ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3379 good E KOG1287 Amino acid transport and metabolism Amino acid transporters
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3379 1160833 1159100 -578
(578 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR055w [E] KOG1287 Amino acid transporters 850 0.0
YHL036w [E] KOG1287 Amino acid transporters 211 2e-54
Hs7657591 [E] KOG1287 Amino acid transporters 153 6e-37
Hs21361563 [E] KOG1287 Amino acid transporters 131 3e-30
HsM4507055 [E] KOG1287 Amino acid transporters 130 5e-30
7294339 [E] KOG1287 Amino acid transporters 130 5e-30
Hs19923170 [E] KOG1287 Amino acid transporters 130 7e-30
Hs4507053 [E] KOG1287 Amino acid transporters 127 5e-29
7297908 [E] KOG1287 Amino acid transporters 123 9e-28
7301546 [E] KOG1287 Amino acid transporters 122 1e-27
Hs7657683 [E] KOG1287 Amino acid transporters 119 1e-26
CE22438 [E] KOG1287 Amino acid transporters 118 2e-26
CE03266 [E] KOG1287 Amino acid transporters 116 8e-26
CE28440 [E] KOG1287 Amino acid transporters 113 9e-25
Hs6912670 [E] KOG1287 Amino acid transporters 108 3e-23
7292991 [E] KOG1287 Amino acid transporters 107 5e-23
CE07491 [E] KOG1287 Amino acid transporters 107 6e-23
Hs9790235 [E] KOG1287 Amino acid transporters 105 2e-22
CE07028 [E] KOG1287 Amino acid transporters 105 2e-22
CE27888 [E] KOG1287 Amino acid transporters 101 4e-21
CE09028 [E] KOG1287 Amino acid transporters 101 4e-21
7302046 [E] KOG1287 Amino acid transporters 100 8e-21
Hs20270383 [E] KOG1287 Amino acid transporters 94 6e-19
CE17028 [E] KOG1287 Amino acid transporters 83 1e-15
CE06416 [E] KOG1287 Amino acid transporters 82 2e-15
At5g04770 [E] KOG1286 Amino acid transporters 77 5e-14
At3g10600 [E] KOG1286 Amino acid transporters 70 1e-11
CE17868 [E] KOG1287 Amino acid transporters 69 1e-11
Hs17439329 [E] KOG1286 Amino acid transporters 64 6e-10
YGR191w [E] KOG1286 Amino acid transporters 61 5e-09
CE09606 [E] KOG1286 Amino acid transporters 59 2e-08
At1g17120 [E] KOG1286 Amino acid transporters 59 2e-08
At5g36940 [E] KOG1286 Amino acid transporters 57 1e-07
Hs13654280 [E] KOG1287 Amino acid transporters 54 6e-07
SPBPB2B2.01 [E] KOG1286 Amino acid transporters 53 1e-06
SPCC74.04 [E] KOG1289 Amino acid transporters 50 7e-06
>YGR055w [E] KOG1287 Amino acid transporters
Length = 574
Score = 850 bits (2195), Expect = 0.0
Identities = 411/543 (75%), Positives = 475/543 (86%), Gaps = 3/543 (0%)
Query: 1 MSGSRSFLSQLNVFNKDNYEISTDSKTLDTDANPTGTSDDNRS-VETGEHFDVELDKGSK 59
MS R+FLSQLNVFNK+NY+ S+ S T +N T +D+ S E G+ F ELD+G K
Sbjct: 1 MSEGRTFLSQLNVFNKENYQFSS-STTKKEVSNSTVDADNGASDFEAGQQFATELDQGEK 59
Query: 60 KLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGT 119
+LG++SCIGLICNRMLGTG+FAVSSTIYTL GSVGLALIMWAVGAIIA++GLYVYMEFGT
Sbjct: 60 QLGILSCIGLICNRMLGTGVFAVSSTIYTLCGSVGLALIMWAVGAIIAISGLYVYMEFGT 119
Query: 120 AIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADITEWN 179
AIP+NGGEKNYLE IF PKFF+TCMY AY+FFLGWAAGNS+NTA+MFLTAA+ ++T+WN
Sbjct: 120 AIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADTEVTKWN 179
Query: 180 QRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLKDGYKTD 239
QRGIGVAVV FAFLINS+NVK+GLY+QNILGIFKIG+VLFI++TGWVALGGGLKDGY++
Sbjct: 180 QRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSH 239
Query: 240 NFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLA 299
NF NAFEGT ATAYGIVNALY+VIWSFVGYSNVNYALGEVKNPVRTLKIAGPTS++FLA
Sbjct: 240 NFRNAFEGTETATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLA 299
Query: 300 IVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNVMSVI 359
I+YIFVNIAYFAVVPK+ +SKLIL ADFF++ F LVGLSALGNV+SVI
Sbjct: 300 IIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVF-GGQAKRAAAALVGLSALGNVLSVI 358
Query: 360 FSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPPAGDAYNFVLN 419
FSQGRIIQQLGREGVLPFSNFFA+SKPF+SP VGLFQHFIVCTVTI+APP GDAY V N
Sbjct: 359 FSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPPPGDAYLLVQN 418
Query: 420 LISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLANLYLIVAPYIPP 479
LISYPMNI+NF ISAGLLWI+W+R++G+ W+PPIKAG+ V FF L+NLYLI+APY+PP
Sbjct: 419 LISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPP 478
Query: 480 SNGESVYQSLPYWIHCVVAWGIFAVGGIYWVVWAVVLPKIGKYELVHEEVLGEDGFWRQK 539
SNGESVY S+PYWIHCV+AWGIF GG+Y+VVWA +LP+ G Y+LV ++VLGEDGFWR K
Sbjct: 479 SNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVK 538
Query: 540 IAK 542
IAK
Sbjct: 539 IAK 541
>YHL036w [E] KOG1287 Amino acid transporters
Length = 546
Score = 211 bits (537), Expect = 2e-54
Identities = 139/486 (28%), Positives = 244/486 (49%), Gaps = 12/486 (2%)
Query: 52 VELDKGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALI-MWAVGAIIALAG 110
+E+ +G + LG+ S + L +R++G+GIFAV S I +G L +W A IA AG
Sbjct: 57 MEVPQG-RHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAG 115
Query: 111 LYVYMEFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTA 170
LY+++EFG+ IP++GG KN+LER F P+ ++ ++ Y G+A S+ L+A
Sbjct: 116 LYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSA 175
Query: 171 ANADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGG 230
W+ + + ++ + FA LI+ V+V+ G++IQN LG K+ +++ + G L
Sbjct: 176 FGVTDDSWS-KYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFF 234
Query: 231 GLKDGYKT-DNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKI 289
G D E + I A + + F G+ V+ E+KNPV+TLK+
Sbjct: 235 YKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKV 294
Query: 290 AGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGL 349
+GP SLI + Y +N+AY V+ E ++ ++ + F F + +
Sbjct: 295 SGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAI 354
Query: 350 SALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGL-FQHFIVCTVTIIAP 408
SA N++ VI+S R+ Q++ +EG LPFS + + PFD+P + FI +I P
Sbjct: 355 SAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILP 414
Query: 409 PAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLAN 468
G+++N+++++ Y ++ GL ++ K P I+A + + +
Sbjct: 415 KEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHKNE----VPEIRASTFGVLAIITLS 470
Query: 469 LYLIVAPYIPPSNGESVYQSLPYWIHCVVAWGIFAVGGIYWVVWAVVLPKIGKYELVHEE 528
LY+++AP+ + V PY I ++ + +W+V V+LPK Y+L+ +
Sbjct: 471 LYMLMAPFFADPSLNRVGFLPPYQIMSLL---VIVACFFFWLVKFVLLPKFFHYKLLPKI 527
Query: 529 VLGEDG 534
DG
Sbjct: 528 TYLHDG 533
>Hs7657591 [E] KOG1287 Amino acid transporters
Length = 487
Score = 153 bits (387), Expect = 6e-37
Identities = 124/462 (26%), Positives = 219/462 (46%), Gaps = 47/462 (10%)
Query: 39 DDNRSVETGEHFDVELDKGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALI 98
+D +S+++ E L K +LGLIS I +I ++G+GIF ++ + + +VG LI
Sbjct: 11 EDEKSIQSQEPKTTSLQK---ELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLI 67
Query: 99 MWAVGAIIALAGLYVYMEFGTAIPRNGGEKNYLERIF-PAPKFFVTCMYGAYVFFLGWAA 157
+WA ++A G + E GT I ++GGE YL + P P AY+F WA+
Sbjct: 68 IWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIP---------AYLF--SWAS 116
Query: 158 G---NSVNTAVMFLTAANADITEWNQ---------RGIGVAVVGFAFLINSVNVKVGLYI 205
+ A++ L+ + + + + A + F +NS++V++G Y+
Sbjct: 117 LIVIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYV 176
Query: 206 QNILGIFKIGVVLFIAVTGWVALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIW 265
QNI K+ +V I ++G V L G T NF N+FEG + I A YN +W
Sbjct: 177 QNIFTAAKLVIVAIIIISGLVLLAQG-----NTKNFDNSFEGA-QLSVGAISLAFYNGLW 230
Query: 266 SFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLIL 325
