ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3461 suspect: HSP O KOG0170 Posttranslational modification, protein turnover, chaperones E3 ubiquitin protein ligase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3461 1186427 1190827 1467
(1467 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase 519 e-146
YKL010c_1 [O] KOG0168 Putative ubiquitin fusion degradation protein 430 e-120
SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase 306 2e-82
At4g38600 [O] KOG0170 E3 ubiquitin protein ligase 298 4e-80
Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase 286 1e-76
At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase 265 4e-70
CE17508 [R] KOG4276 Predicted hormone receptor interactor 236 3e-61
7297647 [R] KOG4276 Predicted hormone receptor interactor 132 3e-30
Hs15300020 [R] KOG4276 Predicted hormone receptor interactor 132 5e-30
Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 117 1e-25
Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase 116 2e-25
Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase 116 2e-25
Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase 116 2e-25
YGL141w [O] KOG0942 E3 ubiquitin protein ligase 111 1e-23
At3g17205 [O] KOG0942 E3 ubiquitin protein ligase 107 1e-22
At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 103 2e-21
At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 102 6e-21
SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative up... 101 1e-20
SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase 100 3e-20
Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase 99 5e-20
CE19147 [O] KOG4427 E3 ubiquitin protein ligase 97 2e-19
CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 94 1e-18
SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 94 2e-18
ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 93 4e-18
7295004 [O] KOG4427 E3 ubiquitin protein ligase 92 5e-18
7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 92 5e-18
7291760 [O] KOG0942 E3 ubiquitin protein ligase 92 5e-18
SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 92 6e-18
YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 92 8e-18
Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 92 8e-18
Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 92 8e-18
CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 92 8e-18
Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 91 2e-17
CE15744 [O] KOG0942 E3 ubiquitin protein ligase 90 3e-17
7294742 [O] KOG0941 E3 ubiquitin protein ligase 90 3e-17
HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 89 5e-17
Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 89 5e-17
7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 89 5e-17
ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase 89 7e-17
Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 87 2e-16
At3g53090 [O] KOG4427 E3 ubiquitin protein ligase 86 3e-16
7292061 [O] KOG0941 E3 ubiquitin protein ligase 86 3e-16
7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 84 1e-15
HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 84 2e-15
Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 84 2e-15
YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 84 2e-15
SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase 84 2e-15
Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 84 2e-15
SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 83 3e-15
Hs10863903_1 [O] KOG0168 Putative ubiquitin fusion degradation p... 82 5e-15
Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 81 1e-14
CE29116 [O] KOG0941 E3 ubiquitin protein ligase 81 1e-14
7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 81 1e-14
At4g38610 [O] KOG0168 Putative ubiquitin fusion degradation protein 80 2e-14
Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase 79 4e-14
Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase 79 5e-14
7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 78 9e-14
Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 75 6e-13
7296816 [O] KOG0168 Putative ubiquitin fusion degradation protein 75 6e-13
YJR036c [O] KOG0941 E3 ubiquitin protein ligase 75 8e-13
Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase 72 7e-12
Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase 72 9e-12
Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase 72 9e-12
Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 70 3e-11
CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 67 2e-10
Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 67 2e-10
CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 67 2e-10
7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 67 3e-10
At5g02880_1 [O] KOG0168 Putative ubiquitin fusion degradation pr... 67 3e-10
Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 65 6e-10
Hs4557026 [S] KOG1426 FOG: RCC1 domain 65 8e-10
Hs4758520 [S] KOG1426 FOG: RCC1 domain 64 2e-09
Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperp... 63 4e-09
CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplas... 58 1e-07
At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 57 2e-07
>YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 470
Score = 519 bits (1336), Expect = e-146
Identities = 271/476 (56%), Positives = 347/476 (71%), Gaps = 18/476 (3%)
Query: 1004 YVNPKISAKLSRQLEEPLIVACGVLPSWVLDITRKYGFLFPFETRMNFLQNTSYGYGRLI 1063
++N K+SAKL+RQL+EPL+VA G LP W L +TR++ FLFPF+TRM FLQ TS+GYGRLI
Sbjct: 1 FINSKLSAKLARQLDEPLVVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLI 60
Query: 1064 QYWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNVLEIEY 1123
Q W+ K E L QLGR+TR KLR+SR ++F +G+KIL KYGSSP+VLEIEY
Sbjct: 61 QLWKNKSKGSKDLRNDE-ALQQLGRITRRKLRISRKTIFATGLKILSKYGSSPDVLEIEY 119
Query: 1124 KDEEGTGLGPTLEFYSLMSKEFARKSLKMWKTNS---------DTSDDEEEYVTGALFPG 1174
++E GTGLGPTLEFYS++SK FARKSL MW+ NS DT+DD Y+T LFP
Sbjct: 120 QEEAGTGLGPTLEFYSVVSKYFARKSLNMWRCNSYSYRSEMDVDTTDD---YITTLLFPE 176
Query: 1175 PLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDL-ED 1233
PL NNEK ++LF LGT VARS+LDNRILDFRF+ VFFEL+H+ + + D
Sbjct: 177 PL--NPFSNNEKVIELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSD 234
Query: 1234 FETCIHLVGQFDVQLGKSLAFLYDNRHDD-SIKNLDLYFMLPGYD-IELLEGGSKILVES 1291
ETC+ ++ D L KSL ++ N+ D+ ++++L L F +PG D IEL+ GG + S
Sbjct: 235 VETCLLMIELVDPLLAKSLKYIVANKDDNMTLESLSLTFTVPGNDDIELIPGGCNKSLNS 294
Query: 1292 FNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSV 1351
NVEEY+ V DQ LGKG++ QL AF GFSK F Y +LIL P EL D+FG V EDWS+
Sbjct: 295 SNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSM 354
Query: 1352 QTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKF 1411
TLY++++A+HGY+MDS II D I I+S F ++RLFLQF+TGSPKLP+GGFK+L PKF
Sbjct: 355 ATLYTNLNAEHGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKF 414
Query: 1412 TVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLLS 1467
TVVLKH + ++AD LPSVMTCANYLKLPKY+ K +++ R+ QA+ EG+GAFLLS
Sbjct: 415 TVVLKHAEDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS 470
>YKL010c_1 [O] KOG0168 Putative ubiquitin fusion degradation protein
Length = 1013
Score = 430 bits (1106), Expect = e-120
Identities = 287/919 (31%), Positives = 454/919 (49%), Gaps = 66/919 (7%)
Query: 100 LQDIVSRLADQRSGESGDGDVAEGEEADSERAFGRSLPDLLQELG-RSEGFFGVSRGNSR 158
L+ RL +R G G + GR+LP++L +G R E S N R
Sbjct: 122 LETFAQRLEQRRQTSEGLG----------QHPVGRTLPEILSMIGGRMERSAESSARNER 171
Query: 159 YLKLIENVLQAEDDPYIAMESLRELSEQLLMLNPLIADRIIPSGKLMDALIHVXXXXXXX 218
KLIEN A +DPYIAMESL+ELSE +LM+N ++ DRIIP L+ + +
Sbjct: 172 ISKLIENTGNASEDPYIAMESLKELSENILMMNQMVVDRIIPMETLIGNIAAILSDKILR 231
Query: 219 XXXXXXXIACRCLYNYYEMNPEMIEVSVNRDIIEILRGKLNEISYIDLAEQVLECLEFIS 278
ACRC+YN +E+ PE I ++V+ +I IL+GKL EISYIDLAEQVLE +E+IS
Sbjct: 232 EELELQMQACRCMYNLFEVCPESISIAVDEHVIPILQGKLVEISYIDLAEQVLETVEYIS 291
Query: 279 RVHGSKILRSGTLLSCLQYLDFFTVHAQKKSLSIVANSCARAKESDFEVVSEIFPILKSI 338
RVHG IL++G L +Q+ DF T+HAQ+K+++IV+N+C+ + DF+ + E+ P LK I
Sbjct: 292 RVHGRDILKTGQLSIYVQFFDFLTIHAQRKAIAIVSNACSSIRTDDFKTIVEVLPTLKPI 351
Query: 339 FLNSTNPVILKPVLITLYXX-XXXXXXXXXXXXFDFXXXXXXXXXXXXXXXXXXXXXKVL 397
F N+T+ IL ++ +Y F K L
Sbjct: 352 FSNATDQPILTRLVNAMYGICGALHGVDKFETLFSLDLIERIVQLVSIQDTPLENKLKCL 411
Query: 398 DISSLLVSTNVELSKQILLDCELNKVIQNVFQSYKKSASSTFSETLIYVPKEXXXXXXXX 457
DI ++L ++ LS+++ ++ + FQ Y KS ++ ETLIYVP
Sbjct: 412 DILTVLAMSSDVLSRELREKTDIVDMATRSFQHYSKSPNAGLHETLIYVPNSLLISISRF 471
Query: 458 XXXXXXXEDSQILTADEVKVFTFDG---NEDKFLELVNELIPCLVEIYSNTVDTKIRYTV 514
ED +IL+AD+ + G N++KF LV LIP LVEIY+N D +R V
Sbjct: 472 IVVLFPPEDERILSADKYTGNSDRGVISNQEKFDSLVQCLIPILVEIYTNAADFDVRRYV 531
Query: 515 LVALARVFTSIPHGYDXXXXXXXXXXXXXXXXXXXAQQD-------HMKTETXXXXXXXX 567
L+AL RV + I + AQ++ +E
Sbjct: 532 LIALLRVVSCI----NNSTAKAINDQLIKLIGSILAQKETASNANGTYSSEAGTLLVGGL 587
Query: 568 XXXXXXXXNNPDLYLPKLRKEGIPDALTSLNSHYSYELSKKDSIDKQESSSDEAEKSGYH 627
+L+ P +++EGI D + L+ ++ K+D E+ S E+ H
Sbjct: 588 SLLDLICKKFSELFFPSIKREGIFDLVKDLSVDFNNIDLKEDG---NENISLSDEEGDLH 644
Query: 628 IRPENSDSHPVFGXXXXXXXXXXXXXXXXYRMEYDDMNIPEFVKPRKIRINIYDHLTPYY 687
E D Y E+ DM IP+ VKP+KI I+I+ L+ Y
Sbjct: 645 SSIEECDE-----------------GDEEYDYEFTDMEIPDSVKPKKISIHIFRTLSLAY 687
Query: 688 L-IKHVSMFSATLLELFSSNQEEVSSELSEINAVVTKMKELDVQSDSEQYWMDFWTAVKS 746
+ K V++ + L ++ + QE ++ EL +I VV+ ++ +E+ W W+ +K
Sbjct: 688 IKNKGVNLVNRVLSQM-NVEQEAITEELHQIEGVVSILENPSTPDKTEEDWKGIWSVLKK 746
Query: 747 SLFDDMSNISGFELISTGLIDSMANIFETDSTKQSFSKRTFLKVFEEKLPEFVKLLQNAL 806
+F + ++SGFE STGL S+ + + ++FL+VFE+ + F+++LQ+AL
Sbjct: 747 CIFHEDFDVSGFEFTSTGLASSITKRITSSTVSHFILAKSFLEVFEDCIDRFLEILQSAL 806
Query: 807 SRTETFAILDAGASSNDSPSASLIKQMKIRLVHEPADDEVGKDTVPETLQDVVIAVHCVA 866
+R E F+I+D G S SL K++KI+LV+ D + KD + L +++VHC+A
Sbjct: 807 TRLENFSIVDCGLHDGGGVS-SLAKEIKIKLVY---DGDASKDNIGTDLSSTIVSVHCIA 862
Query: 867 SLKTLDEFLKHKIVQSEFLTSIIPSMSRANQQAN---PTNVAKELENIQFDFSLNDHLLD 923
S +L+EFL+H++V+ FL S+IP+++ ++ +A+ N + FDF ++ +D
Sbjct: 863 SFTSLNEFLRHRMVRMRFLNSLIPNLTSSSTEADREEEENCLDHMRKKNFDFFYDNEKVD 922
Query: 924 QSSTIYSIIFKEAMKEGLPTTSIWTNVPTFKFKKSV-----------KRRESHQLHVLYP 972
ST++ +IF ++ ++W + T KF KS+ + E +L Y
Sbjct: 923 MESTVFGVIFNTFVRRNRDLKTLWDDTHTIKFCKSLEGNNRESEAAEEANEGKKLRDFYK 982
Query: 973 DTAFEGADLKPVNGILTVL 991
F D ILT+L
Sbjct: 983 KREFAQVDTGSSADILTLL 1001
>SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase
Length = 400
Score = 306 bits (784), Expect = 2e-82
Identities = 180/395 (45%), Positives = 238/395 (59%), Gaps = 28/395 (7%)
Query: 1085 QLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNVLEIEYKDEEGTGLGPTLEFYSLMSKE 1144
Q L R K+R+SR +F + +L Y +S N+LEIEY+DE G+GLGPTLEFY+ +SKE
Sbjct: 22 QFVSLHRQKIRISRKKIFNYALHLLATYAASENILEIEYEDEVGSGLGPTLEFYTSVSKE 81
Query: 1145 FARKSLKMWKTNSDTSDDEEEYVTGALFPGP--LLGTTEENNEKTLKLFENLGTLVARSM 1202
F SL +W+ +D + + Y LFP P LLG++ EN E+ + LF LG VARS+
Sbjct: 82 FTLNSLDIWR--NDQPNSKFVYQASGLFPSPIPLLGSSPEN-ERKISLFFALGQFVARSI 138
Query: 1203 LDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLY------ 1256
D+RI+ +FN +FF + I V + D L SL +L
Sbjct: 139 YDSRIISIQFNPLFFA-------------RNIPLTISSVAKVDKGLANSLRYLEKLIPGK 185
Query: 1257 ---DNRHDDSIKNLDLYFMLPGY-DIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDM 1312
+ D +++L L F LPG+ IEL+ G+ V +FNV +YL V D +GKGV
Sbjct: 186 NPTNAETDIKLEDLHLDFTLPGFPSIELIPDGASTPVTTFNVSDYLNYVIDYTVGKGVQQ 245
Query: 1313 QLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIIT 1372
QL AF+NGFS FPY+SL +LT EL LFG V EDWS TL SI ADHGY+M+SP I
Sbjct: 246 QLEAFQNGFSSVFPYTSLQVLTEHELVTLFGTVDEDWSYATLMKSIVADHGYTMESPTIQ 305
Query: 1373 DLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVM 1432
L+ ++S + Q++R FLQFITGS KLP+GGF L P TVV + + D LPSVM
Sbjct: 306 RLLTLMSQMNFQEQRDFLQFITGSRKLPIGGFAGLNPPLTVVRRLNEPPYVPDDYLPSVM 365
Query: 1433 TCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLLS 1467
TC NYLKLP+YS VL R+++A+ EG G+F LS
Sbjct: 366 TCVNYLKLPEYSSSEVLGSRLSKAILEGQGSFHLS 400
>At4g38600 [O] KOG0170 E3 ubiquitin protein ligase
Length = 757
Score = 298 bits (763), Expect = 4e-80
Identities = 192/523 (36%), Positives = 281/523 (53%), Gaps = 70/523 (13%)
Query: 999 LPASIYVNPKISAKLSRQLEEPLIVACGVLPSWVLDITRKYGFLFPFETRMNFLQNTSYG 1058
+P +VN K++ KL+RQ+++ L + G LPSW +TR FLFPF+TR + +T++G
Sbjct: 251 VPLDEFVNSKLTPKLARQIQDALALCSGSLPSWCYQLTRACPFLFPFQTRRQYFYSTAFG 310
Query: 1059 YGRLIQYWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNV 1118
R + +++ + E + ++GRL R K+RVSR+ + S K+++ Y S V
Sbjct: 311 LSRALNRLQQQQGADGSGSTNEREM-RIGRLQRQKVRVSRNRILDSAAKVMEMYSSQKAV 369
Query: 1119 LEIEYKDEEGTGLGPTLEFYSLMSKEFARKSLKMWKTNSDTS-------DDEEEYVTGA- 1170
LE+EY E GTGLGPTLEFY+L+S + + SL MW+++S D+ E+ A
Sbjct: 370 LEVEYFGEVGTGLGPTLEFYTLLSHDLQKASLGMWRSSSGDKVSMQIGRDEIEDGKPSAA 429
Query: 1171 ----------LFPGPLLGTTEENN----EKTLKLFENLGTLVARSMLDNRILDFRFNAVF 1216
LFP P T + + K ++ F LG ++A+++ D R+LD + F
Sbjct: 430 NRDIVLAPLGLFPRPWPSTADISEGGQFHKVIEYFRLLGRVMAKALQDGRLLDVPLSTAF 489
Query: 1217 FELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLY--------------DNRHDD 1262
++L+ LDL D + FD +LGK+L L DN
Sbjct: 490 YKLI----LGQELDLHD-------IVLFDAELGKTLQELRVVVARKHYLEGVGGDNSSTI 538
Query: 1263 S--------IKNLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQL 1314
S I++L L F LPGY +L G +I V+ N+EEY+ V D + +GV Q+
Sbjct: 539 SDLCLRGCRIEDLSLEFTLPGYPEYILRSGDEI-VDITNLEEYISLVVDATVKRGVTRQI 597
Query: 1315 AAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDL 1374
AFR+GF++ F +SL I TP+EL L E W V+TL I DHGY+ SP I
Sbjct: 598 EAFRSGFNQVFDITSLQIFTPSELDYLLCGRRELWEVETLAEHIKFDHGYNAKSPAI--- 654
Query: 1375 IDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPD----------GNISA 1424
I++ S+ Q+R F QF+TG+P+LP GG L PK T+V KH + +A
Sbjct: 655 INVCYPSSSDQQRAFCQFVTGAPRLPPGGLAVLNPKLTIVRKHSSTSSAAANGAGASETA 714
Query: 1425 DHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLLS 1467
D LPSVMTCANYLKLP YS K ++ ++ A+ EG G+F LS
Sbjct: 715 DDDLPSVMTCANYLKLPPYSTKEIMYKKLLYAINEGQGSFDLS 757
>Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 650
Score = 286 bits (733), Expect = 1e-76
Identities = 178/497 (35%), Positives = 277/497 (54%), Gaps = 30/497 (6%)
Query: 999 LPASIYVNPKISAKLSRQLEEPLIVACGVLPSWVLDITRKYGFLFPFETRMNFLQNTSYG 1058
+P S ++N K++AK +RQL++PL++ G +P+W+ ++ + F FPF+TR T++
Sbjct: 156 IPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFD 215
