ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3579 good L KOG0891 Replication, recombination and repair DNA-dependent protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3579 1222276 1229625 2450
(2450 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL203c [L] KOG0891 DNA-dependent protein kinase 3495 0.0
YJR066w [L] KOG0891 DNA-dependent protein kinase 3261 0.0
SPBC216.07c [L] KOG0891 DNA-dependent protein kinase 2150 0.0
SPBC30D10.10c [L] KOG0891 DNA-dependent protein kinase 2066 0.0
Hs4826730 [L] KOG0891 DNA-dependent protein kinase 1736 0.0
7297995 [L] KOG0891 DNA-dependent protein kinase 1646 0.0
At1g50030 [L] KOG0891 DNA-dependent protein kinase 1520 0.0
CE28813 [L] KOG0891 DNA-dependent protein kinase 608 e-173
CE07705 [L] KOG0891 DNA-dependent protein kinase 608 e-173
Hs18765739 [L] KOG0891 DNA-dependent protein kinase 223 3e-57
Hs14719394 [L] KOG0891 DNA-dependent protein kinase 223 3e-57
CE27869 [L] KOG0891 DNA-dependent protein kinase 215 8e-55
Hs20336203 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in te... 203 2e-51
Hs20336199 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in te... 203 2e-51
At3g48190 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in tel... 198 8e-50
Hs4502325 [TBLD] KOG0890 Protein kinase of the PI-3 kinase famil... 196 3e-49
Hs22041606 [TBLD] KOG0890 Protein kinase of the PI-3 kinase fami... 196 3e-49
7293222 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family ... 196 4e-49
7290761 [L] KOG0891 DNA-dependent protein kinase 189 4e-47
SPBC216.05 [TBLD] KOG0890 Protein kinase of the PI-3 kinase fami... 189 5e-47
7299977 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telom... 184 2e-45
YBL088c [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telom... 175 9e-43
At5g40820 [TBLD] KOG0890 Protein kinase of the PI-3 kinase famil... 174 1e-42
SPCC23B6.03c [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in ... 166 6e-40
YBR136w [TBLD] KOG0890 Protein kinase of the PI-3 kinase family ... 162 8e-39
ECU02g1130 [TBLD] KOG0890 Protein kinase of the PI-3 kinase fami... 140 3e-32
Hs13654237 [L] KOG0891 DNA-dependent protein kinase 137 3e-31
CE22176 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telom... 108 1e-22
CE28250 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family ... 99 7e-20
CE25103 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family ... 99 7e-20
At2g17930 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TR... 91 2e-17
Hs4507691 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TR... 88 2e-16
YHR099w [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1... 82 1e-14
SPAC1F5.11c [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/... 74 2e-12
Hs19923289 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic s... 69 1e-10
SPAC458.05 [TU] KOG0906 Phosphatidylinositol 3-kinase VPS34 invo... 65 1e-09
7302249 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1... 65 1e-09
Hs5453894 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic su... 61 2e-08
Hs5453892 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic su... 60 4e-08
At5g64070 [TU] KOG0903 Phosphatidylinositol 4-kinase involved in... 60 6e-08
7290340 [T] KOG0902 Phosphatidylinositol 4-kinase 59 7e-08
CE23035 [T] KOG0902 Phosphatidylinositol 4-kinase 57 4e-07
CE23506 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic subu... 54 2e-06
>YKL203c [L] KOG0891 DNA-dependent protein kinase
Length = 2473
Score = 3495 bits (9063), Expect = 0.0
Identities = 1730/2462 (70%), Positives = 2062/2462 (83%), Gaps = 18/2462 (0%)
Query: 2 LRRKGES---AKKRLVSGTAASLQELSLKPNSNGIQSSGKTEDTDVPGDSISGEFGA-AL 57
LR++ E +K+L + + E+S N++ + + G + G G +
Sbjct: 17 LRQRAEGKHRTRKKLTHKSHSHDDEMSTTSNTDSNHNGPNDSGRVITGSA--GHIGKISF 74
Query: 58 SDSNVENSVKAFNLIFTKLKSTSEMERTAASFELRSSLISLAREVSTEHFQRFSNDINNK 117
DS ++ + NLIF KLKS ER + + EL ++L SLAREVS E FQRFSN +NNK
Sbjct: 75 VDSELDTTFSTLNLIFDKLKSDVPQERASGANELSTTLTSLAREVSAEQFQRFSNSLNNK 134
Query: 118 VFELIHGNDSNEKLGGVLAVDTLIDFYSRTDELPNQTSRLANYLRVLIPSNDIEVMRAAA 177
+FELIHG S+EK+GG+LAVDTLI FY T+ELPNQTSRLANYLRVLIPS+DIEVMR AA
Sbjct: 135 IFELIHGFTSSEKIGGILAVDTLISFYLSTEELPNQTSRLANYLRVLIPSSDIEVMRLAA 194
Query: 178 GTLGKLAVPGGTLTSEFVEFEVKTCIEWLTTSPENSSSNSKQEYRKHASLLIISAIADNS 237
TLG+L VPGGTLTS+FVEFEV+TCI+WLT + +N+SS+SK EYR+HA+LLII A+ADNS
Sbjct: 195 NTLGRLTVPGGTLTSDFVEFEVRTCIDWLTLTADNNSSSSKLEYRRHAALLIIKALADNS 254
Query: 238 PYLLYPFVNSILDNIWRALRDTKLVIRTDASVTLGKCLTIINNRDSSLTKKWVQRLFNGC 297
PYLLYP+VNSILDNIW LRD KL+IR DA+V LGKCLTII +RD +L K+W QRLF GC
Sbjct: 255 PYLLYPYVNSILDNIWVPLRDAKLIIRLDAAVALGKCLTIIQDRDPALGKQWFQRLFQGC 314
Query: 298 IYGLQLNSTVSIHGTLLVYRQLVSLEGGYLKDKFEEIYETTMRYRENKNIIIRKEIYAII 357
+GL LN+ S+H TLLV+R+L+SL+ YL+DK+++IY++TM+Y+E K +IR+E+YAI+
Sbjct: 315 THGLSLNTNDSVHATLLVFRELLSLKAPYLRDKYDDIYKSTMKYKEYKFDVIRREVYAIL 374
Query: 358 PVLAAFDPKLFTQKYLDSTMIHYLTLLKNMNSHPVTNSDKGPILISVGDIAYYVGPDIGP 417
P+LAAFDP +FT+KYLD M+HYL LKN++ + NSDK IL+S+GDIA+ VG I P
Sbjct: 375 PLLAAFDPAIFTKKYLDRIMVHYLRYLKNIDMNAANNSDKPFILVSIGDIAFEVGSSISP 434
Query: 418 YLDAIVENLRDGLTTKYKFRKDYEQEIFYCIGKLACAVRPLLAKYLNRGLLEYMLACPLS 477
Y+ I++N+R+GL TK+K RK +E+++FYCIGKLACA+ P AK+LN+ LL ML CP+S
Sbjct: 435 YMTLILDNIREGLRTKFKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMS 494
Query: 478 DHMQETLLIVCEKIPSLEGTINEKLLNIICLVLSGEKFRPPGSPTPMKPFSAETARNYRD 537
DHMQETL+I+ EKIPSLE T+N ++LN++ + LSGEKF FS E AR R+
Sbjct: 495 DHMQETLMILNEKIPSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRN 554
Query: 538 QSLFKKTGEANNDIFDAVILTKALRMLSDIKPKYSLTEFIRRVIISYMEHDNLQVRKLAA 597
QS KKTGE+N+DI DA IL + +ML I +YSLTEF+R + ISY+EH++ VRKLAA
Sbjct: 555 QSFMKKTGESNDDITDAQILIQCFKMLQLIHHQYSLTEFVRLITISYIEHEDSSVRKLAA 614
Query: 598 LTSCDLFVEDSICKQTSLYALNVVSEVLSKLLTVAITDPVAEIRLEILRHLDTNFDPQLS 657
LTSCDLF++D ICKQTS++AL+ VSEVLSKLL +AITDPVAEIRLEIL+HL +NFDPQL+
Sbjct: 615 LTSCDLFIKDDICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLA 674
Query: 658 QPDNTKLLFMALNDEVFAIQMEAMRICGRLALVNPAYVIPSLRKTLIQLLTELKHSKLTR 717
QPDN +LLFMALNDE+F IQ+EA++I GRL+ VNPAYV+PSLRKTL++LLT+LK S + +
Sbjct: 675 QPDNLRLLFMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPK 734
Query: 718 KKEECASLLCTLISSSSDVTKPYLEPVIEILLPKSQDSSSAVASTALKAIGELSVVGGED 777
KKEE A+LLCTLI+SS +V KPY++P+++++LPK QD+SSAVASTALK +GELSVVGG++
Sbjct: 735 KKEESATLLCTLINSSDEVAKPYIDPILDVILPKCQDASSAVASTALKVLGELSVVGGKE 794
Query: 778 MVPFLDELMPLIIDTFQDQSNSFKRNAALKALGQLSASSGYVIDPLLDYPELLGVLLNIL 837
M +L ELMPLII+TFQDQSNSFKR+AAL LGQL+ASSGYV+ PLLDYPELLG+L+NIL
Sbjct: 795 MTRYLKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINIL 854
Query: 838 KSESSQNIRRETVRLIGILGALDPYKHREVERTSSTNITVEQNAPPIDVALLMQGMSPSN 897
K+E++ +IRR TVRLIGILGALDPYKHRE+E TS++ +VEQNAP ID+ALLMQG+SPSN
Sbjct: 855 KTENNPHIRRGTVRLIGILGALDPYKHREIEVTSNSKSSVEQNAPSIDIALLMQGVSPSN 914
Query: 898 EEYYPTVVIGVLMKILKDPSLSIHHSTVIQAIMHIFQTMGLRCVIFLKQIIPGFILVMHT 957
+EYYPTVVI LMKIL DPSLSIHH+ IQAIMHIFQ +GLRCV FL QIIPG ILVM +
Sbjct: 915 DEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGIILVMRS 974
Query: 958 CPPSLLELYFQQLSVLISIVKQHIRLHVSEIVEVISEFFPIVKLQLTIISVIESLSRALE 1017
CPPS L+ YFQQL LISIVKQHIR HV +I VI EFFPI+KLQ+TIISVIES+S+ALE
Sbjct: 975 CPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPIIKLQITIISVIESISKALE 1034
Query: 1018 GEFNPYLPNILSLFLDVLEKDQSNKKVVSIRILKSLVVFGPHLEEYAHLVLPTIIKLSEF 1077
GEF ++P L+ FLD+LE DQSNK++V IRILKSLV FGP+LE+Y+HL++P +++++E+
Sbjct: 1035 GEFKRFVPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIVVRMTEY 1094
Query: 1078 SSGNLKKAAIITIGRLSKNVNPLEMSSRIVQALVRVLNTSELEYVKATMNTXXXXXXXXN 1137
S+G+LKK +IIT+GRL+KN+N EMSSRIVQALVR+LN + E KATMNT
Sbjct: 1095 SAGSLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNGDRELTKATMNTLSLLLLQLG 1154
Query: 1138 IDFTVFIPVINKTLVKQNIQHTIYDRLVAKLLNNEPLPTKIIIDKDFDLPNKEMDDVKVA 1197
DF VF+PVINK L++ IQH++YD+LV KLLNNE LPT II DK+ ++P ++ + ++
Sbjct: 1155 TDFVVFVPVINKALLRNRIQHSVYDQLVNKLLNNECLPTNIIFDKENEVPERKNYEDEMQ 1214
Query: 1198 SKKLPVNQLVLKNAWDCSQQRTKEDWQEWIRRLSISLLKESSSHALRACSGLAGIYYPLA 1257
KLPVNQ +LKNAW CSQQ+TKEDWQEWIRRLSI LLKES S LR+CS L +YYPLA
Sbjct: 1215 VTKLPVNQNILKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRSCSSLVSVYYPLA 1274
Query: 1258 RELFNASFASCWGELYTQYQEDLVQSLCSALSSPNNPPEIHQTLLNLVEFMEHDDKPLPI 1317
RELFNASF+SCW EL T YQEDL+Q+LC ALSS NPPEI+Q LLNLVEFMEHDDKPLPI
Sbjct: 1275 RELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLNLVEFMEHDDKPLPI 1334
Query: 1318 SISTLGEYAQRCHAYAKALHYKELEFIEEPTTSTIESLISINNQLHQTDAAIGILKHAQQ 1377
I TLG+YAQ+CHA+AKALHYKE+EF+EEP STIE+LISINNQLHQTD+AIGILKHAQQ
Sbjct: 1335 PIHTLGKYAQKCHAFAKALHYKEVEFLEEPKNSTIEALISINNQLHQTDSAIGILKHAQQ 1394
Query: 1378 HHDLQLKETWYEKLQRWDDALTAYNKREAAGEDSIEVTIGKMRSLHALGDWDQLSELAAD 1437
H++LQLKETWYEKLQRW+DAL AYN++EAAGEDS+EV +GK+RSL+ALG+W++LS+LA++
Sbjct: 1395 HNELQLKETWYEKLQRWEDALAAYNEKEAAGEDSVEVMMGKLRSLYALGEWEELSKLASE 1454
Query: 1438 KWASSKIDIKRXXXXXXXXXXXXXXQWDRIEQYIEVMKPQSPDKAFFAAVLCLHRNNFDK 1497
KW ++K ++K+ QWD I QY VMK QSPDK F+ A+LCLHRNNF K
