ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3338 good U KOG2114 Intracellular trafficking, secretion, and vesicular transport Vacuolar assembly/sorting protein PEP5/VPS11
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3338 1145763 1142701 -1021
(1021 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR231w [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11 850 0.0
Hs17978477 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11 129 2e-29
SPAC823.12 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11 116 2e-25
CE01618 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11 93 2e-18
At2g05170 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11 89 3e-17
SPAC16A10.03c [U] KOG2114 Vacuolar assembly/sorting protein PEP5... 70 2e-11
>YMR231w [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11
Length = 1029
Score = 850 bits (2197), Expect = 0.0
Identities = 433/1028 (42%), Positives = 651/1028 (63%), Gaps = 23/1028 (2%)
Query: 1 MSLNTWRQFQLYENIPIRDPFTESDQPLYSDPTLTAVASLNETYLAIAVQASVVKVVDLH 60
MSL++WRQFQL+ENIPIRDP D LYSDPTL A ++ L IAV ++++KVV L+
Sbjct: 1 MSLSSWRQFQLFENIPIRDPNFGGDSLLYSDPTLCAATIVDPQTLIIAVNSNIIKVVKLN 60
Query: 61 DMTLQFEFEAYTSEYQLTYLERVSDTLIVSVGECLGKPVLIKLWDLEKMPKDESKYHALA 120
+ EF+++ ++Q+T+L+ ++ +V++ E +GKP LI+++ LEK+P E YH+
Sbjct: 61 QSQVIHEFQSFPHDFQITFLKVINGEFLVALAESIGKPSLIRVYKLEKLPNREQLYHSQV 120
Query: 121 EVRNGSNAYPVSTVSCNLDASCIAVGFTDGRVILVRGDLLRDRGSKYRIIYEDSNKEPIT 180
E++NG+N YP+S VS + D SCI VGF +G++IL+RGD+ RDRGS+ RIIYED +KEPIT
Sbjct: 121 ELKNGNNTYPISVVSISNDLSCIVVGFINGKIILIRGDISRDRGSQQRIIYEDPSKEPIT 180
Query: 181 ALSLSNDGSRLFVTTTNKIMLFNTSGRNNGKPDMILNDSEGVDLNCGVLNRSTDEFICAL 240
AL L+ND + F TT++I+LFNT+GRN G+P ++LN G+DLNCG N +T+EFIC L
Sbjct: 181 ALFLNNDATACFAATTSRILLFNTTGRNRGRPSLVLNSKNGLDLNCGSFNPATNEFICCL 240
Query: 241 KDKLDIYMGSGSKRSLIVDIPTAKRIFPISADHILVLV--SNITTSSLHLGK-TPNETIR 297
+ ++ + SG K D+ KRIF + DHIL++ + + T+S+ + + +P R
Sbjct: 241 SNFIEFFSSSGKKHQFAFDLSLRKRIFCVDKDHILIVTEETGVPTTSISVNELSPTIINR 300
Query: 298 AVILDIKTKIISYSLLITSSVIDIFSDGAS----VNLLTSNGVIHKLRQKKLDDQLNTIC 353
I+D K KIIS + +++S++IDIFS S LLTS GV+H++ K L++Q+N I