++ G++ +NY E++NP R L +A + + YI +N++YF V+ S+ +
Sbjct: 231 AYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVA 290
Query: 326 VADFFELAFXXXXXXXXXXVLVGLSALGNVMSVIFSQGRIIQQLGREG-VLPFSNFFATS 384
V + + + V S +G F+ GR+I GREG +L ++ +
Sbjct: 291 VTFGDRVLY---PASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVR 347
Query: 385 KPFDSPCVGLFQHFIVCTVTIIAPPAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERK 444
+ +P + + I+ T+ II GD N ++N S+ + GL+ + + RK
Sbjct: 348 RLTPAPAIIFYG--IIATIYII---PGD-INSLVNYFSFAAWLFYGLTILGLIVMRFTRK 401
Query: 445 KGRTMWDPPIKAGIPVIAFFMLANLYLIVAPYIPPSNGESVY 486
+ + PIK + + L +++L++AP I E +Y
Sbjct: 402 E----LERPIKVPVVIPVLMTLISVFLVLAPIISKPTWEYLY 439
>Hs21361563 [E] KOG1287 Amino acid transporters
Length = 511
Score = 131 bits (329), Expect = 3e-30
Identities = 110/435 (25%), Positives = 189/435 (43%), Gaps = 46/435 (10%)
Query: 56 KGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYM 115
K K++ L++ + LI M+G+GIF + S S GL+L++WAVG + ++ G Y+
Sbjct: 32 KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYV 91
Query: 116 EFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADI 175
E GT I ++G Y+ F F+ + + A++ +T AN +
Sbjct: 92 ELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII-------EPTSQAIIAITFANYMV 144
Query: 176 TEW---------NQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWV 226
R + A + IN VK G +Q+I K+ ++ + V G V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204
Query: 227 ALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRT 286
LG G + +F N+FEG+ A I ALY+ ++S+ G+ +NY E+KNP R
Sbjct: 205 RLGQG-----ASTHFENSFEGSSFAVG-DIALALYSALFSYSGWDTLNYVTEEIKNPERN 258
Query: 287 LKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVL 346
L ++ S+ + I+YI N+AY+ V+ + IL +D + F ++
Sbjct: 259 LPLSIGISMPIVTIIYILTNVAYYTVL------DMRDILASDAVAVTFADQIFGIFNWII 312
Query: 347 ---VGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTV 403
V LS G + + I + R+ REG LP + + F +P L + I+ +
Sbjct: 313 PLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERF-TPVPSLLFNGIMALI 371
Query: 404 TIIAPPAGDAYNFVLNLISYPMNIVNFFIS---AGLLWIHWERKKGRTMWDPPIKAGIPV 460
+ + LI+Y FF+ G L++ W+ P+K +
Sbjct: 372 YLCVED-------IFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDR----PRPLKLSVFF 420
Query: 461 IAFFMLANLYLIVAP 475
F L ++L+ P
Sbjct: 421 PIVFCLCTIFLVAVP 435
>HsM4507055 [E] KOG1287 Amino acid transporters
Length = 511
Score = 130 bits (327), Expect = 5e-30
Identities = 110/435 (25%), Positives = 188/435 (42%), Gaps = 46/435 (10%)
Query: 56 KGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYM 115
K K++ L++ + LI M+G+GIF + S S GL+L++WAVG + ++ G Y
Sbjct: 32 KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA 91
Query: 116 EFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADI 175
E GT I ++G Y+ F F+ + + A++ +T AN +
Sbjct: 92 ELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII-------EPTSQAIIAITFANYMV 144
Query: 176 TEW---------NQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWV 226
R + A + IN VK G +Q+I K+ ++ + V G V
Sbjct: 145 QPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV 204
Query: 227 ALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRT 286
LG G + +F N+FEG+ A I ALY+ ++S+ G+ +NY E+KNP R
Sbjct: 205 RLGQG-----ASTHFENSFEGSSFAVG-DIALALYSALFSYSGWDTLNYVTEEIKNPERN 258
Query: 287 LKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVL 346
L ++ S+ + I+YI N+AY+ V+ + IL +D + F ++
Sbjct: 259 LPLSIGISMPIVTIIYILTNVAYYTVL------DMRDILASDAVAVTFADQIFGIFNWII 312
Query: 347 ---VGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTV 403
V LS G + + I + R+ REG LP + + F +P L + I+ +
Sbjct: 313 PLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERF-TPVPSLLFNGIMALI 371
Query: 404 TIIAPPAGDAYNFVLNLISYPMNIVNFFIS---AGLLWIHWERKKGRTMWDPPIKAGIPV 460
+ + LI+Y FF+ G L++ W+ P+K +
Sbjct: 372 YLCVED-------IFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDR----PRPLKLSVFF 420
Query: 461 IAFFMLANLYLIVAP 475
F L ++L+ P
Sbjct: 421 PIVFCLCTIFLVAVP 435
>7294339 [E] KOG1287 Amino acid transporters
Length = 499
Score = 130 bits (327), Expect = 5e-30
Identities = 124/489 (25%), Positives = 217/489 (44%), Gaps = 57/489 (11%)
Query: 32 ANPTGTSDDNRSVETGEHFDVELDKGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSG 91
A P ++ D+ S +G K K++GL+ + +I ++G+GIF + SG
Sbjct: 21 AEPNNSTADSGSQGSGV-------KLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSG 73
Query: 92 SVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGGEKNYLERIF-PAPKFFVTCMYGAYV 150
S+G +LI+W + ++++ G Y E GT IP++GG+ Y+ F P P F +Y
Sbjct: 74 SIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAF----LYLWVA 129
Query: 151 FFLGWAAGNSVNTAVMFLTA------ANADITEWNQRGIGVAVVGFAFLINSVNVKVGLY 204
+ GN++ TA+ F + D + + A++ LIN NVK
Sbjct: 130 LLILVPTGNAI-TALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTR 188
Query: 205 IQNILGIFKIGVVLFIAVTG-WVALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNV 263
+ +I K+ +L I G W G T+++ N F G Y I A Y+
Sbjct: 189 VTDIFTGTKVVALLVIVGAGVWWLFDG------NTEHWDNPFSGGLQDPGY-IALAFYSG 241
Query: 264 IWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVV-PKEVFRTSK 322
++S+ G++ +N+ E+K+P R L A S+ + ++Y+ NIAYF+V+ P E
Sbjct: 242 LFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDE------ 295
Query: 323 LILVADFFELAFXXXXXXXXXXVL---VGLSALGNVMSVIFSQGRIIQQLGREGVLPFSN 379
IL +D + F ++ V S G++ IF+ R+ R G LP
Sbjct: 296 -ILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLP--- 351
Query: 380 FFATSKPFDSPCVGLFQHFIVCTV-TIIAPPAGDAYNFVLNLISYPMNIVNFFISAGLLW 438
A + C+ I V T++ D Y ++N +SY + +GLLW
Sbjct: 352 --AAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVY-VLINYVSYVEALFTLISVSGLLW 408
Query: 439 IHWERKKGRTMWDPPIKAGIPVIAFFMLANLYLIV-----APYIPPSNGESVYQSLPYW- 492
+ +++ K + PIK + + +++ L+L++ PY+ + +P +
Sbjct: 409 MRYKQPK----TERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVYY 464
Query: 493 --IHCVVAW 499
IH V W
Sbjct: 465 LTIHKPVKW 473
>Hs19923170 [E] KOG1287 Amino acid transporters
Length = 507
Score = 130 bits (326), Expect = 7e-30
Identities = 114/441 (25%), Positives = 202/441 (44%), Gaps = 31/441 (7%)
Query: 43 SVETGEHFDVELDKGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAV 102
S GE V L + + L++ + +I ++G+GIF + + +GS GLAL++WA
Sbjct: 35 SAPAGEGEGVTLQRN---ITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAA 91
Query: 103 GAIIALAGLYVYMEFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVN 162
+ ++ G Y E GT I ++GG+ Y+ ++ + F+ ++ L +
Sbjct: 92 CGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLK----LWIELLIIRPSSQYI 147
Query: 163 TAVMFLT------AANADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGV 216
A++F T + E + + V +N +VK +Q+ K+
Sbjct: 148 VALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLA 207
Query: 217 VLFIAVTGWVALGGGLKDGYKTD-NFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNY 275
+ I + G+V +G G D D NF +FEGT IV ALY+ ++++ G++ +N+
Sbjct: 208 LALIILLGFVQIGKG--DVSNLDPNF--SFEGT-KLDVGNIVLALYSGLFAYGGWNYLNF 262
Query: 276 ALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFX 335
E+ NP R L +A SL + +VY+ N+AYF + E +S+ + V DF +
Sbjct: 263 VTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAV-DFGN--YH 319
Query: 336 XXXXXXXXXVLVGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLF 395
V VGLS G+V +F+ R+ REG LP S +P L
Sbjct: 320 LGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP-SILSMIHPQLLTPVPSL- 377
Query: 396 QHFIVCTVTIIAPPAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIK 455
C +T++ + D ++ V+N S+ + G++W+ + + + PIK
Sbjct: 378 --VFTCVMTLLYAFSKDIFS-VINFFSFFNWLCVALAIIGMIWLRHRKPE----LERPIK 430
Query: 456 AGIPVIAFFMLANLYLIVAPY 476
+ + FF+LA L+LI +
Sbjct: 431 VNLALPVFFILACLFLIAVSF 451
>Hs4507053 [E] KOG1287 Amino acid transporters
Length = 515
Score = 127 bits (319), Expect = 5e-29
Identities = 119/480 (24%), Positives = 208/480 (42%), Gaps = 69/480 (14%)
Query: 59 KKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFG 118
K++ L++ + L+ M+G+GIF + + S G++LI+WA+G + ++ G Y E G
Sbjct: 43 KEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELG 102
Query: 119 TAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLG-WAA---GNSVNTAVMFLTAAN-- 172
T I ++G Y+ F G ++ F+ W + A++ +T AN
Sbjct: 103 TTITKSGASYAYILEAF-----------GGFIAFIRLWVSLLVVEPTGQAIIAITFANYI 151
Query: 173 -------ADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGW 225
D R + A + +N VK G +Q+ K+ ++ I V G
Sbjct: 152 IQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGL 211
Query: 226 VALGGGLKDGYKTDNFHNAFEGT----GNATAYGIVNALYNVIWSFVGYSNVNYALGEVK 281
V L G +++F +AFEG+ GN + ALY+ ++S+ G+ +N+ E+K
Sbjct: 212 VKLCQG-----HSEHFQDAFEGSSWDMGNLSL-----ALYSALFSYSGWDTLNFVTEEIK 261
Query: 282 NPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXX 341
NP R L +A S+ + ++YI N+AY+ V+ +S + V F + F
Sbjct: 262 NPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVT-FADQTF--GMFSW 318
Query: 342 XXXVLVGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVC 401
+ V LS G + + IF+ R+ REG LP + F LF C
Sbjct: 319 TIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFN----C 374
Query: 402 TVTIIAPPAGDAYNFVLNLISYPMNIVNFFIS---AGLLWIHWERKKGRTMWDPPIKAGI 458
T+ +I D V LI+Y FF+ G L++ W+ K P+K +
Sbjct: 375 TMALIYLIVED----VFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKR----PRPLKLSV 426
Query: 459 PVIAFFMLANLYLIVAPYIPPSNGESVYQSLPYWIHCVVAWGIFAVGGIYWVVWAVVLPK 518
F + +++L++ P + I+ ++ GI A+ G+ + V LP+
Sbjct: 427 FFPIVFCICSVFLVIVPLFTDT------------INSLIGIGI-ALSGVPFYFMGVYLPE 473
>7297908 [E] KOG1287 Amino acid transporters
Length = 500
Score = 123 bits (308), Expect = 9e-28
Identities = 109/435 (25%), Positives = 197/435 (45%), Gaps = 53/435 (12%)
Query: 59 KKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFG 118
+KL LI+ + +I ++G+GIF + ++ + SVG +L++W I++ G Y E G
Sbjct: 39 RKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCYAELG 98
Query: 119 TAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLG-WAAGNSVNTAVMFLTAAN----- 172
T I R+GG+ YL +G V FL W A + + A +
Sbjct: 99 TCITRSGGDYAYL-----------LVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYA 147
Query: 173 -------ADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGW 225
D + + + + IN ++VKV + +Q++ + K+ ++ I ++G
Sbjct: 148 VKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGL 207
Query: 226 VALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVR 285
+ G + +NF N +EG TA I A Y+ +++F G++ +N+ E+++P +
Sbjct: 208 YYMATG-----ELENFRNPWEGI--YTARNIGYAFYSGLFAFGGWNYLNFVTEELQDPYK 260
Query: 286 TLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVA----DFFELAFXXXXXXX 341
L A ++ + +Y+ VN+AYFAVV K +S + V F LAF
Sbjct: 261 NLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAF------- 313
Query: 342 XXXVLVGLSALGNVMSVIFSQGRIIQQLGREGVLP-FSNFFATSKPFDSPCVGLFQHFIV 400
+ V LS G V V+F+ R+ +EG LP F F + P +
Sbjct: 314 MVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTPIPSL-----IFT 368
Query: 401 CTVTIIAPPAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPV 460
C ++++ + Y LI+Y +++ + A + + W R K R PIK + +
Sbjct: 369 CLMSLLMLLTDNVY----QLINYFSSVLWLSVVASIAGMLWLRHK-RPDLPRPIKVHLAL 423
Query: 461 IAFFMLANLYLIVAP 475
FM++ + L++ P
Sbjct: 424 PITFMVSCVTLVLLP 438
>7301546 [E] KOG1287 Amino acid transporters
Length = 517
Score = 122 bits (306), Expect = 1e-27
Identities = 109/434 (25%), Positives = 198/434 (45%), Gaps = 40/434 (9%)
Query: 59 KKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFG 118
K+LGL+ + +I + G+GIF + SVG +L++W + ++++ G Y E G
Sbjct: 57 KQLGLLEGVAIILGIIFGSGIFVSPKGVIREVESVGASLVIWVLCGLLSMIGALCYAELG 116
Query: 119 TAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAAN------ 172
TAIP++GG+ Y+ + + F+ ++ A + F+ A+M LT A+
Sbjct: 117 TAIPKSGGDYAYIFEAYGSLPAFL-YLWDAMMIFV------PTTNAIMGLTFASYVLEPF 169
Query: 173 ----ADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTG--WV 226
+I + + + + F +NS +KV +QN++ KI ++ I + G W+
Sbjct: 170 FGGACEIPKIALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVLIILVGLVWM 229
Query: 227 ALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRT 286
+G +NF F+ T V A Y+ I+S+ G++ +N+ E+++P R
Sbjct: 230 MMG-------NVENFTRPFDNTETDPGKMSV-AFYSGIFSYAGWNYLNFMTEELRDPYRN 281
Query: 287 LKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVL 346
L A SL + +Y+ N+AY AV+ S I V ++ ++
Sbjct: 282 LPRAIYISLPLVTGIYVLANVAYLAVLSPSEMIASNAIAVTFGDKI---LGVFSLIIPLM 338
Query: 347 VGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTII 406
V +SA G + I + RI R G +P + K + +P L +C ++I+
Sbjct: 339 VAISAFGGLSVHIMTSSRICFVGARNGHMPAILSHISVKSY-TPLPSL---VFLCFLSIV 394
Query: 407 APPAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFML 466
D Y LI+Y + +FFI + + + R R + PIK + + A F++
Sbjct: 395 MLVVSDVY----VLITYASIVESFFIMLSVSAVLYFRYT-RPCMERPIKVAMWIPALFVI 449
Query: 467 ANLYLIVAP-YIPP 479
+L+V P Y+ P
Sbjct: 450 VCAFLVVVPIYVAP 463
>Hs7657683 [E] KOG1287 Amino acid transporters
Length = 501
Score = 119 bits (299), Expect = 1e-26
Identities = 104/432 (24%), Positives = 189/432 (43%), Gaps = 52/432 (12%)
Query: 59 KKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFG 118
+K+ L+ + +I ++G GIF + +GSVG++L +W V +++L G Y E G
Sbjct: 42 RKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVLSLFGALSYAELG 101
Query: 119 TAIPRNGGEKNYLERIF-----------------PAPKFFVTCMYGAYVFFLGWAAGNSV 161
T I ++GG Y+ +F PA ++ +G Y+ +
Sbjct: 102 TTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCEIP 161
Query: 162 NTAVMFLTAANADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIA 221
A+ +TA +G+ VV ++NS++V IQ L K+ +L I
Sbjct: 162 ELAIKLITA------------VGITVV---MVLNSMSVSWSARIQIFLTFCKLTAILIII 206
Query: 222 VTGWVALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVK 281
V G + L G +T NF +AF G +++ + A Y ++++ G+ +N+ EV+
Sbjct: 207 VPGVMQLIKG-----QTQNFKDAFSGR-DSSITRLPLAFYYGMYAYAGWFYLNFVTEEVE 260
Query: 282 NPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXX 341
NP +T+ +A S+ + I Y+ N+AYF + E S + V L
Sbjct: 261 NPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERL---LGNFSL 317
Query: 342 XXXVLVGLSALGNVMSVIFSQGRIIQQLGREGVLP-FSNFFATSKPFDSPCVGLFQHFIV 400
+ V LS G++ +F+ R+ REG LP + K P V ++
Sbjct: 318 AVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAV-----IVL 372
Query: 401 CTVTIIAPPAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPV 460
+T+I +GD + +LN +S+ + AGL+++ ++ P K + +
Sbjct: 373 HPLTMIMLFSGD-LDSLLNFLSFARWLFIGLAVAGLIYLRYKCPD----MHRPFKVPLFI 427
Query: 461 IAFFMLANLYLI 472
A F L+++
Sbjct: 428 PALFSFTCLFMV 439
>CE22438 [E] KOG1287 Amino acid transporters
Length = 541
Score = 118 bits (296), Expect = 2e-26
Identities = 112/434 (25%), Positives = 191/434 (43%), Gaps = 39/434 (8%)
Query: 60 KLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGT 119
++GL SC+ + ++G GIF T+ L+ + G+AL++W +I+L G Y+E GT
Sbjct: 19 QMGLWSCMSYVIANIIGAGIFITPGTVLKLALTNGMALVVWLGCGLISLIGGICYIELGT 78
Query: 120 AIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADITEWN 179
