ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3398 good U KOG3230 Intracellular trafficking, secretion, and vesicular transport Vacuolar assembly/sorting protein DID4
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3398 Similar to YKL002w SP|P36108 class E
vacuolar-protein sorting and endocytosis factor singleton [INTRON]
(191 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL002w [U] KOG3230 Vacuolar assembly/sorting protein DID4 217 9e-57
CE21987 [U] KOG3230 Vacuolar assembly/sorting protein DID4 134 1e-31
At2g06530 [U] KOG3230 Vacuolar assembly/sorting protein DID4 129 2e-30
7301433 [U] KOG3230 Vacuolar assembly/sorting protein DID4 124 6e-29
Hs7656922 [U] KOG3230 Vacuolar assembly/sorting protein DID4 120 9e-28
SPAC4F8.01 [U] KOG3230 Vacuolar assembly/sorting protein DID4 111 7e-25
At1g03950 [U] KOG3230 Vacuolar assembly/sorting protein DID4 89 5e-18
At5g44560 [U] KOG3230 Vacuolar assembly/sorting protein DID4 82 4e-16
Hs7661634 [U] KOG3231 Predicted assembly/vacuolar sorting protein 67 1e-11
Hs14721561 [U] KOG3231 Predicted assembly/vacuolar sorting protein 67 1e-11
Hs9966901 [U] KOG3232 Vacuolar assembly/sorting protein DID2 55 6e-08
YKL041w [U] KOG3229 Vacuolar sorting protein VPS24 54 1e-07
7293876 [U] KOG3232 Vacuolar assembly/sorting protein DID2 52 4e-07
7295486 [U] KOG3231 Predicted assembly/vacuolar sorting protein 52 5e-07
CE27211 [U] KOG3229 Vacuolar sorting protein VPS24 49 4e-06
At1g17730 [U] KOG3232 Vacuolar assembly/sorting protein DID2 49 5e-06
CE20715 [U] KOG3232 Vacuolar assembly/sorting protein DID2 48 9e-06
Hs7706353 [U] KOG3229 Vacuolar sorting protein VPS24 45 5e-05
At1g73030 [U] KOG3232 Vacuolar assembly/sorting protein DID2 45 8e-05
At5g22950 [U] KOG3229 Vacuolar sorting protein VPS24 44 1e-04
CE07786 [U] KOG3231 Predicted assembly/vacuolar sorting protein 43 2e-04
7296875 [U] KOG3229 Vacuolar sorting protein VPS24 42 4e-04
YKR035w-a [U] KOG3232 Vacuolar assembly/sorting protein DID2 41 0.001
SPBC13G1.12 [U] KOG3232 Vacuolar assembly/sorting protein DID2 41 0.001
Hs5032291 [NTZ] KOG4286 Dystrophin-like protein 31 0.91
Hs5032289 [NTZ] KOG4286 Dystrophin-like protein 31 0.91
Hs5032287 [NTZ] KOG4286 Dystrophin-like protein 31 0.91
Hs5032285 [NTZ] KOG4286 Dystrophin-like protein 31 0.91
Hs5032283 [NTZ] KOG4286 Dystrophin-like protein 31 0.91
Hs5032281 [NTZ] KOG4286 Dystrophin-like protein 31 0.91
At2g25640 [K] KOG1634 Predicted transcription factor DATF1 conta... 31 0.91
HsM7019487 [R] KOG2220 Predicted signal transduction protein 31 1.2
Hs20535508 [R] KOG2220 Predicted signal transduction protein 31 1.2
Hs20336209 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box... 31 1.2
Hs20336207 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box... 31 1.2
Hs20336205 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box... 31 1.2
7290758 [K] KOG1657 CCAAT-binding factor subunit C (HAP5) 30 1.5
Hs4505541 [U] KOG0946 ER-Golgi vesicle-tethering protein p115 28 5.9
CE19137_1 [R] KOG3665 ZYG-1-like serine/threonine protein kinases 28 7.7
>YKL002w [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 232
Score = 217 bits (552), Expect = 9e-57
Identities = 121/191 (63%), Positives = 135/191 (70%), Gaps = 6/191 (3%)
Query: 1 MIQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVS 60
++ EIKKSAKNGQV AAK+QAKDLVRTR Y +KF NMK QLQAISLR+QAVRSSDQM S