Sbjct: 301 IFIIDAKNKIISLNFVVSSAIIDIFSTSQSGKNITYLLTSEGVMHRITPKSLENQINIII 360
Query: 354 QKDMYSVALELAKQHSLPDVKVQEIKKSYGDYLFKKGSKREAIEQYMGCIEVCDPTEIIS 413
QK++Y AL+LAKQHSL + VQEI K YGDYLFKKG ++EA +QY+ C++V + +EIIS
Sbjct: 361 QKELYPFALQLAKQHSLSPLDVQEIHKKYGDYLFKKGLRKEATDQYIQCLDVVETSEIIS 420
Query: 414 KFGVEHKTNSEDSINLKDFLWKLVKDGKAXXXXXXXXXXXXXXXXXIEGLGSFLSHFKRD 473
KFGV+ + E NL D+LW L+K+ + +EG+ +F+ HF R
Sbjct: 421 KFGVKEVPDPESMRNLADYLWSLIKNSISQRDHVTLLLIVLIKLKDVEGIDTFIQHFDRK 480
Query: 474 GVFNENPEEFGNWSMNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQKYVLKYSKDPSQV 533
G++NE M+ + + KYSKD +
Sbjct: 481 GIWNEGVVMD---DMDDVTFFYSDNDFFDLDLILELMKESDFKRLSYRLAKKYSKDSLII 537
Query: 534 VSIVLLHKKDSFGALNYIKSLPVDDALRVLIKFSRKLLDLIPNETNLLLIDLFIGQYKPS 593
V I+L + A+ YIKSLP+D+ LR L+ +S+KLL+ PNETN LLI++F G++KPS
Sbjct: 538 VDILLNLLHNPVKAIKYIKSLPIDETLRCLVTYSKKLLEESPNETNALLIEVFTGKFKPS 597
Query: 594 NYDAVKENVVNQKKQSEPADKEPIIFYNYRSFFEYML---PSSASSDDKPLTVESAQPTY 650
++ ++ + + ++ +FY+Y++FF YM S A S+ + E +PTY
Sbjct: 598 TFEV---DLDRRDTTGDFSENIRTVFYSYKTFFNYMNSNGTSDAMSESSEASHEHEEPTY 654
Query: 651 HPPKPSLIFPSFVQKPFQFVVFLEACLESYKRFQGYDQDRQDILTTLYDIYLSLYEDDIE 710
HPPKPS++F SFV KPF+FVVFLEACL Y++++G+D+DRQ ILTTLYD+YL+L ++D+
Sbjct: 655 HPPKPSIVFSSFVTKPFEFVVFLEACLACYQQYEGFDEDRQVILTTLYDLYLNLAQNDVP 714
Query: 711 ERKAEWKGKAEAVLEETEKYKIRQAS---ERAPDSSLMLLISHMHDMNPFTLSSMQEDEQ 767
ER +W+ +A VL E+ K AS + D+S+MLLISHM + + D
Sbjct: 715 ERIDDWRSRATGVLRESNKLVYSAASNNTSKRVDNSIMLLISHMDQSSASAKDKTKIDIA 774
Query: 768 ESNSIISHVSLSDVFRSMCLTNDPHVCLSFLEKYGESEHDLYKIAMPFFVSSKQIYEDIG 827
+ + L FR+M L +P CL FLEKYG E L ++A+ +FVS+K I++++G
Sbjct: 775 SFANDNPEMDLLSTFRAMTLNEEPSTCLKFLEKYGTEEPKLLQVALSYFVSNKLIFKEMG 834
Query: 828 GESVFREKILNKVLKFDLMSPLEIIQTLSGTNVVKYGAIKDFLVDYLKGENAEIQKNELL 887
G V +EK+L +++ + M L+II+ LS TNV +G I+D ++D++K E+ EI++NE L
Sbjct: 835 GNEVLKEKVLRPIIEGERMPLLDIIKALSRTNVAHFGLIQDIIIDHVKTEDTEIKRNEKL 894
Query: 888 VKSYEKELDLKVSKLKEALAIESPLQVQVKKRLCDACNILLEFPMVFFKCGHLYHQRCLN 947
++SY+KEL K KLK + + PL V +K + C C + L+ P+VFFKCGH+YHQ CLN
Sbjct: 895 IESYDKELKEKNKKLKNTINSDQPLHVPLKNQTCFMCRLTLDIPVVFFKCGHIYHQHCLN 954
Query: 948 EETDS----DLLYSCPQCVVETESAKKTMATYKNSSQNANLLRAALSDLDAKEDRFAIIS 1003
