GET +EA + + + C+ QL + + GL+ ++
Sbjct: 260 VRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKL---LPVGLDNLVLIP 316
Query: 254 EEADFTYFNTS--DPETLYTEF 273
EE+ + S PE L +F
Sbjct: 317 EESRKAIYEQSRRPPEDLEKKF 338
>CE28309 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 732
Score = 82.8 bits (203), Expect = 5e-16
Identities = 60/212 (28%), Positives = 103/212 (48%), Gaps = 10/212 (4%)
Query: 76 VSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHLH 134
+S R + NTF +NP GL + ++T + +V +DE IL G +A +N F +HS ++
Sbjct: 147 ISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGTLKAGVNQPAFLLHSAIY 206
Query: 135 KARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQRL 194
KA P V H H+ A ++ L L ++ + Y + + +D + +
Sbjct: 207 KAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVL--GPVGYHDYQDIGDDDIQFDEI 264
Query: 195 AEALGDNKAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQLLIESAVRSGLEKKLIGDE 254
LGD + L+N G L VG+T + A +L C+ Q+ A R+GL+ +I +E
Sbjct: 265 IANLGDKNVLFLRNQGFLVVGDTIEHATFLANNTVIACETQV---RAARAGLDNLIIPEE 321
Query: 255 EA-DFTYFNTSDPETLYTEFQVDY---DLEME 282
+A + N+ + +L VD+ +LE E
Sbjct: 322 KAIQRAFRNSRNTNSLKRNGTVDWRVGELEWE 353
>CE28308 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 679
Score = 82.8 bits (203), Expect = 5e-16
Identities = 60/212 (28%), Positives = 103/212 (48%), Gaps = 10/212 (4%)
Query: 76 VSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHLH 134
+S R + NTF +NP GL + ++T + +V +DE IL G +A +N F +HS ++
Sbjct: 147 ISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGTLKAGVNQPAFLLHSAIY 206
Query: 135 KARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQRL 194
KA P V H H+ A ++ L L ++ + Y + + +D + +
Sbjct: 207 KAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVL--GPVGYHDYQDIGDDDIQFDEI 264
Query: 195 AEALGDNKAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQLLIESAVRSGLEKKLIGDE 254
LGD + L+N G L VG+T + A +L C+ Q+ A R+GL+ +I +E
Sbjct: 265 IANLGDKNVLFLRNQGFLVVGDTIEHATFLANNTVIACETQV---RAARAGLDNLIIPEE 321
Query: 255 EA-DFTYFNTSDPETLYTEFQVDY---DLEME 282
+A + N+ + +L VD+ +LE E
Sbjct: 322 KAIQRAFRNSRNTNSLKRNGTVDWRVGELEWE 353
>CE06002 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 611
Score = 80.1 bits (196), Expect = 3e-15
Identities = 47/163 (28%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHL 133
H++VR D + IN G +S+++ S+L+ VD + ++ G+ +N AG+ +HS +
Sbjct: 380 HITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAI 439
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
H RP+V H H A SA L ++Q+ + Y + G+++++ E
Sbjct: 440 HNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMIV--GDVGYHEYRGILIDEAERAL 497
Query: 194 LAEALGDNKAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQL 236
L LGD +IL+NHG + GE+ + A L + C+ Q+
Sbjct: 498 LVRDLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQI 540
>Hs9257192 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 726
Score = 78.6 bits (192), Expect = 1e-14
Identities = 49/183 (26%), Positives = 99/183 (53%), Gaps = 5/183 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGNQA-AINAAGFKIHSHL 133
+V++R +++ F I+P G+ S++T S+L+ V+ ++ G+ ++ GF +HS +
Sbjct: 156 YVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAI 215
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ ARPDV H H+ A SA L ++ + + Y F G + ++ +
Sbjct: 216 YAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV--GDMAYYDFNGEMEQEADRIN 273
Query: 194 LAEALGDN-KAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQLLIESAVRSGLEKKLIG 252
L + LG K ++L+NHG++ +G+T +EA Y ++ C++Q+ S+ G+E ++
Sbjct: 274 LQKCLGPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSA-GGVENLILL 332
Query: 253 DEE 255
++E
Sbjct: 333 EQE 335
>Hs9257190 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 643