Sbjct: 46 LVSEIKKSAKNGQVAAAKVQAKDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQMTRS 105
Query: 61 MREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
M EATGLLAGMNR+MNLPQLQRISMEFEKQSDLM QRQEFMDE+I
Sbjct: 106 MSEATGLLAGMNRTMNLPQLQRISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDEDEEAD 165
Query: 121 XIVNRVLDEIGVDLNSKLQTAPQDLVKNXXXXXXXXXXXXXXIGSSGDGPGPVTGSTTDD 180
IVN+VLDEIGVDLNS+LQ+ PQ+LV N G G DD
Sbjct: 166 EIVNKVLDEIGVDLNSQLQSTPQNLVSNAPIAETAMGI------PEPIGAGSEFHGNPDD 219
Query: 181 ELQARLNSLKR 191
+LQARLN+LK+
Sbjct: 220 DLQARLNTLKK 230
>CE21987 [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 237
Score = 134 bits (336), Expect = 1e-31
Identities = 75/195 (38%), Positives = 111/195 (56%), Gaps = 5/195 (2%)
Query: 1 MIQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVS 60
+I +IK AK Q+++ K+ AKDLVRTR+Y +KF MK +QA+SL+VQ ++S D MA +
Sbjct: 43 VIADIKNMAKKNQMDSVKVMAKDLVRTRRYIKKFIVMKANIQAVSLKVQTLKSQDAMASA 102
Query: 61 MREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
M+ T + MNR +NLPQ+Q+I MEFEKQS++M+ ++E M ++I
Sbjct: 103 MKGVTKAMQSMNRQLNLPQIQKIMMEFEKQSEIMDMKEEVMGDAI-DDALGDAGDEEETD 161
Query: 121 XIVNRVLDEIGVDLNSKLQTAPQDLVKNXXXXXXXXXXXXXXIGSSG----DGPGPVTGS 176
IVN+VLDE+G+ + ++ P G SG G G+
Sbjct: 162 QIVNQVLDELGIQMGEEMAGLPSAAGGLNAGGERIGGRQAVAAGGSGGAHHGAGGAGGGN 221
Query: 177 TTDDELQARLNSLKR 191
DD+LQARL+ L+R
Sbjct: 222 DVDDDLQARLDQLRR 236
>At2g06530 [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 218
Score = 129 bits (324), Expect = 2e-30
Identities = 74/191 (38%), Positives = 106/191 (54%), Gaps = 10/191 (5%)
Query: 1 MIQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVS 60
+I EIKK+AK GQ+ A K+ AKDL+RTR EKF +K+QLQ +SLR+Q ++S+ M +
Sbjct: 37 LINEIKKTAKQGQMGAVKVMAKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEA 96
Query: 61 MREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
M+ T + MNR MNLP LQ+I EFE+Q++ ME E M ++I
Sbjct: 97 MKGVTKAMGQMNRQMNLPSLQKIMQEFERQNEKMEMVSEVMGDAI-DDALEGDEEEEETE 155
Query: 121 XIVNRVLDEIGVDLNSKLQTAPQDLVKNXXXXXXXXXXXXXXIGSSGDGPGPVTGSTTDD 180
+V++VLDEIG+D+N +L AP V SG D
Sbjct: 156 DLVSQVLDEIGIDINQELVNAPSGAVAVPAAKNKVVQAEATGAEDSGG---------IDS 206
Query: 181 ELQARLNSLKR 191
+LQARL++L++
Sbjct: 207 DLQARLDNLRK 217
>7301433 [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 256
Score = 124 bits (312), Expect = 6e-29
Identities = 74/214 (34%), Positives = 115/214 (53%), Gaps = 24/214 (11%)
Query: 1 MIQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVS 60
+I +IKK AK GQ++A KI AKDLVRTR+Y +KF MK +QA+SL++Q ++S + MA +
Sbjct: 43 IIADIKKMAKEGQMDAVKIMAKDLVRTRRYAKKFMLMKANIQAVSLKIQTLKSQNTMAQA 102
Query: 61 MREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
M+ T + MNR +NLPQ+Q+I +FEKQS++M+ ++E ++++I
Sbjct: 103 MKGVTKAMQNMNRQLNLPQIQKILQDFEKQSEMMDMKEEMINDAI-DDAMEDEGDEEETD 161
Query: 121 XIVNRVLDEIGVDLNSKLQTAPQD----LVKNXXXXXXXXXXXXXXIGSSG--------- 167
+V++VLDE+G+ L +L P + +G G
Sbjct: 162 AVVSQVLDELGLQLGEQLGDLPSASGSLSIAGGAGAQKAQAVAAGGVGGGGAAGGGGASG 221
Query: 168 ---DGPGPVTG-------STTDDELQARLNSLKR 191
GPG G S D +LQARL+ L++
Sbjct: 222 GGAGGPGAPGGSGASSPMSDADADLQARLDKLRK 255
>Hs7656922 [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 222
Score = 120 bits (302), Expect = 9e-28
Identities = 58/142 (40%), Positives = 95/142 (66%), Gaps = 1/142 (0%)
Query: 1 MIQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVS 60