EE D+ L+ CP+C+V+ E++ K + +LL AL+ + DRF +I+
Sbjct: 955 EEEDTLESERKLFKCPKCLVDLETSNKLFEAQHEVVEKNDLLNFALNSEEGSRDRFKVIT 1014
Query: 1004 EFIGKGGL 1011
EF+G+G +
Sbjct: 1015 EFLGRGAI 1022
>Hs17978477 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11
Length = 941
Score = 129 bits (325), Expect = 2e-29
Identities = 93/356 (26%), Positives = 183/356 (51%), Gaps = 16/356 (4%)
Query: 68 FEAYTSEYQLTYLERVSD-TLIVSVGECL-GKPVLIKLWDLEKMPKDESKYHALAEVRNG 125
F+AY + ++T+L ++ ++ SVGE G L+K+W+LEK + G
Sbjct: 80 FQAY--KLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPG 137
Query: 126 SNAYPVSTVSCNLDASCIAVGFTDGRVILVRGDLLRDRGSKYRIIYEDSNKEPITALSLS 185
+ VS ++ + + + +A+GFTDG V L +GD+ RDR SK +I+++ + P+T L+
Sbjct: 138 TEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNY--PVTGLAFR 195
Query: 186 NDG--SRLFVTTTNKIMLFNTSGRNNGKPDMILNDSEGVDLNCGVLNRSTDEFICALKDK 243
G + LFV TT + + SG++ + ++ D+ G L C L+ + + +
Sbjct: 196 QAGKTTHLFVVTTENVQSYIVSGKDYPRVEL---DTHGCGLRCSALSDPSQDLQFIVAGD 252
Query: 244 LDIYMGSGSKRSLIVDIPTAKRIFPISADHILVLVSN--ITTSSLHLGKTPNETIRAV-- 299
+Y+ +R K I +++++ + ++ S + + + +
Sbjct: 253 ECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILN 312
Query: 300 ILDIKTKIISYSLLITSSVIDIFSDGASVNLLTSNGVIHKLRQKKLDDQLNTICQKDMYS 359
I D+ K I+YS + V+D+ ++ S+ +LT +G +H L++K +L + +K+++
Sbjct: 313 IYDLCNKFIAYSTVF-EDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFE 371
Query: 360 VALELAKQHSLPDVKVQEIKKSYGDYLFKKGSKREAIEQYMGCIEVCDPTEIISKF 415
+A+ LAK L + +I YGD+L+ KG+ A++QY+ I +P+ +I KF
Sbjct: 372 MAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKF 427
Score = 103 bits (256), Expect = 2e-21
Identities = 74/309 (23%), Positives = 139/309 (44%), Gaps = 28/309 (9%)
Query: 704 LYEDDIEERKAEWKGKAEAVLEE---TEKYKIRQASERAPDSSLMLLISHMHDMNPFTLS 760
+Y+ +E R W + + ++E E + ++ L++ MHD L
Sbjct: 622 IYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLY 681
Query: 761 SMQEDEQESNSIISHVSLSDVFRSMCLTNDPHVCLSFLEKYGESEHDLYKIAMPFFVSSK 820
+ E + I+ + + +R + +S E++GE + L++ A+ +F +
Sbjct: 682 -LYEQGKLFQQIMHYHMQHEQYRQV---------ISVCERHGEQDPSLWEQALSYFARKE 731
Query: 821 QIYEDIGGESVFREKILNKVLKFDLMSPLEIIQTLSGTNVVKYGAIKDFLVDYLKGENAE 880
+ ++ + +L + +LM PL ++QTL+ + I+D+LV L+ ++ +
