ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3438 good U KOG1607 Intracellular trafficking, secretion, and vesicular transport Protein transporter of the TRAM (translocating chain-associating membrane) superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3438 1181036 1182259 408
(408 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL008c [U] KOG1607 Protein transporter of the TRAM (translocati... 499 e-141
YHL003c [U] KOG1607 Protein transporter of the TRAM (translocati... 495 e-140
SPBC3E7.15c [U] KOG1607 Protein transporter of the TRAM (translo... 266 4e-71
SPAC1A6.09c [U] KOG1607 Protein transporter of the TRAM (translo... 159 7e-39
At1g13580 [U] KOG1607 Protein transporter of the TRAM (transloca... 83 6e-16
At3g19260 [U] KOG1607 Protein transporter of the TRAM (transloca... 79 1e-14
At3g25540 [U] KOG1607 Protein transporter of the TRAM (transloca... 77 4e-14
CE27675 [U] KOG1607 Protein transporter of the TRAM (translocati... 70 7e-12
ECU08g1350 [U] KOG1607 Protein transporter of the TRAM (transloc... 68 2e-11
Hs13375717 [U] KOG1607 Protein transporter of the TRAM (transloc... 64 4e-10
Hs11641421 [U] KOG1607 Protein transporter of the TRAM (transloc... 63 7e-10
7290103 [U] KOG1608 Protein transporter of the TRAM (translocati... 61 3e-09
Hs20550645 [U] KOG1607 Protein transporter of the TRAM (transloc... 56 8e-08
CE20184 [U] KOG1607 Protein transporter of the TRAM (translocati... 56 1e-07
Hs17444463 [U] KOG1608 Protein transporter of the TRAM (transloc... 54 3e-07
Hs6912450 [U] KOG1608 Protein transporter of the TRAM (transloca... 54 4e-07
Hs9937998 [U] KOG1607 Protein transporter of the TRAM (transloca... 53 7e-07
Hs7657655 [U] KOG1608 Protein transporter of the TRAM (transloca... 53 7e-07
CE18518 [U] KOG1608 Protein transporter of the TRAM (translocati... 53 7e-07
Hs20481895 [U] KOG1607 Protein transporter of the TRAM (transloc... 52 2e-06
CE18517 [U] KOG1608 Protein transporter of the TRAM (translocati... 51 3e-06
Hs20532972 [U] KOG1607 Protein transporter of the TRAM (transloc... 50 6e-06
>YKL008c [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 418
Score = 499 bits (1286), Expect = e-141
Identities = 234/384 (60%), Positives = 294/384 (75%), Gaps = 3/384 (0%)
Query: 3 PKNQSPELRRR--RTTSIGRINLGDTSVPSLSTMSVTEESKHASEARLKLLSSSSEKDID 60
P N + ++R R R +SIG+I+LGDT VPSL TM T+ESK A++ R++ LS +++ D D
Sbjct: 8 PSNNNLKVRSRPRRKSSIGKIDLGDT-VPSLGTMFETKESKTAAKRRMQRLSEATKNDSD 66
Query: 61 VLRKLWLSYRELSYRHSWLTSLLIISVIYLFYICSGNRTASNPLHMFVAISYQIGDTNMY 120
+++K+W S+RE+SYRH+W+ L+I+ +Y Y SGN T +N LH FVA+SYQIGDTN Y
Sbjct: 67 LVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAY 126
Query: 121 GKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFYYSIS 180
GKG DLCFVF+YMIFFTFLREF+M V++RP +I++ T +++I+R+MEQMY+IFY +S
Sbjct: 127 GKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVS 186