+I +IKK AK GQ++A +I AKDLVRTR+Y KF M+ +QA+SL++Q ++S++ MA +
Sbjct: 43 IIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQA 102
Query: 61 MREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
M+ T + MNR + LPQ+Q+I MEFE+Q+++M+ ++E M+++I
Sbjct: 103 MKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAI-DDAMGDEEDEEESD 161
Query: 121 XIVNRVLDEIGVDLNSKLQTAP 142
+V++VLDE+G+ L +L P
Sbjct: 162 AVVSQVLDELGLSLTDELSNLP 183
>SPAC4F8.01 [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 141
Score = 111 bits (277), Expect = 7e-25
Identities = 68/167 (40%), Positives = 94/167 (55%), Gaps = 27/167 (16%)
Query: 25 VRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNRSMNLPQLQRIS 84
+R R +K N KTQLQAISLR+Q +R+S+QM SMR AT LL GMN+SMN+P + RI+
Sbjct: 1 MRLRNSRKKMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMARIT 60
Query: 85 MEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIVNRVLDEIGVDLNSKLQTAPQD 144
+FE+++++MEQRQE +DE++ +VN+VLDEIGVDL+ L A
Sbjct: 61 QQFERENEIMEQRQEMIDENM--DDALEEDDEEEADELVNKVLDEIGVDLSQGLPDAATQ 118
Query: 145 LVKNXXXXXXXXXXXXXXIGSSGDGPGPVTGSTTDDELQARLNSLKR 191
+ G V T+D LQARL+ L +
Sbjct: 119 I-------------------------GTVPELKTEDNLQARLDELAK 140
>At1g03950 [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 213
Score = 88.6 bits (218), Expect = 5e-18
Identities = 56/190 (29%), Positives = 94/190 (49%), Gaps = 21/190 (11%)
Query: 1 MIQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVS 60
++ EIK++AK+G A KI A+ L+R R+ + Q++ I+ QA+ + +A
Sbjct: 45 LVLEIKRTAKSGNEGATKILARQLIRLRQQIANLQGSRAQMRGIATHTQAMHAHTSVAAG 104
Query: 61 MREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
M+ AT +A M+++M+ + ++ EF+KQS M+ E M +SI
Sbjct: 105 MQGATKAMAAMSKNMDPAKQAKVMREFQKQSAQMDMTTEMMSDSI-DDALDNDEAEDETE 163
Query: 121 XIVNRVLDEIGVDLNSKLQTAPQDLVKNXXXXXXXXXXXXXXIGSSGDGPGPVTGSTTDD 180
+ N+VLDEIG+D+ S+L +AP+ G G GS+ D
Sbjct: 164 DLTNQVLDEIGIDIASQLSSAPK--------------------GKIGGKKAEDVGSSGID 203
Query: 181 ELQARLNSLK 190
EL+ RL +L+
Sbjct: 204 ELEKRLAALR 213
>At5g44560 [U] KOG3230 Vacuolar assembly/sorting protein DID4
Length = 222
Score = 82.0 bits (201), Expect = 4e-16
Identities = 54/191 (28%), Positives = 89/191 (46%), Gaps = 11/191 (5%)
Query: 1 MIQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVS 60
++ EIKK+AK G A KI A+ LVR R+ + Q++ ++ QA+ +S ++
Sbjct: 42 LVAEIKKTAKTGNEAATKILARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSG 101
Query: 61 MREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
M+ AT + MN+ M + ++ +F+KQS ++ E M E+I
Sbjct: 102 MKGATKAMVAMNKQMAPTKQAKVIKDFQKQSAQLDMTIEMMSEAI-DETLDKDEAEEETE 160
Query: 121 XIVNRVLDEIGVDLNSKLQTAPQDLVKNXXXXXXXXXXXXXXIGSSGDGPGPVTGSTTDD 180
+ N+VLDEIGV + S+L +AP+ + S + D
Sbjct: 161 DLTNQVLDEIGVGVASQLSSAPKGRIATKTAAPPASTAATNKNSESSE----------VD 210
Query: 181 ELQARLNSLKR 191
EL+ RL SL+R
Sbjct: 211 ELEKRLASLRR 221
>Hs7661634 [U] KOG3231 Predicted assembly/vacuolar sorting protein
Length = 213
Score = 67.0 bits (162), Expect = 1e-11
Identities = 39/139 (28%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Query: 4 EIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMRE 63
EIKK AK G A K+ AK LV RK + + +++ ++S + + + S +MA +M
Sbjct: 45 EIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMST 104
Query: 64 ATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIV 123
