ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3430 good Z KOG0836 Cytoskeleton F-actin capping protein, alpha subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3430 1178443 1177658 -262
(262 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL007w [Z] KOG0836 F-actin capping protein alpha subunit 229 3e-60
Hs5453599 [Z] KOG0836 F-actin capping protein alpha subunit 119 3e-27
Hs5453597 [Z] KOG0836 F-actin capping protein alpha subunit 115 8e-26
SPAC12B10.07 [Z] KOG0836 F-actin capping protein alpha subunit 114 2e-25
CE04295 [Z] KOG0836 F-actin capping protein alpha subunit 106 4e-23
7291228 [Z] KOG0836 F-actin capping protein alpha subunit 106 4e-23
Hs15277417 [Z] KOG0836 F-actin capping protein alpha subunit 84 2e-16
At3g05520 [Z] KOG0836 F-actin capping protein alpha subunit 80 2e-15
Hs17459523 [Z] KOG0836 F-actin capping protein alpha subunit 58 2e-08
Hs22057708 [Z] KOG0836 F-actin capping protein alpha subunit 55 1e-07
>YKL007w [Z] KOG0836 F-actin capping protein alpha subunit
Length = 268
Score = 229 bits (584), Expect = 3e-60
Identities = 110/264 (41%), Positives = 168/264 (62%), Gaps = 4/264 (1%)
Query: 2 SEFEKIVRDIVFDSPPEEISLVYDNLQVLSDGQSKQQIASIIQEFNEKHRVPAAKGEERY 61
S+FE+++ I+ DSPP E+ VYD+L ++ SK I I+ +N ++ +P
Sbjct: 4 SKFEEVINKIINDSPPGELREVYDDLIKITSENSKNTILDAIENYNVQNCIPIEVNGNSV 63
Query: 62 LVSEYNKSGSKYFDPVNKVLFAVDHITREASDIEEYTSEDATQVQS---DLYDELSKYVS 118
++S+YNK G+K+FDPVN V+F+V+H+ R+ DIE Y A + +L+D+L +Y+
Sbjct: 64 IISKYNKEGAKFFDPVNSVIFSVNHLERKGLDIEPYEFTHAKIEKGQLKELHDKLHEYLL 123
Query: 119 NFFPDTAVFNVFKIPES-DQYAIIVVSNKKSLGDFWTGYWLSEYVYDVDGDTISGEVSVD 177
FP F V+ +PE + +II+VS K + +FW G+W S Y+YD++ +SG++S
Sbjct: 124 QSFPGDVSFAVYPVPEEISKISIIIVSTKYNPNNFWNGHWRSSYIYDLETRELSGQISTQ 183
Query: 178 AHYFEDGNVRFKSTASLESAQTDSPIVSIKQFENEFEKNLINKFQYMNETQFKGLRRRLP 237
HY+EDGNV F+S + + D + +I+ E FE +L F +NE QFK LRRRLP
Sbjct: 184 VHYYEDGNVSFQSGKDINQSNVDDVVCTIRDIETNFENDLDLSFFDLNEKQFKALRRRLP 243
Query: 238 VTRAKINWGQGIGNYRLGRDAAQG 261
VTR+KINWG IG+YRLG++AA+G
Sbjct: 244 VTRSKINWGSAIGSYRLGKNAAEG 267
>Hs5453599 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 286
Score = 119 bits (299), Expect = 3e-27
Identities = 79/270 (29%), Positives = 147/270 (54%), Gaps = 20/270 (7%)
Query: 6 KIVRDIVFDSPPEEISLVYDNLQVL--SDGQSKQQIASIIQEFNEKHRVPAA-KG-EERY 61
+I + +PP E + V++++++L +D ++ A ++N P +G E++
Sbjct: 15 RIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQV 74
Query: 62 LVSEYNKSGS-KYFDPVNKVLFAVDHITREASDIEEYTSEDATQV-QSDLYDELSKYVSN 119
L++E+ G+ K+ DP N++ F DH+ +EA+D E+A + ++ + L YV
Sbjct: 75 LITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKE 134
Query: 120 FFPDTAVFNVFKIPESDQYAII--VVSNKKSLGDFWTGYWLSEYVYDVDGDT--ISGEVS 175
+P+ V V+ Q II + S++ +FW G W SE+ + + T + G +
Sbjct: 135 HYPN-GVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILK 193