Sbjct: 1455 KWGTAKPEVKK-AMAPLAAAAWGLEQWDEIAQYTSVMKSQSPDKEFYDAILCLHRNNFKK 1513
Query: 1498 AQEQIFAARDLLVTEMSALVNESYNRAYGVVVRTQMVAELEEIIQYKNLPQGSDRRAMIR 1557
A+ IF ARDLLVTE+SALVNESYNRAY VVVR Q++AELEEII+YK LPQ SD+R +R
Sbjct: 1514 AEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIAELEEIIKYKKLPQNSDKRLTMR 1573
Query: 1558 KTWNKRLLGCQKNVDVWQRILKVRSLVIKPKQDMKVWIKFANLCRKSGRLGLAQKTLNTL 1617
+TWN RLLGCQKN+DVWQRIL+VRSLVIKPK+D +V IKFANLCRKSGR+ LA+K LNTL
Sbjct: 1574 ETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQVRIKFANLCRKSGRMALAKKVLNTL 1633
Query: 1618 LEESSDPKNPNTARAPPPVVYAQLKYMWATGSQKEALNHLISFTSRMAHDLGLDPSNMIA 1677
LEE+ DP +PNTA+A PPVVYAQLKY+WATG Q EAL LI+FTSRMAHDLGLDP+NMIA
Sbjct: 1634 LEETDDPDHPNTAKASPPVVYAQLKYLWATGLQDEALKQLINFTSRMAHDLGLDPNNMIA 1693
Query: 1678 QSVPQNSSVSQHHIEDYTKLLARCFLKQGEWRVSLQPNWRLENPDAILGSYLLATHFDKS 1737
QSVPQ S H+EDYTKLLARCFLKQGEWRV LQP WRL NPD+ILGSYLLATHFD +
Sbjct: 1694 QSVPQQSKRVPRHVEDYTKLLARCFLKQGEWRVCLQPKWRLSNPDSILGSYLLATHFDNT 1753
Query: 1738 WYKAWHNWALANFEVTSSLTQRIKDDKVLTLEDAST-----EFTNG--AVAGLGANE-NF 1789
WYKAWHNWALANFEV S LT K K DAS+ EF NG V A E ++
Sbjct: 1754 WYKAWHNWALANFEVISMLTSVSK--KKQEGSDASSVTDINEFDNGMIGVNTFDAKEVHY 1811
Query: 1790 PPELVQRHVVPAIKGFFRSIALSQSSSLQDTLRLLTLWFKFGGIPEAAQAMHEGFGLIKI 1849
L+ RHV+PAIKGFF SI+LS+SSSLQD LRLLTLWF FGGIPEA QAMHEGF LI+I
Sbjct: 1812 SSNLIHRHVIPAIKGFFHSISLSESSSLQDALRLLTLWFTFGGIPEATQAMHEGFNLIQI 1871
Query: 1850 DNWLEVIPQLISRIHQPNQTVSRSLLSLLADLGKAHPQALVYPLTVAIKSDSVSRQRAAL 1909
WLEV+PQLISRIHQPNQ VSRSLLSLL+DLGKAHPQALVYPL VAIKS+S+SRQ+AAL
Sbjct: 1872 GTWLEVLPQLISRIHQPNQIVSRSLLSLLSDLGKAHPQALVYPLMVAIKSESLSRQKAAL 1931
Query: 1910 SIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQFFGEHNTEKMFATLE 1969
SII+KMR+HSP LVDQAELVS ELIR+AVLWHE WYEGL+DASRQFFGEHNTEKMFA LE
Sbjct: 1932 SIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALE 1991
Query: 1970 PLHEMLKRGPETLREISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYNVFRRIS 2029
PL+EMLKRGPETLREISFQNSFGRDLNDA+EW+MNYK++KD++NLNQAWDIYYNVFR+I
Sbjct: 1992 PLYEMLKRGPETLREISFQNSFGRDLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIG 2051
Query: 2030 RKLPQLQTLDLQHVSPKLAAAKDLELAVPGT-YHAGKPVIRITHFEPIFTVISSKQRPRR 2088
++LPQLQTL+LQHVSPKL +A DLELAVPGT GKP+++I+ FEP+F+VISSKQRPR+
Sbjct: 2052 KQLPQLQTLELQHVSPKLLSAHDLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRK 2111
Query: 2089 LSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLS 2148
IKGSDGKDY+Y++KGHEDIRQD+LVMQLFGLVNTLLQN+ E F+RHL+IQQYPAIPLS
Sbjct: 2112 FCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLS 2171
Query: 2149 PKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYAL 2208
PKSGLLGWVPNSDTFHVLIREHREA K+PLNIEH +MLQMAPDYDNLTLLQKVEVFTYAL
Sbjct: 2172 PKSGLLGWVPNSDTFHVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYAL 2231
Query: 2209 DNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTG 2268
+NT+GQDLYKVLWLKSRSSE+WLERRTTYTRSLAVMSM GYILGLGDRHPSNLMLDR+TG
Sbjct: 2232 NNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITG 2291
Query: 2269 KVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNK 2328
KV+HIDFGDCFEAAILREK+PEKVPFRLTRMLTYAMEVSGIEGSFRITCENVM VLRDNK
Sbjct: 2292 KVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNK 2351
Query: 2329 ESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDAAKMELQ 2388
SLMAILEAFA+DPLINWGFDLPT+ + E+TGI LP+ N +ELL G IT E+ ++E +
Sbjct: 2352 GSLMAILEAFAFDPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAITEEEVQRVENE 2411
Query: 2389 QKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGWCS 2448
K +RNARA LVLKRI DKLTGND R+ +L VP+QVDKLIQQATSVENLCQHYIGWC
Sbjct: 2412 HKNAIRNARAMLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCP 2471
Query: 2449 FW 2450
FW
Sbjct: 2472 FW 2473
>YJR066w [L] KOG0891 DNA-dependent protein kinase
Length = 2470
Score = 3261 bits (8454), Expect = 0.0
Identities = 1627/2417 (67%), Positives = 1962/2417 (80%), Gaps = 16/2417 (0%)
Query: 50 SGEFGAALSDSNVENSVKAF-NLIFTKLKSTSEMERTAASFELRSSLISLAREVSTEHFQ 108
S F + SN + + K IF +L S + ER AS L L+SL E+S E FQ
Sbjct: 54 SSRFDGVVIGSNGDVNFKPILEKIFRELTSDYKEERKLASISLFDLLVSLEHELSIEEFQ 113
Query: 109 RFSNDINNKVFELIHGNDSNEKLGGVLAVDTLIDFYSRTDELPNQTSRLANYLRVLIPSN 168
SNDINNK+ EL+H ++ ++G VL++DTLI FY+ T+ LPN+TSRLA YLR LIPSN
Sbjct: 114 AVSNDINNKILELVHTKKTSTRVGAVLSIDTLISFYAYTERLPNETSRLAGYLRGLIPSN 173
Query: 169 DIEVMRAAAGTLGKLAVPGGTLTSEFVEFEVKTCIEWLTTSPE-NSSSNSKQEYRKHASL 227
D+EVMR AA TLGKLAVPGGT TS+FVEFE+K+C+EWLT S E NS S+SK ++ KHA+L
Sbjct: 174 DVEVMRLAAKTLGKLAVPGGTYTSDFVEFEIKSCLEWLTASTEKNSFSSSKPDHAKHAAL 233
Query: 228 LIISAIADNSPYLLYPFVNSILDNIWRALRDTKLVIRTDASVTLGKCLTIINNRDSSLTK 287
LII+A+A+N PYLLY ++NSILDNIWRALRD LVIR DAS+TL KCL+ + NRD LT
Sbjct: 234 LIITALAENCPYLLYQYLNSILDNIWRALRDPHLVIRIDASITLAKCLSTLRNRDPQLTS 293
Query: 288 KWVQRLFNGCIYGLQLNSTVSIHGTLLVYRQLVSLEGGYLKDKFEEIYETTMRYRENKNI 347
+WVQRL C YG Q+N+ IH +LLVY++++ L+ +L F+++ + Y +K
Sbjct: 294 QWVQRLATSCEYGFQVNTLECIHASLLVYKEILFLKDPFLNQVFDQMCLNCIAYENHKAK 353
Query: 348 IIRKEIYAIIPVLAAFDPKLFTQKYLDSTMIHYLTLLKNM--NSHPVTNSDKGPILISVG 405
+IR++IY I+P+LA+F+P+LF KYL M +YL +L N N P DK ILIS+G
Sbjct: 354 MIREKIYQIVPLLASFNPQLFAGKYLHQIMDNYLEILTNAPANKIPHLKDDKPQILISIG 413
Query: 406 DIAYYVGPDIGPYLDAIVENLRDGLTTKYKFRKDYEQEIFYCIGKLACAVRPLLAKYLNR 465
DIAY VGPDI PY+ I++ + L TK+KFRK +E EIFYCIG+LA + P+L K LNR
Sbjct: 414 DIAYEVGPDIAPYVKQILDYIEHDLQTKFKFRKKFENEIFYCIGRLAVPLGPVLGKLLNR 473
Query: 466 GLLEYMLACPLSDHMQETLLIVCEKIPSLEGTINEKLLNIICLVLSGEKFRPPGSPTPMK 525
+L+ M CPLSD+MQET I+ E+IPSL IN++LLN++C LSG F PGSP +
Sbjct: 474 NILDLMFKCPLSDYMQETFQILTERIPSLGPKINDELLNLVCSTLSGTPFIQPGSPMEIP 533
Query: 526 PFSAETARNYRDQSLFKKTGEANNDIFDAVILTKALRMLSDIKPKYSLTEFIRRVIISYM 585
FS E AR +R++++ +KTGE+N+D D I+ +A RML +IK ++SL EF+R V +SY+
Sbjct: 534 SFSRERAREWRNKNILQKTGESNDDNNDIKIIIQAFRMLKNIKSRFSLVEFVRIVALSYI 593
Query: 586 EHDNLQVRKLAALTSCDLFVEDSICKQTSLYALNVVSEVLSKLLTVAITDPVAEIRLEIL 645
EH + +VRKLAALTSC+++V+D+ICKQTSL++LN VSEVLSKLL + I DP+ +IRLE+L
Sbjct: 594 EHTDPRVRKLAALTSCEIYVKDNICKQTSLHSLNTVSEVLSKLLAITIADPLQDIRLEVL 653
Query: 646 RHLDTNFDPQLSQPDNTKLLFMALNDEVFAIQMEAMRICGRLALVNPAYVIPSLRKTLIQ 705
++L+ FDPQL+QPDN +LLF AL+DE F IQ AM + GRL+ VNPAYVIPS+RK L++
Sbjct: 654 KNLNPCFDPQLAQPDNLRLLFTALHDESFNIQSVAMELVGRLSSVNPAYVIPSIRKILLE 713
Query: 706 LLTELKHSKLTRKKEECASLLCTLISSSSDVTKPYLEPVIEILLPKSQDSSSAVASTALK 765
LLT+LK S +R+KEE ASLLCTLI SS DV KPY+EP++ +LLPK QD+SS VASTAL+
Sbjct: 714 LLTKLKFSTSSREKEETASLLCTLIRSSKDVAKPYIEPLLNVLLPKFQDTSSTVASTALR 773
Query: 766 AIGELSVVGGEDMVPFLDELMPLIIDTFQDQSNSFKRNAALKALGQLSASSGYVIDPLLD 825
IGELSVVGGEDM +L +L PLII TFQDQSNSFKR AALKALGQL+ASSGYVIDPLLD
Sbjct: 774 TIGELSVVGGEDMKIYLKDLFPLIIKTFQDQSNSFKREAALKALGQLAASSGYVIDPLLD 833
Query: 826 YPELLGVLLNILKSESSQNIRRETVRLIGILGALDPYKHREVERTSSTNITVEQNAPPID 885
YPELLG+L+NILK+E+SQNIRR+TV LIGILGA+DPY+ +E E TS+T+I+ EQNAPPID
Sbjct: 834 YPELLGILVNILKTENSQNIRRQTVTLIGILGAIDPYRQKEREVTSTTDISTEQNAPPID 893
Query: 886 VALLMQGMSPSNEEYYPTVVIGVLMKILKDPSLSIHHSTVIQAIMHIFQTMGLRCVIFLK 945
+ALLMQGMSPSN+EYY TVVI L+KILKDPSLS +H+ VIQAIMHIFQT+GL+CV FL
Sbjct: 894 IALLMQGMSPSNDEYYTTVVIHCLLKILKDPSLSSYHTAVIQAIMHIFQTLGLKCVSFLD 953
Query: 946 QIIPGFILVMHTCPPSLLELYFQQLSVLISIVKQHIRLHVSEIVEVISEFFPIVKLQLTI 1005
QIIP + VM TC SLLE YFQQL LI IV+QHIR HV I + I +F + KLQ+T+
Sbjct: 954 QIIPTILDVMRTCSQSLLEFYFQQLCSLIIIVRQHIRPHVDSIFQAIKDFSSVAKLQITL 1013
Query: 1006 ISVIESLSRALEGEFNPYLPNILSLFLDVLEKDQSNKKVVSIRILKSLVVFGPHLEEYAH 1065
+SVIE++S+ALEGEF +P L+LFL +LE D+S+ KV+S R+L+ L FGP+LE Y+H
Sbjct: 1014 VSVIEAISKALEGEFKRLVPLTLTLFLVILENDKSSDKVLSRRVLRLLESFGPNLEGYSH 1073
Query: 1066 LVLPTIIKLSEFSSGNLKKAAIITIGRLSKNVNPLEMSSRIVQALVRVLN-TSELEYVKA 1124
L+ P I++++EF+SGNL+++AIITIG+L+K+V+ EMSSRIV +L+RVL+ T+ E K
Sbjct: 1074 LITPKIVQMAEFTSGNLQRSAIITIGKLAKDVDLFEMSSRIVHSLLRVLSSTTSDELSKV 1133
Query: 1125 TMNTXXXXXXXXNIDFTVFIPVINKTLVKQNIQHTIYDRLVAKLLNNEPLPTKIIIDKDF 1184
MNT F +FIPVIN+ L+K++IQHTIYD L ++LNN+ LPTKI+
Sbjct: 1134 IMNTLSLLLIQMGTSFAIFIPVINEVLMKKHIQHTIYDDLTNRILNNDVLPTKILEANTT 1193
Query: 1185 DL-PNKEMDDVKVASKKLPVNQLVLKNAWDCSQQRTKEDWQEWIRRLSISLLKESSSHAL 1243
D P ++M+ KLP+NQ VLK+AW+ SQQRTKEDWQEW +RLSI LLKES SHAL
Sbjct: 1194 DYKPAEQMEAADAGVAKLPINQSVLKSAWNSSQQRTKEDWQEWSKRLSIQLLKESPSHAL 1253
Query: 1244 RACSGLAGIYYPLARELFNASFASCWGELYTQYQEDLVQSLCSALSSPNNPPEIHQTLLN 1303
RACS LA +YYPLA+ELFN +FA W ELY+QYQEDL+ SLC ALSSP NPPEIHQTLLN
Sbjct: 1254 RACSNLASMYYPLAKELFNTAFACVWTELYSQYQEDLIGSLCIALSSPLNPPEIHQTLLN 1313
Query: 1304 LVEFMEHDDKPLPISISTLGEYAQRCHAYAKALHYKELEFIEEPTTSTIESLISINNQLH 1363
LVEFMEHDDK LPI +LGEYA+RCHAYAKALHYKE++FI+EP STIESLISINNQL+
Sbjct: 1314 LVEFMEHDDKALPIPTQSLGEYAERCHAYAKALHYKEIKFIKEPENSTIESLISINNQLN 1373
Query: 1364 QTDAAIGILKHAQQHHDLQLKETWYEKLQRWDDALTAYNKREAAGEDSIEVTIGKMRSLH 1423
QTDAAIGILKHAQQHH LQLKETW+EKL+RW+DAL AYN+RE AG+ S+ VT+GKMRSLH
Sbjct: 1374 QTDAAIGILKHAQQHHSLQLKETWFEKLERWEDALHAYNEREKAGDTSVSVTLGKMRSLH 1433
Query: 1424 ALGDWDQLSELAADKWASSKIDIKRXXXXXXXXXXXXXXQWDRIEQYIEVMKPQSPDKAF 1483
ALG+W+QLS+LAA KW SK+ K+ +WD +EQYI VMKP+SPDK F
Sbjct: 1434 ALGEWEQLSQLAARKWKVSKLQTKKLIAPLAAGAAWGLGEWDMLEQYISVMKPKSPDKEF 1493