+ +N+ M+ + + F+K++ ME +E +++++ IV
Sbjct: 105 TAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQD-IV 163
Query: 124 NRVLDEIGVDLNSKLQTAP 142
N+VLDEIG++++ K+ AP
Sbjct: 164 NQVLDEIGIEISGKMAKAP 182
>Hs14721561 [U] KOG3231 Predicted assembly/vacuolar sorting protein
Length = 213
Score = 67.0 bits (162), Expect = 1e-11
Identities = 39/139 (28%), Positives = 73/139 (52%), Gaps = 1/139 (0%)
Query: 4 EIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMRE 63
EIKK AK G A K+ AK LV RK + + +++ ++S + + + S +MA +M
Sbjct: 45 EIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMST 104
Query: 64 ATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIV 123
+ +N+ M+ + + F+K++ ME +E +++++ IV
Sbjct: 105 TAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQD-IV 163
Query: 124 NRVLDEIGVDLNSKLQTAP 142
N+VLDEIG++++ K+ AP
Sbjct: 164 NQVLDEIGIEISGKMAKAP 182
>Hs9966901 [U] KOG3232 Vacuolar assembly/sorting protein DID2
Length = 196
Score = 55.1 bits (131), Expect = 6e-08
Identities = 30/135 (22%), Positives = 67/135 (49%), Gaps = 1/135 (0%)
Query: 4 EIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMRE 63
+IKK+ + G + A+I A++ +R + F M ++ A++ RVQ + ++ SM
Sbjct: 32 KIKKAIQKGNMEVARIHAENAIRQKNQAVNFLRMSARVDAVAARVQTAVTMGKVTKSMAG 91
Query: 64 ATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIV 123
+ ++MNL ++ + +FE Q + ++ + + M++++ ++
Sbjct: 92 VVKSMDATLKTMNLEKISALMDKFEHQFETLDVQTQQMEDTM-SSTTTLTTPQNQVDMLL 150
Query: 124 NRVLDEIGVDLNSKL 138
+ DE G+DLN +L
Sbjct: 151 QEMADEAGLDLNMEL 165
>YKL041w [U] KOG3229 Vacuolar sorting protein VPS24
Length = 224
Score = 53.9 bits (128), Expect = 1e-07
Identities = 29/127 (22%), Positives = 61/127 (47%)
Query: 3 QEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMR 62
Q IKKSAK V ++ AK+L + K ++ + QL ++ +++ + ++ M
Sbjct: 47 QLIKKSAKKNDVRTVRLYAKELYQINKQYDRMYTSRAQLDSVRMKIDEAIRMNTLSNQMA 106
Query: 63 EATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXI 122
++ GL+ +N + LPQL+ +E EK+ E +D+++
Sbjct: 107 DSAGLMREVNSLVRLPQLRNTMIELEKELMKSGIISEMVDDTMESVGDVGEEMDEAVDEE 166
Query: 123 VNRVLDE 129
VN+++++
Sbjct: 167 VNKIVEQ 173
>7293876 [U] KOG3232 Vacuolar assembly/sorting protein DID2
Length = 198
Score = 52.4 bits (124), Expect = 4e-07
Identities = 30/138 (21%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Query: 6 KKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREAT 65
KK+ + G ++ A+I A++ +R + + M ++ A++ RVQ+ ++ ++ SM
Sbjct: 34 KKAIQKGNMDVARIHAENAIRQKNQAVNYLRMSARVDAVASRVQSALTTRKVTGSMAGVV 93
Query: 66 GLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIVNR 125
+ + MNL ++ + +FE Q + ++ + M E ++ +
Sbjct: 94 KAMDAAMKGMNLEKISSLMEKFESQFEDLDVQSSVM-EGTMSDTVTTSVPQGDVDNLLQQ 152
Query: 126 VLDEIGVDLNSKLQTAPQ 143
V DE G++LN +L + Q
Sbjct: 153 VADEAGLELNMELPSGVQ 170
>7295486 [U] KOG3231 Predicted assembly/vacuolar sorting protein
Length = 212
Score = 52.0 bits (123), Expect = 5e-07
Identities = 32/139 (23%), Positives = 68/139 (48%), Gaps = 1/139 (0%)
Query: 4 EIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMRE 63
EI+++A G +A +I AK LV RK + ++Q+I + + + ++ ++ +M
Sbjct: 47 EIRRNAAAGNNDACRILAKQLVEIRKQKSRTYAAAGKIQSIGYQNKNMGANIALSEAMGT 106
Query: 64 ATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIV 123
+ MN+ M + +F+ + ME E +++++ +V
Sbjct: 107 TAKTMGEMNKVMRPEAIGETVRQFQAANMKMEMTDEMINDTLDDMLNESGDEEESNA-VV 165
Query: 124 NRVLDEIGVDLNSKLQTAP 142