Query: 181 GPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPR 240
GPFG+Y MYH+DLW F T MY+TYPDF N +L+K+FYLGQAAFW QQ+C+L LQLEKPR
Sbjct: 187 GPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPR 246
Query: 241 KDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLDSSLTPPF 300
KD EL FHHIVTL LIW SYVFHFTKMGL +Y+TMDVSDF LS SKT NYLDS L
Sbjct: 247 KDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFS 306
Query: 301 FLFFIVSWVYLRHYINLKILWSLLTEFTTVGNYTLNFATQQYKCWISQPIIXXXXXXXXX 360
F F+V+W+YLRHYINLKILWS+LT+F T GNY LNFATQQYKCWIS PI+
Sbjct: 307 FAIFVVAWIYLRHYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQL 366
Query: 361 XXXXXXXXIARILYRLVVHGIQKD 384
I R+LYR++ GI KD
Sbjct: 367 VNLYWLFLIFRVLYRILWRGILKD 390
>YHL003c [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 411
Score = 495 bits (1275), Expect = e-140
Identities = 233/373 (62%), Positives = 286/373 (76%), Gaps = 1/373 (0%)
Query: 12 RRRTTSIGRINLGDTSVPSLSTMSVTEESKHASEARLKLLSSSSEKDIDVLRKLWLSYRE 71
RRR +S+G+I+LGDT VP + M + SK+ ++ R+K L+ S+KD D+L K+W SYRE
Sbjct: 19 RRRNSSVGKIDLGDT-VPGFAAMPESAASKNEAKKRMKALTGDSKKDSDLLWKVWFSYRE 77
Query: 72 LSYRHSWLTSLLIISVIYLFYICSGNRTASNPLHMFVAISYQIGDTNMYGKGPKDLCFVF 131
++YRHSWLT I+ +Y Y SGNRT SNPLHMFVAISYQ+ T+ Y KG KDL FVF
Sbjct: 78 MNYRHSWLTPFFILVCVYSAYFLSGNRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVF 137
Query: 132 FYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFYYSISGPFGLYIMYHT 191
FYMIFFTFLREF+M V++RP ++ + T E++ +RM+EQMY+IFY +SGPFGLYIMYH+
Sbjct: 138 FYMIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHS 197
Query: 192 DLWLFRTDTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHHI 251
DLWLF+T MY+TYP N +L+KIFYLGQAAFW QQ+CVL LQLEKPRKD++EL+FHHI
Sbjct: 198 DLWLFKTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHI 257
Query: 252 VTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLDSSLTPPFFLFFIVSWVYL 311
VTL LIW SYVFHFTKMGL++Y+TMDVSDFFLSLSKT NYL+S TP F F+ W+YL
Sbjct: 258 VTLLLIWSSYVFHFTKMGLAIYITMDVSDFFLSLSKTLNYLNSVFTPFVFGLFVFFWIYL 317
Query: 312 RHYINLKILWSLLTEFTTVGNYTLNFATQQYKCWISQPIIXXXXXXXXXXXXXXXXXIAR 371
RH +N++ILWS+LTEF GNY LNFATQQYKCWIS PI+ I R
Sbjct: 318 RHVVNIRILWSVLTEFRHEGNYVLNFATQQYKCWISLPIVFVLIAALQLVNLYWLFLILR 377
Query: 372 ILYRLVVHGIQKD 384
ILYRL+ GIQKD
Sbjct: 378 ILYRLIWQGIQKD 390
>SPBC3E7.15c [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 384
Score = 266 bits (680), Expect = 4e-71
Identities = 142/365 (38%), Positives = 210/365 (56%), Gaps = 19/365 (5%)
Query: 13 RRTTSIGRINLGDTSVPSLSTMSVTEESKHASEARLKLLSSSSEKDIDVLRKLWLSYREL 72
RR+ S N+ S S STM V + R K + + ++ VLR
Sbjct: 7 RRSQSQKFKNIPSISAGSFSTMPVQHRGRRR---RSKSIVGRAAQNA-VLR--------- 53
Query: 73 SYRHSWLTSLLIISVIYLFYICSGNRTASNPLHMFVAISYQIGDTN--MYGKGPKDLCFV 130
S +W+ L++++++ +Y + N + + +SY I TN YGKG D+ F
Sbjct: 54 SKEKTWIVPLILLTLLVGWYFVNPN----GYIKYGIFLSYPIPGTNPAQYGKGRLDIAFC 109
Query: 131 FFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFYYSISGPFGLYIMYH 190
FY +FFTF REFIMQ I+ + K+RR EQ Y+ Y+++ G +GLY+M
Sbjct: 110 LFYALFFTFCREFIMQEIIARIGRHFNIRAPAKLRRFEEQAYTCLYFTVMGSWGLYVMKQ 169
Query: 191 TDLWLFRTDTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHH 250
T +W F TD ++ YP F + +K FYL +AA+W QQ+ VL LQLEKPRKDF+EL+ HH
Sbjct: 170 TPMWFFNTDAFWEEYPHFYHVGSFKAFYLIEAAYWIQQALVLILQLEKPRKDFKELVVHH 229
Query: 251 IVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLDSSLTPPFFLFFIVSWVY 310
I+TL LI LSY FHFT +GL+V++TMD SD +L+LSK NY+++ + P F+ F+ W+Y
Sbjct: 230 IITLLLIGLSYYFHFTWIGLAVFITMDTSDIWLALSKCLNYVNTVIVYPIFVIFVFVWIY 289
Query: 311 LRHYINLKILWSLLTEFTTVGNYTLNFATQQYKCWISQPIIXXXXXXXXXXXXXXXXXIA 370
+RHY+N KI+W++ T+ ++ L++A +QYKCWIS+ + I
Sbjct: 290 MRHYLNFKIMWAVWGTMRTINSFDLDWAAEQYKCWISRDVTLILLTALQLVNIYWLILIL 349
Query: 371 RILYR 375
RI YR
Sbjct: 350 RIGYR 354
>SPAC1A6.09c [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 390
Score = 159 bits (402), Expect = 7e-39
Identities = 91/244 (37%), Positives = 132/244 (53%), Gaps = 5/244 (2%)
Query: 83 LIISVIYLFYICSGNRTASNPLHMFVAISYQIGDTNMYGKGPKDLCFVFFYMIFFTFLRE 142
+ +S+I + + C + + F+ +SY+ D + YGKGPKD CF F++I FT R
Sbjct: 72 ICLSIIAICFACLLSPSLRPYAEPFIFLSYKQPDGS-YGKGPKDACFPIFWVIVFTAFRV 130
Query: 143 FIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMY 202
+M + RP + G I R EQ YS FYY GLYI ++ W + ++
Sbjct: 131 IVMDYVFRPFVLNWGVRNRKVIIRFCEQGYSFFYYLCFWFLGLYIYRSSNYW-SNEEKLF 189
Query: 203 KTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYV 262
+ YP + L+K +YL Q FW QQ +L L LE+ R D ++ HHIVT ALI LSY
Sbjct: 190 EDYPQYYMSPLFKAYYLIQLGFWLQQ--ILVLHLEQRRADHWQMFAHHIVTCALIILSYG 247
Query: 263 FHFTKMGLSVYVTMDVSDFFLSLSKTFNYLD-SSLTPPFFLFFIVSWVYLRHYINLKILW 321
F+F ++G ++ D+SD+ LS K YL + F F+ SWVY RHY+ KIL
Sbjct: 248 FNFLRVGNAILYIFDLSDYILSGGKMLKYLGFGKICDYLFGIFVASWVYSRHYLFSKILR 307
Query: 322 SLLT 325
++T
Sbjct: 308 VVVT 311
>At1g13580 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 308
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/170 (33%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 160 RENKIRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMY-----KTYPDFNNEYLY 214
R+ KIR+ E + YY + L + Y+ + W T + +T+PD +
Sbjct: 68 RKKKIRKFKESAWKCVYYLSAEILALSVTYN-EPWFMNTKYFWVGPGDQTWPDQQTKLKL 126
Query: 215 KIFYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYV 274
K+ Y+ A F+T L E R DF + HHI TL LI LSYV F+++G V
Sbjct: 127 KLLYMFVAGFYTYSIFALVFW-ETRRSDFGVSMGHHIATLILIVLSYVCSFSRVGSVVLA 185
Query: 275 TMDVSDFFLSLSKTFNYLDSSLTPPF-FLFFIVSWVYLR-HYINLKILWS 322
D SD FL + K Y + F F+ F++SW+ LR Y ILWS
Sbjct: 186 LHDASDVFLEVGKMSKYSGAERIASFSFILFVLSWIILRLIYYPFWILWS 235
>At3g19260 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 296
Score = 79.0 bits (193), Expect = 1e-14
Identities = 47/163 (28%), Positives = 80/163 (48%), Gaps = 4/163 (2%)
Query: 151 PLSIKMGSTRENKIRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNN 210
