ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3468 check: MH T KOG0578 Signal transduction mechanisms p21-activated serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3468 1191592 1194558 989
(989 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 702 0.0
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 408 e-113
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 380 e-105
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 349 1e-95
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 348 2e-95
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 343 6e-94
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 335 3e-91
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 318 3e-86
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 291 3e-78
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 283 1e-75
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 279 1e-74
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 262 2e-69
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 259 1e-68
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 256 2e-67
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 247 7e-65
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 243 8e-64
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 235 2e-61
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 235 2e-61
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 202 2e-51
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 201 4e-51
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 199 2e-50
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 199 2e-50
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 197 5e-50
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 197 7e-50
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 197 7e-50
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 197 9e-50
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 197 9e-50
7300224 [T] KOG0201 Serine/threonine protein kinase 194 7e-49
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 191 4e-48
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 191 4e-48
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 191 4e-48
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 191 4e-48
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 190 1e-47
CE28674 [T] KOG0201 Serine/threonine protein kinase 189 1e-47
CE07510 [T] KOG0201 Serine/threonine protein kinase 189 1e-47
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 189 1e-47
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 185 3e-46
YHR102w [T] KOG0201 Serine/threonine protein kinase 184 5e-46
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 184 6e-46
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 184 6e-46
At3g15220 [T] KOG0201 Serine/threonine protein kinase 180 1e-44
At1g53165 [T] KOG0201 Serine/threonine protein kinase 179 2e-44
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 179 2e-44
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 178 4e-44
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 177 6e-44
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 173 1e-42
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 170 9e-42
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 170 9e-42
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 170 9e-42
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 169 3e-41
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 169 3e-41
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 169 3e-41
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 169 3e-41
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 168 3e-41
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 167 7e-41
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 166 1e-40
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 166 2e-40
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 165 3e-40
YDR523c [T] KOG0201 Serine/threonine protein kinase 165 4e-40
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 164 5e-40
7293601 [T] KOG0577 Serine/threonine protein kinase 164 5e-40
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 164 6e-40
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 164 8e-40
7293247 [T] KOG0578 p21-activated serine/threonine protein kinase 163 1e-39
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 162 2e-39
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 162 2e-39
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 162 2e-39
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 162 2e-39
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 161 4e-39
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 157 8e-38
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 153 1e-36
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 152 2e-36
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 151 4e-36
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 150 7e-36
7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 147 8e-35
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 147 1e-34
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 143 2e-33
CE01405 [T] KOG0577 Serine/threonine protein kinase 142 3e-33
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 141 4e-33
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 139 2e-32
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 139 2e-32
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 138 4e-32
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 138 5e-32
Hs22045241 [T] KOG0578 p21-activated serine/threonine protein ki... 137 1e-31
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 135 2e-31
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 135 4e-31
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 134 5e-31
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 134 9e-31
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 134 9e-31
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 133 1e-30
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 132 2e-30
Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 132 3e-30
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 132 3e-30
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 130 8e-30
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 130 1e-29
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 129 2e-29
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 129 3e-29
7300559 [T] KOG4279 Serine/threonine protein kinase 128 4e-29
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 128 5e-29
At1g70430 [T] KOG0582 Ste20-like serine/threonine protein kinase 128 5e-29
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 127 7e-29
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 127 1e-28
CE27177 [T] KOG4279 Serine/threonine protein kinase 126 1e-28
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 126 2e-28
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 125 2e-28
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 125 2e-28
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 125 2e-28
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 125 3e-28
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 124 6e-28
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 124 9e-28
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 124 9e-28
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 124 9e-28
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 124 9e-28
At4g18700 [T] KOG0583 Serine/threonine protein kinase 122 2e-27
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 122 3e-27
7300409 [T] KOG0582 Ste20-like serine/threonine protein kinase 121 5e-27
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 121 6e-27
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 119 2e-26
Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (... 119 3e-26
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 118 4e-26
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 118 5e-26
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 118 5e-26
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 118 5e-26
CE27768 [R] KOG0586 Serine/threonine protein kinase 118 5e-26
CE23838 [R] KOG0586 Serine/threonine protein kinase 118 5e-26
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 118 5e-26
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 117 7e-26
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 117 7e-26
Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 117 7e-26
Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (... 117 7e-26
At5g25110 [T] KOG0583 Serine/threonine protein kinase 117 7e-26
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 117 9e-26
At2g30360 [T] KOG0583 Serine/threonine protein kinase 116 2e-25
At5g45810 [T] KOG0583 Serine/threonine protein kinase 116 2e-25
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 116 2e-25
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 115 3e-25
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 3e-25
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 115 3e-25
At5g39440 [T] KOG0583 Serine/threonine protein kinase 115 3e-25
At2g34180 [T] KOG0583 Serine/threonine protein kinase 115 3e-25
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 114 6e-25
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 114 6e-25
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 114 7e-25
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 114 7e-25
At5g07070 [T] KOG0583 Serine/threonine protein kinase 114 7e-25
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 114 1e-24
CE23001 [R] KOG0589 Serine/threonine protein kinase 113 1e-24
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 112 2e-24
At5g45820 [T] KOG0583 Serine/threonine protein kinase 112 2e-24
At3g20860 [R] KOG0589 Serine/threonine protein kinase 112 3e-24
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 112 4e-24
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 112 4e-24
Hs20550407 [T] KOG0201 Serine/threonine protein kinase 111 5e-24
At5g58380 [T] KOG0583 Serine/threonine protein kinase 111 5e-24
7301213 [R] KOG0589 Serine/threonine protein kinase 111 5e-24
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 111 6e-24
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 110 1e-23
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 110 1e-23
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 110 1e-23
At4g30960 [T] KOG0583 Serine/threonine protein kinase 110 1e-23
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 109 2e-23
At5g10930 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 109 2e-23
7302464 [R] KOG0586 Serine/threonine protein kinase 109 2e-23
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 109 2e-23
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 109 2e-23
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 2e-23
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 109 2e-23
At5g01820 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
At5g01810 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
At4g24400 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 2e-23
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 108 3e-23
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 108 3e-23
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 108 3e-23
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 108 3e-23
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 108 4e-23
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 4e-23
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 108 4e-23
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 5e-23
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 5e-23
7299438 [R] KOG0586 Serine/threonine protein kinase 108 5e-23
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 107 7e-23
Hs21729899 [T] KOG0581 Mitogen-activated protein kinase kinase (... 107 7e-23
CE21025 [D] KOG0580 Serine/threonine protein kinase 107 7e-23
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 107 7e-23
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 107 9e-23
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 107 9e-23
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 9e-23
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 9e-23
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 107 9e-23
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 107 9e-23
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 107 1e-22
At2g38490 [T] KOG0583 Serine/threonine protein kinase 107 1e-22
7299437 [R] KOG0586 Serine/threonine protein kinase 107 1e-22
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 107 1e-22
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 107 1e-22
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 2e-22
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 2e-22
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 106 2e-22
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 106 2e-22
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 106 2e-22
At1g29230 [T] KOG0583 Serine/threonine protein kinase 106 2e-22
At1g23700 [T] KOG0582 Ste20-like serine/threonine protein kinase 106 2e-22
YKL101w [D] KOG0588 Serine/threonine protein kinase 105 3e-22
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 105 3e-22
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 105 3e-22
Hs14589900 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 105 3e-22
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 105 3e-22
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 105 3e-22
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 105 3e-22
Hs14589902 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 105 5e-22
At1g71530 [D] KOG0600 Cdc2-related protein kinase 105 5e-22
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 105 5e-22
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 104 6e-22
HsM4885147 [T] KOG0201 Serine/threonine protein kinase 104 6e-22
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 104 6e-22
Hs22035598 [T] KOG0201 Serine/threonine protein kinase 104 6e-22
At5g35410 [T] KOG0583 Serine/threonine protein kinase 104 6e-22
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 104 6e-22
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 104 6e-22
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 104 8e-22
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 104 8e-22
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 104 8e-22
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 104 8e-22
At3g29160 [T] KOG0583 Serine/threonine protein kinase 104 8e-22
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 8e-22
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 103 1e-21
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 103 1e-21
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 103 1e-21
At1g30270 [T] KOG0583 Serine/threonine protein kinase 103 1e-21
7300106 [T] KOG0690 Serine/threonine protein kinase 103 1e-21
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 103 1e-21
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 103 1e-21
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 103 1e-21
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 103 1e-21
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 1e-21
7296451 [D] KOG0600 Cdc2-related protein kinase 103 1e-21
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 103 1e-21
YCL024w [T] KOG0583 Serine/threonine protein kinase 103 2e-21
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 103 2e-21
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 103 2e-21
CE28218 [D] KOG0588 Serine/threonine protein kinase 103 2e-21
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 103 2e-21
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 103 2e-21
Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) ki... 102 2e-21
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 102 2e-21
YPL209c [D] KOG0580 Serine/threonine protein kinase 102 3e-21
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 102 3e-21
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 102 3e-21
At3g01090 [T] KOG0583 Serine/threonine protein kinase 102 3e-21
At2g25090 [T] KOG0583 Serine/threonine protein kinase 102 3e-21
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 102 3e-21
YDR507c [D] KOG0588 Serine/threonine protein kinase 102 4e-21
At4g10010 [D] KOG0600 Cdc2-related protein kinase 102 4e-21
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 4e-21
7301734 [T] KOG0694 Serine/threonine protein kinase 102 4e-21
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 102 4e-21
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 101 5e-21
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 101 5e-21
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 101 5e-21
At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GT... 101 5e-21
At2g45490 [D] KOG0580 Serine/threonine protein kinase 101 5e-21
At1g01140 [T] KOG0583 Serine/threonine protein kinase 101 5e-21
7294217 [D] KOG0588 Serine/threonine protein kinase 101 5e-21
YJL128c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 101 7e-21
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 101 7e-21
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 101 7e-21
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 100 9e-21
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 100 9e-21
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 100 9e-21
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 9e-21
At2g26980 [T] KOG0583 Serine/threonine protein kinase 100 9e-21
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 9e-21
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 100 1e-20
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 100 1e-20
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 1e-20
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 100 1e-20
At5g44290 [D] KOG0600 Cdc2-related protein kinase 100 1e-20
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 100 1e-20
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 100 1e-20
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 100 1e-20
HsM4506099 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 100 1e-20
Hs21618351 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 100 1e-20
Hs21618349 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 100 1e-20
Hs21618347 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 100 1e-20
Hs15277312 [R] KOG0584 Serine/threonine protein kinase 100 1e-20
At5g57630 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 1e-20
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 100 1e-20
At1g09600 [D] KOG0600 Cdc2-related protein kinase 100 1e-20
7302570 [R] KOG0586 Serine/threonine protein kinase 100 1e-20
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 100 2e-20
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 100 2e-20
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 100 2e-20
At3g22420 [R] KOG0584 Serine/threonine protein kinase 100 2e-20
At1g54610 [D] KOG0600 Cdc2-related protein kinase 100 2e-20
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 2e-20
YDR477w [T] KOG0583 Serine/threonine protein kinase 99 2e-20
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
CE28643 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
CE23702 [T] KOG4721 Serine/threonine protein kinase contains leu... 99 2e-20
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 99 2e-20
CE07458 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
At1g79640 [T] KOG0582 Ste20-like serine/threonine protein kinase 99 2e-20
7292829 [T] KOG0983 Mitogen-activated protein kinase (MAPK) kina... 99 2e-20
7290150 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
YLR096w [T] KOG0583 Serine/threonine protein kinase 99 3e-20
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 99 3e-20
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 99 3e-20
CE17284 [T] KOG0583 Serine/threonine protein kinase 99 3e-20
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 99 3e-20
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 99 4e-20
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 99 4e-20
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 99 4e-20
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 99 4e-20
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 99 4e-20
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 99 4e-20
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 99 4e-20
At5g39420 [D] KOG0600 Cdc2-related protein kinase 99 4e-20
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 4e-20
At1g74330 [D] KOG0600 Cdc2-related protein kinase 99 4e-20
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 98 6e-20
CE29092 [T] KOG0694 Serine/threonine protein kinase 98 6e-20
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 98 6e-20
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 98 6e-20
7299057 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 98 6e-20
7296128 [T] KOG0583 Serine/threonine protein kinase 98 6e-20
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 98 6e-20
7290147 [T] KOG0583 Serine/threonine protein kinase 98 6e-20
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 98 7e-20
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 98 7e-20
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 98 7e-20
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 98 7e-20
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 98 7e-20
Hs13376582 [T] KOG0198 MEKK and related serine/threonine protein... 98 7e-20
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 98 7e-20
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 98 7e-20
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 7e-20
At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GT... 98 7e-20
At2g24360 [T] KOG0192 Tyrosine kinase specific for activated (GT... 98 7e-20
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 7e-20
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 98 7e-20
YPL150w [T] KOG0583 Serine/threonine protein kinase 97 9e-20
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 97 9e-20
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 97 9e-20
At1g05100 [T] KOG0198 MEKK and related serine/threonine protein ... 97 9e-20
7292830 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 97 9e-20
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 97 1e-19
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 97 1e-19
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 97 1e-19
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 97 1e-19
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 97 1e-19
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 97 1e-19
CE07399 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 97 1e-19
At1g33770 [D] KOG0600 Cdc2-related protein kinase 97 1e-19
7290249 [R] KOG0586 Serine/threonine protein kinase 97 1e-19
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 97 2e-19
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 97 2e-19
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 2e-19
At1g03740 [D] KOG0600 Cdc2-related protein kinase 97 2e-19
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 96 2e-19
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 96 2e-19
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 96 2e-19
Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (... 96 2e-19
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 96 2e-19
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 96 2e-19
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 96 2e-19
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 96 2e-19
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 96 2e-19
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 96 3e-19
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 96 3e-19
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 96 3e-19
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 3e-19
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 96 3e-19
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 96 4e-19
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 4e-19
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 96 4e-19
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 4e-19
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 4e-19
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 96 4e-19
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 96 4e-19
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 96 4e-19
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 95 5e-19
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 95 5e-19
CE21239 [T] KOG0583 Serine/threonine protein kinase 95 5e-19
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 95 5e-19
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 95 5e-19
At1g48260 [T] KOG0583 Serine/threonine protein kinase 95 5e-19
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 95 6e-19
SPAC1D4.13 [T] KOG0581 Mitogen-activated protein kinase kinase (... 95 6e-19
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 95 6e-19
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 95 6e-19
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 95 6e-19
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 8e-19
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 8e-19
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 94 8e-19
CE26422 [D] KOG0600 Cdc2-related protein kinase 94 8e-19
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 94 8e-19
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 8e-19
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 94 1e-18
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 94 1e-18
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 1e-18
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 1e-18
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 1e-18
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 1e-18
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 94 1e-18
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 94 1e-18
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 94 1e-18
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 94 1e-18
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 94 1e-18
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 94 1e-18
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 94 1e-18
At5g50860 [D] KOG0600 Cdc2-related protein kinase 94 1e-18
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 1e-18
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 1e-18
At1g54510 [R] KOG0589 Serine/threonine protein kinase 94 1e-18
YDR122w [T] KOG0583 Serine/threonine protein kinase 94 1e-18
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 94 1e-18
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 94 1e-18
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 94 1e-18
CE25437 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 94 1e-18
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 94 1e-18
CE16081 [T] KOG0583 Serine/threonine protein kinase 94 1e-18
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 94 1e-18
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 1e-18
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 1e-18
At3g18750 [R] KOG0584 Serine/threonine protein kinase 94 1e-18
At1g18670 [D] KOG0600 Cdc2-related protein kinase 94 1e-18
7302860 [T] KOG0696 Serine/threonine protein kinase 94 1e-18
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 93 2e-18
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 93 2e-18
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 93 2e-18
CE02604 [T] KOG0695 Serine/threonine protein kinase 93 2e-18
CE02586 [T] KOG0696 Serine/threonine protein kinase 93 2e-18
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 93 2e-18
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 93 2e-18
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 93 2e-18
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 93 2e-18
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 93 2e-18
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 93 2e-18
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 93 2e-18
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 93 2e-18
Hs21735544 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 93 2e-18
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 93 2e-18
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 93 2e-18
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 93 2e-18
ECU05g0630 [R] KOG0584 Serine/threonine protein kinase 93 2e-18
CE27410 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
CE15235 [R] KOG0589 Serine/threonine protein kinase 93 2e-18
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 93 2e-18
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 93 2e-18
At4g32830 [D] KOG0580 Serine/threonine protein kinase 93 2e-18
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 93 2e-18
At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GT... 93 2e-18
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 93 2e-18
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 93 2e-18
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 92 3e-18
YBL105c [T] KOG0694 Serine/threonine protein kinase 92 3e-18
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 92 3e-18
CE15612 [T] KOG0690 Serine/threonine protein kinase 92 3e-18
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 3e-18
At3g17510 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 92 4e-18
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 92 4e-18
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 92 4e-18
Hs4503709 [T] KOG0200 Fibroblast/platelet-derived growth factor ... 92 4e-18
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 92 4e-18
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 92 4e-18
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 92 4e-18
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 92 4e-18
Hs13186269 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
Hs13186265 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
Hs13186263 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
Hs13186261 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
Hs13186259 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
Hs13186255 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
Hs13186253 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
Hs13186243 [T] KOG0200 Fibroblast/platelet-derived growth factor... 92 4e-18
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 92 4e-18
At2g30040 [T] KOG0198 MEKK and related serine/threonine protein ... 92 4e-18
At1g53050 [D] KOG0600 Cdc2-related protein kinase 92 4e-18
At1g49160 [R] KOG0584 Serine/threonine protein kinase 92 4e-18
Hs22055520 [R] KOG0584 Serine/threonine protein kinase 92 5e-18
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 91 7e-18
Hs21735542 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 91 7e-18
CE28479 [T] KOG0583 Serine/threonine protein kinase 91 7e-18
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 91 7e-18
CE24761 [D] KOG0580 Serine/threonine protein kinase 91 7e-18
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 702 bits (1813), Expect = 0.0
Identities = 442/931 (47%), Positives = 524/931 (55%), Gaps = 107/931 (11%)
Query: 78 LPRAPASLDVKGLQESDEDHYVKDLSDYKSMDPGKPGTVPTNVSEIFNSNQPTLDEPIQF 137
LPR +L+V LQ+ + + YKSMDP K TN + +N +LD+PIQF
Sbjct: 41 LPRTTGTLNVNALQKGTNAAH--EAGGYKSMDPAKNAET-TNDDD---NNVVSLDDPIQF 94
Query: 138 TRXXXXXXXXXXXXX----GDADLISHLEGKVEEGNNLTSKETPGTIESIVGDKTMSTIE 193
TR + D LE N TS TP D T STI
Sbjct: 95 TRVSSSSVISGMSSSMSPHSNIDETKSLEAVTPNIN--TSNITPDHS----ADNTFSTIN 148
Query: 194 GSSQNIGRISTGGRMTPDLSLMGGALETSSDFLNSTQTSNSPKITTPITEVDANDVYESP 253
S + L + +ST+T I T V S
Sbjct: 149 ASESD--------------HQFNDTLLSKLSLTDSTET-----IENNATVKHQQPVASST 189
Query: 254 LNEILSSTDSFNKASTASADHSKXXXXXXXXXXXXXXXXTTN-----EDPPIKT------ 302
+N SSTD ++ SK +N P +K
Sbjct: 190 VNSNKSSTDIRRATPVSTPVISKPSMTTTPRQINSASHSLSNPKHKQHKPKVKPSKPEAK 249
Query: 303 --PVMVNNFFENQTPVSESRSPFR-TISSPFSSLRKNVKSQHGTPDHSQRXXXXXXXXXD 359
PV V F ++ P+ S P + T S +SS K KS G+ + R
Sbjct: 250 SKPVSVKKSFPSKNPLKNSSPPKKQTEKSYYSSSSKKRKS--GSNSGTLRMKDV------ 301
Query: 360 XXXXXXXXXXXXFSTFVQNIKRNSHSEKRIXXXX---XXXXXXXAFKISTPYNAKHVYHV 416
F++FVQNIKRNS +KR A +ISTPYNAKH++HV
Sbjct: 302 ------------FTSFVQNIKRNSQDDKRASSSSNNSSSSSITTALRISTPYNAKHIHHV 349
Query: 417 GVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQDVTENSGEEKVFKTF 476
GVDSKTGEYTGLP EWEKLLTSSGIS +EQQQ+ QAVMDIVKFYQDVTE +GE+K+FKTF
Sbjct: 350 GVDSKTGEYTGLPEEWEKLLTSSGISKREQQQNMQAVMDIVKFYQDVTETNGEDKMFKTF 409
Query: 477 KVGGGSGANIASTPSFRTPSTASVQKFETPQMQTDATFPNENNDTPYSSNLQGPLLTNDF 536
G + +P TP S KF P +D+ TP S+++ P L D
Sbjct: 410 NTTTG----LPGSPQVSTPPANSFNKF--PPSTSDSHNYGSRTGTPMSNHVMSPTLNTDS 463
Query: 537 SETVNNEKFIPTRPAPKPQGSSTVSRRVEIPSPI-NSLGHGTPKVQRS-----DTQSSSI 590
S N KFIP+RPAPKP S++ S + I SP+ NS + +P Q + S +
Sbjct: 464 SSA--NGKFIPSRPAPKPPSSASASAPI-IKSPVMNSAANVSPLKQTHAPTTPNRTSPNR 520
Query: 591 FSFKKMPTLKSE-QPLPPIPKAAEKXXXXXXXXXXXXXXXXXXXXXXEQS-----SIPAI 644
S + TLK E QPLPPIP K +++ S PA
Sbjct: 521 SSISRNATLKKEEQPLPPIPPTKSKTSPIISTAHTPQQVAQSPKAPAQETVTTPTSKPAQ 580
Query: 645 PSGLAVEVKEESNTSNVXXXXXXXXXXXXXXXXXXXXXSKLTEICTTGDPSKLYKNLIKI 704
L+ E+ E+ +KL EIC+ GDPS Y NL+KI
Sbjct: 581 ARSLSKELNEKKREER--------------ERRKKQLYAKLNEICSDGDPSTKYANLVKI 626
Query: 705 GQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYLF 764
GQGASGGVYTAYE+GTN SVAIKQMNLEKQPKKELI+NEILVMKGSKH NIVNFIDSY+
Sbjct: 627 GQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVL 686
Query: 765 RGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNIL 824
+GDLWV+MEYMEGGSLTDVVTHCILTEGQIGAV RETL GL+FLHSKGV+HRDIKSDNIL
Sbjct: 687 KGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNIL 746
Query: 825 LSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXXXX 884
LSM GDIKLTDFGFCAQINE+NLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL
Sbjct: 747 LSMEGDIKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIE 806
Query: 885 XXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLL 944
PPYLNETPLRALYLIATNGTPKLK+P NLS + FL+WCL V+PEDR +A +LL
Sbjct: 807 MIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELL 866
Query: 945 EDPFITEIAEENTSLAPLVKLARMKKLAESM 975
D +ITEIAE N+SLAPLVKLAR+KK+AE+M
Sbjct: 867 HDEYITEIAEANSSLAPLVKLARLKKVAENM 897
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 408 bits (1048), Expect = e-113
Identities = 245/570 (42%), Positives = 318/570 (54%), Gaps = 74/570 (12%)
Query: 404 ISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQDV 463
IS+P++ KHV HVG + TGE+TG+P EW+ LL SGI+ EQ QHPQAV+D + FY
Sbjct: 147 ISSPFDPKHVTHVGFNYDTGEFTGMPTEWQALLKVSGITKSEQVQHPQAVLDAMAFYSQS 206
Query: 464 TENSGEEKVFKTFKVGGGSGANIASTPSFRTPSTASVQKFETPQMQTDATFPNENNDTPY 523
+ E + P F ST E P + A
Sbjct: 207 KKYLEE-----------------GAKPPFPREST------EKPLLSVSALSS-------- 235
Query: 524 SSNLQGPLLTNDFSETVNNEKFIPTRPAPKPQGSSTVSRRVEIPSPINSLGHGTPKVQRS 583
SS+LQ S T ++ + P+RPAP P SS+ SP+ S +
Sbjct: 236 SSHLQPT------SATSSSSRLYPSRPAPTPPASSS-------SSPLLSSQTVKTTTSNA 282
Query: 584 DTQSSSIFSFKKMPTL-KSEQPLPPIPKAAEKXXXXXXXXXXXXXXXXXXXXXXEQSSI- 641
Q S + S K + +S P+ P+ + ++
Sbjct: 283 SRQPSPLVSSKSTDNIIRSHSPVLLTPQTLSTSETKHIRPNNSTPYQRRAETSTKPKAVA 342
Query: 642 -------PAIPSGLAVEVKEESNTSNVXXXXXXXXXXXXXXXXXXXXXSKLTEICTTGDP 694
P+ P +++SN S V +KL IC +P
Sbjct: 343 TPQKVEAPSAPRLQKRAPRQQSNDSAVL--------------------AKLQSICNPKNP 382
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNN 754
+ LY+N +KIGQGASG VY+A ++GTN SVAIK+MN+ +QPKKE IVNEILVMK H N
Sbjct: 383 TLLYRNFVKIGQGASGDVYSARQVGTNLSVAIKKMNINQQPKKEFIVNEILVMKSHHHKN 442
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
IVNFID++ ++ +LW+VMEYM GGSLT+VVT+ L+EGQI A+ +ETL+GLQ LH G++
Sbjct: 443 IVNFIDTFFYKSELWMVMEYMRGGSLTEVVTNNTLSEGQIAAICKETLEGLQHLHENGIV 502
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
HRDIKSDNILLS+ GDIKLTDFGFCAQI+ KRTTMVGTPYWMAPEVV+RKEYG KVD
Sbjct: 503 HRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFKVD 562
Query: 875 IWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDP 934
+WSL PPYLNE PLRALYLIAT GTPK+ P LS FL+ L V+P
Sbjct: 563 VWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPELLSSVFHDFLSKSLTVNP 622
Query: 935 EDRGTAADLLEDPFITEIAEENTSLAPLVK 964
+ R ++ +LL PF+ + A +SL PL+K
Sbjct: 623 KQRPSSGELLRHPFLKQ-AVPVSSLIPLIK 651
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 380 bits (975), Expect = e-105
Identities = 237/572 (41%), Positives = 314/572 (54%), Gaps = 70/572 (12%)
Query: 404 ISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQDV 463
IS P N +H HVG D KTGE+TG+P W +LLT S IS +EQQQ+PQAV+D +K+Y
Sbjct: 67 ISRPSNFEHTIHVGYDPKTGEFTGMPEAWARLLTDSQISKQEQQQNPQAVLDALKYYTQ- 125
Query: 464 TENSGEEKVFKTFKVGGGSGANIASTPSFRTPSTASVQKFETPQMQTDATFPNENNDTPY 523
E+SG++ + I PS RTPS PQ + ++ P N
Sbjct: 126 GESSGQKWLQYDMMF-------IDDAPS-RTPSYGL-----KPQPYSTSSLPYHGNKIQD 172
Query: 524 SSNLQGPLLTNDFSETVNNEKFIPTRPAPKPQGSSTVSRRVEIPSPINSLGHGTPKVQRS 583
+ P+ T+ S N+++ +P P S R +P + P V
Sbjct: 173 PRKMN-PMTTSTSSAGYNSKQGVP------PTTFSVNENRSSMPP-----SYAPPPVPHG 220
Query: 584 DTQSSSIFSFKKMPTLKSEQPLPPIPKAAEKXXXXXXXXXXXXXXXXXXXXXXEQSSIPA 643
+T + + P IP + E+ IP
Sbjct: 221 ETPADIV--------------PPAIPDRPARTLSIYTKPKE------------EEEKIPD 254
Query: 644 IPSG-LAVEVKEESNTSNVXXXXXXXXXXXXXXXXXXXXXSKLTEICTTGDPSKLYKNLI 702
+ G V+ + + + +KL I + G+P + Y+ +
Sbjct: 255 LSKGQFGVQARGQKAKKKMTDAEVL---------------TKLRTIVSIGNPDRKYRKVD 299
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSY 762
KIG GASG VYTA E+ T A VAIKQMNL+ QPKKELI+NEILVM+ +KH NIVN++DSY
Sbjct: 300 KIGSGASGSVYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMRENKHANIVNYLDSY 359
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDN 822
L +LWVVMEY+ GGSLTDVVT C + +G I AV RE L+ L+FLHS+ VIHRDIKSDN
Sbjct: 360 LVCDELWVVMEYLAGGSLTDVVTECQMEDGIIAAVCREVLQALEFLHSRHVIHRDIKSDN 419