Query: 176 VDAHYFEDGNVRFKSTASLESAQTDS-PIVSIKQF-------ENEFEKNLINKFQYMNET 227
+ HY+EDGNV+ S ++ + T S + + K+F ENE++ + +Q M++T
Sbjct: 194 IQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDT 253
Query: 228 QFKGLRRRLPVTRAKINWGQGIGNYRLGRD 257
FK LRR+LPVTR KI+W + I +Y++G++
Sbjct: 254 TFKALRRQLPVTRTKIDWNK-ILSYKIGKE 282
>Hs5453597 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 286
Score = 115 bits (287), Expect = 8e-26
Identities = 78/269 (28%), Positives = 141/269 (51%), Gaps = 18/269 (6%)
Query: 6 KIVRDIVFDSPPEEISLVYDNLQVL--SDGQSKQQIASIIQEFNEKHRVPAA-KG-EERY 61
+I + +PP E + V++++++L +D ++ A ++N P +G E++
Sbjct: 15 RIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQV 74
Query: 62 LVSEYNKSG-SKYFDPVNKVLFAVDHITREASDIEEYTSEDATQVQSDLYDE-LSKYVSN 119
L++E+ G S++ DP NK+ F DH+ +EASD + ++ + + D L YV +
Sbjct: 75 LITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSWRESCDSALRAYVKD 134
Query: 120 FFPDTAVFNVFKIPESDQYAIIVV-SNKKSLGDFWTGYWLSEYVYDVDGDT--ISGEVSV 176
+ + K + Q I + S++ +FW G W SE+ + + T + G + +
Sbjct: 135 HYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKI 194
Query: 177 DAHYFEDGNVRFKS--------TASLESAQTDSPIVSIKQFENEFEKNLINKFQYMNETQ 228
HY+EDGNV+ S T S E+ I I+ ENE++ + +Q M++T
Sbjct: 195 QVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQTAISENYQTMSDTT 254
Query: 229 FKGLRRRLPVTRAKINWGQGIGNYRLGRD 257
FK LRR+LPVTR KI+W + I +Y++G++
Sbjct: 255 FKALRRQLPVTRTKIDWNK-ILSYKIGKE 282
>SPAC12B10.07 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 256
Score = 114 bits (284), Expect = 2e-25
Identities = 66/248 (26%), Positives = 136/248 (54%), Gaps = 12/248 (4%)
Query: 5 EKIVRDIVFDSPPEEISLVYDNLQV--LSDGQS-KQQIASIIQEFNEKHRVPAAKGEERY 61
++ + ++ +SPP E++ V +++ LSD ++ +Q+ +++N + +E+
Sbjct: 3 KEAIYKLIRESPPGEVNQVVHDIRDIGLSDEEAIHEQLKLYHEDYNSSVSI---SDDEKV 59
Query: 62 LVSEYNK-SGSKYFDPVNKVLFAVDHITREASDIEEYTSEDATQVQSDLYDELSKYVSNF 120
++S N+ G++Y+D V + F +++ T EA ++E+YT +A ++ ++ ++ K S+
Sbjct: 60 IISADNRLEGNRYYDQVLQKSFTINYETMEAENVEDYT--EAIKIPDEIVKQIKKVASDH 117
Query: 121 FPDTAVFNVFK-IPESDQYAIIVVSNKKSLGDFWTGYWLSEYVYDVDGDTISGEVSVDAH 179
+ F + K E + + I++VS+K + ++W G W Y+V + G + H
Sbjct: 118 YLSDVTFGIIKKSDEVESFTIVLVSSKYNPKNYWNGSWRCICNYNVSEKKLEGRSHIRVH 177
Query: 180 YFEDGNVRFKSTASLESA--QTDSPIVSIKQFENEFEKNLINKFQYMNETQFKGLRRRLP 237
Y+EDGNV ++ + + +T + Q EN +++ + +N+ +FK LRR+LP
Sbjct: 178 YYEDGNVWLDASRPISATVEETSKLYEVLAQVENGIQQSFNVELSSLNDKKFKELRRQLP 237
Query: 238 VTRAKINW 245
VTR KINW
Sbjct: 238 VTRQKINW 245
>CE04295 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 282
Score = 106 bits (264), Expect = 4e-23
Identities = 76/277 (27%), Positives = 145/277 (51%), Gaps = 24/277 (8%)
Query: 2 SEFEKIVRDIVFDSPPEEISLVYDNLQVL--SDGQSKQQIASIIQEFNEKHRVPAAKG-- 57
+E +I D + +PP E + V++++++L +D K + + I ++N VP
Sbjct: 7 AEKVRIASDFIKHAPPGEFNEVFNSVRMLLENDDLLKNKCVNAIAQYNVGQFVPVKLDGV 66