N+VLDEIG++++ K+ + P
Sbjct: 166 NKVLDEIGIEISGKMSSIP 184
>CE27211 [U] KOG3229 Vacuolar sorting protein VPS24
Length = 208
Score = 48.9 bits (115), Expect = 4e-06
Identities = 24/103 (23%), Positives = 59/103 (56%)
Query: 3 QEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMR 62
+EIK++AK G + I AK ++++RK K K Q+ ++ + +Q ++ +MA S++
Sbjct: 44 KEIKEAAKKGDKDVCLILAKSMIQSRKAISKIHVSKAQINSVIMCMQEQLATIRMAGSLQ 103
Query: 63 EATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
++T ++ M + + +P++ + E + + +E ++E++
Sbjct: 104 KSTEVMKSMQQLVKVPEIMKTMREMSAEMMKLGIIEEMIEETL 146
>At1g17730 [U] KOG3232 Vacuolar assembly/sorting protein DID2
Length = 203
Score = 48.5 bits (114), Expect = 5e-06
Identities = 31/135 (22%), Positives = 67/135 (48%), Gaps = 7/135 (5%)
Query: 4 EIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMRE 63
++KK+ + G ++ A+I A++ +R R + + ++L A+ R+ + +MA +
Sbjct: 38 KVKKAIEKGNMDGARIYAENAIRKRSEQMNYLRLSSRLDAVVARLD---TQAKMATITKS 94
Query: 64 ATGLLAGMNRSMNLPQLQRISM---EFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXX 120
T ++ + S+ LQ++S FEKQ ME + EFMD ++
Sbjct: 95 MTNIVKSLESSLTTGNLQKMSETMDSFEKQFVNMEVQAEFMDNAM-AGSTSLSTPEGEVN 153
Query: 121 XIVNRVLDEIGVDLN 135
++ +V D+ G++++
Sbjct: 154 SLMQQVADDYGLEVS 168
>CE20715 [U] KOG3232 Vacuolar assembly/sorting protein DID2
Length = 205
Score = 47.8 bits (112), Expect = 9e-06
Identities = 25/135 (18%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Query: 4 EIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMRE 63
++ + K G A++ A++ +R + + M ++ A++ RVQ + ++ SM
Sbjct: 41 KLTAAIKKGNKEVAQVHAENAIRKKNEAVNYIKMAARIDAVAARVQTAATQKRVTASMSG 100
Query: 64 ATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIV 123
+ +SMNL ++Q++ FE+ + ++ + M++++ ++
Sbjct: 101 VVKAMESAMKSMNLEKVQQLMDRFERDFEDLDVTTKTMEKTM-DGTTVLNAPKSQVDALI 159
Query: 124 NRVLDEIGVDLNSKL 138
D+ G++LN +L
Sbjct: 160 AEAADKAGIELNQEL 174
>Hs7706353 [U] KOG3229 Vacuolar sorting protein VPS24
Length = 222
Score = 45.4 bits (106), Expect = 5e-05
Identities = 24/108 (22%), Positives = 57/108 (52%), Gaps = 7/108 (6%)
Query: 3 QEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMR 62
+ +K +AK GQ + + AK+++R+RK K K + ++ + ++ + ++A S++
Sbjct: 46 RSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQ 105
Query: 63 EATGLLAGMNRSMNLPQLQRISMEFEKQ-------SDLMEQRQEFMDE 103
++T ++ M + +P++Q E K+ +++E E MD+
Sbjct: 106 KSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDD 153
>At1g73030 [U] KOG3232 Vacuolar assembly/sorting protein DID2
Length = 203
Score = 44.7 bits (104), Expect = 8e-05
Identities = 29/132 (21%), Positives = 59/132 (43%), Gaps = 1/132 (0%)
Query: 4 EIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMRE 63
++KK+ + G ++ A+I A++ +R R + + ++L A+ R+ + SM
Sbjct: 38 KVKKAIEKGNMDGARIYAENAIRKRSEQMNYLRLASRLDAVVARLDTQAKMTTITKSMTN 97
Query: 64 ATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIV 123
L + NL ++ FEKQ ME + EFM E+ ++
Sbjct: 98 IVKSLESSLATGNLQKMSETMDSFEKQFVNMEVQAEFM-ENAMAGSTSLSTPEGEVNSLM 156
Query: 124 NRVLDEIGVDLN 135
+V D+ G++++
Sbjct: 157 QQVADDYGLEVS 168
>At5g22950 [U] KOG3229 Vacuolar sorting protein VPS24
Length = 229
Score = 43.9 bits (102), Expect = 1e-04
Identities = 25/101 (24%), Positives = 52/101 (50%)
Query: 5 IKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREA 64
IK++AK + +AK AK++V +R+ + K Q+ +IS+ + + + + ++