Query: 823 ILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXX 882
ILL M+G +KLTDFGFCAQ++ KRTTMVGTPYWMAPEVV+RK+YGPKVD+WSL
Sbjct: 420 ILLGMDGSVKLTDFGFCAQLSPEQRKRTTMVGTPYWMAPEVVTRKQYGPKVDVWSLGIMA 479
Query: 883 XXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAAD 942
PPYLNE PLRA+YLIATNG P +++ F++ L V E+R +A+
Sbjct: 480 IEMVEGEPPYLNENPLRAIYLIATNGKPDFPGRDSMTLLFKDFVDSALEVQVENRWSASQ 539
Query: 943 LLEDPFITEIAEENTSLAPLVKLARMKKLAES 974
LL PF+ A+ SL L+ +A K +AE+
Sbjct: 540 LLTHPFL-RCAKPLASLYYLI-VAAKKSIAEA 569
>Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 544
Score = 349 bits (895), Expect = 1e-95
Identities = 178/284 (62%), Positives = 212/284 (73%), Gaps = 1/284 (0%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL I + GDP K Y KIGQGASG VYTA ++ T VAIKQMNL++QPKKELI+NE
Sbjct: 254 KLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINE 313
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLK 803
ILVM+ +K+ NIVN++DSYL +LWVVMEY+ GGSLTDVVT + EGQI AV RE L+
Sbjct: 314 ILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQ 373
Query: 804 GLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV 863
L FLHS VIHRDIKSDNILL M+G +KLTDFGFCAQI KR+TMVGTPYWMAPEV
Sbjct: 374 ALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 433
Query: 864 VSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMA 923
V+RK YGPKVDIWSL PPYLNE PLRALYLIATNGTP+L++P LS
Sbjct: 434 VTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFR 493
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
FLN CL +D + RG+A +LL+ PF+ ++A+ +SL PL+ A+
Sbjct: 494 DFLNRCLEMDVDRRGSAKELLQHPFL-KLAKPLSSLTPLIIAAK 536
Score = 75.1 bits (183), Expect = 5e-13
Identities = 45/119 (37%), Positives = 68/119 (56%), Gaps = 5/119 (4%)
Query: 403 KISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQD 462
+IS P + +H HVG D+ TGE+TG+P +W +LL +S I+ EQ+++PQAV+D++KFY D
Sbjct: 69 EISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY-D 127
Query: 463 VTENSGEEKVFKTFKVGGGSG-ANIASTPSFRTPSTASVQKFETPQMQTDATFPNENND 520
E +K + +F G S IA+ PS + TAS P + + E D
Sbjct: 128 SKETVNNQK-YMSFTSGDKSAHGYIAAHPS--STKTASEPPLAPPVSEEEDEEEEEEED 183
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 348 bits (894), Expect = 2e-95
Identities = 179/284 (63%), Positives = 212/284 (74%), Gaps = 1/284 (0%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL I + GDP K Y KIGQGASG VYTA ++ T VAIKQMNL++QPKKELI+NE
Sbjct: 256 KLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINE 315
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLK 803
ILVM+ +K+ NIVN++DSYL +LWVVMEY+ GGSLTDVVT + EGQI AV RE L+
Sbjct: 316 ILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQ 375
Query: 804 GLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV 863
L+FLHS VIHRDIKSDNILL M+G +KLTDFGFCAQI KR+TMVGTPYWMAPEV
Sbjct: 376 ALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV 435
Query: 864 VSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMA 923
V+RK YGPKVDIWSL PPYLNE PLRALYLIATNGTP+L++P LS
Sbjct: 436 VTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFR 495
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
FLN CL +D E RG+A +LL+ F+ +IA+ +SL PL+ A+
Sbjct: 496 DFLNRCLDMDVEKRGSAKELLQHQFL-KIAKPLSSLTPLIAAAK 538
Score = 73.2 bits (178), Expect = 2e-12
Identities = 50/156 (32%), Positives = 80/156 (51%), Gaps = 17/156 (10%)
Query: 403 KISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQD 462
+IS P + +H HVG D+ TGE+TG+P +W +LL +S I+ EQ+++PQAV+D+++FY
Sbjct: 74 EISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNS 133
Query: 463 -VTENSGEEKVFKTFKVGGGSGANIASTPSF-RTPSTASVQKFETPQMQTDATFP----- 515
T NS + F + +N + + TP+ V + E DAT P
Sbjct: 134 KKTSNSQKYMSFTDKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDD-DDDATPPPVIAP 192
Query: 516 -NENNDTPYSSNLQGPL--------LTNDFSETVNN 542
E+ + Y+ ++ PL T+ S T NN
Sbjct: 193 RPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENN 228
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 343 bits (881), Expect = 6e-94
Identities = 172/284 (60%), Positives = 210/284 (73%), Gaps = 1/284 (0%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL I + GDP++ Y + KIGQGASG VYTA E T VAIKQMNL +QPKKELI+NE
Sbjct: 416 KLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINE 475
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLK 803
ILVM+ +KH N+VN++DSYL +LWVVMEY+ GGSLTDVVT + EGQI AV RE L+
Sbjct: 476 ILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQ 535
Query: 804 GLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV 863
L+FLH+ VIHRDIKSDNILL ++G +KLTDFGFCAQI+ KRTTMVGTPYWMAPEV
Sbjct: 536 ALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEV 595
Query: 864 VSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMA 923
V+RK+YGPKVD+WSL PPYLNE PL+ALYLIATNG P++K+ LS
Sbjct: 596 VTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQ 655
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
FL+ CL V+ + R +A DLL+ PF+ ++A SL PL+ A+
Sbjct: 656 DFLDQCLEVEVDRRASALDLLKHPFL-KLARPLASLTPLIMAAK 698
Score = 78.2 bits (191), Expect = 6e-14
Identities = 59/218 (27%), Positives = 100/218 (45%), Gaps = 20/218 (9%)
Query: 404 ISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQDV 463
IS P N +H HVG D+ TGE+TG+P W +LL +S IS +EQ+++PQAV+D++K++ +
Sbjct: 83 ISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQEQKKNPQAVLDVLKWFDNT 142
Query: 464 TENSGEEKVFKTFKVGGGSGANIASTPSFRTPSTASVQKFETP---------QMQTDATF 514
T+ K + T + SG++++ S ST + + Q+ +
Sbjct: 143 TKQRPSSK-YMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGVQLGSMTLG 201
Query: 515 PNENNDTPYSSNLQGPLLTNDFSETVNNEKFIPTRPAPKPQGSSTVSRRVEIPSPINSLG 574
PN NN + G +L N + + + + + Q + + N +G
Sbjct: 202 PNANNVA-----VAGQILGNHYQQ--QQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVG 254
Query: 575 HGTPKVQRSDTQSSSIFSFKKMPTLKSEQPLPPIPKAA 612
H V S +Q SS + +Q PP P A+
Sbjct: 255 H---TVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVAS 289
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 335 bits (858), Expect = 3e-91
Identities = 175/285 (61%), Positives = 209/285 (72%), Gaps = 2/285 (0%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL I + GDP K Y KIGQGASG V+TA ++ VAIKQ+NL+KQPKKELI+NE
Sbjct: 235 KLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINE 294
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTH-CILTEGQIGAVSRETL 802
ILVMK K+ NIVNF+DSYL +L+VVMEY+ GGSLTDVVT + E QI AV RE L
Sbjct: 295 ILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETACMDEAQIAAVCRECL 354
Query: 803 KGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPE 862
+ L+FLH+ VIHRDIKSDN+LL M G +KLTDFGFCAQI KR+TMVGTPYWMAPE
Sbjct: 355 QALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE 414
Query: 863 VVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKM 922
VV+RK YGPKVDIWSL PPYLNE PLRALYLIATNGTP+L++P LS
Sbjct: 415 VVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIF 474
Query: 923 AMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
FLN CL +D E RG+A +LL+ PF+ ++A+ +SL PL+ A+
Sbjct: 475 RDFLNRCLEMDVEKRGSAKELLQHPFL-KLAKPLSSLTPLIMAAK 518
Score = 73.6 bits (179), Expect = 1e-12
Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 19/158 (12%)
Query: 403 KISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQD 462
+IS P + +H HVG D+ TGE+TG+P +W +LL +S I+ EQ+++PQAV+D++KFY
Sbjct: 73 EISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDS 132
Query: 463 VTENSGEEKVFKTFKVGGGSGANIASTPSFRTPSTASVQKFETPQMQTDATFPNENNDTP 522
T K G SG TP+ T E P + T+ E++D
Sbjct: 133 NTVKQKYLSFTPPEKDGLPSG-----TPALNAKGT------EAPAVVTE----EEDDDEE 177
Query: 523 YSSNLQGPLLTNDFSETVNNEKFIPTRPAPKPQGSSTV 560
+ + P D ++++ I P P P G S V
Sbjct: 178 TAPPVIAP--RPDHTKSIYTRSVID--PVPAPVGDSHV 211
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 318 bits (814), Expect = 3e-86
Identities = 203/570 (35%), Positives = 294/570 (50%), Gaps = 31/570 (5%)
Query: 403 KISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQD 462
+I P N + +HV + +TG+ GLP W +L+ S I+ EQ ++P A VK+Y +
Sbjct: 19 EIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLMNSQ-ITRDEQDKNPDAAYHAVKYY-N 76
Query: 463 VTENSGEEKVFKTF---KVGGGSGANIASTPSFRTPSTASVQKFETPQMQTDATFPNENN 519
+ E +VFK F V I + +++ K + P+ ++D +
Sbjct: 77 YSIKKKENEVFKPFITEDVIHEESKEIENYVNYKNK-----HKSQDPE-KSDDDGSSTAT 130
Query: 520 DTPYSSNLQGPLLTNDFSETVNNEKFIPTRPAPKPQGSSTVSRRVEIPSPINSLGHGTPK 579
+T SS G N S ++N+ T P + E+ + +
Sbjct: 131 ETESSSGC-GSSAGNSNSSSINDSSQQSTVPLDALE---------EVFKELKT------N 174
Query: 580 VQRSDTQSSSIFSFKKMPTLKSEQPLPPIPKAAEKXXXXXXXXXXXXXXXXXXXXXXEQS 639
++ +T ++ +P KS +PP P+ K +
Sbjct: 175 LEHRETLKAAPQEPPPVPPKKSPHTIPPKPQIKPKPRVTQKFSRTSDIRRDEDSDNQHKI 234
Query: 640 SIPAIPSGLAVEVKEESNTSNVXXXXXXXXXXXXXXXXXXXXXSKLTEICTTGDPSKLYK 699
+ I AV ++ N +L IC + DP + YK
Sbjct: 235 NTDTIIIKPAVGAQDAGADDNPDETILRRSKEKRAQKTDAEIYVELRAICNSDDPRERYK 294
Query: 700 NLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFI 759
++G+GASG V+ A +L + VA+K ++++ Q K+LI+ EI V+K H N+VNF+
Sbjct: 295 TTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFL 354
Query: 760 DSYLFRGD--LWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
D+YL + LWVVMEYM+GG LTDVVT ++ E QI V RETL + FLH+KG+IHRD
Sbjct: 355 DAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRD 414
Query: 818 IKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWS 877
IKSDN+LL M+G +K+TDFGFCA I E + KR TMVGTPYWMAPEVV+RK+YG KVDIWS
Sbjct: 415 IKSDNVLLGMDGSVKVTDFGFCANI-EGDEKRQTMVGTPYWMAPEVVTRKKYGKKVDIWS 473
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
+ PPYL ETPLRALYLIA NG P +K LS + FL+ CL V+ + R
Sbjct: 474 IGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRR 533
Query: 938 GTAADLLEDPFITEIAEENTSLAPLVKLAR 967
TA +LL PF+ + +E +L P +K A+
Sbjct: 534 ATADELLSHPFLNDCSEVK-ALVPNIKAAK 562
>YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 842
Score = 291 bits (745), Expect = 3e-78
Identities = 158/294 (53%), Positives = 193/294 (64%), Gaps = 28/294 (9%)
Query: 683 SKLTEICTTGDPSKLYKNLIKIGQGASGGVYTA-----------YELGTNA--------S 723
SKL ++ DPS+ +K + K GQGASG VY A EL N
Sbjct: 531 SKLKKVTVNADPSQCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDK 590
Query: 724 VAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYLFRGD-LWVVMEYMEGGSLTD 782
VAIKQM L KQP+KELIVNEILVMK S+H NIVNF+++YL D LWVVME+MEGGSLTD
Sbjct: 591 VAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTD 650
Query: 783 VV--------THCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLT 834
++ +H LTE QI + RET +GL+FLH K +IHRDIKSDN+LL +K+T
Sbjct: 651 IIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKIT 710
Query: 835 DFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLN 894
DFGFCA++ + KR TMVGTPYWMAPEVV ++EY K+D+WSL PPYLN
Sbjct: 711 DFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLN 770
Query: 895 ETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPF 948
E PL+ALYLIATNGTPKLK P +LS ++ FL+ CL VD R + +LL F
Sbjct: 771 EDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGF 824
Score = 62.0 bits (149), Expect = 4e-09
Identities = 46/169 (27%), Positives = 74/169 (43%), Gaps = 30/169 (17%)
Query: 404 ISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQDV 463
+S+P N H HVG D +TG + G+P WEKLL S I+ ++ + AV+ +++FYQ+
Sbjct: 184 VSSPTNFTHKVHVGFDPETGSFVGMPTNWEKLLKHSRITGEDWNNNSAAVIQVLQFYQEY 243
Query: 464 TENSGEEKVFKTFKVGGGSGANIASTPSFRTPSTASVQKFETPQMQTDATFPNENNDTPY 523
G G+ N P ++ T+S QK + PN ND
Sbjct: 244 N--------------GAGNPTNTLDKP--QSGETSSSQK----------SLPNSYND--- 274
Query: 524 SSNLQGPLLTNDFSETVNNEKFIPTRPAPKPQGSSTVSRRVEIPSPINS 572
+ L+ + + S V++ + + P S VS PIN+
Sbjct: 275 -NKLRNNSVNSKSSSGVSSSMVSQRKTSQPPNTKSPVSLGSGSLPPINT 322
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 283 bits (723), Expect = 1e-75
Identities = 146/288 (50%), Positives = 195/288 (67%), Gaps = 3/288 (1%)
Query: 683 SKLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN 742
++L EI +P Y+ +IG GASG V+ A G+ VA+K+M + QPKKE+++
Sbjct: 93 NQLREIVNPSNPLGKYEMKKQIGVGASGTVFVANVAGSTDVVAVKRMAFKTQPKKEMLLT 152
Query: 743 EILVMKGSKHNNIVNFIDSYLFRGD-LWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRET 801
EI VMK +H N+VN+I+SYL D LWVVM+Y+EGG+LTDVV L EGQI AV +E
Sbjct: 153 EIKVMKQYRHPNLVNYIESYLVDADDLWVVMDYLEGGNLTDVVVKTELDEGQIAAVLQEC 212
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LK L FLH ++HRDIKSDN+LL MNG++KLTD GFCAQI + KR T+VGTPYWM+P
Sbjct: 213 LKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQI-QPGSKRDTVVGTPYWMSP 271
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
E++++K+Y KVDIWSL PPYL ETPL+A+YLIA NG P++K LS +
Sbjct: 272 EILNKKQYNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSE 331
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMK 969
FL+ CL+VDP+ R +LL PF+ + A+ +SL P ++ R K
Sbjct: 332 FNNFLDKCLVVDPDQRADTTELLAHPFLKK-AKPLSSLIPYIRAVREK 378
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 279 bits (714), Expect = 1e-74
Identities = 147/273 (53%), Positives = 184/273 (66%), Gaps = 6/273 (2%)
Query: 685 LTEICTTGDPSKLYKNLIKIGQGASGGVYTAY-----ELGTNASVAIKQMNLEKQPKKEL 739
L + T+ DP + + K+GQGASG VY A +LG SVAIK ++L+ Q +KEL
Sbjct: 296 LKDSVTSHDPVEYFNVKHKLGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTRKEL 355
Query: 740 IVNEILVMKGSKHNNIVNFIDSYLFRG-DLWVVMEYMEGGSLTDVVTHCILTEGQIGAVS 798
I+NEI VM+ S H NIV ++DS+L R LWVVMEYM GSLTD++ LTE QI +
Sbjct: 356 ILNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARIC 415
Query: 799 RETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYW 858
ET KG+Q LH++ +IHRDIKSDN+LL +G+IK+TDFGFCA+++ KR TMVGTPYW
Sbjct: 416 LETCKGIQHLHARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVTMVGTPYW 475
Query: 859 MAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNL 918
MAPEVV + EYG KVDIWSL PPYL E P+RALYLIA NGTP LK P +
Sbjct: 476 MAPEVVKQNEYGTKVDIWSLGIMIIEMIENEPPYLREDPIRALYLIAKNGTPTLKKPNLV 535
Query: 919 SHKMAMFLNWCLMVDPEDRGTAADLLEDPFITE 951
S + FLN CL +D R TAA+LL F+ +
Sbjct: 536 SKNLKSFLNSCLTIDTIFRATAAELLTHSFLNQ 568
Score = 64.3 bits (155), Expect = 9e-10
Identities = 31/71 (43%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
Query: 401 AFKISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFY 460
A K+S+P N KH HVG+D++ G Y GLP EW LL SS I+ +E + P+AV+ + FY
Sbjct: 126 ASKVSSPMNPKHQVHVGIDNE-GNYVGLPKEWILLLQSSSITKQECMEEPKAVIQALDFY 184
Query: 461 QDVTENSGEEK 471
+ + E K
Sbjct: 185 SKQLDTTSETK 195
>Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 591
Score = 262 bits (669), Expect = 2e-69
Identities = 131/278 (47%), Positives = 188/278 (67%), Gaps = 1/278 (0%)
Query: 692 GDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSK 751
GDP N IKIG+G++G V A + VA+K+M+L KQ ++EL+ NE+++M+ +
Sbjct: 315 GDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQ 374
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
H N+V +SYL +LWVVME++EGG+LTD+VTH + E QI AV L+ L LH++
Sbjct: 375 HENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQ 434
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
GVIHRDIKSD+ILL+ +G +KL+DFGFCAQ+++ +R ++VGTPYWMAPE++SR YGP
Sbjct: 435 GVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGP 494
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
+VDIWSL PPY NE PL+A+ +I N P+LK+ +S + FL+ L+
Sbjct: 495 EVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLV 554
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMK 969
DP R TAA+LL+ PF+ + A S+ PL++ R +
Sbjct: 555 RDPAQRATAAELLKHPFLAK-AGPPASIVPLMRQNRTR 591
>Hs14771959 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 719
Score = 259 bits (662), Expect = 1e-68
Identities = 130/280 (46%), Positives = 188/280 (66%), Gaps = 1/280 (0%)
Query: 688 ICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVM 747
+ + GDP + N IKIG+G++G V A E T VA+K+M+L KQ ++EL+ NE+++M
Sbjct: 439 VVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIM 498
Query: 748 KGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQF 807
+ H+N+V+ SYL +LWVVME++EGG+LTD+VTH + E QI V L+ L +
Sbjct: 499 RDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSY 558
Query: 808 LHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRK 867
LH++GVIHRDIKSD+ILL+ +G IKL+DFGFCAQ+++ KR ++VGTPYWMAPEV+SR
Sbjct: 559 LHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRL 618
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLN 927
YG +VDIWSL PPY NE PL+A+ I + P++KD +S + FL+
Sbjct: 619 PYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLD 678
Query: 928 WCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
L+ +P R TA +LL PF+ ++A + + PL++ R
Sbjct: 679 LMLVREPSQRATAQELLGHPFL-KLAGPPSCIVPLMRQYR 717
>YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 655
Score = 256 bits (653), Expect = 2e-67
Identities = 134/295 (45%), Positives = 183/295 (61%), Gaps = 28/295 (9%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELG-----------------TNASVAI 726
K+ + +P ++ + K GQGASG VY + + VAI
Sbjct: 346 KMKTVAIDVNPRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAI 405
Query: 727 KQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYLFRGD-LWVVMEYMEGGSLTDVVT 785
KQ+ L +QPKK+LI+NE+LVM S+ NIVNF+++Y+ + LWV+MEYMEGG LTD++
Sbjct: 406 KQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILD 465
Query: 786 HCI----------LTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTD 835
L E Q+ + +ET +GL+FLH+K +IHRDIKSDNILL+ G +K+TD
Sbjct: 466 AVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITD 525
Query: 836 FGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNE 895
FGFC ++ E KR TMVGTPYWMAPE+V++K Y KVD+WSL PPYLNE
Sbjct: 526 FGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNE 585
Query: 896 TPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFIT 950
PL+ALYLIA NG+PKL+ P ++S + FL+ CL V+ E R + LL F++
Sbjct: 586 DPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLS 640
Score = 55.5 bits (132), Expect = 4e-07
Identities = 23/59 (38%), Positives = 38/59 (63%)
Query: 404 ISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLLTSSGISMKEQQQHPQAVMDIVKFYQD 462
+S+P N H HVG D K G + G+P+ W KLL +S I+ + ++ +AV+ ++FY+D
Sbjct: 123 VSSPTNFTHKVHVGFDPKVGNFVGVPDSWAKLLQTSEITYDDWNRNSKAVIKALQFYED 181
>Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 681
Score = 247 bits (630), Expect = 7e-65
Identities = 124/283 (43%), Positives = 186/283 (64%), Gaps = 1/283 (0%)
Query: 685 LTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEI 744
L + GDP L + +KIG+G++G V A E + VA+K M+L KQ ++EL+ NE+
Sbjct: 394 LRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEV 453
Query: 745 LVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKG 804
++M+ +H N+V SYL +LWV+ME+++GG+LTD+V+ L E QI V L+
Sbjct: 454 VIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQA 513
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV 864
L +LH++GVIHRDIKSD+ILL+++G +KL+DFGFCAQI++ KR ++VGTPYWMAPEV+
Sbjct: 514 LAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI 573
Query: 865 SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAM 924
SR Y +VDIWSL PPY +++P++A+ + + PKLK+ +S +
Sbjct: 574 SRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRD 633
Query: 925 FLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
FL L+ DP++R TA +LL+ PF+ + L PL++L R
Sbjct: 634 FLERMLVRDPQERATAQELLDHPFLLQTGLPE-CLVPLIQLYR 675
>Hs18602554 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 227
Score = 243 bits (621), Expect = 8e-64
Identities = 126/221 (57%), Positives = 158/221 (71%), Gaps = 1/221 (0%)
Query: 747 MKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQ 806
MK K+ NIVNF+DSYL +L+VV+EY+ GSLTDVVT + E QI AV RE+L+ L+
Sbjct: 1 MKELKNPNIVNFLDSYLVGDELFVVVEYLARGSLTDVVTETCMDEAQIAAVCRESLQALE 60
Query: 807 FLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR 866
FLH+ VIHRDIKSD++LL M G +KLTDFGFCAQI KR+T+V TPYWMAPEVV+R
Sbjct: 61 FLHANQVIHRDIKSDSVLLGMEGSVKLTDFGFCAQITPEQSKRSTVVRTPYWMAPEVVTR 120
Query: 867 KEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
K YGPKV++WSL PPYLNE PLRAL LIATNG P+L++P LS FL
Sbjct: 121 KAYGPKVNVWSLGIMATEMVEGEPPYLNENPLRALCLIATNGIPELQNPETLSPIFRDFL 180
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
N CL D E RG+A +LL+ F+ ++A+ +SL PL+ A+
Sbjct: 181 NRCLETDVEKRGSAKELLQHLFL-KLAKLLSSLTPLIMAAK 220
>CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 540
Score = 235 bits (600), Expect = 2e-61
Identities = 117/271 (43%), Positives = 173/271 (63%), Gaps = 1/271 (0%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP + +IG+G++G V AY++ T VA+K+MNL KQ ++EL+ NE+ +++ +H
Sbjct: 244 DPRSDLTDYKQIGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRRELLFNEVSILRQYQH 303
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKG 812
NIV F S+L +LWVVME+MEGGSLTD+VT +TE QI +SR+ L L FLH++
Sbjct: 304 PNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHARK 363
Query: 813 VIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPK 872
VIHRDIKSD+ILL +G +KLTDFGFC Q++E +R ++VGTPYW A EV++R+ Y +
Sbjct: 364 VIHRDIKSDSILLKRDGTVKLTDFGFCGQLSEEVPRRRSLVGTPYWTAAEVIAREPYDTR 423
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMV 932
DIWS PP+ N+ P +A+ I + +S +++ L+ C++
Sbjct: 424 ADIWSFGIMLIEMVEGEPPFFNDQPFQAMKRIRDEHEARFSRHAKVSVELSELLSHCIVK 483
Query: 933 DPEDRGTAADLLEDPFITEIAEENTSLAPLV 963
D R A DLL PF + A+ ++S+APL+
Sbjct: 484 DVNKRWPAKDLLRHPFFAK-AQHSSSIAPLL 513
Score = 51.2 bits (121), Expect = 8e-06
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Query: 383 SHSEKRIXXXXXXXXXXXAFKISTPYNAKHVYHVGVDSKTGEYTGLPNEWEKLL-TSSGI 441
S++EK++ +ISTP N +H H G D+++G YTGLP +W+ LL I
Sbjct: 15 SYAEKKMNRTFSLRRKVKKSEISTPSNFEHRIHAGFDARSGTYTGLPKQWQALLGPPRSI 74
Query: 442 SMKEQQQHPQAV--MDIVKFYQDVTENSGEEKVFKTFKVGGGSGANIASTPSFRTPSTAS 499
S + P + +D+ + + S F + ++A + S R +TAS
Sbjct: 75 SRPKPMVDPSCITPVDVAELKTVIRGPSSRYNSPLPFGMTNSPMPSVARSNSLRISATAS 134
>CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 542
Score = 235 bits (600), Expect = 2e-61
Identities = 117/271 (43%), Positives = 173/271 (63%), Gaps = 1/271 (0%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP + +IG+G++G V AY++ T VA+K+MNL KQ ++EL+ NE+ +++ +H
Sbjct: 246 DPRSDLTDYKQIGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRRELLFNEVSILRQYQH 305
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKG 812
NIV F S+L +LWVVME+MEGGSLTD+VT +TE QI +SR+ L L FLH++
Sbjct: 306 PNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHARK 365
Query: 813 VIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPK 872
VIHRDIKSD+ILL +G +KLTDFGFC Q++E +R ++VGTPYW A EV++R+ Y +
Sbjct: 366 VIHRDIKSDSILLKRDGTVKLTDFGFCGQLSEEVPRRRSLVGTPYWTAAEVIAREPYDTR 425
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMV 932
DIWS PP+ N+ P +A+ I + +S +++ L+ C++
Sbjct: 426 ADIWSFGIMLIEMVEGEPPFFNDQPFQAMKRIRDEHEARFSRHAKVSVELSELLSHCIVK 485
Query: 933 DPEDRGTAADLLEDPFITEIAEENTSLAPLV 963
D R A DLL PF + A+ ++S+APL+
Sbjct: 486 DVNKRWPAKDLLRHPFFAK-AQHSSSIAPLL 515
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 202 bits (515), Expect = 2e-51
Identities = 107/268 (39%), Positives = 152/268 (55%), Gaps = 4/268 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL E T P +++ L K+G+G+ G VY A T VAIKQ+ +E ++ I+ E
Sbjct: 16 KLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE--IIKE 73
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ ++V + SY DLW+VMEY GS++D++ + LTE +I + + T
Sbjct: 74 ISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQST 133
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LKGL++LH IHRDIK+ NILL+ G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 134 LKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 193
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y DIWSL PPY + P+RA+++I TN P + P S
Sbjct: 194 EVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDN 253
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFI 949
F+ CL+ PE R TA LL+ PF+
Sbjct: 254 FTDFVKQCLVKSPEQRATATQLLQHPFV 281
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 201 bits (512), Expect = 4e-51
Identities = 112/283 (39%), Positives = 161/283 (56%), Gaps = 3/283 (1%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSK 751
DP +L+ L KIG+G+ G V+ + T VAIK ++LE+ + + E I EI V+
Sbjct: 31 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 90
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
+ + SYL LW++MEY+ GGS D++ L E QI + RE LKGL +LHS+
Sbjct: 91 SPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSE 150
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
IHRDIK+ N+LLS +G++KL DFG Q+ + +KR T VGTP+WMAPEV+ + Y
Sbjct: 151 KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDS 210
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K DIWSL PP+ P++ L+LI N P L+ GN S + F+ CL
Sbjct: 211 KADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE--GNYSKPLKEFVEACLN 268
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAES 974
+P R TA +LL+ FI A++ + L L+ + K +S
Sbjct: 269 KEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQS 311
>HsM5454174 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 199 bits (506), Expect = 2e-50
Identities = 112/272 (41%), Positives = 153/272 (56%), Gaps = 3/272 (1%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSK 751
DP +L+ L +IG+G+ G VY + T VAIK ++LE+ + + E I EI V+
Sbjct: 15 DPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 74
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
I + SYL LW++MEY+ GGS D++ L E I + RE LKGL +LHS+
Sbjct: 75 SPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSE 134
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
IHRDIK+ N+LLS GD+KL DFG Q+ + +KR T VGTP+WMAPEV+ + Y
Sbjct: 135 RKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF 194
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K DIWSL PP + P+R L+LI N P L+ G S F+ CL
Sbjct: 195 KADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE--GQHSKPFKEFVEACLN 252
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLV 963
DP R TA +LL+ FIT ++ + L L+
Sbjct: 253 KDPRFRPTAKELLKHKFITRYTKKTSFLTELI 284
>Hs21361358 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 199 bits (506), Expect = 2e-50
Identities = 112/272 (41%), Positives = 153/272 (56%), Gaps = 3/272 (1%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSK 751
DP +L+ L +IG+G+ G VY + T VAIK ++LE+ + + E I EI V+
Sbjct: 15 DPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 74
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
I + SYL LW++MEY+ GGS D++ L E I + RE LKGL +LHS+
Sbjct: 75 SPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSE 134
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
IHRDIK+ N+LLS GD+KL DFG Q+ + +KR T VGTP+WMAPEV+ + Y
Sbjct: 135 RKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF 194
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K DIWSL PP + P+R L+LI N P L+ G S F+ CL
Sbjct: 195 KADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE--GQHSKPFKEFVEACLN 252
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLV 963
DP R TA +LL+ FIT ++ + L L+
Sbjct: 253 KDPRFRPTAKELLKHKFITRYTKKTSFLTELI 284
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 197 bits (502), Expect = 5e-50
Identities = 110/288 (38%), Positives = 164/288 (56%), Gaps = 3/288 (1%)
Query: 683 SKLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNL-EKQPKKELIV 741
+ L + T DP+ Y+ L ++G+G+ G VY A +L T+ VA+K ++L E + E I
Sbjct: 234 TSLPDSITREDPTTKYEFLNELGKGSYGSVYKARDLKTSEIVAVKVISLTEGEEGYEEIR 293
Query: 742 NEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDV--VTHCILTEGQIGAVSR 799
EI +++ H N+V ++ SY LW+VMEY GGS+ D+ VT L E QI + R
Sbjct: 294 GEIEMLQQCNHPNVVRYLGSYQGEDYLWIVMEYCGGGSVADLMNVTEEALEEYQIAYICR 353
Query: 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWM 859
E LKGL +LHS +HRDIK NILL+ G++KL DFG AQ+ KR T +GTP+WM
Sbjct: 354 EALKGLAYLHSIYKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWM 413
Query: 860 APEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLS 919
APEV+ Y KVD+W+L PP + P+R L++I+ P L+D S
Sbjct: 414 APEVIQENRYDGKVDVWALGVSAIEMAEGLPPRSSVHPMRVLFMISIEPAPMLEDKEKWS 473
Query: 920 HKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
F+ CL +P R TAA++L+ F+ ++++P ++ +R
Sbjct: 474 LVFHDFVAKCLTKEPRLRPTAAEMLKHKFVERCKTGASAMSPKIEKSR 521
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 197 bits (501), Expect = 7e-50
Identities = 105/268 (39%), Positives = 152/268 (56%), Gaps = 4/268 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL+E T P +++ L K+G+G+ G V+ A + VAIKQ+ +E ++ I+ E
Sbjct: 13 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQE--IIKE 70
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ +V + SY DLW+VMEY GS++D++ + L E +I + + T
Sbjct: 71 ISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKST 130
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LKGL++LH IHRDIK+ NILL+ G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 131 LKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 190
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y DIWSL PPY + P+RA+++I TN P + P S
Sbjct: 191 EVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDD 250
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFI 949
F+ CL+ +PE R TA LL+ PFI
Sbjct: 251 FTDFVKKCLVKNPEQRATATQLLQHPFI 278
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 197 bits (501), Expect = 7e-50
Identities = 105/268 (39%), Positives = 152/268 (56%), Gaps = 4/268 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL+E T P +++ L K+G+G+ G V+ A + VAIKQ+ +E ++ I+ E
Sbjct: 13 KLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQE--IIKE 70
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ +V + SY DLW+VMEY GS++D++ + L E +I + + T
Sbjct: 71 ISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKST 130
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LKGL++LH IHRDIK+ NILL+ G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 131 LKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 190
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y DIWSL PPY + P+RA+++I TN P + P S
Sbjct: 191 EVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDD 250
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFI 949
F+ CL+ +PE R TA LL+ PFI
Sbjct: 251 FTDFVKKCLVKNPEQRATATQLLQHPFI 278
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 197 bits (500), Expect = 9e-50
Identities = 117/280 (41%), Positives = 160/280 (56%), Gaps = 8/280 (2%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
+P + ++ + +IG G G VY A + T AIK + LE ++ EI++MK KH
Sbjct: 11 NPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKH 70
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHS 810
NIV + SYL R LW+ ME+ GGSL D+ H L+E QI VSRETL+GL +LHS
Sbjct: 71 PNIVAYFGSYLRRDKLWICMEFCGGGSLQDIY-HVTGPLSELQIAYVSRETLQGLYYLHS 129
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV--VSRK- 867
KG +HRDIK NILL+ NG +KL DFG AQI KR + +GTPYWMAPEV V RK
Sbjct: 130 KGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKG 189
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNG--TPKLKDPGNLSHKMAMF 925
Y D+W++ PP + P+RAL+L+ + PKLKD S+ F
Sbjct: 190 GYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHF 249
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKL 965
+ L +P+ R TA LL+ PF+T+ + ++ L K+
Sbjct: 250 VKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKV 289
>Hs15011880 [T] KOG0201 Serine/threonine protein kinase
Length = 416
Score = 197 bits (500), Expect = 9e-50
Identities = 107/272 (39%), Positives = 156/272 (57%), Gaps = 3/272 (1%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSK 751
DP +L+ L +IG+G+ G V+ + T VAIK ++LE+ + + E I EI V+
Sbjct: 19 DPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 78
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
+ + + SYL LW++MEY+ GGS D++ E QI + +E LKGL +LHS+
Sbjct: 79 SSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSE 138
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
IHRDIK+ N+LLS GD+KL DFG Q+ + +KR T VGTP+WMAPEV+ + Y
Sbjct: 139 KKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDS 198
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K DIWSL PP + P+R L+LI N P L G+ + F++ CL
Sbjct: 199 KADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL--VGDFTKSFKEFIDACLN 256
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLV 963
DP R TA +LL+ FI + +++ + L L+
Sbjct: 257 KDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 194 bits (492), Expect = 7e-49
Identities = 110/279 (39%), Positives = 158/279 (56%), Gaps = 6/279 (2%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSK 751
DP ++ +IG+G+ G V+ + T VAIK ++LE+ + + + I EI+V+
Sbjct: 8 DPELIFTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCD 67
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
+ + S+L LW++MEY+ GGS D++ E IG + RE LKGL +LHS+
Sbjct: 68 SPYVTKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGIILREVLKGLDYLHSE 127
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
+HRDIK+ N+LLS GD+KL DFG Q+ KR T VGTP+WMAPEV+ + +Y
Sbjct: 128 RKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDA 187
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K DIWSL PP P+R L+LI N P+L G+ + F+ CL
Sbjct: 188 KADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPQL--TGSYTKSFKDFVEACLN 245
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKK 970
DPE+R TA +LL+ PFI + A++N L L+ R KK
Sbjct: 246 KDPENRPTAKELLKYPFIKK-AKKNAYLIDLID--RFKK 281
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 191 bits (486), Expect = 4e-48
Identities = 104/268 (38%), Positives = 152/268 (55%), Gaps = 4/268 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL P +++ + K+G+G+ G V+ A + +AIK++ ++ ++ I+ E
Sbjct: 49 KLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQE--IIKE 106
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ K +V + SY DLW+VMEY GS++D++ L+E +I AV R+T
Sbjct: 107 ISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDT 166
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LKGLQ+LH IHRDIK+ NILL+ +G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 167 LKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 226
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y K DIWSL PPY + P+RA+++I T P K P S +
Sbjct: 227 EVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSE 286
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFI 949
F+ CL+ PE+R TA L E FI
Sbjct: 287 FNDFIRSCLIKKPEERKTALRLCEHTFI 314
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 191 bits (486), Expect = 4e-48
Identities = 104/268 (38%), Positives = 152/268 (55%), Gaps = 4/268 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL P +++ + K+G+G+ G V+ A + +AIK++ ++ ++ I+ E
Sbjct: 21 KLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQE--IIKE 78
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ K +V + SY DLW+VMEY GS++D++ L+E +I AV R+T
Sbjct: 79 ISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDT 138
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LKGLQ+LH IHRDIK+ NILL+ +G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 139 LKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 198
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y K DIWSL PPY + P+RA+++I T P K P S +
Sbjct: 199 EVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSE 258
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFI 949
F+ CL+ PE+R TA L E FI
Sbjct: 259 FNDFIRSCLIKKPEERKTALRLCEHTFI 286
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 191 bits (486), Expect = 4e-48
Identities = 104/268 (38%), Positives = 152/268 (55%), Gaps = 4/268 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL P +++ + K+G+G+ G V+ A + +AIK++ ++ ++ I+ E
Sbjct: 21 KLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQE--IIKE 78
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ K +V + SY DLW+VMEY GS++D++ L+E +I AV R+T
Sbjct: 79 ISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDT 138
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LKGLQ+LH IHRDIK+ NILL+ +G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 139 LKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 198
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y K DIWSL PPY + P+RA+++I T P K P S +
Sbjct: 199 EVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSE 258
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFI 949
F+ CL+ PE+R TA L E FI
Sbjct: 259 FNDFIRSCLIKKPEERKTALRLCEHTFI 286
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 191 bits (486), Expect = 4e-48
Identities = 104/268 (38%), Positives = 152/268 (55%), Gaps = 4/268 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL P +++ + K+G+G+ G V+ A + +AIK++ ++ ++ I+ E
Sbjct: 49 KLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQE--IIKE 106
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ K +V + SY DLW+VMEY GS++D++ L+E +I AV R+T
Sbjct: 107 ISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDT 166
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
LKGLQ+LH IHRDIK+ NILL+ +G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 167 LKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 226
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y K DIWSL PPY + P+RA+++I T P K P S +
Sbjct: 227 EVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSE 286
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFI 949
F+ CL+ PE+R TA L E FI
Sbjct: 287 FNDFIRSCLIKKPEERKTALRLCEHTFI 314
>7302458 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 596
Score = 190 bits (482), Expect = 1e-47
Identities = 104/283 (36%), Positives = 160/283 (55%), Gaps = 5/283 (1%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNE 743
KL+E P K++ + K+G+G+ G VY A +++ VAIK + +E + I+ E
Sbjct: 28 KLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHE--IIKE 85
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRET 801
I +M+ +V + SY + DLW+ MEY GS++D++ LTE +I + +T
Sbjct: 86 ISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDT 145
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
L+GL +LH + IHRDIK+ NILL+ G KL DFG Q+ + KR T++GTP+WMAP
Sbjct: 146 LQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAP 205
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
EV+ Y DIWSL PPY P+RA+++I P ++P S +
Sbjct: 206 EVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTE 265
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
F++ CL+ +P+DR TA +LLE FI A+ + L P+++
Sbjct: 266 FIDFVSKCLVKEPDDRATATELLEHEFIRN-AKHRSILKPMLE 307
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 189 bits (481), Expect = 1e-47
Identities = 107/280 (38%), Positives = 158/280 (56%), Gaps = 3/280 (1%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSK 751
DP ++ +IG+G+ G VY + T VAIK ++LE+ + + E I EI V+