Query: 58 EERYLVSEYNKSGS-KYFDPVNKVLFAVDHITREASDIEEYTSEDAT--QVQSDLYDELS 114
++ L++ YN G+ +++D V+K F DH+ +EA+D++ + +E Q + L +L
Sbjct: 67 AKQTLITPYNDLGNGRFYDEVSKKSFKYDHVRKEAADLQPHPAESGITEQWRQALQTQLD 126
Query: 115 KYVSNFFPDTAVFNVFKIPESDQYAIIVVSNKKSLGDFWTGYWLSEYVYDV-DGDT---- 169
Y+ + + + VF + + I + S++ +F G W SE+ V DG +
Sbjct: 127 IYIDDHYAKSGTGVVFA--RNGVFTICIESHQFQPKNFCNGRWRSEWNVPVGDGKSGSQE 184
Query: 170 ISGEVSVDAHYFEDGNVRF--------KSTASLESAQTDSPIV-SIKQFENEFEKNLINK 220
+ G++ HY+EDGNV+ K S + +T I+ +I + E ++ +
Sbjct: 185 MKGKILSQVHYYEDGNVQLFSEKEPVLKVNVSADFDKTAKEIIHAISEEETIYQNAVQEN 244
Query: 221 FQYMNETQFKGLRRRLPVTRAKINWGQGIGNYRLGRD 257
+ M++T FK LRR+LPVTRAK++W + YR+G++
Sbjct: 245 YANMSDTTFKALRRQLPVTRAKMDWNKA-QTYRIGQE 280
>7291228 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 286
Score = 106 bits (264), Expect = 4e-23
Identities = 74/276 (26%), Positives = 139/276 (49%), Gaps = 22/276 (7%)
Query: 2 SEFEKIVRDIVFDSPPEEISLVYDNLQVL--SDGQSKQQIASIIQEFNEKHRVPAA--KG 57
+E +IV D + +PP E + V+++++ L +D K + ++N+ P
Sbjct: 9 AEKVRIVSDFILHAPPGEFNEVFNDVRELLKNDTLLKDGASHAFAQYNKDQLTPVRIEGT 68
Query: 58 EERYLVSEYNKSGS-KYFDPVNKVLFAVDHITREASDIEEYTSEDATQVQSDLYD-ELSK 115
+ ++SE+N G+ +++DP K F DH+ +EASD ++ ++ + D E
Sbjct: 69 DHNAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQDVEADATAEPWRAALDLETLA 128
Query: 116 YVSNFFPDTAVFNVFKIPESDQYA--IIVVSNKKSLGDFWTGYWLSEY--VYDVDGDT-- 169
Y ++ + V +VF + +Q I + ++ ++W G W S++ + T
Sbjct: 129 YTASHYRH-GVSSVFGKAQGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFQAGSGTAE 187
Query: 170 ISGEVSVDAHYFEDGNVRFKST--------ASLESAQTDSPIVSIKQFENEFEKNLINKF 221
+ G + V HY+EDGNV+ S+ S E I I+ ENE++ + +
Sbjct: 188 LKGVLKVQVHYYEDGNVQLVSSKECRESVVVSNEQQVAKEVIRLIEDAENEYQLAISENY 247
Query: 222 QYMNETQFKGLRRRLPVTRAKINWGQGIGNYRLGRD 257
Q M++T FK +RR+LP+TR KI+W + I +Y +G++
Sbjct: 248 QTMSDTTFKAMRRQLPITRTKIDWSK-IVSYSIGKE 282
>Hs15277417 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 299
Score = 84.3 bits (207), Expect = 2e-16
Identities = 67/267 (25%), Positives = 128/267 (47%), Gaps = 17/267 (6%)
Query: 5 EKIVRDIVFDSPPEEISLVYDNLQVLSDGQS--KQQIASIIQEFNEKHRVPAAKGEERYL 62
E+++R ++ +PP E +D+L +L + Q + +K+ VP L
Sbjct: 12 ERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDGNPVL 71
Query: 63 VSEYNKSGS-KYFDPVNKVLFAVDHITREASDIEEY--TSEDATQVQSDLYDELSKYVSN 119
+S +N G ++FD +K+ F D + + DI+ + +A ++ L L YV++
Sbjct: 72 LSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLCALKLYVND 131
Query: 120 FFPDTAVFNVFKIPESDQYAIIVVSNKK-SLGDFWTGYWLSEYVYDVDG--DTISGEVSV 176
+P + K +S +Y I + + G+ W G W S++++ V+ ++G + V
Sbjct: 132 HYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFV 191
Query: 177 DAHYFEDGNVRFKSTA----SLESAQTDSPIVS----IKQFENEFEKNLINKFQYM-NET 227
AH+F N+ + + SLE +S +++ EN+F+ ++ + Q + NE