Query: 1059 YGRLIQYWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNV 1118
R +Q + + + S+ ++ + RL R K V+R+ L +++ GSS +
Sbjct: 216 RDRAMQRLLDTNPEINQSDSQDSRVAP--RLDRKKRTVNREELLKQAESVMQDLGSSRAM 273
Query: 1119 LEIEYKDEEGTGLGPTLEFYSLMSKEFARKSLKMWK------TNSDTSDDEEEYVTG--A 1170
LEI+Y++E GTGLGPTLEFY+L+S+E R L +W+ +N S + +Y+
Sbjct: 274 LEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQG 333
Query: 1171 LFPGPLLGTTEENNEKTLKL-FENLGTLVARSMLDNRILDFRFNAVFFELMHK----CCK 1225
LF P T + + +K+ F LG L+A++++D R++D F++ M +
Sbjct: 334 LFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTS 393
Query: 1226 NDRLD-----------LEDFETCIHLVGQFDVQLGKSLAFLYDN--RHDDSIKNLDLYFM 1272
+D D LED + Q Q +SL + + + S+++L L F
Sbjct: 394 HDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFT 453
Query: 1273 LPGY-DIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLL 1331
LPG+ +IEL +GG I V N+EEYL V L +GV Q +FR+GF FP S L
Sbjct: 454 LPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQ 513
Query: 1332 ILTPTELSDLF-GAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFL 1390
P EL L G+ A+ W +TL DHGY+ DS + L +ILS+F +Q+RLFL
Sbjct: 514 YFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFL 573
Query: 1391 QFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLK 1450
QF+TGSP+LP+GGF++L P T+V K + + D LPSVMTC NYLKLP YS +++
Sbjct: 574 QFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMR 633
Query: 1451 DRIAQAMTEGSGAFLLS 1467
+++ A EG +F LS
Sbjct: 634 EKLLIAAREGQQSFHLS 650
>At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 628
Score = 265 bits (677), Expect = 4e-70
Identities = 171/494 (34%), Positives = 265/494 (53%), Gaps = 32/494 (6%)
Query: 995 QHKSLPASIYVNPKISAKLSRQLEEPLIVACGVLPSWVLDITRKYGFLFPFETRMNFLQN 1054
Q + +P S +V+ K++ KL +QL + V+ LP W D+ LF FE + + +
Sbjct: 146 QVRPVPHSEFVSSKLTEKLEQQLRDSFAVSTCGLPPWFNDLMDSCPCLFSFEAKSKYFRL 205
Query: 1055 TSYGYGRLIQYWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGS 1114
++G ++ + + + H P+ G L R K R+++ S K+++ YG+
Sbjct: 206 AAFGSQKIRHHPQHLSSSNVHGEA--RPV--TGSLPRKKFLACRENILESAAKMMELYGN 261
Query: 1115 SPNVLEIEYKDEEGTGLGPTLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGAL--- 1171
V+E+EY +E GTGLGPTLEFY+L+S+ F L MW+ + + +G L
Sbjct: 262 QKVVIEVEYSEEVGTGLGPTLEFYTLVSRAFQNPDLGMWRNDCSFIVGKPVEHSGVLASS 321
Query: 1172 ---FPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFEL-MHKCCKND 1227
FP P GT+ ++ L+ F LGT+VA+++ D R+LD + F++L + + +
Sbjct: 322 SGLFPRPWSGTSTTSD--VLQKFVLLGTVVAKALQDGRVLDLPLSKAFYKLILGQELSSF 379
Query: 1228 RLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDS-------------IKNLDLYFMLP 1274
+ D E C LV ++Q L+ H DS I++L L F LP
Sbjct: 380 DIHFVDPELCKTLV---ELQALVRRKKLFAEAHGDSGAAKCDLSFHGTKIEDLCLEFALP 436
Query: 1275 GY-DIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLIL 1333
GY D +L + +V N+EEY+ + + + G+ Q+ AFR+GF++ F L I
Sbjct: 437 GYTDYDLAPYSANDMVNLDNLEEYIKGIVNATVCNGIQKQVEAFRSGFNQVFSIEHLRIF 496
Query: 1334 TPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFI 1393
EL + + +S+ + I DHGY+ SP + L+ IL F +Q+R FLQF+
Sbjct: 497 NEEELETMLCGECDLFSMNEVLDHIKFDHGYTSSSPPVEYLLQILHEFDREQQRAFLQFV 556
Query: 1394 TGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRI 1453
TGSP+LP GG +L PK T+V KH G+ S+D LPSVMTCANYLKLP YS K +K+++
Sbjct: 557 TGSPRLPHGGLASLSPKLTIVRKH--GSDSSDTDLPSVMTCANYLKLPPYSSKEKMKEKL 614
Query: 1454 AQAMTEGSGAFLLS 1467
A+TEG G+F LS
Sbjct: 615 IYAITEGQGSFHLS 628
>CE17508 [R] KOG4276 Predicted hormone receptor interactor
Length = 2761
Score = 236 bits (601), Expect = 3e-61
Identities = 169/558 (30%), Positives = 279/558 (49%), Gaps = 88/558 (15%)
Query: 981 LKPVNGILTVLQCCQHKSLPASIYVNPKISAKLSRQLEEPLIVACGVLPSWVLDITRKYG 1040
L+ + + + Q + +++++ K++ K+++ L + L+VA LP W + KY
Sbjct: 2207 LETIGLLSRIQQAMPEAEITPNVFISDKLTLKVTQVLSDALVVAARSLPEWCSRLVYKYP 2266
Query: 1041 FLFPFETRMNFLQNTSYGYGRLIQYWREKL-----------------ADQHHSNPTENPL 1083
LF ETR ++Q T++G R I + +++ A + H E
Sbjct: 2267 CLFTVETRNMYMQATAFGVSRTIVWLQQRRDAAVERARGSAQAGNSSAARQHDRYHE--- 2323
Query: 1084 HQLGRLTRHKLRVSR--DSLFLSGIKILKKYGSSPNVLEIEYKDEEGTGLGPTLEFYSLM 1141
+++GRL +++V+R ++L I+++K + VLEIEY +EEGTGLGPTLEFY+L+
Sbjct: 2324 YRVGRLRHERVKVTRAEETLLDQAIRLMKFHADRKAVLEIEYTNEEGTGLGPTLEFYALV 2383
Query: 1142 SKEFARKSLKMW-----KTNSDTSDDEEE------------YV--TGALFPGPLLGTTEE 1182
+ E RKSL +W T++ S +E E YV G LFP PL T+E
Sbjct: 2384 AAELQRKSLALWVCDDDDTHASKSGEEREVDLGEGKKPIGYYVRRVGGLFPAPLPPGTDE 2443
Query: 1183 NNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELM-HKCCKNDR--------LDLED 1233
++ +F LG +A+ +LD R++D + F +L+ H +D L L+D
Sbjct: 2444 -TKRAADMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDD 2502
Query: 1234 FETCIHLVGQFDVQLGKSLA----FLYDNRHDDS--------------------IKNLDL 1269
FE + G F +L ++LA + ++ DS +++L L
Sbjct: 2503 FEEVNPVKGSFLKEL-RALAQRKRLIENDTSIDSNSKRRKIAELKLHIKGSTCRVEDLAL 2561
Query: 1270 YF-------MLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFS 1322
F + ++EL++GGS I V NVE+Y+ + + +L G+ Q+ AFR+GF
Sbjct: 2562 NFTVNPPSKVFQYAEMELVDGGSDIDVTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFD 2621
Query: 1323 KSFPYSSLLILTPTELSDLF-GAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNF 1381
+ FP +L +P E+ L G +WS + + GY+ +SP +D++
Sbjct: 2622 RVFPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEAL 2681
Query: 1382 STQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLP 1441
+ Q+++ FLQF TG LP GG NL P+ T+V K G D PSV TC +YLKLP
Sbjct: 2682 TAQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESG----DGSYPSVNTCVHYLKLP 2737
Query: 1442 KYSDKLVLKDRIAQAMTE 1459
+YS +L++R+ A+ E
Sbjct: 2738 EYSSSAILRERLLTAINE 2755
>7297647 [R] KOG4276 Predicted hormone receptor interactor
Length = 2727
Score = 132 bits (333), Expect = 3e-30
Identities = 80/247 (32%), Positives = 131/247 (52%), Gaps = 26/247 (10%)
Query: 999 LPASIYVNPKISAKLSRQLEEPLIVACGVLPSWVLDITRKYGFLFPFETRMNFLQNTSYG 1058
L ++++ KI+ KL +Q+++PL++A LP+W ++ + FLFPFETR + TS+G
Sbjct: 2165 LSEDLFISKKITNKLQQQIQDPLVLASNALPNWCENLNQSCPFLFPFETRQLYFNCTSFG 2224
Query: 1059 YGRLI---QYWREKLADQHH----SNPTENPLHQLGRLTRHKLRVSR-DSLFLSGIKILK 1110
R I Q R+ ++ S ++ ++GRL +++V R + L + ++++K
Sbjct: 2225 ASRSIVCLQSQRDVTVERQRIPIMSPRRDDHEFRIGRLKHERVKVPRNEDLLMWAMQVMK 2284
Query: 1111 KYGSSPNVLEIEYKDEEGTGLGPTLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGA 1170
+ + +VLE+E+ DEEGTGLGPTLEFY+L++ E R L MW + D +D E A
Sbjct: 2285 THCNRKSVLEVEFLDEEGTGLGPTLEFYALVAAEIQRSDLCMWLCDDDLGEDTENSTQSA 2344
Query: 1171 -----------------LFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFN 1213
+FP P L E E LK F G VA+ + D R++D +
Sbjct: 2345 EGNSKPVGYYVNRREHGIFPAP-LPQNSEICENVLKYFWFFGVFVAKVLQDMRLVDIPLS 2403
Query: 1214 AVFFELM 1220
F +L+
Sbjct: 2404 TSFLQLL 2410
Score = 112 bits (279), Expect = 6e-24
Identities = 77/221 (34%), Positives = 110/221 (48%), Gaps = 12/221 (5%)
Query: 1247 QLGKSLAFLYDNRHDDSIKNLDLYFM-LPGYDI------ELLEGGSKILVESFNVEEYLI 1299
+L L N + S+++L L F LP I ELL GS + V N+E Y
Sbjct: 2505 ELINELKLQTQNGLEVSLEDLALTFTYLPSSSIYGYTQAELLPNGSSVNVTIDNLEAYCE 2564
Query: 1300 RVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLF-GAVAEDWSVQTLYSSI 1358
+ + L G+ Q+ AF +GF++ FP L TP+E + G WS + + S
Sbjct: 2565 LLMNFILQDGIAQQMKAFSDGFNEVFPLKKLAAFTPSEARMMICGEQFPHWSREDIISYT 2624
Query: 1359 HADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHP 1418
GY+ DSP +++L + S +++ FLQF TG LP GG NL P+ TVV K
Sbjct: 2625 EPKLGYNKDSPGFQRFVNVLLSMSGDERKAFLQFTTGCSSLPPGGLANLHPRLTVVRKVD 2684
Query: 1419 DGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTE 1459
G S PSV TC +YLKLP Y + ++K+R+ A E
Sbjct: 2685 AGVGS----YPSVNTCVHYLKLPDYPTEEIMKERLLTATKE 2721
>Hs15300020 [R] KOG4276 Predicted hormone receptor interactor
Length = 1592
Score = 132 bits (331), Expect = 5e-30
Identities = 81/246 (32%), Positives = 128/246 (51%), Gaps = 24/246 (9%)
Query: 998 SLPASIYVNPKISAKLSRQLEEPLIVACGVLPSWVLDITRKYGFLFPFETRMNFLQNTSY 1057
+ P + + KI+ K+ +Q+EEPL +A G LP W +T K FL PFETR + T++
Sbjct: 1012 TFPPDEFTSKKITTKILQQIEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAF 1071
Query: 1058 GYGRLIQYWREKLADQHHSNPTENPLHQ-------LGRLTRHKLRVSR-DSLFLSGIKIL 1109
G R I + + + T + + + +GRL +++V R +SL ++
Sbjct: 1072 GASRAIVWLQNRREATVERTRTTSSVRRDDPGEFRVGRLKHERVKVPRGESLMEWAENVM 1131
Query: 1110 KKYGSSPNVLEIEYKDEEGTGLGPTLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYV-- 1167
+ + +VLE+E+ EEGTGLGPTLEFY+L++ EF R L W + + DDE +V
Sbjct: 1132 QIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDL 1191
Query: 1168 -------------TGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNA 1214
+ LF P ++E E+ KLF LG +A+ + DNR++D +
Sbjct: 1192 GGGLKPPGYYVQRSCGLFTAPFPQDSDE-LERITKLFHFLGIFLAKCIQDNRLVDLPISK 1250
Query: 1215 VFFELM 1220
FF+LM
Sbjct: 1251 PFFKLM 1256
Score = 113 bits (283), Expect = 2e-24
Identities = 62/183 (33%), Positives = 98/183 (52%), Gaps = 5/183 (2%)
Query: 1278 IELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTE 1337
++L G ++ N EEY+ +FD + G+ Q+ AFR+GF+K FP L + E
Sbjct: 1408 VDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEE 1467
Query: 1338 LSDLF-GAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGS 1396
+ + G + W+ + + + GY+ DSP + +L S+ +++ FLQF TG
Sbjct: 1468 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 1527
Query: 1397 PKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQA 1456
LP GG NL P+ TVV K + D PSV TC +YLKLP+YS + ++++R+ A
Sbjct: 1528 STLPPGGLANLHPRLTVVRKVD----ATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAA 1583
Query: 1457 MTE 1459
E
Sbjct: 1584 TME 1586
>Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 562
Score = 117 bits (293), Expect = 1e-25
Identities = 102/397 (25%), Positives = 174/397 (43%), Gaps = 65/397 (16%)
Query: 1094 LRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGPTLEFYSLMSKEFARKSLK 1151
L V RDS+F S +++ K + + + + EEG G G E++ ++S E
Sbjct: 208 LLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYA 267
Query: 1152 MWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKT------LKLFENLGTLVARSMLDN 1205
++ ++D GTT + N + L F G ++ ++
Sbjct: 268 LFTQSAD-------------------GTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHR 308
Query: 1206 RILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIK 1265
++++ F F+ K ++ +D V D + K+L ++ DN D S
Sbjct: 309 QLVNIYFTRSFY----KHILGIPVNYQD-------VASIDPEYAKNLQWILDN--DISDL 355
Query: 1266 NLDLYFMLPG------YDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRN 1319
L+L F + ++ L GG ILV N EY+ V + + + + Q+ AF
Sbjct: 356 GLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQ 415
Query: 1320 GFSKSFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLI 1375
GF P S + + EL L + E DW T Y+S GY + P+I
Sbjct: 416 GFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTS-----GYEREDPVIQWFW 470
Query: 1376 DILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK-----PKFTVVLKHPDGNISADHCLPS 1430
+++ + + +++ L LQF+TGS ++P GGF N+ FT+ N+ LP+
Sbjct: 471 EVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNL-----LPT 525
Query: 1431 VMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLLS 1467
TC N LKLP+Y K +LKDR+ A+ GS + ++
Sbjct: 526 SSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA 562
>Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase
Length = 875
Score = 116 bits (291), Expect = 2e-25
Identities = 123/454 (27%), Positives = 194/454 (42%), Gaps = 54/454 (11%)
Query: 1032 VLDITRKYGFLFPFETRMNF------------LQNTSYGYGRLIQYWREKLADQHHSNPT 1079
VL++ + Y F F ET F +N Y I+ + E+ +S
Sbjct: 457 VLEMDKDYTF-FKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQ 515
Query: 1080 ENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNVLEIEYKDEEGTGLGP-TLEFY 1138
L+ RL + + D+L + ++ L +E++ E+G G + EF+
Sbjct: 516 GQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFF 575
Query: 1139 SLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLV 1198
L+ +E + M+ + T L ++ +T F +G ++
Sbjct: 576 QLVVEEIFNPDIGMFTYDESTK----------------LFWFNPSSFETEGQFTLIGIVL 619
Query: 1199 ARSMLDNRILDFRFNAVFF-ELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYD 1257
++ +N ILD F V + +LM K K DL D ++ Q K L
Sbjct: 620 GLAIYNNCILDVHFPMVVYRKLMGK--KGTFRDLGDSHPVLY-------QSLKDLLEYEG 670
Query: 1258 NRHDD-----SIKNLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDM 1312
N DD I DL+ YD++ E G KI + + N +E++ D L K V+
Sbjct: 671 NVEDDMMITFQISQTDLFGNPMMYDLK--ENGDKIPITNENRKEFVNLYSDYILNKSVEK 728
Query: 1313 QLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIIT 1372
Q AFR GF S L L E +L + + Q L + D GY+ DS +I
Sbjct: 729 QFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIR 788
Query: 1373 DLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVM 1432
+ +I+ +F+ +QKRLFLQF TG+ + P+GG L K + PD LP+
Sbjct: 789 EFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKL--KMIIAKNGPD-----TERLPTSH 841
Query: 1433 TCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLL 1466
TC N L LP+YS K LK+R+ +A+T G +L
Sbjct: 842 TCFNVLLLPEYSSKEKLKERLLKAITYAKGFGML 875
>Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase
Length = 872
Score = 116 bits (291), Expect = 2e-25
Identities = 123/454 (27%), Positives = 194/454 (42%), Gaps = 54/454 (11%)
Query: 1032 VLDITRKYGFLFPFETRMNF------------LQNTSYGYGRLIQYWREKLADQHHSNPT 1079
VL++ + Y F F ET F +N Y I+ + E+ +S
Sbjct: 454 VLEMDKDYTF-FKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQ 512
Query: 1080 ENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNVLEIEYKDEEGTGLGP-TLEFY 1138
L+ RL + + D+L + ++ L +E++ E+G G + EF+
Sbjct: 513 GQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFF 572
Query: 1139 SLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLV 1198
L+ +E + M+ + T L ++ +T F +G ++
Sbjct: 573 QLVVEEIFNPDIGMFTYDESTK----------------LFWFNPSSFETEGQFTLIGIVL 616
Query: 1199 ARSMLDNRILDFRFNAVFF-ELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYD 1257
++ +N ILD F V + +LM K K DL D ++ Q K L
Sbjct: 617 GLAIYNNCILDVHFPMVVYRKLMGK--KGTFRDLGDSHPVLY-------QSLKDLLEYEG 667
Query: 1258 NRHDD-----SIKNLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDM 1312
N DD I DL+ YD++ E G KI + + N +E++ D L K V+
Sbjct: 668 NVEDDMMITFQISQTDLFGNPMMYDLK--ENGDKIPITNENRKEFVNLYSDYILNKSVEK 725
Query: 1313 QLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIIT 1372
Q AFR GF S L L E +L + + Q L + D GY+ DS +I
Sbjct: 726 QFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIR 785
Query: 1373 DLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVM 1432