Sbjct: 50 IKEAAKRNDMVSAKALAKEIVSSRRTVNRLYENKAQMNSISMHLGESVAIARTVGHLSKS 109
Query: 65 TGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
++ +N M PQ+ EF K+ +EF++E+I
Sbjct: 110 AEVMKLVNNLMKAPQMAATMQEFSKEMTKAGVIEEFVNEAI 150
>CE07786 [U] KOG3231 Predicted assembly/vacuolar sorting protein
Length = 290
Score = 43.1 bits (100), Expect = 2e-04
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
Query: 51 VRSSDQMAVSMREATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXX 110
++S +M +M + MN M L ++ EF+ + M +E M++++
Sbjct: 174 MQSMAKMGSAMGTTVKTMKAMNAQMPLEKVAANMREFQMAQEKMGLTEEMMNDTLDSILD 233
Query: 111 XXXXXXXXXXXIVNRVLDEIGVDLNSKLQTAP 142
IVN+VLDEIG+++NSKL P
Sbjct: 234 APGDADEQDA-IVNQVLDEIGIEMNSKLANVP 264
>7296875 [U] KOG3229 Vacuolar sorting protein VPS24
Length = 223
Score = 42.4 bits (98), Expect = 4e-04
Identities = 24/103 (23%), Positives = 54/103 (52%)
Query: 3 QEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMR 62
+ +K++A+ + I AK++V RK + K L +I ++++ S+ ++A S++
Sbjct: 46 RSLKQAAQKNDRDTCVILAKEIVNARKAINRIYTSKAHLNSIQMQMKNQLSTLRVAGSLQ 105
Query: 63 EATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
++T +L M + P+L I + K+ +E +DE++
Sbjct: 106 KSTEVLQAMQSLVRYPELAGIMRDMSKEMMKAGIIEEMLDETM 148
>YKR035w-a [U] KOG3232 Vacuolar assembly/sorting protein DID2
Length = 204
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/146 (25%), Positives = 71/146 (48%), Gaps = 17/146 (11%)
Query: 7 KSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATG 66
K A N + ++I A + +R + N + QL ++ RV +V S Q AV+MR+ +
Sbjct: 42 KRALNENEDISRIYASNAIRKK-------NERLQLLKLASRVDSVASRVQTAVTMRQVSA 94
Query: 67 LLA----GMNRS---MNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXX 119
+ GM+++ MNL Q+ I +FE+Q + ++ + E +
Sbjct: 95 SMGQVCKGMDKALQNMNLQQITMIMDKFEQQFEDLDTSVN-VYEDMGVNSDAMLVDNDKV 153
Query: 120 XXIVNRVLDEIGVDL--NSKLQTAPQ 143
++++V DE G++L ++KL P+
Sbjct: 154 DELMSKVADENGMELKQSAKLDNVPE 179
>SPBC13G1.12 [U] KOG3232 Vacuolar assembly/sorting protein DID2
Length = 178
Score = 40.8 bits (94), Expect = 0.001
Identities = 30/134 (22%), Positives = 63/134 (46%), Gaps = 15/134 (11%)
Query: 12 GQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGM 71
G A+I A + +R ++ + + +++ A+S R+Q AV+MR +G +AG+
Sbjct: 21 GNSEIARIYASNAIRKQQESLNLLKLSSRIDAVSSRLQT-------AVTMRAVSGNMAGV 73
Query: 72 NR-------SMNLPQLQRISMEFEKQSDLMEQRQEFMDESIXXXXXXXXXXXXXXXXIVN 124
R +MNL + ++ +FE Q D + + +M++++ ++
Sbjct: 74 VRGMDRAMKTMNLEMISQVMDKFEAQFDDVNVQTGYMNKAM-GSVTAVDTPQEDVDLLMQ 132
Query: 125 RVLDEIGVDLNSKL 138
V DE G++ N +
Sbjct: 133 TVADEAGLEFNQNM 146
>Hs5032291 [NTZ] KOG4286 Dystrophin-like protein
Length = 2341
Score = 31.2 bits (69), Expect = 0.91
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
+NA + AKD K E N+K LQ S R+ + S + +++ AT + R
Sbjct: 674 LNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRIDIIHS--KKTAALQSAT----PVER 727
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
L ++ ++EK + + + RQ D S+
Sbjct: 728 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSV 759
>Hs5032289 [NTZ] KOG4286 Dystrophin-like protein
Length = 2344
Score = 31.2 bits (69), Expect = 0.91
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
+NA + AKD K E N+K LQ S R+ + S + +++ AT + R
Sbjct: 677 LNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRIDIIHS--KKTAALQSAT----PVER 730
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
L ++ ++EK + + + RQ D S+