Sbjct: 27 DPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCD 86
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
+ + S+L LW++MEY+ GGS D+ L E I + RE LKGL++LHS+
Sbjct: 87 SQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSE 146
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
IHRDIK+ N+L+S +GD+K+ DFG Q+ E KR T VG+P+WMAPE++ + Y
Sbjct: 147 RKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSSYDY 206
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K DIWSL PP+ + P+R L+LI N P L+ S F+ CL
Sbjct: 207 KADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQG-SQWSKPFKEFVEMCLN 265
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKL 971
DPE+R +A+ LL+ FI A++N+ L L++ A +L
Sbjct: 266 KDPENRPSASTLLKHQFIKR-AKKNSILVDLIERAAEYRL 304
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 189 bits (481), Expect = 1e-47
Identities = 107/280 (38%), Positives = 158/280 (56%), Gaps = 3/280 (1%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSK 751
DP ++ +IG+G+ G VY + T VAIK ++LE+ + + E I EI V+
Sbjct: 29 DPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCD 88
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
+ + S+L LW++MEY+ GGS D+ L E I + RE LKGL++LHS+
Sbjct: 89 SQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSE 148
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
IHRDIK+ N+L+S +GD+K+ DFG Q+ E KR T VG+P+WMAPE++ + Y
Sbjct: 149 RKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSSYDY 208
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K DIWSL PP+ + P+R L+LI N P L+ S F+ CL
Sbjct: 209 KADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQG-SQWSKPFKEFVEMCLN 267
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKL 971
DPE+R +A+ LL+ FI A++N+ L L++ A +L
Sbjct: 268 KDPENRPSASTLLKHQFIKR-AKKNSILVDLIERAAEYRL 306
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 189 bits (481), Expect = 1e-47
Identities = 111/263 (42%), Positives = 149/263 (56%), Gaps = 6/263 (2%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
+P Y+ + KIG G G VY A + +N AIK + LE ++I EI++M+ +H
Sbjct: 21 NPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRH 80
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSK 811
NI+ + SYL R LW+ ME+ GGSL D+ LTE QI + RETLKGL++LHS
Sbjct: 81 PNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSM 140
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV--VSRK-E 868
G +HRDIK NILL+ GD+KL DFG AQI KR + +GTPYWMAPEV V RK
Sbjct: 141 GKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGG 200
Query: 869 YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNG--TPKLKDPGNLSHKMAMFL 926
Y DIW+ PP + P+RAL+L++ +G P L + S F+
Sbjct: 201 YNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFI 260
Query: 927 NWCLMVDPEDRGTAADLLEDPFI 949
L +P+ R TA LL+ PF+
Sbjct: 261 KTALTKNPKKRPTAERLLQHPFV 283
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 185 bits (469), Expect = 3e-46
Identities = 109/266 (40%), Positives = 150/266 (55%), Gaps = 8/266 (3%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
+P + Y+ + ++G G G VY A + T A+K + LE LI EI ++K KH
Sbjct: 15 NPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKH 74
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHS 810
NIV + SYL R LW+ MEY GGSL D+ H L+E QI V RETL+GL +LH+
Sbjct: 75 CNIVAYFGSYLSREKLWICMEYCGGGSLQDIY-HVTGPLSELQIAYVCRETLQGLAYLHT 133
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE-- 868
KG +HRDIK NILL+ +GD+KL DFG A+I KR + +GTPYWMAPEV + ++
Sbjct: 134 KGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNG 193
Query: 869 -YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNG--TPKLKDPGNLSHKMAMF 925
Y DIW++ PP + P+RAL+L++ + PKLKD S F
Sbjct: 194 GYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNF 253
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITE 951
+ L +P+ R TA LL F+ +
Sbjct: 254 VKIALTKNPKKRPTAERLLTHTFVAQ 279
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 184 bits (468), Expect = 5e-46
Identities = 108/270 (40%), Positives = 151/270 (55%), Gaps = 4/270 (1%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-ELIVNEILVMKGSK 751
D S L+K IG+G G VY Y + T AIK +NL+ + E + EI + K
Sbjct: 18 DVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLK 77
Query: 752 H-NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHS 810
+NI + SYL LW++ME+ GGSL ++ + E IG + RE L L+ +H
Sbjct: 78 QISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHK 137
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR-KEY 869
VIHRDIK+ N+L++ G++KL DFG AQ+N+ +L+R TM GTPYWMAPEV+ Y
Sbjct: 138 DNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYY 197
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWC 929
KVDIWSL PPY + LRA+ LI + P+L+D + S + F+ C
Sbjct: 198 DTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLED-RSYSTSLKEFIALC 256
Query: 930 LMVDPEDRGTAADLLEDPFITEIAEENTSL 959
L DP++R +A DLL+ FI TS+
Sbjct: 257 LDEDPKERLSADDLLKSKFIRAHKATPTSI 286
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 184 bits (467), Expect = 6e-46
Identities = 106/269 (39%), Positives = 155/269 (57%), Gaps = 7/269 (2%)
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVM---KGS 750
S Y L +G+G+ G VY T +VAIK +NL+ + + I E+ V+ K S
Sbjct: 7 SSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQS 66
Query: 751 KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHS 810
NI+ + SYL +LW++M+Y GGS+ ++ ++E I + RETL+ L+F+H
Sbjct: 67 DVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHH 126
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-SRKEY 869
G+IHRDIK+ NIL+SM+G++KL DFG A++N KR T +GTPYWMAPEV+ +EY
Sbjct: 127 AGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEY 186
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWC 929
DIWSL PP+ E P RA+YLIA P+L GN S + F+ C
Sbjct: 187 NVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLN--GNFSALLKEFIASC 244
Query: 930 LMVDPEDRGTAADLLEDPFITEIAEENTS 958
L P+ R +++LL+ FI + + + S
Sbjct: 245 LQDVPQRRLDSSELLKSKFIKQYSRMSIS 273
>CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 829
Score = 184 bits (467), Expect = 6e-46
Identities = 107/271 (39%), Positives = 152/271 (55%), Gaps = 9/271 (3%)
Query: 687 EICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILV 746
++ +P+ Y+ L ++G G G VY A ++ +++ A+K + LE +I EI+V
Sbjct: 4 DVIKRSNPADDYELLQRVGSGTYGEVYKARDIRSDSLAAVKVVKLEAGDNFAVIQQEIMV 63
Query: 747 MKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKG 804
++ H NI+ + SY+ R LW+VMEY GGSL D+ H L+E QI V RETL+G
Sbjct: 64 IRECSHPNIIAYFGSYIRRDRLWIVMEYCGGGSLQDIY-HLTGPLSELQIAFVCRETLRG 122
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV 864
L +LH+ G IHRDIK NILLS +GD+KL DFG AQI KR + +GTPYWMAPEV
Sbjct: 123 LNYLHNMGKIHRDIKGANILLSSSGDVKLADFGVAAQITATIGKRKSFIGTPYWMAPEVA 182
Query: 865 ---SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNG--TPKLKDPGNLS 919
R YG + D+W+ PP + P++ LYL+ +G P LKD +
Sbjct: 183 CVEKRGGYGMQCDVWATGITAIELGECQPPLFDLHPMQVLYLMTKSGYKPPHLKDKHRWT 242
Query: 920 HKMAMFLNWCLMVDPEDRGTAADLL-EDPFI 949
F+ CL +P+ R + LL PF+
Sbjct: 243 PLFHDFVRQCLTKNPKKRPSPEKLLTSHPFV 273
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 180 bits (456), Expect = 1e-44
Identities = 99/249 (39%), Positives = 149/249 (59%), Gaps = 5/249 (2%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-ELIVNEILVMKGSKHNNIVNFIDSY 762
IG+G+ G VY A++ N VAIK ++LE+ + E I EI V+ + I + SY
Sbjct: 21 IGRGSFGDVYKAFDKDLNKEVAIKVIDLEESEDEIEDIQKEISVLSQCRCPYITEYYGSY 80
Query: 763 LFRGDLWVVMEYMEGGSLTDVV-THCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSD 821
L + LW++MEYM GGS+ D++ ++ L E I ++R+ L +++LH++G IHRDIK+
Sbjct: 81 LHQTKLWIIMEYMAGGSVADLLQSNNPLDETSIACITRDLLHAVEYLHNEGKIHRDIKAA 140
Query: 822 NILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE-YGPKVDIWSLXX 880
NILLS NGD+K+ DFG AQ+ +R T VGTP+WMAPEV+ E Y K DIWSL
Sbjct: 141 NILLSENGDVKVADFGVSAQLTRTISRRKTFVGTPFWMAPEVIQNSEGYNEKADIWSLGI 200
Query: 881 XXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTA 940
PP + P+R L++I P+L + + S ++ F++ CL P +R +A
Sbjct: 201 TVIEMAKGEPPLADLHPMRVLFIIPRETPPQLDE--HFSRQVKEFVSLCLKKAPAERPSA 258
Query: 941 ADLLEDPFI 949
+L++ FI
Sbjct: 259 KELIKHRFI 267
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 179 bits (454), Expect = 2e-44
Identities = 100/249 (40%), Positives = 146/249 (58%), Gaps = 5/249 (2%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-ELIVNEILVMKGSKHNNIVNFIDSY 762
IG+G+ G VY A++ N VAIK ++LE+ + E I EI V+ + I + SY
Sbjct: 348 IGRGSFGDVYKAFDTELNKDVAIKVIDLEESEDEIEDIQKEISVLSQCRCPYITEYYGSY 407
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSD 821
L + LW++MEYM GGS+ D++ L E I ++R+ L +++LH++G IHRDIK+
Sbjct: 408 LHQTKLWIIMEYMAGGSVADLLQPGNPLDEISIACITRDLLHAVEYLHAEGKIHRDIKAA 467
Query: 822 NILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE-YGPKVDIWSLXX 880
NILLS NGD+K+ DFG AQ+ +R T VGTP+WMAPEV+ E Y K DIWSL
Sbjct: 468 NILLSENGDVKVADFGVSAQLTRTISRRKTFVGTPFWMAPEVIQNSEGYNEKADIWSLGI 527
Query: 881 XXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTA 940
PP + P+R L++I P+L + + S + F+++CL P +R A
Sbjct: 528 TMIEMAKGEPPLADLHPMRVLFIIPRESPPQLDE--HFSRPLKEFVSFCLKKAPAERPNA 585
Query: 941 ADLLEDPFI 949
+LL+ FI
Sbjct: 586 KELLKHRFI 594
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 179 bits (453), Expect = 2e-44
Identities = 106/288 (36%), Positives = 157/288 (53%), Gaps = 8/288 (2%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+++++ + ++G GA G VY A T A A K + + + + E + EI ++ H
Sbjct: 31 DPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDH 90
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHS 810
IV + +Y G LW+++E+ GG++ ++ LTE QI V R+ L+ L FLHS
Sbjct: 91 PYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHS 150
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-----S 865
K +IHRD+K+ N+L+++ GDI+L DFG A+ + KR + +GTPYWMAPEVV
Sbjct: 151 KRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMK 210
Query: 866 RKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMF 925
Y K DIWSL PP+ P+R L IA + P L P S + F
Sbjct: 211 DTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDF 270
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAE 973
L L +PE R +AA LLE PF++ I N +L LV A+ + + E
Sbjct: 271 LKIALDKNPETRPSAAQLLEHPFVSSIT-SNKALRELVAEAKAEVMEE 317
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 178 bits (451), Expect = 4e-44
Identities = 104/266 (39%), Positives = 146/266 (54%), Gaps = 8/266 (3%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP ++ L ++G G G VY A + T+ A+K + L+ + EI +++ +H
Sbjct: 11 DPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRH 70
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHS 810
N+V +I SYL LW+ ME+ GGSL ++ H L E QI V RE LKGL LHS
Sbjct: 71 PNVVAYIGSYLRNDRLWICMEFCGGGSLQEIY-HATGPLEERQIAYVCREALKGLHHLHS 129
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV--VSRK- 867
+G IHRDIK N+LL++ GD+KL DFG ++ KR + +GTPYWMAPEV V RK
Sbjct: 130 QGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKG 189
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNG--TPKLKDPGNLSHKMAMF 925
Y D+W+L PP + P+RAL L++ + PKL+D + F
Sbjct: 190 GYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHF 249
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITE 951
L L +P+ R TA LL+ PF T+
Sbjct: 250 LKLALTKNPKKRPTAEKLLQHPFTTQ 275
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 177 bits (450), Expect = 6e-44
Identities = 104/266 (39%), Positives = 146/266 (54%), Gaps = 8/266 (3%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP ++ L ++G G G VY A + T+ A+K + L+ + EI +++ +H
Sbjct: 10 DPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRH 69
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHS 810
N+V +I SYL LW+ ME+ GGSL ++ H L E QI V RE LKGL LHS
Sbjct: 70 PNVVAYIGSYLRNDRLWICMEFCGGGSLQEIY-HATGPLEERQIAYVCRERLKGLHHLHS 128
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV--VSRK- 867
+G IHRDIK N+LL++ GD+KL DFG ++ KR + +GTPYWMAPEV V RK
Sbjct: 129 QGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKG 188
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNG--TPKLKDPGNLSHKMAMF 925
Y D+W+L PP + P+RAL L++ + PKL+D + F
Sbjct: 189 GYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHF 248
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITE 951
L L +P+ R TA LL+ PF T+
Sbjct: 249 LKLALTKNPKKRPTAEKLLQHPFTTQ 274
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 173 bits (438), Expect = 1e-42
Identities = 97/288 (33%), Positives = 152/288 (52%), Gaps = 9/288 (3%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
+P ++ + ++G GA G VY A T+ A K ++ + + + E + EI ++ H
Sbjct: 29 NPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDH 88
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHS 810
NIV +D++ + +LW+++E+ GG++ V+ LTE QI V ++TL L +LH
Sbjct: 89 PNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHD 148
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-----S 865
+IHRD+K+ NIL +++GDIKL DFG A+ +R + +GTPYWMAPEVV
Sbjct: 149 NKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSK 208
Query: 866 RKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMF 925
+ Y K D+WSL PP+ P+R L IA + P L P S F
Sbjct: 209 DRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDF 268
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAE 973
L CL + + R T + LL+ PF+T + N + L+ A+ + E
Sbjct: 269 LKKCLEKNVDARWTTSQLLQHPFVT--VDSNKPIRELIAEAKAEVTEE 314
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 170 bits (431), Expect = 9e-42
Identities = 99/281 (35%), Positives = 146/281 (51%), Gaps = 16/281 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+ +++ + +G G G VY + T AIK MN+ + + E+ + ++ K S H
Sbjct: 16 DPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHH 75
Query: 753 NNIVNFIDSYLFR--------GDLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRET 801
N+ + +++ + LW+VME+ GS+TD+V + L E I + RE
Sbjct: 76 RNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREI 135
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
L+GL LH VIHRDIK N+LL+ + ++KL DFG AQ+++ +R T +GTPYWMAP
Sbjct: 136 LRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAP 195
Query: 862 EVVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPG 916
EV++ E Y + D+WSL PP + P+RAL+LI N PKLK
Sbjct: 196 EVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNK 255
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENT 957
+ K F+ L+ D R LL PFI E E T
Sbjct: 256 KWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQT 296
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 170 bits (431), Expect = 9e-42
Identities = 99/281 (35%), Positives = 146/281 (51%), Gaps = 16/281 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+ +++ + +G G G VY + T AIK MN+ + + E+ + ++ K S H
Sbjct: 16 DPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHH 75
Query: 753 NNIVNFIDSYLFR--------GDLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRET 801
N+ + +++ + LW+VME+ GS+TD+V + L E I + RE
Sbjct: 76 RNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREI 135
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
L+GL LH VIHRDIK N+LL+ + ++KL DFG AQ+++ +R T +GTPYWMAP
Sbjct: 136 LRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAP 195
Query: 862 EVVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPG 916
EV++ E Y + D+WSL PP + P+RAL+LI N PKLK
Sbjct: 196 EVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNK 255
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENT 957
+ K F+ L+ D R LL PFI E E T
Sbjct: 256 KWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQT 296
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 170 bits (431), Expect = 9e-42
Identities = 99/281 (35%), Positives = 146/281 (51%), Gaps = 16/281 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+ +++ + +G G G VY + T AIK MN+ + + E+ + ++ K S H
Sbjct: 16 DPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHH 75
Query: 753 NNIVNFIDSYLFR--------GDLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRET 801
N+ + +++ + LW+VME+ GS+TD+V + L E I + RE
Sbjct: 76 RNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREI 135
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
L+GL LH VIHRDIK N+LL+ + ++KL DFG AQ+++ +R T +GTPYWMAP
Sbjct: 136 LRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAP 195
Query: 862 EVVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPG 916
EV++ E Y + D+WSL PP + P+RAL+LI N PKLK
Sbjct: 196 EVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNK 255
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENT 957
+ K F+ L+ D R LL PFI E E T
Sbjct: 256 KWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQT 296
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 169 bits (427), Expect = 3e-41
Identities = 98/283 (34%), Positives = 151/283 (52%), Gaps = 15/283 (5%)
Query: 687 EICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILV 746
++ + DP+ +++ + +G G G VY + T AIK M++ + ++E+ + ++
Sbjct: 14 DLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML 73
Query: 747 MKGSKHNNIVNFIDSYLFRG------DLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAV 797
K S H NI + +++ + LW+VME+ GS+TD+V + L E I +
Sbjct: 74 KKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI 133
Query: 798 SRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPY 857
SRE L+GL LH VIHRDIK N+LL+ N ++KL DFG AQ++ +R T +GTPY
Sbjct: 134 SREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY 193
Query: 858 WMAPEVVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL 912
WMAPEV++ E Y + D+WS PP + P+RAL+LI N P+L
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRL 253
Query: 913 KDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEE 955
K S K F+ CL+ + R + LL+ PFI + E
Sbjct: 254 KSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNE 295
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 169 bits (427), Expect = 3e-41
Identities = 98/283 (34%), Positives = 151/283 (52%), Gaps = 15/283 (5%)
Query: 687 EICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILV 746
++ + DP+ +++ + +G G G VY + T AIK M++ + ++E+ + ++
Sbjct: 14 DLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML 73
Query: 747 MKGSKHNNIVNFIDSYLFRG------DLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAV 797
K S H NI + +++ + LW+VME+ GS+TD+V + L E I +
Sbjct: 74 KKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI 133
Query: 798 SRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPY 857
SRE L+GL LH VIHRDIK N+LL+ N ++KL DFG AQ++ +R T +GTPY
Sbjct: 134 SREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY 193
Query: 858 WMAPEVVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL 912
WMAPEV++ E Y + D+WS PP + P+RAL+LI N P+L
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRL 253
Query: 913 KDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEE 955
K S K F+ CL+ + R + LL+ PFI + E
Sbjct: 254 KSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNE 295
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 169 bits (427), Expect = 3e-41
Identities = 98/283 (34%), Positives = 151/283 (52%), Gaps = 15/283 (5%)
Query: 687 EICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILV 746
++ + DP+ +++ + +G G G VY + T AIK M++ + ++E+ + ++
Sbjct: 14 DLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML 73
Query: 747 MKGSKHNNIVNFIDSYLFRG------DLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAV 797
K S H NI + +++ + LW+VME+ GS+TD+V + L E I +
Sbjct: 74 KKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI 133
Query: 798 SRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPY 857
SRE L+GL LH VIHRDIK N+LL+ N ++KL DFG AQ++ +R T +GTPY
Sbjct: 134 SREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY 193
Query: 858 WMAPEVVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL 912
WMAPEV++ E Y + D+WS PP + P+RAL+LI N P+L
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRL 253
Query: 913 KDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEE 955
K S K F+ CL+ + R + LL+ PFI + E
Sbjct: 254 KSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNE 295
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 169 bits (427), Expect = 3e-41
Identities = 98/283 (34%), Positives = 151/283 (52%), Gaps = 15/283 (5%)
Query: 687 EICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILV 746
++ + DP+ +++ + +G G G VY + T AIK M++ + ++E+ + ++
Sbjct: 14 DLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML 73
Query: 747 MKGSKHNNIVNFIDSYLFRG------DLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAV 797
K S H NI + +++ + LW+VME+ GS+TD+V + L E I +
Sbjct: 74 KKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYI 133
Query: 798 SRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPY 857
SRE L+GL LH VIHRDIK N+LL+ N ++KL DFG AQ++ +R T +GTPY
Sbjct: 134 SREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY 193
Query: 858 WMAPEVVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL 912
WMAPEV++ E Y + D+WS PP + P+RAL+LI N P+L
Sbjct: 194 WMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRL 253
Query: 913 KDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEE 955
K S K F+ CL+ + R + LL+ PFI + E
Sbjct: 254 KSK-KWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNE 295
>Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 833
Score = 168 bits (426), Expect = 3e-41
Identities = 100/266 (37%), Positives = 144/266 (53%), Gaps = 8/266 (3%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP Y L ++G G G V+ A + + VA+K + +E + EIL++K +H
Sbjct: 12 DPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTLQKEILILKTCRH 71
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDV--VTHCILTEGQIGAVSRETLKGLQFLHS 810
NIV + SYL+ LW+ ME+ GSL D+ VT L+E QI V RE L+GL +LHS
Sbjct: 72 ANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGS-LSELQISYVCREVLQGLAYLHS 130
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVS---RK 867
+ IHRDIK NIL++ G+++L DFG AQI +R + +GTPYWMAPEV + +
Sbjct: 131 QKKIHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKG 190
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNG--TPKLKDPGNLSHKMAMF 925
Y DIWSL PP + PLR L+L+ +G P+LK+ G S F
Sbjct: 191 GYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNF 250
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITE 951
+ L P+ R +A +L +++
Sbjct: 251 IKVTLTKSPKKRPSATKMLSHQLVSQ 276
>SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase
Length = 471
Score = 167 bits (423), Expect = 7e-41
Identities = 95/254 (37%), Positives = 144/254 (56%), Gaps = 4/254 (1%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL-IVNEILVMKGSKHNNIV 756
Y L K+G G+ G V+ A E + +AIKQ++LE I E+ ++ +N++
Sbjct: 9 YTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVI 68
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHR 816
+ ++ LW++ME+M+GGS++ ++ L E I + RE L GL +LH + IHR
Sbjct: 69 QYYGCFVDGYTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNKIHR 128
Query: 817 DIKSDNILLSMN-GDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDI 875
DIK+ NILLS + G++KL DFG AQ++ +R T VGTP+WMAPEV+ + YG DI
Sbjct: 129 DIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSYGLAADI 188
Query: 876 WSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
WSL PP P+R ++ I + PKL D + S F++ CL ++P
Sbjct: 189 WSLGITAIEMANGIPPRATMHPMRVIFEIPQSEPPKLDD--HFSPTFRDFVSCCLDLNPN 246
Query: 936 DRGTAADLLEDPFI 949
R +A +LL+ PFI
Sbjct: 247 MRWSAKELLQHPFI 260
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 166 bits (421), Expect = 1e-40
Identities = 98/273 (35%), Positives = 146/273 (52%), Gaps = 15/273 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+ +++ + +G G G VY T AIK M++ + ++E+ + ++ K S H
Sbjct: 27 DPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNH 86
Query: 753 NNIVNFIDSYLFRG------DLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRETLK 803
NI + +++ + LW+VMEY GS+TD+V L E I + RE L+
Sbjct: 87 RNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILR 146
Query: 804 GLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV 863
GL +LHS VIHRDIK N+LL+ N ++KL DFG AQ++ +R T +GTPYWMAPEV
Sbjct: 147 GLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEV 206
Query: 864 VSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNL 918
++ E Y + D+WSL PP + P+RAL+LI N P+LK
Sbjct: 207 IACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSK-KW 265
Query: 919 SHKMAMFLNWCLMVDPEDRGTAADLLEDPFITE 951
S K F++ L+ D R +LL+ FI +
Sbjct: 266 SKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKD 298
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 166 bits (419), Expect = 2e-40
Identities = 100/273 (36%), Positives = 146/273 (52%), Gaps = 12/273 (4%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNL---EKQPKKELI 740
++ ++ DP +L+ L +IG G+ G VY A TN VAIK+M+ + K + I
Sbjct: 10 EIADLFYKDDPEELFIGLHEIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDI 69
Query: 741 VNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSR 799
+ E+ ++ KH N + + YL W+VMEY G + + H L E +I A++
Sbjct: 70 LKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITH 129
Query: 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWM 859
L GL +LHS +IHRDIK+ NILL+ G +KL DFG + + N + VGTPYWM
Sbjct: 130 GALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPAN----SFVGTPYWM 185
Query: 860 APEVV---SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPG 916
APEV+ +Y KVDIWSL PP N + ALY IA N +P L+
Sbjct: 186 APEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQS-N 244
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFI 949
+ F+++CL P++R T+A+LL F+
Sbjct: 245 EWTDSFRRFVDYCLQKIPQERPTSAELLRHDFV 277
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 165 bits (418), Expect = 3e-40
Identities = 98/273 (35%), Positives = 146/273 (52%), Gaps = 15/273 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+ +++ + +G G G VY + T AIK M++ + ++E+ ++ K S H
Sbjct: 20 DPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHH 79
Query: 753 NNIVNFIDSYLFRG------DLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRETLK 803
NI + +++ + LW+VME+ GS+TD+V + L E I + RE L+
Sbjct: 80 RNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILR 139
Query: 804 GLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV 863
GL LH+ VIHRDIK N+LL+ N ++KL DFG AQ++ +R T +GTPYWMAPEV
Sbjct: 140 GLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEV 199
Query: 864 VSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNL 918
++ E Y + DIWSL PP + P+RAL+LI N P+LK
Sbjct: 200 IACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSK-KW 258
Query: 919 SHKMAMFLNWCLMVDPEDRGTAADLLEDPFITE 951
S K F++ CL+ R LL+ PFI +
Sbjct: 259 SKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRD 291
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 165 bits (417), Expect = 4e-40
Identities = 114/297 (38%), Positives = 151/297 (50%), Gaps = 11/297 (3%)
Query: 683 SKLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-ELIV 741
SK I + PSKLY IG+G G VY A + T VAIK +NLE + EL+
Sbjct: 3 SKEISIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLA 62
Query: 742 NEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI---LTEGQIGAVS 798
EI + K I N+I + L +W+VMEY GGS +D++ L E ++ +
Sbjct: 63 QEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFII 122
Query: 799 RETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYW 858
E GL++LH + IHRDIK+ NILL+ G +KL DFG I LKR T VGTPYW
Sbjct: 123 HEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRS-TLKRDTFVGTPYW 181
Query: 859 MAPEVVSRK--EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPG 916
MAPEVV + Y K DIWSL PP P++ + + PKL+ P
Sbjct: 182 MAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP- 240
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAE 973
S F+ CL+ P DR +A +LL F+ I T+L V L + KK+ E
Sbjct: 241 -FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNIT--ITNLKSDVDLIKQKKVQE 294
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 164 bits (416), Expect = 5e-40
Identities = 108/300 (36%), Positives = 152/300 (50%), Gaps = 36/300 (12%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNNIVNFIDSY 762
IG GA+ V AY VAIK++NLEK Q + ++ EI M H NIV++ S+
Sbjct: 23 IGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSF 82
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCI---------LTEGQIGAVSRETLKGLQFLHSKGV 813
+ + +LW+VM+ + GGS+ D++ H + L E I + RE L+GL++LH G
Sbjct: 83 VVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQ 142
Query: 814 IHRDIKSDNILLSMNGDIKLTDFG---FCAQINEV--NLKRTTMVGTPYWMAPEVVSR-K 867
IHRD+K+ NILL +G +++ DFG F A ++ N R T VGTP WMAPEV+ + +
Sbjct: 143 IHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVR 202
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPK----------LKDPGN 917
Y K DIWS PY P++ L L N P LK G
Sbjct: 203 GYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGK 262
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITE------IAEENTSLAPLVKLARMKKL 971
KM ++ CL DPE R TAA+LL F + + E+ AP + R KK+
Sbjct: 263 SFRKM---ISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTIS-ERAKKV 318
>7293601 [T] KOG0577 Serine/threonine protein kinase
Length = 1039
Score = 164 bits (416), Expect = 5e-40
Identities = 108/299 (36%), Positives = 153/299 (51%), Gaps = 15/299 (5%)
Query: 684 KLTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNL---EKQPKKELI 740
++ ++ DP K++++L +IG G+ G VY A T VAIK+M+ + Q K + I
Sbjct: 13 EIADLFNKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDI 72
Query: 741 VNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSR 799
+ EI ++ H N + + YL W+VMEY G + + H L E +I A+
Sbjct: 73 LKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICL 132
Query: 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWM 859
L GL +LHS G IHRDIK+ NILL+ NG +KL DFG A + + VGTPYWM
Sbjct: 133 GVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAA----IKCPANSFVGTPYWM 188
Query: 860 APEVV---SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPG 916
APEV+ +Y KVD+WSL PPY N + ALY IA N +P L
Sbjct: 189 APEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPTL-PKN 247
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAESM 975
+ S F+ CL P +R ++A LL ++T +T L L+ AR K +
Sbjct: 248 DWSDAFCSFVELCLKKMPAERPSSAKLLTHAYVTR-PRSDTVLLELI--ARTKSAVREL 303
>7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1726
Score = 164 bits (415), Expect = 6e-40
Identities = 96/264 (36%), Positives = 136/264 (51%), Gaps = 7/264 (2%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP++ ++ + ++G GA G VY A A K LE + + EI ++ KH
Sbjct: 32 DPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKH 91
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHS 810
NIV +++ LW+++EY +GG+L ++ LTE QI V + +GL FLH
Sbjct: 92 PNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHR 151
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-----S 865
VIHRD+K+ N+LL+M G +KL DFG A+ K T +GTPYWMAPE+V
Sbjct: 152 NKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFR 211
Query: 866 RKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMF 925
Y KVDIWSL PP +P+R L I + PKL+ P S + F
Sbjct: 212 DNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDF 271
Query: 926 LNWCLMVDPEDRGTAADLLEDPFI 949
L L+ DP+ R T L++ FI
Sbjct: 272 LKKSLVKDPQVRPTTDVLMQHAFI 295
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 164 bits (414), Expect = 8e-40
Identities = 95/252 (37%), Positives = 137/252 (53%), Gaps = 7/252 (2%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFID 760
+IG+GA G VY +L VAIKQ++LE +++L I+ EI ++K H NIV ++
Sbjct: 25 EIGKGAYGRVYIGLDLENGDFVAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIVKYLG 84
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVT---HCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
S + L +++EY+E GSL +++ E + + L+GL +LH +GVIHRD
Sbjct: 85 SLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRD 144
Query: 818 IKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWS 877
IK NIL + G +KL DFG ++NE + ++VGTPYWMAPEV+ DIWS
Sbjct: 145 IKGANILTTKEGLVKLADFGVATKLNEADFNTHSVVGTPYWMAPEVIELSGVCAASDIWS 204
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
+ PPY + P+ ALY I + TP + P +LS + FL C D R
Sbjct: 205 VGCTIIELLTCVPPYYDLQPMPALYRIVQDDTPPI--PDSLSPDITDFLRLCFKKDSRQR 262
Query: 938 GTAADLLEDPFI 949
A LL P+I
Sbjct: 263 PDAKTLLSHPWI 274
>7293247 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 575
Score = 163 bits (413), Expect = 1e-39
Identities = 78/156 (50%), Positives = 111/156 (71%)
Query: 685 LTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEI 744
L + + GDP + + KIG+G++G V A + T VA+K+M+L KQ ++EL+ NE+
Sbjct: 355 LQMVVSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEV 414
Query: 745 LVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKG 804
++M+ H NIV S+L +LWVVMEY+EGG+LTD+VTH + E QI V ++ LK
Sbjct: 415 VIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHSRMDEEQIATVCKQCLKA 474
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCA 840
L +LHS+GVIHRDIKSD+ILL+ +G +KL+DFGFCA
Sbjct: 475 LAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCA 510
>Hs7706401 [T] KOG0577 Serine/threonine protein kinase
Length = 1235
Score = 162 bits (410), Expect = 2e-39
Identities = 101/272 (37%), Positives = 147/272 (53%), Gaps = 12/272 (4%)
Query: 685 LTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IV 741
+ E+ DP KL+ +L +IG G+ G VY A ++ + VAIK+M+ + E I+
Sbjct: 15 VAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDII 74
Query: 742 NEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRE 800
E+ ++ +H N + + YL W+VMEY G + + H L E +I AV+
Sbjct: 75 KEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHG 134
Query: 801 TLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMA 860
L+GL +LHS +IHRD+K+ NILLS G +KL DFG + + N + VGTPYWMA
Sbjct: 135 ALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN----SFVGTPYWMA 190
Query: 861 PEVV---SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN 917
PEV+ +Y KVD+WSL PP N + ALY IA N +P L+ G+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQS-GH 249
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFI 949
S F++ CL P+DR T+ LL+ F+
Sbjct: 250 WSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFV 281
>Hs4759208 [T] KOG0577 Serine/threonine protein kinase
Length = 1049
Score = 162 bits (410), Expect = 2e-39
Identities = 101/272 (37%), Positives = 147/272 (53%), Gaps = 12/272 (4%)
Query: 685 LTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IV 741
+ E+ DP KL+ +L +IG G+ G VY A ++ + VAIK+M+ + E I+
Sbjct: 15 VAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDII 74
Query: 742 NEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRE 800
E+ ++ +H N + + YL W+VMEY G + + H L E +I AV+
Sbjct: 75 KEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHG 134
Query: 801 TLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMA 860
L+GL +LHS +IHRD+K+ NILLS G +KL DFG + + N + VGTPYWMA
Sbjct: 135 ALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN----SFVGTPYWMA 190
Query: 861 PEVV---SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN 917
PEV+ +Y KVD+WSL PP N + ALY IA N +P L+ G+
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQS-GH 249
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFI 949
S F++ CL P+DR T+ LL+ F+
Sbjct: 250 WSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFV 281
>Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 162 bits (410), Expect = 2e-39
Identities = 99/282 (35%), Positives = 146/282 (51%), Gaps = 15/282 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DPS ++ IG+G G V+ A+K ++ +E+ ++ S H
Sbjct: 16 DPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDH 75
Query: 753 NNIVNFIDSYLFR----GD-LWVVMEYMEGGSLTDVVTHCI-----LTEGQIGAVSRETL 802
N+V F Y + GD LW+V+E GGS+TD+V + ++E I + E L
Sbjct: 76 PNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEAL 135
Query: 803 KGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPE 862
GLQ LH+ IHRD+K +NILL+ G +KL DFG AQ+ +R T VGTP+WMAPE
Sbjct: 136 MGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPE 195
Query: 863 VVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN 917
V++ ++ Y + D WSL PP + P+RAL+ I N PKL+ P
Sbjct: 196 VIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPEL 255
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSL 959
S + F++ CL D E R T ++LL+ FIT+I ++ L
Sbjct: 256 WSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVML 297
>Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 162 bits (410), Expect = 2e-39
Identities = 99/282 (35%), Positives = 146/282 (51%), Gaps = 15/282 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DPS ++ IG+G G V+ A+K ++ +E+ ++ S H
Sbjct: 16 DPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDH 75
Query: 753 NNIVNFIDSYLFR----GD-LWVVMEYMEGGSLTDVVTHCI-----LTEGQIGAVSRETL 802
N+V F Y + GD LW+V+E GGS+TD+V + ++E I + E L
Sbjct: 76 PNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEAL 135
Query: 803 KGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPE 862
GLQ LH+ IHRD+K +NILL+ G +KL DFG AQ+ +R T VGTP+WMAPE
Sbjct: 136 MGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPE 195
Query: 863 VVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN 917
V++ ++ Y + D WSL PP + P+RAL+ I N PKL+ P
Sbjct: 196 VIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPEL 255
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSL 959
S + F++ CL D E R T ++LL+ FIT+I ++ L
Sbjct: 256 WSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVML 297
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 161 bits (408), Expect = 4e-39
Identities = 93/252 (36%), Positives = 137/252 (53%), Gaps = 7/252 (2%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFID 760
+IG+GA G VY +L VAIKQ++LE +++L I+ EI ++K H NIV ++
Sbjct: 25 EIGKGAYGRVYKGLDLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLG 84
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVT---HCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
S + L +++EY+E GSL +++ E + + L+GL +LH +GVIHRD
Sbjct: 85 SSKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHRD 144
Query: 818 IKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWS 877
IK NIL + G +KL DFG ++NE ++ ++VGTPYWMAPEV+ DIWS
Sbjct: 145 IKGANILTTKEGLVKLADFGVATKLNEADVNTHSVVGTPYWMAPEVIEMSGVCAASDIWS 204
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
+ PPY + P+ AL+ I + P + P +LS + FL C D R
Sbjct: 205 VGCTVIELLTCVPPYYDLQPMPALFRIVQDDNPPI--PDSLSPDITDFLRQCFKKDSRQR 262
Query: 938 GTAADLLEDPFI 949
A LL P+I
Sbjct: 263 PDAKTLLSHPWI 274
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 157 bits (397), Expect = 8e-38