+ +I+ +F+ +QKRLFLQF TG+ + P+GG L K + PD LP+
Sbjct: 786 EFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKL--KMIIAKNGPD-----TERLPTSH 838
Query: 1433 TCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLL 1466
TC N L LP+YS K LK+R+ +A+T G +L
Sbjct: 839 TCFNVLLLPEYSSKEKLKERLLKAITYAKGFGML 872
>Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase
Length = 852
Score = 116 bits (291), Expect = 2e-25
Identities = 123/454 (27%), Positives = 194/454 (42%), Gaps = 54/454 (11%)
Query: 1032 VLDITRKYGFLFPFETRMNF------------LQNTSYGYGRLIQYWREKLADQHHSNPT 1079
VL++ + Y F F ET F +N Y I+ + E+ +S
Sbjct: 434 VLEMDKDYTF-FKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQ 492
Query: 1080 ENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNVLEIEYKDEEGTGLGP-TLEFY 1138
L+ RL + + D+L + ++ L +E++ E+G G + EF+
Sbjct: 493 GQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFF 552
Query: 1139 SLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLV 1198
L+ +E + M+ + T L ++ +T F +G ++
Sbjct: 553 QLVVEEIFNPDIGMFTYDESTK----------------LFWFNPSSFETEGQFTLIGIVL 596
Query: 1199 ARSMLDNRILDFRFNAVFF-ELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYD 1257
++ +N ILD F V + +LM K K DL D ++ Q K L
Sbjct: 597 GLAIYNNCILDVHFPMVVYRKLMGK--KGTFRDLGDSHPVLY-------QSLKDLLEYEG 647
Query: 1258 NRHDD-----SIKNLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDM 1312
N DD I DL+ YD++ E G KI + + N +E++ D L K V+
Sbjct: 648 NVEDDMMITFQISQTDLFGNPMMYDLK--ENGDKIPITNENRKEFVNLYSDYILNKSVEK 705
Query: 1313 QLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIIT 1372
Q AFR GF S L L E +L + + Q L + D GY+ DS +I
Sbjct: 706 QFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIR 765
Query: 1373 DLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVM 1432
+ +I+ +F+ +QKRLFLQF TG+ + P+GG L K + PD LP+
Sbjct: 766 EFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKL--KMIIAKNGPD-----TERLPTSH 818
Query: 1433 TCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLL 1466
TC N L LP+YS K LK+R+ +A+T G +L
Sbjct: 819 TCFNVLLLPEYSSKEKLKERLLKAITYAKGFGML 852
>YGL141w [O] KOG0942 E3 ubiquitin protein ligase
Length = 910
Score = 111 bits (277), Expect = 1e-23
Identities = 120/442 (27%), Positives = 198/442 (44%), Gaps = 50/442 (11%)
Query: 1033 LDITRKYGFLFPFETRMNFLQNTSYGYGRLIQYWREKLADQHHSNPTENPLHQLGRLTRH 1092
L+I + F PFE R++ Y + L + R L D H+ P G + +
Sbjct: 501 LEILLELPFFIPFEERVDLF----YMFIALDKK-RLSLDDDHNLINMFTPWASTG-MRKQ 554
Query: 1093 KLRVSRDSL----FLSGIKILKKYGSSPNVLEI-EYKDEEGT-GLGPTLEFYSLMSKE-F 1145
+SRD++ F + I +++ +S +V I E+ +E G G G T EF + +S E F
Sbjct: 555 SAIISRDNVLEDAFNAFNSIGERFKASLDVTFINEFGEEAGIDGGGITKEFLTTVSDEGF 614
Query: 1146 ARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDN 1205
++++TN D E L+P + T+ LK LG +V + + ++
Sbjct: 615 KDPKHELFRTN-----DRYE-----LYPSVVYDATK------LKYIWFLGKVVGKCLYEH 658
Query: 1206 RILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIK 1265
++D F F + + D +G +D L +L L N D IK
Sbjct: 659 VLIDVSFADFFLKKLLNYSNGFLSSFSD-------LGSYDSVLYNNLIKLL-NMTTDEIK 710
Query: 1266 NLDLYFMLPGYD-----IELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNG 1320
+LDL F + + ++L+ GSK V NV Y+ +V D L K ++AF G
Sbjct: 711 SLDLTFEIDEPESSAKVVDLIPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGG 770
Query: 1321 FSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSN 1380
S + + EL L ++ + L S+ GY + I D ++L+
Sbjct: 771 LSVIIAPHWMEMFNSIELQMLISGERDNIDLDDLKSNTEYG-GYKEEDQTIVDFWEVLNE 829
Query: 1381 FSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISAD-HCLPSVMTCANYLK 1439
F ++K FL+F+T P+ PL GFK L PKF + N + + LP+ TC N LK
Sbjct: 830 FKFEEKLNFLKFVTSVPQAPLQGFKALDPKFGI------RNAGTEKYRLPTASTCVNLLK 883
Query: 1440 LPKYSDKLVLKDRIAQAMTEGS 1461
LP Y +K +L++++ A+ G+
Sbjct: 884 LPDYRNKTILREKLLYAINSGA 905
>At3g17205 [O] KOG0942 E3 ubiquitin protein ligase
Length = 873
Score = 107 bits (267), Expect = 1e-22
Identities = 84/298 (28%), Positives = 140/298 (46%), Gaps = 22/298 (7%)
Query: 1171 LFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLD 1230
L+P P G E + L+ F LG+L+A++M + ++D F A FF K N D
Sbjct: 588 LYPNPGSGMIHEQH---LQFFHFLGSLLAKAMFEGILVDIPF-ATFFLSKLKQKYNYLND 643
Query: 1231 LEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDI------ELLEGG 1284
L D +L + L FL R+ I +L+LYF++ + ELL GG
Sbjct: 644 LPSL----------DPELYRHLIFL--KRYKGDISDLELYFVILNNEYGERTEEELLPGG 691
Query: 1285 SKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGA 1344
+ V + NV ++ V + L + Q + F GF + P + + EL L
Sbjct: 692 QDMRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIPKEWIDMFNEHELQVLISG 751
Query: 1345 VAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGF 1404
+ + L ++ + GY +I +++ +FST+ ++ FL+F+TG + PL GF
Sbjct: 752 SVDSLDIDDLRNNTNYAGGYHAGHYVIDMFWEVMKSFSTENQKKFLKFVTGCSRGPLLGF 811
Query: 1405 KNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
K L+P F + + + LP+ TC N LKLP Y K +L+ ++ A++ +G
Sbjct: 812 KYLEPAFCIQRAAGSASNESVDRLPTSATCMNLLKLPPYQSKELLETKLMYAISAEAG 869
>At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3891
Score = 103 bits (258), Expect = 2e-21
Identities = 98/361 (27%), Positives = 153/361 (42%), Gaps = 45/361 (12%)
Query: 1119 LEIEYKDEEGTGLGP-TLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLL 1177
L ++++ EEG G T E+Y L+S+ K ++ T + + + P P
Sbjct: 3558 LNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDATFQ---------PNPNS 3608
Query: 1178 GTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETC 1237
E+ L F+ +G +VA+++ D ++LD F F++ + +
Sbjct: 3609 VYQTEH----LSYFKFVGRMVAKALFDGQLLDVYFTRSFYK-----------HILGVKVT 3653
Query: 1238 IHLVGQFDVQLGKSLAFLYDNRHDDSIK---NLD-------LYFMLPGYDIELLEGGSKI 1287
H + D K+L +L +N D + ++D LY D EL GG I
Sbjct: 3654 YHDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNI 3713
Query: 1288 LVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE 1347
V EY+ V L + Q+ AF GF++ P + I EL L + E
Sbjct: 3714 RVTEETKHEYVDLVAGHILTNAIRPQINAFLEGFNELIPRELVSIFNDKELELLISGLPE 3773
Query: 1348 ----DWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGG 1403
D T Y+S Y+ SP+I +++ FS + FLQF+TG+ K+PL G
Sbjct: 3774 IDFDDLKANTEYTS------YTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEG 3827
Query: 1404 FKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGA 1463
FK L+ A LPS TC N L LP+Y K L++R+ A+ E S
Sbjct: 3828 FKALQGISGPQRLQIHKAYGAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEG 3887
Query: 1464 F 1464
F
Sbjct: 3888 F 3888
>At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3658
Score = 102 bits (253), Expect = 6e-21
Identities = 95/361 (26%), Positives = 154/361 (42%), Gaps = 45/361 (12%)
Query: 1119 LEIEYKDEEGTGLGP-TLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLL 1177
L ++++ EEG G T E+Y L+S+ K ++ T + + + P P
Sbjct: 3325 LNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDATFQ---------PNPNS 3375
Query: 1178 GTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETC 1237
E+ L F+ +G +VA+++ D ++LD F F++ + +
Sbjct: 3376 VYQTEH----LSYFKFVGRMVAKALFDGQLLDVYFTRSFYK-----------HILGVKVT 3420
Query: 1238 IHLVGQFDVQLGKSLAFLYDNRHDDSIK---NLD-------LYFMLPGYDIELLEGGSKI 1287
H + D K+L +L +N D + ++D LY D EL GG I
Sbjct: 3421 YHDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNI 3480
Query: 1288 LVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE 1347
V EY+ V D L + Q+ AF G ++ P + I EL L + E
Sbjct: 3481 RVTEETKHEYVDLVADHILTSAIRPQINAFLEGLNELIPRELVSIFNDKELELLISGLPE 3540
Query: 1348 ----DWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGG 1403
D T Y+S Y++ SP+I +++ FS + FLQF+TG+ K+PL G
Sbjct: 3541 IDFDDLKANTEYTS------YTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEG 3594
Query: 1404 FKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGA 1463
FK L+ + LPS TC N L LP+Y K +++R+ A+ E +
Sbjct: 3595 FKALQGISGPQRLQIHKAYGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEG 3654
Query: 1464 F 1464
F
Sbjct: 3655 F 3655
>SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3227
Score = 101 bits (251), Expect = 1e-20
Identities = 99/389 (25%), Positives = 166/389 (42%), Gaps = 54/389 (13%)
Query: 1094 LRVSRDSLFLSGIKILKKYGSSP---NVLEIEYKDEEGTGLGP-TLEFYSLMSKEFARKS 1149
+ V RD +FL + L + + L I ++DEEG G T E+ +++++
Sbjct: 2872 ITVRRDHVFLDSYRALHFKDADEVKFSKLNIHFRDEEGVDAGGVTREWLQVLARQMFNPD 2931
Query: 1150 LKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKT------LKLFENLGTLVARSML 1203
++ VTG TT N + L F+ G ++ +++
Sbjct: 2932 YALFLP-----------VTGD-------ATTFHPNRDSSVNPDHLSFFKFTGRIIGKALY 2973
Query: 1204 DNRILDFRFN-AVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDD 1262
D R+LD F+ AV+ ++H+ + ++D E+ D KSL ++ +N D
Sbjct: 2974 DGRLLDCHFSRAVYKHMLHRS-----VSVKDIES-------LDPDYYKSLVWMLNNDITD 3021
Query: 1263 SIKN---LDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRN 1319
I ++ ++L+ G I V N + Y+ R+ D L + V QL + +
Sbjct: 3022 IITEEFAVEKDVFGEKTVVDLIPNGRNIPVTELNKQNYVNRMVDYKLRESVKDQLKSLLD 3081
Query: 1320 GFSKSFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLI 1375
GFS P + I EL L + E DW T Y HGY++ SP +
Sbjct: 3082 GFSDIIPSHLIQIFNEQELELLISGLPEIDIDDWKNNTEY------HGYNVSSPQVQWFW 3135
Query: 1376 DILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCA 1435
+ +F +++ LQF TG+ K+PL GFK L+ + + + + LP TC
Sbjct: 3136 RAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSYGSLNRLPQSHTCF 3195
Query: 1436 NYLKLPKYSDKLVLKDRIAQAMTEGSGAF 1464
N L LP+Y L+ + A+ EGS F
Sbjct: 3196 NQLDLPEYDTYEQLRSMLLTAINEGSEGF 3224
>SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase
Length = 1029
Score = 99.8 bits (247), Expect = 3e-20
Identities = 107/444 (24%), Positives = 187/444 (42%), Gaps = 48/444 (10%)
Query: 1033 LDITRKYGFLFPFETRMNFLQNTSY--GYGRLIQYWREKLADQHHSNPTENPLHQLGRLT 1090
++IT K+ R+N L N S+ + I ++ L +N P L
Sbjct: 616 INITYKFDNFSESRPRLNILNNCSFFLPFHFRIHLLQQLLLLDKQANGYAQPFGHL---- 671
Query: 1091 RHKLRVSRDSLFLSGIKILKKYGSS-PNVLEIEYKDEEGT------GLGPTLEFYSLMSK 1143
+H + + R+ +F G +G + I + DE G G G T EF + + K
Sbjct: 672 KHAV-IRRNRIFDDGFDAFYNFGKLLKGPIRITFVDEHGVVEEGIDGGGLTKEFLTSICK 730
Query: 1144 EFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSML 1203
++ N + + ++ L+P + + L+ +E LG L+ + +
Sbjct: 731 T-------VFDINYGLFSETKAHL---LYPNT---HAYAQDVERLRCYEFLGMLIGKCIY 777
Query: 1204 DNRILDFRFNAVFFE--LMHKCCKNDRLDLED--FETCIHLVGQFDVQLGKSLAFLYDNR 1259
+ +D F + F L H +D L+ +E + L +D + +A +
Sbjct: 778 EGIQIDAAFASFFVAKWLGHPSYFDDLTSLDPNLYEGLVFLKN-YDGDVENDMALNFTVV 836
Query: 1260 HDD-SIKNLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFR 1318
H++ ++N+ I+L+ GS I V + N +Y+ V + +L + Q AF
Sbjct: 837 HEEFGVRNV----------IDLIPNGSNISVTNENRLQYIHLVSNYYLNARLSRQCRAFT 886
Query: 1319 NGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDIL 1378
NGF++ L + +E+ L G + L GY +SP I ++L
Sbjct: 887 NGFTQIIDPHWLAMFHESEIQILVGGDPVPIDIDDLRRHTVYAGGYEPNSPTIVLFWEVL 946
Query: 1379 SNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYL 1438
F + KR F++F+T + P+ GFK L P F + + D + LP+ TC N L
Sbjct: 947 REFEEEDKRSFVKFVTSVARPPILGFKALMPSFCIRVNGED-----ETRLPTASTCVNLL 1001
Query: 1439 KLPKYSDKLVLKDRIAQAMTEGSG 1462
KLP YS K L+D++ A+ G G
Sbjct: 1002 KLPMYSTKQTLRDKLLTAVRSGVG 1025
>Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1083
Score = 99.0 bits (245), Expect = 5e-20
Identities = 89/345 (25%), Positives = 149/345 (42%), Gaps = 35/345 (10%)
Query: 1125 DEEGT-GLGPTLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEEN 1183
DE G G G EF + + K + +KT ++ G L+P P
Sbjct: 763 DEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNE----------GLLYPNPAAQMLV-- 810
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQ 1243
+ + + L ++ +++ +N +++ F F +L + IH +
Sbjct: 811 GDSFARHYYFLARMLGKALYENMLVELPFAGFFLS---------KLLGTSADVDIHHLAS 861
Query: 1244 FDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYD------IELLEGGSKILVESFNVEEY 1297
D ++ K+L FL ++D ++ L L F + D +EL GG I V S N Y
Sbjct: 862 LDPEVYKNLLFL--KSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTSANRIAY 919
Query: 1298 LIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSS 1357
+ V D L + + AFR G + L + E+ L S++ L S
Sbjct: 920 IHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSF 979
Query: 1358 IHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKH 1417
+ GYS D P+I ++ F+ ++KR L+F+T + PL GFK L P F + H
Sbjct: 980 TNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCI---H 1036
Query: 1418 PDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
G S LP+ TC N LKLP++ D+ +L+ ++ A+ +G
Sbjct: 1037 NGG--SDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAG 1079
>CE19147 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1066
Score = 97.1 bits (240), Expect = 2e-19
Identities = 98/406 (24%), Positives = 178/406 (43%), Gaps = 65/406 (16%)
Query: 1094 LRVSRDSLFLSGIKILKKYG--SSPNVLEIEYKDEEG---TGL---GPTLEFYSLMSKEF 1145
+ V R+ + G L K + + + +++ +E+G G+ G EF L K+
Sbjct: 685 ITVQRNRIIEDGFNHLSKLTIPALKSTIRVKFVNEQGLDEAGIDQDGVFKEFLELTLKKV 744
Query: 1146 ARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDN 1205
L ++ T S TG L+P P T ++ L LF +G ++ +++ +
Sbjct: 745 FDPQLNLFSTTS----------TGVLYPSP----TSSLHDDHLALFTFVGRMLGKAVYEG 790
Query: 1206 RILDFRFNAVFFELM---HKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDD 1262
++D + V + H+ C D L Q D +L +SL F+ R++
Sbjct: 791 IVVDVQLAPVLLAAVLGSHRLCAFDELS------------QLDPELYRSLTFV--KRYEG 836
Query: 1263 SIKNLDLYFMLPG------YDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAA 1316
+ +L L F + ++L+ G I V + N +Y+ R+ + + Q A
Sbjct: 837 EMADLSLTFSVDEDFMGKISTVDLVPSGRTISVTNENKIDYVHRMAHHRVFRRTQEQCKA 896
Query: 1317 FRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLID 1376
F G + L + P +L L V D + L ++ G+ + +I L D
Sbjct: 897 FVTGMQSILQPTWLSLFAPNDLQCLISGVNSDIDLADLKRNVQYFGGFHGNHRLIKWLWD 956
Query: 1377 ILSN-FSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTV----VLKHPD-----GNI---- 1422
IL N F++++++LFL+F+T + P+ GF L+P F++ V D G++
Sbjct: 957 ILENKFTSEERKLFLKFVTSCSRPPVLGFSYLEPPFSIRCVEVSDDQDQGDTLGSVVRGF 1016
Query: 1423 ------SADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
+A LP+ TC N LKLP Y+ K +L +++ A+ G+G
Sbjct: 1017 LALRKGTAATRLPTASTCFNLLKLPNYNKKSLLLEKLRYAIHAGTG 1062
>CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 817
Score = 94.4 bits (233), Expect = 1e-18
Identities = 109/411 (26%), Positives = 179/411 (43%), Gaps = 76/411 (18%)
Query: 1093 KLRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGPTL-EFYSLMSKEFARKS 1149