Sbjct: 732 EDCKE------YVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQ 785
Query: 881 IQKNELLVKSYEKELDLKVSKLKEALAIESPLQVQVKKRLCDACNILLEFPMVFFKCGHL 940
I ++EL V+ Y +E +++E A Q K C CN LE P V F CGH
Sbjct: 786 IAQDELRVRRYREETTRIRQEIQELKASPKIFQ----KTKCSICNSALELPSVHFLCGHS 841
Query: 941 YHQRCLNEETDSDLLYSCPQCVVETESAKKTMATYKNSSQNANLLRAALSDLDAKEDRFA 1000
+HQ C ++SD CP C+ E +K M + Q +L L D F+
Sbjct: 842 FHQHCFESYSESDA--DCPTCLPEN---RKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFS 896
Query: 1001 IISEFIGKG 1009
+I+++ G+G
Sbjct: 897 VIADYFGRG 905
>SPAC823.12 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11
Length = 906
Score = 116 bits (291), Expect = 2e-25
Identities = 100/428 (23%), Positives = 189/428 (43%), Gaps = 58/428 (13%)
Query: 537 VLLHKKDSFGALNYIKSLPVDDALRVLIKFSRKLLDLIPNETNLLLIDLFIGQYKPSNYD 596
VL+ + AL + +SLP + L +L+K+ R LLD +P +T + I + ++ D
Sbjct: 515 VLVESEQYSEALRFFESLPPSNLLPLLLKYGRVLLDKLPEKTTNIFIQFYSNSHRG---D 571
Query: 597 AVKENVVNQKKQSEPADKEPIIFYNYRSFFEYMLPSS------ASSDDKPLTVESAQPTY 650
+ K ++ + + Y + LP S + +++ + S +Y
Sbjct: 572 LSTSESKGELKTAKSLRQTYLSLLPYAQVANFSLPPSLYEISPSQEENQRAALFSEDVSY 631
Query: 651 HPPKPSLIFPSFVQKPFQFVVFLEACLES----YKRFQGYDQDRQDILTTLYDIYL--SL 704
P P F F+ + + FLE L + YK I T L++ Y+ S
Sbjct: 632 TAPSPQTCFHIFLNHNSELISFLEGILPNASPNYKTL---------INTCLFEAYIRESF 682
Query: 705 YEDDIEERKAEWKGKAEAVLEETEKYKIRQASERAPDSSLMLLISHMHDMNPFTLSSMQE 764
++E+++ W+ K+ ++L++ EK D + + LIS + + ++
Sbjct: 683 ASSNVEKQEF-WQEKSNSLLKKVEKNV---------DLNAVFLISQILGFD----DGVRF 728
Query: 765 DEQESNSIISHVSLSDVFRSMCLTNDPHVCLSFLEKYGESEHDLYKIAMPFFVSSKQI-- 822
+ +S + D+FRS C ND L + +G + +LY + + F S + +
Sbjct: 729 VQGKSGQTL------DIFRSFCQQNDIERALKMVRVHGPDQQELYIMMLNCFASLENVDS 782
Query: 823 -YEDIGGESVFREKILNKVLKFDLMSPLEIIQTLSGTNVVKYGAIKDFLVDYLKGENAEI 881
Y+DI +I+N ++ L+SP +++ L + +K I D + L I
Sbjct: 783 WYQDIN-------EIVNIIVSQRLISPTQLLDILGKSVNIKLEHISDSMQSVLDNYRESI 835
Query: 882 QKNELLVKSYEKELDLKVSKLKEALAIESPLQVQVKKRLCDACNILLEFPMVFFKCGHLY 941
K ++ +++++ ++ L+I V++ C C I LE PMV F+CGH Y
Sbjct: 836 SKQNEAIEMGKRDIE----EITSQLSILRTRAFVVQESKCSTCGIDLELPMVHFRCGHSY 891
Query: 942 HQRCLNEE 949
HQRC+ +E