Identities = 95/268 (35%), Positives = 143/268 (52%), Gaps = 4/268 (1%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-ELIVNEILVMKGSKHNNIV 756
Y++L IGQG+ G V+ A ++ ++ VA+K ++L+ + E + EI + +I
Sbjct: 6 YRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHIT 65
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIH 815
+ S++ LW+ MEY +GGS D++ +E I V R+ L+ L +LH +G +H
Sbjct: 66 KYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMH 125
Query: 816 RDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDI 875
RDIK+ NIL +G +KL DFG Q+ + K VGTP+WMAPEVV + Y K DI
Sbjct: 126 RDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNYKADI 185
Query: 876 WSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
WSL PPY P++ L LI + P L + S F++ CL +P+
Sbjct: 186 WSLGITAYELATGEPPYSGIHPMKVLLLIPKHSPPSL-ERSKFSRAFCDFVSNCLKKNPK 244
Query: 936 DRGTAADLLEDPFITEIAEENTSLAPLV 963
DR TA L + FI + NTS+ +V
Sbjct: 245 DRATAEYLSKHKFIKKYC-PNTSVKEVV 271
>Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 357
Score = 153 bits (386), Expect = 1e-36
Identities = 89/272 (32%), Positives = 136/272 (49%), Gaps = 15/272 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+ ++ + IG+G G VY + A+K ++ +E+ ++ H
Sbjct: 22 DPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFLPNH 81
Query: 753 NNIVNFIDSYL-----FRGDLWVVMEYMEGGSLTDVVTHCI-----LTEGQIGAVSRETL 802
N+V F + G LW+V+E GGS+T++V + L E I + L
Sbjct: 82 PNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGAL 141
Query: 803 KGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPE 862
GLQ LH+ +IHRD+K +NILL+ G +KL DFG AQ+ L+R T VGTP+WMAPE
Sbjct: 142 LGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPE 201
Query: 863 VVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN 917
V++ ++ Y + D+WSL PP + P++ L+ I N P L P
Sbjct: 202 VIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEK 261
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFI 949
+ F++ CL+ D E R + LL+ PFI
Sbjct: 262 WCEEFNHFISQCLIKDFERRPSVTHLLDHPFI 293
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 152 bits (385), Expect = 2e-36
Identities = 106/311 (34%), Positives = 149/311 (47%), Gaps = 36/311 (11%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNNIV 756
YK IG GA+ V+TAY L N VAIK +NLEK Q + + +EI M H N+V
Sbjct: 57 YKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCQTSVDELSHEIQAMSQCNHPNVV 116
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI------------LTEGQIGAVSRETLKG 804
++ S++ + +LWVVM + GS+ D++ + L E I V RE LKG
Sbjct: 117 SYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKG 176
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEV------NLKRTTMVGTPYW 858
L++ H G IHRDIK+ NILL+ +G I++ DFG + R T VGTP W
Sbjct: 177 LEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGTPCW 236
Query: 859 MAPEVVSRKE-YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN 917
MAPEV+ + + Y K DIWSL PY P++ L L N P L+
Sbjct: 237 MAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAE 296
Query: 918 LSHKMAMF-------LNWCLMVDPEDRGTAADLL---------EDPFITEIAEENTSLAP 961
+ + + CL DP R TA++LL + ++ EN + P
Sbjct: 297 RKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFKKGKDKKYLVHTLIENLASVP 356
Query: 962 LVKLARMKKLA 972
+V KK+A
Sbjct: 357 VVAHHSSKKVA 367
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 151 bits (382), Expect = 4e-36
Identities = 95/268 (35%), Positives = 137/268 (50%), Gaps = 23/268 (8%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNNIVNFIDSY 762
IG GA+ V A VAIK++NLEK Q + ++ EI M H N+V + S+
Sbjct: 71 IGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSF 130
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCI---------LTEGQIGAVSRETLKGLQFLHSKGV 813
+ + +LW+VM+ + GGS+ D++ + + L E I + +E L+GL +LH G
Sbjct: 131 VVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQ 190
Query: 814 IHRDIKSDNILLSMNGDIKLTDFG---FCAQINEV--NLKRTTMVGTPYWMAPEVVSR-K 867
IHRD+K+ NILL +G +++ DFG F A +V N R T VGTP WMAPEV+ + +
Sbjct: 191 IHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVR 250
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMF-- 925
Y K D+WS PY P++ L L N P L+ M +
Sbjct: 251 GYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGK 310
Query: 926 -----LNWCLMVDPEDRGTAADLLEDPF 948
L+ CL DP R TAA+LL+ F
Sbjct: 311 SFRKLLSLCLQKDPSKRPTAAELLKCKF 338
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 150 bits (380), Expect = 7e-36
Identities = 91/249 (36%), Positives = 132/249 (52%), Gaps = 7/249 (2%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIV--NEILVMKGSKHNNIVNFIDS 761
+G+GA G VY + +VA+K++ L K K +L V EI ++K H NIV + S
Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGS 74
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
Y L +++EY E GSL + + + E + + + L+GL +LH++GVIHRDIK
Sbjct: 75 YQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKG 134
Query: 821 DNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXX 880
NIL + +G IKL DFG +IN L+ ++VG+PYWMAPEV+ DIWS+
Sbjct: 135 ANILTTKDGTIKLADFGVATKINA--LEDHSVVGSPYWMAPEVIELVGATTASDIWSVGC 192
Query: 881 XXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTA 940
PPY + P AL+ + + P L P N+S FL C DP R
Sbjct: 193 TVIELLDGNPPYYDLDPTSALFRMVKDEHPPL--PSNISSAAKSFLMQCFQKDPNLRIKT 250
Query: 941 ADLLEDPFI 949
LL+ P++
Sbjct: 251 RKLLKHPWV 259
>7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 326
Score = 147 bits (371), Expect = 8e-35
Identities = 91/294 (30%), Positives = 148/294 (49%), Gaps = 19/294 (6%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKH 752
DP+ ++ +I QG + V+ A EL + VA+K + +++ + + + H
Sbjct: 11 DPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKIQHYDEEHQVSIEEEYRTLRDYCDH 70
Query: 753 NNIVNFIDSYLFR-----GDLWVVMEYMEGGSLTDVVTHCI-----LTEGQIGAVSRETL 802
N+ F Y ++W VMEY GG+ D+V + + E I + RET
Sbjct: 71 PNLPEFYGVYKLSKPNGPDEIWFVMEYCAGGTAVDMVNKLLKLDRRMREEHIAYIIRETC 130
Query: 803 KGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPE 862
+ L+ V+HRDI+ DNILL+ NG +KL DFG Q++ KR T +G+P WMAPE
Sbjct: 131 RAAIELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDSTLGKRGTCIGSPCWMAPE 190
Query: 863 VVSRKE-----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN 917
VVS E + D+W+L PP+ + P RA++ I N P L P N
Sbjct: 191 VVSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTN 250
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEE----NTSLAPLVKLAR 967
S ++ F++ L + E+R +++E PF+TE+ E + +A +++L+R
Sbjct: 251 WSQQINDFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSR 304
>At4g08500 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 147 bits (370), Expect = 1e-34
Identities = 90/254 (35%), Positives = 141/254 (55%), Gaps = 13/254 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-----ELIVNEILVMKGSKHNNIVNF 758
+G+G+ G VY G A+K+++L Q + + + EI ++ +H NIV +
Sbjct: 339 LGRGSFGSVYEGIS-GDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQHQNIVRY 397
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ +L++ +E + GSL + L + + +R+ L GL++LH KG IHRDI
Sbjct: 398 RGTAKDGSNLYIFLELVTQGSLLKLYQRYQLRDSVVSLYTRQILDGLKYLHDKGFIHRDI 457
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE---YGPKVDI 875
K NIL+ NG +KL DFG A++++ N ++ GTP+WMAPEV++RK+ YG DI
Sbjct: 458 KCANILVDANGAVKLADFGL-AKVSKFNDIKSCK-GTPFWMAPEVINRKDSDGYGSPADI 515
Query: 876 WSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
WSL PY + P++AL+ I P++ P LS +F+ CL V+PE
Sbjct: 516 WSLGCTVLEMCTGQIPYSDLEPVQALFRIGRGTLPEV--PDTLSLDARLFILKCLKVNPE 573
Query: 936 DRGTAADLLEDPFI 949
+R TAA+LL PF+
Sbjct: 574 ERPTAAELLNHPFV 587
>At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 561
Score = 143 bits (360), Expect = 2e-33
Identities = 95/264 (35%), Positives = 128/264 (47%), Gaps = 10/264 (3%)
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHN 753
+K YK +IG G S V+ A + N VAIK ++LEK + I E+ M H
Sbjct: 13 AKDYKLYEEIGDGVSATVHRALCIPLNVVVAIKVLDLEKCNNDLDGIRREVQTMSLINHP 72
Query: 754 NIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI---LTEGQIGAVSRETLKGLQFLHS 810
N++ S+ LWVVM YM GGS ++ E I + RETLK L +LH+
Sbjct: 73 NVLQAHCSFTTGHQLWVVMPYMAGGSCLHIIKSSYPDGFEEPVIATLLRETLKALVYLHA 132
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRK 867
G IHRD+K+ NILL NG +KL DFG A + R T VGTP WMAPEV+ +
Sbjct: 133 HGHIHRDVKAGNILLDSNGAVKLADFGVSACMFDTGDRQRSRNTFVGTPCWMAPEVMQQL 192
Query: 868 E-YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL--KDPGNLSHKMAM 924
Y K D+WS P+ P++ L + N P L + S
Sbjct: 193 HGYDFKADVWSFGITALELAHGHAPFSKYPPMKVLLMTLQNAPPGLDYERDKRFSKAFKE 252
Query: 925 FLNWCLMVDPEDRGTAADLLEDPF 948
+ CL+ DP+ R T+ LL+ PF
Sbjct: 253 MVGTCLVKDPKKRPTSEKLLKHPF 276
>CE01405 [T] KOG0577 Serine/threonine protein kinase
Length = 982
Score = 142 bits (357), Expect = 3e-33
Identities = 96/280 (34%), Positives = 142/280 (50%), Gaps = 22/280 (7%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IVNEILVMKG 749
DP + Y++L +IG G+ G VY AY+ +VAIK+MN + E I+ E+ +
Sbjct: 25 DPEQRYQDLREIGHGSFGAVYFAYDKKNEQTVAIKKMNFSGKQAVEKWNDILKEVSFLNT 84
Query: 750 SKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEG----QIGAVSRETLKGL 805
H +IV++ +L W+VMEY G S D+V +L +G +I A+ +TL L
Sbjct: 85 VVHPHIVDYKACFLKDTTCWLVMEYCIG-SAADIVD--VLRKGMREVEIAAICSQTLDAL 141
Query: 806 QFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV- 864
++LHS IHRDIK+ NILLS + +KL DFG + ++ T +GTP++MAPEV+
Sbjct: 142 RYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVDPAQ----TFIGTPFFMAPEVIL 197
Query: 865 --SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL-----KDPGN 917
Y + DIWSL PP + + ALY IA N P L +
Sbjct: 198 AMDEGHYTDRADIWSLGITCIELAERRPPLFSMNAMSALYHIAQNDPPTLSPIDTSEQPE 257
Query: 918 LSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENT 957
S + F++ CL E+R +A + PFI +T
Sbjct: 258 WSLEFVQFIDKCLRKPAEERMSAEECFRHPFIQRSRPSDT 297
>At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 487
Score = 141 bits (356), Expect = 4e-33
Identities = 101/282 (35%), Positives = 138/282 (48%), Gaps = 29/282 (10%)
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASV-AIKQMNLEKQPKK-ELIVNEILVMKGSKH 752
++ Y+ + KIG G S VY A + N+ V AIK ++L++ + + E M H
Sbjct: 12 AEAYEIICKIGVGVSASVYKAICIPMNSMVVAIKAIDLDQSRADFDSLRRETKTMSLLSH 71
Query: 753 NNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI---LTEGQIGAVSRETLKGLQFLH 809
NI+N S+ LWVVM +M GSL +V+ L E I +ETL + +LH
Sbjct: 72 PNILNAYCSFTVDRCLWVVMPFMSCGSLHSIVSSSFPSGLPENCISVFLKETLNAISYLH 131
Query: 810 SKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINE----------VNLKRTTMVGTPYWM 859
+G +HRDIK+ NIL+ +G +KL DFG A I E +L+ T + GTPYWM
Sbjct: 132 DQGHLHRDIKAGNILVDSDGSVKLADFGVSASIYEPVTSSSGTTSSSLRLTDIAGTPYWM 191
Query: 860 APEVV-SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRAL------------YLIAT 906
APEVV S YG K DIWS PP + PL++L Y I T
Sbjct: 192 APEVVHSHTGYGFKADIWSFGITALELAHGRPPLSHLPPLKSLLMKITKRFHFSDYEINT 251
Query: 907 NGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPF 948
+G+ K K S + CL DP R +A LL+ PF
Sbjct: 252 SGSSK-KGNKKFSKAFREMVGLCLEQDPTKRPSAEKLLKHPF 292
>Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 626
Score = 139 bits (351), Expect = 2e-32
Identities = 91/257 (35%), Positives = 137/257 (52%), Gaps = 15/257 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK---QPKKEL--IVNEILVMKGSKHNNIVNF 758
+GQGA G VY Y++ T +A KQ+ + + KE+ + EI ++K +H IV +
Sbjct: 368 LGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQY 427
Query: 759 IDSYLFRGD--LWVVMEYMEGGSLTDVV-THCILTEGQIGAVSRETLKGLQFLHSKGVIH 815
R + L + MEYM GGS+ D + + LTE +R+ L+G+ +LHS ++H
Sbjct: 428 YGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVH 487
Query: 816 RDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTM---VGTPYWMAPEVVSRKEYGPK 872
RDIK NIL G++KL DFG ++ + + T M GTPYWM+PEV+S + YG K
Sbjct: 488 RDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRK 547
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGT-PKLKDPGNLSHKMAMFLNWCLM 931
D+WSL PP+ + A++ IAT T P+L P ++S FL +
Sbjct: 548 ADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQL--PSHISEHGRDFLR-RIF 604
Query: 932 VDPEDRGTAADLLEDPF 948
V+ R +A +LL F
Sbjct: 605 VEARQRPSAEELLTHHF 621
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 139 bits (350), Expect = 2e-32
Identities = 85/262 (32%), Positives = 137/262 (51%), Gaps = 17/262 (6%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK--------ELIVNEILVMKGSKHNNI 755
IG G+ G VY + +A+KQ+ L+ + + + EI +++ H +I
Sbjct: 103 IGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEHI 162
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V ++ S L L + +EY+ GGS+ ++T + E + ++TLKGL++LHS+G++
Sbjct: 163 VQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRGIV 222
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFC--AQINEVNLK----RTTMVGTPYWMAPEVVSRKE 868
HRDIK NIL+ G IK++DFG ++N + K R + G+ +WMAPEVV +
Sbjct: 223 HRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTM 282
Query: 869 YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNW 928
+ K DIWSL PY N ++A++ I N P+ P N+S FL
Sbjct: 283 HTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGENILPEF--PSNISSSAIDFLEK 340
Query: 929 CLMVDPEDRGTAADLLEDPFIT 950
+D R TA++LL PF++
Sbjct: 341 TFAIDCNLRPTASELLSHPFVS 362
>HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 618
Score = 138 bits (348), Expect = 4e-32
Identities = 93/258 (36%), Positives = 137/258 (53%), Gaps = 15/258 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQ-PKKELIVN----EILVMKGSKHNNIVNF 758
+GQGA G VY Y++ T +A+KQ+ + P+ VN EI ++K H IV +
Sbjct: 361 LGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNFLHERIVQY 420
Query: 759 IDSYLFRGD--LWVVMEYMEGGSLTDVV-THCILTEGQIGAVSRETLKGLQFLHSKGVIH 815
+ L + MEYM GGS+ D + + LTE +R+ L+G+ +LHS ++H
Sbjct: 421 YGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENGTRKYTRQILEGVHYLHSNMILH 480
Query: 816 RDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTM---VGTPYWMAPEVVSRKEYGPK 872
RDIK NIL G++KL DFG ++ + L T M GTPYWM+PEV+S + YG K
Sbjct: 481 RDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGQGYGRK 540
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGT-PKLKDPGNLSHKMAMFLNWCLM 931
DIWS+ PP+ + A++ IAT T PKL P ++S FL +
Sbjct: 541 ADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKL--PPHVSDYTRDFLK-RIF 597
Query: 932 VDPEDRGTAADLLEDPFI 949
V+ + R +A +LL F+
Sbjct: 598 VEAKLRPSADELLRHMFV 615
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 138 bits (347), Expect = 5e-32
Identities = 95/282 (33%), Positives = 139/282 (48%), Gaps = 10/282 (3%)
Query: 685 LTEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEI 744
LT I + S Y IG+G+ G VY A T+ VAIK++ E + I+ EI
Sbjct: 12 LTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEI 71
Query: 745 LVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETL 802
++K HNNIV + +L++++EY GSL +++ L+E + +TL
Sbjct: 72 SLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTL 131
Query: 803 KGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPE 862
GL++LH +GVIHRDIK+ NILLS + +KL DFG +N L T+ GT WMAPE
Sbjct: 132 LGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL---TLAGTLNWMAPE 188
Query: 863 VVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKM 922
++ + DIWSL PPY N T Y + + P + S +
Sbjct: 189 ILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVEND---TYYPPSSFSEPL 245
Query: 923 AMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
FL+ C + + R TA LL+ +I + EN + L K
Sbjct: 246 KDFLSKCFVKNMYKRPTADQLLKHVWIN--STENVKVDKLNK 285
>Hs22045241 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 122
Score = 137 bits (344), Expect = 1e-31
Identities = 69/116 (59%), Positives = 84/116 (71%), Gaps = 1/116 (0%)
Query: 852 MVGTPYWMAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPK 911
MVGTPYWMAPEVV+RK YGPKVDIWSL PPYLNE PLRALYLIATNGTP+
Sbjct: 1 MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPE 60
Query: 912 LKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLAR 967
L++P LS FLN CL +D E RG+A +LL+ PF+ ++A+ +SL PL+ A+
Sbjct: 61 LQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL-KLAKPLSSLTPLIMAAK 115
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 135 bits (341), Expect = 2e-31
Identities = 90/254 (35%), Positives = 131/254 (51%), Gaps = 11/254 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNL--EKQPKKELIVN---EILVMKGSKHNNIVNF 758
+G G G VY + AIK++ + + Q KE + EI ++ H NIV +
Sbjct: 220 LGSGTFGQVYLGFNSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQLCHPNIVQY 279
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
S L L V +EY+ GGS+ ++ + TE I +R+ L GL +LH + +HRD
Sbjct: 280 YGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLAYLHGRNTVHRD 339
Query: 818 IKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-SRKEYGPKVDIW 876
IK NIL+ NG+IKL DFG + + + G+PYWMAPEVV S+ Y VDIW
Sbjct: 340 IKGANILVDPNGEIKLADFGMAKHVTAFS-TMLSFKGSPYWMAPEVVMSQNGYTHAVDIW 398
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIA-TNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
SL PP+ + A++ I + TP++ P +LS+ F+ CL +P
Sbjct: 399 SLGCTILEMATSKPPWSQFEGVAAIFKIGNSKDTPEI--PDHLSNDAKNFIRLCLQRNPT 456
Query: 936 DRGTAADLLEDPFI 949
R TA+ LLE PF+
Sbjct: 457 VRPTASQLLEHPFL 470
>At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 520
Score = 135 bits (339), Expect = 4e-31
Identities = 91/284 (32%), Positives = 148/284 (52%), Gaps = 14/284 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVM-KGSKHNNIVNFIDSY 762
IG GAS V A + + +A+K++N+ ++ K++ ++ EI + + H +V+F ++
Sbjct: 89 IGSGASSVVQRAIHIPNHRILALKKINIFEREKRQQLLTEIRTLCEAPCHEGLVDFHGAF 148
Query: 763 LF--RGDLWVVMEYMEGGSLTDV--VTHCILTEGQIGAVSRETLKGLQFLHS-KGVIHRD 817
G + + +EYM GGSL D+ VT I E + ++ + L+GL +LH + ++HRD
Sbjct: 149 YSPDSGQISIALEYMNGGSLADILKVTKKI-PEPVLSSLFHKLLQGLSYLHGVRHLVHRD 207
Query: 818 IKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWS 877
IK N+L+++ G+ K+TDFG A + T VGT +M+PE + Y DIWS
Sbjct: 208 IKPANLLINLKGEPKITDFGISAGLENSMAMCATFVGTVTYMSPERIRNDSYSYPADIWS 267
Query: 878 LXXXXXXXXXXXPPYL-NETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
L PY+ NE P+ + I + +P S + F++ CL DP+
Sbjct: 268 LGLALFECGTGEFPYIANEGPVNLMLQILDDPSP-TPPKQEFSPEFCSFIDACLQKDPDA 326
Query: 937 RGTAADLLEDPFITEIAEENTSLAPLVK-----LARMKKLAESM 975
R TA LL PFIT+ +E LA V+ R+K LA+ +
Sbjct: 327 RPTADQLLSHPFITKHEKERVDLATFVQSIFDPTQRLKDLADML 370
>Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 620
Score = 134 bits (338), Expect = 5e-31
Identities = 92/258 (35%), Positives = 136/258 (52%), Gaps = 15/258 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQ-PKKELIVN----EILVMKGSKHNNIVNF 758
+GQGA G VY Y++ T +A+KQ+ + P+ VN EI ++K H IV +
Sbjct: 363 LGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQY 422
Query: 759 IDSYLFRGD--LWVVMEYMEGGSLTDVV-THCILTEGQIGAVSRETLKGLQFLHSKGVIH 815
+ L + MEYM GGS+ D + + LTE +R+ L+G+ +LHS ++
Sbjct: 423 YGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVL 482
Query: 816 RDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTM---VGTPYWMAPEVVSRKEYGPK 872
RDIK NIL G++KL DFG ++ + L T M GTPYWM+PEV+S + YG K
Sbjct: 483 RDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRK 542
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGT-PKLKDPGNLSHKMAMFLNWCLM 931
DIWS+ PP+ + A++ IAT T PKL P ++S FL +
Sbjct: 543 ADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKL--PPHVSDYTRDFLK-RIF 599
Query: 932 VDPEDRGTAADLLEDPFI 949
V+ + R +A +LL F+
Sbjct: 600 VEAKLRPSADELLRHMFV 617
>At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 134 bits (336), Expect = 9e-31
Identities = 84/267 (31%), Positives = 138/267 (51%), Gaps = 11/267 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIK--QMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDS 761
IG+G+SG V T A+K Q+N+++ +K I E+ + + S+ N+V S
Sbjct: 76 IGKGSSGVVQLVQHKWTGQFFALKVIQLNIDEAIRKA-IAQELKINQSSQCPNLVTSYQS 134
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLH-SKGVIHRDIK 819
+ G + +++EYM+GGSL D + + + + A+ R+ L+GL +LH + +IHRD+K
Sbjct: 135 FYDNGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLK 194
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
N+L++ G++K+TDFG + T VGT +M+PE + +YG K DIWSL
Sbjct: 195 PSNLLINHRGEVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVGNKYGNKSDIWSLG 254
Query: 880 XX----XXXXXXXXPPYLNETPLRALYLI--ATNGTPKLKDPGNLSHKMAMFLNWCLMVD 933
PP ET L+ + P GN S +++ F++ CL D
Sbjct: 255 LVVLECATGKFPYAPPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFISTCLQKD 314
Query: 934 PEDRGTAADLLEDPFITEIAEENTSLA 960
P R +A +L+E PF+ + +LA
Sbjct: 315 PNSRSSAKELMEHPFLNKYDYSGINLA 341
>At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 710
Score = 134 bits (336), Expect = 9e-31
Identities = 95/267 (35%), Positives = 126/267 (46%), Gaps = 17/267 (6%)
Query: 696 KLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNN 754
K YK + +IG GAS VY A L TN VAIK ++L++ + I E M H N
Sbjct: 31 KDYKLMEEIGHGASAVVYRAIYLPTNEVVAIKCLDLDRCNSNLDDIRRESQTMSLIDHPN 90
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI---LTEGQIGAVSRETLKGLQFLHSK 811
++ S+ LWVVM +M GS ++ E I V +ETLK L +LH +
Sbjct: 91 VIKSFCSFSVDHSLWVVMPFMAQGSCLHLMKTAYSDGFEESAICCVLKETLKALDYLHRQ 150
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYWMAPEVVS-RK 867
G IHRD+K+ NILL NG+IKL DFG A + + R T VGTP WMAPEV+
Sbjct: 151 GHIHRDVKAGNILLDDNGEIKLGDFGVSACLFDNGDRQRARNTFVGTPCWMAPEVLQPGN 210
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL---------KDPGNL 918
Y K DIWS P+ P++ L + N P L K +
Sbjct: 211 GYNSKADIWSFGITALELAHGHAPFSKYPPMKVLLMTIQNAPPGLDYDRDKKFSKRTFSC 270
Query: 919 SHKMAMFLNWCLMVDPEDRGTAADLLE 945
+ + CL+ D R TA LL+
Sbjct: 271 AQSFKEMVAMCLVKDQTKRPTAEKLLK 297
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 133 bits (335), Expect = 1e-30
Identities = 91/279 (32%), Positives = 149/279 (52%), Gaps = 19/279 (6%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK--------ELIVNEILVMKGSKHNNI 755
IG+G+ G VY + T +A+KQ+ + K + E + +E+ +K H NI
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNI 1240
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V ++ + +EY+ GGS+ ++ + E I ++ + LKGL +LHSKG++
Sbjct: 1241 VQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGIL 1300
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEV-NLKRTTMVGTPYWMAPEVVSRKE-YGPK 872
HRD+K+DN+LL +G K++DFG + ++ + TM GT +WMAPE+V K+ Y K
Sbjct: 1301 HRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAK 1360
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLI--ATNGTPKLKDPGNLSHKMAM-FLNWC 929
VDIWSL P+ N + A++ I + + P +D L ++ FL+ C
Sbjct: 1361 VDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDAC 1420
Query: 930 LMVDPEDRGTAADLLEDPFITEIAE----ENTSLAPLVK 964
++PE R TA +LL PF +E+ E ++T LA +K
Sbjct: 1421 FEINPEKRPTANELLSHPF-SEVNETFNFKSTRLAKFIK 1458
>SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1116
Score = 132 bits (333), Expect = 2e-30
Identities = 86/267 (32%), Positives = 140/267 (52%), Gaps = 24/267 (8%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK-------QPKKELIVN---EILVMKGSKHN 753
IG G G V+ A + T +A+KQ+ + + Q +K+++ + EI ++ H
Sbjct: 831 IGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADLDHL 890
Query: 754 NIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQ-IGAVSRETLKGLQFLHSKG 812
NIV ++ D+ + +EY+ GGS+ + + E Q + VSR+ L GL +LHSKG
Sbjct: 891 NIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLHSKG 950
Query: 813 VIHRDIKSDNILLSMNGDIKLTDFGFCAQINEV--NLKRTTMVGTPYWMAPEVV--SRKE 868
+IHRD+K+DN+L+ +G K++DFG + V N +M G+ +WMAPEV+ +
Sbjct: 951 IIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQG 1010
Query: 869 YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP------GNLSHKM 922
Y KVD+WSL P+ + ++A++ + GT K P +S +
Sbjct: 1011 YSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKL---GTEKKAPPIPSELVSQVSPEA 1067
Query: 923 AMFLNWCLMVDPEDRGTAADLLEDPFI 949
FLN C V+ + R TA +LL PF+
Sbjct: 1068 IQFLNACFTVNADVRPTAEELLNHPFM 1094
>Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1191
Score = 132 bits (332), Expect = 3e-30
Identities = 77/188 (40%), Positives = 104/188 (54%), Gaps = 9/188 (4%)
Query: 772 MEYMEGGSLTDVVTHC---ILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILLSMN 828
ME+ GS+TD+V + L E I + RE L+GL LH+ VIHRDIK N+LL+ N
Sbjct: 1 MEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTEN 60
Query: 829 GDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE-----YGPKVDIWSLXXXXX 883
++KL DFG AQ++ +R T +GTPYWMAPEV++ E Y + DIWSL
Sbjct: 61 AEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAI 120
Query: 884 XXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADL 943
PP + P+RAL+LI N P+LK S K F++ CL+ R L
Sbjct: 121 EMAEGAPPLCDMHPMRALFLIPRNPPPRLKSK-KWSKKFIDFIDTCLIKTYLSRPPTEQL 179
Query: 944 LEDPFITE 951
L+ PFI +
Sbjct: 180 LKFPFIRD 187
>At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 693
Score = 132 bits (332), Expect = 3e-30
Identities = 92/274 (33%), Positives = 128/274 (46%), Gaps = 17/274 (6%)
Query: 696 KLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNN 754
K YK + ++G GAS V+ A L TN VAIK ++L++ + I E M H N
Sbjct: 25 KDYKLMEEVGYGASAVVHRAIYLPTNEVVAIKSLDLDRCNSNLDDIRREAQTMTLIDHPN 84
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI---LTEGQIGAVSRETLKGLQFLHSK 811
++ S+ LWVVM +M GS ++ E I ++ +ETLK L +LH +
Sbjct: 85 VIKSFCSFAVDHHLWVVMPFMAQGSCLHLMKAAYPDGFEEAAICSMLKETLKALDYLHRQ 144
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYWMAPEVVS-RK 867
G IHRD+K+ NILL G+IKL DFG A + + R T VGTP WMAPEV+
Sbjct: 145 GHIHRDVKAGNILLDDTGEIKLGDFGVSACLFDNGDRQRARNTFVGTPCWMAPEVLQPGS 204
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL---------KDPGNL 918
Y K DIWS P+ P++ L + N P L K +
Sbjct: 205 GYNSKADIWSFGITALELAHGHAPFSKYPPMKVLLMTIQNAPPGLDYDRDKKFSKKMSSC 264
Query: 919 SHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEI 952
+ + CL+ D R TA LL+ F +
Sbjct: 265 AQSFKELVALCLVKDQTKRPTAEKLLKHSFFKNV 298
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 130 bits (328), Expect = 8e-30
Identities = 83/254 (32%), Positives = 131/254 (50%), Gaps = 5/254 (1%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
Y L IG+G+ G VY + VA+K + + +KEL + EI +M+G +H NI
Sbjct: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNI 63
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIH 815
V+ +DS+ ++ VV +Y EG + L E Q+ A++ + + L +LHS ++H
Sbjct: 64 VHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILH 123
Query: 816 RDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDI 875
RD+K NILL+ G IKL DFGF ++ + T++ GTP +M+PE+V + Y D+
Sbjct: 124 RDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADL 183
Query: 876 WSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
WS+ PP+ + + + LI + ++ P +S FL L DP
Sbjct: 184 WSVGCILYELAVGTPPFYATSIFQLVSLILKD---PVRWPSTISPCFKNFLQGLLTKDPR 240
Query: 936 DRGTAADLLEDPFI 949
R + DLL PFI
Sbjct: 241 QRLSWPDLLYHPFI 254
>YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1331
Score = 130 bits (327), Expect = 1e-29
Identities = 88/276 (31%), Positives = 136/276 (48%), Gaps = 25/276 (9%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKE----LIVNEILVMKGSKHNNIVNFI 759
IG G G VY+A L +A+K++ + + LI E+ V++ H NIV +
Sbjct: 1040 IGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYY 1099
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAV-SRETLKGLQFLHSKGVIHRDI 818
+ R + + MEY EGGSL ++ H + + + V + E L+GL +LH GV+HRDI
Sbjct: 1100 GVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDI 1159
Query: 819 KSDNILLSMNGDIKLTDFGFC-------------AQINEVNLKRTT---MVGTPYWMAPE 862
K +NILL NG IK DFG A + + ++ + M+GTP +MAPE
Sbjct: 1160 KPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPE 1219
Query: 863 VVSRKEYGPKV---DIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDPGNL 918
+S K+ D+W+L P+ N + +Y +A P+L + +
Sbjct: 1220 TISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEM 1279
Query: 919 SHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAE 954
+ FL CL+ DP R TA +LL DP++ +I E
Sbjct: 1280 TAAGRAFLERCLVQDPTMRATAVELLIDPWMIQIRE 1315
>At4g08480 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 773
Score = 129 bits (325), Expect = 2e-29
Identities = 88/295 (29%), Positives = 153/295 (51%), Gaps = 20/295 (6%)
Query: 683 SKLTEICTTGDP-SKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK---- 737
S + IC +G + ++ + QG+ G VY A + A+K+++L Q +
Sbjct: 485 SNTSPICVSGGSINTSWQKGQLLRQGSFGSVYEAISEDGDF-FAVKEVSLLDQGSQAQEC 543
Query: 738 -ELIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGA 796
+ + EI ++ +H NI+ + + +L++ +E + GSL ++ + + I
Sbjct: 544 IQQLEGEIALLSQLEHQNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRYQIRDSLISL 603
Query: 797 VSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFC--AQINEVNLKRTTMVG 854
+++ L GL++LH KG IHRDIK IL+ NG +KL DFG +++N++ ++ T+
Sbjct: 604 YTKQILDGLKYLHHKGFIHRDIKCATILVDANGTVKLADFGLAKVSKLNDIKSRKETL-- 661
Query: 855 TPYWMAPEVVSRKE---YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPK 911
+WMAPEV++RK+ Y DIWSL PY + P+ AL+ I P+
Sbjct: 662 --FWMAPEVINRKDNDGYRSPADIWSLGCTVLEMCTGQIPYSDLEPVEALFRIRRGTLPE 719
Query: 912 LKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITE--IAEENTSLAPLVK 964
+ P LS F+ CL ++PE+R TA +LL PF+ + + S +PL++
Sbjct: 720 V--PDTLSLDARHFILKCLKLNPEERPTATELLNHPFVRRPLPSSGSGSTSPLIR 772
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 129 bits (323), Expect = 3e-29
Identities = 78/254 (30%), Positives = 127/254 (49%), Gaps = 5/254 (1%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFIDS 761
+G+G+ G VY T +VA+K + + + K++ + EI +++ KH NI+ +DS
Sbjct: 12 VGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLKHENIIEMLDS 71
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSD 821
+ + VV E+ +G + L E Q+ A++++ +K L +LHS +IHRD+K
Sbjct: 72 FENAREFCVVTEFAQGELFEILEDDKCLPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQ 131
Query: 822 NILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXX 881
NIL+ +KL DFGF ++ + ++ GTP +MAPE+V + Y VD+WSL
Sbjct: 132 NILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVKEQPYDRTVDLWSLGVI 191
Query: 882 XXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAA 941
PP+ + + I + +K P +S FL L +P R T
Sbjct: 192 LYELYVGQPPFYTNSVYALIRHIVKD---PVKYPDEMSTYFESFLKGLLNKEPHSRLTWP 248
Query: 942 DLLEDPFITEIAEE 955
L E PF+ E EE
Sbjct: 249 ALREHPFVKETQEE 262
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 128 bits (322), Expect = 4e-29
Identities = 78/255 (30%), Positives = 127/255 (49%), Gaps = 7/255 (2%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYL 763
+G+G G VY A + T +AIK++ + + + EI + +H NIV ++ S
Sbjct: 585 LGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLRHRNIVRYLGSCS 644
Query: 764 FRGDLWVVMEYMEGGSLTDVVT----HCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
G + ME + GGSL+D++ E + S++ L+GL++LH + ++HRDIK
Sbjct: 645 ENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIK 704
Query: 820 SDNILL-SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR--KEYGPKVDIW 876
DN+L+ + +G +K++DFG ++ +N T GT +MAPEV+ + + YGP DIW
Sbjct: 705 GDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAPEVIDQGVRGYGPAADIW 764
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S PP++ A P LS F+ C + D
Sbjct: 765 SFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMD 824
Query: 937 RGTAADLLEDPFITE 951
R +A+ LLEDPF+ +
Sbjct: 825 RPSASQLLEDPFLQD 839
>CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1228
Score = 128 bits (321), Expect = 5e-29
Identities = 79/270 (29%), Positives = 135/270 (49%), Gaps = 18/270 (6%)
Query: 694 PSKLYKNLI---------KIGQGASGGVYTAYE-LGTNASVAIKQMNLEKQPKKELIVNE 743
PS +Y N+ ++G GA G V A A K + +++ + E + E
Sbjct: 21 PSYIYDNVNPRDHWNIIGELGDGAFGKVEKAVSRTDPKLFAASKSIEIQEGEELEDFLVE 80
Query: 744 ILVMKGSK-HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC--ILTEGQIGAVSRE 800
I ++ K H ++ +Y F L +++E+ GG++ +++ +L E QI +
Sbjct: 81 IEILSECKGHPVMLGLYSTYFFENKLTMLLEFCGGGAVDNIIVELGHVLKEDQIRYIGYY 140
Query: 801 TLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMA 860
L++LHS+ VIHRD+K+ NILL+ +G ++L DFG A++ KR T +GTPYWMA
Sbjct: 141 VCDALKWLHSQNVIHRDLKAGNILLTQDGQVRLADFGVSAKLKSEREKRDTFIGTPYWMA 200
Query: 861 PEVVS-----RKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP 915
PEV++ + Y DIWS PP+ + + +R + + + P L P
Sbjct: 201 PEVMACETFKDQPYDCISDIWSFGITLIEMAQGEPPHSDVSVMRVIIKVQKSEPPTLLQP 260
Query: 916 GNLSHKMAMFLNWCLMVDPEDRGTAADLLE 945
+ + + L CL+ DP +R AA++ +
Sbjct: 261 SHWTRSFSDILTRCLVKDPRNRPPAAEIFK 290
>At1g70430 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 594
Score = 128 bits (321), Expect = 5e-29
Identities = 96/296 (32%), Positives = 139/296 (46%), Gaps = 28/296 (9%)
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHN 753
+K Y+ ++G+G S VY A + N VA+K ++LEK + E I E+ +M H
Sbjct: 13 AKDYELFEEVGEGVSATVYRARCIALNEIVAVKILDLEKCRNDLETIRKEVHIMSLIDHP 72
Query: 754 NIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI---LTEGQIGAVSRETLKGLQFLHS 810
N++ S++ LW+VM YM GGS ++ L + I + RE LK L +LH
Sbjct: 73 NLLKAHCSFIDSSSLWIVMPYMSGGSCFHLMKSVYPEGLEQPIIATLLREVLKALVYLHR 132
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRK 867
+G IHRD+K+ NIL+ G +KL DFG A E R T VGTP WMAPEV+ +
Sbjct: 133 QGHIHRDVKAGNILIHSKGVVKLGDFGVSACMFDSGERMQTRNTFVGTPCWMAPEVMQQL 192
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL--KDPGNLSHKMAMF 925
+ P+ P++ L + N P+L S
Sbjct: 193 D----------GYDFKYLAHGHAPFSKYPPMKVLLMTLQNAPPRLDYDRDKKFSKSFREL 242
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEEN-------TSLAPLVKLARMKKLAES 974
+ CL+ DP+ R TAA LL+ PF + L+PL + R KKL E+
Sbjct: 243 IAACLVKDPKKRPTAAKLLKHPFFKHARSTDYLSRKILHGLSPLGE--RFKKLKEA 296
>YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1579
Score = 127 bits (320), Expect = 7e-29
Identities = 86/292 (29%), Positives = 137/292 (46%), Gaps = 41/292 (14%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKE----LIVNEILVMKGSKHNNIVNFI 759
IG G G VY+A +L +A+K++N++ + LI E+ V++ H NIV++
Sbjct: 1272 IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYY 1331
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAV-SRETLKGLQFLHSKGVIHRDI 818
+ R + + MEY EGGSL ++ H + + + V + + L+GL +LH G++HRD+
Sbjct: 1332 GVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDV 1391
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTT--------------------------- 851
K +NILL NG IK DFG +I + +
Sbjct: 1392 KPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNE 1451
Query: 852 -----MVGTPYWMAPEVVSRKEYGPKV---DIWSLXXXXXXXXXXXPPYLN-ETPLRALY 902
M+GTP +MAPE ++ K+ D+WSL P+ N + +Y
Sbjct: 1452 NALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMY 1511
Query: 903 LIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAE 954
+A TP+ +S FL CL+ +P R +A +LL DP+I +I E
Sbjct: 1512 HVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWIVQIRE 1563
>At4g08470 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 560
Score = 127 bits (318), Expect = 1e-28
Identities = 80/258 (31%), Positives = 130/258 (50%), Gaps = 15/258 (5%)
Query: 704 IGQGASGGVYTAY----ELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFI 759
+G+G+ VY A + V++ ++ Q + + EI ++ +H NIV +
Sbjct: 309 LGRGSYASVYEAISEDGDFFAVKEVSLLDKGIQAQECIQQLEGEIALLSQLQHQNIVRYR 368
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+ L++ +E + GS+ + L+ + +R+ L GL +LH KG +HRDIK
Sbjct: 369 GTAKDVSKLYIFLELVTQGSVQKLYERYQLSYTVVSLYTRQILAGLNYLHDKGFVHRDIK 428
Query: 820 SDNILLSMNGDIKLTDFGF--CAQINEVNLKRTTMVGTPYWMAPEVVSRKE---YGPKVD 874
N+L+ NG +KL DFG ++ N++ + GT +WMAPEV++RK+ G D
Sbjct: 429 CANMLVDANGTVKLADFGLAEASKFNDI----MSCKGTLFWMAPEVINRKDSDGNGSPAD 484
Query: 875 IWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDP 934
IWSL PY + P++A + I P + P LS F+ CL V+P
Sbjct: 485 IWSLGCTVLEMCTGQIPYSDLKPIQAAFKIGRGTLPDV--PDTLSLDARHFILTCLKVNP 542
Query: 935 EDRGTAADLLEDPFITEI 952
E+R TAA+LL PF+ +
Sbjct: 543 EERPTAAELLHHPFVINL 560
>CE27177 [T] KOG4279 Serine/threonine protein kinase
Length = 1378
Score = 126 bits (317), Expect = 1e-28
Identities = 77/260 (29%), Positives = 137/260 (52%), Gaps = 14/260 (5%)
Query: 702 IKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDS 761
+ +G+G G VY A ++ T + +K++ ++ + + ++ EI + H NIV ++
Sbjct: 668 VVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGC 727
Query: 762 YLFRGD-----LWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHSKGVI 814
L D + ME++ GGSL+ ++ + E + ++ L+GL++LH ++
Sbjct: 728 DLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIV 787
Query: 815 HRDIKSDNILL-SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV--SRKEYGP 871
HRDIK DN+L+ + +G K++DFG C ++ +N T GT +MAPEV+ ++ YG
Sbjct: 788 HRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVIDHGQRGYGA 847
Query: 872 KVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGT-PKLKDPGNLSHKMAMFLNWC 929
DIWS PP++ + P A++ + T P + P ++ K F+ C
Sbjct: 848 PADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPI--PTEITEKCRNFIKSC 905
Query: 930 LMVDPEDRGTAADLLEDPFI 949
+ + DR +A DLL+DPFI
Sbjct: 906 FLPEACDRPSAKDLLQDPFI 925
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 126 bits (316), Expect = 2e-28
Identities = 87/275 (31%), Positives = 140/275 (50%), Gaps = 15/275 (5%)
Query: 694 PSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNL--------EKQPKKELIVNEIL 745
PS ++ IG GA G VY L + +AIKQ+ + + Q + E+
Sbjct: 64 PSIRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQ 123
Query: 746 VMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKG 804
++K H NIV ++ + L ++ME++ GGS++ ++ E I +++ L G
Sbjct: 124 LLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLG 183
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKR--TTMVGTPYWMAPE 862
L++LH+ G++HRDIK NIL+ G I+L DFG ++ E+ +M GTPYWMAPE
Sbjct: 184 LEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPE 243
Query: 863 VVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRA--LYLIATNGTPKLKDPGNLSH 920
V+ + + DIWS+ PP+ + A L++ T P + P +LS
Sbjct: 244 VILQTGHSFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHPPI--PEDLSP 301
Query: 921 KMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEE 955
+ FL CL +P R +A +LL+ PF+T +E
Sbjct: 302 EAKDFLMKCLHKEPSLRLSATELLQHPFVTGKRQE 336
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 125 bits (315), Expect = 2e-28
Identities = 81/290 (27%), Positives = 139/290 (47%), Gaps = 18/290 (6%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK----QPKKELIVNEILVMKGSKHNNIVNFI 759
+ G G VYT + T +A+K++ L+ + + I NE+ V++ H N+V +
Sbjct: 1043 VRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYY 1102
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ R +++ ME+ +GGSL D++ H I E + + L+GL ++HS+ ++HRDI
Sbjct: 1103 GVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDI 1162
Query: 819 KSDNILLSMNGDIKLTDFGFCAQIN----------EVNLKRTTMVGTPYWMAPEVVSRKE 868
K NILL G IK +DFG ++ ++ + + GTP +MAPE++ +