+I G + Y + F G + F AA + T ++ A + I W+
Sbjct: 79 SIRDPGCDFAYNVYVGWEGIAFSFMWVGVIMSFPASAAVQA-QTFGQYIVAGLSPI--WH 135
Query: 180 ---------QRGIGVAVVGFAFLINSVNV-KVGLYIQNILGIFKIGVVLFIAVTG-WVAL 228
+RG+G A++ ++N + K Q + I K+ + I VTG W +
Sbjct: 136 LGSPYDVILERGLGFALIIILTVLNLYAIDKYASKFQIFVTIAKLLSLAIIIVTGFWYLI 195
Query: 229 GGGLKDGYKTDNFHNAFEGTGNATAYGIVN---ALYNVIWSFVGYSNVNYALGEVKNPVR 285
G +T++F +AF N Y I A Y +WSF G+ +NY E+KNP R
Sbjct: 196 VKG-----ETEHFKDAFTPLPNEK-YDIGQISLAFYGALWSFAGWDILNYGTPEIKNPRR 249
Query: 286 TLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXV 345
T+ IA + + +VY+ +N++Y V+ E + S + ADF +
Sbjct: 250 TMPIALLGGISAVTLVYMAMNVSYMTVLDTETLKNSSAV-AADFARITL--GDFSYAIPF 306
Query: 346 LVGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTI 405
++ + +G + S IF R REG LP ++ LFQ ++CT+ +
Sbjct: 307 MISILLIGTLNSNIFCGSRFTHAAAREGHLPTFLSCINAESNSPRAALLFQ--LICTIAV 364
Query: 406 IAPPAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVI--AF 463
++ +++ M F A LLWI + R + P +P+I
Sbjct: 365 TFVDT----ESLITYVTFVMFGQRVFTMAALLWIRY-----RNIPVHPDAIRVPLIFSIL 415
Query: 464 FMLANLYLIVAPYI 477
F + + L+V P+I
Sbjct: 416 FFMITIALVVTPFI 429
>CE03266 [E] KOG1287 Amino acid transporters
Length = 493
Score = 116 bits (291), Expect = 8e-26
Identities = 115/456 (25%), Positives = 205/456 (44%), Gaps = 38/456 (8%)
Query: 59 KKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFG 118
K L L + + +I ++G+GIF + + +GSVGL+LI+W + I G Y Y E G
Sbjct: 30 KSLTLFNGVSMIVGCIIGSGIFVSPTGVQEQAGSVGLSLIVWLISGIFTAIGAYCYAELG 89
Query: 119 TAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAV-----MFLTAANA 173
T I ++GG+ Y+ F F+ A V ++ A+ F A
Sbjct: 90 TLIKKSGGDYAYIMEAFGPFVAFIRLWIEAIVVRPCTVTIVALTFAIYGLRPFFPDCAPP 149
Query: 174 DITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLK 233
D+ + + ++ IN ++V++ +Q+ I K+ + I +TG L G +
Sbjct: 150 DVV---AELLAILLIVLMTAINCISVRLATIVQDWFTIAKVVALCLIILTGLGLLFFG-E 205
Query: 234 DGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPT 293
YK D+F N FE T + A Y+ ++++ G++ +N+ + E++NP R L +A
Sbjct: 206 SQYK-DSFENIFENTSQDFT-KVSLAFYSGLFAYSGWNFLNFIVEELQNPKRNLPLAIAI 263
Query: 294 SLIFLAIVYIFVNIA-YFAVVPKEVFRTSKL-ILVAD--FFELAFXXXXXXXXXXVLVGL 349
S+ ++Y+ N+A Y A+ P E+ + + +L A+ + + AF + V
Sbjct: 264 SITSCTVIYVLTNVALYTAISPDEMLESPAVAVLFANKLYGKFAF-------IMPLCVAC 316
Query: 350 SALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPP 409
S +G+ VIF+ R+ REG +P + +K +P + + ++A
Sbjct: 317 STIGSANGVIFTSARLFYSGAREGQMP-AVLTMINKKTKTPIPAVILTGALSIAYLLA-- 373
Query: 410 AGDAYNFVLNL-ISYPMNIVNFFISAGLLWIHWERKKGRTMWDP--PIKAGIPVIAFFML 466
+ D Y + + ISY + I A L W+ RTM D PIK + A F+
Sbjct: 374 SKDVYQLINYIQISYWLAIGTAI--AALFWLR------RTMPDASRPIKVPLIWPAIFLA 425
Query: 467 ANLYLIVAPYIPPSNGESVYQSLPYWIHCVVAWGIF 502
+ L++ P + + L + V +GIF
Sbjct: 426 GCIALVLIPMVAAPRDTGI--GLLIMLSAVPVYGIF 459
>CE28440 [E] KOG1287 Amino acid transporters
Length = 493
Score = 113 bits (282), Expect = 9e-25
Identities = 107/441 (24%), Positives = 205/441 (46%), Gaps = 28/441 (6%)
Query: 46 TGEHFDVEL-DKGSKK-LGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVG 103
+ EH D E+ DKG +K + L + + +I ++G+GIF + I +GSVGL+LI+W +
Sbjct: 15 SNEHHDEEVGDKGLEKTMTLFNGVSIIVGCIIGSGIFISPTGIQAQAGSVGLSLIVWVLS 74
Query: 104 AIIALAGLYVYMEFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNT 163
+ A G + Y E GT I ++GG+ Y+ F F+ + V A ++
Sbjct: 75 GLFAGIGAFCYAELGTLIRKSGGDYAYIMEAFGPFLAFLRLWIESIVVRPCTATIVALTF 134
Query: 164 AVMFLTA--ANADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIA 221
A+ L + D + I ++ +N ++VK +Q+ + K ++ I
Sbjct: 135 AIYMLKPFYPDCDSPPLSTELIAALLLVLLTAVNCISVKWASKVQDFFFVTKTAALVLII 194
Query: 222 VTGWVALGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVK 281
TG + G + + D+F N FE T + A Y+ ++++ G++ +N+ + E++
Sbjct: 195 FTGLWNMVSGKPEAF--DSFENIFENTAKDLETASL-AFYSGLFAYQGWNYLNFIVEELQ 251
Query: 282 NPVRTLKIAGPTSLIFLAIVYIFVNIA-YFAVVPKEVFRTSKLILVADFFELAFXXXXXX 340
NP R L ++ S I+Y N+A Y ++ P E+ + + ++ F E +
Sbjct: 252 NPKRNLPLSIAISCSLCTIIYTLTNVALYTSITPDEMLASPAVAVL--FAEKNY--GWFA 307
Query: 341 XXXXVLVGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIV 400
+ V S +G+ VI + R+ REG +P + +K +P + ++
Sbjct: 308 FCMPIFVACSTIGSANGVILTSSRLFYCGAREGQMP-NVLTMVNKTTKTPIPAVILTGLL 366
Query: 401 CTVTIIAPPAGDAYNFVLNLISYPMNIVNFFISAG--LLWIHWERKKGRTMWDPP--IKA 456
+ ++ N + +LI+Y V+++I+ G +L + + RK TM D P +KA
Sbjct: 367 SLLYLLLS------NNIYSLINYIQ--VSYWIAIGGAILALFYFRK---TMPDAPRAVKA 415
Query: 457 GIPVIAFFMLANLYLIVAPYI 477
I F + + L++ P +
Sbjct: 416 PIVFPIIFFIGCVLLVLVPVL 436
>Hs6912670 [E] KOG1287 Amino acid transporters
Length = 535
Score = 108 bits (269), Expect = 3e-23
Identities = 101/421 (23%), Positives = 173/421 (40%), Gaps = 25/421 (5%)
Query: 59 KKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFG 118
K++GL+S G+I ++G+GIF + +GSVGLALI+W V I + G Y E G
Sbjct: 38 KEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELG 97
Query: 119 TAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADITEW 178
IP++GG+ +Y++ IF F+ V + N AV+ LT +N +
Sbjct: 98 VTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIY-------PTNQAVIALTFSNYVLQPL 150
Query: 179 ------NQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGL 232
+ G+ + L+ VN + + IF G +L +A+ + +
Sbjct: 151 FPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQIC 210
Query: 233 KDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGP 292
K Y NAFE + A +++ G++ +NY E+ +P + L A
Sbjct: 211 KGEYFWLEPKNAFEDFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIF 270
Query: 293 TSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSAL 352
S+ + VY+F N+AY + + S + V +L + V LS
Sbjct: 271 ISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKL---LGVMAWIMPISVALSTF 327
Query: 353 GNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPPAGD 412
G V +F+ R+ REG LP K C + C T++ D
Sbjct: 328 GGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVK----RCTPIPALLFTCISTLLMLVTSD 383
Query: 413 AYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLANLYLI 472
Y ++N + + + AG + + W++ PIK + ++L +L+
Sbjct: 384 MYT-LINYVGFINYLFYGGTVAGQIVLRWKKPD----IPRPIKINLLFPIIYLLFWAFLL 438
Query: 473 V 473
V
Sbjct: 439 V 439
>7292991 [E] KOG1287 Amino acid transporters
Length = 445
Score = 107 bits (267), Expect = 5e-23
Identities = 101/426 (23%), Positives = 183/426 (42%), Gaps = 36/426 (8%)
Query: 74 MLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGGEKNY-LE 132
M+G+GIF S + +GSVG++ I+W +++L G Y E GT +G E Y ++
Sbjct: 1 MIGSGIFVSPSGLLVRTGSVGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMD 60
Query: 133 RIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLT-AANADITEWNQ-RGIG-----V 185
PAP F + +V L + F A A +TE + RG+ V
Sbjct: 61 AYGPAPAFLFS-----WVSTLVLKPSQMAIICLSFAQYAVEAFVTECDPPRGVVKMVALV 115
Query: 186 AVVGFAFLINSVNVKVGLYIQNILGIFK-IGVVLFIAVTGWVALGGGLKDGYKTDNFHNA 244
A+V F +N +V +G+ +QN+ K + VV+ I W + G T + NA
Sbjct: 116 AIVMILF-VNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQGN------TQHLSNA 168
Query: 245 FEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIF 304
F G I A Y +W++ G++N+NY E+KNP + L + + + + Y
Sbjct: 169 FNGP-MPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYAL 227
Query: 305 VNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNVMSVIFSQGR 364
+NI+Y A + + S+ + V + + V +S G+ +F+ GR
Sbjct: 228 INISYLAAMSPQEMIESEAVAVTFGNRI---LGALAWLMPLSVTISTFGSANGTLFAAGR 284