K+ VSR+++F + + + + L I+++ EEG G E++ L+S E
Sbjct: 440 KITVSRNNVFEDSFQEIMRKNAVDLRRRLYIQFRGEEGLDYGGVAREWFFLLSHEVLNPM 499
Query: 1150 --LKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRI 1207
L M+ N++ S + A F P LK FE +G +A
Sbjct: 500 YCLFMYAGNNNYSLQ----INPASFVNP----------DHLKYFEYIGRFIAMLKKPGNF 545
Query: 1208 LDFRF----------NAVF--------FEL-MHKCCKNDRLDLEDFETCIHLVGQFDVQL 1248
D +F NA+F F + +K N ++ L+D E Q D ++
Sbjct: 546 DDLKFSDQYISFSPKNALFHGKFIYSGFTMPFYKKMLNKKIVLKDIE-------QVDSEI 598
Query: 1249 GKSLAFLYDNRHDDSIKNLDLYFMLPGYDI-------ELLEGGSKILVESFNVEEYLIRV 1301
SL ++ DN D+ +++LYF+ Y++ EL EGG++I V N EY+ +
Sbjct: 599 YNSLMWIKDNNIDEC--DMELYFVAD-YELLGELKTYELKEGGTEIAVTEENKLEYIELL 655
Query: 1302 FDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAV----AEDWSVQTLYSS 1357
+ +GV+ Q AF GF+ FP + EL L + +DW T+Y
Sbjct: 656 VEWRFNRGVEQQTKAFFTGFNSVFPLEWMQYFDERELELLLCGMQDVDVDDWQRNTVY-- 713
Query: 1358 IHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK----PKFTV 1413
Y+ S +T + + +++ LQF+TG+ ++P+GGF L P+
Sbjct: 714 ----RHYAPQSKQVTWFWQWVRSLDQEKRARLLQFVTGTCRVPVGGFSELMGSTGPQLFC 769
Query: 1414 VLKHPDGNISADHCLPSVMTCANYLKLPKYS--DKLVLKDRIAQAMTEGSG 1462
+ + + ++ LP TC N L LP Y D+LV K +A MTEG G
Sbjct: 770 IER-----VGKENWLPRSHTCFNRLDLPPYRSYDQLVEKLSMAIEMTEGFG 815
>SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 767
Score = 94.0 bits (232), Expect = 2e-18
Identities = 81/294 (27%), Positives = 133/294 (44%), Gaps = 41/294 (13%)
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQ 1243
N + L F+ +G ++ ++ R +D F F++++ + ++ L+D E+
Sbjct: 496 NPEHLNYFKFIGRVIGLAIFHRRFVDAFFVVSFYKMILQ----KKVTLQDMES------- 544
Query: 1244 FDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKILVESFNVEEY 1297
D + +SL ++ DN D LDL F + I+L G I V N EY
Sbjct: 545 MDAEYYRSLVWILDN---DITGVLDLTFSVEDNCFGEVVTIDLKPNGRNIEVTEENKREY 601
Query: 1298 LIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DWSVQT 1353
+ V + K ++ Q AF GFS+ P + + EL L G ++E DW T
Sbjct: 602 VDLVTVWRIQKRIEEQFNAFHEGFSELIPQELINVFDERELELLIGGISEIDMEDWKKHT 661
Query: 1354 LYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK----- 1408
Y S YS + II +++ +S ++K LQF TG+ ++P+ GFK+L+
Sbjct: 662 DYRS------YSENDQIIKWFWELMDEWSNEKKSRLLQFTTGTSRIPVNGFKDLQGSDGP 715
Query: 1409 PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
KFT+ + LP TC N L LP Y+ K L +++ A+ E G
Sbjct: 716 RKFTI------EKAGEPNKLPKAHTCFNRLDLPPYTSKKDLDHKLSIAVEETIG 763
>ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 2410
Score = 92.8 bits (229), Expect = 4e-18
Identities = 88/362 (24%), Positives = 157/362 (43%), Gaps = 53/362 (14%)
Query: 1119 LEIEYKDEEGTGLGP-TLEFYSLMSKEFARKSLKMWKTNSDTSDD----EEEYVTGALFP 1173
LEI+ EEG G T E+ L++K+ + +++ ++ + YV
Sbjct: 2083 LEIKLTGEEGLDYGGLTREWLVLLAKDLLDPNFALFEFATEDKTTVVPCKNSYV------ 2136
Query: 1174 GPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFE-LMHKCCKNDRLDLE 1232
N + L F+ +G ++A++++D ++ + ++ ++ K C DL+
Sbjct: 2137 ----------NPEHLSYFKFVGRIIAKAIMDGNFINLHLSKFIYQYILGKSC-----DLQ 2181
Query: 1233 DFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYD------IELLEGGSK 1286
D E+ D + KSL ++ DN D K+L + F +EL+EGG+
Sbjct: 2182 DLESA-------DPEFHKSLVWIRDNPVD---KSLGITFSFDDVSFGVHRTVELVEGGAH 2231
Query: 1287 ILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAV- 1345
+ V+ N EY+ L G+++QL+A ++G + +L + +EL L +
Sbjct: 2232 VFVDDSNKAEYVKLATQYRLFNGIELQLSALKSGLFEILGSKALEMFDESELELLICGIP 2291
Query: 1346 ---AEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLG 1402
+DW TLY +GY+ +S + + + + + LQF+TG+ LP
Sbjct: 2292 DIDVDDWKNNTLY------YGYAENSKTVIWFWRAVKSLDSVSRAKLLQFVTGTSTLPFE 2345
Query: 1403 GFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
GF +L+ V LP+ TC N L LP+YS L + A+ E S
Sbjct: 2346 GFSHLQGNNEVQKFSIHKVSDRIDSLPTAHTCFNQLVLPEYSSYENLLKYLTLAINECST 2405
Query: 1463 AF 1464
F
Sbjct: 2406 GF 2407
>7295004 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1078
Score = 92.4 bits (228), Expect = 5e-18
Identities = 87/351 (24%), Positives = 153/351 (42%), Gaps = 44/351 (12%)
Query: 1136 EFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLG 1195
EF K+ SL ++KT SD L+P P+ ++N+ L+LFE +G
Sbjct: 744 EFLEETIKKVFDPSLNLFKTTSDQR----------LYPSPI-SYVQDNH---LELFEFVG 789
Query: 1196 TLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFL 1255
++ +++ + ++D F + F + + + +C+ + D +L +SL F+
Sbjct: 790 RMLGKAVYEGIVVDVPFASFFLSQLLGQTQ------QALYSCMDELPSLDNELYRSLTFI 843
Query: 1256 YDNRHDDSIKNL----DLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVD 1311
+ D S NL D M + L GG +V N Y+ + + +
Sbjct: 844 KHYKQDVSDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIR 903
Query: 1312 MQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPII 1371
Q AF GF L + +P EL L ++ L H G+ ++
Sbjct: 904 EQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQVV 963
Query: 1372 TDLIDILS-NFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTV-VLKHPDGNISAD---- 1425
L DIL+ +F+ ++++LFL+F+T K PL GF +L+P F++ ++ D + D
Sbjct: 964 CWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGS 1023
Query: 1426 --------------HCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
+ LP+ TC N LKLP Y K L+D++ A++ +G
Sbjct: 1024 VIRGFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTG 1074
>7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1082
Score = 92.4 bits (228), Expect = 5e-18
Identities = 106/410 (25%), Positives = 176/410 (42%), Gaps = 64/410 (15%)
Query: 1074 HHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNV---LEIEYKDEEGTG 1130
H PT P + ++R+ R S+ +I+ + + L +E++ E G
Sbjct: 714 HIRKPTNVP-------NKFEIRIRRTSILEDSYRIISSVTKTDLLKTKLWVEFEGETGLD 766
Query: 1131 LGPTL-EFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLK 1189
G E++ L+SKE ++ EY + + + NE+ L
Sbjct: 767 YGGLAREWFYLLSKEMFNPYYGLF-----------EYSAMDNYTLQINNGSGLCNEEHLS 815
Query: 1190 LFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLG 1249
F+ +G + ++ ++LD F F+++M + +DL+D E+ D +
Sbjct: 816 YFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQ----KPIDLKDMESV-------DTEYY 864
Query: 1250 KSLAFLYDNRHDDSIKNLDLYFMLPGYDI-------ELLEGGSKILVESFNVEEYLIRVF 1302
SL ++ +N D I L+L F L D+ EL GG+ I V + N +EY+ V
Sbjct: 865 NSLMWIKEN--DPRI--LELTFCLDE-DVFGQKSQHELKPGGANIDVTNENKDEYIKLVI 919
Query: 1303 DQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAV----AEDWSVQTLYSSI 1358
+ V Q+++F +GF P + + I EL L + +DW TLY
Sbjct: 920 EWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELLMCGIQNIDVKDWRENTLYKG- 978
Query: 1359 HADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL----KPKFTVV 1414
Y M+ II + +FS + + LQF+TG+ ++P+ GFK L P+ +
Sbjct: 979 ----DYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQMFTI 1034
Query: 1415 LKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAF 1464
K N P TC N L LP Y L LKD++ +A+ EGS F
Sbjct: 1035 EKWGTPN-----NFPRAHTCFNRLDLPPYEGYLQLKDKLIKAI-EGSQGF 1078
>7291760 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1122
Score = 92.4 bits (228), Expect = 5e-18
Identities = 82/298 (27%), Positives = 130/298 (43%), Gaps = 26/298 (8%)
Query: 1171 LFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLD 1230
L+P P + E+ EK + +G ++ +S+ +N +++ A FF L K +D
Sbjct: 841 LYPNPNVADLFEDYEKH---YYFIGRILGKSIYENLLVELPL-AEFF-LTKLAGKYSDVD 895
Query: 1231 LEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYD----IELLEGGSK 1286
IH + D +L ++L +L D D S NLD +EL G
Sbjct: 896 -------IHQLASLDPELYRNLLYLKDYSGDVSELNLDFTVASSSLGQTQIVELKPQGQS 948
Query: 1287 ILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVA 1346
I V + N EYL + D L + AFR G S P L + + EL L
Sbjct: 949 IPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAE 1008
Query: 1347 EDWSVQTLYSSIHADHG--YSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGF 1404
++ L H ++G +S + P I ++L F Q+R L+F+T + PL GF
Sbjct: 1009 IPIDLEDLKK--HCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGF 1066
Query: 1405 KNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
K+L P F + N LP+ TC N LKLP + +++++ A+ G+G
Sbjct: 1067 KDLDPPFFI------QNTGDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAG 1118
>SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 671
Score = 92.0 bits (227), Expect = 6e-18
Identities = 98/386 (25%), Positives = 163/386 (41%), Gaps = 52/386 (13%)
Query: 1093 KLRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGP-TLEFYSLMSKEFARKS 1149
+L+VSR + F I+ K S L I +++E+G G + EF+ ++S
Sbjct: 318 QLKVSRATTFEDAYDIISKLSVSDMKKKLLIRFRNEDGLDYGGVSREFFYILSHAIFNPG 377
Query: 1150 LKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILD 1209
++ EY T + G + N F +G ++ ++ R LD
Sbjct: 378 YSLF-----------EYATDDNY-GLQISPLSSVNPDFRSYFRFVGRVMGLAIYHRRYLD 425
Query: 1210 FRFNAVFFE--LMHKCCKNDRLDLED-FETCIHLVGQFDVQLGKSLAF-LYDNRHDDSIK 1265
+F F++ L C D D+++ + + + DV L F + +NR +S+
Sbjct: 426 VQFVLPFYKRILQKPLCLEDVKDVDEVYYESLKWIKNNDVDESLCLNFSVEENRFGESVT 485
Query: 1266 NLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSF 1325
++L+ G I V + N YL + + L + Q A + G ++
Sbjct: 486 ------------VDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQFNALKGGLNELI 533
Query: 1326 PYSSLLILTPTELSDLFGAV----AEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNF 1381
P S L I EL L +DW T Y S Y+ I+ ++LS +
Sbjct: 534 PDSVLQIFNENELDTLLNGKRDIDVQDWKRFTDYRS------YTETDDIVIWFWELLSEW 587
Query: 1382 STQQKRLFLQFITGSPKLPLGGFKNL-----KPKFTVVLKHPDGNISADHCLPSVMTCAN 1436
S ++K LQF TG+ +LPL GFK++ KFT+ G+IS LP TC N
Sbjct: 588 SPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTI---EKVGHISQ---LPKAHTCFN 641
Query: 1437 YLKLPKYSDKLVLKDRIAQAMTEGSG 1462
L +P Y+ K L+ ++ A+ E +G
Sbjct: 642 RLDIPPYNSKEELEQKLTIAIQETAG 667
>YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3268
Score = 91.7 bits (226), Expect = 8e-18
Identities = 97/389 (24%), Positives = 159/389 (39%), Gaps = 48/389 (12%)
Query: 1094 LRVSRDSLFLSGIKIL--KKYGSSPNV-LEIEYKDEEGTGLGP-TLEFYSLMSKEFARKS 1149
+ V R+ +FL + L K N LEI +K E G G T E+Y ++S++
Sbjct: 2913 ITVRREQVFLDSYRALFFKTNDEIKNSKLEITFKGESGVDAGGVTREWYQVLSRQMFNPD 2972
Query: 1150 LKMW-KTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRIL 1208
++ SD + +G N + L F+ +G ++ +++ D L
Sbjct: 2973 YALFLPVPSDKTTFHPNRTSGI-------------NPEHLSFFKFIGMIIGKAIRDQCFL 3019
Query: 1209 DFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLD 1268
D F+ ++K + L+D E+ D KSL ++ +N D I+
Sbjct: 3020 DCHFSRE----VYKNILGRPVSLKDMES-------LDPDYYKSLVWILENDITDIIEET- 3067
Query: 1269 LYFMLPGYD------IELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFS 1322
F + D I L+EGG I+V N ++Y+ +V + L V Q+ F GF
Sbjct: 3068 --FSVETDDYGEHKVINLIEGGKDIIVTEANKQDYVKKVVEYKLQTSVKEQMDNFLVGFY 3125
Query: 1323 KSFPYSSLLILTPTELSDLFGAV----AEDWSVQTLYSSIHADHGYSMDSPIITDLIDIL 1378
+ I EL L + +DW T Y + Y+ ++ +
Sbjct: 3126 ALISKDLITIFDEQELELLISGLPDIDVDDWKNNTTYVN------YTATCKEVSYFWRAV 3179
Query: 1379 SNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYL 1438
+F +++ LQF+TG+ K+PL GFK L V + + LPS TC N L
Sbjct: 3180 RSFDAEERAKLLQFVTGTSKVPLNGFKELSGVNGVCKFSIHRDFGSSERLPSSHTCFNQL 3239
Query: 1439 KLPKYSDKLVLKDRIAQAMTEGSGAFLLS 1467
LP Y L+ + A+ EG F L+
Sbjct: 3240 NLPPYESYETLRGSLLLAINEGHEGFGLA 3268
>Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 91.7 bits (226), Expect = 8e-18
Identities = 79/297 (26%), Positives = 130/297 (43%), Gaps = 46/297 (15%)
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQ 1243
N L F +G +A ++ + +D F F++ M N R L+D E+
Sbjct: 598 NPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRM----LNKRPTLKDLES------- 646
Query: 1244 FDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDIELL---------EGGSKILVESFNV 1294
D + S+ ++ +N ++ L+LYF+ D+E+L EGG I V N
Sbjct: 647 IDPEFYNSIVWIKENNLEEC--GLELYFI---QDMEILGKVTTHELKEGGESIRVTEENK 701
Query: 1295 EEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DWS 1350
EEY++ + D +GV+ Q AF +GF++ P L EL + + E DW
Sbjct: 702 EEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQ 761
Query: 1351 VQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL--- 1407
T+Y Y+ +S I ++ +++ LQF+TG+ +LP+GGF L
Sbjct: 762 KSTIY------RHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGS 815
Query: 1408 --KPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
KF + + + LP TC N L LP Y L++++ A+ E G
Sbjct: 816 NGPQKFCI------DKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEG 866
>Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 91.7 bits (226), Expect = 8e-18
Identities = 79/297 (26%), Positives = 130/297 (43%), Gaps = 46/297 (15%)
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQ 1243
N L F +G +A ++ + +D F F++ M N R L+D E+
Sbjct: 598 NPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRM----LNKRPTLKDLES------- 646
Query: 1244 FDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDIELL---------EGGSKILVESFNV 1294
D + S+ ++ +N ++ L+LYF+ D+E+L EGG I V N
Sbjct: 647 IDPEFYNSIVWIKENNLEEC--GLELYFI---QDMEILGKVTTHELKEGGESIRVTEENK 701
Query: 1295 EEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DWS 1350
EEY++ + D +GV+ Q AF +GF++ P L EL + + E DW
Sbjct: 702 EEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQ 761
Query: 1351 VQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL--- 1407
T+Y Y+ +S I ++ +++ LQF+TG+ +LP+GGF L
Sbjct: 762 KSTIY------RHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGS 815
Query: 1408 --KPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
KF + + + LP TC N L LP Y L++++ A+ E G
Sbjct: 816 NGPQKFCI------DKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEG 866
>CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 875
Score = 91.7 bits (226), Expect = 8e-18
Identities = 108/418 (25%), Positives = 176/418 (41%), Gaps = 60/418 (14%)
Query: 1064 QYWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSP--NVLEI 1121
+Y+R++L S P R ++VSR+ +F + L + S N I
Sbjct: 497 KYFRKELTKLEPSMPRY-------RRNDVSVQVSRNRVFSDSFRELFRLRPSEWKNRFYI 549
Query: 1122 EYKDEEGTGLGPTL-EFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTT 1180
++ EEG G L E++S++++E + ++ T D Y ++
Sbjct: 550 IFQGEEGQDAGGLLREWFSVITREIFNPNYALFIT---APGDMVTY---------MINKA 597
Query: 1181 EENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHL 1240
N + L F+ +G L+A+S+ +++ LD F F+ K N + +D E+
Sbjct: 598 SYINPEHLDYFKFVGRLIAKSVFEHKYLDCYFTRAFY----KHILNLPVRYQDLES---- 649
Query: 1241 VGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDI----ELLEGGSKILVESFNVEE 1296