P+ + +TR KI + E ++ + YY+ F L ++YH + W + +P+
Sbjct: 58 PIKLNDAATRA-KIVKCKESLWKLLYYAACDFFVLQVIYH-EPWARDIKLYFHGWPNQEL 115
Query: 211 EYLYKIFYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGL 270
+ K++Y+ Q F+ L L E RKDF ++ HH++T+ L+ SY+ F ++G
Sbjct: 116 KLSIKLYYMCQCGFYVYGVAAL-LAWETRRKDFAVMMSHHVITIILLSYSYLTSFFRIGA 174
Query: 271 SVYVTMDVSDFFLSLSKTFNYLDSSL-TPPFFLFFIVSWVYLR 312
+ D SD F+ +K F Y + F F VSW+ LR
Sbjct: 175 IILALHDASDVFMETAKIFKYSEKEFGASVCFALFAVSWLLLR 217
>At3g25540 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 310
Score = 77.4 bits (189), Expect = 4e-14
Identities = 64/222 (28%), Positives = 96/222 (42%), Gaps = 28/222 (12%)
Query: 125 KDLCFVFFYMIFFTFLREFIMQVILRPLS---------------IKMGSTRENKIRRMME 169
+DL F+ + +FF +R + + + L+ IK K+R+ E
Sbjct: 21 QDLGFLPLFAVFFPTIRFLLDRFVFEKLASLVIYGRMSTNKSDNIKDRKKNSPKVRKFKE 80
Query: 170 QMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMY-------KTYPDFNNEYLYKIFYLGQA 222
+ YY + L + Y+ + W ++T+Y + +PD + K Y+ A
Sbjct: 81 SAWKCIYYLSAELLALSVTYN-EPWF--SNTLYFWIGPGDQIWPDQPMKMKLKFLYMFAA 137
Query: 223 AFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFF 282
F+T L E R DF + HHI TL LI LSY+ T+ G + D SD F
Sbjct: 138 GFYTYSIFALVFW-ETRRSDFGVSMGHHITTLVLIVLSYICRLTRAGSVILALHDASDVF 196
Query: 283 LSLSKTFNYLDS-SLTPPFFLFFIVSWVYLR-HYINLKILWS 322
L + K Y + SL F+ F +SWV LR Y ILWS
Sbjct: 197 LEIGKMSKYCGAESLASISFVLFALSWVVLRLIYYPFWILWS 238
>CE27675 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 368
Score = 69.7 bits (169), Expect = 7e-12
Identities = 45/173 (26%), Positives = 87/173 (50%), Gaps = 6/173 (3%)
Query: 157 GSTRENKIRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKI 216
G ++ ++++E + YY+ + +GLY+M ++ WL+ + YP
Sbjct: 82 GFASVSRAKKILECFWRFSYYTFAFLYGLYVMKNSS-WLYDVKQCWIGYPFHPVPDTIWW 140
Query: 217 FYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTM 276
+Y+ + F+ S ++ + R DF +L+ HH++T+ L+ S+ +F ++G + ++
Sbjct: 141 YYMIETGFY--YSLLIGSTFDVRRSDFWQLMVHHVITIFLLSSSWTINFVRVGTLILLSH 198
Query: 277 DVSDFFLSLSKTFNY--LDSSLTPPFFLFFIVSWVYLR-HYINLKILWSLLTE 326
DVSD FL K Y + ++T F+ F SWV R Y ++ S +TE
Sbjct: 199 DVSDVFLEGGKLVRYDAHNKNMTNFMFVLFFSSWVATRLIYYPFIVIRSAVTE 251
>ECU08g1350 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 287
Score = 68.2 bits (165), Expect = 2e-11
Identities = 44/185 (23%), Positives = 87/185 (46%), Gaps = 7/185 (3%)
Query: 124 PKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRE---NKIRRMMEQMYSIFYYSIS 180
P+D+C + + T ++ I+ L ++G ++ K ++ ++ +YS +
Sbjct: 21 PRDICLTMVFSLLITMVKNLIVLPTASALIKRLGLEKDLGSEKKKKFCISLWKAMFYSFT 80
Query: 181 GPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPR 240
+G Y + ++ + + T+ FY + +++ + + L E
Sbjct: 81 SVYG-YFVIRSEPRAYTAKNLMDTWGVHGAPSKVLFFYHLEFSYYFVE--LFYLFSEHAY 137
Query: 241 KDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYL-DSSLTPP 299
KDF +++ HHIVT+ L++LSY + G+++ V D+SD FL + K NY+ D SL