Sbjct: 892 HQRCVEDE 899
Score = 90.5 bits (223), Expect = 1e-17
Identities = 100/443 (22%), Positives = 191/443 (42%), Gaps = 51/443 (11%)
Query: 34 LTAVASLNETYLAIAVQASVVKVVDLHDMTLQ-FEFEAYTSEYQLTYLERVSDTLIVSVG 92
LT+ S N + A V + + +LQ + E +S Q+ +L+ + L +V
Sbjct: 26 LTSSFSSNGELVVFATAFGDVSIYNSSFKSLQSIKVEDESSIQQILWLDNKTFLLFSNVE 85
Query: 93 ECLGKPVLIKLWDLEKMPKDESKYHALAEVRNGS---NAYPVSTVSCNLDASCIAVGFTD 149
G + ++ + ++E L S + YP+ VS + IA GF
Sbjct: 86 GGTGTNSTVIIYAFSQADENEPPQFVLVTTHKFSINESPYPIIAVSQSPIDKTIACGFGG 145
Query: 150 GRVILVRGDLLRDRGSKYRIIYEDSNKEPITALS-LSNDGSRLFVTTTNKIMLFNTSGRN 208
G V G+ LR+RG K Y + EPIT L+ L + S LF+ TTNK ++ SG++
Sbjct: 146 GLVSCYHGNPLRERGIKNS--YSHNLGEPITGLTYLDDQSSVLFIATTNKT--YSLSGKS 201
Query: 209 NGKPDMILNDSEGVDLNCGVLNRST---------DEFICALKDKLDIYMGSGSKRSLIVD 259
+ D+ GV LNC ++T F+C L Y + +
Sbjct: 202 -----LSCLDNTGVSLNCSSSCKTTPLQSREKNSSSFVCTRSSGLTFY--DSKREKICFT 254
Query: 260 IPTAKRIFPISADHILVLVSNI--TTSSLHLG-----------------KTPNETIRAVI 300
P K + + + + T SS + G + P R ++
Sbjct: 255 FPGEKHYMTVMGSILALCYTPTLGTDSSTNEGLKKSFSSSSSIRKADASRNPAFPPRLLL 314
Query: 301 LDIKTKIISYSLLITSSVIDIFSDGASVNLLTSNGVIHKLRQKKLDDQLNTICQKDMYSV 360
+D+ +I + + + I ++T++ + +L++ L ++++ +CQK MY++
Sbjct: 315 VDLSRNLIVWEGHLKDVAVSILPLKHGFLVVTADDNVFELKRITLQEEISLLCQKMMYNL 374
Query: 361 ALELAKQHSLPDVKVQE-IKKSYGDYLFKKGSKREAIEQYMGCIEVCDPTEIISKFGVEH 419
A+ LAK+ ++ D++ +E + + Y +LF++G +++ Y+ I+ D + +F
Sbjct: 375 AISLAKKENM-DIEFRESLMRDYASFLFRRGDFSASMDWYIRSIKSIDIPSVCLEF---- 429
Query: 420 KTNSEDSINLKDFLWKLVKDGKA 442
+++ L L +L+K G A
Sbjct: 430 -LKAQEIKQLIRLLEELIKTGLA 451
>CE01618 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11
Length = 950
Score = 92.8 bits (229), Expect = 2e-18
Identities = 92/381 (24%), Positives = 183/381 (47%), Gaps = 41/381 (10%)
Query: 62 MTLQFEFEAYTSEYQLTYLERVS-DTLIVSVGECLGKP-VLIKLWDLEKMPKDESKYHAL 119
+T QF E Y YQ + S D + S+GE L+K+WD E++ K+ H +
Sbjct: 57 LTNQFS-EYYWKAYQKSLASLHSADKYLFSIGEDDETVNTLLKIWDPERVEKNTP--HVM 113
Query: 120 AEVR----NGSNAYPVSTVSCNLDASCIAVGFTDGRVILVRGDLLRDRGSKYRII-YEDS 174
+R N +++ P +++ + + VG+TDG V+ +GD+L D+ R I DS
Sbjct: 114 RTIRMSPLNPTSSSPACSIAVHSSLQSVVVGYTDGTVLFYQGDVLHDKSLNSRWIKVRDS 173