Sbjct: 731 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSV 762
>Hs5032287 [NTZ] KOG4286 Dystrophin-like protein
Length = 3681
Score = 31.2 bits (69), Expect = 0.91
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
+NA + AKD K E N+K LQ S R+ + S + +++ AT + R
Sbjct: 2014 LNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRIDIIHS--KKTAALQSAT----PVER 2067
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
L ++ ++EK + + + RQ D S+
Sbjct: 2068 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSV 2099
>Hs5032285 [NTZ] KOG4286 Dystrophin-like protein
Length = 3562
Score = 31.2 bits (69), Expect = 0.91
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
+NA + AKD K E N+K LQ S R+ + S + +++ AT + R
Sbjct: 1895 LNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRIDIIHS--KKTAALQSAT----PVER 1948
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
L ++ ++EK + + + RQ D S+
Sbjct: 1949 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSV 1980
>Hs5032283 [NTZ] KOG4286 Dystrophin-like protein
Length = 3685
Score = 31.2 bits (69), Expect = 0.91
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
+NA + AKD K E N+K LQ S R+ + S + +++ AT + R
Sbjct: 2018 LNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRIDIIHS--KKTAALQSAT----PVER 2071
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
L ++ ++EK + + + RQ D S+
Sbjct: 2072 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSV 2103
>Hs5032281 [NTZ] KOG4286 Dystrophin-like protein
Length = 3677
Score = 31.2 bits (69), Expect = 0.91
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
+NA + AKD K E N+K LQ S R+ + S + +++ AT + R
Sbjct: 2010 LNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRIDIIHS--KKTAALQSAT----PVER 2063
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
L ++ ++EK + + + RQ D S+
Sbjct: 2064 VKLQEALSQLDFQWEKVNKMYKDRQGRFDRSV 2095
>At2g25640 [K] KOG1634 Predicted transcription factor DATF1 contains PHD and
TFS2M domains
Length = 643
Score = 31.2 bits (69), Expect = 0.91
Identities = 13/27 (48%), Positives = 17/27 (62%)
Query: 163 IGSSGDGPGPVTGSTTDDELQARLNSL 189
+ SS + GP+ G T DDE+QA SL
Sbjct: 415 LNSSNESTGPINGVTIDDEMQAATGSL 441
>HsM7019487 [R] KOG2220 Predicted signal transduction protein
Length = 868
Score = 30.8 bits (68), Expect = 1.2
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 2 IQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSD---QMA 58
+ ++K G+ K ++ ++K+T+ F M SL R +D +
Sbjct: 323 VPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVPVSVQQSLAAYNQRKADLVNRSI 382
Query: 59 VSMREATGLLAGMNRSMNLP-QLQRISMEFEKQSDLMEQR 97
MREAT L G+ S+NLP ++ +S + QS L + R
Sbjct: 383 AQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSR 422
>Hs20535508 [R] KOG2220 Predicted signal transduction protein
Length = 868
Score = 30.8 bits (68), Expect = 1.2
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 2 IQEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSD---QMA 58
+ ++K G+ K ++ ++K+T+ F M SL R +D +
Sbjct: 323 VPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVPVSVQQSLAAYNQRKADLVNRSI 382
Query: 59 VSMREATGLLAGMNRSMNLP-QLQRISMEFEKQSDLMEQR 97
MREAT L G+ S+NLP ++ +S + QS L + R
Sbjct: 383 AQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSR 422
>Hs20336209 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box superfamily
Length = 2492
Score = 30.8 bits (68), Expect = 1.2