Query: 1484 FAAVLCLHRNNFDKAQEQIFAARDLLVTEMSALVNESYNRAYGVVVRTQMVAELEEIIQY 1543
F A+L LH+N++D A + I ARDLLVTE+SAL+NESYNRAY V+VRTQ++ E EEII+Y
Sbjct: 1494 FDAILYLHKNDYDNASKHILNARDLLVTEISALINESYNRAYSVIVRTQIITEFEEIIKY 1553
Query: 1544 KNLPQGSDRRAMIRKTWNKRLLGCQKNVDVWQRILKVRSLVIKPKQDMKVWIKFANLCRK 1603
K LP S+++ + W KRLLGCQKNVD+WQR+L+VRSLVIKPKQD+++WIKFANLCRK
Sbjct: 1554 KQLPPNSEKKLHYQNLWTKRLLGCQKNVDLWQRVLRVRSLVIKPKQDLQIWIKFANLCRK 1613
Query: 1604 SGRLGLAQKTLNTLLEESSDPKNPNTARAPPPVVYAQLKYMWATGSQKEALNHLISFTSR 1663
SGR+ LA K LN LLE +DP PNT +APPPVVYAQLKY+WATG+ KEALNHLI FTSR
Sbjct: 1614 SGRMRLANKALNMLLEGGNDPSLPNTFKAPPPVVYAQLKYIWATGAYKEALNHLIGFTSR 1673
Query: 1664 MAHDLGLDPSNMIAQSVPQNSSVSQHHIEDYTKLLARCFLKQGEWRVSLQPNWRLENPDA 1723
+AHDLGLDP+NMIAQSV +S+ + ++E+YTKLLARCFLKQGEWR++ QPNWR NPDA
Sbjct: 1674 LAHDLGLDPNNMIAQSVKLSSASTAPYVEEYTKLLARCFLKQGEWRIATQPNWRNTNPDA 1733
Query: 1724 ILGSYLLATHFDKSWYKAWHNWALANFEVTSSLTQRIKDDKVLTLEDASTEFTN------ 1777
ILGSYLLATHFDK+WYKAWHNWALANFEV S + + K + +D T N
Sbjct: 1734 ILGSYLLATHFDKNWYKAWHNWALANFEVISMVQEETKLNGGKNDDDDDTAVNNDNVRID 1793
Query: 1778 GAVAGLGA----NENFPPELVQRHVVPAIKGFFRSIALSQSSSLQDTLRLLTLWFKFGGI 1833
G++ G G+ +P EL+QRHVVPAIKGFF SI+L ++S LQDTLRLLTL F FGGI
Sbjct: 1794 GSILGSGSLTINGNRYPLELIQRHVVPAIKGFFHSISLLETSCLQDTLRLLTLLFNFGGI 1853
Query: 1834 PEAAQAMHEGFGLIKIDNWLEVIPQLISRIHQPNQTVSRSLLSLLADLGKAHPQALVYPL 1893
E +QAM+EGF L+KI+NWLEV+PQLISRIHQP+ TVS SLLSLL+DLGKAHPQALVYPL
Sbjct: 1854 KEVSQAMYEGFNLMKIENWLEVLPQLISRIHQPDPTVSNSLLSLLSDLGKAHPQALVYPL 1913
Query: 1894 TVAIKSDSVSRQRAALSIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASR 1953
TVAIKS+SVSRQ+AALSII+K+R+HSP LV+QAELVS ELIRVAVLWHELWYEGLEDASR
Sbjct: 1914 TVAIKSESVSRQKAALSIIEKIRIHSPVLVNQAELVSHELIRVAVLWHELWYEGLEDASR 1973
Query: 1954 QFFGEHNTEKMFATLEPLHEMLKRGPETLREISFQNSFGRDLNDAHEWVMNYKRTKDINN 2013
QFF EHN EKMF+TLEPLH+ L P+TL E+SFQ SFGRDLNDA+EW+ NYK++KDINN
Sbjct: 1974 QFFVEHNIEKMFSTLEPLHKHLGNEPQTLSEVSFQKSFGRDLNDAYEWLNNYKKSKDINN 2033
Query: 2014 LNQAWDIYYNVFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAGKPVIRITHF 2073
LNQAWDIYYNVFR+I+R++PQLQTLDLQHVSP+L A DLELAVPGTY GKP IRI F
Sbjct: 2034 LNQAWDIYYNVFRKITRQIPQLQTLDLQHVSPQLLATHDLELAVPGTYFPGKPTIRIAKF 2093
Query: 2074 EPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESF 2133
EP+F+VISSKQRPR+ SIKGSDGKDY+Y++KGHEDIRQD+LVMQLFGLVNTLL+N+ E F
Sbjct: 2094 EPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLKNDSECF 2153
Query: 2134 QRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYD 2193
+RHL+IQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHR+A K+PLNIEH +MLQMAPDY+
Sbjct: 2154 KRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHRDAKKIPLNIEHWVMLQMAPDYE 2213
Query: 2194 NLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGL 2253
NLTLLQK+EVFTYALDNTKGQDLYK+LWLKSRSSE+WLERRTTYTRSLAVMSM GYILGL
Sbjct: 2214 NLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGL 2273
Query: 2254 GDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSF 2313
GDRHPSNLMLDR+TGKV+HIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSF
Sbjct: 2274 GDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSF 2333
Query: 2314 RITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLR 2373
RITCENVM VLRDNKESLMAILEAFA DPLI+WGFDLP Q + EQTGI LPL NPSELLR
Sbjct: 2334 RITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQKLTEQTGIPLPLINPSELLR 2393
Query: 2374 KGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQA 2433
KG ITVE+AA ME +Q+ E +NARA LVL+RI DKLTGND R+ EL VP+QVDKLIQQA
Sbjct: 2394 KGAITVEEAANMEAEQQNETKNARAMLVLRRITDKLTGNDIKRFNELDVPEQVDKLIQQA 2453
Query: 2434 TSVENLCQHYIGWCSFW 2450
TS+E LCQHYIGWC FW
Sbjct: 2454 TSIERLCQHYIGWCPFW 2470
>SPBC216.07c [L] KOG0891 DNA-dependent protein kinase
Length = 1973
Score = 2150 bits (5572), Expect = 0.0
Identities = 1097/2003 (54%), Positives = 1447/2003 (71%), Gaps = 63/2003 (3%)
Query: 467 LLEYMLACPLSDHMQETLLIVCEKIPSLEGTINEKLLNIICLVLSGEKFRPPGSPTPMKP 526
L + + A LS+ L + IP L I E+LL+++ +LSG F PPG P
Sbjct: 15 LFDLIFASGLSEASYRALSDLAHNIPPLLPVIQERLLDMLSKILSGRPFIPPGCPPQ--- 71
Query: 527 FSAETARNYRDQSLFKKTGEANNDIFDAVILTKALRMLSDIK-PKYSLTEFIRRVIISYM 585
+ A + ++ + SL KTG ND++ AL++L + Y L EF++ ++ Y+
Sbjct: 72 YVARSLKSSKSASL--KTGFFPNDVY-----ILALKVLGNFDFSGYILNEFVKDCVVVYL 124
Query: 586 EHDNLQVRKLAALTSCDLFVEDSICKQTSLYALNVVSEVLSKLLTVAITDPVAEIRLEIL 645
E+++ +VRK A++T LF D I QTS +A+ VV+EVL KLLTV I D V +IRL +L
Sbjct: 125 ENNDPEVRKTASITCSQLFARDPILSQTSDHAIQVVAEVLEKLLTVGICDTVPDIRLTVL 184
Query: 646 RHLDTNFDPQLSQPDNTKLLFMALNDEVFAIQMEAMRICGRLALVNPAYVIPSLRKTLIQ 705
LD+ F+ L+Q D +LLF+A+NDE FA++ A+RI GRL + NPAYV+P LRK +++
Sbjct: 185 NSLDSRFNKHLAQADKIRLLFIAINDENFAVRESALRIIGRLNVYNPAYVMPYLRKIMLK 244
Query: 706 LLTELKHSKLTRKKEECASLLCTLISSSSDVTKPYLEPVIEILLPKSQDSSSAVASTALK 765
LT L +S + R KEE A LLC LI+++ + + ++EP+++ILLPK++DSSS VA++ +
Sbjct: 245 TLTILDYSTIIRTKEENAKLLCLLIAAAPRLIESHVEPILQILLPKAKDSSSIVAASIVN 304
Query: 766 AIGELSVVGGEDMVPFLDELMPLIIDTFQDQSNSFKRNAALKALGQLSASSGYVIDPLLD 825
++GE+ + GE +VPF+ +LMPLII+ QDQS+ +R AALKALG LS+S+GYVIDP ++
Sbjct: 305 SLGEICQISGEVIVPFIKDLMPLIIEALQDQSSPIRRAAALKALGNLSSSTGYVIDPYIE 364
Query: 826 YPELLGVLLNILKSESSQNIRRETVRLIGILGALDPYKHREVERTSSTNITVEQNAPPID 885
+P LL +L+ I K+E IRRET++LIG LGALDP +HR +E+ + + ++N PP D
Sbjct: 365 FPSLLDILIGITKTEQDITIRRETIKLIGTLGALDPNRHRVLEKGTEKVVPEQKNIPP-D 423
Query: 886 VALLMQGMSPSNEEYYPTVVIGVLMKILKDPSLSIHHSTVIQAIMHIFQTMGLRCVIFLK 945
++LLM G+ PS++EYYPTVVI LM ILKDPSL+IHH+ VIQA+M+IF+TMGLRC FL
Sbjct: 424 ISLLMSGIGPSSDEYYPTVVITALMSILKDPSLTIHHTAVIQAVMYIFKTMGLRCAPFLS 483
Query: 946 QIIPGFILVMHTCPPSLLELYFQQLSVLISIVKQHIRLHVSEIVEVISEFF-PIVKLQLT 1004
QIIP FI VM TCP ++LE YFQQLS+L+ IV+QHIR + ++ ++I +F+ P LQ T
Sbjct: 484 QIIPEFIAVMRTCPTNILEFYFQQLSILVLIVRQHIRSFLPDLFKLIKDFWNPHSNLQFT 543
Query: 1005 IISVIESLSRALEGEFNPYLPNILSLFLDVLEKDQSNKKVVSIRILKSLVVFGPHLEEYA 1064
I+S+IESL+RA++GEF PYLP++L + L + + D S V + ++L + +VFG L +Y
Sbjct: 544 ILSLIESLARAMQGEFKPYLPSLLVMMLQIFDSDVSVDSVSTKKVLHAFIVFGDTLADYF 603
Query: 1065 HLVLPTIIKLSEFS--SGNLKKAAIITIGRLSKNVNPLEMSSRIVQALVRVLNTSELEYV 1122
H++L I++L E + S +K++ +ITIGRLS +N E +SRI+ ++R+L+ + +
Sbjct: 604 HMLLDPILRLYERNDVSIGIKESIMITIGRLSMVINLSEYASRIIHPVMRMLSCNNASLI 663
Query: 1123 KATMNTXXXXXXXXNIDFTVFIPVINKTLVKQNIQHTIYDRLVAKLLNNEPLPTKIIIDK 1182
+ +M+T N+DF +FIP+I+K L + H Y LV + L +PLP K+ +
Sbjct: 664 RVSMDTVCALIYQLNVDFAIFIPMIDKCLKMNGVTHETYSILVEQFLQEQPLPIKLNPYE 723
Query: 1183 DFDLPNKEM--DDVKVASKKLPVNQLVLKNAWDCSQQRTKEDWQEWIRRLSISLLKESSS 1240
+D P ++ + SKKLPVNQ +L+NAW+ SQ+ TK+DWQEWIRRL ++LL+ES S
Sbjct: 724 KYDKPKLDVVASAADITSKKLPVNQEILRNAWEASQRSTKDDWQEWIRRLGVALLRESPS 783
Query: 1241 HALRACSGLAGIYYPLARELFNASFASCWGELYTQYQEDLVQSLCSALSSPNNPPEIHQT 1300
HALRAC+ LA Y PLAR+LFNASF SCW ELY +QE+LV+S+ AL+SP+ PEI Q
Sbjct: 784 HALRACAALAAAYQPLARDLFNASFVSCWSELYDHFQEELVKSIEIALTSPHISPEIIQI 843
Query: 1301 LLNLVEFMEHDDKPLPISISTLGEYAQRCHAYAKALHYKELEFIEE-----PTTSTIESL 1355
LLNL EFMEHDDKPLPI I TLG YA +CHA+AKALHYKELEFIEE P+ TIE+L
Sbjct: 844 LLNLAEFMEHDDKPLPIDIRTLGAYAAKCHAFAKALHYKELEFIEEELVTKPSVDTIEAL 903
Query: 1356 ISINNQLHQTDAAIGILKHAQQHHDLQLKETWYEKLQRWDDALTAYNKREAAGEDSIEVT 1415
ISINNQL Q DAAIGILKHAQQH + LKETWYEKLQRW+DAL+AY KREAAG + E+T
Sbjct: 904 ISINNQLQQPDAAIGILKHAQQHDKMNLKETWYEKLQRWEDALSAYEKREAAGAGNFEIT 963
Query: 1416 IGKMRSLHALGDWDQLSELAADKWASSKIDIKRXXXXXXXXXXXXXXQWDRIEQYIEVMK 1475
+GK+R LHALG+WD+LS+LA + W + D +R QW+++++YI VMK
Sbjct: 964 MGKLRCLHALGEWDRLSQLAQENWIHAGHDARRYIAPLSVAAAWGLGQWEQMDEYISVMK 1023
Query: 1476 PQSPDKAFFAAVLCLHRNNFDKAQEQIFAARDLLVTEMSALVNESYNRAYGVVVRTQMVA 1535
+SPDKAFF A++ LHR+ F++A I ARDLL TE++ALV ESYNRAY V VR QM++
Sbjct: 1024 SESPDKAFFNAIVALHRSQFEEAASYITRARDLLDTELTALVGESYNRAYSVAVRVQMLS 1083
Query: 1536 ELEEIIQYKNLPQGSDRRAMIRKTWNKRLLGCQKNVDVWQRILKVRSLVIKPKQDMKVWI 1595
ELEEII YK + R MI+KTW +RL GCQ+NVDVWQR+L++RSLVI P+ +M++WI
Sbjct: 1084 ELEEIITYKKAEDKPEVREMIKKTWVRRLKGCQRNVDVWQRMLRIRSLVISPRDNMEMWI 1143
Query: 1596 KFANLCRKSGRLGLAQKTLNTLLEESSDPKNPNTARAP-PPVVYAQLKYMWATGSQKEAL 1654
KFANLCRKSGR+ LA+K+LN LLE+ + N + P +VYA LK++WA +++AL
Sbjct: 1144 KFANLCRKSGRISLAKKSLNLLLEDDENLDNSLVLKKTHPSIVYANLKFLWAVDDKRKAL 1203
Query: 1655 NHLISFTSRMAHDLGLDPSNMIAQSVPQNSSVSQHHIEDYTKLLARCFLKQGEWRVSLQP 1714
N + FTS++ D+ +DP+ + QS N+ SQ I+ Y LLARC+ KQG+W+ ++
Sbjct: 1204 NSMQEFTSQLISDINVDPA-LFVQSTSVNTQKSQEEIQYYFHLLARCYHKQGQWQQEIEN 1262
Query: 1715 NWRLENPDAILGSYLLATHFDKSWYKAWHNWALANFEVTSSLTQRIKDDKVLTLEDASTE 1774
NW + D +L SY+ AT FD WYKAWH+WALANFE L Q
Sbjct: 1263 NWSEGSFDGVLQSYMYATQFDSKWYKAWHSWALANFEAVKFLEQ---------------- 1306
Query: 1775 FTNGAVAGLGANENFPPELVQRHVVPAIKGFFRSIALSQSSSLQDTLRLLTLWFKFGGIP 1834
+ E P +++++PA+KGFF+SIALS+ + LQDTLRLL LWFKFG
Sbjct: 1307 ----------SEEQIPSAAYEQYIIPAVKGFFKSIALSKGN-LQDTLRLLNLWFKFGNNS 1355
Query: 1835 EAAQAMHEGFGLIKIDNWLEVIPQLISRIHQPNQTVSRSLLSLLADLGKAHPQALVYPLT 1894
++ G + ID WL+VIPQLI+RIH + +V +S+ LL+D+G+AHPQALVYPLT
Sbjct: 1356 NVINTLNVGISTVNIDIWLDVIPQLIARIHASSLSVRKSVHQLLSDVGRAHPQALVYPLT 1415
Query: 1895 VAIKSDSVSRQRAALSIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQ 1954
VA KS S +RQ AAL+I+D ++ HSP+LV+QA LVS ELIR A+LWHE W+EGLE+ASR