Query: 175 N--KEPITALSLSNDGSRLFVTTTNKIMLFNTSGRN-------NGKPDMI--LNDSEGVD 223
+ + +T L+++ V +K ++F + ++ NG+ + +D+ G
Sbjct: 174 SVGEGSVTGLAIA-------VLPASKTVVFVITQKHVHSYVLENGRTVIAHKKHDANGAT 226
Query: 224 LNCGVLNRSTDEFICALKDKLDIYM--------GSGSKRSLIVDIPTAKRIFPISADHIL 275
+C + ST + I A ++ L Y G R L + K S ++
Sbjct: 227 ADCWTFDESTGQLIVASREMLFFYDADQCIDMDGGEVGRCLQLGRGHEKLQLVASGQYLA 286
Query: 276 VLVSNITTSSLHLGKTPNETIRAV-ILDIKTKIISYSLLITSSVIDIFSDGASVNLLTSN 334
+L + SL + +E + + + DIK + + +S + + + +F G+++ +L+ +
Sbjct: 287 LLTKH---HSLIQKERDSEFMTMLSVYDIKGQYVGFSCSLPN-LCRLFIAGSTMLVLSHD 342
Query: 335 GVIHKLRQKKLDDQLNTICQKDMYSVALELAKQHSLPDVKVQEIKKSYGDYLFKKGSKRE 394
G++ +L +K L +L+ + +K M+ VA+ +AK ++ I YG+YL+ KG
Sbjct: 343 GLLSELIEKNLATKLDILVKKSMFDVAVLIAKNSRDGGDYLKGIHAKYGNYLYGKGDYEN 402
Query: 395 AIEQYMGCIEVCDPTEIISKF 415
AI+QY I + +P+ ++ ++
Sbjct: 403 AIQQYKETIGMLEPSYVMKRY 423
Score = 55.5 bits (132), Expect = 4e-07
Identities = 36/131 (27%), Positives = 62/131 (46%), Gaps = 11/131 (8%)
Query: 848 PLEIIQTLSGTNVVKYGAIKDFLVDYLKGENAEIQKNELLVKSYEK---ELDLKVSKLKE 904
PL +++ L+ + +++D+++ +L+ + I+++ +K K ELD V LK
Sbjct: 704 PLVVLELLAKNEHLTISSVRDYIIAWLRKQQIIIEEDRNTIKENNKAMGELDGTVESLKF 763
Query: 905 ALAIESPLQVQVKKRLCDACNILLEFPMVFFKCGHLYHQRCLNEETDSDLLYSCPQCVVE 964
I +QV K C AC+ L+ P V F C H YH C E + D CP C
Sbjct: 764 NAQI-----MQVTK--CSACDTPLQLPTVHFLCKHAYHVHCF-ESYNMDGSDKCPACQTT 815
Query: 965 TESAKKTMATY 975
++ + +Y
Sbjct: 816 RDTTRDEEISY 826
>At2g05170 [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11
Length = 932
Score = 89.4 bits (220), Expect = 3e-17
Identities = 93/438 (21%), Positives = 199/438 (45%), Gaps = 47/438 (10%)
Query: 57 VDLHDMTLQFE--FEAYTSEYQLTYLERVSD-TLIVSVGEC-----LGKPVLIKLWDLEK 108
V D ++F+ F+A++S + +L+ + +V+VGE + +K++DL+K
Sbjct: 45 VSFLDRGVKFDSGFQAHSSS--VLFLQHLKQRNFLVTVGEDEQISPQQSGMCLKVFDLDK 102
Query: 109 MPKDESKYHA---LAEVRNGSNAYPVSTVSCNLDAS------CIAVGFTDGRVILVRGDL 159
+ ++ + A + +R +N +P + ++ L IA+G +G + V+GD+
Sbjct: 103 VQEEGTSSSAPECIGILRIFTNQFPEAKITSFLVLEEVPPILLIAIGLDNGCIYCVKGDI 162
Query: 160 LRDRGSKYRIIYEDSNKEPITALSLSNDGSRL--FVTTTNKIMLFNTSGRNNGKPDMILN 217
R+R +++++ + + IT L DG L F T + LF+ + P +