Sbjct: 192 QAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEA 251
Query: 228 QFKGLRRRLPVTRAKINWGQGIGNYRL 254
K LRR LPVTR I+W + + + L
Sbjct: 252 LRKILRRDLPVTRTLIDWHRILSDLNL 278
>At3g05520 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 308
Score = 80.5 bits (197), Expect = 2e-15
Identities = 69/272 (25%), Positives = 130/272 (47%), Gaps = 33/272 (12%)
Query: 5 EKIVRDIVFDSPPEEISLVYDNLQ-VLSDGQSKQQIA-SIIQEFNEKHRV----PAAKGE 58
++I + ++P EI+ V +L+ VLSD + + A +N+ H + P+ G+
Sbjct: 19 KEIAKWFFLNAPAGEINYVAKDLKAVLSDEEVYNEAAMEAFPVYNKTHMICLEMPSGAGD 78
Query: 59 ERYLVSEYNK-SGSKYFDPVNKVLFAVDHITREASDIEEYTSEDATQVQSDLYD-----E 112
+VS Y++ + ++Y DP + VDH+ + + + E+ + + Y E
Sbjct: 79 --VIVSSYSEINENEYLDPRTAQVAIVDHVKQICTKVRPANDEELPSLYIEEYRYALDAE 136
Query: 113 LSKYVSNFFPD-TAVFNVFKIPESD------QYAIIVVSNKKSLGDFWTGYWLSEYVYDV 165
+ +YVS +P + N K +++ + +I+ + + S +F G W S + D
Sbjct: 137 IQRYVSESYPKGMSAVNCVKGKDNEGPGSDFELVVIITAMRLSPQNFCNGSWRSVWNIDF 196
Query: 166 DGDT----ISGEVSVDAHYFEDGNVR------FKSTASLESAQTDSPIVS--IKQFENEF 213
++ I G++ V AHYFE+GNV F+ + +SA + ++ I+ E E+
Sbjct: 197 QDESQVLDIKGKLQVGAHYFEEGNVELDAKKDFQDSTIFQSADDCAIAIANIIRHHETEY 256
Query: 214 EKNLINKFQYMNETQFKGLRRRLPVTRAKINW 245
+L + + + FK LRR+LPVTR W
Sbjct: 257 LASLEVAYSKLPDNTFKDLRRKLPVTRTLFPW 288
>Hs17459523 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 141
Score = 57.8 bits (138), Expect = 2e-08
Identities = 35/102 (34%), Positives = 61/102 (59%), Gaps = 11/102 (10%)
Query: 164 DVDGDTISGEVSVDAHYFEDGNVRFKSTASLESAQTDS-PIVSIKQF-------ENEFEK 215
+VDG ++G + + HY+E GNV+ S ++ + T S + + K+F EN+ +
Sbjct: 39 EVDGAQVAGVLKI--HYYEYGNVQSVSHKDVQDSLTVSNEVQTAKEFIKIIGNAENDHQT 96
Query: 216 NLINKFQYMNETQFKGLRRRLPVTRAKINWGQGIGNYRLGRD 257
+Q M++T F+ LRR+LPVTR KI+W + I Y++G++
Sbjct: 97 ATSENYQTMSDTTFQALRRQLPVTRRKIDWNK-ILIYQIGKE 137
>Hs22057708 [Z] KOG0836 F-actin capping protein alpha subunit
Length = 161
Score = 55.1 bits (131), Expect = 1e-07
Identities = 30/87 (34%), Positives = 50/87 (56%), Gaps = 9/87 (10%)
Query: 179 HYFEDGNVRFKSTASLESAQTDSPIVS--------IKQFENEFEKNLINKFQYMNETQFK 230
HY+ED NV+ S ++ + T S V +K ENE++ + +Q M++T FK
Sbjct: 72 HYYEDSNVQLVSHKDIQDSLTVSNEVQTAKESTKIVKAAENEYQTAISENYQTMSDTTFK 131
Query: 231 GLRRRLPVTRAKINWGQGIGNYRLGRD 257
L R+L +TR KI+W + I +Y +G++
Sbjct: 132 ALHRQLLLTRTKIDWNK-ILSYEVGKE 157
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,215,504
Number of Sequences: 60738
Number of extensions: 627907
Number of successful extensions: 1577
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1555
Number of HSP's gapped (non-prelim): 11
length of query: 262
length of database: 30,389,216
effective HSP length: 104
effective length of query: 158
effective length of database: 24,072,464
effective search space: 3803449312
effective search space used: 3803449312
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)