Sbjct: 1416 VAAKSQSSARQNAALAIMDSLKTHSPRLVEQARLVSHELIRAAILWHEQWHEGLEEASRL 1475
Query: 1955 FFGEHNTEKMFATLEPLHEMLKRGPETLREISFQNSFGRDLNDAHEWVMNYKRTKDINNL 2014
+FG+HN E MFA L PLHEML+RGPETLREISFQ +FGRDL +A + + +++T DI++L
Sbjct: 1476 YFGDHNIEGMFAVLRPLHEMLERGPETLREISFQQAFGRDLVEARDCCIRFEQTGDISDL 1535
Query: 2015 NQAWDIYYNVFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAGKPVIRITHFE 2074
NQAWD+YY VF++I ++LPQL TLDLQ+VSPKL DLELAVPGTY +GKPVIRI F
Sbjct: 1536 NQAWDLYYQVFKKIRKQLPQLTTLDLQYVSPKLLHVHDLELAVPGTYVSGKPVIRIVKFY 1595
Query: 2075 PIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQ 2134
P F VI+SKQRPRRLSIKGSDGKDYQY++KGHEDIRQD VMQLFGL N LL +PE+F+
Sbjct: 1596 PTFNVITSKQRPRRLSIKGSDGKDYQYVLKGHEDIRQDERVMQLFGLCNNLLLADPETFK 1655
Query: 2135 RHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDN 2194
R L+IQ+YP IPLSP SGLLGWV +SDT HVLIR++RE+ K+ LNIEHR+++QMAPDYD
Sbjct: 1656 RLLSIQRYPVIPLSPDSGLLGWVLDSDTLHVLIRDYRESRKILLNIEHRLIIQMAPDYDR 1715
Query: 2195 LTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLG 2254
LTLLQKVEVF YAL +T GQDLY+VLWLKSRSSE+WL RRT Y+R+LAVMSMVGYILGLG
Sbjct: 1716 LTLLQKVEVFEYALLSTTGQDLYRVLWLKSRSSEAWLNRRTNYSRTLAVMSMVGYILGLG 1775
Query: 2255 DRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFR 2314
DRHPSNLMLDR TG ++HIDFGDCFE A+ REK+PEK+PFRLTRML AMEVSGIEG+FR
Sbjct: 1776 DRHPSNLMLDRYTGNIIHIDFGDCFEVAMHREKFPEKIPFRLTRMLVNAMEVSGIEGTFR 1835
Query: 2315 ITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLAN-PSELLR 2373
ITCE+VM VLR NKES+MA+LEAF YDPLINW A ID +N P+ LL
Sbjct: 1836 ITCEHVMRVLRTNKESVMAVLEAFVYDPLINWRL-----APAYSPSIDEKQSNEPNTLLG 1890
Query: 2374 KGVITV------EDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVD 2427
+ + + E+ +E +QK E+ N RA VL R+++KLTG DF Q+L VP QV+
Sbjct: 1891 ETIDGLHRKRLNEEGITLEERQKPEILNQRAITVLNRVSNKLTGRDFKPQQQLDVPSQVE 1950
Query: 2428 KLIQQATSVENLCQHYIGWCSFW 2450
KLI QATS+ENLC YIGWCSFW
Sbjct: 1951 KLILQATSIENLCLCYIGWCSFW 1973
>SPBC30D10.10c [L] KOG0891 DNA-dependent protein kinase
Length = 2335
Score = 2066 bits (5352), Expect = 0.0
Identities = 1126/2399 (46%), Positives = 1543/2399 (63%), Gaps = 88/2399 (3%)
Query: 73 FTKLKSTSEMERTAASFELRSSLISLAREVSTEHFQRFSNDINNKVFELIHGNDSNEKLG 132
F+ LK+ +E + AA+ +L+ + S +E+S E RF+NDIN ++FELIH +DS+E+ G
Sbjct: 4 FSDLKNKNESIQLAAADQLKEFVHSSTKELSGESLARFNNDINRRIFELIHSHDSHERFG 63
Query: 133 GVLAVDTLIDFYSRTDELPNQTSRLANYLRVLIPSNDIEVMRAAAGTLGKLAVPGGTLTS 192
G+LA+ LI+F S D SR ANYLR+ +PS D M +A LG LA GGTL +
Sbjct: 64 GILAIGKLIEFESEGDV--TNLSRYANYLRMTLPSTDWHSMELSAKVLGHLAASGGTLAA 121
Query: 193 EFVEFEVKTCIEWLTTSPENSSSNSKQEYRKHASLLIISAIADNSPYLLYPFVNSILDNI 252
EFVEFEV+ EWL +QE ++ A++LII A+A NSP L+Y +++ I N+
Sbjct: 122 EFVEFEVQRAFEWL--------QGDRQEQKRMAAILIIKALAQNSPTLVYLYISEIFQNL 173
Query: 253 WRALRDTKLVIRTDASVTLGKCLTIINNRDSSLTKKWVQRLFNGCIYGLQLNSTVSIHGT 312
W LRD K +IR A+ LG L ++ R++ + + + +GL+ +S +HG+
Sbjct: 174 WTGLRDPKPLIRETAADALGASLDVVCQREAKVQLQCFNEVLLQAEHGLRQSSVEYLHGS 233
Query: 313 LLVYRQLVSLEGGYLKDKFEEIYETTMRYRENKNIIIRKEIYAIIPVLAAFDPKLFTQKY 372
LL Y++L G ++++ + E + +R RE+++ IR+ I ++P L+ ++PK F Q+Y
Sbjct: 234 LLAYKELFEKSGSFIREHYTEFCDLALRLREHRDNSIRRCIVFLLPTLSEYNPKKFQQRY 293
Query: 373 LDSTMIHYLTLLKNMNSHPVTNSDKGPILISVGDIAYYVGPDIGPYLDAIVENLRDGLTT 432
LDS M++ L SH + +K ++G IA V + PYL I++ +RD LT
Sbjct: 294 LDSFMVYLL-------SHIRKDKEKSLAFEAIGRIAMAVNEAMIPYLQNILKVIRDTLTA 346
Query: 433 KYKFRKDYEQEIFYCIGKLACAVRPLLAKYLNRGLLEYMLACPLSDHMQETLLIVCEKIP 492
K + + YE+ +F CIG LA AV+ L + +R LL + +C LS H+++ L+ + E IP
Sbjct: 347 KVREKTQYEKPVFECIGMLAAAVKLELLED-SRSLLGLIFSCELSVHLRQALVKMAENIP 405
Query: 493 SLEGTINEKLLNIICLVLSGEKFRPPGSPTPMKPFSAETARNYRDQSLFKKTGEANNDIF 552
L I E+LLN++ +L+G+ F + T F+ + DQ K T
Sbjct: 406 PLLAPIQERLLNMVSQILTGKNFEIRTNDTYTPSFTNIYSAREPDQRS-KST-------- 456
Query: 553 DAVILTKALRMLSDIK-PKYSLTEFIRRVIISYMEHDNLQVRKLAALTSCDLFVEDSICK 611
+++IL AL L YSL FI+ ++SY+E+DN ++R AA T C +F D IC+
Sbjct: 457 ESIIL--ALETLGTFNFTGYSLISFIQESVLSYLENDNSEIRIAAARTCCQVFARDPICR 514
Query: 612 QTSLYALNVVSEVLSKLLTVAITDPVAEIRLEILRHLDTNFDPQLSQPDNTKLLFMALND 671
+T+ A+ V+EVL KLLT+ I D +IR +L LD FD L+ PDN + LF+ALND
Sbjct: 515 KTNPLAVESVAEVLEKLLTLGIADSDPKIRETVLSLLDERFDRHLAHPDNIRCLFIALND 574
Query: 672 EVFAIQMEAMRICGRLALVNPAYVIPSLRKTLIQLLTELKHSKLTRKKEECASLLCTLIS 731
EVF+I+ A+ I GRLAL NPA+V+PSLRKT+IQLL+++++S +R+KEE A LL L+S
Sbjct: 575 EVFSIREIAIIIIGRLALYNPAHVMPSLRKTIIQLLSDMEYSGNSRQKEESAQLLKLLVS 634
Query: 732 SSSDVTKPYLEPVIEILLPKSQDSSSAVASTALKAIGELSVVGGEDM-VPFLDELMPLII 790
+ + KPY++ +I ++LPK+ D+S V+S + A+GEL+ V GEDM V M LI+
Sbjct: 635 KARTLIKPYIQSIIHVILPKAADTSPGVSSAIISALGELASVEGEDMPVDVRGSFMKLIL 694
Query: 791 DTFQDQSNSFKRNAALKALGQLSASSGYVIDPLLDYPELLGVLLNILKSESSQNIRRETV 850
QDQS++ KR A+LK L +L SGYVI P LDYP LLG L+ IL+SE IRRE +
Sbjct: 695 VNLQDQSSTLKRLASLKCLRKLCGRSGYVIQPYLDYPPLLGALIGILQSEQPTPIRREVL 754
Query: 851 RLIGILGALDPYKHREVERTSSTNITVEQNAPPIDVALLMQGMSPSNEEYYPTVVIGVLM 910
R +G+LGALDPY + E S + NA V + PS E Y V+ L+
Sbjct: 755 RTLGVLGALDPYTYLTTEEVSDDLQSSHNNAH--GVPQISAAQYPSLENYAMVAVV-TLI 811
Query: 911 KILKDPSLSIHHSTVIQAIMHIFQTMGLRCVIFLKQIIPGFILVMHTCPPSLLELYFQQL 970
ILKD SLS+HHS+V+QA+MHI MG + +FL Q++P F+ VM + S E YFQQL
Sbjct: 812 GILKDSSLSMHHSSVVQAVMHICSQMGSKSTVFLPQVVPTFLQVMQSLSASSAEFYFQQL 871
Query: 971 SVLISIVKQHIRLHVSEIVEVISEFFP-IVKLQLTIISVIESLSRALEGEFNPYLPNILS 1029
+ L SI+ +IR +VS+I + F+ L L I+ +I++++ AL+ EF YLP ILS
Sbjct: 872 TTLTSIIGPNIRDYVSDIFNLSKVFWESTTSLLLVILELIDAIAIALQDEFKFYLPQILS 931
Query: 1030 LFLDVLEKDQSNKKVVSIRILKSLVVFGPHLEEYAHLVLPTIIKLSEFSSGNL--KKAAI 1087
L D ++ + VS ++L+S V+FG ++EEY HLVLP II+ E + L +K+A+
Sbjct: 932 CMLKAFSLDNTSSRSVSYKVLQSFVIFGSNIEEYMHLVLPVIIRSFERDTIPLGFRKSAL 991
Query: 1088 ITIGRLSKNVNPLEMSSRIVQALVRVLNTSELEYVKATMNTXXXXXXXXNIDFTVFIPVI 1147
I +L ++VN + +SRI+ LVR+L S + M+T D+++FIP++
Sbjct: 992 KCIAQLFQSVNFSDHASRIIHPLVRMLGKSNGDLRAVIMDTLCAIVSQLGYDYSIFIPMV 1051
Query: 1148 NKTLVKQNIQHTIYDRLVAKLLNNEPLPTKIIIDKDFDLPN-KEMDDVKVASKKLPVNQL 1206
NK LV I H Y+ LV++LL EPLP +++ + P+ K KLPV+Q
Sbjct: 1052 NKVLVSHKISHPAYELLVSRLLKGEPLPKDVVVKEFKPRPSTKPFSTQDEVLTKLPVDQA 1111
Query: 1207 VLKNAWDCSQQRTKEDWQEWIRRLSISLLKESSSHALRACSGLAGIYYPLARELFNASFA 1266
LK AW+ SQ+ T++DWQ+WIRR+SI LLKES S ALR+CS LAGIY+PLAR+LFN SF
Sbjct: 1112 SLKAAWESSQKLTRDDWQDWIRRISIELLKESPSSALRSCSTLAGIYHPLARDLFNVSFL 1171
Query: 1267 SCWGELYTQYQEDLVQSLCSALSSPNNPPEIHQTLLNLVEFMEHDDKPLPISISTLGEYA 1326
SCW EL +++LV+S+ A+++PN EI QTLLNL E+ME +D LPI I + +A
Sbjct: 1172 SCWDELTESNKKNLVKSIELAMNAPNISVEILQTLLNLAEYMEREDHTLPIPIKVISAHA 1231
Query: 1327 QRCHAYAKALHYKELEFI----EEPTTSTIESLISINNQLHQTDAAIGILKHAQQHHDLQ 1382
+C+ YAKALHY EL+F+ EE + STIESLI+INN L Q+DAA+G+L++ ++H
Sbjct: 1232 SKCNVYAKALHYTELQFVQETKEEVSISTIESLITINNHLQQSDAAVGMLQYTKEHKQFS 1291
Query: 1383 LKETWYEKLQRWDDALTAYNKREAAGEDSIEVTIGKMRSLHALGDWDQLSELAADKWASS 1442
LKETWYEKL RWDDAL AY RE G+ S E+ IGK+R +ALGDWD LSELA W +S
Sbjct: 1292 LKETWYEKLHRWDDALAAYEHREREGDSSFEINIGKLRCYYALGDWDHLSELAQKAWVTS 1351
Query: 1443 KIDIKRXXXXXXXXXXXXXXQWDRIEQYIEVMKPQSPDKAFFAAVLCLHRNNFDKAQEQI 1502
+ + + QW+ I +Y+ M DK FF+A+ +H ++KA I
Sbjct: 1352 EQEHREAIAPLAAAAAWGLGQWNLISEYVSAMDRDPQDKEFFSAISAVHLGQYNKAYGHI 1411
Query: 1503 FAARDLLVTEMSALVNESYNRAYGVVVRTQMVAELEEIIQYKNLPQGSDRRAMIRKTWNK 1562
RD+LV ++S+++ ESYNRAYG++V++QM++ELEEII YK Q + ++KTW K
Sbjct: 1412 ERHRDILVNDLSSIIGESYNRAYGIMVKSQMLSELEEIIDYKKNMQYENNLDSLKKTWRK 1471
Query: 1563 RLLGCQKNVDVWQRILKVRSLVIKPKQDMKVWIKFANLCRKSGRLGLAQKTLNTLLEESS 1622
RL GCQKNVDVW L+ R+LV+ P+ ++WIK A+LCR+S RL L+ + L L+
Sbjct: 1472 RLEGCQKNVDVWHNTLRFRALVLSPQDSPEMWIKLADLCRRSDRLKLSNQCLTYLM--GR 1529
Query: 1623 DPKN----PNTARAPPPVVYAQLKYMWATGSQKEALNHLISFTSRMAHDLGL---DPSNM 1675
DP N + P VVY LKY+WAT + A++ L FTS ++ G D S +
Sbjct: 1530 DPSNAYPLDSLKLLNPHVVYTYLKYLWATDQKNIAVSELEEFTSYLSSKHGYKMGDSSKL 1589
Query: 1676 IAQSVPQNSSVSQHHIEDYTKLLARCFLKQGEWRVSLQPNWRLENPDAILGSYLLATHFD 1735
+ + +SSVS + LARCF K G+W+ SLQ + E+ IL Y AT FD
Sbjct: 1590 V--DILASSSVS----SEERSFLARCFHKLGKWKKSLQDSVNQESVRDILNCYFYATLFD 1643
Query: 1736 KSWYKAWHNWALANFEVTSSLTQRIKDDKVLTLEDASTEFTNGAVAGLGANENFPPELVQ 1795
KSWYKAWH+WALANFEV Q ++ +
Sbjct: 1644 KSWYKAWHSWALANFEVVGYYEQ--------------------------TEHGVTQDMYE 1677
Query: 1796 RHVVPAIKGFFRSIALSQSSSLQDTLRLLTLWFKFGGIPEAAQAMHEGFGLIKIDNWLEV 1855
+++VPAIKGFF S L+Q +SLQD LRLL LWFKFG + A A+ EGF + +D WLEV
Sbjct: 1678 QYIVPAIKGFFHSSVLNQKNSLQDILRLLNLWFKFGEHSDVAAAIVEGFSNVPMDTWLEV 1737
Query: 1856 IPQLISRIHQPNQTVSRSLLSLLADLGKAHPQALVYPLTVAIKSDSVSRQRAALSIIDKM 1915
IPQLI+RIH + +V S+ LL+D+G+ HPQALVY LTV+ KS + ++ +A SI+D M
Sbjct: 1738 IPQLIARIHTSSSSVRASVHQLLSDIGRVHPQALVYSLTVSSKSTNPQQKHSAKSIMDSM 1797
Query: 1916 RMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQFFGEHNTEKMFATLEPLHEML 1975
HS LV QA LVS ELIRVA+LWHELWYEGLE+AS+ +F +H+ M ++PLHE L
Sbjct: 1798 LSHSDTLVRQALLVSQELIRVAILWHELWYEGLEEASQAYFSDHDISLMIDIVKPLHETL 1857
Query: 1976 KRGPETLREISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYNVFRRISRKLPQL 2035
++GP TL EISF +FG DL A + + + D LNQ+WD+YY VFRRI ++LP++
Sbjct: 1858 EKGPSTLSEISFAQTFGYDLRKARSYWQKFLQDGDPTELNQSWDLYYQVFRRIQKQLPRI 1917