Sbjct: 163 ARERITRFKL--QVDGRSAITGLGFRMDGQALLLFAVTPESVNLFSMQAQ---PPKLQTL 217
Query: 218 DSEGVDLNCGVLNRSTDEFICALKDKLDIYMGSGSKRSLIVDIPTAKRIFPISADHILVL 277
D G +N ++ E I + + Y G R K+ ++L +
Sbjct: 218 DHIGGSVNTVTMS-DRSELIVGRPEAVYFYEVDG--RGPCWAFEGEKKFMGWFRGYLLCV 274
Query: 278 VSNITTSSLHLGKTPNETIRAVILDIKTKIISYSLLITSSVIDIFSDGASVNLLTSNGVI 337
+ + KT N + D++ ++I+YS+++ V ++ + ++ L+ ++ +
Sbjct: 275 IDD--------SKTGNTVFN--VYDLRNRLIAYSIVV-DKVSNMLCEWGNIILIKADKSL 323
Query: 338 HKLRQKKLDDQLNTICQKDMYSVALELAKQHSLPDVKVQEIKKSYGDYLFKKGSKREAIE 397
+ +K ++ +L+ + +K++Y+VA+ L + + + YGD+L+ K EA+
Sbjct: 324 LCITEKDMESKLDMLFKKNLYTVAINLVQSQHADAAATANVMRKYGDHLYGKQDFDEAML 383
Query: 398 QYMGCIEVCDPTEIISKFGVEHKTNSEDSINLKDFLWKLVKDGKAXXXXXXXXXXXXXXX 457
QY+ I +P+ +I KF +++ NL ++L KL + G A
Sbjct: 384 QYINTIGYLEPSFVIQKF-----LDAQRIYNLTNYLEKLHEKGLASKDHTTLLLNCYTKL 438
Query: 458 XXIEGLGSFLSHFKRDGV 475
+E L +F+ K DG+
Sbjct: 439 KDVEKLNTFIR--KEDGI 454
Score = 80.5 bits (197), Expect = 1e-14
Identities = 51/184 (27%), Positives = 93/184 (49%), Gaps = 14/184 (7%)
Query: 828 GESVFRE--KILNKVLKFDLMSPLEIIQTLSGTNVVKYGAIKDFLVDYLKGENAEIQKNE 885
GE +E ++L + + D++ P+ ++QTL+ + IKD++ L+ E+ I+++
Sbjct: 751 GEDCTKEVKEVLTYIERDDILPPIIVLQTLAKNPCLTLSVIKDYIARKLEQESKIIEEDR 810
Query: 886 LLVKSYEKELDLKVSKLKEALAIESPLQVQVKKRLCDACNILLEFPMVFFKCGHLYHQRC 945
V+ Y+ E + K E L + + Q+ K C AC L+ P V F C H +HQRC
Sbjct: 811 RAVEKYQ-ETTKNMRKEIEDLRTNARI-FQLSK--CTACTFTLDIPAVHFMCMHSFHQRC 866
Query: 946 LNEETDSDLLYSCPQCVVETESAKKTMATYKNSSQNANLLRAALSDLDAKEDRFAIISEF 1005
L + CP+C E S + + + +S++ +L + +D F++I+E+
Sbjct: 867 LGDNEK-----ECPECAPEYRSVMEMKRSLEQNSKDQDLF---FQQVKGSKDGFSVIAEY 918
Query: 1006 IGKG 1009
GKG
Sbjct: 919 FGKG 922
>SPAC16A10.03c [U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11
Length = 860
Score = 69.7 bits (169), Expect = 2e-11
Identities = 81/333 (24%), Positives = 144/333 (42%), Gaps = 22/333 (6%)
Query: 99 VLIKLWDLEKMPKDESKY------HALAEVRNGSNAYPVSTVSCNLDASCIAVGFTDGRV 152
V ++ W L K S H L + N +P +++ ++D + GF +G V
Sbjct: 107 VYLQFWSLNPSKKTNSNSPLCLYEHRLYGIPNPP--FPATSLYVSIDIKTVVCGFANGLV 164
Query: 153 ILVRGDLLRDRGSKYRIIYEDSNKEPITALSLSNDGSRLFVTTTNKIMLFNTSGRNNGKP 212