Sbjct: 138 KDFLQMVTHHIVTMLLLFLSYHNDLLRAGVAIIVIHDISDPFLEIGKLTNYIHDKSLATS 197
Query: 300 FFLFF 304
F F
Sbjct: 198 IFTCF 202
>Hs13375717 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 394
Score = 63.9 bits (154), Expect = 4e-10
Identities = 42/154 (27%), Positives = 71/154 (45%), Gaps = 4/154 (2%)
Query: 160 RENKIRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKIFYL 219
R ++ E + +Y S GL ++YH + WL+ + YP+ + +YL
Sbjct: 126 RPQLTKKFCEASWRFLFYLSSFVGGLSVLYH-ESWLWAPVMCWDRYPNQTLKPSLYWWYL 184
Query: 220 GQAAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVS 279
+ F+ S ++ L + RKDF+E + HH V + L+ SY + ++G V + D S
Sbjct: 185 LELGFYL--SLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSS 242
Query: 280 DFFLSLSKTFNYLD-SSLTPPFFLFFIVSWVYLR 312
D+ L K NY+ + FL F + Y R
Sbjct: 243 DYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTR 276
>Hs11641421 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 350
Score = 63.2 bits (152), Expect = 7e-10
Identities = 55/212 (25%), Positives = 91/212 (41%), Gaps = 15/212 (7%)
Query: 124 PKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFYYSISGPF 183
P +L + + +T LR + RPL+ K + +M E + +Y S +
Sbjct: 57 PPELLLLALGALGWTALRSAATARLFRPLA-KRCCLQPRDAAKMPESAWKFLFYLGSWSY 115
Query: 184 GLYIMYHTDLWLFRT--DTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPRK 241
Y+++ TD F Y P YL Q +F+ S TL ++ RK
Sbjct: 116 SAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGH-SIYATLYMDTWRK 174
Query: 242 DFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSD----------FFLSLSKTFNY 291
D ++ HH+VTL LI SY F + +G+ V D+SD +F S +++
Sbjct: 175 DSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHR 234
Query: 292 LDSSLTPPFFLFFIVSWVYLR-HYINLKILWS 322
L + L F SW + R ++ LK+L++
Sbjct: 235 LHALAADLGCLSFGFSWFWFRLYWFPLKVLYA 266
>7290103 [U] KOG1608 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 368
Score = 61.2 bits (147), Expect = 3e-09
Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 2/156 (1%)
Query: 115 GDTNMYGKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSI 174
G Y G KD C +FFY + + I + +L +S K+ ++ K+ R E +
Sbjct: 74 GKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKF-KLARFNESGQLV 132
Query: 175 FYYSISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTL 234
+Y +S +G +++ +L + +++ +PD +L+K +++ Q A++ L
Sbjct: 133 AFYLLSFVWGAHVLLKEG-YLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYF 191
Query: 235 QLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGL 270
Q K +++ Q I H I LI L+Y F ++ L
Sbjct: 192 QKIKTKEEQQPKIVHSISGFTLIVLAYTLSFQRLAL 227
>Hs20550645 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 328
Score = 56.2 bits (134), Expect = 8e-08
Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 8/164 (4%)
Query: 164 IRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMYKTYPDFN--NEYLYKIFYLGQ 221
+ + E M+ +Y +G+ ++ + W + + YP F + LY + +
Sbjct: 57 LTKFCESMWRFTFYLCIFCYGIRFLWSSP-WFWDIRQCWHNYP-FQPLSSGLYHYYIMEL 114