Query: 365 IIQQLGREG-VLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPPAGDAYNFVLNLISY 423
+ REG +L ++ + +P GL H ++ + ++ + + +LI +
Sbjct: 285 LCFAASREGHLLDILSYVHVRRL--TPAPGLIFHSLIASAMVL-------HGTIDSLIDF 335
Query: 424 PMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLANLYLIVAPYIPPSNGE 483
+ + G + + + + P K I + ++ ++YL+ AP E
Sbjct: 336 -FSFTAWIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVE 394
Query: 484 SVYQSL 489
+Y L
Sbjct: 395 YLYALL 400
>CE07491 [E] KOG1287 Amino acid transporters
Length = 562
Score = 107 bits (266), Expect = 6e-23
Identities = 111/412 (26%), Positives = 188/412 (44%), Gaps = 30/412 (7%)
Query: 74 MLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGGEKNYLER 133
++G GIF I + S GLAL++W +I+L G Y+E GT+I G + Y
Sbjct: 50 IIGAGIFITPGPILQYTFSNGLALLVWIGCGLISLIGGICYIELGTSIHDPGCDFAYTVY 109
Query: 134 IFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADITEWN---QRGIGVAVVGF 190
+ F G + F AA ++ T V + W+ ++G+G A++
Sbjct: 110 VGWEGIAFSFMWVGVIMSFPASAAVQAL-TFVAGMAPIWPLEHPWDGIIEKGLGFALIIV 168
Query: 191 AFLINSVNV-KVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLKDGYKTDNFHNAFEGTG 249
++N + K Q ++ I K+ + I VTG+ L + G +T+ + FEG+
Sbjct: 169 LTILNLYAIDKYASKFQIVVTIAKMLSLAIIIVTGFYYL---IFKG-QTEYLEHPFEGS- 223
Query: 250 NATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAY 309
N I A Y +WSF G+ +N+ E++NP RT+ IA + + VY+ +NI+Y
Sbjct: 224 NTNPGQISLAFYGALWSFAGWDILNFGTPEIRNPRRTMPIALLGGVSIVTAVYLAMNISY 283
Query: 310 FAVV-PKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNVMSVIFSQGRIIQQ 368
V+ P ++ ++ + ADF ++ ++ L +G + S IF R
Sbjct: 284 MTVLTPGQIMNST--AVAADFAQITL--GGFSYAIPFMIALLLIGTLNSNIFCGSRFTHA 339
Query: 369 LGREGVLPFSNFFATSKPFDSPCVG-LFQHFIVCTVTIIAPPAGDAYNFVLNLISYPMNI 427
REG LP + ++ +SP LFQ +VCTV + N ++N +S+ M
Sbjct: 340 AAREGHLP-TFLSCINEESNSPRAALLFQ--LVCTVVVTFIDT----NSLINYVSFVMFG 392
Query: 428 VNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFM--LANLYLIVAPYI 477
F L+WI + R + P +P+I F+ L + L+V P+I
Sbjct: 393 QRVFTMTALMWIRY-----RNIPVHPDAIRVPLIFSFLFWLITIALVVVPFI 439
>Hs9790235 [E] KOG1287 Amino acid transporters
Length = 523
Score = 105 bits (262), Expect = 2e-22
Identities = 105/425 (24%), Positives = 176/425 (40%), Gaps = 25/425 (5%)
Query: 59 KKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFG 118
K++GL+S +I ++G+GIF + SGSVGLAL +W +G + G Y E G
Sbjct: 38 KEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELG 97
Query: 119 TAIPRNGGEKNYLERIFPAPKFF------VTCMYGAYVFFLGWAAGNSVNTAVMFLTAAN 172
AIP++GG+ Y+ IF F V MY + + N V V N
Sbjct: 98 VAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVF----PN 153
Query: 173 ADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGL 232
R + +A + +NS +V+ IQ+ +F G +L +++ V L
Sbjct: 154 CIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQD---MFTGGKLLALSLIIGVGLLQIF 210
Query: 233 KDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGP 292
+ ++ NAF + + A ++F G++ +NY E+ + + L A
Sbjct: 211 QGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIF 270
Query: 293 TSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSAL 352
S+ + VY F NIAYF + + +S + V +L V V LS
Sbjct: 271 ISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKL---LGYFSWVMPVSVALSTF 327
Query: 353 GNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPPAGD 412
G + +F+ R+ REG LP + C + + C T + GD
Sbjct: 328 GGINGYLFTYSRLCFSGAREGHLP----SLLAMIHVRHCTPIPALLVCCGATAVIMLVGD 383
Query: 413 AYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLANLYLI 472
Y ++N +S+ + GLL + W R PIK + + +++ +L+
Sbjct: 384 TYT-LINYVSFINYLCYGVTILGLLLLRWR----RPALHRPIKVNLLIPVAYLVFWAFLL 438
Query: 473 VAPYI 477
V +I
Sbjct: 439 VFSFI 443
>CE07028 [E] KOG1287 Amino acid transporters
Length = 464
Score = 105 bits (262), Expect = 2e-22
Identities = 116/457 (25%), Positives = 196/457 (42%), Gaps = 59/457 (12%)
Query: 45 ETGEHFDVELDKGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGA 104
E E + K ++ L + +I ++G+GIF + +GS G++L++W +
Sbjct: 3 EKEEEVSLNQIKLKPRISLFNGCTIIIGVIIGSGIFVSPKGVLLEAGSAGMSLLIWLLSG 62
Query: 105 IIALAGLYVYMEFGTAIPRNGGEKNYLERIF-PAPKFFVTCMYGAYVFFLGWAAGNSVNT 163
+ A+ G Y E GT IP++GG+ Y+ F P P F ++ A V N +
Sbjct: 63 VFAMIGAVCYSELGTLIPKSGGDYAYIYEAFGPLPSFLF--LWVALVII------NPTSL 114
Query: 164 AVMFLTAAN-----------ADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIF 212
A++ +T A D+ G +AV+ F IN +V++ + I
Sbjct: 115 AIIAITCATYALQPFYSCPVPDVVVNLFAGCIIAVLTF---INCWDVRMATRTNDFFTIT 171
Query: 213 KIGVVLFIAVTG--WVALGGGLKDGYKTDNFHNAFEGTGNATAY-GIVNALYNVIWSFVG 269
K+ + I G W++LG DN G+ T I A Y+ ++SF G
Sbjct: 172 KLIALTLIITCGGYWLSLG-------HIDNLVMPDVAEGSQTKLSAIAMAFYSGVFSFSG 224
Query: 270 YSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADF 329
+S +N+ E+KNP R L A S+ + IVY+ VNIAYF+V+ T IL +D
Sbjct: 225 FSYLNFVTEELKNPFRNLPRAIYISIPIVTIVYMLVNIAYFSVL------TVDEILDSDA 278
Query: 330 FELAFXXXXXXXXXXVLVGLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDS 389
+ F ++G +M ++F G R LP F S +
Sbjct: 279 VAITFADK--------ILGTFGSKILMPLMFFSG------ARNSQLP-ELFAMISIRQLT 323
Query: 390 PCVGLFQHFIVCTVTIIAPPAGDAYNFVLNLISYPMNIVNFFISAGLLWIHWERKKGRTM 449
P L + +I+ G+ + ++N +S+ ++V F AGLL + + + +
Sbjct: 324 PIPSL---IFLGGTSIVMLFIGNVFQ-LINYLSFAESLVVFSSVAGLLKLRFTMPE-NVL 378
Query: 450 WDPPIKAGIPVIAFFMLANLYLIVAPYIPPSNGESVY 486
PIK + F L L+L++ P+ E +Y
Sbjct: 379 NARPIKISLLWPILFFLMCLFLLILPFFHSDPWELIY 415
>CE27888 [E] KOG1287 Amino acid transporters
Length = 550
Score = 101 bits (251), Expect = 4e-21
Identities = 84/356 (23%), Positives = 154/356 (42%), Gaps = 22/356 (6%)
Query: 58 SKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEF 117
S K+G + + ++G+GIF ++I S+GL+L++W + A+IA+ G Y+E
Sbjct: 33 SHKMGFLGATSYVIGNIIGSGIFITPASILRNVDSIGLSLLIWVLCAVIAILGAICYIEL 92
Query: 118 GTAIPRNGGEKNYLERI------FPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAA 171
GT+I G + Y+ + F V Y A + G + +
Sbjct: 93 GTSIREAGCDFAYICYVKWYSIAFAFMWVSVLMTYPATIAICAETFGQYLIEGLKQYYEI 152
Query: 172 NADITEWNQRGIGVAVVGFAFLINSVNV----KVGLYIQNILGIFKIGVVLFIAVTGWVA 227
+ + Q+ +++ FL+ +N K Q + I K+ + I TG+
Sbjct: 153 DDALVPTCQKLFAYSLL---FLVTWMNFFELSKFAARFQILATIAKLFSCMLIIGTGFYF 209
Query: 228 LGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTL 287
GY + + GTGN ++ Y +W+F G+ +NY+ GE+K+P R +
Sbjct: 210 YFVKGWHGYLENPMQGSKYGTGN-----LILGFYGGLWAFSGWDVLNYSTGEIKHPKRNV 264
Query: 288 KIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLV 347
A T + + +Y+ +N+AYF V+ E + S + E L+
Sbjct: 265 PFALLTGISVVTAIYVAINVAYFVVLDVETVKQSDAVAAIFSRE---TLGDFANVVPFLI 321
Query: 348 GLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTV 403
G+ +G++ S +FS R + R+G LP + F + +SP V + ++ V
Sbjct: 322 GILLIGSLNSNLFSGSRYMYAAARQGHLP-ACFSCVNTETESPRVAVLAQSVLALV 376
>CE09028 [E] KOG1287 Amino acid transporters
Length = 566
Score = 101 bits (251), Expect = 4e-21
Identities = 84/356 (23%), Positives = 154/356 (42%), Gaps = 22/356 (6%)
Query: 58 SKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEF 117
S K+G + + ++G+GIF ++I S+GL+L++W + A+IA+ G Y+E
Sbjct: 33 SHKMGFLGATSYVIGNIIGSGIFITPASILRNVDSIGLSLLIWVLCAVIAILGAICYIEL 92
Query: 118 GTAIPRNGGEKNYLERI------FPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAA 171
GT+I G + Y+ + F V Y A + G + +
Sbjct: 93 GTSIREAGCDFAYICYVKWYSIAFAFMWVSVLMTYPATIAICAETFGQYLIEGLKQYYEI 152
Query: 172 NADITEWNQRGIGVAVVGFAFLINSVNV----KVGLYIQNILGIFKIGVVLFIAVTGWVA 227
+ + Q+ +++ FL+ +N K Q + I K+ + I TG+
Sbjct: 153 DDALVPTCQKLFAYSLL---FLVTWMNFFELSKFAARFQILATIAKLFSCMLIIGTGFYF 209