D KSL FL N DD +L + + + +L G KI V N +E
Sbjct: 650 ---EDPAFFKSLDFLLQNPIDDLALDLTFSTEVEEFGVRSVRDLKPNGRKIEVNDANKDE 706
Query: 1297 YLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVA----EDWSVQ 1352
Y+ V + + QL AF GF + P + + EL L + +D +
Sbjct: 707 YVKLVCQMKMTGSIRKQLDAFLTGFYEIIPKDLISMFNEQELELLISGLPTVDIDDMAAN 766
Query: 1353 TLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK---- 1408
T Y G+ S I L +F + K FLQF+TG+ K+PL GF +L+
Sbjct: 767 TDYK------GFQKTSTHIQWFWRALRSFEKEDKAKFLQFVTGTSKVPLQGFASLEGMNG 820
Query: 1409 -PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAM---TEGSG 1462
KF++ + G+ LP+ TC N L LP+Y L+ + A+ TEG G
Sbjct: 821 VQKFSIHMDSRGGD-----RLPAAHTCFNQLDLPQYESYEKLRQSLLLAIRECTEGFG 873
>Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 922
Score = 90.5 bits (223), Expect = 2e-17
Identities = 102/402 (25%), Positives = 166/402 (40%), Gaps = 62/402 (15%)
Query: 1083 LHQLGRLTRH-KLRVSRDSLF---LSGIKILKKYGSSPNVLEIEYKDEEGTGLGPTL-EF 1137
L Q L H K+ VSR +LF I LK Y + I ++ EEG G E+
Sbjct: 557 LCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVI-FRGEEGLDYGGLAREW 615
Query: 1138 YSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTL 1197
+ L+S E +++ + + + N L F +G
Sbjct: 616 FFLLSHEVLNPMYCLFEYAGKNNYCLQ------------INPASTINPDHLSYFCFIGRF 663
Query: 1198 VARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYD 1257
+A ++ + +D F+ F++ M + +L ++D E+ D + SL ++ D
Sbjct: 664 IAMALFHGKFIDTGFSLPFYKRM----LSKKLTIKDLES-------IDTEFYNSLIWIRD 712
Query: 1258 NRHDDSIKNLDLYFMLP--------GYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKG 1309
N ++ L++YF + +D++L GGS ILV N +EY+ + + +G
Sbjct: 713 NNIEEC--GLEMYFSVDMEILGKVTSHDLKL--GGSNILVTEENKDEYIGLMTEWRFSRG 768
Query: 1310 VDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYS 1365
V Q AF +GF++ P L EL + + E DW T+Y Y+
Sbjct: 769 VQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVY------RHYT 822
Query: 1366 MDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL-----KPKFTVVLKHPDG 1420
+S I + + + LQF+TG+ +LPLGGF L KF +
Sbjct: 823 RNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCI------E 876
Query: 1421 NISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
+ D LP TC N L LP Y LK+++ A+ E G
Sbjct: 877 KVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEG 918
>CE15744 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1001
Score = 89.7 bits (221), Expect = 3e-17
Identities = 79/309 (25%), Positives = 143/309 (45%), Gaps = 42/309 (13%)
Query: 1171 LFPGP----LLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKN 1226
L+P P LLG L F+ +G ++ + + + ++ + RF F + + KN
Sbjct: 714 LYPNPTAPFLLGVD------CLAHFQFIGRMIGKLIYERQLQEVRFAEFFIAQIFETDKN 767
Query: 1227 DRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDIELLEG--- 1283
+DL+ ++ FD + K L L ++ + L L F + D+ L+
Sbjct: 768 KDVDLQHMKS-------FDPIIFKHLKAL-QKMNNRELDELQLDFSVVTSDMGLVRNVNL 819
Query: 1284 ---GSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSD 1340
GSK V NV EY+ + L + + + A R G S+ + + P EL
Sbjct: 820 KPNGSKFRVTVENVHEYVRLYVNYHLKQRIASMVDAVRKGISEIISIEWMRMFAPHELQI 879
Query: 1341 LFGAVAEDWSVQTL-------YSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFI 1393
+ E ++ + L +++ D Y + D+ID LSN K+ L+F+
Sbjct: 880 MIAGYEEVFTAKELRKFCELRFAAGTQDINYE---EMFWDVIDKLSN---DDKKALLKFV 933
Query: 1394 TGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRI 1453
TG + P+ GFK+++P+ V++ S+D LP+ TC N L++PKYS++ L++++
Sbjct: 934 TGCSRAPVDGFKSIQPRMGVLVIP-----SSDDELPTSATCMNMLRIPKYSNRTKLEEKL 988
Query: 1454 AQAMTEGSG 1462
A+ G+G
Sbjct: 989 RYAINSGAG 997
>7294742 [O] KOG0941 E3 ubiquitin protein ligase
Length = 973
Score = 89.7 bits (221), Expect = 3e-17
Identities = 97/390 (24%), Positives = 169/390 (42%), Gaps = 53/390 (13%)
Query: 1093 KLRVSRDSLF---LSGIKILKKYGSSPNVLE----IEYKDEEGTGLGP-TLEFYSLMSKE 1144
KL V RD L L G++++ S+P L+ +E+ E+G G + EF+ L+ +E
Sbjct: 621 KLTVRRDQLINDALIGLEMVAM--SNPKDLKKQLVVEFVGEQGIDEGGVSKEFFQLIVEE 678
Query: 1145 FARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLD 1204
+ M+ +T++ T EN + F +G ++ ++ +
Sbjct: 679 IFNPAFGMFIQQEETNNMWFN------------ATPFENGAQ----FTLIGIIIGLAIYN 722
Query: 1205 NRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSI 1264
N L F V + + C DL D+ ++ KSL + D + D
Sbjct: 723 NVTLAVNFPMVVYRKLIGYC-GTFADLSDWSPALY----------KSLKSMLDYQGQDME 771
Query: 1265 KNLDLYFMLPGYDI-------ELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAF 1317
+ + F + D+ EL+ G +LV N E ++ D L ++ Q AF
Sbjct: 772 EVFEQTFKISYSDVFGDVVQHELVPNGQDVLVGQHNKELFVNLYSDFLLNTNIEQQFNAF 831
Query: 1318 RNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDI 1377
R GF S L +L E ++ + ++ L +S + GY+ S I D I
Sbjct: 832 RKGFEMVTDESPLKLLFRPEEIEMLVCGSREFDFVELENSTVYEGGYTEKSQYIQDFWSI 891
Query: 1378 LSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKH-PDGNISADHCLPSVMTCAN 1436
+ ++ K L+F TGS ++P+GG K L+ ++ +H PD + LP+ TC N
Sbjct: 892 VHAMPSEDKHKLLEFTTGSARVPVGGLKCLR---LLITRHGPDSD-----RLPTSHTCFN 943
Query: 1437 YLKLPKYSDKLVLKDRIAQAMTEGSGAFLL 1466
L LP+YS + L++R+ +A+ G +L
Sbjct: 944 VLLLPEYSSREKLEERLMKAINYSKGFGML 973
>HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 862
Score = 89.0 bits (219), Expect = 5e-17
Identities = 78/294 (26%), Positives = 127/294 (42%), Gaps = 40/294 (13%)
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQ 1243
N LK F +G +A ++ + +D F+ F+ K N + L+D E+
Sbjct: 590 NPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY----KRILNKPVGLKDLES------- 638
Query: 1244 FDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDI------ELLEGGSKILVESFNVEEY 1297
D + SL ++ +N ++ +L++YF + + +L G ILV N EEY
Sbjct: 639 IDPEFYNSLIWVKENNIEEC--DLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEY 696
Query: 1298 LIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DWSVQT 1353
+ V + L +GV+ Q AF GF++ P L EL L + E DW
Sbjct: 697 IRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHA 756
Query: 1354 LYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL-----K 1408
+Y Y+ S I + +++ LQF+TG+ +LP+GGF +L
Sbjct: 757 IY------RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGP 810
Query: 1409 PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
KF + + ++ LP TC N L LP Y LK+++ A+ E G
Sbjct: 811 QKFCI------EKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEG 858
>Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 903
Score = 89.0 bits (219), Expect = 5e-17
Identities = 78/294 (26%), Positives = 127/294 (42%), Gaps = 40/294 (13%)
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQ 1243
N LK F +G +A ++ + +D F+ F+ K N + L+D E+
Sbjct: 631 NPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFY----KRILNKPVGLKDLES------- 679
Query: 1244 FDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDI------ELLEGGSKILVESFNVEEY 1297
D + SL ++ +N ++ +L++YF + + +L G ILV N EEY
Sbjct: 680 IDPEFYNSLIWVKENNIEEC--DLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEY 737
Query: 1298 LIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DWSVQT 1353
+ V + L +GV+ Q AF GF++ P L EL L + E DW
Sbjct: 738 IRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHA 797
Query: 1354 LYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL-----K 1408
+Y Y+ S I + +++ LQF+TG+ +LP+GGF +L
Sbjct: 798 IY------RHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGP 851
Query: 1409 PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
KF + + ++ LP TC N L LP Y LK+++ A+ E G
Sbjct: 852 QKFCI------EKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEG 899
>7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 5002
Score = 89.0 bits (219), Expect = 5e-17
Identities = 104/396 (26%), Positives = 162/396 (40%), Gaps = 56/396 (14%)
Query: 1088 RLTRHKLRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGPTL-EFYSLMSKE 1144
R H + V R ++F ++L + G N I ++DEEG G L E+Y ++S+E
Sbjct: 4641 RREEHTVSVRRVTVFEDSFRVLYRLGPEEWKNRFYIVFEDEEGQDAGGLLREWYVIISRE 4700
Query: 1145 FARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLD 1204
M+ + D Y ++ + N L F+ +G ++A+++ D
Sbjct: 4701 IFNP---MYALFCVSPGDRVTY---------MINPSSHANPNHLSYFKFVGRVIAKAVHD 4748
Query: 1205 NRILDFRFNAVFFE-LMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDS 1263
N++L+ F F++ ++ K K+ ++ +D+E K L +L N D S
Sbjct: 4749 NKLLECYFTRSFYKHILGKQVKHTDMESQDYE------------FYKGLDYLMKN--DIS 4794
Query: 1264 IKNLDLYFMLPGYDI------ELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAF 1317
+L F + +L G V N EY+ V + + QL AF
Sbjct: 4795 TLGYELTFSTEVQEFGVTQIRDLKPNGRDTAVTEENKFEYVQLVCQLKMSGSIRQQLDAF 4854
Query: 1318 RNGFSKSFPYSSLLILTPTELSDLFGAVA----EDWSVQTLYSSIHADHGYSMDSPIITD 1373
GF P + I EL L + ED T Y H Y+ S I
Sbjct: 4855 LEGFYDIIPKHLISIFNEQELELLISGLPDIDIEDLKANTEY------HKYTSKSAQIQW 4908
Query: 1374 LIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK-----PKFTVVLKHPDGNISADHCL 1428
L +F + FLQF+TG+ K+PL GF +L+ KF + H D S D L
Sbjct: 4909 FWRALRSFDQADRAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQI---HRDDR-STDR-L 4963
Query: 1429 PSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAF 1464
P TC N L LP Y L+ + +A+ E S F
Sbjct: 4964 PCAHTCFNQLDLPMYKSYDKLRSCLLKAIHECSEGF 4999
>ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase
Length = 746
Score = 88.6 bits (218), Expect = 7e-17
Identities = 94/384 (24%), Positives = 174/384 (44%), Gaps = 54/384 (14%)
Query: 1094 LRVSRDSLFLSGIKILKKYG--SSPNVLEIEYKDEEGTGLGPTL-EFYSLMSKEFARKSL 1150
+ VSR++++ I+I KK + L I +++EEG G E++ L+S+E
Sbjct: 406 ITVSRETVYRDSIEIFKKINVLDARKQLRITFRNEEGVDSGGIRKEYFQLLSQEI----- 460
Query: 1151 KMWKTNSDTSDDEE--EYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRIL 1208
+DE E+ ++ P G E +E +G ++A ++ +N +L
Sbjct: 461 ---------KEDERLFEHTENRIWIRPHEGDGEG--------YEAIGRIIAIALYNNVVL 503
Query: 1209 DFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLD 1268
+ F ++FF+ + + R L+D + + SL L D+ + +LD
Sbjct: 504 NIPFPSLFFKKL----LDRRPTLDDLR-------EISSGIATSLRNLRRLSRDE-VDSLD 551
Query: 1269 LYFMLPGY------DIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFS 1322
L F++ L++ G I + S N+ ++ + + + Q + + GF
Sbjct: 552 LRFVVEHSVDGIPRSYPLVKNGEDIKLTSENMRLFIEKYVEFHTDALIKPQFESIKRGFY 611
Query: 1323 KSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFS 1382
L L P EL + + + ++ + S+ G+ DSPII +I F+
Sbjct: 612 SIIDKDKLAYLDPKELEKIMMG-SNTFDIKAIRSTTTYS-GFREDSPIIVYFWEIFEAFN 669
Query: 1383 TQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPK 1442
++++ LQFITG+ ++P+ G +LK V++++ D LPS TC N L LP+
Sbjct: 670 RKKRKKLLQFITGNDRIPVSGPASLK---LVIMRN---GCDTDR-LPSSQTCFNTLLLPE 722
Query: 1443 YSDKLVLKDRIAQAMTEGSGAFLL 1466
YS K L+ ++ A+ +G FLL
Sbjct: 723 YSSKDKLEGKLETALELTAGFFLL 746
>Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 308
Score = 87.4 bits (215), Expect = 2e-16
Identities = 88/300 (29%), Positives = 130/300 (43%), Gaps = 41/300 (13%)
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFE-LMHKCCKNDRLDLEDFETCIHLVG 1242
N L F+ +G +VA+++ DNR+L+ F F++ ++ K + ++ ED+
Sbjct: 34 NPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYH------- 86
Query: 1243 QFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPGYDIELLE------GGSKILVESFNVEE 1296
+ L +L +N D S DL F + + E G+ ILV N +E
Sbjct: 87 -----FYQGLVYLLEN--DVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKE 139
Query: 1297 YLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAV----AEDWSVQ 1352
Y+ V + + QLAAF GF + P + I T EL L + +D
Sbjct: 140 YVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSN 199
Query: 1353 TLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK---- 1408
T Y H Y +S I L +F + FLQF+TG+ K+PL GF L+
Sbjct: 200 TEY------HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNG 253
Query: 1409 -PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFLLS 1467
KF + H D S D LPS TC N L LP Y L+ + A+ E S F L+
Sbjct: 254 IQKFQI---HRDDR-STDR-LPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA 308
>At3g53090 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1142
Score = 86.3 bits (212), Expect = 3e-16
Identities = 94/383 (24%), Positives = 156/383 (40%), Gaps = 38/383 (9%)
Query: 1096 VSRDSLFLSGIKILKKYGSS-PNVLEIEYKDEEG---TGLGPTLEFYSLMSKEFARKSLK 1151
V R + G + L GS + + + + +E G GL Y +SKEF K
Sbjct: 778 VRRGHVVEDGFQQLNSIGSRLKSSIHVSFVNESGLPEAGLD-----YGGLSKEFLTDITK 832
Query: 1152 MWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFR 1211
+ L P P + + E +++ E LG +V +++ + +LD+
Sbjct: 833 AAFATEYGLFSQTPTSDRLLVPSP----SARHLENGIQMIEFLGRIVGKALYEGILLDYS 888
Query: 1212 FNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYF 1271
F+ VF + + L + L G D +L ++L +Y +D +K L L F
Sbjct: 889 FSHVFIQKL----------LGRYSFIDELSG-LDPELYRNL--MYVKHYDGDLKELCLDF 935
Query: 1272 MLPGYD------IELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSF 1325
+ IEL GG V + N +Y+ + D L + + AF G +
Sbjct: 936 TVTEEFCGKMSIIELKPGGKDTSVTNENKMQYIHAMADYKLNRQIVPFSNAFYRGLTDLI 995
Query: 1326 PYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQ 1385
+ L + E + L D V L + GYS S I +++ F +
Sbjct: 996 SPAWLKLFNAHEFNQLLSGGNHDIDVDDLRRNTKYTGGYSDSSRTIKIFWEVMKGFEPSE 1055
Query: 1386 KRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISAD------HCLPSVMTCANYLK 1439
+ L L+F+T + PL GFK L+P F + D ++ A LPS TC N LK
Sbjct: 1056 RCLLLKFVTSCSRAPLLGFKYLQPTFIIHKVSCDTSLWAAIGGQDVERLPSASTCYNTLK 1115
Query: 1440 LPKYSDKLVLKDRIAQAMTEGSG 1462
LP Y +++++ A+T +G
Sbjct: 1116 LPTYKRASTMREKLLYAITSNAG 1138
>7292061 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1057
Score = 86.3 bits (212), Expect = 3e-16
Identities = 101/384 (26%), Positives = 161/384 (41%), Gaps = 49/384 (12%)
Query: 1094 LRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGPTL-EFYSLMSKEFARKSL 1150
L V+R++L ++ L+ Y S L+I++ EE G EF+ L+ K+
Sbjct: 712 LNVTRENLVQDSLRELQHYSQSDLKKPLKIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKY 771
Query: 1151 KMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDF 1210
M+K EY L L EN ++ +G L ++ + I++
Sbjct: 772 GMFK----------EYEQSRLLWFADLTFETEN------MYFLIGVLCGLAIYNFTIINL 815
Query: 1211 RFN-AVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDL 1269
F A+F +L+ K +DL D Q S+ L D + DD + DL
Sbjct: 816 PFPLALFKKLLGK-----PVDLSDLR-------QLSPPEANSMQSLLDYQGDDFKEVFDL 863
Query: 1270 YFMLPGYDIE-------LLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFS 1322
F + D+ L G++I V N +E++ D K V++ AF GF
Sbjct: 864 TFEI-SRDVFGEAETKCLKPNGNEIAVTLENRQEFVDLYVDFVFNKSVELHYNAFHKGFM 922