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
V A +IQ + + + + E + Q+QA++L QA S ++ V REA +
Sbjct: 2342 VTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA---SQELDVKRREAIYNDVLTKQ 2398
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFM 101
M + +QRI M Q +Q+Q+ M
Sbjct: 2399 QMLISCVQRILMNRRLQQQYNQQQQQQM 2426
>Hs20336207 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box superfamily
Length = 2288
Score = 30.8 bits (68), Expect = 1.2
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
V A +IQ + + + + E + Q+QA++L QA S ++ V REA +
Sbjct: 2138 VTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA---SQELDVKRREAIYNDVLTKQ 2194
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFM 101
M + +QRI M Q +Q+Q+ M
Sbjct: 2195 QMLISCVQRILMNRRLQQQYNQQQQQQM 2222
>Hs20336205 [K] KOG1015 Transcription regulator XNP/ATRX DEAD-box superfamily
Length = 2454
Score = 30.8 bits (68), Expect = 1.2
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 14 VNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMREATGLLAGMNR 73
V A +IQ + + + + E + Q+QA++L QA S ++ V REA +
Sbjct: 2304 VTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA---SQELDVKRREAIYNDVLTKQ 2360
Query: 74 SMNLPQLQRISMEFEKQSDLMEQRQEFM 101
M + +QRI M Q +Q+Q+ M
Sbjct: 2361 QMLISCVQRILMNRRLQQQYNQQQQQQM 2388
>7290758 [K] KOG1657 CCAAT-binding factor subunit C (HAP5)
Length = 601
Score = 30.4 bits (67), Expect = 1.5
Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 4/103 (3%)
Query: 3 QEIKKSAKNGQVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAVSMR 62
Q I + NGQ+ A ++ T N+ Q Q Q ++ Q+
Sbjct: 409 QLILTAGPNGQLTATPAPQ---TTAQQQTALLQNLAQQQQQHQQHQQQIQLLQQVVTPTG 465
Query: 63 EATGLLAGMNRSMNLPQLQRISMEFEKQSDLMEQRQEFMDESI 105
E T + +N S +L LQR+ M+ ++Q +Q+Q+ + +
Sbjct: 466 ELTNVPIAINAS-HLNLLQRLQMQQQQQQQQQQQQQQQQQQQV 507
>Hs4505541 [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 962
Score = 28.5 bits (62), Expect = 5.9
Identities = 15/66 (22%), Positives = 36/66 (53%), Gaps = 2/66 (3%)
Query: 1 MIQEIKKSAKNG--QVNAAKIQAKDLVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMA 58
MI+ +K S +G + ++A + A+D + + ++ +K+QL + S+ + +++ Q
Sbjct: 759 MIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQEL 818
Query: 59 VSMREA 64
+ EA
Sbjct: 819 LQKTEA 824
>CE19137_1 [R] KOG3665 ZYG-1-like serine/threonine protein kinases
Length = 408
Score = 28.1 bits (61), Expect = 7.7
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 13/84 (15%)
Query: 24 LVRTRKYTEKFGNMKTQLQAISLRVQAVRSSDQMAV----------SMREATGL--LAGM 71
L+ R + K NM L++ + + + D + +RE TGL ++G+
Sbjct: 59 LILRRDWINKLNNMLPSLRSFDMSNSQLDAKDFFRLCKNFPNLEFLDIRE-TGLSTISGL 117
Query: 72 NRSMNLPQLQRISMEFEKQSDLME 95
NR NL L+ +MEF D+++
Sbjct: 118 NRLQNLQILKMQNMEFHNHFDIID 141
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.128 0.327
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,871,318
Number of Sequences: 60738
Number of extensions: 225191
Number of successful extensions: 581
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 541
Number of HSP's gapped (non-prelim): 39
length of query: 191
length of database: 30,389,216
effective HSP length: 100
effective length of query: 91
effective length of database: 24,315,416
effective search space: 2212702856
effective search space used: 2212702856
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)