Query: 228 LGGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTL 287
GY + + GTGN ++ Y +W+F G+ +NY+ GE+K+P R +
Sbjct: 210 YFVKGWHGYLENPMQGSKYGTGN-----LILGFYGGLWAFSGWDVLNYSTGEIKHPKRNV 264
Query: 288 KIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLV 347
A T + + +Y+ +N+AYF V+ E + S + E L+
Sbjct: 265 PFALLTGISVVTAIYVAINVAYFVVLDVETVKQSDAVAAIFSRE---TLGDFANVVPFLI 321
Query: 348 GLSALGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTV 403
G+ +G++ S +FS R + R+G LP + F + +SP V + ++ V
Sbjct: 322 GILLIGSLNSNLFSGSRYMYAAARQGHLP-ACFSCVNTETESPRVAVLAQSVLALV 376
>7302046 [E] KOG1287 Amino acid transporters
Length = 505
Score = 100 bits (248), Expect = 8e-21
Identities = 79/320 (24%), Positives = 146/320 (44%), Gaps = 15/320 (4%)
Query: 60 KLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGT 119
K+ L++ +I ++G+GIF + + +GSV LALI+W + + ++ G Y Y E GT
Sbjct: 48 KMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMVGAYCYAELGT 107
Query: 120 AIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADIT--E 177
I ++G + Y+ F F+ + A ++ + L + T E
Sbjct: 108 MITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPE 167
Query: 178 WNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLKDGYK 237
+ R + V + LIN +VK +Q+I K+ + I TG L Y
Sbjct: 168 DSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQL-------YL 220
Query: 238 TDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIF 297
+ + FE T + I + Y+ ++++ G++ +N+ + E+K+PV+ L A S
Sbjct: 221 GNTQYFTFENT-DTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTL 279
Query: 298 LAIVYIFVNIAYFAVV-PKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNVM 356
+ IVY+ N++++ ++ P EV +S + + + E AF V V LS G V
Sbjct: 280 VTIVYVMANVSFYTILSPDEVMGSSAVAVT--YAERAF--GMLAWTIPVFVALSTFGAVN 335
Query: 357 SVIFSQGRIIQQLGREGVLP 376
++ + R+ G +P
Sbjct: 336 GILLTSSRLFYAGANNGQMP 355
>Hs20270383 [E] KOG1287 Amino acid transporters
Length = 470
Score = 94.0 bits (232), Expect = 6e-19
Identities = 95/423 (22%), Positives = 184/423 (43%), Gaps = 34/423 (8%)
Query: 74 MLGTGIFAVSSTIYTLSG-SVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGGEKNYLE 132
++G GIF + S +VG++L +WA AI+A+ E + P +G + +L+
Sbjct: 26 IIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSAEISISFPCSGAQYYFLK 85
Query: 133 RIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTA--ANADITEWNQRGIGVAVVGF 190
R F + F+ ++ + G AG ++ A + + + + ++ + +A++
Sbjct: 86 RYFGSTVAFLN-LWTSLFLGSGVVAGQALLLAEYSIQPFFPSCSVPKLPKKCLALAMLWI 144
Query: 191 AFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLKDGYKTDNFHNAFEGTGN 250
++ S VK ++Q + K+ ++ FI++TG V L G K+ + F NAF+
Sbjct: 145 VGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKKEN--VERFQNAFDAELP 202
Query: 251 ATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYF 310
++ ++ A++ +++ G + GE+K P T+ T+L + +VY+ VNI+Y
Sbjct: 203 DISH-LIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALPLMTVVYLLVNISYL 261
Query: 311 AVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVL---VGLSALGNVMSVIFSQGRIIQ 367
V+ T + IL +D + + ++ + S N++ IF R I
Sbjct: 262 TVL------TPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISIFKSSRPIY 315
Query: 368 QLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPPAGDAYNFVLNLISYPMNI 427
+EG LP F T SP + + ++ II D ++N I + ++
Sbjct: 316 LASQEGQLPL--LFNTLNSHSSPFTAVLLLVTLGSLAIILTSLID----LINYIFFTGSL 369
Query: 428 VNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLANLY----LIVAPYIPPSNGE 483
+ + G+L R +P + V F LA + L+V P + N
Sbjct: 370 WSILLMIGIL--------RRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVH 421
Query: 484 SVY 486
VY
Sbjct: 422 YVY 424
>CE17028 [E] KOG1287 Amino acid transporters
Length = 521
Score = 83.2 bits (204), Expect = 1e-15
Identities = 121/532 (22%), Positives = 214/532 (39%), Gaps = 98/532 (18%)
Query: 56 KGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYM 115
K K+GLI I ++G+GIF I +GSVGL+LI+W A++ + Y+
Sbjct: 4 KEDNKIGLIGATSYIVGSIIGSGIFIAPKGIVEHAGSVGLSLIIWVFCALLNMITAINYI 63
Query: 116 EFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLT------ 169
E GT+IP +G + Y++ + P F + +L +S + AV++LT
Sbjct: 64 ELGTSIPESGADLAYIDYMGWTPIAF-------SLLWLSLLIQSSSSAAVLYLTFGKYLV 116
Query: 170 AANADITEWNQRGIG--VAVVGFA---------------FLINS----VNVKVGLYIQNI 208
A I + G + GF FLI + V L + N+
Sbjct: 117 QALEPIVCFTSSGADNCAKLFGFGLLCKFFWKLRKPLDNFLIRKPFLIIIFTVFLTLTNM 176
Query: 209 LGIFK--------------IGVVLFIAVTGWVALGGGLKDGYKTDNFHNAFEGTGNATAY 254
+ K ++ I + + + G Y++ + A A
Sbjct: 177 FSLNKFAARVQIISMCSKIFATLIIIGIGFFFIIFRGATSHYRSSEIMKGSDWNAGAIAL 236
Query: 255 GIVNALYNVIWSFVGYSNVNYALGE--VKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFAV 312
A+Y W+F G++ +NY E ++N +TL A L+ A++Y+ VN++YFA+
Sbjct: 237 ----AIYQGNWAFGGFTTLNYGTEEIQIENFRKTLPRACLGGLLISAVIYVLVNVSYFAI 292
Query: 313 V-PKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALG------------NVMSVI 359
+ P+E+ +S VA F +VG +G + S +
Sbjct: 293 LTPQEIIDSS---AVATTFIQRTVGNGPAFAVPAVVGFLLVGTLNGDVPIKNFKTLTSDM 349
Query: 360 FSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPPAGDAYNFVLN 419
R + R ++P + F DSP V +F H + +II GD V +
Sbjct: 350 TQFCRYMVAGSRRKMMP-TCFSLIHVDNDSPRVSVFFHTL---TSIIFAFMGDTDQLV-D 404
Query: 420 LISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLANLYLIVAPYIPP 479
++ + F L+ I W K + P+K I F+ + NL +++A + P
Sbjct: 405 YLTVTGMLTTIFALLVLVIIKW---KKMPIASDPVKYSI----FWPILNLVIMIALLVIP 457
Query: 480 SNGESVYQSLPYWIHCVVAWGIFAVGGIYWVVWAVVLPKIGKYELVHEEVLG 531
+ + ++ + +F +GG+ VV+ ++ K+ + H E LG
Sbjct: 458 IQQDP--------LSSIIGFSMF-LGGV--VVYFII-----KFVVSHTEFLG 493
>CE06416 [E] KOG1287 Amino acid transporters
Length = 440
Score = 82.0 bits (201), Expect = 2e-15
Identities = 80/343 (23%), Positives = 162/343 (46%), Gaps = 25/343 (7%)
Query: 137 APKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADITE--WNQRGIGVAVVGFAFLI 194
A + V + G+ +F + +VN+ + D T W ++ +G +++ +
Sbjct: 15 AISYIVGNIVGSGIFITPTSIIENVNSIQIQGAGVELDETSEFWAKKLLGFSLIILLMFM 74
Query: 195 NSVNVKVGLYIQNILG-IFKIGVVLFIAVTGWVALGGGLKDGYKTDNFHNAFEGTGNATA 253
N ++K + +IL + KI L I +TG+ L + +K N F+G+ N
Sbjct: 75 NFFSLKTFVQRFSILASLAKIAATLLIIITGFYYL---IFKHWK-QNLEEPFKGS-NWNP 129
Query: 254 YGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVV 313
VNAL+ ++S+ G+ +N+ E++NP RT+ ++ + + ++Y+ VN+AY V+
Sbjct: 130 GPFVNALFAGLFSYDGWDILNFGAEEIENPKRTMPLSIIIGMTCIGVIYVAVNVAYSIVL 189
Query: 314 -PKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNVMSVIFSQGRIIQQLGRE 372
P E+ ++ + + DF V+V + +G++ S +FS R +Q + R+
Sbjct: 190 SPTEMIASNAVAI--DFANKTL--GAAAFVVPVMVAILLIGSLNSTMFSASRYLQAVSRQ 245
Query: 373 GVLPFSNFFATSKPFDSPCVGLFQHFIVC-TVTIIAPPAGDAYNFVLNLISYPMNIVNFF 431
G +P S + DSP V L H ++ V+ + P + ++N +++ F
Sbjct: 246 GHIP-SAISGIAPNCDSPRVALLVHILIAIAVSFLGDP-----DKLINYVAFAQWSQRAF 299
Query: 432 ISAGLLWIHWERKKGRTMWDPPIKAGI--PVIAFFMLANLYLI 472
+ LL++ R +GR I+ I P++ F + ++ +I
Sbjct: 300 TMSALLYL---RIRGRPRHPDRIQLPIIMPILFFLVCTSMVVI 339
>At5g04770 [E] KOG1286 Amino acid transporters
Length = 583
Score = 77.4 bits (189), Expect = 5e-14
Identities = 99/454 (21%), Positives = 174/454 (37%), Gaps = 41/454 (9%)
Query: 2 SGSRSFLSQLNVFNKDNYEISTDSKTLDTDANPTGTSDDNRSVETGEHFDVELDKGSKKL 61
+G S S L V+ +S L A TS D S V ++ + L
Sbjct: 9 NGGHSSFSSLRVYLNS---LSATPSRLSRRAISVSTSSDEMSRVRA----VSGEQMRRTL 61
Query: 62 GLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAI 121
IGL M+G G+F + L + ++ +A+ + AL + Y EF +