Sbjct: 1163 KPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEIILGTK 1222
Query: 869 YGP--KVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDPGNLSHKMAMF 925
G +DIWSL P+ + +Y +A TP + +S F
Sbjct: 1223 KGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQNEKISSLARDF 1282
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAESM 975
+ C DPE R A DLL P+IT+ ++ P + + L+ ++
Sbjct: 1283 IEQCFERDPEQRPRAVDLLTHPWITDFRKKTIITMPPATITKKTSLSHTI 1332
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 125 bits (315), Expect = 2e-28
Identities = 79/257 (30%), Positives = 133/257 (51%), Gaps = 11/257 (4%)
Query: 702 IKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDS 761
+ +G+G G VY +L +AIK++ + + EI + K KH NIV ++ S
Sbjct: 684 VVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGS 743
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTH----CILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
+ G + + ME + GGSL+ ++ E IG +++ L+GL++LH ++HRD
Sbjct: 744 FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803
Query: 818 IKSDNILL-SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR--KEYGPKVD 874
IK DN+L+ + +G +K++DFG ++ +N T GT +MAPE++ + + YG D
Sbjct: 804 IKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAAD 863
Query: 875 IWSLXXXXXXXXXXXPPYLN-ETPLRALYLIAT-NGTPKLKDPGNLSHKMAMFLNWCLMV 932
IWSL PP+ P A++ + P++ P ++S + F+ C
Sbjct: 864 IWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEI--PESMSAEAKAFILKCFEP 921
Query: 933 DPEDRGTAADLLEDPFI 949
DP+ R A DLL D F+
Sbjct: 922 DPDKRACANDLLVDEFL 938
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 125 bits (315), Expect = 2e-28
Identities = 85/268 (31%), Positives = 137/268 (50%), Gaps = 15/268 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQM----NLEKQPKKELIVNE----ILVMKGSKHNNI 755
IG+GA G VY L + +A+KQ+ N + K + + E + ++K H NI
Sbjct: 75 IGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNI 134
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVI 814
V ++ + L +++E++ GGS++ ++ E + +R+ L GL++LH+ ++
Sbjct: 135 VRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIM 194
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLK--RTTMVGTPYWMAPEVVSRKEYGPK 872
HRDIK NIL+ G IKL DFG Q+ E+ +M GTPYWMAPEV+ + +
Sbjct: 195 HRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFS 254
Query: 873 VDIWSLXXXXXXXXXXXPPYLNE-TPLRALYLIATNGT-PKLKDPGNLSHKMAMFLNWCL 930
DIWS+ P+ + + A++ I T + P + P LS FL CL
Sbjct: 255 ADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPI--PDTLSSDAKDFLLKCL 312
Query: 931 MVDPEDRGTAADLLEDPFITEIAEENTS 958
P R TA++LL+ PF+ +E+ S
Sbjct: 313 QEVPNLRPTASELLKHPFVMGKHKESAS 340
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 125 bits (314), Expect = 3e-28
Identities = 82/270 (30%), Positives = 132/270 (48%), Gaps = 11/270 (4%)
Query: 691 TGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNL-----EKQPKKELIVNEIL 745
T P +K +G G+ G VY + + A+K++ L + + + + EI
Sbjct: 393 TVSPGSRWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEIS 452
Query: 746 VMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKG 804
V+ +H NIV + S L++ +EY+ GGS+ ++ + E I +++ L G
Sbjct: 453 VLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENAIRNYTQQILSG 512
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV 864
L +LH+K +HRDIK NIL+ +G +K+ DFG I + G+PYWMAPEV+
Sbjct: 513 LAYLHAKNTVHRDIKGANILVDPHGRVKVADFGMAKHIT-AQSGPLSFKGSPYWMAPEVI 571
Query: 865 SRKE-YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKD-PGNLSHKM 922
VDIWSL PP+ + A++ I + +L D P +LS +
Sbjct: 572 KNSNGSNLAVDIWSLGCTVLEMATTKPPWSQYEGVPAMFKI--GNSKELPDIPDHLSEEG 629
Query: 923 AMFLNWCLMVDPEDRGTAADLLEDPFITEI 952
F+ CL +P +R TAA LL+ F+ +
Sbjct: 630 KDFVRKCLQRNPANRPTAAQLLDHAFVRNV 659
>At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 356
Score = 124 bits (312), Expect = 6e-28
Identities = 82/270 (30%), Positives = 131/270 (48%), Gaps = 10/270 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIK--QMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDS 761
IG+G+ G V A+K QMN++++ +K+++ + S+ ++V S
Sbjct: 76 IGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQASSQCPHVVVCYHS 135
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHS-KGVIHRDIK 819
+ G +V+EYM+ GSL DV+ + E + V ++ L GL +LH+ + VIHRDIK
Sbjct: 136 FYHNGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIK 195
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
N+L++ G++K++DFG A + +R T VGT +M+PE +S Y DIWSL
Sbjct: 196 PSNLLVNHKGEVKISDFGVSASLASSMGQRDTFVGTYNYMSPERISGSTYDYSSDIWSLG 255
Query: 880 XXXXXXXXXXPPYL------NETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVD 933
PYL N L P S + F++ C+ D
Sbjct: 256 MSVLECAIGRFPYLESEDQQNPPSFYELLAAIVENPPPTAPSDQFSPEFCSFVSACIQKD 315
Query: 934 PEDRGTAADLLEDPFITEIAEENTSLAPLV 963
P R ++ DLL PFI + +++ L LV
Sbjct: 316 PPARASSLDLLSHPFIKKFEDKDIDLGILV 345
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 124 bits (310), Expect = 9e-28
Identities = 86/288 (29%), Positives = 134/288 (45%), Gaps = 15/288 (5%)
Query: 691 TGDPSKLYKNLIKIGQGASGGVYT----AYELGTNASVAIKQMNLEKQPKKE-LIVNEIL 745
T D +L ++G+ GG Y A + TN A K MN + KK+ + NEI
Sbjct: 20 TVDQKQLLPCKYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIA 79
Query: 746 VMK--GSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETL 802
++K +H NI++ +D + +L+++ E GG L D + E A+ R T
Sbjct: 80 ILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTT 139
Query: 803 KGLQFLHSKGVIHRDIKSDNILLSM---NGDIKLTDFGFCAQINEVNLKRT-TMVGTPYW 858
+++LH G++HRD+K +N+L N D+ + DFG + T GTP +
Sbjct: 140 SAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEY 199
Query: 859 MAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--G 916
MAPEV R YG VD+W++ P+ + + + I N DP
Sbjct: 200 MAPEVFRRTGYGKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILAN-EYTFNDPCWS 258
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
+S F+ CL DP R TAAD L+ PF++E ++L P V+
Sbjct: 259 GISETAKDFIKKCLENDPSKRLTAADALKHPFLSEKRPATSNLLPNVR 306
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 124 bits (310), Expect = 9e-28
Identities = 85/267 (31%), Positives = 135/267 (49%), Gaps = 21/267 (7%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFID 760
KIG+G G VYT + T +A+K++ + K + +E+ + +G KH N+V +
Sbjct: 1298 KIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNLVRYFG 1357
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
L R ++++ MEY + G+L +V + L E I S++ + LH G++HRDIK
Sbjct: 1358 VELHREEMYIFMEYCDEGTLEEV-SRLGLQEHVIRLYSKQITIAINVLHEHGIVHRDIKG 1416
Query: 821 DNILLSMNGDIKLTDFGFCAQI--------NEVNLKRTTMVGTPYWMAPEVVSRKE---Y 869
NI L+ +G IKL DFG ++ EVN + +GT +MAPEV++R + +
Sbjct: 1417 ANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVN----STLGTAAYMAPEVITRAKGEGH 1472
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNW 928
G DIWSL P+ E + +Y + P + P LS + FL+
Sbjct: 1473 GRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPI--PERLSPEGKDFLSH 1530
Query: 929 CLMVDPEDRGTAADLLEDPFITEIAEE 955
CL DP+ R TA+ LL+ F+ +E
Sbjct: 1531 CLESDPKMRWTASQLLDHSFVKVCTDE 1557
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 124 bits (310), Expect = 9e-28
Identities = 85/267 (31%), Positives = 135/267 (49%), Gaps = 21/267 (7%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFID 760
KIG+G G VYT + T +A+K++ + K + +E+ + +G KH N+V +
Sbjct: 1347 KIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNLVRYFG 1406
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
L R ++++ MEY + G+L +V + L E I S++ + LH G++HRDIK
Sbjct: 1407 VELHREEMYIFMEYCDEGTLEEV-SRLGLQEHVIRLYSKQITIAINVLHEHGIVHRDIKG 1465
Query: 821 DNILLSMNGDIKLTDFGFCAQI--------NEVNLKRTTMVGTPYWMAPEVVSRKE---Y 869
NI L+ +G IKL DFG ++ EVN + +GT +MAPEV++R + +
Sbjct: 1466 ANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVN----STLGTAAYMAPEVITRAKGEGH 1521
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNW 928
G DIWSL P+ E + +Y + P + P LS + FL+
Sbjct: 1522 GRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPI--PERLSPEGKDFLSH 1579
Query: 929 CLMVDPEDRGTAADLLEDPFITEIAEE 955
CL DP+ R TA+ LL+ F+ +E
Sbjct: 1580 CLESDPKMRWTASQLLDHSFVKVCTDE 1606
>At5g66850 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 124 bits (310), Expect = 9e-28
Identities = 83/261 (31%), Positives = 126/261 (47%), Gaps = 19/261 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL-----IVNEILVMKGSKHNNIVNF 758
IG+G G VY A T A A+K++ L K + EI ++ +H NIV +
Sbjct: 11 IGRGTFGSVYVASNSETGALCAMKEVELFPDDPKSAECIKQLEQEIKLLSNLQHPNIVQY 70
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVT-HC-ILTEGQIGAVSRETLKGLQFLHSKGVIHR 816
S ++ +EY+ GS+ + HC +TE + +R L GL +LH+K +HR
Sbjct: 71 FGSETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTRHILSGLAYLHNKKTVHR 130
Query: 817 DIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV----VSRKEYGP- 871
DIK N+L+ +G +KL DFG + ++ G+PYWMAPEV V +K+ P
Sbjct: 131 DIKGANLLVDASGVVKLADFGMAKHLTGQRAD-LSLKGSPYWMAPEVLMQAVMQKDSNPD 189
Query: 872 ---KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNW 928
VDIWSL PP+ A++ + + P P ++S + FL
Sbjct: 190 LAFAVDIWSLGCTIIEMFTGKPPWSEFEGAAAMFKVMRDSPP---IPESMSPEGKDFLRL 246
Query: 929 CLMVDPEDRGTAADLLEDPFI 949
C +P +R TA+ LLE F+
Sbjct: 247 CFQRNPAERPTASMLLEHRFL 267
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 122 bits (307), Expect = 2e-27
Identities = 84/250 (33%), Positives = 132/250 (52%), Gaps = 11/250 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN---EILVMKGSKHNNIVNFID 760
+G G VY A + TN SVAIK ++ EK K LI + EI +++ +H NIV +
Sbjct: 32 LGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVRHPNIVQLFE 91
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ VMEY+ GG L + V L E ++ + + F H++GV HRD+K
Sbjct: 92 VMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQLISAVTFCHARGVYHRDLKP 151
Query: 821 DNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+LL NG++K++DFG A QI + L T GTP ++APEV++RK Y KVDIW
Sbjct: 152 ENLLLDENGNLKVSDFGLSAVSDQIRQDGLFH-TFCGTPAYVAPEVLARKGYDAAKVDIW 210
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S P+ ++ + A+Y G + + P S ++ L+ L +PE
Sbjct: 211 SCGVILFVLMAGYLPF-HDRNVMAMYKKIYRG--EFRCPRWFSTELTRLLSKLLETNPEK 267
Query: 937 RGTAADLLED 946
R T +++E+
Sbjct: 268 RFTFPEIMEN 277
>At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 422
Score = 122 bits (306), Expect = 3e-27
Identities = 85/257 (33%), Positives = 127/257 (49%), Gaps = 22/257 (8%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-----ELIVNEILVMKGSKHNNIVNF 758
+G+G+ G VY + A K+++L Q + + + I ++ +H NIV +
Sbjct: 159 LGRGSLGSVYEGISADGDF-FAFKEVSLLDQGSQAHEWIQQVEGGIALLSQLQHQNIVRY 217
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ +L++ +E + GSL + L + + +R+ L GL++LH KG IHR+I
Sbjct: 218 RGTTKDESNLYIFLELVTQGSLRKLYQRNQLGDSVVSLYTRQILDGLKYLHDKGFIHRNI 277
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPY--WMAPEVVSRKE----YGPK 872
K N+L+ NG +KL DFG K ++ TPY WMAPEV+ + YG
Sbjct: 278 KCANVLVDANGTVKLADFGLA--------KVMSLWRTPYWNWMAPEVILNPKDYDGYGTP 329
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMV 932
DIWSL PY + ALY I T PK+ P LS F+ CL V
Sbjct: 330 ADIWSLGCTVLEMLTGQIPYSDLEIGTALYNIGTGKLPKI--PDILSLDARDFILTCLKV 387
Query: 933 DPEDRGTAADLLEDPFI 949
+PE+R TAA+LL PF+
Sbjct: 388 NPEERPTAAELLNHPFV 404
>7300409 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 511
Score = 121 bits (304), Expect = 5e-27
Identities = 84/265 (31%), Positives = 118/265 (43%), Gaps = 58/265 (21%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNNIVNFIDSY 762
IG GA+ V+ AY + N AIK++NLEK + ++ EI M H N+V + S+
Sbjct: 44 IGVGATAVVHGAYCIPRNEKCAIKRINLEKWNTSMDELLKEIQAMSSCFHENVVTYHTSF 103
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCILT---------EGQIGAVSRETLKGLQFLHSKGV 813
+ R +LW+V+ +EGGSL D++ H + T E I V +E LKGL++ HS G
Sbjct: 104 VVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQ 163
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKV 873
IHRDIK+ NIL+ +G I++ DFG
Sbjct: 164 IHRDIKAGNILIGDDGTIQIADFG-----------------------------------A 188
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKL----------KDPGNLSHKMA 923
DIWS PY P++ L L N P L K G KM
Sbjct: 189 DIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMI 248
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPF 948
+ CL +P R TA++LL+ F
Sbjct: 249 V---ECLQKEPSKRPTASELLKHAF 270
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 121 bits (303), Expect = 6e-27
Identities = 81/262 (30%), Positives = 135/262 (50%), Gaps = 15/262 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNL--------EKQPKKELIVNEILVMKGSKHNNI 755
IG+GA G VY L + +A+KQ+ + + Q + + E+ ++K H NI
Sbjct: 74 IGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNI 133
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVI 814
V ++ + L +++E++ GGS++ ++ E + + + L GL++LH+ ++
Sbjct: 134 VRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIM 193
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNL--KRTTMVGTPYWMAPEVVSRKEYGPK 872
HRDIK NIL+ G IKL DFG Q+ E+ +M GTPYWMAPEV+ + +
Sbjct: 194 HRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFS 253
Query: 873 VDIWSLXXXXXXXXXXXPPYLNE-TPLRALYLIATNGT-PKLKDPGNLSHKMAMFLNWCL 930
DIWS+ P+ + + A++ I T + P + P N+S FL CL
Sbjct: 254 ADIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTKSHPPI--PDNISSDANDFLLKCL 311
Query: 931 MVDPEDRGTAADLLEDPFITEI 952
+P R TA++LL+ + T+I
Sbjct: 312 QQEPNLRPTASELLKVKWSTDI 333
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 119 bits (298), Expect = 2e-26
Identities = 83/277 (29%), Positives = 129/277 (45%), Gaps = 9/277 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYL 763
+G GA V+ + T A+K + + + NEI V+K KH NIV D Y
Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYE 88
Query: 764 FRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDN 822
++VM+ + GG L D ++ + TE V ++ L +++LH G++HRD+K +N
Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPEN 148
Query: 823 ILL---SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
+L N I +TDFG E N +T GTP ++APEV+++K Y VD WS+
Sbjct: 149 LLYLTPEENSKIMITDFGLSKM--EQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIG 206
Query: 880 XXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAMFLNWCLMVDPEDR 937
PP+ ET + L+ G + + P ++S F+ L DP +R
Sbjct: 207 VITYILLCGYPPFYEETESK-LFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNER 265
Query: 938 GTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAES 974
T L P+I + + P V L K A+S
Sbjct: 266 YTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAKS 302
>Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 448
Score = 119 bits (297), Expect = 3e-26
Identities = 78/267 (29%), Positives = 134/267 (49%), Gaps = 14/267 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPK-KELIVNEILVMKGSKHNNIVNFIDSY 762
+G G G VY AY + + +A+K + L+ + ++ I++E+ ++ + I+ F ++
Sbjct: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAF 231
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDN 822
+ + E+M+GGSL DV + E +G ++ +KGL +L S ++HRD+K N
Sbjct: 232 FVENRISICTEFMDGGSL-DVYRK--MPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSN 288
Query: 823 ILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXX 882
+L++ G +KL DFG Q+ VN T VGT +MAPE +S ++YG D+WSL
Sbjct: 289 MLVNTRGQVKLCDFGVSTQL--VNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISF 346
Query: 883 XXXXXXXPPYL-------NETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
PY + PL+ L I +P L G S F+ C+ P+
Sbjct: 347 MELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVL-PVGEFSEPFVHFITQCMRKQPK 405
Query: 936 DRGTAADLLEDPFITEIAEENTSLAPL 962
+R +L+ PFI + + N ++ +
Sbjct: 406 ERPAPEELMGHPFIVQFNDGNAAVVSM 432
>Hs22065797 [T] KOG0577 Serine/threonine protein kinase
Length = 897
Score = 118 bits (296), Expect = 4e-26
Identities = 72/182 (39%), Positives = 99/182 (53%), Gaps = 9/182 (4%)
Query: 772 MEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGD 830
MEY G + + H L E +I A++ L+GL +LHS +IHRDIK+ NILL+ G
Sbjct: 1 MEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQ 60
Query: 831 IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV---SRKEYGPKVDIWSLXXXXXXXXX 887
+KL DFG + + N + VGTPYWMAPEV+ +Y KVD+WSL
Sbjct: 61 VKLADFGSASMASPAN----SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAE 116
Query: 888 XXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDP 947
PP N + ALY IA N +P L+ S F++ CL P+DR T+ +LL+
Sbjct: 117 RKPPLFNMNAMSALYHIAQNESPTLQS-NEWSDYFRNFVDSCLQKIPQDRPTSEELLKHI 175
Query: 948 FI 949
F+
Sbjct: 176 FV 177
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 118 bits (295), Expect = 5e-26
Identities = 85/278 (30%), Positives = 135/278 (47%), Gaps = 23/278 (8%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
Y+ L IG+G V A + T VA+K ++ + L + E+ +MK H NI
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNI 79
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V + L++VMEY GG + D +V H + E + A R+ + +Q+ H K ++
Sbjct: 80 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV 139
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL + +IK+ DFGF + N K T G+P + APE+ K+Y GP+V
Sbjct: 140 HRDLKAENLLLDADMNIKIADFGFSNEFTFGN-KLDTFCGSPPYAAPELFQGKKYDGPEV 198
Query: 874 DIWSLXXXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
D+WSL P+ L E LR Y I P +S L
Sbjct: 199 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI----------PFYMSTDCENLL 248
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
L+++P RGT +++D ++ + E+ L P V+
Sbjct: 249 KKFLILNPSKRGTLEQIMKDRWM-NVGHEDDELKPYVE 285
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 118 bits (295), Expect = 5e-26
Identities = 85/278 (30%), Positives = 135/278 (47%), Gaps = 23/278 (8%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
Y+ L IG+G V A + T VA+K ++ + L + E+ +MK H NI
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNI 79
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V + L++VMEY GG + D +V H + E + A R+ + +Q+ H K ++
Sbjct: 80 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV 139
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL + +IK+ DFGF + N K T G+P + APE+ K+Y GP+V
Sbjct: 140 HRDLKAENLLLDADMNIKIADFGFSNEFTFGN-KLDTFCGSPPYAAPELFQGKKYDGPEV 198
Query: 874 DIWSLXXXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
D+WSL P+ L E LR Y I P +S L
Sbjct: 199 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI----------PFYMSTDCENLL 248
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
L+++P RGT +++D ++ + E+ L P V+
Sbjct: 249 KKFLILNPSKRGTLEQIMKDRWM-NVGHEDDELKPYVE 285
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 118 bits (295), Expect = 5e-26
Identities = 85/278 (30%), Positives = 135/278 (47%), Gaps = 23/278 (8%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
Y+ L IG+G V A + T VA+K ++ + L + E+ +MK H NI
Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNI 112
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V + L++VMEY GG + D +V H + E + A R+ + +Q+ H K ++
Sbjct: 113 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV 172
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL + +IK+ DFGF + N K T G+P + APE+ K+Y GP+V
Sbjct: 173 HRDLKAENLLLDADMNIKIADFGFSNEFTFGN-KLDTFCGSPPYAAPELFQGKKYDGPEV 231
Query: 874 DIWSLXXXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
D+WSL P+ L E LR Y I P +S L
Sbjct: 232 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI----------PFYMSTDCENLL 281
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
L+++P RGT +++D ++ + E+ L P V+
Sbjct: 282 KKFLILNPSKRGTLEQIMKDRWM-NVGHEDDELKPYVE 318
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 118 bits (295), Expect = 5e-26
Identities = 87/278 (31%), Positives = 137/278 (48%), Gaps = 23/278 (8%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
YK L IG+G V A + T VAIK ++ L + E+ +MK H NI
Sbjct: 122 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNI 181
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V L++V+EY GG + D +V H + E + A R+ + +Q+LHSK +I
Sbjct: 182 VKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNII 241
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL + +IK+ DFGF + N K T G+P + APE+ S K+Y GP+V
Sbjct: 242 HRDLKAENLLLDQDMNIKIADFGFSNTFSLGN-KLDTFCGSPPYAAPELFSGKKYDGPEV 300
Query: 874 DIWSLXXXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
D+WSL P+ L E LR Y I P +S L
Sbjct: 301 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI----------PFYMSTDCENLL 350
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
L+++P+ R + ++++D ++ + E+ L P ++
Sbjct: 351 KKFLVINPQRRSSLDNIMKDRWM-NVGYEDDELKPFIE 387
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 118 bits (295), Expect = 5e-26
Identities = 87/278 (31%), Positives = 137/278 (48%), Gaps = 23/278 (8%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
YK L IG+G V A + T VAIK ++ L + E+ +MK H NI
Sbjct: 170 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNI 229
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V L++V+EY GG + D +V H + E + A R+ + +Q+LHSK +I
Sbjct: 230 VKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNII 289
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL + +IK+ DFGF + N K T G+P + APE+ S K+Y GP+V
Sbjct: 290 HRDLKAENLLLDQDMNIKIADFGFSNTFSLGN-KLDTFCGSPPYAAPELFSGKKYDGPEV 348
Query: 874 DIWSLXXXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
D+WSL P+ L E LR Y I P +S L
Sbjct: 349 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI----------PFYMSTDCENLL 398
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
L+++P+ R + ++++D ++ + E+ L P ++
Sbjct: 399 KKFLVINPQRRSSLDNIMKDRWM-NVGYEDDELKPFIE 435
>At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 354
Score = 118 bits (295), Expect = 5e-26
Identities = 80/267 (29%), Positives = 138/267 (50%), Gaps = 11/267 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIK--QMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDS 761
IG+G+SG V T A+K Q+N E+ + I E+ + S+ +V+ S
Sbjct: 74 IGKGSSGNVQLVKHKLTQQFFALKVIQLNTEESTCRA-ISQELRINLSSQCPYLVSCYQS 132
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLH-SKGVIHRDIK 819
+ G + +++E+M+GGSL D++ + E + A+ + L+GL ++H + +IHRD+K
Sbjct: 133 FYHNGLVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHERRIIHRDLK 192
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
N+L++ G++K+TDFG + + + VGT +M+PE +S Y K DIWSL
Sbjct: 193 PSNLLINHRGEVKITDFGVSKILTSTSSLANSFVGTYPYMSPERISGSLYSNKSDIWSLG 252
Query: 880 XXXXXXXXXXPPYL---NETPLRALYLI--ATNGTPKLKDPGNL-SHKMAMFLNWCLMVD 933
PY ++ ++Y + A P P NL S + F++ C+ D
Sbjct: 253 LVLLECATGKFPYTPPEHKKGWSSVYELVDAIVENPPPCAPSNLFSPEFCSFISQCVQKD 312
Query: 934 PEDRGTAADLLEDPFITEIAEENTSLA 960
P DR +A +LLE F+ + +T+L+
Sbjct: 313 PRDRKSAKELLEHKFVKMFEDSDTNLS 339
>YLR362w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 717
Score = 117 bits (294), Expect = 7e-26
Identities = 83/302 (27%), Positives = 145/302 (47%), Gaps = 53/302 (17%)
Query: 699 KNLIK---IGQGASGGVYTAYELGTNASVAIKQMNL-----------------------E 732
KN +K IG G+ G VY T +A+KQ+ + E
Sbjct: 413 KNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQE 472
Query: 733 KQPKK---------------------ELIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVV 771
+Q +K + + +E+ ++K H NIV + + G+L +
Sbjct: 473 EQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIF 532
Query: 772 MEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGD 830
+EY+ GGS++ ++ + E I +R+ L G+ +LH K +IHRDIK NIL+ + G
Sbjct: 533 LEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC 592
Query: 831 IKLTDFGFCAQINEVNL---KRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXXXXXXX 887
+K+TDFG +++ +N KR ++ G+ +WM+PEVV + K DIWS
Sbjct: 593 VKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT 652
Query: 888 XXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDP 947
P+ + + ++A++ I TN TP++ P + + FL +D + R +A +LL+ P
Sbjct: 653 GKHPFPDFSQMQAIFKIGTNTTPEI--PSWATSEGKNFLRKAFELDYQYRPSALELLQHP 710
Query: 948 FI 949
++
Sbjct: 711 WL 712
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 117 bits (294), Expect = 7e-26
Identities = 73/253 (28%), Positives = 127/253 (49%), Gaps = 9/253 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIK---QMNLEKQPKKELIVNEILVMKGSKHNNIVNFID 760
+G+G Y A + T ++ A+K Q + K ++E I+NEI + + +H +IV F
Sbjct: 29 LGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSH 88
Query: 761 SYLFRGDLWVVMEYMEGGSLTDV--VTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ ++++ +E SL + H +L E ++ R+ L GL++LH +G++HRD+
Sbjct: 89 HFEDADNIYIFLELCSRKSLAHIWKARHTLL-EPEVRYYLRQILSGLKYLHQRGILHRDL 147
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
K N ++ N ++K+ DFG A++ ++ T+ GTP ++APEV+ R+ +GP+ D+WSL
Sbjct: 148 KLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSL 207
Query: 879 XXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRG 938
PP+ L+ Y L P +LS L L P DR
Sbjct: 208 GCVMYTLLCGSPPF-ETADLKETYRCIKQVHYTL--PASLSLPARQLLAAILRASPRDRP 264
Query: 939 TAADLLEDPFITE 951
+ +L F T+
Sbjct: 265 SIDQILRHDFFTK 277
>Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 438
Score = 117 bits (294), Expect = 7e-26
Identities = 76/260 (29%), Positives = 132/260 (50%), Gaps = 10/260 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPK-KELIVNEILVMKGSKHNNIVNFIDSY 762
+G G G VY AY + + +A+K + L+ + ++ I++E+ ++ + I+ F ++
Sbjct: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAF 231
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDN 822
+ + E+M+GGSL DV + E +G ++ +KGL +L S ++HRD+K N
Sbjct: 232 FVENRISICTEFMDGGSL-DVYRK--MPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSN 288
Query: 823 ILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXX 882
+L++ G +KL DFG Q+ VN T VGT +MAPE +S ++YG D+WSL
Sbjct: 289 MLVNTRGQVKLCDFGVSTQL--VNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISF 346
Query: 883 XXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAAD 942
+ PL+ L I +P L G S F+ C+ P++R +
Sbjct: 347 MEIQKNQGSLM---PLQLLQCIVDEDSPVL-PVGEFSEPFVHFITQCMRKQPKERPAPEE 402
Query: 943 LLEDPFITEIAEENTSLAPL 962
L+ PFI + + N ++ +
Sbjct: 403 LMGHPFIVQFNDGNAAVVSM 422
>Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 467
Score = 117 bits (294), Expect = 7e-26
Identities = 76/260 (29%), Positives = 132/260 (50%), Gaps = 10/260 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPK-KELIVNEILVMKGSKHNNIVNFIDSY 762
+G G G VY AY + + +A+K + L+ + ++ I++E+ ++ + I+ F ++
Sbjct: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAF 231
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDN 822
+ + E+M+GGSL DV + E +G ++ +KGL +L S ++HRD+K N
Sbjct: 232 FVENRISICTEFMDGGSL-DVYRK--MPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSN 288
Query: 823 ILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXX 882
+L++ G +KL DFG Q+ VN T VGT +MAPE +S ++YG D+WSL
Sbjct: 289 MLVNTRGQVKLCDFGVSTQL--VNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISF 346
Query: 883 XXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAAD 942
+ PL+ L I +P L G S F+ C+ P++R +
Sbjct: 347 MEIQKNQGSLM---PLQLLQCIVDEDSPVL-PVGEFSEPFVHFITQCMRKQPKERPAPEE 402
Query: 943 LLEDPFITEIAEENTSLAPL 962
L+ PFI + + N ++ +
Sbjct: 403 LMGHPFIVQFNDGNAAVVSM 422
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 117 bits (294), Expect = 7e-26
Identities = 79/252 (31%), Positives = 130/252 (51%), Gaps = 11/252 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMN---LEKQPKKELIVNEILVMKGSKHNNIVNFID 760
+G+G G VY E+ T SVAIK +N ++++ E I EI +M+ +H NIV +
Sbjct: 21 LGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVRHPNIVELKE 80
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ +MEY++GG L + L E ++ + + F HS+GV HRD+K
Sbjct: 81 VMATKTKIFFIMEYVKGGELFSKIVKGKLKEDSARKYFQQLISAVDFCHSRGVSHRDLKP 140
Query: 821 DNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+L+ NGD+K++DFG A QI + L T GTP ++APEV+ +K Y G K DIW
Sbjct: 141 ENLLVDENGDLKVSDFGLSALPEQILQDGLLH-TQCGTPAYVAPEVLRKKGYDGAKGDIW 199
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S P+ +E ++ I + + + P S + ++ L+VDP
Sbjct: 200 SCGIILYVLLAGFLPFQDENLMKMYRKIFKS---EFEYPPWFSPESKRLISKLLVVDPNK 256
Query: 937 RGTAADLLEDPF 948
R + ++ P+
Sbjct: 257 RISIPAIMRTPW 268
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 117 bits (293), Expect = 9e-26
Identities = 85/275 (30%), Positives = 131/275 (46%), Gaps = 23/275 (8%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
Y+ L IG+G S V A + T VAIK ++ + L + E+ +MKG H NI
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNI 118
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V + L++VMEY G + D +V+H + E + A R+ + + + H K ++
Sbjct: 119 VKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 178
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL +IK+ DFGF + + K T G+P + APE+ K+Y GP+V
Sbjct: 179 HRDLKAENLLLDAEANIKIADFGFSNEFT-LGSKLDTFCGSPPYAAPELFQGKKYDGPEV 237
Query: 874 DIWSLXXXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
DIWSL P+ L E LR Y + P +S L
Sbjct: 238 DIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRV----------PFYMSTDCESIL 287
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAP 961
L+++P R T +++D +I I E L P
Sbjct: 288 RRFLVLNPAKRCTLEQIMKDKWI-NIGYEGEELKP 321
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 116 bits (291), Expect = 2e-25
Identities = 75/253 (29%), Positives = 136/253 (53%), Gaps = 11/253 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN----EILVMKGSKHNNIVNFI 759
+G GA V+ A + T SVA+K +N +K + N EI +M+ H NIV
Sbjct: 27 LGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNIVKLH 86
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ + ++ ME+++GG L + ++ H L+E ++ + + + H++GV HRD+
Sbjct: 87 EVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHRDL 146
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRT--TMVGTPYWMAPEVVSRKEY-GPKVDI 875
K +N+L+ NG++K++DFG A +++ T+ GTP ++APE++S+K Y G KVD+
Sbjct: 147 KPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDV 206
Query: 876 WSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
WS P+ N+ + +Y G + + P +S + F++ L ++PE
Sbjct: 207 WSCGIVLFVLVAGYLPF-NDPNVMNMYKKIYKG--EYRFPRWMSPDLKRFVSRLLDINPE 263
Query: 936 DRGTAADLLEDPF 948
R T ++L+DP+
Sbjct: 264 TRITIDEILKDPW 276
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 116 bits (290), Expect = 2e-25
Identities = 83/249 (33%), Positives = 126/249 (50%), Gaps = 11/249 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN---EILVMKGSKHNNIVNFID 760
+G G VY A + SVAIK ++ EK K LI + EI +++ +H NIV +
Sbjct: 34 LGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHIKREISILRRVRHPNIVQLFE 93
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ VMEY++GG L + V L E ++ + + F H +GV HRD+K
Sbjct: 94 VMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCHFRGVYHRDLKP 153
Query: 821 DNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+LL NG++K++DFG A QI + L T GTP ++APEV++RK Y G KVDIW
Sbjct: 154 ENLLLDENGNLKVSDFGLSAVSDQIRQDGLFH-TFCGTPAYVAPEVLARKGYDGAKVDIW 212
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S P+ ++ + A+Y G + P ++ L L PE
Sbjct: 213 SCGVILFVLMAGFLPF-HDRNVMAMYKKIYRG--DFRCPRWFPVEINRLLIRMLETKPER 269
Query: 937 RGTAADLLE 945
R T D++E
Sbjct: 270 RFTMPDIME 278
>At2g32510 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 372
Score = 116 bits (290), Expect = 2e-25
Identities = 78/270 (28%), Positives = 135/270 (49%), Gaps = 19/270 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYL 763
+G+G++ VY A ++ +A+K + + E + E ++ ++ + S
Sbjct: 9 LGRGSTATVYAAAGHNSDEILAVKSSEVHRS---EFLQREAKILSSLSSPYVIGYRGSET 65
Query: 764 FRGDLWVVM-----EYMEGGSLTDVVTHC--ILTEGQIGAVSRETLKGLQFLHSKGVIHR 816
R VVM EY G+LTD + E ++ +R+ LKGL+++HSKG++H
Sbjct: 66 KRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVKYTRDILKGLEYIHSKGIVHC 125
Query: 817 DIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIW 876
D+K N+++S G+ K+ DFG +++ V + ++GTP +MAPEV ++ G + DIW
Sbjct: 126 DVKGSNVVISEKGEAKIADFGCAKRVDPV--FESPVMGTPAFMAPEVARGEKQGKESDIW 183
Query: 877 SLXXXXXXXXXXXPPYL----NETPLRALYLIA-TNGTPKLKDPGNLSHKMAMFLNWCLM 931
++ PP+ E P+ LY + ++ TP+L P L+ + FL CL
Sbjct: 184 AVGCTMIEMVTGSPPWTKADSREDPVSVLYRVGYSSETPEL--PCLLAEEAKDFLEKCLK 241
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAP 961
+ +R TA LL PF+T + L P
Sbjct: 242 REANERWTATQLLNHPFLTTKPDIEPVLVP 271
>YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 506
Score = 115 bits (289), Expect = 3e-25
Identities = 84/280 (30%), Positives = 133/280 (47%), Gaps = 22/280 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMN-LEKQPK-KELIVNEILVMKGSKHNNIVNFIDS 761
+G+GA G V A+K +N + P+ ++ I E+ K K + IV +
Sbjct: 220 LGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGM 279
Query: 762 YLFR--GDLWVVMEYMEGGSLTDVVTHCI-----LTEGQIGAVSRETLKGLQFLHSKGVI 814
+ +++ MEYM G SL + + ++E IG ++ L+GL +LH + VI
Sbjct: 280 FTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVI 339
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
HRDIK NILL+ G+IKL DFG + VN T GT ++MAPE + + Y D
Sbjct: 340 HRDIKPQNILLNEKGEIKLCDFGVSGE--AVNSLAMTFTGTSFYMAPERIQGQPYSVTCD 397
Query: 875 IWSLXXXXXXXXXXXPPY------LNETPLRALYLIATNGTPKLKDPGNL----SHKMAM 924
+WSL P+ N P+ L +I T +P+LKD L S
Sbjct: 398 VWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILT-FSPQLKDEPELDISWSKTFRS 456
Query: 925 FLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
F+++CL D +R + +L+ P+I ++ ++ VK
Sbjct: 457 FIDYCLKKDARERPSPRQMLKHPWIVGQMKKKVNMERFVK 496
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 115 bits (289), Expect = 3e-25
Identities = 86/273 (31%), Positives = 137/273 (49%), Gaps = 18/273 (6%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK---ELIVNEILVMKG-SKHNNIVNF 758
++G+G G + E+ T A K+++ EK + E + E+ +M+ KH NIV+F
Sbjct: 71 ELGRGEFGVTHECIEISTRERFACKRISKEKLRTEIDVEDVRREVEIMRCLPKHPNIVSF 130
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
+++ + +++VME EGG L D +V+ TE +V++ L+ ++ H GVIHRD
Sbjct: 131 KEAFEDKDAVYLVMEICEGGELFDRIVSRGHYTERAAASVAKTILEVVKVCHEHGVIHRD 190
Query: 818 IKSDNILLSMNG----DIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKV 873
+K +N L S NG +K DFG + +VG+PY+MAPEV+ R+ YGP++
Sbjct: 191 LKPENFLFS-NGTETAQLKAIDFGLSIFFKPAQ-RFNEIVGSPYYMAPEVL-RRNYGPEI 247
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMAMFLNWCLMV 932
D+WS PP+ ET + I +DP +SH+ + L
Sbjct: 248 DVWSAGVILYILLCGVPPFWAETEEGIAHAIVRGNIDFERDPWPKVSHEAKELVKNMLDA 307
Query: 933 DPEDRGTAADLLEDPFITEIAEENTSLAPLVKL 965
+P R T ++LE P+I N AP V L
Sbjct: 308 NPYSRLTVQEVLEHPWI-----RNAERAPNVNL 335
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 115 bits (288), Expect = 3e-25
Identities = 86/278 (30%), Positives = 136/278 (47%), Gaps = 23/278 (8%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
Y+ L IG+G V A + T VAIK ++ + L + E+ +MK H NI
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V + + L+++MEY GG + D +V H + E + + R+ + +Q+ H K ++
Sbjct: 116 VKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL + +IK+ DFGF + V K T G+P + APE+ K+Y GP+V
Sbjct: 176 HRDLKAENLLLDADMNIKIADFGFSNEFT-VGGKLDTFCGSPPYAAPELFQGKKYDGPEV 234
Query: 874 DIWSLXXXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
D+WSL P+ L E LR Y I P +S L
Sbjct: 235 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI----------PFYMSTDCENLL 284
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
L+++P RGT +++D +I EE+ L P V+
Sbjct: 285 KRFLVLNPIKRGTLEQIMKDRWINAGHEED-ELKPFVE 321
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 115 bits (288), Expect = 3e-25
Identities = 79/276 (28%), Positives = 137/276 (49%), Gaps = 8/276 (2%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IVNEILVMKGSKHNNIVNFID 760
+G G+ V A + T VAIK +N K + + EI +++ H +I+ +
Sbjct: 25 LGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYE 84
Query: 761 SYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
D++VVMEY++ G L D +V L E + + ++ + G+++ H ++HRD+K
Sbjct: 85 VIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLK 144
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
+N+LL +IK+ DFG +++ + +T+ G+P + APEV+S K YGP VDIWS
Sbjct: 145 PENVLLDSQCNIKIVDFGLSNVMHDGHFLKTS-CGSPNYAAPEVISGKPYGPDVDIWSCG 203
Query: 880 XXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGT 939
P+ +E + ++ G L P +LSH + LMVDP R +
Sbjct: 204 VILYALLCGTLPFDDEN-IPNVFEKIKRGMYTL--PNHLSHFARDLIPRMLMVDPTMRIS 260
Query: 940 AADLLEDPFITEIAEENTSLAPLVKLARMKKLAESM 975
++ + P+ S+ PL + + KK+ E +
Sbjct: 261 ITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEI 296
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 115 bits (288), Expect = 3e-25
Identities = 75/248 (30%), Positives = 128/248 (51%), Gaps = 9/248 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IVNEILVMKGSKHNNIVNFID 760
+G G+ VY A + + VAIK ++ EK K L I EI +++ +H IV+ ++
Sbjct: 63 LGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVRHPYIVHLLE 122
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ +++VMEY+ GG L + V L EG ++ + + F HS+GV HRD+K
Sbjct: 123 VMATKTKIYIVMEYVRGGELYNTVARGRLREGTARRYFQQLISSVAFCHSRGVYHRDLKL 182
Query: 821 DNILLSMNGDIKLTDFGFCAQINEVNLKR--TTMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
+N+LL G++K++DFG ++ + T GTP ++APEV++RK Y G K DIWS
Sbjct: 183 ENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEGAKADIWS 242
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
P+ ++ + +Y G + K P S ++A + L +P+ R
Sbjct: 243 CGVILFVLMAGYLPF-DDKNILVMYTKIYKG--QFKCPKWFSPELARLVTRMLDTNPDTR 299
Query: 938 GTAADLLE 945
T ++++
Sbjct: 300 ITIPEIMK 307
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 114 bits (286), Expect = 6e-25
Identities = 81/262 (30%), Positives = 124/262 (46%), Gaps = 17/262 (6%)
Query: 704 IGQGASGGVYTA-YELGTNASVAIKQMNLEKQPKKELIVN-EILVMKGSKHNNIVNFIDS 761
+G GA V+ + T+ VAIK +N + K ++++ EI ++K +H NIV D
Sbjct: 15 VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDV 74
Query: 762 YLFRGDLWVVMEYMEGGSLTDVV-THCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+++VMEY GG L D + L+E I + ++ LHSKG+IHRD+K
Sbjct: 75 QELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKP 134
Query: 821 DNILLSMNGD---------IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
NILLS IK+ DFGF ++ N+ T+ G+P +MAPEV+ + Y
Sbjct: 135 QNILLSYANRRKSSVSGIRIKIADFGFARYLHS-NMMAATLCGSPMYMAPEVIMSQHYDA 193
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETP--LRALYLIATNGTPKLKDPGNLSHKMAMFLNWC 929
K D+WS+ PP+ +P LR Y + P + P S +A L
Sbjct: 194 KADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSI--PRETSPYLANLLLGL 251
Query: 930 LMVDPEDRGTAADLLEDPFITE 951
L + +DR PF+ +
Sbjct: 252 LQRNQKDRMDFEAFFSHPFLEQ 273
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 114 bits (286), Expect = 6e-25
Identities = 80/256 (31%), Positives = 128/256 (49%), Gaps = 13/256 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQP---KKELIVNEILVMKGSKHNNIVNFID 760
+G GA V+ A E ++A ++K+ K+E + NEI V++ +HNNIV D