Query: 222 AAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDF 281
A +W+ T + RKDF + HH+VT+ LI SY+ + ++G + DVSDF
Sbjct: 115 AFYWSLMFSQFT---DIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDF 171
Query: 282 FLSLSKTFNYLDSSLTPPFFLFFIVSWVYLRHYINLKILWSLLT 325
L +K NY LF I S V++ + + W L T
Sbjct: 172 LLEAAKLANYAKYQRLCD-TLFVIFSAVFMVTRLGIYPFWILNT 214
>CE20184 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 360
Score = 55.8 bits (133), Expect = 1e-07
Identities = 59/237 (24%), Positives = 97/237 (40%), Gaps = 32/237 (13%)
Query: 111 SYQIGDTNMYGKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGS-TRENKI----- 164
S I D +L V FTFLR + L I++ S T+++ I
Sbjct: 50 SSMISDFKKVSLSNSELYTVLILASIFTFLRYY--------LQIRLESWTQQHNIYPRFA 101
Query: 165 RRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTD--TMYKTYPDFNNEYLY---KIFYL 219
++ E + + YY F Y D D +M+ + ++ ++ Y
Sbjct: 102 HKVPESFWKLTYYGTVWIFAFYFHMCVDSHDIFNDPLSMWIEWESGGRPKMHWQVQVIYA 161
Query: 220 GQAAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVS 279
Q+AF+ S TL ++ RKD + HH + L L++LSYV +FT G V D S
Sbjct: 162 VQSAFYIH-SIYATLFMDLWRKDSWLMFVHHFIALGLLFLSYVDNFTLPGALVLFLHDNS 220
Query: 280 DFFLSLSKTFNYLDSSLTPPF-----------FLFFIVSWVYLR-HYINLKILWSLL 324
D L ++K YL + F+ F + WV R ++ K+L++ +
Sbjct: 221 DATLEITKLSFYLKKRTNRQYYKYYFLMGNAAFILFAIIWVIFRLYWYTCKLLYATI 277
>Hs17444463 [U] KOG1608 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 369
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/192 (23%), Positives = 84/192 (43%), Gaps = 3/192 (1%)
Query: 115 GDTNMYGKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSI 174
G ++Y G KDL VFFYM+ + I + +L ++ +M T+ + + +S+
Sbjct: 68 GSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQFSV 127
Query: 175 FYYSISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTL 234
FY+ S +G +I+ ++ L ++K P + K FY+ Q A+W L
Sbjct: 128 FYF-FSCIWGTFILI-SENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELYF 185
Query: 235 QLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLDS 294
Q K ++D + + + L I +Y+ + +GL + V + + F + D
Sbjct: 186 QKTK-KQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSDE 244
Query: 295 SLTPPFFLFFIV 306
L+ IV
Sbjct: 245 KYQKGISLWAIV 256
>Hs6912450 [U] KOG1608 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 370
Score = 53.9 bits (128), Expect = 4e-07
Identities = 48/222 (21%), Positives = 99/222 (43%), Gaps = 11/222 (4%)
Query: 106 MFVAISYQIG------DTNMYGKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGST 159
+F+ Y I +T Y GPKDL + FY+ L + + IL +S ++ +
Sbjct: 48 LFILPQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLS 107
Query: 160 RENKIRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKIFYL 219
+ K + E + ++ S + Y++ T+ +L ++++ YP + + K FYL
Sbjct: 108 KV-KHSKFNESGQLVVFHFTSVIWCFYVVV-TEGYLTNPRSLWEDYPHVHLPFQVKFFYL 165
Query: 220 GQAAFWTQQSCVLTLQLEKPRK-DFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDV 278