Sbjct: 62 RWYDLIGLGIGGMVGAGVFVTTGRASRLDAGPSI-VVSYAIAGLCALLSAFCYTEFAVHL 120
Query: 122 PRNGGEKNYLERIFPA-PKFFV------------TCMYGAYVFFLGWAAGNSVNTAVMFL 168
P GG +Y+ F P FF + ++ +LG A G S + +
Sbjct: 121 PVAGGAFSYIRITFGEFPAFFTGANLVMDYVMSNAAVSRSFTAYLGTAFGISTSKWRFVV 180
Query: 169 TAANADITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVAL 228
+ E + + V VV +I + + + I+ F I + F+ V G++
Sbjct: 181 SGLPKGFNEIDP--VAVLVVLVITVIICCSTRESSKVNMIMTAFHIAFIFFVIVMGFIKG 238
Query: 229 GGGLKDGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLK 288
+ F G A G+ N V S++GY V+ EV+NPV+ +
Sbjct: 239 DSKNLSSPANPEHPSGFFPFGAA---GVFNGAAMVYLSYIGYDAVSTMAEEVENPVKDIP 295
Query: 289 IAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVG 348
+ S+ + ++Y + ++ ++P + LI F AF +VG
Sbjct: 296 VGVSGSVAIVTVLYCLMAVSMSMLLPYD------LIDPEAPFSAAFRGSNGWEWVTKVVG 349
Query: 349 LSA----LGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVT 404
+ A L +++ + Q R + +GR V+PF +FA P S V + T
Sbjct: 350 IGASFGILTSLLVAMLGQARYMCVIGRSRVVPF--WFAKIHPKTSTPVNASTFLGIFTAA 407
Query: 405 IIAPPAGDAYNFVLNLISYPMNIVNFFISAGLLW 438
+ N +LNL+S V + ++ L++
Sbjct: 408 L---ALFTDLNVLLNLVSIGTLFVFYMVANALIF 438
>At3g10600 [E] KOG1286 Amino acid transporters
Length = 584
Score = 69.7 bits (169), Expect = 1e-11
Identities = 83/389 (21%), Positives = 157/389 (40%), Gaps = 34/389 (8%)
Query: 67 IGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGG 126
IGL M+G G+F + L + ++ +A+ + AL + Y EF +P GG
Sbjct: 66 IGLGIGGMIGAGVFVTTGRASRLYAGPSI-VVSYAIAGLCALLSAFCYTEFAVHLPVAGG 124
Query: 127 EKNYLERIFPAPKFFVT-------------CMYGAYVFFLGWAAGNSVNTAVMFLTAANA 173
+Y+ F F+T + + +LG A G S + ++
Sbjct: 125 AFSYIRITFGEFPAFITGANLIMDYVLSNAAVSRGFTAYLGSAFGISTSEWRFIVSGLPN 184
Query: 174 DITEWNQRGIGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLK 233
E + + + V+ F+I + + + +L I ++F+ V G+ G +K
Sbjct: 185 GFNEIDPIAV-IVVLAVTFVI-CYSTRESSKVNMVLTALHIAFIVFVIVMGFSK--GDVK 240
Query: 234 DGYKTDNFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPT 293
+ + DN N G G+ N V S++GY V+ EVK+PV+ + +
Sbjct: 241 NLTRPDNPENP-SGFFPFGVSGVFNGAAMVYLSYIGYDAVSTMAEEVKDPVKDIPMGISG 299
Query: 294 SLIFLAIVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSA-- 351
S+ + ++Y + I+ ++P + LI + AF +VG+ A
Sbjct: 300 SVAIVIVLYCLMAISMSMLLPYD------LIDAEAPYSAAFSKSEGWEWVTRVVGIGASF 353
Query: 352 --LGNVMSVIFSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPP 409
L +++ + Q R + +GR V+P +FA P S V + T +
Sbjct: 354 GILTSLIVAMLGQARYMCVIGRSRVVPI--WFAKVHPKTSTPVNASAFLGIFTAVL---A 408
Query: 410 AGDAYNFVLNLISYPMNIVNFFISAGLLW 438
N +LNL+S V + ++ +++
Sbjct: 409 LFTDLNVLLNLVSIGTLFVFYMVANAVIF 437
>CE17868 [E] KOG1287 Amino acid transporters
Length = 662
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/200 (25%), Positives = 99/200 (49%), Gaps = 9/200 (4%)
Query: 181 RGIGVAVVGFAFLINSVNVK-VGLYIQNILGIFKIGVVLFIAVTGWVALGGGLKDGYKTD 239
R +G +++ L+N ++K V Q + K+ V I +TG + +T
Sbjct: 296 RLVGFSMLWPLMLLNFFSLKKVAGAFQIVATAIKLIVASIIIITGLYHI----IFKQQTQ 351
Query: 240 NFHNAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLA 299
NF N+F G+ + +V +Y+ ++++ G+ +N+ E++NP RTL IA + + A
Sbjct: 352 NFKNSFTGS-DWNPGNLVLGVYSGLFAYNGWDVLNFGAEEIENPRRTLPIAAISGIAISA 410
Query: 300 IVYIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXV---LVGLSALGNVM 356
V+I +N++YF+V+ E F+ S + V F + F L+ L +G++
Sbjct: 411 TVFILMNVSYFSVLSVEDFKNSPAVAVVRTFFITFAERTLGDFHYAIPFLISLLLIGSMN 470
Query: 357 SVIFSQGRIIQQLGREGVLP 376
+ IF+ R + ++ V+P
Sbjct: 471 TTIFACSRYMYSGAQQSVMP 490
Score = 57.0 bits (136), Expect = 8e-08
Identities = 29/71 (40%), Positives = 46/71 (63%)
Query: 61 LGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTA 120
+GLI+ I ++G+GIF ++I +GSVGL+L +WA+ A I+L G Y+E GT+
Sbjct: 14 IGLITAISYTVGDIVGSGIFISPTSILNHAGSVGLSLCLWALCACISLFGALSYVELGTS 73
Query: 121 IPRNGGEKNYL 131
I ++G + YL
Sbjct: 74 IRKSGCDFAYL 84
>Hs17439329 [E] KOG1286 Amino acid transporters
Length = 737
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/351 (20%), Positives = 136/351 (38%), Gaps = 59/351 (16%)
Query: 56 KGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYM 115
K ++ L + I L +GTG++ VS + G+ ++ + + A+ ++ Y
Sbjct: 14 KLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVCYA 72
Query: 116 EFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYV-FFLGW----------AAGNSVNTA 164
EFG +P+ G +VT G +V FF+GW AAG S ++
Sbjct: 73 EFGVRVPKTTGSAYTYS--------YVTV--GEFVAFFIGWNLILEYLIGTAAGASALSS 122
Query: 165 VMFLTAANADITEWNQRGIG-----------------VAVVGFAFLINSVNVKVGLYIQN 207
MF + AN I+ W +G + + +I ++ VK + N
Sbjct: 123 -MFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNN 181
Query: 208 ILGIFKIGVVLFIAVTGWVALGGGLKDGYKTDNFHNAFEGTGNATAYG---IVNALYNVI 264
+L + + V +FI + G + G + G +G ++
Sbjct: 182 VLNVLNLAVWVFIMIAGLFFING-------------KYWAEGQFLPHGWSGVLQGAATCF 228
Query: 265 WSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFAVVPKEVFRTSKLI 324
++F+G+ + E KNP ++ A SL+ Y+ V++ +VP T
Sbjct: 229 YAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTES-P 287
Query: 325 LVADFFELAFXXXXXXXXXXVLVGLSALGNVMSVIFSQGRIIQQLGREGVL 375
L+ F F + GL+ +++ +F R+I + +G+L
Sbjct: 288 LMEMFVAHGFYAAKFVVAIGSVAGLTV--SLLGSLFPMPRVIYAMAGDGLL 336
>YGR191w [E] KOG1286 Amino acid transporters
Length = 603
Score = 60.8 bits (146), Expect = 5e-09
Identities = 76/322 (23%), Positives = 127/322 (38%), Gaps = 22/322 (6%)
Query: 4 SRSFLSQLNVFNKDNYEIST-DSKTLDTDANPTGTSDDNRSVETGEHFDVELDKGSKKLG 62
S +F+++L + +S+ DS ++ N +SD R E E D+ SK L
Sbjct: 32 STTFVTELTSKTDSAFPLSSKDSPGINQTTNDITSSDRFRRNEDTEQEDINNTNLSKDLS 91
Query: 63 LISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAIP 122
+ + L +GTG++ + + G L +I W + + + E A P
Sbjct: 92 VRHLLTLAVGGAIGTGLYVNTGAALSTGGPASL-VIDWVIISTCLFTVINSLGELSAAFP 150
Query: 123 RNGGEKNYLER-IFPAPKFFVTCMYGAYVFFLGWAAGNSVNTAVMFLTAANADITEWNQR 181
GG Y R I P+ F V Y A L + L AA+ I WN +
Sbjct: 151 VVGGFNVYSMRFIEPSFAFAVNLNYLAQWLVL----------LPLELVAASITIKYWNDK 200
Query: 182 GIGVAVVGFAF----LINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWV-ALGGGLKDGY 236
A V + L N ++VK + +L + KI ++ + G V + GGG GY
Sbjct: 201 INSDAWVAIFYATIALANMLDVKSFGETEFVLSMIKILSIIGFTILGIVLSCGGGPHGGY 260
Query: 237 KTDNFHN---AFEGTGNATAY-GIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGP 292
+ + AF G + T + G+ + +S+ G + E KNP T+ A
Sbjct: 261 IGGKYWHDPGAFVGHSSGTQFKGLCSVFVTAAFSYSGIEMTAVSAAESKNPRETIPKAAK 320
Query: 293 TSLIFLAIVYIFVNIAYFAVVP 314
+ + Y+ + +VP
Sbjct: 321 RTFWLITASYVTILTLIGCLVP 342
>CE09606 [E] KOG1286 Amino acid transporters
Length = 583
Score = 58.9 bits (141), Expect = 2e-08
Identities = 75/365 (20%), Positives = 144/365 (38%), Gaps = 57/365 (15%)
Query: 42 RSVETGEHFDVELDKGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIM-W 100
++ + G H + ++ + L ++ + + M+G GI+ ++ ++ + G A+I+ +
Sbjct: 14 KTFDGGSHLESQM---KRCLTILDVMFIAIGHMIGAGIYVLTGSV--VRNQAGPAIILSF 68
Query: 101 AVGAIIALAGLYVYMEFGTAIPRNGGEKNYLERIFPAPKFFVTCMYGAYVFFLGWAA--- 157
AL + Y EFG PR G Y M + F +GW
Sbjct: 69 IFSGFAALLSAFSYAEFGARFPRAGSAYTYS----------YVGMGEIWAFIVGWTVPLE 118
Query: 158 ---GNSV---NTAVMFLTAANADITEWNQRGIGVAVVG---FA--------FLINSVNVK 200
GN+ + + F + ++ W +G G FA FL+ V V
Sbjct: 119 YMIGNAAVARSWSAYFDNLVSKSVSNWTLDTVGRLSDGKGFFALYPDFLAFFLLFLVAVA 178
Query: 201 VGL---YIQNILGIF---KIGVVLFIAVTGWVALGGGLKDGYKTDNFHNAFEGTGNATAY 254
V + + N+ F + V+ F+ + G L G D G Y
Sbjct: 179 VAMGSKFSANVNTSFVFLNLAVLAFVIICGLTYADFSLWSGTYQD-------GRSKFFPY 231