Query: 1323 KSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFS 1382
K + I P EL + ED+ Q L + GY+ I +++ + S
Sbjct: 923 KVCSGRVIHIFQPEELMAVVVG-NEDYDWQALQDNCEYREGYTSVDDTIKWFWEVIHDMS 981
Query: 1383 TQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPK 1442
+K+ FL F+TGS ++P+ G K LK + PD + LP TC N L LP+
Sbjct: 982 EAEKKSFLLFLTGSDRIPIQGMKALK---LTIQPTPD-----ERFLPVAHTCFNLLDLPR 1033
Query: 1443 YSDKLVLKDRIAQAMTEGSGAFLL 1466
Y K LK ++ QA+ + G L+
Sbjct: 1034 YKTKERLKYKLLQAIQQTQGFSLV 1057
>7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 949
Score = 84.3 bits (207), Expect = 1e-15
Identities = 101/403 (25%), Positives = 167/403 (41%), Gaps = 66/403 (16%)
Query: 1083 LHQLGRLTRH-KLRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGP-TLEFY 1138
L Q L H K+ V+R +LF + + + L I ++ EEG G + E++
Sbjct: 584 LCQSNALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWF 643
Query: 1139 SLMSKEFARKSLKMW----KTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENL 1194
L+S E ++ K N + YV N L+ F+ +
Sbjct: 644 FLLSHEVLNPMYCLFEYANKNNYSLQINPASYV----------------NPDHLQYFKFI 687
Query: 1195 GTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAF 1254
G +A ++ R + F F++ M N +L ++D ET D + SL +
Sbjct: 688 GRFIAMALYHGRFIYSGFTMPFYKRM----LNKKLTIKDIET-------IDPEFYNSLIW 736
Query: 1255 LYDNRHDDSIKNLDLYFMLPGYDI-------ELLEGGSKILVESFNVEEYLIRVFDQFLG 1307
+ DN D+ L+L+F + +++ EL E G K V N EEY+ + + +
Sbjct: 737 VKDNNIDEC--GLELWFSVD-FEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMT 793
Query: 1308 KGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAV----AEDWSVQTLYSSIHADHG 1363
+G++ Q F GF++ P L EL + + EDW T+Y
Sbjct: 794 RGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIY------RH 847
Query: 1364 YSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK----PKFTVVLKHPD 1419
Y+ +S + + +++ LQF+TG+ ++P+GGF L P+ + K
Sbjct: 848 YNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEK--- 904
Query: 1420 GNISADHCLPSVMTCANYLKLPKYS--DKLVLKDRIAQAMTEG 1460
+ + LP TC N L LP Y D+LV K A TEG
Sbjct: 905 --VGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEG 945
>HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 854
Score = 84.0 bits (206), Expect = 2e-15
Identities = 98/418 (23%), Positives = 175/418 (41%), Gaps = 70/418 (16%)
Query: 1065 YWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNVLE---- 1120
Y+R+KL P + P R ++++ R+++F + + P+VL+
Sbjct: 482 YFRKKL-----KKPADIP-------NRFEMKLHRNNIFEESYRRIMSV-KRPDVLKARLW 528
Query: 1121 IEYKDEEGTGLGPTL-EFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGT 1179
IE++ E+G G E++ L+SKE +++ ++ + Y L P G
Sbjct: 529 IEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSAT-----DNYT---LQINPNSGL 580
Query: 1180 TEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIH 1239
NE L F +G + ++ ++LD F F+++M ++ L D E+
Sbjct: 581 C---NEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMM----LGKQITLNDMESV-- 631
Query: 1240 LVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKILVESFN 1293
D + SL ++ +N + LDL F + Y ++L GS+I+V + N
Sbjct: 632 -----DSEYYNSLKWILENDPTE----LDLMFCIDEENFGQTYQVDLKPNGSEIMVTNEN 682
Query: 1294 VEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DW 1349
EY+ V V Q+ AF GF++ P + I EL L + + DW
Sbjct: 683 KREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDW 742
Query: 1350 SVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL-- 1407
++Y +GY + P+I + +++ LQF+TG+ ++P+ GF L
Sbjct: 743 RQHSIYK-----NGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYG 797
Query: 1408 ---KPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
FT+ + LP TC N L LP Y L++++ A+ G
Sbjct: 798 SNGPQLFTI------EQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQG 849
>Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 955
Score = 84.0 bits (206), Expect = 2e-15
Identities = 98/418 (23%), Positives = 175/418 (41%), Gaps = 70/418 (16%)
Query: 1065 YWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSSPNVLE---- 1120
Y+R+KL P + P R ++++ R+++F + + P+VL+
Sbjct: 583 YFRKKL-----KKPADIP-------NRFEMKLHRNNIFEESYRRIMSV-KRPDVLKARLW 629
Query: 1121 IEYKDEEGTGLGPTL-EFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGT 1179
IE++ E+G G E++ L+SKE +++ ++ + Y L P G
Sbjct: 630 IEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSAT-----DNYT---LQINPNSGL 681
Query: 1180 TEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIH 1239
NE L F +G + ++ ++LD F F+++M ++ L D E+
Sbjct: 682 C---NEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMM----LGKQITLNDMESV-- 732
Query: 1240 LVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKILVESFN 1293
D + SL ++ +N + LDL F + Y ++L GS+I+V + N
Sbjct: 733 -----DSEYYNSLKWILENDPTE----LDLMFCIDEENFGQTYQVDLKPNGSEIMVTNEN 783
Query: 1294 VEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE----DW 1349
EY+ V V Q+ AF GF++ P + I EL L + + DW
Sbjct: 784 KREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDW 843
Query: 1350 SVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL-- 1407
++Y +GY + P+I + +++ LQF+TG+ ++P+ GF L
Sbjct: 844 RQHSIYK-----NGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYG 898
Query: 1408 ---KPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
FT+ + LP TC N L LP Y L++++ A+ G
Sbjct: 899 SNGPQLFTI------EQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQG 950
>YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 809
Score = 83.6 bits (205), Expect = 2e-15
Identities = 92/360 (25%), Positives = 149/360 (40%), Gaps = 54/360 (15%)
Query: 1119 LEIEYKDEEGTGLGP-TLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLL 1177
L I++ EEG G + EF+ L+S E +++ ++ Y + P
Sbjct: 484 LMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSA--------YDNYTIQINPNS 535
Query: 1178 GTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETC 1237
G E+ L F+ +G +V + R LD A F ++K ++ L+D E
Sbjct: 536 GINPEH----LNYFKFIGRVVGLGVFHRRFLD----AFFVGALYKMMLRKKVVLQDMEGV 587
Query: 1238 IHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKILVES 1291
D ++ SL ++ +N D LDL F ++L G I V
Sbjct: 588 -------DAEVYNSLNWMLENSIDGV---LDLTFSADDERFGEVVTVDLKPDGRNIEVTD 637
Query: 1292 FNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE---- 1347
N +EY+ + V Q AF +GF++ P + + EL L G +AE
Sbjct: 638 GNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIE 697
Query: 1348 DWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL 1407
DW T Y GY +I +S + +Q+ LQF TG+ ++P+ GFK+L
Sbjct: 698 DWKKHTDY------RGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDL 751
Query: 1408 K-----PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
+ +FT+ G + LP TC N + LP+Y D +K ++ A+ E G
Sbjct: 752 QGSDGPRRFTI---EKAGEVQQ---LPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIG 805
>SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase
Length = 807
Score = 83.6 bits (205), Expect = 2e-15
Identities = 90/402 (22%), Positives = 175/402 (43%), Gaps = 66/402 (16%)
Query: 1094 LRVSRDSLFLSGIKILKKYGSS-PNVLEIEYKDEEGTGLGPTL-EFYSLMSKEFARKSLK 1151
+RV RD L ++ + L++E+ EEG G E+ L++++
Sbjct: 435 IRVRRDRLLEDSLRQINDRNKDFRKALKVEFLGEEGIDAGGLKREWLLLLTRKVFSPEFG 494
Query: 1152 MWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFR 1211
++ ++S+ L + K + + G L+ ++ ++ LD +
Sbjct: 495 LFVNCEESSN--------------YLWFNYSHRSKEIDYYHMSGILMGIAIHNSINLDVQ 540
Query: 1212 FNAVFFELMHKCCKNDRLDLEDFETCIH------LVGQFDVQLGKSLAFLYDNRHDDSIK 1265
F++ + + + DL+DF+ ++ L+ + DV+ L F + + + +
Sbjct: 541 MPRAFYKKLLQLPLSFN-DLDDFQPSLYRGLKELLLFEGDVKNTYGLNFTINLKAVEGFR 599
Query: 1266 NLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSF 1325
+EL EGGS++ V++ N +EY++R D L V Q +AF +GF K
Sbjct: 600 T-----------VELKEGGSELSVDNENRKEYVLRYVDYLLNTTVKKQFSAFFDGFMKVC 648
Query: 1326 PYSSLLILTPTELSDLFGAVAE--DW-----------------------SVQTLYSSIHA 1360
+++ + E+S L E DW S ++ +S +
Sbjct: 649 GGNAISLFQDNEISKLIRGSEEVIDWELLKNVCVYDFYDQNAISNSISESEPSMTASKYL 708
Query: 1361 DHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDG 1420
H + II D++S++S + ++LFL F+TGS ++P G N + + +V+ PD
Sbjct: 709 CHSFVSKRKIILWFWDLISHYSLKMQKLFLIFVTGSDRIPATGAHNFQLRISVL--GPDS 766
Query: 1421 NISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
+ LP TC N+L + +YS + LK ++ A+ E +G
Sbjct: 767 D-----QLPISHTCFNHLCIWEYSSREKLKKKLDTALLETNG 803
>Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 900
Score = 83.6 bits (205), Expect = 2e-15
Identities = 106/424 (25%), Positives = 173/424 (40%), Gaps = 64/424 (15%)
Query: 1056 SYGYGRLIQYWREKLADQHHSNPTENPLHQLGRLTRHKLRVSRDSLFLSGIKILKKYGSS 1115
S Y R +++R KL Q N + + + V DS I +K+
Sbjct: 519 SRDYKRKYEFFRRKLKKQ-------NDIPNKFEMKLRRATVLEDSY--RRIMGVKRADFL 569
Query: 1116 PNVLEIEYKDEEGTGLGPTL-EFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPG 1174
L IE+ E+G G E++ L+SKE +++ ++ + Y L
Sbjct: 570 KARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSAT-----DNYT---LQIN 621
Query: 1175 PLLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELM-HKCCKNDRLDLED 1233
P G NE L F+ +G + ++ ++LD F F+++M HK + L D
Sbjct: 622 PNSGLC---NEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHK-----PITLHD 673
Query: 1234 FETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKI 1287
E+ D + SL ++ +N + LDL F++ + EL GGS+I
Sbjct: 674 MESV-------DSEYYNSLRWILENDPTE----LDLRFIIDEELFGQTHQHELKNGGSEI 722
Query: 1288 LVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE 1347
+V + N +EY+ V + Q+AAF+ GF + P + I EL L + +
Sbjct: 723 VVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGD 782
Query: 1348 ----DWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGG 1403
DW T Y +GYS + +I + ++++ LQF+TG+ ++P+ G
Sbjct: 783 VDVNDWREHTKYK-----NGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNG 837
Query: 1404 FKNL-----KPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMT 1458
F L FTV LP TC N L LP Y L D++ A+
Sbjct: 838 FAELYGSNGPQSFTV------EQWGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAIE 891
Query: 1459 EGSG 1462
G
Sbjct: 892 NTQG 895
>SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 786
Score = 83.2 bits (204), Expect = 3e-15
Identities = 75/294 (25%), Positives = 127/294 (42%), Gaps = 41/294 (13%)
Query: 1184 NEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQ 1243
N + L F +G ++ ++ R LD A F ++K ++ L D E+
Sbjct: 515 NPEHLNYFRFIGRVIGLAIFHRRFLD----AFFVVSLYKKLLRKKVSLADMES------- 563
Query: 1244 FDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKILVESFNVEEY 1297
D + +SL ++ +N D LDL F + +EL+ G I V N ++Y
Sbjct: 564 IDAEFYRSLKWVLEN---DITGILDLTFSVEEDHFGEVRTVELITNGENIEVTEENKKKY 620
Query: 1298 LIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVA----EDWSVQT 1353
+ V + + K V+ Q AF +GF + + + EL L G ++ EDW T
Sbjct: 621 VDLVTEWRVSKRVEQQFNAFYSGFVELVSPDLVNVFDERELELLIGGISDVDVEDWKSHT 680
Query: 1354 LYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLK----- 1408
Y + Y P+I +I++ + + + LQF TG+ ++P+ GF++L+
Sbjct: 681 EYRT------YIATDPVIKWFWEIIAGWKNEDRSKLLQFATGTSRIPVNGFRDLQGSDGP 734
Query: 1409 PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
KFT+ LP TC N L LP Y K L ++++ A+ G
Sbjct: 735 RKFTI------EKAGTPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAVENTVG 782
>Hs10863903_1 [O] KOG0168 Putative ubiquitin fusion degradation protein
Length = 1342
Score = 82.4 bits (202), Expect = 5e-15
Identities = 70/231 (30%), Positives = 102/231 (43%), Gaps = 21/231 (9%)
Query: 118 GDVAEGEEADSERAFGRSLPDLLQELGRSEGFFG-------------VSRGNSRYLKLIE 164
G GE + GR L LL+ G FG + G S + +
Sbjct: 385 GMTTSGESESDDSEMGR-LQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLL 443
Query: 165 NVLQAEDDPYIAMESLRELSEQLLMLNPLIADRIIPSGKLMDALIHVXXXXXXXXXXXXX 224
LQA D+ ++++ E+ + L+M N P ++ ALI +
Sbjct: 444 QGLQASDESQ-QLQAVIEMCQLLVMGNEETLGGF-PVKSVVPALITLLQMEHNFDIMNH- 500
Query: 225 XIACRCLYNYYEMNPEMIEVSVNRDIIEILRGKLNEISYIDLAEQVLECLEFISRVHGSK 284
ACR L E P V V D I + KL I ID+AEQ L LE +SR H
Sbjct: 501 --ACRALTYMMEALPRSSAVVV--DAIPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKA 556
Query: 285 ILRSGTLLSCLQYLDFFTVHAQKKSLSIVANSCARAKESDFEVVSEIFPIL 335
IL++G L CL YL+FF+++AQ+ +L+I AN C +F V++ P+L
Sbjct: 557 ILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLL 607
>Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1572
Score = 80.9 bits (198), Expect = 1e-14
Identities = 99/388 (25%), Positives = 162/388 (41%), Gaps = 56/388 (14%)
Query: 1093 KLRVSRDSLFLSGIKILKKYGSSP---NVLEIEYKDEEGTGL-GPTLEFYSLMSKEFARK 1148
KL + RD L + Y N L + + EEG GP+ EF+ L+S+E
Sbjct: 1217 KLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNP 1276
Query: 1149 SLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRIL 1208
+++ +++ T + P+ + ++E F G ++ +++ +L
Sbjct: 1277 YYGLFEYSAND--------TYTVQISPMSAFVDNHHE----WFRFSGRILGLALIHQYLL 1324
Query: 1209 DFRFNAVFFE-LMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNL 1267
D F F++ L+ C DL D E D + +SL ++ DN D L
Sbjct: 1325 DAFFTRPFYKALLRILC-----DLSDLE-------YLDEEFHQSLQWMKDNDIHDI---L 1369
Query: 1268 DLYFMLPGY------DIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGF 1321
DL F + + EL GG+ I V N +EY+ R+ + +GV Q + GF
Sbjct: 1370 DLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGF 1429
Query: 1322 SKSFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLIDI 1377
+ + + EL + AE DW T Y GY + +I
Sbjct: 1430 YEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRG-----GYHDNHIVIRWFWAA 1484
Query: 1378 LSNFSTQQKRLFLQFITGSPKLPLGGFKNLK----PKFTVVLKHPDGNISADHCLPSVMT 1433
+ F+ +Q+ LQF+TG+ +P GF +L+ P+ V K G I+A LP T
Sbjct: 1485 VERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKW--GKITA---LPRAHT 1539
Query: 1434 CANYLKLPKYSDKLVLKDRIAQAMTEGS 1461
C N L LP Y +L +++ A+ E S
Sbjct: 1540 CFNRLDLPPYPSFSMLYEKLLTAVEETS 1567
>CE29116 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1019
Score = 80.9 bits (198), Expect = 1e-14
Identities = 98/359 (27%), Positives = 151/359 (41%), Gaps = 52/359 (14%)
Query: 1116 PNVLEIEYKDEEGTGLGPTLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGP 1175
P + I +D + G G EF+ L+ ++ + M+ S+DEE ++
Sbjct: 695 PLKVNIAGEDADDAG-GVRKEFFILVMRKILQSDYGMF------SEDEESHLVW------ 741
Query: 1176 LLGTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFE 1235
G E ++ + F LG LV S+ ++ I+ F F ++K + DLED
Sbjct: 742 FSGLPSEFCDR--EQFHQLGRLVGLSIYNHSIVPFPFPLA----LYKYLLDTPPDLEDL- 794
Query: 1236 TCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLP------GYDIELLEGGSKILV 1289
C + GK L L DD L F + + ELL GG++ V