Q A+W + L +K RK + + + + L I +Y+ + +++GL + +
Sbjct: 166 CQLAYWLH--ALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYS 223
Query: 279 SDFFLSLSKTFNYLDSSLTPPFFLFFIVSWVYLRHYINLKIL 320
++F ++ F + D + F + V V + L +L
Sbjct: 224 TEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVL 265
>Hs9937998 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 230
Score = 53.1 bits (126), Expect = 7e-07
Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 9/123 (7%)
Query: 194 WLFRTDTMYKTYP---DFNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHH 250
W + +++ YP ++Y Y + L + +W S + ++ + RKDF+E I HH
Sbjct: 9 WFYDMKKVWEGYPIQSTIPSQYWYYMIEL--SFYW---SLLFSIASDVKRKDFKEQIIHH 63
Query: 251 IVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLD-SSLTPPFFLFFIVSWV 309
+ T+ LI S+ ++ + G + D SD+ L +K FNY + F+ F + ++
Sbjct: 64 VATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFI 123
Query: 310 YLR 312
R
Sbjct: 124 ITR 126
>Hs7657655 [U] KOG1608 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 374
Score = 53.1 bits (126), Expect = 7e-07
Identities = 51/232 (21%), Positives = 101/232 (42%), Gaps = 18/232 (7%)
Query: 118 NMYGKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFYY 177
++Y G KDL VFFYM+ + I + +L ++ +M ++ K + E +Y
Sbjct: 71 SLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSK-TKHSKFNESGQLSAFY 129
Query: 178 SISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNNEYLYKIFYLGQAAFWTQQSCVLTLQLE 237
+ +G +I+ ++ ++ +++ YP + K FY+ Q A+W L Q
Sbjct: 130 LFACVWGTFILI-SENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKT 188
Query: 238 KPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLDSSLT 297
K ++D + + + L I +Y+ + +GL + V +F +S+ F + +
Sbjct: 189 K-KEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQ 247
Query: 298 PPFFLFFIVSWVYLRHYINLKILWSLLTEFTTVG-------NYTLNFATQQY 342
F L+ ++ L L +L+ TVG N L+F+T +
Sbjct: 248 KGFSLWAVL--------FVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNF 291
>CE18518 [U] KOG1608 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 373
Score = 53.1 bits (126), Expect = 7e-07
Identities = 44/198 (22%), Positives = 95/198 (47%), Gaps = 7/198 (3%)
Query: 120 YGKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFY--Y 177
Y G DL +FFY + + + + + L +S K ++ + + E + +F+ Y
Sbjct: 79 YLSGILDLPAIFFYSVCWIVVHAVVQEYGLDKISKKTHLSKVSTFK-FGESFHQMFFTVY 137
Query: 178 SISGPFGLYIMYHTDLWLFRTDTMYKTYPDFNN--EYLYKIFYLGQAAFWTQQSCVLTLQ 235
SI+ F + D ++ +++ YP + YK++++ Q ++W Q LQ
Sbjct: 138 SIAHAFYIVSERLEDFSEVKSFSVWLGYPTEHRVMSAAYKLYFIFQISYWIHQFPEFYLQ 197
Query: 236 LEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLD-S 294
K R + ++ I+ +A I ++Y F+FT++GL++ ++ +++ +++
Sbjct: 198 KLK-RDEIRQKSVQAILHIAFISIAYFFNFTRVGLALITLEYITQLIFHIARFAHFVGRK 256
Query: 295 SLTPPFFLFFIVSWVYLR 312
L+ P F F S+V +R
Sbjct: 257 GLSDPAFKLFNGSFVLVR 274