Query: 255 GIVNALYNV---IWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVYIFVNIAYFA 311
GI A+ ++F+G+ + A E KNP RT+ +A TSL ++++Y+ + +
Sbjct: 232 GIQGAISGASTCFFAFIGFEALATAGEEAKNPHRTIPLATFTSLAIISVIYVLMGASLTL 291
Query: 312 VVPKEVFRTSKLILVADFFEL-AFXXXXXXXXXXVLVGLSALGNVMSVIFSQGRIIQQLG 370
++P ++ A FE+ L G+ L N+++ F+ R + +
Sbjct: 292 MIPYDLVDPDAAFAAA--FEMKGATVAKIIMSVGALAGM--LNNLVTGSFALPRAVYAMA 347
Query: 371 REGVL 375
+G++
Sbjct: 348 DDGLI 352
>At1g17120 [E] KOG1286 Amino acid transporters
Length = 590
Score = 58.9 bits (141), Expect = 2e-08
Identities = 99/468 (21%), Positives = 177/468 (37%), Gaps = 63/468 (13%)
Query: 74 MLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGGEKNYLE- 132
++G+G+F ++ + G+ ++ +A+ + AL + Y EFG IP GG +YL
Sbjct: 98 VVGSGVFVITGQEARV-GAGPAVVLSYAISGVSALLSVLCYAEFGVEIPVAGGSFSYLRV 156
Query: 133 ------RIFPAPKFFVTCMYGAYVFFLGWA---AGNSVNTAVMFLTAANADITEWNQRG- 182
A + M GA W+ A N + F ++ ++
Sbjct: 157 ELGDFIAFIAAGNILLEAMVGAAGLGRSWSSYLASLVKNDSDYFRIKVDSFAKGFDLLDP 216
Query: 183 IGVAVVGFAFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLKDGYKTDNFH 242
+ VAV+ A I K ++ I + + +++FI V G+ KT N
Sbjct: 217 VAVAVLLVANGIAMTGTKRTSWLNLITSMVTVCIIVFIVVVGFTHS--------KTSNLV 268
Query: 243 NAFEGTGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVY 302
F A G+V + V WS+ G+ V E + P R + I S+ + +VY
Sbjct: 269 PFFP----YGAKGVVQSAAVVYWSYTGFDMVANMAEETEKPSRDIPIGLVGSMSMITVVY 324
Query: 303 IFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNVMSVI--- 359
+ +A +V + VA F ++ LVG+ AL + + +
Sbjct: 325 CLMALALTMMVKYTEIDANAAYSVA-FAQIGM------KWAKYLVGICALKGMTTSLLVG 377
Query: 360 -FSQGRIIQQLGREGVLPFSNFFATSKPFDSPCVGLFQHFIVCTVTIIAPPAG--DAYNF 416
Q R Q+ R ++P +FA P + + VTI++ +
Sbjct: 378 SLGQARYTTQIARSHMIP--PWFALVHPKTGTPI-----YATLLVTILSSIISFFTSLEV 430
Query: 417 VLNLISYPMNIVNFFISAGLLWIHWERKKGRTMWDPPIKAGIPVIAFFMLANLYLIVAPY 476
+ ++ S+ + ++ LL + K D +AG+ L L+LI+A
Sbjct: 431 LSSVFSFATLFIFMLVAVALLVRRYYVK------DVTPEAGL----LKFLGFLFLIIASS 480
Query: 477 IPPSNGESVYQSLPYWIHCVVAWGIFAVGGIYWVVWAVVLPKIGKYEL 524
I S W V W + V G+ W + + L + KY +
Sbjct: 481 IGVS---------ALWNSGVKGWIAYTVTGVIWFIGTLGLALLPKYRV 519
>At5g36940 [E] KOG1286 Amino acid transporters
Length = 632
Score = 56.6 bits (135), Expect = 1e-07
Identities = 86/374 (22%), Positives = 137/374 (35%), Gaps = 62/374 (16%)
Query: 41 NRSVETGEHFDVELDKGSKKLGLISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMW 100
N ET H + +K L I + +G G++ + T+ LAL
Sbjct: 17 NGKAETHHHHQ----QLAKALTFPHLIAIGVGSTIGAGVYILVGTVAREHSGPALALSFL 72
Query: 101 AVGAIIALAGLYVYMEFGTAIPRNGGEKNYLE------RIFPAPKFFVTCMYGAYVFFLG 154
G AL+ + Y E + P G +Y + + Y + + +G
Sbjct: 73 IAGISAALSA-FCYAELSSRFPSAGSAYHYSYICIGEGLLIAFAVLLMNSWYCSVAWLIG 131
Query: 155 WAA-------------GNSVNTAVMF--LTAANADITEWNQRGIGVAVVGFA----FLIN 195
WA G S N A++F + G+ + V A F++
Sbjct: 132 WALILEYTIGGSTVARGISPNLAMIFGGEDCLPTILARHQIPGLDIVVDPCAAVLVFIVT 191
Query: 196 SV---NVKVGLYIQNILGIFKIGVVLFIAV--------TGWVALGGGLKDGYKTDNFHNA 244
+ VK + Q I+ + V++F+ V TGWV G L GY F
Sbjct: 192 GLCCLGVKESTFAQGIVTTANVFVMIFVIVAGSYLCFKTGWV--GYELPTGY----FPYG 245
Query: 245 FEG--TGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVY 302
+G TG+AT V ++++G+ V EVKNP R L + SL+ ++Y
Sbjct: 246 VDGMLTGSAT----------VFFAYIGFDTVASMAEEVKNPRRDLPLGIGISLLLCCLLY 295
Query: 303 IFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNVMSVIFSQ 362
+ V++ +VP I A V+ SAL M I Q
Sbjct: 296 MMVSVVIVGLVPYYAMDPDTPISSAFSSHGIQWAAYLINLGAVMALCSAL---MGSILPQ 352
Query: 363 GRIIQQLGREGVLP 376
RI+ + R+G+LP
Sbjct: 353 PRILMAMARDGLLP 366
>Hs13654280 [E] KOG1287 Amino acid transporters
Length = 180
Score = 53.9 bits (128), Expect = 6e-07
Identities = 23/73 (31%), Positives = 43/73 (58%)
Query: 63 LISCIGLICNRMLGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAIP 122
L+ + +I ++G+GIF + + +GS GLAL++WA + ++ G Y E GT I
Sbjct: 52 LLKGVAVIVVAIMGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTIS 111
Query: 123 RNGGEKNYLERIF 135
++GG+ Y+ ++
Sbjct: 112 KSGGDYAYMLDVY 124
>SPBPB2B2.01 [E] KOG1286 Amino acid transporters
Length = 585
Score = 53.1 bits (126), Expect = 1e-06
Identities = 77/318 (24%), Positives = 124/318 (38%), Gaps = 34/318 (10%)
Query: 75 LGTGIFAVSSTIYTLSGSVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGGEKNYLERI 134
+GTG++ SS G+ + + VG ++ +Y E A P G + R
Sbjct: 97 IGTGVWVGSSKSLYRGGAASVLIDYCIVGTMV-FCTVYALGELAVAFPTRGSFVTHATR- 154
Query: 135 FPAPKFFVTCMYGAYVFFLGWAAGNS-VNTAVMFLTAANADITEWNQRGIGVAV---VGF 190
F+ +G F L W S + T + LT I W G+ V + F
Sbjct: 155 ------FIDESWG---FALSWNYVFSFIVTIPLELTTGTMMIKYWTNLNSGIWVTVFIVF 205
Query: 191 AFLINSVNVKVGLYIQNILGIFKIGVVLFIAVTGWVALGGGLK-DGYKTDNFHNAFEGTG 249
F IN VK ++ I+ K+ +A+ G++ LG + G TD H + GT
Sbjct: 206 LFFINIFGVKGYGEMEFIMSTIKV-----VAMCGFIILGIIIDCGGVPTD--HRGYMGTH 258
Query: 250 ----NATAY---GIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAIVY 302
NA + G + +SF G V A E +NP + +A +L +AI Y
Sbjct: 259 IFRENAFRHKFKGFCAVFTSAAFSFSGTEYVGVAAAETENPAKAFPVAVRQTLFRIAIFY 318
Query: 303 IF-VNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVL---VGLSALGNVMSV 358
I + I + + TS + A F LA +L + +S + + +
Sbjct: 319 ILSLFIVSLLISGADPRLTSYHGVDASPFVLAIKDANIKALPSILNAIILISVISSANAQ 378
Query: 359 IFSQGRIIQQLGREGVLP 376
+++ R I LG G P
Sbjct: 379 LYAGSRAIHSLGCNGFAP 396
>SPCC74.04 [E] KOG1289 Amino acid transporters
Length = 557
Score = 50.4 bits (119), Expect = 7e-06
Identities = 87/417 (20%), Positives = 162/417 (37%), Gaps = 51/417 (12%)
Query: 27 TLDTDANPTGTSDDNRSVETGEHFDV-------ELDKGSKKLGLISCIGLICNRMLGTGI 79
++ + +NPT + N + E D+ E +G + S + +LG
Sbjct: 22 SIHSTSNPTNPEEPNITSEADNAEDLAALGYKQEFQRGLSLFSVFS----VSFSLLGLLP 77
Query: 80 FAVSSTIYTL--SGSVGLALIMWAVGAIIALAGLYVYMEFGTAIPRNGGEKNYLERIFPA 137
++ Y++ +G+ GL L W + + + E +A+P +GG Y A
Sbjct: 78 SVATTLPYSIGYTGTPGL-LWGWLIAMVFIICIALSMAELCSAMPTSGGL--YYAAAVLA 134
Query: 138 PKFFVTCMYGAYVFFLGWA-------AGNSVN--TAVMFLTAANA-----DITEWNQRGI 183
P+ + +F GW+ G S+N TA M L A N ++ + +
Sbjct: 135 PEGWGPLA----AWFTGWSNYIAQLVGGPSINYSTAAMLLGAVNIGNPNYEVQNYQLFLV 190
Query: 184 GVAVVGFAFLINSVNVKVGLYIQ--NILGIFKIGVVLFIAVTGWVALGGGLKDGYKTDNF 241
+A+ F++ S+ K YI N +G + + LFI++ +A+ +T
Sbjct: 191 SIAIQFIHFILASMPTK---YIAKLNSVGTYLNTLFLFISMIVILAMSSKNHGFNETSKV 247
Query: 242 HNAFEG-TGNATAYGIVNALYNVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSLIFLAI 300
+ E T + I+ + VIW+ GY + E N + P +I A
Sbjct: 248 WSHIENYTDWPDGFAILMSFCGVIWTMSGYDAPFHMSEETANA----SVNAPRGIILTAA 303
Query: 301 V-----YIFVNIAYFAVVPKEVFRTSKLILVADFFELAFXXXXXXXXXXVLVGLSALGNV 355
+ ++ + + VV + T + A + + + S L
Sbjct: 304 IGGIMGWVMQIVIAYTVVDQTAVVTGSDSMWATYLSQCLPKRAALGILSLTIVSSFLMGQ 363
Query: 356 MSVIFSQGRIIQQLGREGVLPFSNFFATSKPF-DSPCVGLFQHFIVCTVTIIAPPAG 411
++I S RI R+GVLP+S + AT P +P +F +F++ + + AG
Sbjct: 364 SNLIASS-RIAYSYARDGVLPYSEWVATVNPITKTPIRAVFVNFVIGVLILFLAFAG 419
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.324 0.141 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,118,101
Number of Sequences: 60738
Number of extensions: 1474090
Number of successful extensions: 3350
Number of sequences better than 1.0e-05: 36
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3253
Number of HSP's gapped (non-prelim): 49
length of query: 578
length of database: 30,389,216
effective HSP length: 112
effective length of query: 466
effective length of database: 23,586,560
effective search space: 10991336960
effective search space used: 10991336960
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)