Query: 2036 QTLDLQHVSPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSD 2095
+ L+LQ+VSPKL A DLELAVPGTY KPVIRI+HF F VISSKQRPRRL+I GSD
Sbjct: 1918 KHLELQYVSPKLLDACDLELAVPGTYGHNKPVIRISHFHHTFEVISSKQRPRRLTIHGSD 1977
Query: 2096 GKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLG 2155
GKDYQY++KGHED+RQD VMQLFGL NTLL + E+F+R LNI++Y IPLSP SGLLG
Sbjct: 1978 GKDYQYVLKGHEDLRQDERVMQLFGLCNTLLTTDSETFKRRLNIERYTVIPLSPNSGLLG 2037
Query: 2156 WVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQD 2215
WVP+SDT H LI+E R + LN+EHR+MLQMAPD D+LTLLQK+EVF Y + NT G D
Sbjct: 2038 WVPHSDTLHFLIKEFRSKRNILLNLEHRMMLQMAPDCDSLTLLQKLEVFEYVMANTDGYD 2097
Query: 2216 LYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDF 2275
LY VLWLKSRSSE+WL+RRT+YT+SLAVMSMVGYILGLGDRHPSNLM+DR +GK++HIDF
Sbjct: 2098 LYHVLWLKSRSSEAWLDRRTSYTQSLAVMSMVGYILGLGDRHPSNLMMDRYSGKIIHIDF 2157
Query: 2276 GDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAIL 2335
GDCFE A+ REK+PEK+PFRLTRML AMEVSGI+G+++ITCE VM VLR N ESLMA+L
Sbjct: 2158 GDCFEVAMHREKFPEKIPFRLTRMLINAMEVSGIQGTYKITCELVMRVLRSNTESLMAVL 2217
Query: 2336 EAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDAAKMELQQ----KA 2391
EAF YDPLINW + + T + ++ E R A L + A
Sbjct: 2218 EAFVYDPLINWRL-MTKSSFGASTTLRPTSSSVEEKGRSYTHRARHADYAALSETNGVNA 2276
Query: 2392 EVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGWCSFW 2450
E N R+ VLKR+++KLTG DF ++L V QV+KLIQQAT+ ENLC+ Y+GWCSFW
Sbjct: 2277 EGLNERSIQVLKRVSNKLTGKDFDLKEQLPVKAQVEKLIQQATAPENLCRCYVGWCSFW 2335
>Hs4826730 [L] KOG0891 DNA-dependent protein kinase
Length = 2549
Score = 1736 bits (4495), Expect = 0.0
Identities = 985/2224 (44%), Positives = 1388/2224 (62%), Gaps = 140/2224 (6%)
Query: 327 LKDKFEEIYETTMRYRENKNIIIRKEIYAIIPVLAAFDPKLFTQ-KYLDSTMIHYLTLLK 385
+++KF+++ + ++ R +KN +I+ I ++P LAAF P FT +YL TM H L+ +K
Sbjct: 366 MEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVK 425
Query: 386 NMNSHPVTNSDKGPILISVGDIAYYVGPDIGPYLDAIVENLRDGLTTK---YKFRKDYEQ 442
++ ++G ++ V + YL +++ +R L K +K +K +
Sbjct: 426 K-------EKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQV 478
Query: 443 E--IFYCIGKLACAVRPLLAKYLNRGLLEYMLACPLSDHMQETLLIVCEKIPSLEGTINE 500
+ +F CI LA A+ P + + + LLE MLA LS + L + +IP L+ I +
Sbjct: 479 DATVFTCISMLARAMGPGIQQDIKE-LLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQD 537
Query: 501 KLLNIICLVLSGEKFRPPGSPTPMKPFSAETARNYRDQSLFKKTGEANNDIFDAVILTKA 560
LL ++ LVL + R PG P + A ++ D +T A
Sbjct: 538 GLLKMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEAS------------DVGSITLA 585
Query: 561 LRMLSDIKPK-YSLTEFIRRVIISYMEHDNLQVRKLAALTSCDLFVEDSI------CKQT 613
LR L + + +SLT+F+R ++ ++ ++R AA T C + SI
Sbjct: 586 LRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAART-CSRLLTPSIHLISGHAHVV 644
Query: 614 SLYALNVVSEVLSKLLTVAITDPVAEIRLEILRHLDTNFDPQLSQPDNTKLLFMALNDEV 673
S A+ VV++VLSKLL V ITDP +IR +L LD FD L+Q +N + LF+ALND+V
Sbjct: 645 SQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQV 704
Query: 674 FAIQMEAMRICGRLALVNPAYVIPSLRKTLIQLLTELKHSKLTRKKEECASLLCTLISSS 733
F I+ A+ GRL+ +NPA+V+P LRK LIQ+LTEL+HS + R KE+ A +L L+S++
Sbjct: 705 FEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNA 764
Query: 734 SDVTKPYLEPVIEILLPKSQDS----SSAVASTALKAIGELSVVGGEDMVPFLDELMPLI 789
+ +PY+EP+++ L+ K +D + V + L IGEL+ V G +M ++DEL +I
Sbjct: 765 PRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIII 824
Query: 790 IDTFQDQSNSFKRNAALKALGQLSASSGYVIDPLLDYPELLGVLLNILKSESSQNIRRET 849
+D QD S KR AL LGQL AS+GYV++P YP LL VLLN LK+E +Q RRE
Sbjct: 825 MDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREA 884
Query: 850 VRLIGILGALDPYKH----------REVERTSSTNITVEQNAPPIDVALLMQGMSPSN-E 898
+R++G+LGALDPYKH R+ S + Q++ + ++ M +
Sbjct: 885 IRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLD 944
Query: 899 EYYPTVVIGVLMKILKDPSLSIHHSTVIQAIMHIFQTMGLRCVIFLKQIIPGFILVMHTC 958
E+YP V + LM+I +D SLS HH+ V+QAI IF+++GL+CV FL Q++P F+ V+ C
Sbjct: 945 EFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVC 1004
Query: 959 PPSLLELYFQQLSVLISIVKQHIRLHVSEIVEVISEFFPI-VKLQLTIISVIESLSRALE 1017
++ E FQQL +L+S VK HIR ++ EIV ++ EF+ + +Q TII +IE + AL
Sbjct: 1005 DGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALG 1064
Query: 1018 GEFNPYLPNILSLFLDVLEKDQSNKKVVSIRILKSLVVFGPHLEEYAHLVLPTIIKLSEF 1077
GEF YLP ++ L V D S ++VSI++L ++ +FG +L++Y HL+LP I+KL +
Sbjct: 1065 GEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDA 1124
Query: 1078 SSGNL--KKAAIITIGRLSKNVNPLEMSSRIVQALVRVLNTSELEYVKATMNTXXXXXXX 1135
L +KAA+ T+ RL+++++ + +SRI+ +VR L+ S E M+T
Sbjct: 1125 PEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSP-ELRSTAMDTLSSLVFQ 1183
Query: 1136 XNIDFTVFIPVINKTLVKQNIQHTIYDRLVAKLLNNEPLPTKI---IIDKDFDLPNKEMD 1192
+ +FIP++NK LV+ I H YD L+ +++ L + +I + L + + D
Sbjct: 1184 LGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGD 1243
Query: 1193 DVKVAS------KKLPVNQLVLKNAWDCSQQRTKEDWQEWIRRLSISLLKESSSHALRAC 1246
+ KKL V+ + L+ AW +++ +K+DW EW+RRLS+ LLK+SSS +LR+C
Sbjct: 1244 ALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSC 1303
Query: 1247 SGLAGIYYPLARELFNASFASCWGELYTQYQEDLVQSLCSALSSPNNPPEIHQTLLNLVE 1306
LA Y P+AR+LFNA+F SCW EL Q++L++S+ AL+S + E+ QTLLNL E
Sbjct: 1304 WALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTS-QDIAEVTQTLLNLAE 1362
Query: 1307 FMEHDDK-PLPI----SISTLGEYAQRCHAYAKALHYKELEFIEEPTTSTIESLISINNQ 1361
FMEH DK PLP+ I LGE A +C AYAKALHYKELEF + PT + +ESLISINN+
Sbjct: 1363 FMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNK 1422
Query: 1362 LHQTDAAIGILKHAQQHH-DLQLKETWYEKLQRWDDALTAYNKREAAGEDSIEVTIGKMR 1420
L Q +AA G+L++A +H +L+++ TWYEKL W+DAL AY+K+ +D E+ +G+MR
Sbjct: 1423 LQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMR 1482
Query: 1421 SLHALGDWDQLSELAADKWASSKIDIKRXXXXXXXXXXXXXXQWDRIEQYIEVMKPQSPD 1480
L ALG+W QL + +KW + + QWD +E+Y ++ + D
Sbjct: 1483 CLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHD 1542
Query: 1481 KAFFAAVLCLHRNNFDKAQEQIFAARDLLVTEMSALVNESYNRAYGVVVRTQMVAELEEI 1540
AF+ AVL LH++ F AQ+ I ARDLL E++A+ ESY+RAYG +V M++ELEE+
Sbjct: 1543 GAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEV 1602
Query: 1541 IQYKNLPQGSDRRAMIRKTWNKRLLGCQKNVDVWQRILKVRSLVIKPKQDMKVWIKFANL 1600
IQYK +P+ RR +IR+ W +RL GCQ+ V+ WQ+IL VRSLV+ P +DM+ W+K+A+L
Sbjct: 1603 IQYKLVPE---RREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASL 1659
Query: 1601 CRKSGRLGLAQKTLNTLLEESSDPKNPNTARAP---PPVVYAQLKYMWATGSQKEALNHL 1657
C KSGRL LA KTL LL DP P P V YA +K MW + + +A H+
Sbjct: 1660 CGKSGRLALAHKTLVLLL--GVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHM 1717
Query: 1658 ISFTSRMAHDLGLDPSNMIAQSVPQNSSVSQHHIEDYTKLLARCFLKQGEWRVSLQPNWR 1717
F M Q+ ++ Q H ++ KL+ARCFLK GEW+++LQ
Sbjct: 1718 QHFVQTMQQ-----------QAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINE 1766
Query: 1718 LENPDAILGSYLLATHFDKSWYKAWHNWALANFEVTSSLTQR--IKDDKVLTLEDASTEF 1775
P +L Y AT D+SWYKAWH WA+ NFE + +D+K +
Sbjct: 1767 STIPK-VLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANI 1825
Query: 1776 TNGAVAGLGA--------------------NENFP-PELVQRHV------------VPAI 1802
TN A A EN P P +Q+ V VPA+
Sbjct: 1826 TNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAV 1885
Query: 1803 KGFFRSIALSQSSSLQDTLRLLTLWFKFGGIPEAAQAMHEGFGLIKIDNWLEVIPQLISR 1862
+GFFRSI+LS+ ++LQDTLR+LTLWF +G P+ +A+ EG I+ID WL+VIPQLI+R
Sbjct: 1886 QGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIAR 1945
Query: 1863 IHQPNQTVSRSLLSLLADLGKAHPQALVYPLTVAIKSDSVSRQRAALSIIDKMRMHSPKL 1922
I P V R + LL D+G+ HPQAL+YPLTVA KS + +R AA I+ M HS L
Sbjct: 1946 IDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTL 2005
Query: 1923 VDQAELVSDELIRVAVLWHELWYEGLEDASRQFFGEHNTEKMFATLEPLHEMLKRGPETL 1982
V QA +VS+ELIRVA+LWHE+W+EGLE+ASR +FGE N + MF LEPLH M++RGP+TL
Sbjct: 2006 VQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTL 2065
Query: 1983 REISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQTLDLQH 2042
+E SF ++GRDL +A EW Y ++ ++ +L QAWD+YY+VFRRIS++LPQL +L+LQ+
Sbjct: 2066 KETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQY 2125
Query: 2043 VSPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYI 2102
VSPKL +DLELAVPGTY +P+IRI P VI+SKQRPR+L++ GS+G ++ ++
Sbjct: 2126 VSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFL 2185
Query: 2103 VKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDT 2162
+KGHED+RQD VMQLFGLVNTLL N+P S +++L+IQ+Y IPLS SGL+GWVP+ DT
Sbjct: 2186 LKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDT 2245
Query: 2163 FHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWL 2222
H LIR++RE K+ LNIEHRIML+MAPDYD+LTL+QKVEVF +A++NT G DL K+LWL
Sbjct: 2246 LHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWL 2305
Query: 2223 KSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAA 2282
KS SSE W +RRT YTRSLAVMSMVGYILGLGDRHPSNLMLDR++GK++HIDFGDCFE A
Sbjct: 2306 KSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVA 2365
Query: 2283 ILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDP 2342
+ REK+PEK+PFRLTRMLT AMEV+G++G++RITC VM VLR++K+S+MA+LEAF YDP
Sbjct: 2366 MTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDP 2425