I V GD +RD GS+ II + K+ IT L L + +LFV+TT ++M++ +NN K
Sbjct: 165 IRVEGDFVRDLGSRQDIILRE--KDSITNLILYSP-KKLFVSTTTQVMVYKI--KNNTKK 219
Query: 213 DMILNDSEGVDLNCGVLNRSTDEFICALKDKLDIYMGSGSKRSLIVDIPTAKRIFPISAD 272
+ + G+ L C + + +CA L +Y + + + S
Sbjct: 220 ---VISNHGIPLFCSIQYQG-KYIMCAGGSFLSVYTTPDMQLQNTYCVDGTFELLFSSFG 275
Query: 273 HILVLVSNITTSSLHLGKTPNETIRAV-ILDIKTKIISYSLLITSSVIDIFSDGASVNLL 331
+ V+ T + G N +IR + LD++ + + Y L+ S +IF +
Sbjct: 276 LVFVV---YTRKNGENGLENNSSIREIKALDVEKRYVLYESLLEQSYDNIFFNSFDCIFF 332
Query: 332 TSNGVIHKLRQKKLDDQLNTICQKDMYSVALELAKQHSLPDVKVQEIKKSYGDYLFKKGS 391
+S V +L + D L + K + A ++A P+ ++E + ++ +
Sbjct: 333 SSTKVPCQLIRLPSDFVLCKMKGKKEHKDAFKIANYLGSPEDTIRECALAAAGECRQQLN 392
Query: 392 KREAIEQYMGCIEVCDPTEIISKFGVEHKTNSE 424
++A Y+ I D EII KF +E K E
Sbjct: 393 FQDATYYYIEAIPFSDSAEII-KFYLEKKLIKE 424
Score = 51.2 bits (121), Expect = 8e-06
Identities = 50/206 (24%), Positives = 89/206 (42%), Gaps = 39/206 (18%)
Query: 766 EQESNSIISHVSLS---DVFRSMCLTNDPHVCLSFLEKYGESEHDLYKIAMPFFVSSKQI 822
+Q ++ + SH+SL D + +DP + E Y SE L+ + FFV + I
Sbjct: 650 KQVTDLLYSHLSLKEGQDDSLIQQIISDPETVKTLSETYS-SEDALH--VLKFFVRERSI 706
Query: 823 ---YEDIGGESVFREKILNKVLKFDLMS---PLE-IIQTLSGTNVVKYGAIKDFLVDYLK 875
YEDI L K+L+ M P++ ++ L + + +K L+ ++
Sbjct: 707 TNKYEDI----------LYKILEACFMQFRIPIQHVLNILVKDGTLNFCFLKPLLLKWMN 756
Query: 876 GENAEIQKNELLVKSYEKELDLKVSKLKEALAIESPLQVQVKKRLCDACNILLEFPMVFF 935
I +N+ ++ + +++ K L +Q +++CD C LL+ P V +
Sbjct: 757 DYETRIHQNDDEIQVIKNDIEKKRQLLGT---------IQDSEKVCDNCEGLLDVPFVSY 807
Query: 936 KCGHLYHQRCLNEETDSDLLYSCPQC 961
C HL H+ C E CP+C
Sbjct: 808 SCLHLVHRDCATETV-------CPKC 826
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,600,713
Number of Sequences: 60738
Number of extensions: 2510348
Number of successful extensions: 8008
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 7970
Number of HSP's gapped (non-prelim): 17
length of query: 1021
length of database: 30,389,216
effective HSP length: 116
effective length of query: 905
effective length of database: 23,343,608
effective search space: 21125965240
effective search space used: 21125965240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)