Score = 78.6 bits (192), Expect = 1e-14
Identities = 49/183 (26%), Positives = 99/183 (53%), Gaps = 5/183 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGNQA-AINAAGFKIHSHL 133
+V++R +++ F I+P G+ S++T S+L+ V+ ++ G+ ++ GF +HS +
Sbjct: 156 YVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAI 215
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ ARPDV H H+ A SA L ++ + + Y F G + ++ +
Sbjct: 216 YAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV--GDMAYYDFNGEMEQEADRIN 273
Query: 194 LAEALGDN-KAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQLLIESAVRSGLEKKLIG 252
L + LG K ++L+NHG++ +G+T +EA Y ++ C++Q+ S+ G+E ++
Sbjct: 274 LQKCLGPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSA-GGVENLILL 332
Query: 253 DEE 255
++E
Sbjct: 333 EQE 335
>Hs9257178 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 560
Score = 78.6 bits (192), Expect = 1e-14
Identities = 49/183 (26%), Positives = 99/183 (53%), Gaps = 5/183 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGNQA-AINAAGFKIHSHL 133
+V++R +++ F I+P G+ S++T S+L+ V+ ++ G+ ++ GF +HS +
Sbjct: 156 YVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAI 215
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ ARPDV H H+ A SA L ++ + + Y F G + ++ +
Sbjct: 216 YAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLV--GDMAYYDFNGEMEQEADRIN 273
Query: 194 LAEALGDN-KAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQLLIESAVRSGLEKKLIG 252
L + LG K ++L+NHG++ +G+T +EA Y ++ C++Q+ S+ G+E ++
Sbjct: 274 LQKCLGPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSA-GGVENLILL 332
Query: 253 DEE 255
++E
Sbjct: 333 EQE 335
>Hs9951927 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 674
Score = 75.9 bits (185), Expect = 6e-14
Identities = 48/164 (29%), Positives = 87/164 (52%), Gaps = 4/164 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHL 133
++SVR +++ I P GL FS+ T S LV V+ ++ G+ I+ GF H+ +
Sbjct: 160 YISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAI 219
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ RPDV H H+ A S+ + ++Q+ + Y + G + E EE +
Sbjct: 220 YSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLL--GDVAYYDYQGSLEEQEERIQ 277
Query: 194 LAEALGDN-KAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQL 236
L + LG + K ++L+NHG++ +GET +EA + ++ C++Q+
Sbjct: 278 LQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQV 321
>Hs9943848 [TZ] KOG3699 Cytoskeletal protein Adducin
Length = 706
Score = 75.9 bits (185), Expect = 6e-14
Identities = 48/164 (29%), Positives = 87/164 (52%), Gaps = 4/164 (2%)
Query: 75 HVSVRDPVDRNTFWINPLGLHFSQMTVSALVHVDEECNILPDGN-QAAINAAGFKIHSHL 133
++SVR +++ I P GL FS+ T S LV V+ ++ G+ I+ GF H+ +
Sbjct: 160 YISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAI 219
Query: 134 HKARPDVNAACHTHSTYGKAWSAFGKPLEMLNQDVCMFYKKHTVYESFGGVVLEDEEGQR 193
+ RPDV H H+ A S+ + ++Q+ + Y + G + E EE +
Sbjct: 220 YSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLL--GDVAYYDYQGSLEEQEERIQ 277
Query: 194 LAEALGDN-KAIILQNHGLLTVGETADEAGYLFTLMEKCCQVQL 236
L + LG + K ++L+NHG++ +GET +EA + ++ C++Q+
Sbjct: 278 LQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQV 321
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,081,764
Number of Sequences: 60738
Number of extensions: 694909
Number of successful extensions: 1411
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1385
Number of HSP's gapped (non-prelim): 14
length of query: 290
length of database: 30,389,216
effective HSP length: 105
effective length of query: 185
effective length of database: 24,011,726
effective search space: 4442169310
effective search space used: 4442169310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)