Query: 2343 LINWG-FDLPTQA-VMEQTGIDLPLANPSELLRKGVITVEDAAKM--------------E 2386
L+NW D T+ +T D A S + GV E A K +
Sbjct: 2426 LLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGD 2485
Query: 2387 LQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGW 2446
K E N +A ++ R+ DKLTG DF L VP QV+ LI+QATS ENLCQ YIGW
Sbjct: 2486 GLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGW 2545
Query: 2447 CSFW 2450
C FW
Sbjct: 2546 CPFW 2549
Score = 155 bits (391), Expect = 1e-36
Identities = 100/293 (34%), Positives = 152/293 (51%), Gaps = 24/293 (8%)
Query: 55 AALSDSNVENSVKAFNLIFTKLKSTSEMERTAASFELRSSLISLAREVSTEHFQRFSNDI 114
AA + + ++V + LKS +E R A+ EL+ + RE+S E RF + +
Sbjct: 8 AATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQL 67
Query: 115 NNKVFELIHGNDSNEKLGGVLAVDTLIDFYSRTDELPNQTSRLANYLRVLIPSNDIEVMR 174
N+ +FEL+ +D+NE+ GG+LA+ +LI + R ANYLR L+PSND VM
Sbjct: 68 NHHIFELVSSSDANERKGGILAIASLIGVEGGN---ATRIGRFANYLRNLLPSNDPVVME 124
Query: 175 AAAGTLGKLAVPGGTLTSEFVEFEVKTCIEWLTTSPENSSSNSKQEYRKHASLLIISAIA 234
A+ +G+LA+ G T T+E+VEFEVK +EWL + E R+HA++L++ +A
Sbjct: 125 MASKAIGRLAMAGDTFTAEYVEFEVKRALEWL--------GADRNEGRRHAAVLVLRELA 176
Query: 235 DNSPYLLYPFVNSILDNIWRALRDTKLVIRTDASVTLGKCLTIINNRDSSLTKK--WVQR 292
+ P + V DNI+ A+ D K IR A L CL + R+ +K W +
Sbjct: 177 ISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRH 236
Query: 293 LFNGCIYGLQ--------LNSTVSIHGTLLVYRQLV---SLEGGYLKDKFEEI 334
F G +N IHG LL+ +LV S+EG L+++ EEI
Sbjct: 237 TFEEAEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEI 289
>7297995 [L] KOG0891 DNA-dependent protein kinase
Length = 2470
Score = 1646 bits (4262), Expect = 0.0
Identities = 999/2523 (39%), Positives = 1455/2523 (57%), Gaps = 214/2523 (8%)
Query: 76 LKSTSEMERTAASFELRSSLISLAREVSTEHFQRFSNDINNKVFELIHGNDSNEKLGGVL 135
LKS + + A+ +L + + RE+S E +F ++ ++ +F +++ D NEK GG L
Sbjct: 14 LKSRNRNVQNKATQDLLFYVKTELREMSQEELAQFFDEFDHHIFTMVNATDINEKKGGAL 73
Query: 136 AVDTLIDFYSRTDELPNQTSRLANYLRVLIPSNDIEVMRAAAGTLGKLAVPGGTLTSEFV 195
A+ LI+ S N LR L+ ND+ VM AA +L KLA + ++
Sbjct: 74 AMKCLINCEGSLTARKG-ISPYLNRLRDLLLINDVSVMEIAARSLVKLANMPTSKGADSF 132
Query: 196 EFEVKTCIEWLTTSPENSSSNSKQEYRKHASLLIISAIADNSPYLLYPFVNSILDNIWRA 255
+F++K E L +QEYR+H+++ I+ +A P Y + + + I+ A
Sbjct: 133 DFDIKKAFEVL--------RGERQEYRRHSAVFILRELAIALPTYFYQHILTFFEVIFNA 184
Query: 256 LRDTKLVIRTDASVTLGKCLTIINNRDS---SLTKKWVQRLF---NGCIYGLQLNSTVS- 308
+ D K IR A L L + R+S S +W + + NG + L S+
Sbjct: 185 IFDPKPAIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEANGS-FNADLGSSKDQ 243
Query: 309 --------IHGTLLVYRQLVSLEGGYLKDKFEEIYETTMRYRENK------NIIIRKEIY 354
IHG L+V+ +L + ++ + + + NK + + ++
Sbjct: 244 KGVTRDDRIHGGLVVFNELFRCANATWERRYTSLKTLFPKTQHNKFLEASSSSSMGSQLN 303
Query: 355 AIIPVL-AAFDPKL-FTQKYL------------------------DSTMIHYLTLLKNMN 388
++P L F KL TQ +L + HY ++ N+
Sbjct: 304 TLVPRLKVPFIDKLGSTQTHLGEGEHHKGVAKFASHNVLESAYAQEILQEHYTSICDNVL 363
Query: 389 SHPVTNS---DKGPILISVGDIAYYVGPDIGPYLDAIVENLRDGLTTKYKFRKDYEQEIF 445
+ S + + I A+ + YL V +L L K K R +
Sbjct: 364 EQRTSKSPYVQQALLQILPRLAAFNRAVFVEKYLQTCVSHLMQILRGKEKDR----TVAY 419
Query: 446 YCIGKLACAVRPLLAKYLNRGLLEYMLACP------------------------------ 475
IG +A AV+ + +L+ + +A P
Sbjct: 420 ITIGYMAVAVQSAIEVHLSSIMTSVKVALPSKDLTSKRKVPVDPAVFACITLLAHAVKSE 479
Query: 476 LSDHMQETL-----------LIVC-----EKIPSLEGTINEKLLNIICLVLSGEKFRPPG 519
++D +++ L L VC E +P L+ I E L+ I+ VL + P
Sbjct: 480 IADDVKDILEQMFYTGLSPALTVCLRELSENVPQLKSAITEGLIGILSQVLMNKAAILPY 539
Query: 520 SPTPMKPFSAETARNYRDQSLFKKTGEANNDIFDAVILTKALRMLSDIKPKYSLTEFIRR 579
+ P D SL + N D V+ K L + + ++ +F++R
Sbjct: 540 TALPTIAI---------DGSLMQ-----NGDGATTVLALKTLGTFN--FEEQNMLDFVQR 583
Query: 580 VIISYMEHDNLQVRKLAALTSC----DLFVEDSICKQTSLYALNVVSEVLSKLLTVAITD 635
++ H+ ++R L A+ +C L V+ S + S + VS V+ +LL VAITD
Sbjct: 584 CADYFIVHEQQEIR-LEAVQTCTRLLKLAVQSSESMENSKTLSDTVSHVIERLLMVAITD 642
Query: 636 PVAEIRLEILRHLDTNFDPQLSQPDNTKLLFMALNDEVFAIQMEAMRICGRLALVNPAYV 695
+R+ ILR LD FD +L+QP++ LF+ L+DE+F I+ AM GRL+ +NPAYV
Sbjct: 643 MDCNVRIRILRSLDETFDGKLAQPESLNSLFITLHDEIFEIRELAMVTIGRLSSINPAYV 702
Query: 696 IPSLRKTLIQLLTELKHSKLTRKKEECASLLCTLISSSSDVTKPYLEPVIEILLPK--SQ 753
+P LR T+I+L+T+LK+S ++R KE+ A +L L+ S+ + Y+ P+++ L+PK
Sbjct: 703 MPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRLISSYMNPILKALVPKLHEP 762
Query: 754 DSSSAVASTALKAIGELSVV--GGEDMVPFLDELMPLIIDTFQDQSNSFKRNAALKALGQ 811
+S+ V L+ IG+L+ V G ++M + D+L+ ++++ D + KR AL LGQ
Sbjct: 763 ESNPGVILNVLRTIGDLAEVNGGSDEMELWADDLLSILLEMLGDAGSPDKRGVALWTLGQ 822
Query: 812 LSASSGYVIDPLLDYPELLGVLLNILKSESSQNIRRETVRLIGILGALDPYKH---REVE 868
L +++G V+ P YP L+ +L+N LK+E ++IRRET+R++G+LGA+DPYKH + +
Sbjct: 823 LISATGRVVTPYHKYPVLIDILINFLKTEQRRSIRRETIRVLGLLGAMDPYKHKMNKGLI 882
Query: 869 RTSSTNITVEQNAPPID------VALLMQGMSPSNEEYYPTVVIGVLMKILKDPSLSIHH 922
+ N+ + + +D A L+ M + +EYYP V I LM+IL+DP+LS H
Sbjct: 883 DSQKDNVLIAYSDGKVDESQDISTAELLVNMGNALDEYYPAVAIAALMRILRDPTLSTRH 942
Query: 923 STVIQAIMHIFQTMGLRCVIFLKQIIPGFILVMHTCPPSLLELYFQQLSVLISIVKQHIR 982
++V+QA+ IFQ++G++CV +L Q++P + + T +L E FQQL++L++ VK HI
Sbjct: 943 TSVVQAVTFIFQSLGIKCVPYLAQVLPNLLDNVRTADNNLREFLFQQLAILVAFVKLHII 1002
Query: 983 LHVSEIVEVISEFFPI-VKLQLTIISVIESLSRALEGEFNPYLPNILSLFLDVLEKDQSN 1041
++ +I ++I EF+ I LQ T+I++IE ++ AL EF YL ++ L VL+ D S
Sbjct: 1003 SYMGDIFKLIKEFWTINTPLQNTLINLIEQIAVALGCEFRDYLAELIPQILRVLQHDNSK 1062
Query: 1042 KKVVSIRILKSLVVFGPHLEEYAHLVLPTIIKL--SEFSSGNLKKAAIITIGRLSKNVNP 1099
++V+ R+L++L FG L Y L+LP I+KL S + + A+ TI L+ ++
Sbjct: 1063 DRMVTRRLLQALQKFGSTLGYYLPLILPPIVKLFDSPYVPQQVSMVALETINNLACQLDF 1122
Query: 1100 LEMSSRIVQALVRVLNTSELEYVKATMNTXXXXXXXXNIDFTVFIPVINKTLVKQNIQHT 1159
+ SSRI+ LVRVL+ +E E M T + VF+P++ +TL K I
Sbjct: 1123 TDFSSRIIHPLVRVLD-AEPELRDQAMTTLRSLAKQLGKKYLVFVPMVQRTLNKHRIVDP 1181
Query: 1160 IYDRLVAKLLNNEPLPTKIIIDKDFDLPNK------EMDDVKVASKKLPVNQLVLKNAWD 1213
Y+ L++K+ + L + P++ + D +K L V L+ AW
Sbjct: 1182 EYEELLSKIKSCSTLADSYGAGESELRPSRFKNNEPFVTDRNSNNKNLQVTTNELRTAWQ 1241
Query: 1214 CSQQRTKEDWQEWIRRLSISLLKESSSHALRACSGLAGIYYPLARELFNASFASCWGELY 1273
+++ +K+DW EW++RLSI LLKES SHALRAC LA Y L R+LFNA+F SCW EL
Sbjct: 1242 VTRRVSKDDWVEWLKRLSIGLLKESPSHALRACRSLAQEYDTLLRDLFNAAFISCWTELS 1301
Query: 1274 TQYQEDLVQSLCSALSSPNNPPEIHQTLLNLVEFMEHDDK-PLPISISTLGEYAQRCHAY 1332
+ +L QSL AL + PEI QT+LNL EFMEH D+ P+PI LG A C AY
Sbjct: 1302 PDLKNELTQSLIQAL-QVTDMPEITQTILNLAEFMEHCDRDPIPIETKLLGTRAMACRAY 1360
Query: 1333 AKALHYKELEFIEEPTTSTIESLISINNQLHQTDAAIGIL-KHAQQHHDLQLKETWYEKL 1391
AKAL YKE EF+ + ESLI INN+L Q +AA G+L ++ ++L ++ WYEKL
Sbjct: 1361 AKALRYKEEEFLLREDSQVFESLILINNKLQQREAAEGLLTRYRNAANELNVQGRWYEKL 1420
Query: 1392 QRWDDALTAYNKREAAGEDSIEVTIGKMRSLHALGDWDQLSELAADKWASSKIDIKRXXX 1451
WD+AL Y + +E +G MR L ALGDW +LS + +W + + K
Sbjct: 1421 HNWDEALEHYERNLKTDSSDLEARLGHMRCLEALGDWSELSNVTKHEWENFGTEAKSRAG 1480
Query: 1452 XXXXXXXXXXXQWDRIEQYIEVMKPQSPDKAFFAAVLCLHRNNFDKAQEQIFAARDLLVT 1511
W+ + +Y+ + + D +++ AVL +H ++F+ AQ I RDLL T
Sbjct: 1481 PLAAVAAWGLQDWEAMREYVRCIPEDTQDGSYYRAVLAVHHDDFETAQRLIDETRDLLDT 1540
Query: 1512 EMSALVNESYNRAYGVVVRTQMVAELEEIIQYKNLPQGSDRRAMIRKTWNKRLLGCQKNV 1571
E++++ ESY RAYG +V QM+AELEE+IQYK +P +RR ++ W KRL G Q+ V
Sbjct: 1541 ELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIP---ERREPLKTMWWKRLQGGQRLV 1597
Query: 1572 DVWQRILKVRSLVIKPKQDMKVWIKFANLCRKSGRLGLAQKTLNTLLEESSDPK-NPNTA 1630
+ W+RI++V SLV+KP +D+ W+K+A+LCRKSG L L+ KTL LL +DPK NPN
Sbjct: 1598 EDWRRIIQVHSLVVKPHEDIHTWLKYASLCRKSGSLHLSHKTLVMLL--GTDPKLNPNQP 1655
Query: 1631 RA--PPPVVYAQLKYMWATGSQKEALNHLISFTSRMAHDLGLDPSNMIAQSVPQNSSVSQ 1688
P V YA KYM A +EA L F S + +L P + Q
Sbjct: 1656 LPCNQPQVTYAYTKYMAANNQLQEAYEQLTHFVSTYSQELSCLPPEALKQ---------- 1705
Query: 1689 HHIEDYTKLLARCFLKQGEWRVSLQPNWRLENPDAILGS---YLLATHFDKSWYKAWHNW 1745
+L+ARC+L+ W+ LQ + R PDAI G+ + AT +D +WYKAWH W
Sbjct: 1706 ----QDQRLMARCYLRMATWQNKLQDSIR---PDAIQGALECFEKATSYDPNWYKAWHLW 1758
Query: 1746 ALANFEVTSSLTQRIKDDKVLTLEDASTEFTNGAVAGLGANENFPPEL--VQRHVVPAIK 1803
A NF+V + Q+ DK + GA G+ +L +QR+ VPA++
Sbjct: 1759 AYMNFKVVQA--QKSALDK---------QQPPGASMGMTMGSGLDSDLMIIQRYAVPAVQ 1807
Query: 1804 GFFRSIALSQSSSLQDTLRLLTLWFKFGGIPEAAQAMHEGFGLIKIDNWLEVIPQLISRI 1863
GFFRSI+L + +SLQDTLRLLTLWF +G E +A+ G LI+I+ WL+VIPQLI+RI
Sbjct: 1808 GFFRSISLIKGNSLQDTLRLLTLWFDYGNHAEVYEALLSGMKLIEINTWLQVIPQLIARI 1867
Query: 1864 HQPNQTVSRSLLSLLADLGKAHPQALVYPLTVAIKSDSVSRQRAALSIIDKMRMHSPKLV 1923
Q V + + LL D+GK HPQALVYPLTVA KS S++R+ AA I+D MR HSP LV
Sbjct: 1868 DTHRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSASLARRNAAFKILDSMRKHSPTLV 1927
Query: 1924 DQAELVSDELIRVAVLWHELWYEGLEDASRQFFGEHNTEKMFATLEPLHEMLKRGPETLR 1983
+QA + S+ELIRVA+LWHE W+EGLE+ASR +FG+ N + MF LEPLH ML+RGP+TL+
Sbjct: 1928 EQAVMCSEELIRVAILWHEQWHEGLEEASRLYFGDRNVKGMFEILEPLHAMLERGPQTLK 1987
Query: 1984 EISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQTLDLQHV 2043
E SF ++GR+L +A+EW YK + + +L++AWDIYY+VF++ISR+LPQL +L+L +V
Sbjct: 1988 ETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQKISRQLPQLTSLELPYV 2047
Query: 2044 SPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIV 2103