Sbjct: 28 LGTGAFSKVFLA-ESKSDAGQMYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQLFD 86
Query: 761 SYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+Y + +++VME + GG L D +V TE + R+ L+ + F+H GV+HRD+K
Sbjct: 87 TYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHDNGVVHRDLK 146
Query: 820 SDNILL---SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIW 876
+N+L + I ++DFG E + T GTP ++APEV+ +K YG VD+W
Sbjct: 147 PENLLYYNQDEDSKIMISDFGLSK--TEDSGVMATACGTPGYVAPEVLQQKPYGKAVDVW 204
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAMFLNWCLMVDP 934
S+ PP+ +E+ L+ G + P +S F+ + DP
Sbjct: 205 SIGVIAYILLCGYPPFYDESDAN-LFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDP 263
Query: 935 EDRGTAADLLEDPFIT 950
E R T D L P+I+
Sbjct: 264 EARFTCQDALSHPWIS 279
>YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 508
Score = 114 bits (285), Expect = 7e-25
Identities = 84/280 (30%), Positives = 134/280 (47%), Gaps = 22/280 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMN-LEKQPK-KELIVNEILVMKGSKHNNIVNFIDS 761
+G+GA G V + A+K +N L P+ ++ I E+ + + IV +
Sbjct: 227 LGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGM 286
Query: 762 YLF--RGDLWVVMEYMEGGSLTDVVTHCI-----LTEGQIGAVSRETLKGLQFLHSKGVI 814
+ +++ MEYM G SL + + + ++E +G ++ L+GL +LH K VI
Sbjct: 287 FTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVI 346
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
HRDIK NILL+ NG +KL DFG + VN TT GT ++MAPE + + Y D
Sbjct: 347 HRDIKPQNILLNENGQVKLCDFGVSGE--AVNSLATTFTGTSFYMAPERIQGQPYSVTSD 404
Query: 875 IWSLXXXXXXXXXXXPPYLNE------TPLRALYLIATNGTPKLKD--PGNL--SHKMAM 924
+WSL P +E P L I T TP+LKD N+ S
Sbjct: 405 VWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILT-FTPELKDEPESNIIWSPSFKS 463
Query: 925 FLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
F+++CL D +R + ++ P+I ++N ++ V+
Sbjct: 464 FIDYCLKKDSRERPSPRQMINHPWIKGQMKKNVNMEKFVR 503
>Hs4758702 [T] KOG4279 Serine/threonine protein kinase
Length = 1011
Score = 114 bits (285), Expect = 7e-25
Identities = 79/256 (30%), Positives = 128/256 (49%), Gaps = 13/256 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYL 763
+G+G G VY + T +AIK++ + + EI + + +H NIV ++ S
Sbjct: 377 LGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSAS 436
Query: 764 FRGDLWVVMEYMEGGSLTDVVTH----CILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
G L + ME + GGSL+ ++ E I +R+ L+GL +LH ++HRDIK
Sbjct: 437 QGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIK 496
Query: 820 SDNILL-SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR--KEYGPKVDIW 876
DN+L+ + +G +K++DFG ++ + T GT +MAPE++ + + YG DIW
Sbjct: 497 GDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIW 556
Query: 877 SLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKD--PGNLSHKMAMFLNWCLMVD 933
SL PP+ +P A++ + G K+ P +LS + FL D
Sbjct: 557 SLGCTVIEMATGRPPFHELGSPQAAMFQV---GMYKVHPPMPSSLSAEAQAFLLRTFEPD 613
Query: 934 PEDRGTAADLLEDPFI 949
P R +A LL DPF+
Sbjct: 614 PRLRASAQTLLGDPFL 629
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 114 bits (285), Expect = 7e-25
Identities = 87/251 (34%), Positives = 127/251 (49%), Gaps = 15/251 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IVNEILVMKGSKHNNIVNFID 760
+GQG VY TN SVAIK ++ +K + L I EI VM+ +KH N+V +
Sbjct: 18 LGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKREISVMRIAKHPNVVELYE 77
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ V+EY +GG L + V L E + + + F HS+GV HRDIK
Sbjct: 78 VMATKSRIYFVIEYCKGGELFNKVAKGKLKEDVAWKYFYQLISAVDFCHSRGVYHRDIKP 137
Query: 821 DNILLSMNGDIKLTDFGFCAQIN---EVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+LL N ++K++DFG A + + L TT GTP ++APEV++RK Y G K DIW
Sbjct: 138 ENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTT-CGTPAYVAPEVINRKGYEGTKADIW 196
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDP-- 934
S P+ ++T L +Y G K P + ++ L C M+DP
Sbjct: 197 SCGVVLFVLLAGYLPF-HDTNLMEMY--RKIGKADFKCPSWFAPEVKRLL--CKMLDPNH 251
Query: 935 EDRGTAADLLE 945
E R T A + E
Sbjct: 252 ETRITIAKIKE 262
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 114 bits (284), Expect = 1e-24
Identities = 84/289 (29%), Positives = 140/289 (48%), Gaps = 32/289 (11%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQ-MNLEKQPK-KELIVNEILVMKGSKHNNI 755
Y+ + KIG+G+ G V+ T VAIK+ + E P K++ + EI ++K KH N+
Sbjct: 5 YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNL 64
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKGVI 814
VN ++ + + L +V EY + L ++ + + E + +++ +TL+ + F H I
Sbjct: 65 VNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCI 124
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPE-VVSRKEYGPKV 873
HRD+K +NIL++ + IKL DFGF + + T V T ++ +PE +V +YGP V
Sbjct: 125 HRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV 184
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLI---------------ATN---GTPKLKDP 915
D+W++ P + ++ + LYLI +TN K+ DP
Sbjct: 185 DVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDP 244
Query: 916 ----------GNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAE 954
N+S+ L CL +DP +R T LL P+ I E
Sbjct: 245 EDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFENIRE 293
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 113 bits (283), Expect = 1e-24
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 8/254 (3%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK--QPKKELIVNEILVMKGSKHNNI 755
Y+ + +G+GA G ++ V IK++N+ ++ L +NE+ ++ +H NI
Sbjct: 171 YERIRTVGKGAFGSAVLYRRREDSSLVIIKEINMYDLDSSQRRLALNEVSLLSRIEHPNI 230
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVV--THCILTEGQIGAVSRETLKGLQFLHSKGV 813
+ + DS+ G L + MEY +GG+L ++ T +L E QIG + + + +LH V
Sbjct: 231 IAYYDSFEEEGVLMIEMEYADGGTLAQMLSRTQNLLDEEQIGDMMIQMCSAVAYLHENSV 290
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKR--TTMVGTPYWMAPEVVSRKEYGP 871
+HRD+K+ N+ L+ + +K+ DFG + L + T+VGTPY+++PE+ S Y
Sbjct: 291 LHRDLKTANVFLTRDSFVKIGDFGISKIMGTETLAQGAKTVVGTPYYISPEMCSGVSYNE 350
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
K D+W+L + + + I T +K P S +M M + L
Sbjct: 351 KSDMWALGCILYEMCCLKKAFEGDNLPALVNSIMTCAYTPVKGP--YSAEMKMVIRELLQ 408
Query: 932 VDPEDRGTAADLLE 945
+DP+ R +A L+
Sbjct: 409 LDPQKRPSAPQALK 422
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 112 bits (281), Expect = 2e-24
Identities = 77/271 (28%), Positives = 135/271 (49%), Gaps = 12/271 (4%)
Query: 696 KLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNN 754
K Y+ IG G V T + A+K ++ + + K++++ +EIL+++ H N
Sbjct: 282 KHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPN 341
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKGV 813
IV + Y ++++++EY++GG L D + + E + + K L +H K +
Sbjct: 342 IVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSI 401
Query: 814 IHRDIKSDNILLSMNGD----IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY 869
+HRD+K +N+L+ N D +KL DFG + T+ GTP ++APE++S K Y
Sbjct: 402 VHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIF---TVCGTPTYVAPEILSEKGY 458
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDP--GNLSHKMAMFL 926
G +VD+W+ PP+ + E L+ I G + P N+S +
Sbjct: 459 GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLV 518
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENT 957
+ L+VDP+ R TA +L+ P+I + NT
Sbjct: 519 SRLLVVDPKKRYTAHQVLQHPWIETAGKTNT 549
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 112 bits (281), Expect = 2e-24
Identities = 79/249 (31%), Positives = 126/249 (49%), Gaps = 9/249 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELI---VNEILVMKGSKHNNIVNFID 760
+GQG VY A + T SVAIK ++ +K K LI EI VM+ +H ++V +
Sbjct: 18 LGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPHVVFLHE 77
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ MEY++GG L D V+ L E ++ + + + HS+GV HRD+K
Sbjct: 78 VMASKTKIYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHSRGVYHRDLKP 137
Query: 821 DNILLSMNGDIKLTDFGFCA--QINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
+N+LL NGD+K++DFG A + + + T GTP ++APEV+ +K Y G K D+WS
Sbjct: 138 ENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDGAKADVWS 197
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
P+ +E L +Y T G + K P ++ L+ L +P R
Sbjct: 198 CGVVLYVLLAGFLPF-HEQNLVEMYRKITKG--EFKCPNWFPPEVKKLLSRILDPNPNSR 254
Query: 938 GTAADLLED 946
++E+
Sbjct: 255 IKIEKIMEN 263
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 112 bits (280), Expect = 3e-24
Identities = 77/283 (27%), Positives = 135/283 (47%), Gaps = 8/283 (2%)
Query: 687 EICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPK--KELIVNEI 744
+I T Y+ + +IG+GA G + +K++ L KQ + K + E+
Sbjct: 4 KISETASKMDDYEVVEQIGRGAFGSAFLVIHKSERRKYVVKKIRLAKQTERCKLAAIQEM 63
Query: 745 LVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRET 801
++ K IV + DS++ + + +V Y EGG +T ++ +E ++ +
Sbjct: 64 SLISKLKSPYIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQL 123
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
L + +LH+ V+HRD+K NI L+ +++L DFG + + +L ++MVGTP +M P
Sbjct: 124 LLAIDYLHNNRVLHRDLKCSNIFLTKENEVRLGDFGLAKLLGKDDL-ASSMVGTPNYMCP 182
Query: 862 EVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHK 921
E+++ YG K DIWSL P + + P A + N + P S
Sbjct: 183 ELLADIPYGYKSDIWSLGCCMFEVAAHQPAF--KAPDMAALINKINRSSLSPLPVMYSSS 240
Query: 922 MAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVK 964
+ + L +PE R TAA+LL P + + +L+P+ K
Sbjct: 241 LKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQNLSPVFK 283
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 112 bits (279), Expect = 4e-24
Identities = 82/260 (31%), Positives = 127/260 (48%), Gaps = 15/260 (5%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGS-----KHNNIVN 757
K+G+G+ V + T VAIK ++ +K+ KK+ V + L +G +H NI
Sbjct: 67 KLGEGSFAKVREGLHVLTGEKVAIKVID-KKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125
Query: 758 FIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHR 816
+D ++VME GG+L + L E + R+ + ++ LH GV+HR
Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHR 185
Query: 817 DIKSDNILLSMNGDIKLTDFGF--CAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
D+K +N+LL + +IKL DFG CA I + +T G+P + APE+++RK+YGPK+D
Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKID 245
Query: 875 IWSLXXXXXXXXXXXPPYLNET-PLRALY--LIATNGTPKLKDPGNLSHKMAMFLNWCLM 931
+WS+ P+ E LRALY ++ P P LS FL L
Sbjct: 246 VWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPL---PTQLSTGAISFLRSLLE 302
Query: 932 VDPEDRGTAADLLEDPFITE 951
DP R L + ++ E
Sbjct: 303 PDPVKRPNIQQALANRWLNE 322
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 112 bits (279), Expect = 4e-24
Identities = 78/281 (27%), Positives = 136/281 (47%), Gaps = 8/281 (2%)
Query: 698 YKNLIKIGQGASGGVYTAYELGT-NASVAIKQMNLEKQPKK--ELIVNEILVMKGSKHNN 754
+K + IG+GA G V+ A +L VA+K++N+ PK+ E I E + K KH N
Sbjct: 6 FKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPKEFLEQIQQEYYIQKNMKHKN 65
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGV 813
IV + ++ E++ GG L + + + Q+ ++ + GL+++H G+
Sbjct: 66 IVKMYGMSMDTEFCYLFQEFVTGGDLFEKIDFENGMPVNQVKGYLKQLMSGLKYIHGCGI 125
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQ--INEVNLKRTTMVGTPYWMAPEVVSRKEY-G 870
+HRDIK DN+L++ + +K+ DFG + +++ + +GT +MAPE+ ++K++ G
Sbjct: 126 VHRDIKPDNLLINSSDALKIADFGLSTRFIVDDKEILLHERIGTTPFMAPELFAKKKHRG 185
Query: 871 PKVDIWSLXXXXXXXXXXXPPYLNETPLRALY-LIATNGTPKLKDPGNLSHKMAMFLNWC 929
P VDIWS P+ LY N T K LS + FL
Sbjct: 186 PPVDIWSAGILVFSLLTGNLPWDEPKESDILYSQWMNNKTSKNCIWYGLSTPVVRFLKKL 245
Query: 930 LMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKK 970
L + +R T ++ DP++ ++ EE + R K+
Sbjct: 246 LKENVNERATIEEIESDPWLEDLEEERENCTKFPTSTRRKR 286
>Hs20550407 [T] KOG0201 Serine/threonine protein kinase
Length = 112
Score = 111 bits (278), Expect = 5e-24
Identities = 53/107 (49%), Positives = 71/107 (65%)
Query: 772 MEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDI 831
MEY +GGS D++ L E QI + RE LKGL +LHS+ IHR +K+ N+LLS + ++
Sbjct: 1 MEYPDGGSTLDLLEPGPLDETQIITILREILKGLDYLHSEKKIHRGVKAANVLLSEHCEV 60
Query: 832 KLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
KL DFG Q+ + KR T VGTP+W+APEV+ + Y K DIWSL
Sbjct: 61 KLVDFGMAGQLADTQTKRNTFVGTPFWIAPEVIKQSAYDSKADIWSL 107
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 111 bits (278), Expect = 5e-24
Identities = 84/249 (33%), Positives = 125/249 (49%), Gaps = 11/249 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK---ELIVNEILVMKGSKHNNIVNFID 760
+GQG VY + TN SVAIK ++ EK K E I EI VM+ ++H N+V +
Sbjct: 18 LGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQIKREISVMRIARHPNVVELYE 77
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ VMEY +GG L + V L + + + + F HS+ V HRDIK
Sbjct: 78 VMATKTRIYFVMEYCKGGELFNKVAKGKLRDDVAWKYFYQLINAVDFCHSREVYHRDIKP 137
Query: 821 DNILLSMNGDIKLTDFGFCAQIN---EVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+LL N ++K++DFG A + + L TT GTP ++APEV++RK Y G K DIW
Sbjct: 138 ENLLLDDNENLKVSDFGLSALADCKRQDGLLHTT-CGTPAYVAPEVINRKGYDGTKADIW 196
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S P+ +++ L +Y G K P + ++ L L +PE
Sbjct: 197 SCGVVLFVLLAGYLPF-HDSNLMEMY--RKIGKADFKAPSWFAPEVRRLLCKMLDPNPET 253
Query: 937 RGTAADLLE 945
R T A + E
Sbjct: 254 RITIARIRE 262
>7301213 [R] KOG0589 Serine/threonine protein kinase
Length = 841
Score = 111 bits (278), Expect = 5e-24
Identities = 61/199 (30%), Positives = 105/199 (52%), Gaps = 7/199 (3%)
Query: 686 TEICTTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK--QPKKELIVNE 743
T + G Y+ + +GQG+ G + KQ+NL + P ++L +NE
Sbjct: 93 TGVGVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNE 152
Query: 744 ILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTH----CILTEGQIGAVSR 799
+ V H NIV+++ S++ L + MEY +GG+L ++ E I AV
Sbjct: 153 VDVFSKLHHPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFE 212
Query: 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWM 859
+ + ++HS+ ++HRD+K+ N+ L+ G +K+ DFG ++I + T++GTPY+
Sbjct: 213 QISSAINYMHSENILHRDLKTANVFLNRRGIVKIGDFGI-SKIMNTKIHAQTVLGTPYYF 271
Query: 860 APEVVSRKEYGPKVDIWSL 878
+PE+ KEY K DIW+L
Sbjct: 272 SPEMCEGKEYDNKSDIWAL 290
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 111 bits (277), Expect = 6e-24
Identities = 65/205 (31%), Positives = 107/205 (51%), Gaps = 7/205 (3%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK--ELIVNEILVMKGSKHNNIVNFID 760
+IG G+ V+ A VAIK++ +++ KK E +++EI +++ H NI+ ID
Sbjct: 17 QIGSGSFSVVWEARHRVDGTEVAIKEIAMDRLNKKLQESLMSEIFILRRINHPNIIRLID 76
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVV-THCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
G + +V+EY +GG L+ V H I+ E ++ GLQ L +IHRD+K
Sbjct: 77 MIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKHFMQQLAAGLQVLRDNNIIHRDLK 136
Query: 820 SDNILLSMN---GDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIW 876
N+LLS N D+K+ DFGF + L T+ G+P +MAPE++ ++Y K D+W
Sbjct: 137 PQNLLLSTNENDADLKIADFGFARSLQPRGLAE-TLCGSPLYMAPEIMQLQKYDAKADLW 195
Query: 877 SLXXXXXXXXXXXPPYLNETPLRAL 901
S+ P+ + ++ L
Sbjct: 196 SVGAILFQLVTGRTPFTGNSQIQLL 220
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 110 bits (275), Expect = 1e-23
Identities = 66/252 (26%), Positives = 127/252 (50%), Gaps = 8/252 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIV---NEILVMKGSKHNNIVNFID 760
+G+G+ GVY A + T VAIK ++ + K ++ NE+ + KH +I+ +
Sbjct: 18 LGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPSILELYN 77
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ +++V+E G + + + + +E + + + G+ +LHS G++HRD+
Sbjct: 78 YFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDL 137
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
N+LL+ N +IK+ DFG Q+ + K T+ GTP +++PE+ +R +G + D+WSL
Sbjct: 138 TLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSL 197
Query: 879 XXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRG 938
PP+ +T L + + P LS + ++ L +P DR
Sbjct: 198 GCMFYTLLIGRPPFDTDTVKNTLNKVV---LADYEMPTFLSIEAKDLIHQLLRRNPADRL 254
Query: 939 TAADLLEDPFIT 950
+ + +L+ PF++
Sbjct: 255 SLSSVLDHPFMS 266
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 110 bits (274), Expect = 1e-23
Identities = 80/286 (27%), Positives = 144/286 (49%), Gaps = 15/286 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK-----QPKKELIVNEILVMKGSKHNNIVNF 758
+G G+ G V A +L TN VAIK + L+K + +++ E+ +++ H NIV+F
Sbjct: 53 LGAGSFGVVRQARKLSTNEDVAIKIL-LKKALQGNNVQLQMLYEELSILQKLSHPNIVSF 111
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
D + + ++V + GG L D +++ TE + + L ++++HSK V+HRD
Sbjct: 112 KDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRD 171
Query: 818 IKSDNILL---SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
+K +N+L S N + + DFG Q+ G+ ++APEV+++ +G D
Sbjct: 172 LKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCD 231
Query: 875 IWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTP---KLKDPGNLSHKMAMFLNWCLM 931
IWS+ P++ E+ + + P + N+S + F+ L
Sbjct: 232 IWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALR 291
Query: 932 VDPEDRGTAADLLEDPFITEIAEENTSLAPLVK--LARMKKLAESM 975
++P DR TA +LL+DP+IT E +++ P VK + KKL +++
Sbjct: 292 LNPADRPTATELLDDPWITSKRVETSNILPDVKKGFSLRKKLRDAI 337
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 110 bits (274), Expect = 1e-23
Identities = 75/226 (33%), Positives = 116/226 (51%), Gaps = 9/226 (3%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLE---KQPKKELIVNEILVMKGSKHNN 754
++ L IG+GA G V+ TN A+K +N + K+ E +M +
Sbjct: 68 FRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSEW 127
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
IV ++ L++VMEYM GG L +++T ++E + E ++ L LHS G I
Sbjct: 128 IVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSYEVSEKWTRFYTAEIVEALAALHSMGYI 187
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKR-TTMVGTPYWMAPEVVSRK----EY 869
HRD+K DN+L+S++G IKL DFG C ++N + R +T VGTP +++PEV+ + E+
Sbjct: 188 HRDVKPDNMLISISGHIKLADFGTCVKMNANGVVRCSTAVGTPDYISPEVLRNQGQDAEF 247
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP 915
G +VD WS+ P+ E L + Y N LK P
Sbjct: 248 GKEVDWWSVGVFIYEMLVGETPFYAEA-LVSTYTNIMNHKTSLKFP 292
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 110 bits (274), Expect = 1e-23
Identities = 82/257 (31%), Positives = 122/257 (46%), Gaps = 11/257 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IVNEILVMKGSKHNNIVNFID 760
+G G VY A + T SVA+K + EK K + I EI VM+ KH NIV +
Sbjct: 30 LGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPNIVELHE 89
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ ME + GG L V L E ++ + + F HS+GV HRD+K
Sbjct: 90 VMASKSKIYFAMELVRGGELFAKVAKGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKP 149
Query: 821 DNILLSMNGDIKLTDFG---FCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+LL G++K+TDFG F + + L TT GTP ++APEV+ +K Y G K D+W
Sbjct: 150 ENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTT-CGTPAYVAPEVILKKGYDGAKADLW 208
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S P+ ++ L +Y G K PG LS + L +P
Sbjct: 209 SCGVILFVLLAGYLPFQDDN-LVNMYRKIYRG--DFKCPGWLSSDARRLVTKLLDPNPNT 265
Query: 937 RGTAADLLEDPFITEIA 953
R T +++ P+ + A
Sbjct: 266 RITIEKVMDSPWFKKQA 282
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 109 bits (273), Expect = 2e-23
Identities = 81/269 (30%), Positives = 129/269 (47%), Gaps = 23/269 (8%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFIDS 761
IG+G V A + T VA+K ++ + L + E+ +MK H NIV +
Sbjct: 66 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEV 125
Query: 762 YLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
L++VMEY GG + D +V H + E + A R+ + +Q+ H K ++HRD+K+
Sbjct: 126 IETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKA 185
Query: 821 DNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWSLX 879
+N+LL + +IK+ DFGF + V K T G+P + APE+ K+Y GP+VD+WSL
Sbjct: 186 ENLLLDGDMNIKIADFGFSNEFT-VGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 244
Query: 880 XXXXXXXXXXPPY-------LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMV 932
P+ L E LR Y I P +S L L++
Sbjct: 245 VILYTLVSGSLPFDGQNLKELRERVLRGKYRI----------PFYMSTDCENLLKKLLVL 294
Query: 933 DPEDRGTAADLLEDPFITEIAEENTSLAP 961
+P RG+ +++D ++ + E L P
Sbjct: 295 NPIKRGSLEQIMKDRWM-NVGHEEEELKP 322
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 109 bits (273), Expect = 2e-23
Identities = 78/254 (30%), Positives = 127/254 (49%), Gaps = 12/254 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK----ELIVNEILVMKGSKHNNIVNFI 759
+G+G VY E+ VAIK +N ++ K+ E I EI +MK +H NIV
Sbjct: 18 LGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHPNIVELK 77
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+ + ++ VME+++GG L ++ L E ++ + + + HS+GV HRD+K
Sbjct: 78 EVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAARRYFQQLISAVDYCHSRGVSHRDLK 137
Query: 820 SDNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDI 875
+N+LL NGD+K++DFG A QI + L T GTP ++APEV+ +K Y G K DI
Sbjct: 138 PENLLLDENGDLKISDFGLSALPEQILQDGLLH-TQCGTPAYVAPEVLKKKGYDGAKADI 196
Query: 876 WSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
WS P+ +E + I + P S + ++ L+VDP+
Sbjct: 197 WSCGVVLYVLLAGCLPFQDENLMNMYRKIF---RADFEFPPWFSPEARRLISKLLVVDPD 253
Query: 936 DRGTAADLLEDPFI 949
R + ++ P++
Sbjct: 254 RRISIPAIMRTPWL 267
>At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 546
Score = 109 bits (273), Expect = 2e-23
Identities = 80/266 (30%), Positives = 126/266 (47%), Gaps = 9/266 (3%)
Query: 687 EICTTG-DPSKLYKNLIKIGQGASGGVYTAYELGTNAS--VAIKQMNLEKQPKKEL--IV 741
EI T G D ++ +KI + + G Y GT S VAIK + ++ + L
Sbjct: 270 EIPTDGTDEWEIDVTQLKIEKKVASGSYGDLHRGTYCSQEVAIKFLKPDRVNNEMLREFS 329
Query: 742 NEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVV--THCILTEGQIGAVSR 799
E+ +M+ +H N+V F+ + L +V E+M GS+ D + C + V+
Sbjct: 330 QEVFIMRKVRHKNVVQFLGACTRSPTLCIVTEFMARGSIYDFLHKQKCAFKLQTLLKVAL 389
Query: 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWM 859
+ KG+ +LH +IHRD+K+ N+L+ +G +K+ DFG A++ + T GT WM
Sbjct: 390 DVAKGMSYLHQNNIIHRDLKTANLLMDEHGLVKVADFG-VARVQIESGVMTAETGTYRWM 448
Query: 860 APEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLS 919
APEV+ K Y K D++S PY TPL+A + G + K P
Sbjct: 449 APEVIEHKPYNHKADVFSYAIVLWELLTGDIPYAFLTPLQAAVGVVQKGL-RPKIPKKTH 507
Query: 920 HKMAMFLNWCLMVDPEDRGTAADLLE 945
K+ L C DPE R +++E
Sbjct: 508 PKVKGLLERCWHQDPEQRPLFEEIIE 533
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 109 bits (273), Expect = 2e-23
Identities = 85/284 (29%), Positives = 135/284 (46%), Gaps = 11/284 (3%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
YK + IG+G V A L T VAIK ++ + L + E+ +MK H NI
Sbjct: 151 YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 210
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVI 814
V L+++MEY GG + D +V H + E + R+ + +Q+ H K +I
Sbjct: 211 VKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRII 270
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKV 873
HRD+K++N+LL +IK+ DFGF + K T G+P + APE+ K+Y GP+V
Sbjct: 271 HRDLKAENLLLDSELNIKIADFGFSNEFTP-GSKLDTFCGSPPYAAPELFQGKKYDGPEV 329
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVD 933
D+WSL P+ T LR L G K + P +S L L+++
Sbjct: 330 DVWSLGVILYTLVSGSLPFDGST-LRELRERVLRG--KYRIPFYMSTDCENLLRKFLVLN 386
Query: 934 PEDRGTAADLLEDPFITEIAEEN---TSLAPLVKLARMKKLAES 974
P R + ++ D ++ EE+ + P LA K++ ++
Sbjct: 387 PAKRASLETIMGDKWMNMGFEEDELKPYIEPKADLADPKRIGKT 430
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 109 bits (273), Expect = 2e-23
Identities = 80/258 (31%), Positives = 129/258 (49%), Gaps = 13/258 (5%)
Query: 702 IKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFI 759
IKIGQG G VYTA T +A+K++ ++ + L + E+ +++G KH N+V +
Sbjct: 1327 IKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY 1386
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ R +L + ME G+L +V L E + + L G+ LH G++HRDI
Sbjct: 1387 GIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDI 1446
Query: 819 KSDNI-LLSMNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYWMAPEVVSRKE---YGP 871
K+ NI L+ + +KL DFG +I V + VGT +MAPEV ++ +G
Sbjct: 1447 KTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGR 1506
Query: 872 KVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCL 930
DIWS+ P+ ++ + ++ + P+ P +LS + F++ CL
Sbjct: 1507 AADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQA--PESLSQEGHDFIDHCL 1564
Query: 931 MVDPEDRGTAADLLEDPF 948
DP+ R TA +LLE F
Sbjct: 1565 QHDPKRRLTAVELLEHNF 1582
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 109 bits (272), Expect = 2e-23
Identities = 80/286 (27%), Positives = 134/286 (45%), Gaps = 31/286 (10%)
Query: 696 KLYKNLIKIGQGASGGVYTAYELGTNASVAIKQM-NLEKQPKKELIVNEILVMKGSKHNN 754
++Y+ L K+G+G+ G V T VAIK +Q ++ + EI +K H N
Sbjct: 2 EMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHEN 61
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKGV 813
+VN I+ + + + +V E+++ L ++ +C L ++ + L+ + +LHS +
Sbjct: 62 LVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNI 121
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR-KEYGPK 872
IHRDIK +NIL+S +G KL DFGF + T V T ++ APE+V + YG
Sbjct: 122 IHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKP 181
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALY---------------------LIATNGTPK 911
VDIW+L P + + L L+ + A P+
Sbjct: 182 VDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQ 241
Query: 912 LKDPGNLSHK-------MAMFLNWCLMVDPEDRGTAADLLEDPFIT 950
++ P N K +A ++ CL +DP DR +++DLL + T
Sbjct: 242 VQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFT 287
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 109 bits (272), Expect = 2e-23
Identities = 78/253 (30%), Positives = 124/253 (48%), Gaps = 9/253 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKE-LIVNEILVMKGSKHNNIVNFIDSY 762
+G GA V A + T VAIK + E KE + NEI V+ KH NIV D Y
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIY 85
Query: 763 LFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSD 821
G L+++M+ + GG L D +V TE + + L +++LH G++HRD+K +
Sbjct: 86 ESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPE 145
Query: 822 NIL---LSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
N+L L + I ++DFG +++ + +T GTP ++APEV+++K Y VD WS+
Sbjct: 146 NLLYYSLDEDSKIMISDFGL-SKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSI 204
Query: 879 XXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAMFLNWCLMVDPED 936
PP+ +E + L+ + P ++S F+ + DPE
Sbjct: 205 GVIAYILLCGYPPFYDENDAK-LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEK 263
Query: 937 RGTAADLLEDPFI 949
R T L+ P+I
Sbjct: 264 RFTCEQALQHPWI 276
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 109 bits (272), Expect = 2e-23
Identities = 74/262 (28%), Positives = 117/262 (44%), Gaps = 6/262 (2%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQ-PKKELIVNEILVMKGSKHNNIV 756
Y L IG+G+ G +N A+K++ L K + E +++ KH NIV
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNIV 63
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRETLKGLQFLHSKGV 813
F +S+ G L++VMEY +GG L + + E I + G+ +H K V
Sbjct: 64 AFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRV 123
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKV 873
+HRDIKS NI L+ NG +KL DFG ++ T VGTPY++ PE+ Y K
Sbjct: 124 LHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYNNKS 183
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVD 933
DIWSL P+ + + + L P + S+++ + +
Sbjct: 184 DIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPL--PSHYSYELQFLVKQMFKRN 241
Query: 934 PEDRGTAADLLEDPFITEIAEE 955
P R +A LL + + ++
Sbjct: 242 PSHRPSATTLLSRGIVARLVQK 263
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 109 bits (272), Expect = 2e-23
Identities = 75/261 (28%), Positives = 128/261 (48%), Gaps = 9/261 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IVNEILVMKGSKHNNIVNFID 760
+G GA VY T SVAIK ++ ++ K L I EI +M +H +IV +
Sbjct: 28 VGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQREIAIMHRLRHPSIVRLFE 87
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ VME+ +GG L V+ E ++ + + + HS+G+ HRD+K
Sbjct: 88 VLATKSKIFFVMEFAKGGELFAKVSKGRFCEDLSRRYFQQLISAVGYCHSRGIFHRDLKP 147
Query: 821 DNILLSMNGDIKLTDFGFCAQINEVNLKRT--TMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
+N+LL D+K++DFG A +++ T+ GTP ++APEV+++K Y G K+DIWS
Sbjct: 148 ENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDGAKIDIWS 207
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
P+ N+ L +Y G + + P S + L L +P+ R
Sbjct: 208 CGIILFVLNAGYLPF-NDHNLMVMYRKIYKG--EFRIPKWTSPDLRRLLTRLLDTNPQTR 264
Query: 938 GTAADLLEDPFITEIAEENTS 958
T +++ DP+ + ++ S
Sbjct: 265 ITIEEIIHDPWFKQGYDDRMS 285
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 109 bits (272), Expect = 2e-23
Identities = 82/259 (31%), Positives = 130/259 (49%), Gaps = 11/259 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPK---KELIVNEILVMKGSKHNNIVNFID 760
+GQG VY A L T SVAIK ++ E+ K E I EI M+ +H NIV +
Sbjct: 18 LGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPNIVELHE 77
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ VME+++GG L + V+ L E ++ ++ + F HS+GV HRD+K
Sbjct: 78 VMATKSKIYFVMEHVKGGELFNKVSTGKLREDVARKYFQQLVRAVDFCHSRGVCHRDLKP 137
Query: 821 DNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+LL +G++K++DFG A + L TT GTP ++APEV+SR Y G K D+W
Sbjct: 138 ENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTT-CGTPAYVAPEVISRNGYDGFKADVW 196
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S P+ ++ L LY G ++K P L+ L L +P
Sbjct: 197 SCGVILFVLLAGYLPF-RDSNLMELY--KKIGKAEVKFPNWLAPGAKRLLKRILDPNPNT 253
Query: 937 RGTAADLLEDPFITEIAEE 955
R + +++ + + +E
Sbjct: 254 RVSTEKIMKSSWFRKGLQE 272
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 109 bits (272), Expect = 2e-23
Identities = 79/249 (31%), Positives = 126/249 (49%), Gaps = 10/249 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIK---QMNLEKQPKKELIVNEILVMKGSKHNNIVNFID 760
IG+G V A T SVA+K + + K+ + I EI +MK +H +V +
Sbjct: 15 IGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCVVRLYE 74
Query: 761 SYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
R +++++EY+ GG L D +V + L+E + + + G+ + HSKGV HRD+K
Sbjct: 75 VLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVYHRDLK 134
Query: 820 SDNILLSMNGDIKLTDFGFCAQINE-VNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
+N+LL G++K++DFG A + V + +TT GTP ++APEV+S K Y G DIWS
Sbjct: 135 PENLLLDSQGNLKISDFGLSALPEQGVTILKTT-CGTPNYVAPEVLSHKGYNGAVADIWS 193
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
P+ +E L LY + + P + +N L +PE R
Sbjct: 194 CGVILYVLMAGYLPF-DEMDLPTLY--SKIDKAEFSCPSYFALGAKSLINRILDPNPETR 250
Query: 938 GTAADLLED 946
T A++ +D
Sbjct: 251 ITIAEIRKD 259
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 109 bits (272), Expect = 2e-23
Identities = 91/285 (31%), Positives = 137/285 (47%), Gaps = 12/285 (4%)
Query: 696 KLYKNLIK-IGQGASGGVYTAYELGTNASVAIKQMNLEK---QPKKELIVNEILVMKG-S 750
KL+ L K +G+G G Y E T A K ++ +K + K+ + EI +M+ S
Sbjct: 88 KLFYTLGKELGRGQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLS 147
Query: 751 KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLH 809
NIV F +Y + +VME GG L D ++ TE +V R+ + ++ H
Sbjct: 148 GQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRIIAKGHYTERAAASVCRQIVNVVKICH 207
Query: 810 SKGVIHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR 866
GV+HRD+K +N LLS + IK TDFG I E + R +VG+ Y++APEV+ R
Sbjct: 208 FMGVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGKVYR-DIVGSAYYVAPEVL-R 265
Query: 867 KEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMAMF 925
+ YG +VDIWS PP+ ET I P ++S
Sbjct: 266 RRYGKEVDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSAKDL 325
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKK 970
+ L DP+ R +AAD+L+ P++ E E + L+RMK+
Sbjct: 326 VRRMLTADPKRRISAADVLQHPWLREGGEASDKPIDSAVLSRMKQ 370
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 108 bits (271), Expect = 3e-23
Identities = 79/259 (30%), Positives = 120/259 (45%), Gaps = 15/259 (5%)
Query: 704 IGQGASGGVYTA-YELGTNASVAIKQMNLEKQPKKE-LIVNEILVMKGSKHNNIVNFIDS 761
IG GA V+ + + VA+K +N + K + L+ EI ++K KH NIV D
Sbjct: 22 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDF 81
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+++VMEY GG L D + H + L+E I ++ ++ LHSKG+IHRD+K
Sbjct: 82 QEMANSVYLVMEYCNGGDLADYL-HAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLK 140
Query: 820 SDNILLSMNGD---------IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYG 870
NILLS +K+ DFGF A+ + N+ T+ G+P +MAPEV+ + Y
Sbjct: 141 PQNILLSNPAGRRANPNSIRVKIADFGF-ARYLQSNMMAATLCGSPMYMAPEVIMSQHYD 199
Query: 871 PKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCL 930
K D+WS+ P+ +P N T P S + L L
Sbjct: 200 GKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALL 259
Query: 931 MVDPEDRGTAADLLEDPFI 949
+ +DR + PF+
Sbjct: 260 QRNHKDRMDFDEFFHHPFL 278
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 108 bits (271), Expect = 3e-23
Identities = 65/252 (25%), Positives = 127/252 (49%), Gaps = 8/252 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIV---NEILVMKGSKHNNIVNFID 760
+G+G+ GVY A + + VAIK ++ + K ++ NE+ + KH +I+ +
Sbjct: 18 LGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYN 77
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ +++V+E G + + + + +E + + + G+ +LHS G++HRD+
Sbjct: 78 YFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDL 137
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
N+LL+ N +IK+ DFG Q+ + K T+ GTP +++PE+ +R +G + D+WSL
Sbjct: 138 TLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSL 197
Query: 879 XXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRG 938
PP+ +T L + + P LS + ++ L +P DR
Sbjct: 198 GCMFYTLLIGRPPFDTDTVKNTLNKVV---LADYEMPTFLSIEAKDLIHQLLRRNPADRL 254
Query: 939 TAADLLEDPFIT 950
+ + +L+ PF++
Sbjct: 255 SLSSVLDHPFMS 266
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 108 bits (271), Expect = 3e-23
Identities = 89/279 (31%), Positives = 130/279 (45%), Gaps = 12/279 (4%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQM---NLEKQPKKELIVNEILVMKG-SKHNNIVNF 758
++G+G G Y E+ + + A K + L + +E + EI +M S NIV
Sbjct: 103 ELGRGQFGITYICTEISSGKNFACKSILKRKLIRTKDREDVRREIQIMHYLSGQPNIVEI 162
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
+Y R + +VME EGG L D +T +E + R +K +Q H GVIHRD
Sbjct: 163 KGAYEDRQSVHLVMELCEGGELFDKITKRGHYSEKAAAEIIRSVVKVVQICHFMGVIHRD 222
Query: 818 IKSDNILLSMNGD----IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKV 873
+K +N LLS + +K TDFG I E + +VG+ Y++APEV+ R YG +
Sbjct: 223 LKPENFLLSSKDEASSMLKATDFGVSVFIEEGKVYE-DIVGSAYYVAPEVLKR-NYGKAI 280
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMAMFLNWCLMV 932
DIWS PP+ ET I +P ++S + L
Sbjct: 281 DIWSAGVILYILLCGNPPFWAETDKGIFEEILRGEIDFESEPWPSISESAKDLVRNMLKY 340
Query: 933 DPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKL 971
DP+ R TAA +LE P+I E E + L+RMK+L
Sbjct: 341 DPKKRFTAAQVLEHPWIREGGEASDKPIDSAVLSRMKQL 379
>Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase
Length = 330
Score = 108 bits (271), Expect = 3e-23
Identities = 70/257 (27%), Positives = 123/257 (47%), Gaps = 5/257 (1%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFIDS 761
+G+GA G ++ V K+++L + +KE +NEI+++ +H+NI+ + +
Sbjct: 58 LGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIVILALLQHDNIIAYYNH 117
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
++ L + +EY GG+L D + + E + + + + +H G++HRDI
Sbjct: 118 FMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILHRDI 177
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
K+ NI L+ IKL D+G ++N T+VGTPY+M+PE+ +Y K DIW++
Sbjct: 178 KTLNIFLTKANLIKLGDYGLAKKLNSEYSMAETLVGTPYYMSPELCQGVKYNFKSDIWAV 237
Query: 879 XXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRG 938
+ PL I D S ++ ++ CL DPE R
Sbjct: 238 GCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVDSSQYSLELIQMVHSCLDQDPEQRP 297
Query: 939 TAADLLEDPFITEIAEE 955
TA +LL+ P + + E
Sbjct: 298 TADELLDRPLLRKRRRE 314
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 108 bits (271), Expect = 3e-23
Identities = 75/246 (30%), Positives = 114/246 (45%), Gaps = 10/246 (4%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMN---LEKQPKKELIVNEILVMKGSKHNNIVNFI 759
K+G G G V AY+ + VA+K + +E + I EI +M H NI+
Sbjct: 80 KLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVRIRREIRIMSALNHPNIIQIY 139
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ + + + +VMEY GG L D V+ C L E + + R+ + + H V HRD+
Sbjct: 140 EVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYCHKHRVAHRDL 199
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
K +NILL N + K+ DFG + NL TT G+P + +PE+++ Y GP+VD WS
Sbjct: 200 KLENILLDQNNNAKIADFGLSNYFADKNL-LTTFCGSPLYASPEIINGTPYKGPEVDCWS 258
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
L P+ R + I + + P S M + L V+PE R
Sbjct: 259 LGILLYTLVYGSMPFDGRDFNRMVRQIKRGAYFEPETPSTAS----MLIRNMLRVNPERR 314
Query: 938 GTAADL 943
T D+
Sbjct: 315 ATIFDI 320
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 108 bits (270), Expect = 4e-23
Identities = 75/263 (28%), Positives = 126/263 (47%), Gaps = 20/263 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEI---------LVMKGSKHNN 754
IG+G S V T A+K M + + + E+ ++ + + H +
Sbjct: 30 IGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPH 89
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKGV 813
I+ IDSY +++V + M G L D +T + L+E + ++ R L+ + FLH+ +
Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNI 149
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV------SRK 867
+HRD+K +NILL N I+L+DFGF + E K + GTP ++APE++ +
Sbjct: 150 VHRDLKPENILLDDNMQIRLSDFGFSCHL-EPGEKLRELCGTPGYLAPEILKCSMDETHP 208
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAMF 925
YG +VD+W+ PP+ + + L +I G + P + S +
Sbjct: 209 GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMI-MEGQYQFSSPEWDDRSSTVKDL 267
Query: 926 LNWCLMVDPEDRGTAADLLEDPF 948
++ L VDPE R TA L+ PF
Sbjct: 268 ISRLLQVDPEARLTAEQALQHPF 290
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 108 bits (270), Expect = 4e-23
Identities = 94/299 (31%), Positives = 141/299 (46%), Gaps = 25/299 (8%)
Query: 690 TTGDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK---ELIVNEILV 746
T D S +Y ++G+G G Y ++ T A K ++ +K E + E+ +
Sbjct: 49 TGHDISLMYDLGREVGRGEFGITYLCTDIKTGEKYACKSISKKKLRTAVDIEDVRREVEI 108
Query: 747 MKGS-KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKG 804
MK +H NIV+ D++ + +VME EGG L D +V TE AV + L+
Sbjct: 109 MKHMPRHPNIVSLKDAFEDDDAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTILEV 168
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGD---IKLTDFGFCA------QINEVNLKRTTMVGT 855
+Q H GV+HRD+K +N L + + +K DFG NE+ VG+
Sbjct: 169 VQICHKHGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEGFNEI-------VGS 221