Sbjct: 795 -C-----ELSPSEGKGLKMLLSYEEDDVEDVFGLNFCISFNILGETHTTELLSGGTEKPV 848
Query: 1290 ESFNVEEYLIRVFDQFLGKGVDMQLAA----FRNGFSKSFPYSSLLILTPTELSDLF-GA 1344
+ N +EY+ L G + ++A FR GFS+S +L P EL ++ G
Sbjct: 849 TNANRDEYVRLYVHHRLELGYNGEIAQQALLFRKGFSESLHSRTLRFFQPCELKEMIVGN 908
Query: 1345 VAEDWSVQTLYSSIHADHG-YSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGG 1403
DW+ + I G YS P I + ++R FLQF+TGS ++P+ G
Sbjct: 909 ENYDWNE---FRDILMYRGEYSSSHPTIQAFWKAFFALTDDERRKFLQFLTGSTRIPVSG 965
Query: 1404 FKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSD--KLVLKDRIAQAMTEG 1460
++ L H SA LP TC N L LP +D +L+ + RI+ TEG
Sbjct: 966 WEEL---------HAAIQPSAPESLPVAHTCFNLLDLPNIADDVELLRRLRISIEHTEG 1015
>7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 388
Score = 80.9 bits (198), Expect = 1e-14
Identities = 87/356 (24%), Positives = 150/356 (41%), Gaps = 49/356 (13%)
Query: 1119 LEIEYKDEEGTGLG-PTLEFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLL 1177
L + + EEG G P+ EF+ L+S+E +++ +++ T + PL
Sbjct: 60 LAVLWDTEEGLDYGGPSREFFFLLSRELFNPYYGLFEYSAND--------TYTVQVSPLS 111
Query: 1178 GTTEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETC 1237
+ ++ F G ++ +++ +LD F F++ + + + L D E+
Sbjct: 112 AFVDNCHD----WFRFSGRVLGLALVHQYLLDAFFTRPFYKALLRL----PVALSDLES- 162
Query: 1238 IHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKILVES 1291
D + +SL ++ DN + +L L F + D EL GG I++
Sbjct: 163 ------LDNEFHQSLQWIRDNDIGTGV-DLGLTFCVTEELLGSVVDRELKPGGKNIIINE 215
Query: 1292 FNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAE---- 1347
N +EYL R+ L +GV Q + GF + + + EL + AE
Sbjct: 216 KNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAGTAEIDTN 275
Query: 1348 DWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL 1407
DW + T Y S GY + +I ++ FS +Q+ LQF+TG+ +P GF L
Sbjct: 276 DWRLNTEYRS-----GYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSAL 330
Query: 1408 K----PKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTE 1459
+ P+ + K N LP TC N L LP Y +L +++ A+ E
Sbjct: 331 RGSTGPRRFCIEKWGKPN-----ALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEE 381
>At4g38610 [O] KOG0168 Putative ubiquitin fusion degradation protein
Length = 1083
Score = 80.1 bits (196), Expect = 2e-14
Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 24/242 (9%)
Query: 109 DQRSGESGDGDVAEGEEADSE-------RAFGRSLPDLLQELGRSEGFFGVSRGNSRYLK 161
D E G+G + + R G L DLL G G S N R K
Sbjct: 140 DDNDSEDGNGGFMHPNMSSASSALQGLLRKLGAGLDDLLPSSGI--GSASSSHLNGRMKK 197
Query: 162 LIENVLQAEDDPYIAMESLRELSEQLLM-----LNPLIADRIIPSGKLMDALIHVXXXXX 216
++ L+AE + +E+L +L E L + L+ D +P L+ L H
Sbjct: 198 ILSG-LRAEGEEGKQVEALTQLCEMLSIGTEDSLSTFSVDSFVPV--LVGLLNH------ 248
Query: 217 XXXXXXXXXIACRCLYNYYEMNPEMIEVSVNRDIIEILRGKLNEISYIDLAEQVLECLEF 276
+A R L + ++ P V+ + L +L I Y+DLAEQ L+ L+
Sbjct: 249 -ESNPDIMLLAARALTHLCDVLPSSCAAVVHYGAVSCLVARLLTIEYMDLAEQSLQALKK 307
Query: 277 ISRVHGSKILRSGTLLSCLQYLDFFTVHAQKKSLSIVANSCARAKESDFEVVSEIFPILK 336
IS+ H + LR+G L++ L YLDFF+ Q+ +LS AN C + + V E P+L
Sbjct: 308 ISQEHPTACLRAGALMAVLSYLDFFSTGVQRVALSTAANMCKKLPSDASDYVMEAVPLLT 367
Query: 337 SI 338
++
Sbjct: 368 NL 369
>Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase
Length = 218
Score = 79.3 bits (194), Expect = 4e-14
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
Query: 1280 LLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELS 1339
L GG KI V + N +EY+ D L K + Q AAF GF ++L++L P E+
Sbjct: 41 LKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEV- 99
Query: 1340 DLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKL 1399
++ + D + L S D GY+ I D++ F ++ L F TGS ++
Sbjct: 100 EILVCGSPDLDMHALQRSTQYD-GYAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRV 158
Query: 1400 PLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTE 1459
P+GG +L K + N ++ +CLP TC N L LP Y K LK ++ ++
Sbjct: 159 PVGGMADLNFKIS-------KNETSTNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISN 211
Query: 1460 GSG 1462
G
Sbjct: 212 SEG 214
>Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1068
Score = 79.0 bits (193), Expect = 5e-14
Identities = 90/360 (25%), Positives = 152/360 (42%), Gaps = 61/360 (16%)
Query: 1136 EFYSLMSKEFARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLG 1195
EF + K +L ++KT TS DE L+P P T +E L+LFE +G
Sbjct: 733 EFLEEIIKRVFDPALNLFKT---TSGDER------LYPSP----TSYIHENYLQLFEFVG 779
Query: 1196 TLVARSMLDNRILDFRFNAVFFELM----HKCCKNDRLDLEDFETCIHLVGQFDVQLGKS 1251
++ +++ + ++D F + F + H F + + + D + K+
Sbjct: 780 KMLGKAVYEGIVVDVPFASFFLSQLLGHHHSV----------FYSSVDELPSLDSEFYKN 829
Query: 1252 LAFLYDNRHDDSIKNLDLYFMLPGYDI---------ELLEGGSKILVESFNVEEYLIRVF 1302
L + R+D I +L L YD EL+ GG I V + N Y+ +
Sbjct: 830 LTSI--KRYDGDITDLGLTL---SYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMA 884
Query: 1303 DQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADH 1362
+ + Q AA +GF + + + EL L + ++ L
Sbjct: 885 HFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYG 944
Query: 1363 GYSMDSPIITDLIDIL-SNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTV-VLKHPDG 1420
G+ +I L DIL S+F+ ++ +FL+F+T + PL GF LKP F++ ++ D
Sbjct: 945 GFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDD 1004
Query: 1421 NISADHC------------------LPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
+ D LP+ TC N LKLP YS K VL++++ A++ +G
Sbjct: 1005 QDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTG 1064
>7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 971
Score = 78.2 bits (191), Expect = 9e-14
Identities = 64/213 (30%), Positives = 96/213 (45%), Gaps = 18/213 (8%)
Query: 1262 DSIKNLDLYFMLPGYD---------IELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDM 1312
D+ L+LYF+ YD IEL+ G+K V + +YL + Q L V
Sbjct: 764 DATDTLELYFVEEMYDSSSGQLSKTIELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKD 823
Query: 1313 QLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYSSIHADHGYSMD-SPII 1371
++ +F G + P + L I EL L E +S+ + + H +G S + ++
Sbjct: 824 EVDSFLKGLNSIIPDNLLSIFDENELELLMCGTGE-YSISD-FKAHHIANGNSAEFRRVL 881
Query: 1372 TDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSV 1431
+SNFS + LQF TG +LP GGF+ L P+F + GN LP+
Sbjct: 882 AWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQELNPQFQITAAPTFGN------LPTA 935
Query: 1432 MTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAF 1464
TC N L LP Y + + A++EGS F
Sbjct: 936 HTCFNQLCLPDYESYEQFEKSLLLAISEGSEGF 968
>Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1606
Score = 75.5 bits (184), Expect = 6e-13
Identities = 97/389 (24%), Positives = 158/389 (39%), Gaps = 58/389 (14%)
Query: 1093 KLRVSRDSLFLSGIKILKKYGSSP---NVLEIEYKDEEGTGL-GPTLEFYSLMSKEFARK 1148
KL + RD L + Y N L + + EEG GP+ EF+ L+S+E
Sbjct: 1251 KLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNP 1310
Query: 1149 SLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRIL 1208
+++ +++ T + P+ E + L+ F G ++ +++ +L
Sbjct: 1311 YYGLFEYSAND--------TYTVQISPMSAFVENH----LEWFRFSGRILGLALIHQYLL 1358
Query: 1209 DFRFNAVFFE-LMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNL 1267
D F F++ L+ C DL D E D + +SL ++ DN D L
Sbjct: 1359 DAFFTRPFYKALLRLPC-----DLSDLE-------YLDEEFHQSLQWMKDNNITDI---L 1403
Query: 1268 DLYFMLPGY------DIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGF 1321
DL F + + EL GG+ V N +EY+ R+ + +GV Q A GF
Sbjct: 1404 DLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGF 1463
Query: 1322 SKSFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLIDI 1377
+ + + EL + AE DW T Y GY +I
Sbjct: 1464 YEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRG-----GYHDGHLVIRWFWAA 1518
Query: 1378 LSNFSTQQKRLFLQFITGSPKLPLGGFKNLK-----PKFTVVLKHPDGNISADHCLPSVM 1432
+ F+ +Q+ LQF+TG+ +P GF L+ +F + G I++ LP
Sbjct: 1519 VERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI---EKWGKITS---LPRAH 1572
Query: 1433 TCANYLKLPKYSDKLVLKDRIAQAMTEGS 1461
TC N L LP Y +L +++ A+ E S
Sbjct: 1573 TCFNRLDLPPYPSYSMLYEKLLTAVEETS 1601
>7296816 [O] KOG0168 Putative ubiquitin fusion degradation protein
Length = 1518
Score = 75.5 bits (184), Expect = 6e-13
Identities = 72/241 (29%), Positives = 108/241 (43%), Gaps = 27/241 (11%)
Query: 110 QRSGESGDGDVAEGEEADSERAFGRSLPDLLQELGRSEGFFGV-----------SRGNSR 158
Q SG + E DSE GR L LL+ G FG + GNS
Sbjct: 113 QHGSGSGAAAAVDSESDDSE--VGR-LQALLEARGLPPHLFGALGPRVTHILHRTIGNSS 169
Query: 159 YLKLIENV--LQAEDDPYIAMESLRELSEQLLMLNPLIADRI--IPSGKLMDALIHVXXX 214
K + + LQ+ D+ +++ E+ + L+M N D + P +++ ALI +
Sbjct: 170 SSKANQLLQGLQSHDESQ-QLQAAIEMCQMLVMGNE---DTLAGFPIKQVVPALIQLLRM 225
Query: 215 XXXXXXXXXXXIACRCLYNYYEMNPEMIEVSVNRDIIEILRGKLNEISYIDLAEQVLECL 274
ACR L E P V + + + KL I +D+AEQ L L
Sbjct: 226 EHNFDIMNN---ACRALAYMLEALPRSSGTVV--EAVPVFLEKLQVIQCMDVAEQSLSAL 280
Query: 275 EFISRVHGSKILRSGTLLSCLQYLDFFTVHAQKKSLSIVANSCARAKESDFEVVSEIFPI 334
E +SR H IL++ + +CL YLDFF++ AQ+ +L+I AN C +F V+E P+
Sbjct: 281 EILSRRHNKAILQANGISACLTYLDFFSIVAQRAALAIAANCCLNMHPEEFHFVAESLPL 340
Query: 335 L 335
L
Sbjct: 341 L 341
>YJR036c [O] KOG0941 E3 ubiquitin protein ligase
Length = 892
Score = 75.1 bits (183), Expect = 8e-13
Identities = 87/395 (22%), Positives = 168/395 (42%), Gaps = 53/395 (13%)
Query: 1093 KLRVSRDSLFLSGIKILKKY-GSSPNVLEIEYKDEEGTGLGPTL-EFYSLMSKE------ 1144
K++V RD + ++ +K++ G L IE+ +E G G E++ L++K
Sbjct: 522 KIKVRRDVISHDSLRCIKEHQGDLLKSLRIEFVNEPGIDAGGLRKEWFFLLTKSLFNPMN 581
Query: 1145 ----FARKSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVAR 1200
+ ++S + W + D+ + L+L+ G ++
Sbjct: 582 GLFIYIKESSRSWFAIDPPNFDKSK-----------------GKNSQLELYYLFGVVMGL 624
Query: 1201 SMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDF-----ETCIHLVGQFDVQLGK----- 1250
++ ++ ILD +F ++ K C ++ L ED+ ET +L+ +
Sbjct: 625 AIFNSTILDLQFPKALYK---KLC-SEPLSFEDYSELFPETSRNLIKMLNYTEDNFEDVF 680
Query: 1251 SLAFLYDNRHDDSIKNLDLYFMLPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGV 1310
SL F R+++ I N D +EL E G + + N E++++ + +L K +
Sbjct: 681 SLTFETTYRNNNWILN-DSKSSKEYVTVELCENGRNVPITQSNKHEFVMKWVEFYLEKSI 739
Query: 1311 DMQLAAFRNGFSKSFPY-SSLLILTPTELSDLFGAVAED--WSVQTLYSSIHADHGYSMD 1367
+ Q F +GF + F +S+ + EL L E + ++L S G+S D
Sbjct: 740 EPQYNKFVSGFKRVFAECNSIKLFNSEELERLVCGDEEQTKFDFKSLRSVTKYVGGFSDD 799
Query: 1368 SPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHC 1427
S + +I+ ++ ++ LQF+T S ++P G + K +++ H +
Sbjct: 800 SRAVCWFWEIIESWDYPLQKKLLQFVTASDRIPATGISTIPFKISLLGSHDSDD------ 853
Query: 1428 LPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
LP TC N + L YS K L+ ++ A+ E G
Sbjct: 854 LPLAHTCFNEICLWNYSSKKKLELKLLWAINESEG 888
>Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1024
Score = 72.0 bits (175), Expect = 7e-12
Identities = 56/218 (25%), Positives = 93/218 (41%), Gaps = 11/218 (5%)
Query: 1248 LGKSLAFLYDNRHDDSIKNLDLYFML--PGYDIELLEGGSKILVESFNVEEYLIRVFDQF 1305
LGK+L L D+ D+ + ++F + D L+ GS I V N +Y+ + +
Sbjct: 813 LGKNLQTLLDDEGDNFEEVFYIHFNVHWDRNDTNLIPNGSSITVNQTNKRDYVSKYINYI 872
Query: 1306 LGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLF-GAVAEDWSVQTLYSSIHADHGY 1364
V FR GF K + + P EL D+ G DW +T + + GY
Sbjct: 873 FNDSVKAVYEEFRRGFYKMCDEDIIKLFHPEELKDVIVGNTDYDW--KTFEKNARYEPGY 930
Query: 1365 SMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISA 1424
+ P I + ++K+ FL F+TG+ +L + N+K F P+
Sbjct: 931 NSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKITFCC----PESWNER 986
Query: 1425 DHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
D +TC + L LPKYS +++ + +A+ G
Sbjct: 987 DPI--RALTCFSVLFLPKYSTMETVEEALQEAINNNRG 1022
>Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase
Length = 379
Score = 71.6 bits (174), Expect = 9e-12
Identities = 64/253 (25%), Positives = 105/253 (41%), Gaps = 18/253 (7%)
Query: 1213 NAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFM 1272
N F ++K + + LED + + +LGKSL + D+ DD L + F
Sbjct: 133 NLPFPLALYKKLLDQKPSLEDLK-------ELSPRLGKSLQEVLDDAADDIGDALCIRFS 185
Query: 1273 L--PGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSL 1330
+ D++L+ G I V+ N +Y+ + D V F+ GF + L
Sbjct: 186 IHWDQNDVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEIL 245
Query: 1331 LILTPTEL-SDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLF 1389
P EL + + G DW + + + GY P I + +K+ F
Sbjct: 246 RHFYPEELMTAIIGNTDYDW--KQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKF 303
Query: 1390 LQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVL 1449
L F+TG +L G + K +V + P+ DH P+ +TC N L LPKYS +
Sbjct: 304 LFFLTGRDRLHARGIQ----KMEIVFRCPETFSERDH--PTSITCHNILSLPKYSTMERM 357
Query: 1450 KDRIAQAMTEGSG 1462
++ + A+ G
Sbjct: 358 EEALQVAINNNRG 370
>Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1050
Score = 71.6 bits (174), Expect = 9e-12
Identities = 70/279 (25%), Positives = 119/279 (42%), Gaps = 27/279 (9%)
Query: 1191 FENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGK 1250
F +G ++ ++ ++D F ++K N + LED + + G+
Sbjct: 788 FHLIGITCGLAIYNSTVVDLHFPLA----LYKKLLNVKPGLEDLK-------ELSPTEGR 836
Query: 1251 SLAFLYDNRHDDSIKNLDLYFML--PGYDI----ELLEGGSKILVESFNVEEYLIRVFDQ 1304
SL L D +D + L F + Y + +L+ GG + V N +E++ +
Sbjct: 837 SLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNY 896
Query: 1305 FLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLF-GAVAEDWSVQTLYSSIHADHG 1363
V AF +GF K L + P+EL + G +W + L +
Sbjct: 897 VFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNW--EELEETAIYKGD 954
Query: 1364 YSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNIS 1423
YS P + + F ++K+ FL F+TGS ++P+ G +L+ +V++ S
Sbjct: 955 YSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQ----IVIQ---STAS 1007
Query: 1424 ADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
+ LP TC N L LPKYS K +L R+ QA+ G
Sbjct: 1008 GEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEG 1046
>Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 823
Score = 69.7 bits (169), Expect = 3e-11
Identities = 91/391 (23%), Positives = 160/391 (40%), Gaps = 54/391 (13%)
Query: 1094 LRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLG-PTLEFYSLMSKEFARKSL 1150
L+VSR +L S +K + + S E+ ++DEE G P E++ L+ K +
Sbjct: 464 LKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTN 523
Query: 1151 KMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDN----- 1205
+++ SD + + P P LK++E G LV + + ++
Sbjct: 524 QLFTRFSDNNQ-------ALVHPNP-----NRPAHLRLKMYEFAGRLVGKCLYESSLGGA 571
Query: 1206 --RILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKS-LAFLYDNRHDD 1262
