ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactII3501   normal        K     KOG1318  Transcription                                                  Helix loop helix transcription factor EB

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactII3501 1204147  1205223 359  
         (359 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YJR060w [K] KOG1318 Helix loop helix transcription factor EB          147   2e-35
SPAC3F10.12c [K] KOG1318 Helix loop helix transcription factor EB      79   8e-15
Hs6005934 [K] KOG1318 Helix loop helix transcription factor EB         53   8e-07
Hs4507847 [K] KOG1318 Helix loop helix transcription factor EB         51   3e-06
Hs18580565 [K] KOG1318 Helix loop helix transcription factor EB        51   3e-06

>YJR060w [K] KOG1318 Helix loop helix transcription factor EB
          Length = 351

 Score =  147 bits (372), Expect = 2e-35
 Identities = 82/151 (54%), Positives = 97/151 (63%), Gaps = 1/151 (0%)

Query: 204 DREDGSQPDGTEHDDEENXXXXXXXXXXXXXXXXXTETGST-AWKQQRKESHKEVERRRR 262
           DR    Q D  ++DD +                  T   +T  WK+QRK+SHKEVERRRR
Sbjct: 176 DRGPEHQQDDEDNDDADIDLKKDISMQPGRRGRKPTTLATTDEWKKQRKDSHKEVERRRR 235

Query: 263 QNINTAIEKLSDLLPVKETSKAAILSRAAEYIQKMKETETANIEKWTLQKLLGEQQVSSL 322
           +NINTAI  LSDLLPV+E+SKAAIL+ AAEYIQK+KET+ ANIEKWTLQKLL EQ  S L
Sbjct: 236 ENINTAINVLSDLLPVRESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQL 295

Query: 323 TSANDKLEQELSKAYKNXXXXXXXXXXAGIE 353
            SAN+KL++EL  AYK            GIE
Sbjct: 296 ASANEKLQEELGNAYKEIEYMKRVLRKEGIE 326


>SPAC3F10.12c [K] KOG1318 Helix loop helix transcription factor EB
          Length = 201

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 38/98 (38%), Positives = 64/98 (64%)

Query: 242 GSTAWKQQRKESHKEVERRRRQNINTAIEKLSDLLPVKETSKAAILSRAAEYIQKMKETE 301
           GS  W + ++ SHKEVERRRR+ I+  I++L++++P  E +K +IL R A+YI+ +KE E
Sbjct: 81  GSEEWYKAKRLSHKEVERRRREAISEGIKELANIVPGCEKNKGSILQRTAQYIRSLKEME 140

Query: 302 TANIEKWTLQKLLGEQQVSSLTSANDKLEQELSKAYKN 339
               EK  L+KL+ +  +  L   N +L+ E  +A+++
Sbjct: 141 EMCREKSNLEKLVADHTIQELARENARLKSECERAWRS 178


>Hs6005934 [K] KOG1318 Helix loop helix transcription factor EB
          Length = 310

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 36/108 (33%), Positives = 58/108 (53%), Gaps = 13/108 (12%)

Query: 239 TETGSTAWKQQRKESHKEVERRRRQNINTAIEKLSDLLP---VKET----SKAAILSRAA 291
           +E   T   ++R+  H EVERRRR  IN  I +LS ++P   ++ T    SK  ILS+A 
Sbjct: 189 SEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKAC 248

Query: 292 EYIQKMKET------ETANIEKWTLQKLLGEQQVSSLTSANDKLEQEL 333
           +YIQ+++++      E   +++  L   +  QQV  L + N  L  +L
Sbjct: 249 DYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQL 296


>Hs4507847 [K] KOG1318 Helix loop helix transcription factor EB
          Length = 346

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 32/101 (31%), Positives = 51/101 (49%), Gaps = 13/101 (12%)

Query: 248 QQRKESHKEVERRRRQNINTAIEKLSDLLP-------VKETSKAAILSRAAEYIQKMKET 300
           ++R+  H EVERRRR  IN  I +LS ++P           SK  ILS+A +YI+++++T
Sbjct: 234 ERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQT 293

Query: 301 ET------ANIEKWTLQKLLGEQQVSSLTSANDKLEQELSK 335
                      E+  +   L  QQ+  L + N  L  +L +
Sbjct: 294 NQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQ 334


>Hs18580565 [K] KOG1318 Helix loop helix transcription factor EB
          Length = 279

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 32/101 (31%), Positives = 51/101 (49%), Gaps = 13/101 (12%)

Query: 248 QQRKESHKEVERRRRQNINTAIEKLSDLLP-------VKETSKAAILSRAAEYIQKMKET 300
           ++R+  H EVERRRR  IN  I +LS ++P           SK  ILS+A +YI+++++T
Sbjct: 167 ERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQT 226

Query: 301 ET------ANIEKWTLQKLLGEQQVSSLTSANDKLEQELSK 335
                      E+  +   L  QQ+  L + N  L  +L +
Sbjct: 227 NQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQ 267


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.299    0.121    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,949,278
Number of Sequences: 60738
Number of extensions: 738761
Number of successful extensions: 5880
Number of sequences better than 1.0e-05: 5
Number of HSP's better than  0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5875
Number of HSP's gapped (non-prelim): 5
length of query: 359
length of database: 30,389,216
effective HSP length: 108
effective length of query: 251
effective length of database: 23,829,512
effective search space: 5981207512
effective search space used: 5981207512
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)