Query: 856 PYWMAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP 915
PY+MAPEV+ R+ YGP+VDIWS PP+ ET I + +DP
Sbjct: 222 PYYMAPEVL-RRNYGPEVDIWSAGVILYILLCGVPPFWAETEQGVAQAIIRSVIDFKRDP 280
Query: 916 -GNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAE-ENTSLAPLVKLARMKKLA 972
+S + L DP+ R +AA +LE +I + N SL VK AR+K+ +
Sbjct: 281 WPRVSETAKDLVRKMLEPDPKKRLSAAQVLEHSWIQNAKKAPNVSLGETVK-ARLKQFS 338
>At4g26890 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 444
Score = 108 bits (270), Expect = 4e-23
Identities = 82/264 (31%), Positives = 136/264 (51%), Gaps = 21/264 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYL 763
IG+G++ V A + A+K +L L+ E ++ ++V +I + L
Sbjct: 11 IGRGSTATVSIAIS-SSGELFAVKSADLSSS---SLLQKEQSILSTLSSPHMVKYIGTGL 66
Query: 764 FRGDLWVV----MEYMEGGSLTDVVTHC--ILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
R +V MEY+ GG+L D++ + L E +I + +R+ L GL +LH +G++H D
Sbjct: 67 TRESNGLVYNILMEYVSGGNLHDLIKNSGGKLPEPEIRSYTRQILNGLVYLHERGIVHCD 126
Query: 818 IKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWS 877
+KS N+L+ NG +K+ D G CA+ ++ ++ GTP +MAPEV +E D+W+
Sbjct: 127 LKSHNVLVEENGVLKIADMG-CAK----SVDKSEFSGTPAFMAPEVARGEEQRFPADVWA 181
Query: 878 LXXXXXXXXXXXPPY--LNETPLRALYLIATNG-TPKLKDPGNLSHKMAMFLNWCLMVDP 934
L P+ LN+ + A+Y I +G +P + P +S K FL CL D
Sbjct: 182 LGCTMIEMMTGSSPWPELNDV-VAAMYKIGFSGESPAI--PAWISDKAKDFLKNCLKEDQ 238
Query: 935 EDRGTAADLLEDPFITEIAEENTS 958
+ R T +LL+ PF+ + E TS
Sbjct: 239 KQRWTVEELLKHPFLDDDEESQTS 262
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 108 bits (269), Expect = 5e-23
Identities = 84/266 (31%), Positives = 126/266 (46%), Gaps = 11/266 (4%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQM---NLEKQPKKELIVNEILVMKG 749
D K Y ++G+G G Y E+GT + A K + L + KE + EI +M+
Sbjct: 75 DIRKFYSLGKELGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQDKEDVKREIQIMQY 134
Query: 750 -SKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQF 807
S NIV +Y R + +VME GG L D ++ +E + R + +Q
Sbjct: 135 LSGQPNIVEIKGAYEDRQSIHLVMELCAGGELFDRIIAQGHYSERAAAGIIRSIVNVVQI 194
Query: 808 LHSKGVIHRDIKSDNILLSM---NGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV 864
H GV+HRD+K +N LLS N +K TDFG I E + R +VG+ Y++APEV+
Sbjct: 195 CHFMGVVHRDLKPENFLLSSKEENAMLKATDFGLSVFIEEGKVYR-DIVGSAYYVAPEVL 253
Query: 865 SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMA 923
R+ YG ++DIWS PP+ E + + +P ++S
Sbjct: 254 -RRSYGKEIDIWSAGVILYILLSGVPPFWAENEKGIFDEVIKGEIDFVSEPWPSISESAK 312
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFI 949
+ L DP+ R TAA +LE P+I
Sbjct: 313 DLVRKMLTKDPKRRITAAQVLEHPWI 338
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 108 bits (269), Expect = 5e-23
Identities = 87/298 (29%), Positives = 148/298 (49%), Gaps = 21/298 (7%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK---ELIVNEILVMKG 749
D S LY ++G+G G Y + A K ++ K ++ E + E+++++
Sbjct: 80 DLSALYDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQH 139
Query: 750 -SKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQF 807
+ NIV F +Y + +L +VME GG L D ++ +E + + R+ + +
Sbjct: 140 LTGQPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFRQIVNVVHV 199
Query: 808 LHSKGVIHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV 864
H GV+HRD+K +N LL N + IK TDFG I E + R +VG+ Y++APEV+
Sbjct: 200 CHFMGVVHRDLKPENFLLVSNEEDSPIKATDFGLSVFIEEGKVYR-DIVGSAYYVAPEVL 258
Query: 865 SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKM 922
R YG ++D+WS PP+ ET + ++ G L+ +S
Sbjct: 259 HR-NYGKEIDVWSAGVMLYILLSGVPPFWGETE-KTIFEAILEGKLDLETSPWPTISESA 316
Query: 923 AMFLNWCLMVDPEDRGTAADLLEDPFITE--IAEENTSLAPLVKLA------RMKKLA 972
+ L+ DP+ R TAA+ LE P++T+ I+++ + A LV++ ++KKLA
Sbjct: 317 KDLIRKMLIRDPKKRITAAEALEHPWMTDTKISDKPINSAVLVRMKQFRAMNKLKKLA 374
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 108 bits (269), Expect = 5e-23
Identities = 83/277 (29%), Positives = 135/277 (47%), Gaps = 14/277 (5%)
Query: 692 GDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIK-----QMNLEKQPKKELIVNEILV 746
G+ + +YK + +G+G V A + T VAIK Q+N + K + E+ +
Sbjct: 92 GNGNGVYKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQK---LYREVKI 148
Query: 747 MKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGL 805
MK H NIV L++VMEY G L D +V + + E + R+ + +
Sbjct: 149 MKLLNHPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAI 208
Query: 806 QFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV-V 864
Q+ HSK V+HRD+K++N+LL + +IK+ DFGF + N + T G+P + APE+ +
Sbjct: 209 QYCHSKFVVHRDLKAENLLLDQHMNIKIADFGF-GNTFDPNAQLETFCGSPPYAAPELFM 267
Query: 865 SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAM 924
RK GP+VD WSL P+ T L+ L G K + P +S
Sbjct: 268 GRKYAGPEVDAWSLGVVLYTLVSGSLPFDGGT-LKELRERVLRG--KYRVPYYISMDCEN 324
Query: 925 FLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAP 961
+ L+++P R + + ++ D +I +E+ L P
Sbjct: 325 LMRKFLVLNPAKRTSLSAVMSDKWINLGHDESDRLRP 361
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 107 bits (268), Expect = 7e-23
Identities = 80/280 (28%), Positives = 137/280 (48%), Gaps = 26/280 (9%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNL---------EKQPKKELIVNEI-LVMKGSKHN 753
+G+G S V T+ A+K +++ E + +E + E+ ++ K S H
Sbjct: 26 LGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVSGHP 85
Query: 754 NIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKG 812
NI+ D+Y ++V + M+ G L D +T + L+E + + R L+ + LH
Sbjct: 86 NIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLN 145
Query: 813 VIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV------SR 866
++HRD+K +NILL N +IKLTDFGF Q+ E + + GTP ++APE++
Sbjct: 146 IVHRDLKPENILLDDNMNIKLTDFGFSCQL-EPGERLREVCGTPSYLAPEIIECSMNEDH 204
Query: 867 KEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATN----GTPKLKDPGNLSHKM 922
YG +VD+WS PP+ + + L +I + G+P+ D S +
Sbjct: 205 PGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDD---YSDTV 261
Query: 923 AMFLNWCLMVDPEDRGTAADLLEDPFITE-IAEENTSLAP 961
++ L+V P++R TA + L PF + + EE +P
Sbjct: 262 KDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSP 301
>Hs21729899 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 258
Score = 107 bits (268), Expect = 7e-23
Identities = 75/241 (31%), Positives = 118/241 (48%), Gaps = 18/241 (7%)
Query: 729 MNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI 788
+ L+KQ EL EIL S + I+ F ++ + + E+M+GGSL DV
Sbjct: 13 LELQKQIMSEL---EILYKCDSSY--IIGFYGAFFVENRISICTEFMDGGSL-DVYRK-- 64
Query: 789 LTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLK 848
+ E +G ++ +KGL +L S ++HRD+K N+L++ G +KL DFG Q+ VN
Sbjct: 65 MPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQL--VNSI 122
Query: 849 RTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYL-------NETPLRAL 901
T VGT +MAPE +S ++YG D+WSL PY + PL+ L
Sbjct: 123 AKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLL 182
Query: 902 YLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAP 961
I +P L G S F+ C+ P++R +L+ PFI + + N ++
Sbjct: 183 QCIVDEDSPVL-PVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVS 241
Query: 962 L 962
+
Sbjct: 242 M 242
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 107 bits (268), Expect = 7e-23
Identities = 78/274 (28%), Positives = 133/274 (48%), Gaps = 29/274 (10%)
Query: 704 IGQGASGGVYTAYELGTNASVAIK--------QMNLEKQPKKELIVN------EILVMKG 749
+G+G G V+ + E T +A+K Q+ + Q K+E+ + IL + G
Sbjct: 50 LGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYG 109
Query: 750 SKHNNIVNFID-SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFL 808
H++ F+ Y RG+L+ V++ G + +V+ G R+ L +
Sbjct: 110 YFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIA---------GRFVRQLANALHYC 160
Query: 809 HSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE 868
HSKGVIHRDIK +N+LL ++KL DFG+ + + KR T+ GT ++APE+VS +
Sbjct: 161 HSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVAD--HSKRHTLCGTMDYLAPEMVSNQP 218
Query: 869 YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNW 928
+ VDIW++ P+ N+T + LIA K+ P ++ A +N
Sbjct: 219 HDFNVDIWAIGILLFEMLVGYAPFANQTGDK---LIARIKECKIYIPSVVTDGAASLINA 275
Query: 929 CLMVDPEDRGTAADLLEDPFITEIAEENTSLAPL 962
+ +P++R D++ P+I E+ + PL
Sbjct: 276 IIKKEPQERLPLVDIMAHPWIKEMKQREDIEVPL 309
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 107 bits (268), Expect = 7e-23
Identities = 86/298 (28%), Positives = 145/298 (47%), Gaps = 33/298 (11%)
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASVAIK----QMNLEKQPKKEL-----IVNEIL 745
+K Y K+G GA G V Y+ T A+K M +P ++NE
Sbjct: 154 NKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAK 213
Query: 746 VMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKG 804
+MK H +V D +++V+E+M GG L + ++++ +L+E +
Sbjct: 214 IMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHA 273
Query: 805 LQFLHSKGVIHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
+++LH +G+ HRD+K DN+LL N + +K++DFG + + ++ R T+ GTP ++AP
Sbjct: 274 VKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMR-TLCGTPLYVAP 332
Query: 862 EVV---SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATN----GTPKLKD 914
EV+ R+ Y KVDIWSL P+ +E A I G P K
Sbjct: 333 EVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWK- 391
Query: 915 PGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLV-KLARMKKL 971
++S + + +N L+VDPE R + D+L+ ++ + AP++ K R+ KL
Sbjct: 392 --SVSQRAKLLINQMLIVDPERRPSIDDVLQSSWLRD--------APMLQKAKRLMKL 439
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 107 bits (267), Expect = 9e-23
Identities = 76/279 (27%), Positives = 132/279 (47%), Gaps = 15/279 (5%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-------QPKKELIVNEILVMKGS 750
Y+ + +G G V A E+ + AIK +N K + E+ EI ++K
Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226
Query: 751 KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLH 809
H +V + + +L++VMEY+EGG L D ++ + + E + ++ L+ L LH
Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH 286
Query: 810 SKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE- 868
+GV HRDIK +NIL++ + +K++DFG I+ T GT ++APEV+ K
Sbjct: 287 KQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNV 346
Query: 869 -----YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTP-KLKDPGNLSHKM 922
Y KVDIWSL P+ + + + + LI+ P + +S +
Sbjct: 347 NLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEG 406
Query: 923 AMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAP 961
+N L ++PE R + ++ L+ P+ ++ P
Sbjct: 407 IDLINRMLEINPEKRISESEALQHPWFYTVSTHEHRTPP 445
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 107 bits (267), Expect = 9e-23
Identities = 91/285 (31%), Positives = 132/285 (45%), Gaps = 31/285 (10%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEK---------QPKKELIVNEILVMKGSKHNN 754
+G GA G V A+E T VAIK ++ K P + EI ++K H
Sbjct: 226 LGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALN-VETEIEILKKLNHPC 284
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGV 813
I+ I ++ D ++V+E MEGG L D VV + L E + L +Q+LH G+
Sbjct: 285 IIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGI 343
Query: 814 IHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEV---VSRK 867
IHRD+K +N+LLS + IK+TDFG + E +L R T+ GTP ++APEV V
Sbjct: 344 IHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMR-TLCGTPTYLAPEVLVSVGTA 402
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAMF 925
Y VD WSL PP+ +L T+G +S K
Sbjct: 403 GYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDL 462
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITE----------IAEENTSLA 960
+ L+VDP+ R T + L P++ + ++EEN S A
Sbjct: 463 VKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTA 507
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 107 bits (267), Expect = 9e-23
Identities = 85/277 (30%), Positives = 128/277 (45%), Gaps = 11/277 (3%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN---EILVMKG-SKHNNIVNF 758
++G+G G Y T VA K + + K+ I + E+ +M S H NIV+
Sbjct: 83 ELGRGQFGVTYLVTHKETKQQVACKSIPTRRLVHKDDIEDVRREVQIMHHLSGHRNIVDL 142
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
+Y R + ++ME EGG L D +++ + +E + R+ + + HS GV+HRD
Sbjct: 143 KGAYEDRHSVNLIMELCEGGELFDRIISKGLYSERAAADLCRQMVMVVHSCHSMGVMHRD 202
Query: 818 IKSDNILL---SMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
+K +N L N +K TDFG + K +VG+ Y++APEV+ R YGP+ D
Sbjct: 203 LKPENFLFLSKDENSPLKATDFGLSVFFKPGD-KFKDLVGSAYYVAPEVLKRN-YGPEAD 260
Query: 875 IWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGN-LSHKMAMFLNWCLMVD 933
IWS PP+ E I DP LS + L D
Sbjct: 261 IWSAGVILYILLSGVPPFWGENETGIFDAILQGQLDFSADPWPALSDGAKDLVRKMLKYD 320
Query: 934 PEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKK 970
P+DR TAA++L P+I E E + L+RMK+
Sbjct: 321 PKDRLTAAEVLNHPWIREDGEASDKPLDNAVLSRMKQ 357
>At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 545
Score = 107 bits (267), Expect = 9e-23
Identities = 86/272 (31%), Positives = 126/272 (45%), Gaps = 16/272 (5%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK---ELIVNEILVMKG-SKHNNIVNF 758
++G+G G Y + T+ ++A K ++ K E + E+ +M +H N+V
Sbjct: 68 ELGRGEFGITYLCTDRETHEALACKSISKRKLRTAVDIEDVRREVAIMSTLPEHPNVVKL 127
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
SY ++ +VME EGG L D +V TE AV+R + + HS GV+HRD
Sbjct: 128 KASYEDNENVHLVMELCEGGELFDRIVARGHYTERAAAAVARTIAEVVMMCHSNGVMHRD 187
Query: 818 IKSDNILLS---MNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
+K +N L + N +K DFG + K T +VG+PY+MAPEV+ R +YGP VD
Sbjct: 188 LKPENFLFANKKENSPLKAIDFGLSVFFKPGD-KFTEIVGSPYYMAPEVLKR-DYGPGVD 245
Query: 875 IWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMAMFLNWCLMVD 933
+WS PP+ ET I +DP +S + L D
Sbjct: 246 VWSAGVIIYILLCGVPPFWAETEQGVALAILRGVLDFKRDPWPQISESAKSLVKQMLDPD 305
Query: 934 PEDRGTAADLLEDPFITEIAEENTSLAPLVKL 965
P R TA +L P+I +N AP V L
Sbjct: 306 PTKRLTAQQVLAHPWI-----QNAKKAPNVPL 332
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 107 bits (267), Expect = 9e-23
Identities = 74/227 (32%), Positives = 119/227 (51%), Gaps = 10/227 (4%)
Query: 694 PSKLYKNLIK---IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELI--VNEILVMK 748
P K+ +K +GQG G V+ A + T +VAIK++ L KQ + I + EI ++K
Sbjct: 5 PKKVADRYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLK 64
Query: 749 GSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVV--THCILTEGQIGAVSRETLKGLQ 806
KH +I+ ID++ + +L +V E+ME L V+ ++ L+ I + T KGL
Sbjct: 65 ELKHPHIILLIDAFPHKENLHLVFEFMET-DLEAVIRDSNIFLSPADIKSYLLMTFKGLA 123
Query: 807 FLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-S 865
+ H K V+HRD+K +N+L+ ++G +KL DFG N K T V ++ APE++
Sbjct: 124 YCHDKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFG 183
Query: 866 RKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRAL-YLIATNGTPK 911
K+YG VD+W++ P + + L + A GTPK
Sbjct: 184 AKQYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPK 230
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 107 bits (267), Expect = 9e-23
Identities = 68/251 (27%), Positives = 120/251 (47%), Gaps = 8/251 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMN---LEKQPKKELIVNEILVMKGSKHNNIVNFID 760
+G+G VY A L T+ VAIK ++ ++ + E+ + KH +++
Sbjct: 20 LGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYT 79
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCI--LTEGQIGAVSRETLKGLQFLHSKGVIHRDI 818
+ +++V+E G L + H TE + ++ ++ + GL +LHS ++HRDI
Sbjct: 80 FFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDI 139
Query: 819 KSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
N+LLS +K+ DFG Q+ + + TM GTP +++PEVVSR +G D+WS+
Sbjct: 140 SLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSV 199
Query: 879 XXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRG 938
PP+ + L + + + P +LS++ +N L P +R
Sbjct: 200 GCMLYTLLVGRPPFETDAVQSTLNKVVMS---EYIMPAHLSYEAQDLINKLLKKLPHERI 256
Query: 939 TAADLLEDPFI 949
T +L PF+
Sbjct: 257 TLEAVLCHPFM 267
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 107 bits (266), Expect = 1e-22
Identities = 82/259 (31%), Positives = 122/259 (46%), Gaps = 21/259 (8%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQP-------KKELIVNEILVMKGSKHNNIV 756
+G+G G V Y+ + VAIKQ+N + K I NE+ VMK H NIV
Sbjct: 175 LGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIQNEVEVMKKLSHPNIV 234
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGA-----VSRETLKGLQFLHSK 811
D ++V+EY+ GG + + +G + + + + +LHS
Sbjct: 235 AIYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKYFAFQLIDAVLYLHSV 294
Query: 812 GVIHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRK- 867
G+ HRDIK +NIL S + +KLTDFG N VN + T GTP + APE+V+ +
Sbjct: 295 GICHRDIKPENILCSNKAERCILKLTDFGMAK--NSVN-RMKTHCGTPSYCAPEIVANQG 351
Query: 868 -EYGPKVDIWSLXXXXXXXXXXXPPYLNE-TPLRALYLIATNGTPKLKDPGNLSHKMAMF 925
EY PKVDIWSL PP+ E T L+ + T + ++ +
Sbjct: 352 VEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDLKMDEQVLTGRLFFHEQWHRITDETQNM 411
Query: 926 LNWCLMVDPEDRGTAADLL 944
+ W L V+P R +A +L+
Sbjct: 412 IQWMLTVEPLIRPSAVELM 430
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 107 bits (266), Expect = 1e-22
Identities = 76/251 (30%), Positives = 122/251 (48%), Gaps = 9/251 (3%)
Query: 704 IGQGASGGVYTAYEL---GTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFID 760
+G GA VY A +L G + ++ + Q K + EI VM+ +H +IV +
Sbjct: 34 LGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKREISVMRRLRHPHIVLLSE 93
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ VME +GG L VT TE R+ + +++ H++GV HRD+K
Sbjct: 94 VLATKTKIYFVMELAKGGELFSRVTSNRFTESLSRKYFRQLISAVRYCHARGVFHRDLKP 153
Query: 821 DNILLSMNGDIKLTDFGFCAQINEVNLKRT--TMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
+N+LL N D+K++DFG A +++ T+ GTP ++APE++ +K Y G K DIWS
Sbjct: 154 ENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDGSKADIWS 213
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
P+ + + LY KL P S + L L +PE R
Sbjct: 214 CGVVLFLLNAGYLPF-RDPNIMGLYRKIHKAQYKL--PDWTSSDLRKLLRRLLEPNPELR 270
Query: 938 GTAADLLEDPF 948
T ++L+DP+
Sbjct: 271 ITVEEILKDPW 281
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 107 bits (266), Expect = 1e-22
Identities = 78/274 (28%), Positives = 133/274 (48%), Gaps = 8/274 (2%)
Query: 692 GDPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLE--KQPKKELIVNEILVMKG 749
G+ +YK + +G+G V A L T VAIK ++ ++ + E+ +MK
Sbjct: 57 GNGYGVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYREVNIMKK 116
Query: 750 SKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFL 808
H NIV + L++VMEY+ GG L + +V + + E + R+ + +++
Sbjct: 117 LNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYC 176
Query: 809 HSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKE 868
HSK ++HRD+K++N+LL +K+ DFGF E T G+P + APE+ K+
Sbjct: 177 HSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTF-EPKAPLETFCGSPPYAAPELFRGKK 235
Query: 869 Y-GPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLN 927
Y GP+VD WSL P+ + T L+ L G K + P +S + +
Sbjct: 236 YSGPEVDSWSLGVVLYTLVSGSLPF-DGTNLKELRDRVLRG--KYRVPYYVSIECESLIR 292
Query: 928 WCLMVDPEDRGTAADLLEDPFITEIAEENTSLAP 961
L+++P R + + ++ D +I E+ L P
Sbjct: 293 KFLVLNPTQRTSLSAVMADRWINMGYEQGNGLRP 326
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 107 bits (266), Expect = 1e-22
Identities = 77/263 (29%), Positives = 124/263 (46%), Gaps = 12/263 (4%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEK-QPKKELIVNEILVMKGSKHNNIV 756
YK IG G V E T A+K + K + K+ +I NE+ +++ KH NIV
Sbjct: 46 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV 105
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIH 815
I+ +L++VME ++GG L D +T TE + +++LHS ++H
Sbjct: 106 LLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVH 165
Query: 816 RDIKSDNILLSMNGD----IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGP 871
RDIK +N+L+ + D +KL DFG ++ T+ GTP ++APE+++ YG
Sbjct: 166 RDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAETGYGL 222
Query: 872 KVDIWSLXXXXXXXXXXXPPYLNE-TPLRALYLIATNGTPKLKDP--GNLSHKMAMFLNW 928
KVDIW+ PP+ L+ G P N+S +
Sbjct: 223 KVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITM 282
Query: 929 CLMVDPEDRGTAADLLEDPFITE 951
L+VD + R +A +LE P++ +
Sbjct: 283 MLLVDVDQRFSAVQVLEHPWVND 305
>Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 291
Score = 107 bits (266), Expect = 1e-22
Identities = 72/261 (27%), Positives = 127/261 (48%), Gaps = 16/261 (6%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNL------EKQPKKELIVNEILVMKGSKHNNIV 756
+IG GA Y A ++GT +A+KQ+ E++ E + EI +M H NI+
Sbjct: 25 QIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNII 84
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGVIH 815
+ + + + + +E+M GGS+ +++ + E + + + L+GL +LH +IH
Sbjct: 85 RMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIH 144
Query: 816 RDIKSDNILLSMNGD-IKLTDFGFCAQINEVNLK----RTTMVGTPYWMAPEVVSRKEYG 870
RD+K N+L+ G +++ DFG A++ + ++GT +MAPEV+ ++YG
Sbjct: 145 RDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYG 204
Query: 871 PKVDIWSLXXXXXXXXXXXPPYLNETPLRALYL----IATNGTPKLKDPGNLSHKMAMFL 926
D+WS+ PP+ E L L I + T P +LS +
Sbjct: 205 RSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKVIIASATTAPSIPSHLSPGLRDVA 264
Query: 927 NWCLMVDPEDRGTAADLLEDP 947
CL + P+DR + +LL+ P
Sbjct: 265 LRCLELQPQDRPPSRELLKHP 285
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 106 bits (265), Expect = 2e-22
Identities = 82/289 (28%), Positives = 131/289 (44%), Gaps = 9/289 (3%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL-IVNEILVMKGSK 751
D K+++ +G GA V A E T A+K + + KE I NEI V++ K
Sbjct: 18 DIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIK 77
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHS 810
H NIV D Y L++VM+ + GG L D +V TE + R+ L + +LH
Sbjct: 78 HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHR 137
Query: 811 KGVIHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRK 867
G++HRD+K +N+L + I ++DFG + ++ +T GTP ++APEV+++K
Sbjct: 138 MGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVM-STACGTPGYVAPEVLAQK 196
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAMF 925
Y VD WS+ PP+ +E + L+ + P ++S F
Sbjct: 197 PYSKAVDCWSIGVIAYILLCGYPPFYDENDSK-LFEQILKAEYEFDSPYWDDISDSAKDF 255
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAES 974
+ + DP R T P+I N ++ V K A+S
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKS 304
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 106 bits (265), Expect = 2e-22
Identities = 89/293 (30%), Positives = 138/293 (46%), Gaps = 16/293 (5%)
Query: 693 DPSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQM---NLEKQPKKELIVNEILVMKG 749
D K Y ++G+G G Y E+GT A K + L + +E + EI +M+
Sbjct: 64 DIRKFYSLGRELGRGGLGITYMCKEIGTGNIYACKSILKRKLISELGREDVKTEIQIMQH 123
Query: 750 -SKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQF 807
S N+V SY R + +VME GG L D ++ +E + + +Q
Sbjct: 124 LSGQPNVVEIKGSYEDRHSVHLVMELCAGGELFDRIIAQGHYSERAAAGTIKSIVDVVQI 183
Query: 808 LHSKGVIHRDIKSDNILLSM---NGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV 864
H GVIHRD+K +N L S N +K+TDFG A I E + + +VG+PY++APEV+
Sbjct: 184 CHLNGVIHRDLKPENFLFSSKEENAMLKVTDFGLSAFIEEGKIYK-DVVGSPYYVAPEVL 242
Query: 865 SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMA 923
R+ YG ++DIWS PP+ + I +++P ++S
Sbjct: 243 -RQSYGKEIDIWSAGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPSISDSAK 301
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFI-----TEIAEENTSLAPLVKLARMKKL 971
+ L DP+ R TAA +LE P+I E ++T L+ + + M KL
Sbjct: 302 DLVEKMLTEDPKRRITAAQVLEHPWIKGGEAPEKPIDSTVLSRMKQFRAMNKL 354
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 106 bits (264), Expect = 2e-22
Identities = 66/190 (34%), Positives = 105/190 (54%), Gaps = 7/190 (3%)
Query: 694 PSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELI--VNEILVMKGSK 751
P Y+ + +IG+G G VY A T VA+K++ LE++ I V E+ +++ +
Sbjct: 273 PKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLR 332
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCIL--TEGQIGAVSRETLKGLQFLH 809
H NIV ++ + + +++V EYM+ LT V+ + L T G I +S++ + L +LH
Sbjct: 333 HKNIVRLLEIMVEKSSVYMVFEYMDH-DLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLH 391
Query: 810 SKGVIHRDIKSDNILLSMNGDIKLTDFGFCA-QINEVNLKRTTMVGTPYWMAPE-VVSRK 867
+GV+HRDIK NILL+ NGD+K DFG + + T V T ++ PE ++
Sbjct: 392 HRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGET 451
Query: 868 EYGPKVDIWS 877
Y VDIWS
Sbjct: 452 AYDTAVDIWS 461
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 106 bits (264), Expect = 2e-22
Identities = 78/274 (28%), Positives = 134/274 (48%), Gaps = 10/274 (3%)
Query: 693 DPSKLYKNLIK--IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGS 750
DP K IK IG+G+ V T AIK + + + +E+ +E+ V++
Sbjct: 91 DPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRV 150
Query: 751 KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLH 809
+H NI+ ++ + + +++VME GG L D ++ TE V + L G+++LH
Sbjct: 151 RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLH 210
Query: 810 SKGVIHRDIKSDNILL---SMNGDIKLTDFGFCAQINEVN--LKRTTMVGTPYWMAPEVV 864
+ G+ HRD+K +N+L + I +TDFG + + + L +TT GTP ++APEV+
Sbjct: 211 ALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTT-CGTPEYIAPEVL 269
Query: 865 SRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMA 923
RK Y VD+W+L P+ ++ R I +P ++S+
Sbjct: 270 VRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAK 329
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFITEIAEENT 957
F++ L VDP R TA L P++ +A ++
Sbjct: 330 DFIDRLLTVDPGARMTALQALRHPWVVSMAASSS 363
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 106 bits (264), Expect = 2e-22
Identities = 64/256 (25%), Positives = 129/256 (50%), Gaps = 8/256 (3%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSY 762
++G+GA G VY A E T + A K + + KKE +++EI +M H ++N +++
Sbjct: 200 ELGKGAYGTVYRATEKATGKTWAAKMVQVRPGVKKENVIHEISMMNQLHHEKLLNLHEAF 259
Query: 763 LFRGDLWVVMEYMEGGSLTDVVTH--CILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
++W++ E++ GG L + + +++E ++ + L G+ +H ++H D+K
Sbjct: 260 DMGNEMWLIEEFVSGGELFEKILEDDSLMSEEEVRDYMHQILLGVSHMHKNQIVHLDLKP 319
Query: 821 DNILLSM--NGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSL 878
+NILL + ++K+ DFG +++ + + GTP + APEVV+ + G D+W++
Sbjct: 320 ENILLKAKNSNELKIIDFGLARKLDPKKSVK-LLFGTPEFCAPEVVNYQPVGLSTDMWTV 378
Query: 879 XXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPG--NLSHKMAMFLNWCLMVDPED 936
P+L ++ L ++ + DP ++S F+ ++ D
Sbjct: 379 GVISYVLLSGLSPFLGDSDEDTLANVSASDW-DFDDPSWDDVSDLAKDFICRLMIKDKRK 437
Query: 937 RGTAADLLEDPFITEI 952
R + D L P+IT++
Sbjct: 438 RMSVQDALRHPWITKM 453
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 106 bits (264), Expect = 2e-22
Identities = 72/250 (28%), Positives = 124/250 (48%), Gaps = 11/250 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN---EILVMKGSKHNNIVNFID 760
+G G VY A + + VAIK ++ EK K L+ + EI +++ +H IV+ +
Sbjct: 80 LGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFE 139
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ ++ VMEY+ GG L + V L E ++ + + F H +GV HRD+K
Sbjct: 140 VMATKSKIYFVMEYVGGGELFNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKP 199
Query: 821 DNILLSMNGDIKLTDFGFCA---QINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIW 876
+N+LL G++K++DFG A Q+ + L T GTP ++APEV++RK Y K D+W
Sbjct: 200 ENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCH-TFCGTPAYIAPEVLTRKGYDAAKADVW 258
Query: 877 SLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPED 936
S P+ ++ + +Y G + + P S + L L +P+
Sbjct: 259 SCGVILFVLMAGHIPFYDKN-IMVMYKKIYKG--EFRCPRWFSSDLVRLLTRLLDTNPDT 315
Query: 937 RGTAADLLED 946
R T +++++
Sbjct: 316 RITIPEIMKN 325
>At1g23700 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 473
Score = 106 bits (264), Expect = 2e-22
Identities = 89/268 (33%), Positives = 126/268 (46%), Gaps = 20/268 (7%)
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK-ELIVNEILVMKGSKHN 753
+K Y+ L +IG G VY A + + VAIK NLEK E I E+ + H
Sbjct: 13 AKDYEILEEIGDG----VYRARCILLDEIVAIKIWNLEKCTNDLETIRKEVHRLSLIDHP 68
Query: 754 NIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI---LTEGQIGAVSRETLKGLQFLHS 810
N++ S++ LW+VM +M GS +++ L E I + RE LK L +LH
Sbjct: 69 NLLRVHCSFIDSSSLWIVMPFMSCGSSLNIMKSVYPNGLEEPVIAILLREILKALVYLHG 128
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQI-NEVNLKRT----TMVGTPYWMAPEVVS 865
G IHR++K+ N+L+ G +KL DF A + + V RT T VG P MAPE
Sbjct: 129 LGHIHRNVKAGNVLVDSEGTVKLGDFEVSASMFDSVERMRTSSENTFVGNPRRMAPEKDM 188
Query: 866 RK--EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMA 923
++ Y KVDIWS P PL + + P ++ S
Sbjct: 189 QQVDGYDFKVDIWSFGMTALELAHGHSP-TTVLPLN----LQNSPFPNYEEDTKFSKSFR 243
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFITE 951
+ CL+ DPE R TA+ LLE PF+ +
Sbjct: 244 ELVAACLIEDPEKRPTASQLLEYPFLQQ 271
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 105 bits (263), Expect = 3e-22
Identities = 69/233 (29%), Positives = 124/233 (52%), Gaps = 7/233 (3%)
Query: 720 TNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGS 779
++ S+A ++ + Q I EI++MK H N++ + + + +L++V+EY++GG
Sbjct: 141 SSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGE 200
Query: 780 LTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNILL-SMNGDIKLTDFG 837
L D +V+ L E + ++ ++G+ + HS + HRD+K +N+LL N IK+ DFG
Sbjct: 201 LFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFG 260
Query: 838 FCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWSLXXXXXXXXXXXPPYLNET 896
A + N T G+P++ +PE+V + Y G D+WS P+ N+
Sbjct: 261 MAA-LELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPF-NDD 318
Query: 897 PLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFI 949
++ L L +G K + P NLS + ++ L++DPE R T ++L+ P I
Sbjct: 319 NIKKLLLKVQSG--KYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLI 369
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 105 bits (263), Expect = 3e-22
Identities = 82/259 (31%), Positives = 120/259 (45%), Gaps = 21/259 (8%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQP-------KKELIVNEILVMKGSKHNNIV 756
+G+G G V Y+ + VAIKQ+N + K I NE+ VMK H NIV
Sbjct: 176 LGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIRNEVEVMKKLSHPNIV 235
Query: 757 NFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGA-----VSRETLKGLQFLHSK 811
D ++V+EY+ GG V +G + + + + +LHS
Sbjct: 236 AIYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYNRMGLGESLGKYFAFQLIDAILYLHSV 295
Query: 812 GVIHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRK- 867
G+ HRDIK +NIL S + +KLTDFG N VN + T GTP + APE+V+ +
Sbjct: 296 GICHRDIKPENILCSDKAERCILKLTDFGMAK--NSVN-RMKTRCGTPSYNAPEIVANEG 352
Query: 868 -EYGPKVDIWSLXXXXXXXXXXXPPYLNE-TPLRALYLIATNGTPKLKDPGNLSHKMAMF 925
EY PKVDIWSL PP+ E T + + T ++ +
Sbjct: 353 VEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDMTMDEQVLTGRLIFHAQWRRITVETQNM 412
Query: 926 LNWCLMVDPEDRGTAADLL 944
+ W L V+P +R +A +L+
Sbjct: 413 IKWMLTVEPSNRPSAVELM 431
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 105 bits (262), Expect = 3e-22
Identities = 78/284 (27%), Positives = 141/284 (49%), Gaps = 22/284 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK--ELIVNEILVMKGSKHNNIVNFIDS 761
+G+G+ G V A + T AIK++N EK +L+ E+ ++K KH +I++
Sbjct: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ +++VME E G L +++ +E + + + + +LH+ ++HRD+K
Sbjct: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
Query: 821 DNILLS---------MNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYWMAPEVVSRKE 868
+NI++ +N +IK+TDFG + +E L+ T GTP +MAPEV+S +
Sbjct: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATC--GTPIYMAPEVISAHD 299
Query: 869 YGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAMFL 926
Y + DIWS+ PP+L + L+ + G ++ ++S L
Sbjct: 300 YSQQCDIWSIGVVMYMLLRGEPPFLASSE-EKLFELIRKGELHFENAVWNSISDCAKSVL 358
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKK 970
+ VDP R TA +LL++ ++T + +S+ P L MK+
Sbjct: 359 KQLMKVDPAHRITAKELLDNQWLT--GNKLSSVRPTNVLEMMKE 400
>Hs14589900 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 334
Score = 105 bits (262), Expect = 3e-22
Identities = 78/279 (27%), Positives = 139/279 (48%), Gaps = 18/279 (6%)
Query: 701 LIKIGQGASGGVYTAYELGTNASVAIKQMN--LEKQPKKELIVNEILVMKGSKHNNIVNF 758
++++G+GA G V + + +A+K++ + Q +K L+++ + M+ V F
Sbjct: 56 IMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTF 115
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQ------IGAVSRETLKGLQFLHSK- 811
+ GD+W+ ME M+ + D ++ +GQ +G ++ +K L+ LHSK
Sbjct: 116 YGALFREGDVWICMELMD--TSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKL 173
Query: 812 GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV----SRK 867
VIHRD+K N+L++ G +K+ DFG + + ++ +T G +MAPE + ++K
Sbjct: 174 SVIHRDVKPSNVLINALGQVKMCDFGISGYLVD-SVAKTIDAGCKPYMAPERINPELNQK 232
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDPGNLSHKMAMFL 926
Y K DIWSL PY + TP + L + +P+L S + F
Sbjct: 233 GYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQL-PADKFSAEFVDFT 291
Query: 927 NWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKL 965
+ CL + ++R T +L++ PF T + T +A VKL
Sbjct: 292 SQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKL 330
>CE07737 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1418
Score = 105 bits (262), Expect = 3e-22
Identities = 80/268 (29%), Positives = 126/268 (46%), Gaps = 17/268 (6%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYL 763
I G+ G V+ A ++ ++ +A K M ++++ K I +EI + + H N+V + +
Sbjct: 1131 IASGSFGSVHRAMDIDSHRVIAAKVMRIQRENHKA-IESEINIFRQLIHENLVKYYGVQV 1189
Query: 764 FRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNI 823
D+ + MEY G+L + + H + + + L+ +Q+LHS +IHRDIK NI
Sbjct: 1190 EDSDVIIFMEYCSQGTL-ERICHGKMDLKMVRQYTNSLLRAVQYLHSHKIIHRDIKPANI 1248
Query: 824 LLSMNGDIKLTDFGFCAQINE---VNLKRTTMVGTPYWMAPEVVSRKE----------YG 870
L +KL DFG +++ E V + T GTP +MAPE+ S E YG
Sbjct: 1249 FLDKCTVLKLGDFGCSSRLVESSTVYGEFQTTAGTPQFMAPEIYSYGEKDETTGSYSGYG 1308
Query: 871 PKVDIWSLXXXXXXXXXXXPPYLNETPLR-ALYLIATNGTPKLKDPGNLSHKMAMFLNWC 929
VDIW+L P+ +T + A L P D + + F + C
Sbjct: 1309 RSVDIWALGATVVNMMTGKVPFEGQTRHQIAFALCFRKQKPTYPDIADKRPDVKRFFDNC 1368
Query: 930 LMVDPEDRGTAADLLEDPFI-TEIAEEN 956
P DR TAA+LL+ F I +EN
Sbjct: 1369 FEFLPNDRPTAAELLQTTFANVNITDEN 1396
>At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 348
Score = 105 bits (262), Expect = 3e-22
Identities = 74/255 (29%), Positives = 126/255 (49%), Gaps = 12/255 (4%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQM--NLEKQPKKELIVNEILVMKGSKHNNIVNFID 760
+IG GA G VY T+ A+K + N E +++ I EI +++ H N+V D
Sbjct: 75 RIGSGAGGTVYKVIHTPTSRPFALKVIYGNHEDTVRRQ-ICREIEILRSVDHPNVVKCHD 133
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKS 820
+ G++ V++E+M+ GSL I E ++ +SR+ L GL +LH + ++HRDIK
Sbjct: 134 MFDHNGEIQVLLEFMDQGSLEGAH---IWQEQELADLSRQILSGLAYLHRRHIVHRDIKP 190
Query: 821 DNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR-----KEYGPKVDI 875
N+L++ ++K+ DFG + + + VGT +M+PE ++ + G D+
Sbjct: 191 SNLLINSAKNVKIADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNHGRYDGYAGDV 250
Query: 876 WSLXXXXXXXXXXXPPY-LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDP 934
WSL P+ ++ A + A + + P S + F++ CL DP
Sbjct: 251 WSLGVSILEFYLGRFPFAVSRQGDWASLMCAICMSQPPEAPATASQEFRHFVSCCLQSDP 310
Query: 935 EDRGTAADLLEDPFI 949
R +A LL+ PFI
Sbjct: 311 PKRWSAQQLLQHPFI 325
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 105 bits (262), Expect = 3e-22
Identities = 79/279 (28%), Positives = 127/279 (45%), Gaps = 15/279 (5%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNIVNFIDS 761
+GQG+ G VY A + VAIK ++ + KEL + E + KH +++ I+S
Sbjct: 10 VGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKNLRRECDIQARLKHPHVIEMIES 69
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSD 821
+ + DL+VV E+ + + + E V+ + L +LHS ++HRD+K
Sbjct: 70 FESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKPQ 129
Query: 822 NILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLXXX 881
N+LL N KL DFG + T++ GTP +MAPE+++ + Y D+WSL
Sbjct: 130 NVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCI 189
Query: 882 XXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAA 941
PP+ + L+L+ +K P L+ + FL L DP R +
Sbjct: 190 AYESMAGQPPFCASS---ILHLVKMIKHEDVKWPSTLTSECRSFLQGLLEKDPGLRISWT 246
Query: 942 DLLEDPFI----------TEIAEENTSLAPLVKLARMKK 970
LL PF+ E A+E+ P K+ K+
Sbjct: 247 QLLCHPFVEGRIFIAETQAEAAKESPFTNPEAKVKSSKQ 285
>Hs14589902 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 278
Score = 105 bits (261), Expect = 5e-22
Identities = 78/278 (28%), Positives = 138/278 (49%), Gaps = 18/278 (6%)
Query: 702 IKIGQGASGGVYTAYELGTNASVAIKQMN--LEKQPKKELIVNEILVMKGSKHNNIVNFI 759
+++G+GA G V + + +A+K++ + Q +K L+++ + M+ V F
Sbjct: 1 MELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFY 60
Query: 760 DSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQ------IGAVSRETLKGLQFLHSK-G 812
+ GD+W+ ME M+ + D ++ +GQ +G ++ +K L+ LHSK
Sbjct: 61 GALFREGDMWICMELMD--TSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLS 118
Query: 813 VIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV----SRKE 868
VIHRD+K N+L++ G +K+ DFG + + ++ +T G +MAPE + ++K
Sbjct: 119 VIHRDVKPSNVLINALGQVKMCDFGISGYLVD-SVAKTIDAGCKPYMAPERINPELNQKG 177
Query: 869 YGPKVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKLKDPGNLSHKMAMFLN 927
Y K DIWSL PY + TP + L + +P+L S + F +
Sbjct: 178 YSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQL-PADKFSAEFVDFTS 236
Query: 928 WCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKL 965
CL + ++R T +L++ PF T + T +A VKL
Sbjct: 237 QCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKL 274
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 105 bits (261), Expect = 5e-22
Identities = 81/286 (28%), Positives = 129/286 (44%), Gaps = 33/286 (11%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
++ L KIGQG VY A +L T VA+K++ + + + EIL+++ H N+
Sbjct: 147 FEKLDKIGQGTYSSVYKARDLETGKIVAMKKVRFVNMDPESVRFMAREILILRKLDHPNV 206
Query: 756 VNFIDSYLFR--GDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKG 812
+ R G L++V EYME T I +E QI ++ +GL+ H +G
Sbjct: 207 MKLEGLVTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQLFRGLEHCHRRG 266
Query: 813 VIHRDIKSDNILLSMNGDIKLTDFGFC-AQINEVNLKRTTMVGTPYWMAPE-VVSRKEYG 870
++HRDIK N+L++ G +K+ DFG + +L+ T+ V T ++ APE ++ EYG
Sbjct: 267 ILHRDIKGSNLLINNEGVLKIGDFGLANFYRGDGDLQLTSRVVTLWYRAPELLLGATEYG 326
Query: 871 PKVDIWSLXXXXXXXXXXXPPYLNETPL-------------------RALYLIATNGTPK 911
P +D+WS P T + RA +AT+ P
Sbjct: 327 PAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDYWRRATLPLATSFKPS 386
Query: 912 -------LKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFIT 950
+ + M +N L ++PE RG+AA L F T
Sbjct: 387 HPYKPVLAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFFT 432
>7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 396
Score = 105 bits (261), Expect = 5e-22