SPKL KDLELAVPG+Y+ G+ +IRI+ + VI+SKQRPR+L I+GS+GKDY Y++
Sbjct: 2048 SPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLL 2107
Query: 2104 KGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTF 2163
KGHED+RQD VMQLF LVNTLL ++P++F+R+L IQ+Y IPLS SGL+GWVP+ DT
Sbjct: 2108 KGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTL 2167
Query: 2164 HVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLK 2223
H LIR++R+ KVPLN EHR ML APDYD+LTL+QKVEVF +AL T+G DL K+LWLK
Sbjct: 2168 HTLIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLK 2227
Query: 2224 SRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAI 2283
S SSE W ERR YTRSLAVMSMVGYILGLGDRHPSNLMLDR++GK++HIDFGDCFE A+
Sbjct: 2228 SPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAM 2287
Query: 2284 LREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPL 2343
REK+PEK+PFRLTRML AMEV+GIEG++R TCE+VM+VLR NK+SLMA+LEAF YDPL
Sbjct: 2288 TREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPL 2347
Query: 2344 INWG-FDLPTQAVMEQTGIDLPLANPSELLRKGVI-TVEDAAKM--------ELQQ---- 2389
+NW D+ + G P ++ + +VED+ M LQQ
Sbjct: 2348 LNWRLLDVDKKGNDAVAGAGAPGGRGGSGMQDSLSNSVEDSLPMAKSKPYDPTLQQGGLH 2407
Query: 2390 --KAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGWC 2447
A+ N++A+ V+KR+ KLTG DF + ++ QV+ LIQQAT+ ENLCQ YIGWC
Sbjct: 2408 NNVADETNSKASQVIKRVKCKLTGTDFQTEKSVNEQSQVELLIQQATNNENLCQCYIGWC 2467
Query: 2448 SFW 2450
FW
Sbjct: 2468 PFW 2470
>At1g50030 [L] KOG0891 DNA-dependent protein kinase
Length = 2467
Score = 1520 bits (3935), Expect = 0.0
Identities = 961/2532 (37%), Positives = 1393/2532 (54%), Gaps = 306/2532 (12%)
Query: 87 ASFELRSSLISLAREVSTEHFQRFSNDINNKVFELIHGNDSNEKLGGVLAVDTLIDFYSR 146
A R + R++S E RF + +++ LI D E +G + A+D L +
Sbjct: 57 APLAFRKHVEEAVRDLSGEASSRFMEQLYDRIANLIESTDVAENMGALRAIDELTEI--G 114
Query: 147 TDELPNQTSRLANYLRVLIP-SNDIEVMRAAAGTLGKLAVPGGTLTSEFVEFEVKTCIEW 205
E + SR A Y+R + D E++ A+ LG LA GG +TS+ VEF++KT +W
Sbjct: 115 FGENATKVSRFAGYMRTVFELKRDPEILVLASRVLGHLARAGGAMTSDEVEFQMKTAFDW 174
Query: 206 LTTSPENSSSNSKQEYRKHASLLIISAIADNSPYLLYPFVNSILDNIWRALRDTKLVIRT 265
L + EYR+ A++LI+ +A+N+ + V +D IW ALRD +L +R
Sbjct: 175 LRVD--------RVEYRRFAAVLILKEMAENASTVFNVHVPEFVDAIWVALRDPQLQVRE 226
Query: 266 DASVTLGKCLTIINNRDSSLTKKWVQRLFNGCIYGLQLNSTV-SIHGTLLVYRQLVSLEG 324
A L CL +I R++ +W R+F GL N+ V SIHG+LL +L+ G
Sbjct: 227 RAVEALRACLRVIEKRETRWRVQWYYRMFEATQDGLGRNAPVHSIHGSLLAVGELLRNTG 286
Query: 325 GYLKDKFEEIYETTMRYRENKNIIIRKEIYAIIPVLAAFDPKLFTQKYLDSTMIHYLTLL 384
++ ++ E+ E +RY E+++ ++R I +++P +A H+L
Sbjct: 287 EFMMSRYREVAEIVLRYLEHRDRLVRLSITSLLPRIA-----------------HFL--- 326
Query: 385 KNMNSHPVTNSDKGPILISVGDIAYYVGPDIGPYLDAIVENLRDGLTTKYKFRKDYEQEI 444
+++ I++G++A + ++ YL I+ +LRD + + + E
Sbjct: 327 -----RDRIPAERASGFIALGEMAGALDGELIHYLPTIMSHLRDAIAPR---KGRPLLEA 378
Query: 445 FYCIGKLACAVRPLLAKYLNRGLLEYMLACPLSDHMQETLLIVCEKIPSLEGTINEKLLN 504
C+G +A A+ + ++ R LL+ M + LS + + L + IPSL T+ ++LL+
Sbjct: 379 VACVGNIAKAMGSTVETHV-RDLLDVMFSSSLSSTLVDALDQITISIPSLLPTVQDRLLD 437
Query: 505 IICLVLSGEKF---RPP-----GSPTPMKPFSAETARNYRDQSLFKKTGEANNDIFDAVI 556
I LVLS + +PP GS M P S++ + + + Q
Sbjct: 438 CISLVLSKSHYSQAKPPVTIVRGSTVGMAPQSSDPSCSAQVQL----------------- 480
Query: 557 LTKALRMLSDIKPK-YSLTEFIRRVIISYMEHDNLQVRKLAALTSCDLFVED-------- 607
AL+ L+ K + L EF R ++ Y++ ++ RK AAL C L
Sbjct: 481 ---ALQTLARFNFKGHDLLEFARESVVVYLDDEDAATRKDAALCCCRLIANSLSGITQFG 537
Query: 608 -SICKQTSLYALNVVSEVLSKLLTVAITDPVAEIRLEILRHLDTN--FDPQLSQPDNTKL 664
S + +V E++ KLL A+ D +R I L N FD L+Q D+
Sbjct: 538 SSRSTRAGGRRRRLVEEIVEKLLRTAVADADVTVRKSIFVALFGNQCFDDYLAQADSLTA 597
Query: 665 LFMALNDEVFAIQMEAMRICGRLALVNPAYVIPSLRKTLIQLLTELKHSKLTRKKEECAS 724
+F +LNDE ++ A+ + GRL+ NPAYV+P+LR+ LIQLLT L+ S + +EE A
Sbjct: 598 IFASLNDEDLDVREYAISVAGRLSEKNPAYVLPALRRHLIQLLTYLELSADNKCREESAK 657
Query: 725 LLCTLISSSSDVTKPYLEPVIEILLPKSQDSSSAVAST-----ALKAIGELSVVGGEDMV 779
LL L+ + + PY+ PV + L+ + + + A+ L +G+L+ VGG M
Sbjct: 658 LLGCLVRNCERLILPYVAPVQKALVARLSEGTGVNANNNIVTGVLVTVGDLARVGGLAMR 717
Query: 780 PFLDELMPLIIDTFQDQSNSFKRNAALKALGQLSASSGYVIDPLLDYPELLGVLLNILKS 839
++ ELMPLI++ D + KR A+ LGQ+ S+GYV+ P +YP LLG+LL +LK
Sbjct: 718 QYIPELMPLIVEALMDGAAVAKREVAVSTLGQVVQSTGYVVTPYKEYPLLLGLLLKLLKG 777
Query: 840 ESSQNIRRETVRLIGILGALDPYKHREVERTSSTNI------TVEQNAPPIDVALLMQGM 893
+ + RRE ++++GI+GALDP+ H+ +++ S + T + P + L +
Sbjct: 778 DLVWSTRREVLKVLGIMGALDPHVHKRNQQSLSGSHGEVPRGTGDSGQPIPSIDELPVEL 837
Query: 894 SPS---NEEYYPTVVIGVLMKILKDPSLSIHHSTVIQAIMHIFQTMGLRCVIFLKQIIPG 950
PS +E+YY TV I LM+IL+D SL +H V++++M IF++MGL CV +L +++P
Sbjct: 838 RPSFATSEDYYSTVAINSLMRILRDASLLSYHKRVVRSLMIIFKSMGLGCVPYLPKVLPE 897
Query: 951 FILVMHTCPPSLLELYFQQLSVLISIVKQHIRLHVSEIVEVISEFFPIVKL--------- 1001
+ T +L + L L+SIV+QHIR ++ E++ ++SE + L
Sbjct: 898 LFHTVRTSDENLKDFITWGLGTLVSIVRQHIRKYLPELLSLVSELWSSFTLPGPIRPSRG 957
Query: 1002 ----------QLT---IISVIESLSRALEGEFNPYLPNILSLFLDVL-EKDQSNKKVVSI 1047
LT ++ ++E L AL EF YLP IL F+ VL + ++ N
Sbjct: 958 LPISYGEYFASLTDNQVLHLLEHLCLALNDEFRTYLPVILPCFIQVLGDAERFNDYTYVP 1017
Query: 1048 RILKSLVVFGPHLEEYAHLVLPTIIKLSEFSSG-NLKKAAIITIGRLSKNVNPLEMSSRI 1106
IL +L VFG L+E+ HL+LP +I+L + + +++ AI T+ R+ V S +
Sbjct: 1018 DILHTLEVFGGTLDEHMHLLLPALIRLFKVDAPVAIRRDAIKTLTRVIPCVQVTGHISAL 1077
Query: 1107 VQALVRVLNTSELEYVKATMNTXXXXXXXXNIDFTVFIPVINKTLVKQNIQHTIYDRLVA 1166
V L VL+ E K ++ DFT+FI I+K L+K ++H ++ + A
Sbjct: 1078 VHHLKLVLDGKNDELRKDAVDALCCLAHALGEDFTIFIESIHKLLLKHRLRHKEFEEIHA 1137
Query: 1167 KLLNNEPL--------------PTKIIIDKDFDLPNKEMDDVKVAS-KKLPVNQLVLKNA 1211
+ EPL P ++I D + E+D + + + VN L+ A
Sbjct: 1138 RWRRREPLIVATTATQQLSRRLPVEVIRDPVIE---NEIDPFEEGTDRNHQVNDGRLRTA 1194
Query: 1212 WDCSQQRTKEDWQEWIRRLSISLLKESSSHALRACSGLAGIYYPLARELFNASFASCWGE 1271
+ SQ+ TKEDW+EW+R SI LLKES S ALR C+ LA + + RELF A F SCW +
Sbjct: 1195 GEASQRSTKEDWEEWMRHFSIELLKESPSPALRTCAKLAQLQPFVGRELFAAGFVSCWAQ 1254
Query: 1272 LYTQYQEDLVQSLCSALSSPNNPPEIHQTLLNLVEFMEHDDKPLPISISTLGEYAQRCHA 1331
L Q+ LV+SL A SSPN PPEI TLLNL EFMEHD+KPLPI I LG A++C
Sbjct: 1255 LNESSQKQLVRSLEMAFSSPNIPPEILATLLNLAEFMEHDEKPLPIDIRLLGALAEKCRV 1314
Query: 1332 YAKALHYKELEF-------IEEPTTSTIESLISINNQLHQTDAAIGILKHAQQHHDLQLK 1384
+AKALHYKE+EF ++ + +E+LI INNQLHQ +AA+GIL +AQQH D+QLK
Sbjct: 1315 FAKALHYKEMEFEGPRSKRMDANPVAVVEALIHINNQLHQHEAAVGILTYAQQHLDVQLK 1374
Query: 1385 ETW----------YEKLQRWDDALTAYNKREAAGEDS---IEVTIGKMRSLHALGDWDQL 1431
E+ YEKLQRWDDAL AY + + + +E T+G+MR L AL W++L
Sbjct: 1375 ESCGKALTVFVSRYEKLQRWDDALKAYTLKASQTTNPHLVLEATLGQMRCLAALARWEEL 1434
Query: 1432 SELAADKWASSKIDIKRXXXXXXXXXXXXXXQWDRIEQYIEVMKPQSPDK---------- 1481
+ L + W+ ++ + +WD++ +Y+ + K
Sbjct: 1435 NNLCKEYWSPAEPSARLEMAPMAAQAAWNMGEWDQMAEYVSRLDDGDETKLRGLASPVSS 1494
Query: 1482 -------AFFAAVLCLHRNNFDKAQEQIFAARDLLVTEMSALVNESYNRAYGVVVRTQMV 1534
FF AVL + R +D+A+E + AR L TE++ALV ESY RAY +VR Q +
Sbjct: 1495 GDGSSNGTFFRAVLLVRRAKYDEAREYVERARKCLATELAALVLESYERAYSNMVRVQQL 1554
Query: 1535 AELEEIIQYKNLPQGS----DRRAMIRKTWNKRLLGCQKNVDVWQRILKVRSLVIKPKQD 1590
+ELEE+I+Y LP G+ +RRA+IR W +R+ G ++NV+VWQ +L VR+LV+ P +D
Sbjct: 1555 SELEEVIEYYTLPVGNTIAEERRALIRNMWTQRIQGSKRNVEVWQALLAVRALVLPPTED 1614
Query: 1591 MKVWIKFANLCRKSGRLGLAQKTLNTLL--EESSDPKNPNTARAPPPVVYAQLKYMWATG 1648
++ W+KFA+LCRKSGR+ A+ TL LL + P+N PP V+ LKY W+ G
Sbjct: 1615 VETWLKFASLCRKSGRISQAKSTLLKLLPFDPEVSPENMQ-YHGPPQVMLGYLKYQWSLG 1673
Query: 1649 SQ---KEALNHLISFTSRMAHDLGLDPSNMIAQSVPQNSSVSQHHIEDYTKLLARCFLKQ 1705
+ KEA L T ++ + S+++A V + LLAR LK
Sbjct: 1674 EERKRKEAFTKLQILTRELS-SVPHSQSDILASMVSSKGA--------NVPLLARVNLKL 1724
Query: 1706 GEWRVSLQPNWRLENPDAILGSYLLATHFDKSWYKAWHNWALANFEVTSSLTQRIKDDKV 1765
G W+ +L + I ++ +T + W KAWH WAL N V S R
Sbjct: 1725 GTWQWALSSGLNDGSIQEIRDAFDKSTCYAPKWAKAWHTWALFNTAVMSHYISR------ 1778
Query: 1766 LTLEDASTEFTNGAVAGLGANENFPPELVQRHVVPAIKGFFRSIALSQSS-----SLQDT 1820
++ ++VV A+ G+F SIA + ++ SLQD
Sbjct: 1779 -------------------------GQIASQYVVSAVTGYFYSIACAANAKGVDDSLQDI 1813
Query: 1821 LRLLTLWFKFGGIPEAAQAMHEGFGLIKIDNWLEVIPQLISRIHQPNQTVSRSLLSLLAD 1880
LRLLTLWF G + A+ GF + I+ WL V+PQ+I+RIH N+ V + SLL
Sbjct: 1814 LRLLTLWFNHGATADVQTALKTGFSHVNINTWLVVLPQIIARIHSNNRAVRELIQSLLIR 1873
Query: 1881 LGKAHPQALVYPLTVAIKSDSVSRQRAALSIIDKMRMHSPKLVDQAELVSDELIRVAVLW 1940
+G+ HPQAL+YPL VA KS S R+ AA ++DK+R HS LVDQA+LVS ELIRVA+LW
Sbjct: 1874 IGENHPQALMYPLLVACKSISNLRRAAAQEVVDKVRQHSGALVDQAQLVSHELIRVAILW 1933
Query: 1941 HELWYEGLEDASRQFFGEHNTEKMFATLEPLHEML----KRGPETLREISFQNSFGRDLN 1996
HE+W+E LE+ASR +FGEHN E M LEPLH+ML K+ T++E +F ++ +L
Sbjct: 1934 HEMWHEALEEASRLYFGEHNIEGMLKVLEPLHDMLDEGVKKDSTTIQERAFIEAYRHELK 1993
Query: 1997 DAHEWVMNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQTLDLQHVSPKLAAAKDLELA 2056
+AHE NYK T L QAWD+YY+VF+RI ++L L TLDL+ VSP+L +DLELA
Sbjct: 1994 EAHECCCNYKITGKDAELTQAWDLYYHVFKRIDKQLASLTTLDLESVSPELLLCRDLELA 2053
Query: 2057 VPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVM 2116
VPGTY A PV+ I+ F VI+SKQRPR+L+I G+DG+DY +++KGHED+RQD VM
Sbjct: 2054 VPGTYRADAPVVTISSFSRQLVVITSKQRPRKLTIHGNDGEDYAFLLKGHEDLRQDERVM 2113
Query: 2117 QLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKV 2176
QLFGLVNTLL+N+ ++ ++ L+IQ+Y IPLSP SGL+GWVPN DT H LIREHR+A K+