>Hs20481895 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 293
Score = 51.6 bits (122), Expect = 2e-06
Identities = 38/136 (27%), Positives = 65/136 (46%), Gaps = 9/136 (6%)
Query: 191 TDLWLFRTDTMYKTYPD---FNNEYLYKIFYLGQAAFWTQQSCVLTLQLEKPRKDFQELI 247
T WL+ ++ YP ++Y Y I L + +W S + L + RKDF I
Sbjct: 69 TKPWLYDLWEVWNGYPKQPLLPSQYWYYI--LEMSFYW---SLLFRLGFDVKRKDFLAHI 123
Query: 248 FHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLDSSLTPPFFLFFIVS 307
HH+ ++L+ S+ ++ + G V + DV+D +L +K F+Y + T LFFI S
Sbjct: 124 IHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLESAKMFSYAGWTQTCN-TLFFIFS 182
Query: 308 WVYLRHYINLKILWSL 323
++ + + W L
Sbjct: 183 TIFFISRLIVFPFWIL 198
>CE18517 [U] KOG1608 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 371
Score = 51.2 bits (121), Expect = 3e-06
Identities = 42/196 (21%), Positives = 90/196 (45%), Gaps = 5/196 (2%)
Query: 120 YGKGPKDLCFVFFYMIFFTFLREFIMQVILRPLSIKMGSTRENKIRRMMEQMYSIFYYSI 179
Y G DL +FFY + + + + + L +S K ++ + + E + +F+
Sbjct: 79 YLSGILDLPAIFFYSVCWIVVHAVVQEYGLDKISKKTHLSKVSTFK-FGESFHQMFFTVY 137
Query: 180 SGPFGLYIMYHTDLWLFRTDTMYKTYPDFNN--EYLYKIFYLGQAAFWTQQSCVLTLQLE 237
S YI+ +++ YP + YK++++ Q ++W Q LQ
Sbjct: 138 SIAHAFYIVSERLEDFSEVKSVWLGYPTEHRVMSAAYKLYFIFQISYWIHQFPEFYLQKL 197
Query: 238 KPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTMDVSDFFLSLSKTFNYLD-SSL 296
K R + ++ I+ +A I ++Y F+FT++GL++ ++ +++ +++ L
Sbjct: 198 K-RDEIRQKSVQAILHIAFISIAYFFNFTRVGLALITLEYITQLIFHIARFAHFVGRKGL 256
Query: 297 TPPFFLFFIVSWVYLR 312
+ P F F S+V +R
Sbjct: 257 SDPAFKLFNGSFVLVR 272
>Hs20532972 [U] KOG1607 Protein transporter of the TRAM (translocating
chain-associating membrane) superfamily
Length = 252
Score = 50.1 bits (118), Expect = 6e-06
Identities = 31/131 (23%), Positives = 65/131 (48%), Gaps = 9/131 (6%)
Query: 160 RENKIRRMMEQMYSIFYYSISGPFGLYIMYHTDLWLFRTDTMYKTYP---DFNNEYLYKI 216
R + +++ E + +Y I+ G+ ++ W + +++ YP ++Y Y +
Sbjct: 126 RPSLLKKFREASWRFTFYLIAFIAGMAVIVDKP-WFYDMKKVWEGYPIQSTIPSQYWYYM 184
Query: 217 FYLGQAAFWTQQSCVLTLQLEKPRKDFQELIFHHIVTLALIWLSYVFHFTKMGLSVYVTM 276
L + +W S + ++ + RKDF+E I HH+ T+ LI S+ ++ + G +
Sbjct: 185 IEL--SFYW---SLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALH 239
Query: 277 DVSDFFLSLSK 287
D SD+ L +S+
Sbjct: 240 DSSDYLLEVSQ 250
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.328 0.140 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,299,119
Number of Sequences: 60738
Number of extensions: 891368
Number of successful extensions: 2802
Number of sequences better than 1.0e-05: 22
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2777
Number of HSP's gapped (non-prelim): 22
length of query: 408
length of database: 30,389,216
effective HSP length: 109
effective length of query: 299
effective length of database: 23,768,774
effective search space: 7106863426
effective search space used: 7106863426
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)