+++ RF F + R+ + FET D + KS + F+ +N
Sbjct: 572 YKQLVRARFTRSFLAQIIGL----RMHYKYFETD-------DPEFYKSKVCFILNN---- 616
Query: 1263 SIKNLDLYFMLPGYD--------IELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQL 1314
+ ++L F Y+ +EL+ GG++ V + N YL + L V ++
Sbjct: 617 DMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEV 676
Query: 1315 AAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYS-SIHADHGYSMDSPIITD 1373
F G ++ P + L I EL +L D SV + ++ + ++
Sbjct: 677 EHFLKGLNELVPENLLAIFDENEL-ELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRW 735
Query: 1374 LIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMT 1433
++S+ + ++ LQF TGS +LP GGF L P F ++ LP+ T
Sbjct: 736 FWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIA------APTHSTLPTAHT 789
Query: 1434 CANYLKLPKYSDKLVLKDRIAQAMTEGSGAF 1464
C N L LP Y + + A++EG F
Sbjct: 790 CFNQLCLPTYDSYEEVHRMLQLAISEGCEGF 820
>CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 889
Score = 67.4 bits (163), Expect = 2e-10
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 42/267 (15%)
Query: 1207 ILDFR-FNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIK 1265
++DF+ +A F++ M+ +ND +DLE ++F+Y + + +
Sbjct: 646 LMDFKESDAEFYKSMNWLLENDVVDLE-------------------MSFVYSSMVNGKVS 686
Query: 1266 NLDLYFM----LPGYDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGF 1321
+L L + L + EL+ GG +V N E++ + + +GV+ L F
Sbjct: 687 DLTLSSIVSVALQLAEQELVPGGESQMVTEANKAEFIDLMCQKKAIRGVEKPLEILLTSF 746
Query: 1322 SKSFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLIDI 1377
++ + L L ++L + E DW T+Y GYS ++ ++
Sbjct: 747 NQILNDNLLNSLESSDLKRILSGSLELDLNDWRTNTIYKG-----GYSDCHIVVEWFWEV 801
Query: 1378 LSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTV----VLKHPDGNISADHCLPSVMT 1433
+ + Q++ L F+TGS +P GF L+ + + K D P T
Sbjct: 802 IETMTNQERFDLLLFVTGSSSVPFEGFSALRGNEEISKFCIEKWGDAT-----SFPRAHT 856
Query: 1434 CANYLKLPKYSDKLVLKDRIAQAMTEG 1460
C N L+LP Y+ K LK ++ QA+ G
Sbjct: 857 CFNRLQLPSYNTKQQLKSKLQQAIVNG 883
>Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 748
Score = 67.0 bits (162), Expect = 2e-10
Identities = 87/384 (22%), Positives = 151/384 (38%), Gaps = 47/384 (12%)
Query: 1093 KLRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGPTL-EFYSLMSKEFARKS 1149
++ VSR+ +F + + K L I+++ EEG G E+ L+S E
Sbjct: 394 RIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPY 453
Query: 1150 LKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILD 1209
+++ + D + T + P + N + L F +G ++ ++ +D
Sbjct: 454 YGLFQYSRD------DIYTLQINPDSAV------NPEHLSYFHFVGRIMGMAVFHGHYID 501
Query: 1210 FRFNAVFF-ELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLD 1268
F F+ +L+ K D ++L D L SL ++ +N D LD
Sbjct: 502 GGFTLPFYKQLLGKSITLDDMEL------------VDPDLHNSLVWILEN---DITGVLD 546
Query: 1269 LYFMLPG------YDIELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFS 1322
F + EL G I V N +EY+ + +G++ Q A + GF+
Sbjct: 547 HTFCVEHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFN 606
Query: 1323 KSFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLIDIL 1378
+ P L EL + + + DW V T + DS I+ +
Sbjct: 607 EVIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRLKHC------TPDSNIVKWFWKAV 660
Query: 1379 SNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYL 1438
F +++ LQF+TGS ++PL GFK L+ L + + LP TC N +
Sbjct: 661 EFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRI 720
Query: 1439 KLPKYSDKLVLKDRIAQAMTEGSG 1462
+P Y L +++ A+ E G
Sbjct: 721 DIPPYESYEKLYEKLLTAIEETCG 744
>CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 810
Score = 67.0 bits (162), Expect = 2e-10
Identities = 72/293 (24%), Positives = 121/293 (40%), Gaps = 64/293 (21%)
Query: 1180 TEENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIH 1239
+E N + L F +G ++ ++ ++LD F F+++M ++ L D E+
Sbjct: 557 SEACNPEHLSYFHFIGRIIGMAIYHGKLLDAFFIRPFYKMM----LGKKITLFDMESV-- 610
Query: 1240 LVGQFDVQLGKSLAFLYDNRHDDSIKNLDLYFMLPG------YDIELLEGGSKILVESFN 1293
D + SL ++ DN D L+L F L +IEL+ G+ + V N
Sbjct: 611 -----DNEYYNSLIYVKDNDPAD----LELTFSLDDSIFGETQNIELIPNGANVPVTEDN 661
Query: 1294 VEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAV----AEDW 1349
EEY+ V P + L + EL L + +DW
Sbjct: 662 KEEYIEAVV-----------------------PSNLLRLFDANELELLMCGLQKIDVKDW 698
Query: 1350 SVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL-- 1407
T+Y GY S ++ + + +F + + LQF++G+ ++P+ GF+ L
Sbjct: 699 KANTIYKG-----GYGPSSQVVHNFWKCILSFDNEMRARVLQFVSGTSRVPMNGFRELYG 753
Query: 1408 ---KPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAM 1457
KFT+ + SAD LP TC N L LP Y+ LK ++ A+
Sbjct: 754 SNGLQKFTI-----ERWGSAD-MLPRAHTCFNRLDLPPYTTFKELKSKLLTAI 800
>7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1017
Score = 66.6 bits (161), Expect = 3e-10
Identities = 51/196 (26%), Positives = 87/196 (44%), Gaps = 22/196 (11%)
Query: 1279 ELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTEL 1338
EL GG+ I V N EY+ + +G++ Q A + GF + P L EL
Sbjct: 828 ELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPFDEREL 887
Query: 1339 SDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFIT 1394
+ G ++ DW T + ++ + ++ ++S++ + LQF+T
Sbjct: 888 ELVIGGISSIDVNDWRNNTRLKHC------TNETTQVLWFWQVVESYSSEMRARLLQFVT 941
Query: 1395 GSPKLPLGGFKNLKPK--------FTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDK 1446
GS ++PL GF+ L+ FT+ H ++ + LP TC N + LP Y
Sbjct: 942 GSSRVPLQGFRALQGSTGAVGPRLFTI---HLTADVPTQN-LPKAHTCFNRIDLPPYETY 997
Query: 1447 LVLKDRIAQAMTEGSG 1462
+L D++ QA+ E G
Sbjct: 998 QLLCDKLTQAVEETCG 1013
>At5g02880_1 [O] KOG0168 Putative ubiquitin fusion degradation protein
Length = 874
Score = 66.6 bits (161), Expect = 3e-10
Identities = 60/231 (25%), Positives = 97/231 (41%), Gaps = 11/231 (4%)
Query: 105 SRLADQRSGESGDGDVAEGEEADSERAFGRSLPDLLQELGRSEGFFGVSRGNSRYLKLIE 164
S +D+ E D + ++ DS+ R +LQ+ R S G+ LK +
Sbjct: 63 SSRSDEEEQEEQDKEDSDYGSCDSDEEDPRQR--VLQDYQRQR-----SSGDHGKLKSLL 115
Query: 165 NVLQAEDDPYIAMESLRELSEQLLMLNPLIADRIIPSGKLMDALIHVXXXXXXXXXXXXX 224
L E DP + L EL E L ++ + L L+ +
Sbjct: 116 LNLTGETDPSGQLSRLTELCEVLSFSTEESLSSVM-ANMLSPVLVKLAKHENNADIML-- 172
Query: 225 XIACRCLYNYYEMNPEMIEVSVNRDIIEILRGKLNEISYIDLAEQVLECLEFISRVHGSK 284
+A R + ++ P +E V D I L +L I Y+D+AEQ L+ LE ISR
Sbjct: 173 -LAIRAITYLCDVYPPSVEFLVRHDTIPALCQRLLTIEYLDVAEQCLQALEKISRDEPVA 231
Query: 285 ILRSGTLLSCLQYLDFFTVHAQKKSLSIVANSCARAKESDFEVVSEIFPIL 335
L +G +++ L ++DFF+ Q+ ++S V N C + + PIL
Sbjct: 232 CLNAGAIMAVLSFIDFFSTSIQRVAISTVVNICKQLSSESPSPFMDAVPIL 282
>Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 757
Score = 65.5 bits (158), Expect = 6e-10
Identities = 87/391 (22%), Positives = 152/391 (38%), Gaps = 58/391 (14%)
Query: 1093 KLRVSRDSLFLSGIKILKKYGSSP--NVLEIEYKDEEGTGLGPTL-EFYSLMSKEFARKS 1149
++ VSR+ +F + + K L ++++ EEG G E+ L+ E
Sbjct: 400 RIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPY 459
Query: 1150 LKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRILD 1209
+++ ++D Y+ + N L F +G ++ ++ ++
Sbjct: 460 YGLFQYSTDNI-----YMLQ-------INPDSSINPDHLSYFHFVGRIMGLAVFHGHYIN 507
Query: 1210 FRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNLDL 1269
F F++ + + L D E+ D +L KSL ++ +N D LD
Sbjct: 508 GGFTVPFYKQL----LGKPIQLSDLESV-------DPELHKSLVWILEN---DITPVLDH 553
Query: 1270 YFMLPGYDI------ELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSK 1323
F + EL G + V N +EY+ + +G++ Q A + GF++
Sbjct: 554 TFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNE 613
Query: 1324 SFPYSSLLILTPTELSDLFGAVAE----DWSVQTLYSSIHADHGYSMDSPIITDLIDILS 1379
P L EL + G + + DW T AD S I+ +
Sbjct: 614 LIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVAD------SNIVRWFWQAVE 667
Query: 1380 NFSTQQKRLFLQFITGSPKLPLGGFKNLKPK--------FTVVLKHPDGNISADHCLPSV 1431
F +++ LQF+TGS ++PL GFK L+ FT+ L D N LP
Sbjct: 668 TFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHL--IDANTDN---LPKA 722
Query: 1432 MTCANYLKLPKYSDKLVLKDRIAQAMTEGSG 1462
TC N + +P Y L +++ A+ E G
Sbjct: 723 HTCFNRIDIPPYESYEKLYEKLLTAVEETCG 753
>Hs4557026 [S] KOG1426 FOG: RCC1 domain
Length = 4861
Score = 65.1 bits (157), Expect = 8e-10
Identities = 73/289 (25%), Positives = 129/289 (44%), Gaps = 43/289 (14%)
Query: 1185 EKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQF 1244
++ L F+ LG L+ ++ + LD + ++ + CC L LED E V
Sbjct: 4573 DEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQL--CCVP--LTLEDLEE----VDLL 4624
Query: 1245 DVQLGKSLAFLYDNRHDDSIKNLDLYFMLP----------GYDIELLEGGSKILVESFNV 1294
VQ S+ + D I + M+P G + ++ GG+ I + N
Sbjct: 4625 YVQTLNSILHI----EDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNR 4680
Query: 1295 EEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTL 1354
+EY+ R + L + +D Q+AA R G S P L +LT +L + + E SV+ L
Sbjct: 4681 KEYVERAIEYRLHE-MDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEI-SVEVL 4738
Query: 1355 -----YSSIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKP 1409
Y + H ++ L FS +++ LF++F++G +LP ++
Sbjct: 4739 KKVVRYREVDEQH------QLVQWFWHTLEEFSNEERVLFMRFVSGRSRLP-ANTADISQ 4791
Query: 1410 KFTVV-LKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAM 1457
+F ++ + P + LP+ TC L+LP YS +LV+ +R+ A+
Sbjct: 4792 RFQIMKVDRPYDS------LPTSQTCFFQLRLPPYSSQLVMAERLRYAI 4834
>Hs4758520 [S] KOG1426 FOG: RCC1 domain
Length = 4834
Score = 63.9 bits (154), Expect = 2e-09
Identities = 60/223 (26%), Positives = 104/223 (45%), Gaps = 15/223 (6%)
Query: 1241 VGQFDVQLGKSLAFLYDNRH-DDSIKNLDLYFMLP---GYDIELLEGGSKILVESFNVEE 1296
+ + D L ++ DN + + + L F +P G DI+L + I ++ N E
Sbjct: 4572 LSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQLSSKHTHITLD--NRAE 4629
Query: 1297 YLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSVQTLYS 1356
Y +R+ + D Q+AA R G ++ P L + T EL + + D + L
Sbjct: 4630 Y-VRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCG-SPDIPLHLL-K 4686
Query: 1357 SIHADHGYSMDSPIITDLIDILSNFSTQQKRLFLQFITGSPKLP--LGGFKNLKPKFTVV 1414
S+ G + +I +++ +FS ++ LFL+F+ G +LP + F+ V+
Sbjct: 4687 SVATYKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVL 4746
Query: 1415 LKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAM 1457
K+ DH LP TC LKLP+YS K VL++++ A+
Sbjct: 4747 DKYNP----PDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAI 4785
>Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2799
Score = 62.8 bits (151), Expect = 4e-09
Identities = 71/298 (23%), Positives = 125/298 (41%), Gaps = 32/298 (10%)
Query: 1182 ENNEKTLKLFENLGTLVARSMLDNRILDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLV 1241
+N E L F N+G ++ +L N + N +++ +++ DF
Sbjct: 2520 KNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVL----LGRKVNWHDFAF----- 2570
Query: 1242 GQFDVQLGKSLAFLY----DNRHDDSIKNLDLYFMLP------GYDIELLEGGSKILVES 1291
FD + +SL L + D +DL F + G +EL+ G I V
Sbjct: 2571 --FDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTP 2628
Query: 1292 FNVEEYLIRVFDQFLGKGVDMQLAAFRNGFSKSFPYSSLLILTPTELSDLFGAVAEDWSV 1351
NV EY+ + + + + L A R G P +SL LT + L E +V
Sbjct: 2629 QNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEV-NV 2687
Query: 1352 QTL--YSSIHADHGYSMDSPIITD--LIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNL 1407
Q L ++S + + G + + + I+ S +++ + F T SP LP +
Sbjct: 2688 QMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASE-EGF 2746
Query: 1408 KPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLVLKDRIAQAMTEGSGAFL 1465
+P ++ ++ PD D LP+ TC + L +P YS K +LK ++ A+ + F+
Sbjct: 2747 QPMPSITIRPPD-----DQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV 2799
>CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2944
Score = 58.2 bits (139), Expect = 1e-07
Identities = 54/197 (27%), Positives = 90/197 (45%), Gaps = 22/197 (11%)
Query: 1278 IELLEGGSKILVESFNVEEYLIRVFDQFL-GKGVDMQLAAFRNGFSKSFPYSSLLILTPT 1336
+ L G ++LV NV EY+ + ++ L GK + + A R G P S L LTP
Sbjct: 2761 VNLKPNGDEVLVNKDNVIEYVYKYAERVLVGKRI-ITFEAIREGILDVIPESMLFGLTPE 2819
Query: 1337 ELSDLFGAVAEDWSVQTLYSSIHADHGYSMDSPIITDLID--------ILSNFSTQQKRL 1388
+L + + E S+ L + G+ +S + ++ ++ +F+ Q+K+
Sbjct: 2820 DLRLIICGI-ESVSISVLQENT----GFLDESRASQETLNRFKQWFWQVIESFTQQEKQE 2874
Query: 1389 FLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSVMTCANYLKLPKYSDKLV 1448
+ F TGSP LP G P V+ P D LP+ TC + L +P YS K V
Sbjct: 2875 LVFFWTGSPALPAAG---KWPTSASVMLRP----QEDVFLPTANTCISRLYVPVYSSKRV 2927
Query: 1449 LKDRIAQAMTEGSGAFL 1465
L+ ++ A+ + F+
Sbjct: 2928 LRTKLLLAIKAKNFGFV 2944
>At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 873
Score = 57.0 bits (136), Expect = 2e-07
Identities = 83/382 (21%), Positives = 151/382 (38%), Gaps = 54/382 (14%)
Query: 1092 HKLRVSRDSLFLSGIKILKKYGSSPNVLE----IEYKDEEGTGLGPTLEFYSLMSKEFAR 1147
H++ + R +L + + G+SP L +E+K+EE TG G E++ L+ +E
Sbjct: 511 HEMLIDRSNLLSESFEYI--VGASPEALHGGLFMEFKNEEATGPGVLREWFYLVCQEIFN 568
Query: 1148 KSLKMWKTNSDTSDDEEEYVTGALFPGPLLGTTEENNEKTLKLFENLGTLVARSMLDNRI 1207
++ ++DD + P P + + FE G ++A +++
Sbjct: 569 PKNTLFLR---SADDFRRF-----SPNPASKVDPLHPD----FFEFTGRVIALALMHKVQ 616
Query: 1208 LDFRFNAVFFELMHKCCKNDRLDLEDFETCIHLVGQFDVQLGKSLAFLYDNRHDDSIKNL 1267
+ F+ VFF + ++ LED + ++ Q+ D DS L
Sbjct: 617 VGVLFDRVFFLQL----AGLKISLEDIKDTDRIMYNSCKQI-----LEMDPEFFDSNAGL 667
Query: 1268 DLYFMLPGYD------IELLEGGSKILVESFNVEEYLIRVFDQFLGKGVDMQLAAFRNGF 1321
L F+L + IEL G V S N ++Y+ + ++ + Q+ F GF
Sbjct: 668 GLTFVLETEELGKRDTIELCPDGKLKAVNSKNRKQYVDLLIERRFATPILEQVKQFSRGF 727
Query: 1322 SKSFPYS--SLLILTPTELSDLFGAV--------AEDWSVQTLYSSIHADHGYSMDSPII 1371
+ +S L DL G + +DW T Y +G+ I
Sbjct: 728 TDMLSHSVPPRSFFKRLYLEDLDGMLRGGENPISIDDWKAHTEY------NGFKETDRQI 781
Query: 1372 TDLIDILSNFSTQQKRLFLQFITGSPKLPLGGFKNLKPKFTVVLKHPDGNISADHCLPSV 1431
IL + +++R L F T + +P+ GF+ L K + + A+ LP
Sbjct: 782 DWFWKILKKMTEEEQRSILFFWTSNKFVPVEGFRGLSSKLYIYRLY-----EANDRLPLS 836
Query: 1432 MTCANYLKLPKYSDKLVLKDRI 1453
TC L +P+Y +++ R+
Sbjct: 837 HTCFYRLCIPRYPTITLMEQRL 858
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,919,427
Number of Sequences: 60738
Number of extensions: 3132047
Number of successful extensions: 9046
Number of sequences better than 1.0e-05: 75
Number of HSP's better than 0.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 8820
Number of HSP's gapped (non-prelim): 134
length of query: 1467
length of database: 30,389,216
effective HSP length: 119
effective length of query: 1348
effective length of database: 23,161,394
effective search space: 31221559112
effective search space used: 31221559112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)