Identities = 82/290 (28%), Positives = 137/290 (46%), Gaps = 30/290 (10%)
Query: 699 KNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPK-KELIVNEILVMKGSKHNNIVN 757
+ L ++G G G V T+ +A K ++LE +P K+ I+ E+ V+ +IV
Sbjct: 88 EKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFPHIVG 147
Query: 758 FIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSK-GVIH 815
F ++ G++ + MEYM+GGSL ++ + E +G ++ LKGL +L +IH
Sbjct: 148 FYGAFYSDGEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIH 207
Query: 816 RDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDI 875
RD+K NIL++ +G+IK+ DFG Q+ ++ + VGT +M+PE + Y + DI
Sbjct: 208 RDVKPSNILVNSSGEIKICDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYSVQSDI 265
Query: 876 WSLXXXXXXXXXXXPPYL--NETPLRALYL--IATNGTP----------KLKD------P 915
WSL P N L +++ +G P +L D P
Sbjct: 266 WSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEESGQPTDEPRAMAIFELLDYIVNEPP 325
Query: 916 GNLSHKMAM-----FLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLA 960
L HK+ F++ CL P++R LL P+I + E ++
Sbjct: 326 PKLEHKIFSTEFKDFVDICLKKQPDERADLKTLLSHPWIRKAELEEVDIS 375
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 104 bits (260), Expect = 6e-22
Identities = 77/269 (28%), Positives = 126/269 (46%), Gaps = 27/269 (10%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMN--------------------LEKQPKKEL-IVN 742
IG G+ G V A+ L T AIK + + + KE+ V
Sbjct: 131 IGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNKEIRTVR 190
Query: 743 EILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRET 801
E + +H I D Y+ ++V E+++GG + D +++H L E Q R+
Sbjct: 191 EAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQI 250
Query: 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAP 861
L +LH V+HRD+K +NIL+S GDIK+ DFG + + + T G+ Y+ AP
Sbjct: 251 GSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGL-SNLYRRQSRLRTFCGSLYFAAP 309
Query: 862 EVVSRKEY-GPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSH 920
E+++ + Y GP+VD+WS P+ ++ + AL+ GT ++ P LS
Sbjct: 310 ELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPF-DDQNMSALHAKIKKGT--VEYPSYLSS 366
Query: 921 KMAMFLNWCLMVDPEDRGTAADLLEDPFI 949
L+ L+ DP R T ++L P++
Sbjct: 367 DCKGLLSRMLVTDPLKRATLEEVLNHPWM 395
>HsM4885147 [T] KOG0201 Serine/threonine protein kinase
Length = 467
Score = 104 bits (260), Expect = 6e-22
Identities = 83/260 (31%), Positives = 124/260 (46%), Gaps = 14/260 (5%)
Query: 694 PSKL-YKNLIK--IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGS 750
P KL Y+N+ I +GA G VY A ++ T +A K + P + +++ +
Sbjct: 131 PWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLI-----PVDQFKPSDVEIQACF 185
Query: 751 KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLH 809
+H NI + L+ + + ME EGGS+ + + C + E +I V++ LKGL FLH
Sbjct: 186 RHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLH 245
Query: 810 SKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY 869
SK VIH DIK NI+ M+ L DFG Q+ E + GT +M+PEV+ + +
Sbjct: 246 SKKVIHHDIKPSNIVF-MSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGH 304
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLNETPLRA----LYLIATNGTPKLKDPGNLSHKMAMF 925
K DI+SL PP++ P A LY+I P + S M
Sbjct: 305 STKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMREL 364
Query: 926 LNWCLMVDPEDRGTAADLLE 945
+ L +P R AADLL+
Sbjct: 365 IEASLERNPNHRPRAADLLK 384
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 104 bits (260), Expect = 6e-22
Identities = 69/254 (27%), Positives = 124/254 (48%), Gaps = 17/254 (6%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQM---NLEKQPKKELIVNEILVMKGSKHNNIVNFID 760
+G+G G VY A E ++ VA+K + +EK+ + + EI + H NI+ +
Sbjct: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYN 142
Query: 761 SYLFRGDLWVVMEYMEGGSL-TDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+ R +++++EY G L ++ C E + + E L + H K VIHRDIK
Sbjct: 143 YFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIK 202
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
+N+LL + G++K+ DFG+ ++ +L+R TM GT ++ PE++ + + KVD+W +
Sbjct: 203 PENLLLGLKGELKIADFGW--SVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIG 260
Query: 880 XXXXXXXXXXPPY----LNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPE 935
PP+ NET R + + LK P ++ ++ L +P
Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIVKV-------DLKFPASVPTGAQDLISKLLRHNPS 313
Query: 936 DRGTAADLLEDPFI 949
+R A + P++
Sbjct: 314 ERLPLAQVSAHPWV 327
>Hs22035598 [T] KOG0201 Serine/threonine protein kinase
Length = 467
Score = 104 bits (260), Expect = 6e-22
Identities = 83/260 (31%), Positives = 124/260 (46%), Gaps = 14/260 (5%)
Query: 694 PSKL-YKNLIK--IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGS 750
P KL Y+N+ I +GA G VY A ++ T +A K + P + +++ +
Sbjct: 131 PWKLTYRNIGSDFIPRGAFGKVYLAQDIKTKKRMACKLI-----PVDQFKPSDVEIQACF 185
Query: 751 KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLH 809
+H NI + L+ + + ME EGGS+ + + C + E +I V++ LKGL FLH
Sbjct: 186 RHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLH 245
Query: 810 SKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY 869
SK VIH DIK NI+ M+ L DFG Q+ E + GT +M+PEV+ + +
Sbjct: 246 SKKVIHHDIKPSNIVF-MSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGH 304
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLNETPLRA----LYLIATNGTPKLKDPGNLSHKMAMF 925
K DI+SL PP++ P A LY+I P + S M
Sbjct: 305 STKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMREL 364
Query: 926 LNWCLMVDPEDRGTAADLLE 945
+ L +P R AADLL+
Sbjct: 365 IEASLERNPNHRPRAADLLK 384
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 104 bits (260), Expect = 6e-22
Identities = 81/251 (32%), Positives = 123/251 (48%), Gaps = 10/251 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQM---NLEKQPKKELIVNEILVMKGSKHNNIVNFID 760
IG+G V A T +VAIK M + K + I EI +MK +H NIV +
Sbjct: 17 IGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYE 76
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+++V+E++ GG L D + H L E + ++ + + H KGV HRD+K
Sbjct: 77 VLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLK 136
Query: 820 SDNILLSMNGDIKLTDFGFCAQINE-VNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
+N+LL NG++K++DFG A E V L RTT GTP ++APEV+S + Y G DIWS
Sbjct: 137 PENLLLDTNGNLKVSDFGLSALPQEGVELLRTT-CGTPNYVAPEVLSGQGYDGSAADIWS 195
Query: 878 LXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
P+ +ET L LY + P S ++ ++ L +P+ R
Sbjct: 196 CGVILFVILAGYLPF-SETDLPGLY--RKINAAEFSCPPWFSAEVKFLIHRILDPNPKTR 252
Query: 938 GTAADLLEDPF 948
+ +DP+
Sbjct: 253 IQIQGIKKDPW 263
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 104 bits (260), Expect = 6e-22
Identities = 63/179 (35%), Positives = 100/179 (55%), Gaps = 6/179 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNL--EKQPKKELIVNEILVMKGSKHNNIVNFIDS 761
+G+G G VY A + T +VA+K++ L +K+ + EI ++K H +IV ID+
Sbjct: 19 LGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVELIDA 78
Query: 762 YLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+ G L +V EYM+ L V+ + L+ G I + TLKGL + H K V+HRD+K
Sbjct: 79 FPHDGSLHLVFEYMQT-DLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKKWVLHRDMK 137
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-SRKEYGPKVDIWS 877
+N+L+ NG +KL DFG N + T V ++ APE++ ++YG VD+W+
Sbjct: 138 PNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSRQYGAGVDVWA 196
>At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 366
Score = 104 bits (260), Expect = 6e-22
Identities = 77/266 (28%), Positives = 134/266 (49%), Gaps = 15/266 (5%)
Query: 695 SKLYKNLIK---IGQGASGGVYTAYELGTNASVAIKQM--NLEKQPKKELIVNEILVMKG 749
+K Y +L++ IG GA G VY ++ A+K + N E+ +++ I EI +++
Sbjct: 73 AKNYSDLVRGNRIGSGAGGTVYKVIHRPSSRLYALKVIYGNHEETVRRQ-ICREIEILRD 131
Query: 750 SKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLH 809
H N+V + + G++ V++E+M+ GSL + E Q+ +SR+ L GL +LH
Sbjct: 132 VNHPNVVKCHEMFDQNGEIQVLLEFMDKGSLEGAH---VWKEQQLADLSRQILSGLAYLH 188
Query: 810 SKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR--- 866
S+ ++HRDIK N+L++ ++K+ DFG + + + VGT +M+PE ++
Sbjct: 189 SRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLN 248
Query: 867 --KEYGPKVDIWSLXXXXXXXXXXXPPY-LNETPLRALYLIATNGTPKLKDPGNLSHKMA 923
K G DIWSL P+ ++ A + A + + P S +
Sbjct: 249 QGKYDGYAGDIWSLGVSILEFYLGRFPFPVSRQGDWASLMCAICMSQPPEAPATASPEFR 308
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFI 949
F++ CL +P R +A LL+ PFI
Sbjct: 309 HFISCCLQREPGKRRSAMQLLQHPFI 334
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 104 bits (259), Expect = 8e-22
Identities = 75/263 (28%), Positives = 127/263 (47%), Gaps = 18/263 (6%)
Query: 704 IGQGASGGVYTAYELGTNASVAIK--------QMNLEKQPKKELIVNEILVMKGSKHNNI 755
+G+G G VY A E T VA+K Q +EKQ ++E+ + L +H NI
Sbjct: 124 LGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNL-----RHKNI 178
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGA-VSRETLKGLQFLHSKGVI 814
+ + +++++E+ G L + ++ + + L +LH K VI
Sbjct: 179 LRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHVI 238
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
HRDIK +NILL ++G+IKL+DFG+ ++ + +RTT+ GT ++ PE+V KE+ KVD
Sbjct: 239 HRDIKPENILLGIDGEIKLSDFGW--SVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVD 296
Query: 875 IWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDP 934
+WSL PP+ + + A Y LK P + ++ L +P
Sbjct: 297 LWSLGVLTYEFLVGAPPFEDMSGHSATY--KRIAKVDLKIPSFVPPDARDLISRLLQHNP 354
Query: 935 EDRGTAADLLEDPFITEIAEENT 957
E R + ++ P+I + + T
Sbjct: 355 EKRMSLEQVMRHPWIVKYKDSWT 377
>Hs20547878 [R] KOG0589 Serine/threonine protein kinase
Length = 758
Score = 104 bits (259), Expect = 8e-22
Identities = 76/259 (29%), Positives = 115/259 (44%), Gaps = 28/259 (10%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVN 757
Y + IGQGA G Y A + IK++N EK + ++
Sbjct: 4 YDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEK-------------------HQMIP 44
Query: 758 FIDSYLFRGDLWVVMEYMEGGSLTDVVTH---CILTEGQIGAVSRETLKGLQFLHSKGVI 814
F+ G L++VMEY +GG L + + +E QI + GL+ +H + ++
Sbjct: 45 FLTE---NGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKIL 101
Query: 815 HRDIKSDNILLSMNGDI-KLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKV 873
HRDIK+ NI LS NG + KL DFG +N T +GTPY+++PE+ K Y K
Sbjct: 102 HRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKT 161
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVD 933
DIWSL P+ L+ L L PG S ++ ++ V
Sbjct: 162 DIWSLGCVLYELCTLKHPFEGNN-LQQLVLKICQAHFAPISPG-FSRELHSLISQLFQVS 219
Query: 934 PEDRGTAADLLEDPFITEI 952
P DR + +L+ PF+ +
Sbjct: 220 PRDRPSINSILKRPFLENL 238
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 104 bits (259), Expect = 8e-22
Identities = 63/203 (31%), Positives = 108/203 (53%), Gaps = 11/203 (5%)
Query: 701 LIKIGQGASGGVYTAYELGTNASVAIKQMNLE---KQPKKELIVNEILVMKGSKHNNIVN 757
L+ +G G G V+ E A+K M++ ++ +++ + NE V+K H ++
Sbjct: 52 LVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIR 111
Query: 758 FIDSYLFRGDLWVVMEYMEGGSLTDVVT---HCILTEGQIGAVSRETLKGLQFLHSKGVI 814
++ L+++MEY+ GG L + H T G S E + +++LHSK ++
Sbjct: 112 LFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLF--YSAEIICAIEYLHSKEIV 169
Query: 815 HRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVD 874
+RD+K +NILL +G IKLTDFGF ++ + + T+ GTP ++APEV+ K +G VD
Sbjct: 170 YRDLKPENILLDRDGHIKLTDFGFAKKLVD---RTWTLCGTPEYLAPEVIQSKGHGRAVD 226
Query: 875 IWSLXXXXXXXXXXXPPYLNETP 897
W+L PP+ ++ P
Sbjct: 227 WWALGILIFEMLSGFPPFFDDNP 249
>At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 553
Score = 104 bits (259), Expect = 8e-22
Identities = 81/278 (29%), Positives = 132/278 (47%), Gaps = 11/278 (3%)
Query: 687 EICTTG-DPSKLYKNLIKIGQGASGGVYTAYELGTNAS--VAIKQMNLEKQPKKEL--IV 741
EI T G D ++ +KI + + G Y GT S VAIK + E+ + L
Sbjct: 259 EIPTDGTDEWEIDMKQLKIEKKVACGSYGELFRGTYCSQEVAIKILKPERVNAEMLREFS 318
Query: 742 NEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC--ILTEGQIGAVSR 799
E+ +M+ +H N+V FI + +L +V E+M GS+ D + + + V+
Sbjct: 319 QEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIYDFLHKHKGVFKIQSLLKVAL 378
Query: 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWM 859
+ KG+ +LH +IHRD+K+ N+L+ + +K+ DFG A++ + T GT WM
Sbjct: 379 DVSKGMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFG-VARVQTESGVMTAETGTYRWM 437
Query: 860 APEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLS 919
APEV+ K Y + D++S PY TPL+A + G + K P
Sbjct: 438 APEVIEHKPYDHRADVFSYAIVLWELLTGELPYSYLTPLQAAVGVVQKGL-RPKIPKETH 496
Query: 920 HKMAMFLNWCLMVDPEDRGTAADLLE--DPFITEIAEE 955
K+ L C DP R A+++E + I E+ ++
Sbjct: 497 PKLTELLEKCWQQDPALRPNFAEIIEMLNQLIREVGDD 534
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 104 bits (259), Expect = 8e-22
Identities = 80/283 (28%), Positives = 139/283 (48%), Gaps = 9/283 (3%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL---IVNEILVMKGSKHNN 754
YK +G G+ G V A + T VAIK +N K E+ + EI +++ H +
Sbjct: 20 YKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGV 813
I+ + D++VVMEY++ G L D +V L E + ++ + G+++ H V
Sbjct: 80 IIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMV 139
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPK 872
+HRD+K +N+LL +IK+ DFG + + + +T+ G+P + APEV+S K Y GP+
Sbjct: 140 VHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTS-CGSPNYAAPEVISGKLYAGPE 198
Query: 873 VDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMV 932
VD+WS P+ +E + L+ G L P +LS + + L+V
Sbjct: 199 VDVWSCGVILYALLCGTLPFDDEN-IPNLFKKIKGGIYTL--PSHLSSEARDLIPRMLIV 255
Query: 933 DPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKKLAESM 975
DP R T ++ + + +++P + + KK+ E +
Sbjct: 256 DPVKRITIPEIRQHRWFQTHLPRYLAVSPPDTVEQAKKINEEI 298
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 104 bits (259), Expect = 8e-22
Identities = 88/285 (30%), Positives = 137/285 (47%), Gaps = 12/285 (4%)
Query: 696 KLYKNLIK-IGQGASGGVYTAYELGTNASVAIKQMNLEK---QPKKELIVNEILVMKG-S 750
KL+ L K +G+G G Y E T A K ++ +K + KE + EI +M+ S
Sbjct: 70 KLFYTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLS 129
Query: 751 KHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLH 809
NIV F +Y + +VME GG L D ++ +E +V R+ + + H
Sbjct: 130 GQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNICH 189
Query: 810 SKGVIHRDIKSDNILLSMNGD---IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSR 866
GV+HRD+K +N LLS + IK TDFG I E + + +VG+ Y++APEV+ R
Sbjct: 190 FMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGRVYK-DIVGSAYYVAPEVLKR 248
Query: 867 KEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMAMF 925
+ YG ++DIWS PP+ ET I P ++S+
Sbjct: 249 R-YGKEIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAKDL 307
Query: 926 LNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLVKLARMKK 970
+ L DP+ R +AA++L+ P++ E E + L+RMK+
Sbjct: 308 VRRMLTQDPKRRISAAEVLKHPWLREGGEASDKPIDSAVLSRMKQ 352
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 103 bits (258), Expect = 1e-21
Identities = 67/231 (29%), Positives = 116/231 (50%), Gaps = 11/231 (4%)
Query: 737 KELIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIG 795
+ LI NE+ +++ KH NI+ ++ +L++VME ++GG L D +T TE
Sbjct: 256 EHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGS 315
Query: 796 AVSRETLKGLQFLHSKGVIHRDIKSDNILLSMNGD----IKLTDFGFCAQINEVNLKRTT 851
A+ L++LH ++HRDIK +N+L+ D +KL DFG + T
Sbjct: 316 AMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYT 372
Query: 852 MVGTPYWMAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRA-LYLIATNGTP 910
+ GTP ++APE+++ YG KVDIW+ PP+ +E L+ L+ G
Sbjct: 373 VCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKL 432
Query: 911 KLKDP--GNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSL 959
+ P N++ ++ L V+ E R TA +L P++++ A + ++
Sbjct: 433 EFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNM 483
>CE27573 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1420
Score = 103 bits (258), Expect = 1e-21
Identities = 77/259 (29%), Positives = 122/259 (46%), Gaps = 16/259 (6%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFIDSYL 763
I G+ G V+ A ++ ++ +A K M ++++ K I +EI + + H N+V + +
Sbjct: 1131 IASGSFGSVHRAMDIDSHRVIAAKVMRIQRENHKA-IESEINIFRQLIHENLVKYYGVQV 1189
Query: 764 FRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDNI 823
D+ + MEY G+L + + H + + + L+ +Q+LHS +IHRDIK NI
Sbjct: 1190 EDSDVIIFMEYCSQGTL-ERICHGKMDLKMVRQYTNSLLRAVQYLHSHKIIHRDIKPANI 1248
Query: 824 LLSMNGDIKLTDFGFCAQINE---VNLKRTTMVGTPYWMAPEVVSRKE----------YG 870
L +KL DFG +++ E V + T GTP +MAPE+ S E YG
Sbjct: 1249 FLDKCTVLKLGDFGCSSRLVESSTVYGEFQTTAGTPQFMAPEIYSYGEKDETTGSYSGYG 1308
Query: 871 PKVDIWSLXXXXXXXXXXXPPYLNETPLR-ALYLIATNGTPKLKDPGNLSHKMAMFLNWC 929
VDIW+L P+ +T + A L P D + + F + C
Sbjct: 1309 RSVDIWALGATVVNMMTGKVPFEGQTRHQIAFALCFRKQKPTYPDIADKRPDVKRFFDNC 1368
Query: 930 LMVDPEDRGTAADLLEDPF 948
P DR TAA+LL+ F
Sbjct: 1369 FEFLPNDRPTAAELLQTTF 1387
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 103 bits (258), Expect = 1e-21
Identities = 71/227 (31%), Positives = 115/227 (50%), Gaps = 10/227 (4%)
Query: 694 PSKLYKNLIK---IGQGASGGVYTAYELGTNASVAIKQMNL--EKQPKKELIVNEILVMK 748
P K+ +K +GQG G V+ A + +VAIK++ L EK+ + EI ++K
Sbjct: 4 PKKVADRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLK 63
Query: 749 GSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT--HCILTEGQIGAVSRETLKGLQ 806
KH +I+ ID++ + +L +V E+ME L V+ + L+ G + + + LKGL+
Sbjct: 64 ELKHPHIIELIDAFPHKENLHIVFEFMET-DLEAVIRDRNLYLSPGDVKSYLQMILKGLE 122
Query: 807 FLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-S 865
+ H K V+HRD+K +N+L+ NG +KL DFG K T V ++ APE++
Sbjct: 123 YCHGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFG 182
Query: 866 RKEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRAL-YLIATNGTPK 911
K+Y VD+W+ P + + L + A GTPK
Sbjct: 183 AKQYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPK 229
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 103 bits (258), Expect = 1e-21
Identities = 60/179 (33%), Positives = 100/179 (55%), Gaps = 5/179 (2%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN---EILVMKGSKHNNIVNFID 760
+G+G V A + +VAIK ++ EK K ++I EI MK KH N++ +
Sbjct: 37 LGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNVIRMFE 96
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+ ++ V+E++ GG L D ++ + L E + ++ + + + HS+GV HRD+K
Sbjct: 97 VMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLK 156
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY-GPKVDIWS 877
+N+LL NG +K++DFG A + + T GTP ++APEV++ K Y G K D+WS
Sbjct: 157 PENLLLDANGALKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWS 215
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 103 bits (258), Expect = 1e-21
Identities = 72/238 (30%), Positives = 112/238 (46%), Gaps = 7/238 (2%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN---EILVMKGSKHNNIVNFID 760
+G+G G V E T AIK + E +K+ + + E V+K + H +++
Sbjct: 191 LGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKY 250
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTH-CILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
S+ L VM+Y+ GG L ++H I TE + E + L +LHS+G+I+RD+K
Sbjct: 251 SFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLK 310
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
+N+LL +G IK+ DFG C + T GTP ++APEV+ +YG VD W
Sbjct: 311 LENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTG 370
Query: 880 XXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
P+ N LI ++K P N++ + L L DP+ R
Sbjct: 371 VVMYEMICGRLPFYNRDHDVLFTLILVE---EVKFPRNITDEAKNLLAGLLAKDPKKR 425
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 103 bits (258), Expect = 1e-21
Identities = 73/262 (27%), Positives = 120/262 (44%), Gaps = 8/262 (3%)
Query: 694 PSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKE--LIVNEILVMKGSK 751
P Y L +G+G+ G V IK++NL +E E ++ K
Sbjct: 2 PLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLK 61
Query: 752 HNNIVNFIDSYLFR-GDLWVVMEYMEGGSLTDVVTHC---ILTEGQIGAVSRETLKGLQF 807
H NIV + +S+ G L++VM + EGG L + +L E Q+ + LQ+
Sbjct: 62 HPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQY 121
Query: 808 LHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRK 867
LH K ++HRD+K+ N+ L+ IK+ D G + +T++GTPY+M+PE+ S K
Sbjct: 122 LHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNK 181
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLN 927
Y K D+W+L + + +Y I P + P + S ++A +
Sbjct: 182 PYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPAM--PRDYSPELAELIR 239
Query: 928 WCLMVDPEDRGTAADLLEDPFI 949
L PE+R + +L P+I
Sbjct: 240 TMLSKRPEERPSVRSILRQPYI 261
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 103 bits (257), Expect = 1e-21
Identities = 68/240 (28%), Positives = 118/240 (48%), Gaps = 10/240 (4%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLE---KQPKKELIVNEILVMKGSKHNN 754
+ L +G G G V+ E A+K M++ + +++ + NE V+K H
Sbjct: 49 FDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPF 108
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAV-SRETLKGLQFLHSKGV 813
++ ++ L+++MEY+ GG L + + G S E + +++LHSK +
Sbjct: 109 LIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEI 168
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKV 873
++RD+K +NILL +G IKLTDFGF ++ + + T+ GTP ++APEV+ K +G V
Sbjct: 169 VYRDLKPENILLDRDGHIKLTDFGFAKKLVD---RTWTLCGTPEYLAPEVIQSKGHGRAV 225
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVD 933
D W+L PP+ ++ P I K+ P +L + + L+VD
Sbjct: 226 DWWALGILIFEMLSGFPPFFDDNPFGIYQKILAG---KIDFPRHLDFHVKDLIKKLLVVD 282
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 103 bits (257), Expect = 1e-21
Identities = 88/301 (29%), Positives = 137/301 (45%), Gaps = 46/301 (15%)
Query: 698 YKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSKHNNI 755
Y+ L IG+G V A + T VAIK ++ + L + E+ +MK H NI
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115
Query: 756 VNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQI------GAVSRETLK----- 803
V + L+++MEY GG + D +V H + E + G + +T+K
Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSF 175
Query: 804 ------------GLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTT 851
+Q+ H K ++HRD+K++N+LL + +IK+ DFGF + V K T
Sbjct: 176 DLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-VGGKLDT 234
Query: 852 MVGTPYWMAPEVVSRKEY-GPKVDIWSLXXXXXXXXXXXPPY-------LNETPLRALYL 903
G+P + APE+ K+Y GP+VD+WSL P+ L E LR Y
Sbjct: 235 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR 294
Query: 904 IATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAPLV 963
I P +S L L+++P RGT +++D +I EE+ L P V
Sbjct: 295 I----------PFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEED-ELKPFV 343
Query: 964 K 964
+
Sbjct: 344 E 344
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 103 bits (257), Expect = 1e-21
Identities = 72/219 (32%), Positives = 107/219 (47%), Gaps = 30/219 (13%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMN-----LEKQPKKELIVNEILVMKGSKHNNIVNF 758
+ GA G VY T A+K+MN L Q + +IL M + +V+F
Sbjct: 364 VSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNPF--VVSF 421
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
S+ R L ++MEY+EGG ++ L + ET+ +++LHS G++HRD
Sbjct: 422 YGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSYGIVHRD 481
Query: 818 IKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMV-------------------GTPYW 858
+K DN+L++ G IKLTDFG ++I +N RTT+V GTP +
Sbjct: 482 LKPDNLLITAMGHIKLTDFGL-SKIGLMN--RTTLVAEGYDAVVETQQFQDKQLCGTPEY 538
Query: 859 MAPEVVSRKEYGPKVDIWSLXXXXXXXXXXXPPYLNETP 897
+APEV+ R+ YG VD W+L P+ ETP
Sbjct: 539 IAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETP 577
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 103 bits (257), Expect = 1e-21
Identities = 86/263 (32%), Positives = 124/263 (46%), Gaps = 11/263 (4%)
Query: 696 KLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN---EILVMKG-SK 751
KLY ++G+G G YT E T + A K + K +K+ I + EI +M+ S
Sbjct: 100 KLYTLGKELGRGQFGITYTCKENSTGNTYACKSILKRKLTRKQDIDDVKREIQIMQYLSG 159
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHS 810
NIV +Y R + +VME G L D ++ +E V R L +Q H
Sbjct: 160 QENIVEIKGAYEDRQSIHLVMELCGGSELFDRIIAQGHYSEKAAAGVIRSVLNVVQICHF 219
Query: 811 KGVIHRDIKSDNILLSM---NGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRK 867
GVIHRD+K +N LL+ N +K TDFG I E + R +VG+ Y++APEV+ R+
Sbjct: 220 MGVIHRDLKPENFLLASTDENAMLKATDFGLSVFIEEGKVYR-DIVGSAYYVAPEVL-RR 277
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP-GNLSHKMAMFL 926
YG ++DIWS PP+ +ET I P ++S +
Sbjct: 278 SYGKEIDIWSAGIILYILLCGVPPFWSETEKGIFNEIIKGEIDFDSQPWPSISESAKDLV 337
Query: 927 NWCLMVDPEDRGTAADLLEDPFI 949
L DP+ R +AA LE P+I
Sbjct: 338 RKLLTKDPKQRISAAQALEHPWI 360
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 103 bits (257), Expect = 1e-21
Identities = 118/478 (24%), Positives = 189/478 (38%), Gaps = 80/478 (16%)
Query: 443 MKEQQQHPQAVMDIVKFYQDVTENSGEEKVF----KTFKVGGGS--GANIASTPSFRTPS 496
+K++ + +A+ +I++ Q+ NS + V G + A+ S P TP+
Sbjct: 559 VKDRHKRQKALKEIIE-RQEENSNSNSNGALTINDNSSSVDGNTPNAADGRSAPGSGTPA 617
Query: 497 TAS----------------VQKFETPQMQTDATFPN--ENNDTPYS-SNLQGPLLTNDFS 537
AS + P Q D+ N N D P S + L+ PLL FS
Sbjct: 618 AASTTSNGLQALGSKPDLDLNNIPMPNKQNDSVVSNPASNADVPDSVAQLKQPLLVPPFS 677
Query: 538 ETVNNEKFIPTRPAPKPQGSSTVSRR-VEIPSPINSLGHGTPKVQRSDTQSSSIFSFKKM 596
+ NN K P P G + + PSP V S + + S+ +
Sbjct: 678 ASKNNIKPKSLTSLPLPPGMNVLDLAGARSPSPGQKKESDEKNVTSSGSANKSVLNL--- 734
Query: 597 PTLKSEQPLPP-IPKAAEKXXXXXXXXXXXXXXXXXXXXXXEQSSIPAIPSGLAVEVKEE 655
P+PP IP + E P V +
Sbjct: 735 -------PMPPVIPGSEELSGDDDVIDSPEDFDAPAVGTVHGHGGGPGTTRQRPVILNRR 787
Query: 656 SNTSNVXXXXXXXXXXXXXXXXXXXXXSKLTEICTTGDPSKLYKNLIKIGQGASGGVYTA 715
+ +NV E C +++ + +IG+G G VY A
Sbjct: 788 DSRNNVRDWG---------------------ERCVD-----VFEMIAQIGEGTYGQVYKA 821
Query: 716 YELGTNASVAIKQMNLEKQPKKELI--VNEILVMKGSKHNNIVNFI-------DSYLFR- 765
+ TN VA+K++ LE + + I V EI +++ H NIVN D+ FR
Sbjct: 822 RDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRK 881
Query: 766 --GDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSDN 822
G ++V EYM+ + + + + E ++ ++ L GL + H K +HRDIK N
Sbjct: 882 DKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSN 941
Query: 823 ILLSMNGDIKLTDFGFCAQINEVNLKR--TTMVGTPYWMAPEVVSRKE-YGPKVDIWS 877
IL++ G +KL DFG N + +R T V T ++ PE++ +E YGP +D+WS
Sbjct: 942 ILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWS 999
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 103 bits (257), Expect = 1e-21
Identities = 76/268 (28%), Positives = 126/268 (46%), Gaps = 21/268 (7%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNL-------EKQPKK--ELIVNEILVMKGSK-HN 753
+G+G S V E T A K ++L E P E EI +++ H
Sbjct: 29 LGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMGHP 88
Query: 754 NIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHCI-LTEGQIGAVSRETLKGLQFLHSKG 812
I++ D + +++V E G L D +T + L+E + + R+ +G++++H+K
Sbjct: 89 YIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKS 148
Query: 813 VIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV------SR 866
++HRD+K +NILL N ++K+TDFGF Q+ E K T + GTP ++APE +
Sbjct: 149 IVHRDLKPENILLDENHNVKITDFGFAKQLQE-GEKLTNLCGTPGYLAPETLKCNMFEGS 207
Query: 867 KEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDP--GNLSHKMAM 924
Y +VDIW+ PP+ + + L I G P ++S
Sbjct: 208 PGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNI-MEGKYSFTSPEWADISEDPKD 266
Query: 925 FLNWCLMVDPEDRGTAADLLEDPFITEI 952
+ CL+VDP R T ++L PF ++
Sbjct: 267 LIRKCLVVDPSQRITVKEVLRHPFFNQM 294
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 103 bits (256), Expect = 2e-21
Identities = 71/238 (29%), Positives = 116/238 (47%), Gaps = 16/238 (6%)
Query: 740 IVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDV-VTHCILTEGQIGAVS 798
I EI++MK H N+++ D + +L++++EY E G L ++ V H L E +
Sbjct: 74 IEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCF 133
Query: 799 RETLKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYW 858
R+ + G+ + H+ G++HRD+K +N+LL +IK+ DFG A + +L T+ G+P++
Sbjct: 134 RQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETS-CGSPHY 192
Query: 859 MAPEVVSRKEY-GPKVDIWSLXXXXXXXXXXXPPYLNET-PLRALYLIATNGTPKLKDPG 916
APE+VS Y G D+WS P+ E +R L L G ++ +
Sbjct: 193 AAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDT 252
Query: 917 NLSHKMAMFLNWCLMVDPEDRGTAADLLEDPF------------ITEIAEENTSLAPL 962
+S + L+VDP R D+L P I ++ ENT L PL
Sbjct: 253 EISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPL 310
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 103 bits (256), Expect = 2e-21
Identities = 63/252 (25%), Positives = 126/252 (50%), Gaps = 7/252 (2%)
Query: 704 IGQGASGGVYTAYELGTN---ASVAIKQMNLEKQPKKELIVNEILVMKGSKHNNIVNFID 760
+G+G Y +L N A+ I + K ++E I EI + + H ++V F
Sbjct: 88 LGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYH 147
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVV-THCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
+ + ++++++EY S+ ++ +LTE ++ R+ + GL++LH + ++HRD+K
Sbjct: 148 YFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLK 207
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
N ++ ++K+ DFG A++ + +R T+ GTP +++PEV++++ +G + DIW+L
Sbjct: 208 LGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALG 267
Query: 880 XXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDRGT 939
PP+ T L+ Y + P +L + L +PEDR +
Sbjct: 268 CVMYTMLLGRPPF-ETTNLKETYRCIREA--RYTMPSSLLAPAKHLIASMLSKNPEDRPS 324
Query: 940 AADLLEDPFITE 951
D++ F +
Sbjct: 325 LDDIIRHDFFLQ 336
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 103 bits (256), Expect = 2e-21
Identities = 75/258 (29%), Positives = 117/258 (45%), Gaps = 12/258 (4%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELI---VNEILVMKGSKHNNIVNFID 760
+G+G G V E T A+K + E K+ + V E V++ ++H +
Sbjct: 158 LGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKY 217
Query: 761 SYLFRGDLWVVMEYMEGGSLT-DVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIK 819
++ L VMEY GG L + + TE + E + L++LHS+ V++RDIK
Sbjct: 218 AFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIK 277
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
+N++L +G IK+TDFG C + T GTP ++APEV+ +YG VD W L
Sbjct: 278 LENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLG 337
Query: 880 XXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR-- 937
P+ N+ R LI +++ P LS + L L DP+ R
Sbjct: 338 VVMYEMMCGRLPFYNQDHERLFELILME---EIRFPRTLSPEAKSLLAGLLKKDPKQRLG 394
Query: 938 ---GTAADLLEDPFITEI 952
A +++E F I
Sbjct: 395 GGPSDAKEVMEHRFFLSI 412
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 103 bits (256), Expect = 2e-21
Identities = 78/270 (28%), Positives = 133/270 (48%), Gaps = 11/270 (4%)
Query: 694 PSKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKEL--IVNEILVMKGSK 751
P KL K L G+G +G V T T VAIK +N EK + L + EI +MK +
Sbjct: 46 PYKLEKTL---GKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIE 102
Query: 752 HNNIVNFIDSYLFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHS 810
H ++++ D Y + L++++E++ GG L D +V L + R+ + L F H+
Sbjct: 103 HPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHA 162
Query: 811 KGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEY- 869
+ HRD+K +N+LL +IK+ DFG + E ++ T+ G+P++ PEV+ ++Y
Sbjct: 163 HNICHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETS-CGSPHYACPEVIRGEKYD 221
Query: 870 GPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWC 929
G K D+WS P+ ++ LR L G + P + + L
Sbjct: 222 GRKADVWSCGVILYALLVGALPF-DDDNLRNLLEKVKRGVFHI--PHFVPADVQSLLRAM 278
Query: 930 LMVDPEDRGTAADLLEDPFITEIAEENTSL 959
+ VDP R + AD+ + P+++ + + L
Sbjct: 279 IEVDPGKRYSLADVFKHPWVSGTTKADPEL 308
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 103 bits (256), Expect = 2e-21
Identities = 81/265 (30%), Positives = 122/265 (45%), Gaps = 21/265 (7%)
Query: 704 IGQGASGGVYTA-YELGTNASVAIKQMNLEKQPK-KELIVNEILVMK---GSKHNNIVNF 758
+G GA VY Y T+ VAIK + + K K L+ EI ++K KH N+V
Sbjct: 15 LGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSLKHENLVGL 74
Query: 759 IDSYLFRGDLWVVMEYMEGGSLTDVVTH-CILTEGQIGAVSRETLKGLQFLHSKGVIHRD 817
+ +++VME+ GG L D + L E I + L+ ++ KG++HRD
Sbjct: 75 LKCTETPTHVYLVMEFCNGGDLADYLQQKTTLNEDTIQHFVVQIAHALEAINKKGIVHRD 134
Query: 818 IKSDNILLSMNGD----------IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRK 867
+K NILL N IKL DFGF +N+ + T+ G+P +MAPEV+
Sbjct: 135 LKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFLND-GVMAATLCGSPMYMAPEVIMSM 193
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETP--LRALYLIATNGTPKLKDPGNLSHKMAMF 925
+Y K D+WS+ P++ +TP L+A Y P + P S +
Sbjct: 194 QYDAKADLWSIGTILFQCLTGKAPFVAQTPPQLKAYYEKTRELRPNI--PEWCSPNLRDL 251
Query: 926 LNWCLMVDPEDRGTAADLLEDPFIT 950
L L + +DR + D PF+T
Sbjct: 252 LLRLLKRNAKDRISFEDFFNHPFLT 276
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 103 bits (256), Expect = 2e-21
Identities = 72/238 (30%), Positives = 116/238 (48%), Gaps = 9/238 (3%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQPKK---ELIVNEILVMKGSKHNNIVNFID 760
+GQGA G VY + T+ A+K M +K +K E + E ++ H IV
Sbjct: 146 VGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIVQLKY 205
Query: 761 SYLFRGDLWVVMEYMEGGSLTDVVTHCILTEGQIGAV-SRETLKGLQFLHSKGVIHRDIK 819
S+ + L++V++++ GG L + H L + V + E + + LH KG++HRD+K
Sbjct: 206 SFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLK 265
Query: 820 SDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLX 879
+NIL+ ++G + LTDFG + E N + +M GT +MAPE+V K + D WS+
Sbjct: 266 PENILMDVDGHVMLTDFGLAKEFEE-NTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVG 324
Query: 880 XXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
PP+L ++ K+K P LS++ L L +PE R
Sbjct: 325 ILLYEMLTGKPPFLGSKGKIQQKIV----KDKIKLPQFLSNEAHALLKGLLQKEPERR 378
>Hs4506889 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kinase MKK4
Length = 399
Score = 102 bits (255), Expect = 2e-21
Identities = 81/277 (29%), Positives = 129/277 (46%), Gaps = 16/277 (5%)
Query: 699 KNLIKIGQGASGGVYTAYELGTNASVAIKQMN--LEKQPKKELIVNEILVMKGSKHNNIV 756
K+L +IG+GA G V + +A+K++ ++++ +K+L+++ +VM+ S IV
Sbjct: 103 KDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIV 162
Query: 757 NFIDSYLFRGDLWVVMEYMEGG-----SLTDVVTHCILTEGQIGAVSRETLKGLQFLHSK 811
F + GD W+ ME M V ++ E +G ++ T+K L L
Sbjct: 163 QFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKEN 222
Query: 812 -GVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV----SR 866
+IHRDIK NILL +G+IKL DFG Q+ + ++ +T G +MAPE + SR
Sbjct: 223 LKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD-SIAKTRDAGCRPYMAPERIDPSASR 281
Query: 867 KEYGPKVDIWSLXXXXXXXXXXXPPYLN-ETPLRALYLIATNGTPKL--KDPGNLSHKMA 923
+ Y + D+WSL PY + L + P+L + S
Sbjct: 282 QGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFI 341
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLA 960
F+N CL D R +LL+ PFI E +A
Sbjct: 342 NFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVA 378
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 102 bits (255), Expect = 2e-21
Identities = 68/224 (30%), Positives = 115/224 (50%), Gaps = 8/224 (3%)
Query: 695 SKLYKNLIKIGQGASGGVYTAYELGTNASVAIKQMNLEKQPKKELIVN-----EILVMKG 749
+K Y+ L +G+G VY A + TN VAIK++ L + + + +N EI +++
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQE 68
Query: 750 SKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTHC-ILTEGQIGAVSRETLKGLQFL 808
H NI+ +D++ + ++ +V ++ME + + +LT I A TL+GL++L
Sbjct: 69 LSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYL 128
Query: 809 HSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-SRK 867
H ++HRD+K +N+LL NG +KL DFG N T V T ++ APE++ +
Sbjct: 129 HQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGAR 188
Query: 868 EYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRAL-YLIATNGTP 910
YG VD+W++ P ++ L L + T GTP
Sbjct: 189 MYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTP 232
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 102 bits (254), Expect = 3e-21
Identities = 74/256 (28%), Positives = 117/256 (44%), Gaps = 18/256 (7%)
Query: 703 KIGQGASGGVYTAYELGTNASVAIKQM--------NLEKQPKKELIVNEILVMKGSKHNN 754
K+G+G G VY T A+K M NL+KQ ++E+ + L H N
Sbjct: 109 KLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSL-----NHPN 163
Query: 755 IVNFIDSYLFRGDLWVVMEYMEGGSLTDVVT-HCILTEGQIGAVSRETLKGLQFLHSKGV 813
+ + ++++MEY+ G + ++ H + + L ++H K +
Sbjct: 164 LTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNI 223
Query: 814 IHRDIKSDNILLSMNGDIKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVVSRKEYGPKV 873
IHRDIK +NIL+ N IKLTDFG+ + IN +R T+ GT +++PE+V +EY +
Sbjct: 224 IHRDIKPENILIGFNNVIKLTDFGW-SIINPPENRRKTVCGTIDYLSPEMVESREYDHTI 282
Query: 874 DIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGTPKLKDPGNLSHKMAMFLNWCLMVD 933
D W+L PP+ E IA +K P N+S + L D
Sbjct: 283 DAWALGVLAFELLTGAPPFEEEMKDTTYKRIA---ALDIKMPSNISQDAQDLILKLLKYD 339
Query: 934 PEDRGTAADLLEDPFI 949
P+DR D+ P+I
Sbjct: 340 PKDRMRLGDVKMHPWI 355
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 102 bits (254), Expect = 3e-21
Identities = 82/266 (30%), Positives = 124/266 (45%), Gaps = 23/266 (8%)
Query: 704 IGQGASGGVYTAYELGTNASVAIKQMNLEKQ-PKKELIVNEILVMKGSKHNNIVNFIDSY 762
+GQGA V A E T + A+K ++ K + + E+ V++ H IV Y
Sbjct: 204 VGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFY 263
Query: 763 LFRGDLWVVMEYMEGGSLTD-VVTHCILTEGQIGAVSRETLKGLQFLHSKGVIHRDIKSD 821
++VME++ GG L D V H + E +SR+ L ++++HS G+ HRD+K D
Sbjct: 264 EDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPD 323
Query: 822 NILLSMNGD--IKLTDFGFCAQINEVNLKRTTMVGTPYWMAPEVV-------------SR 866
NIL+ + +K+TDFG A++ T GT ++APEV+ R
Sbjct: 324 NILIEQDDPVLVKITDFGL-AKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEER 382
Query: 867 KEYGPKVDIWSLXXXXXXXXXXXPPYLNETPLRALYLIATNGT---PKLKDPGNLSHKMA 923
EY VD+WS+ P+ T LY G+ LKD +S +
Sbjct: 383 NEYSSLVDMWSMGCLVYVILTGHLPFSGSTQ-DQLYKQIGRGSYHEGPLKD-FRISEEAR 440
Query: 924 MFLNWCLMVDPEDRGTAADLLEDPFI 949
F++ L VDP +R TAA L P+I
Sbjct: 441 DFIDSLLQVDPNNRSTAAKALNHPWI 466
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.309 0.128 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,497,714
Number of Sequences: 60738
Number of extensions: 2242187
Number of successful extensions: 10834
Number of sequences better than 1.0e-05: 1636
Number of HSP's better than 0.0 without gapping: 415
Number of HSP's successfully gapped in prelim test: 1221
Number of HSP's that attempted gapping in prelim test: 7292
Number of HSP's gapped (non-prelim): 2065
length of query: 989
length of database: 30,389,216
effective HSP length: 116
effective length of query: 873
effective length of database: 23,343,608
effective search space: 20378969784
effective search space used: 20378969784
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)