Sbjct: 2114 QLFGLVNTLLENSRKTAEKDLSIQRYSVIPLSPNSGLIGWVPNCDTLHHLIREHRDARKI 2173
Query: 2177 PLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTT 2236
LN E++ ML APDYDNL L+ KVEVF YAL+NT+G DL
Sbjct: 2174 ILNQENKHMLSFAPDYDNLPLIAKVEVFEYALENTEGNDL-------------------- 2213
Query: 2237 YTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRL 2296
S VGYILGLGDRHPSNLML R +GK++HIDFGDCFEA++ REK+PEKVPFRL
Sbjct: 2214 --------SRVGYILGLGDRHPSNLMLHRYSGKILHIDFGDCFEASMNREKFPEKVPFRL 2265
Query: 2297 TRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGF----DLPT 2352
TRML AMEVSGIEG+FR TCENVM VLR NK+S+MA++EAF +DPLINW ++P
Sbjct: 2266 TRMLVKAMEVSGIEGNFRSTCENVMQVLRTNKDSVMAMMEAFVHDPLINWRLFNFNEVPQ 2325
Query: 2353 QAVM----------------EQTGIDLPLANPSELLRKGVITVEDAAKMELQQKAEVRNA 2396
A++ ++ D+ L P R+ I A M L EV N
Sbjct: 2326 LALLGNNNPNAPADVEPDEEDEDPADIDLPQPQRSTREKEIL--QAVNM-LGDANEVLNE 2382
Query: 2397 RATLVLKRIADKLTGNDFPR----------------------YQELSVPDQVDKLIQQAT 2434
RA +V+ R++ KLTG DF LSV QV KLI QAT
Sbjct: 2383 RAVVVMARMSHKLTGRDFSSSAIPSNPIADHNNLLGGDSHEVEHGLSVKVQVQKLINQAT 2442
Query: 2435 SVENLCQHYIGW 2446
S ENLCQ+Y+G+
Sbjct: 2443 SHENLCQNYVGY 2454
>CE28813 [L] KOG0891 DNA-dependent protein kinase
Length = 687
Score = 608 bits (1567), Expect = e-173
Identities = 317/675 (46%), Positives = 454/675 (66%), Gaps = 36/675 (5%)
Query: 1792 ELVQRHVVPAIKGFFRSIALSQSSSLQDTLRLLTLWFKFGGIPEAAQ--AMHEGFGLIKI 1849
+L +H A++ F +++ S S L+DTLRL+ LWF G + A+ E + +
Sbjct: 33 KLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPV 92
Query: 1850 DNWLEVIPQLISRIHQPNQTVSRSL-LSLLADLGKAHPQALVYPLTVAIKSDSVSRQRAA 1908
WLE IPQL++R+ P+ S L L +L ++ + PQA++Y LTVA +S V R + A
Sbjct: 93 TTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNA 152
Query: 1909 LSIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQFFG----EHNTEKM 1964
++++KM + KLV +A LV++EL+R A+LWHE W++ L+DASR +F ++N + M
Sbjct: 153 GTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAM 212
Query: 1965 FATLEPLHEMLKRG-PETLREISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYN 2023
F L +++++++G P T++E SFQ ++ DL +A +V ++ + ++ +LNQAW+IY +
Sbjct: 213 FDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCS 272
Query: 2024 VFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSK 2083
VF+++ +L L +LDL +VSP L +AKDLEL VPGTY P++ I F VI+SK
Sbjct: 273 VFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSK 332
Query: 2084 QRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYP 2143
QRPR++ I+GS+G DYQ+++KGHED RQD VMQLFGLVNTLL NN E+ +R+L IQ+Y
Sbjct: 333 QRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYS 392
Query: 2144 AIPLSPKSGLLGWVPNSDTFHVLIREHREA-SKVPLNIEHRIMLQMAPDYDNLTLLQKVE 2202
+ LS SGL+GWVPN DT H L++E+RE +K+PL+IEH+ + +++ + ++LTL+QK++
Sbjct: 393 IVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQ 452
Query: 2203 VFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLM 2262
+F AL T+G+DL VLWLKS SSE W +RRT YTRS+A MSMVGYILGLGDRHPSNLM
Sbjct: 453 LFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLM 512
Query: 2263 LDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMM 2322
LDR+TGKVVHIDFGDCFE A+LREK+PE+VPFRLTRML AMEV+G++G + T E V+
Sbjct: 513 LDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLK 572
Query: 2323 VLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDA 2382
+LR N+ESL+A+LEAF YDP+INW E ++K T +D
Sbjct: 573 MLRTNQESLLAVLEAFVYDPVINWRL--------------------VEGMKKDPKTRKDT 612
Query: 2383 AKMELQQKAEVRNARAT-LVLKRIADKLTGNDFPRY------QELSVPDQVDKLIQQATS 2435
+ A + ++ T +++ I KL G +F + L V +Q+ L +QATS
Sbjct: 613 GGRQNMAGAVLPSSSTTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATS 672
Query: 2436 VENLCQHYIGWCSFW 2450
NLCQ YIGWC FW
Sbjct: 673 PLNLCQSYIGWCPFW 687
>CE07705 [L] KOG0891 DNA-dependent protein kinase
Length = 2697
Score = 608 bits (1567), Expect = e-173
Identities = 317/675 (46%), Positives = 454/675 (66%), Gaps = 36/675 (5%)
Query: 1792 ELVQRHVVPAIKGFFRSIALSQSSSLQDTLRLLTLWFKFGGIPEAAQ--AMHEGFGLIKI 1849
+L +H A++ F +++ S S L+DTLRL+ LWF G + A+ E + +
Sbjct: 2043 KLYLKHAAHAVRCFAKALMCSPGSRLEDTLRLMQLWFDHGDDKDQDVYFALTETIFDLPV 2102
Query: 1850 DNWLEVIPQLISRIHQPNQTVSRSL-LSLLADLGKAHPQALVYPLTVAIKSDSVSRQRAA 1908
WLE IPQL++R+ P+ S L L +L ++ + PQA++Y LTVA +S V R + A
Sbjct: 2103 TTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNA 2162
Query: 1909 LSIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQFFG----EHNTEKM 1964
++++KM + KLV +A LV++EL+R A+LWHE W++ L+DASR +F ++N + M
Sbjct: 2163 GTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHRRLQDNNVQAM 2222
Query: 1965 FATLEPLHEMLKRG-PETLREISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYN 2023
F L +++++++G P T++E SFQ ++ DL +A +V ++ + ++ +LNQAW+IY +
Sbjct: 2223 FDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAFESSGNVKDLNQAWEIYCS 2282
Query: 2024 VFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSK 2083
VF+++ +L L +LDL +VSP L +AKDLEL VPGTY P++ I F VI+SK
Sbjct: 2283 VFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSK 2342
Query: 2084 QRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYP 2143
QRPR++ I+GS+G DYQ+++KGHED RQD VMQLFGLVNTLL NN E+ +R+L IQ+Y
Sbjct: 2343 QRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYS 2402
Query: 2144 AIPLSPKSGLLGWVPNSDTFHVLIREHREA-SKVPLNIEHRIMLQMAPDYDNLTLLQKVE 2202
+ LS SGL+GWVPN DT H L++E+RE +K+PL+IEH+ + +++ + ++LTL+QK++
Sbjct: 2403 IVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQ 2462
Query: 2203 VFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLM 2262
+F AL T+G+DL VLWLKS SSE W +RRT YTRS+A MSMVGYILGLGDRHPSNLM
Sbjct: 2463 LFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLM 2522
Query: 2263 LDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMM 2322
LDR+TGKVVHIDFGDCFE A+LREK+PE+VPFRLTRML AMEV+G++G + T E V+
Sbjct: 2523 LDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLK 2582
Query: 2323 VLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDA 2382
+LR N+ESL+A+LEAF YDP+INW E ++K T +D
Sbjct: 2583 MLRTNQESLLAVLEAFVYDPVINWRL--------------------VEGMKKDPKTRKDT 2622
Query: 2383 AKMELQQKAEVRNARAT-LVLKRIADKLTGNDFPRY------QELSVPDQVDKLIQQATS 2435
+ A + ++ T +++ I KL G +F + L V +Q+ L +QATS
Sbjct: 2623 GGRQNMAGAVLPSSSTTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLTEQATS 2682
Query: 2436 VENLCQHYIGWCSFW 2450
NLCQ YIGWC FW
Sbjct: 2683 PLNLCQSYIGWCPFW 2697
Score = 308 bits (789), Expect = 7e-83
Identities = 345/1496 (23%), Positives = 639/1496 (42%), Gaps = 273/1496 (18%)
Query: 465 RGLLEYMLACPLSDHMQETLLIVCEKIPSLEGTINEKLLNIICLVLSGEKFRPPGSPTPM 524
+ ++ ++ LS + L ++ +IP L + + ++ + L+G P P
Sbjct: 501 KAIIPQLMDITLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYQTLTGSLIPPKSEPI-- 558
Query: 525 KPFSAETARNYRDQSLFKKTGEANNDIFDAVILTKALRMLSDIK-PKYSLTEFIRRVIIS 583
R +++ +K A D + + A+ +L + + +L ++ V
Sbjct: 559 -------GRPASPKAILQK---AETDPKELQRIVLAVDVLGEFYFSRGALQRIMQYVADY 608
Query: 584 YMEHDNLQVRKLAALTSCDLFV-------EDSICKQTSLYALNVVSEVLSKLLTVAITDP 636
Y+ DN+++R A + C++ V + + K+ SL L + VL + +V + D
Sbjct: 609 YLTADNVEIRLAAVSSCCEMVVPFVGVYKKVTSDKRNSL--LQTIYGVLRAVCSVIVNDQ 666
Query: 637 VAEIRLEILR---HLDTNFDPQLSQPDNTKLLFMALNDEVFAIQMEAMRICGRL-----A 688
+R++++ + F L+QP+ ++ FMAL+DE +Q + + GRL A
Sbjct: 667 DVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEMQQACVTLLGRLAELNPA 726
Query: 689 LV-------------------------------------NPAYVIPSLRKTLIQLLTEL- 710
LV +P ++ P + +I ++ +L
Sbjct: 727 LVLPRLRLMLLETLSQMQQSGQARLEQHSAKMIAQLAKQSPKFMRPYVGSLMIAMIPKLR 786
Query: 711 ---KHSKLTRKKEECASLLCTLISSSSDVTKPYLEPVIEILLPKSQDSSSA-VASTALKA 766
K++++T + S + + +++ K L+P+ E L DSSS AL+A
Sbjct: 787 NDQKYAEVTAQVLNAVSEIAVI--GGAEIVKN-LKPLFEKLTHMINDSSSLHKREAALRA 843
Query: 767 IGELS------VVGGEDMVPFLDELMPLI---------------------IDTFQDQ--S 797
IG + V D LD+L+ ++ ID + + +
Sbjct: 844 IGGICRSTAYVVDPYRDYPSLLDDLLRILKTVMSNTMRREAIKTLGILGAIDPYTHKVFT 903
Query: 798 NSFKRNAALKALGQLSASSGYVIDPLLD---------------YPEL-LGVLLNILKSES 841
S + + A+ L S DP D YP + + L+ +++ E
Sbjct: 904 GSVQSSTAISTALSLPISETDSKDPRQDIIHWFNYEKCTLEEFYPAITIANLMLMMQDED 963
Query: 842 SQN---IRRETVRLIGILGALDP-YKHREVER--------TSSTN------ITVEQNAPP 883
SQ+ I + V + LG + P Y + + R T S+N ++Q A
Sbjct: 964 SQSYAEIAQAIVTIFRSLGDMAPLYTEQVIPRLIEVCRRATESSNRANLREFFLQQLAN- 1022
Query: 884 IDVALLMQGMSPSNEEYYPTVVIGVLMKILKDPSLSIHHSTVIQAIMHIFQTMGLRCVIF 943
VA++ + +P Y P + + +D S+ + VI+ + + +G +
Sbjct: 1023 -FVAIIRKHAAP----YMPAIFTIIADAWKEDISVKM---VVIEVLTDMGTAIGNDFSKY 1074
Query: 944 LKQIIPGFILVMHTCPPS---LLELYFQQLSVLISIVKQHIRLHVSEIVEVISEFFPIVK 1000
++IP + V+ T L + + L + QH+ L + ++ ++ +F +
Sbjct: 1075 TGELIPYLLTVLQTDKTKERVLTVKVMESIQKLTHCIVQHLHLVLPPLLIILDDFSLKLS 1134
Query: 1001 LQLTIISVIESLSRALEGEFNPYLPNILSLFLDVLEKDQSNKKVVS--IRILKSLVVFGP 1058
++ T +S + +++ ++ + Y P ++ + + + K++ I I+K L F
Sbjct: 1135 IRNTALSTVLHMTQQVD--VSAYAPRMMQSWHHNISTAEMRDKLLLLLIEIIKQLGKFFD 1192
Query: 1059 HLEEYAHLVLPTIIKLSEFSSGNLKKAAIITIGRLSKNVNPLEMSSRIVQALVRVLNTSE 1118
+ KL ++ NL K+ + + K +MS ++ + V +
Sbjct: 1193 IFKRGVDQ------KLRDY---NLDKS--VHYEQYRKLAQRAQMSRDVLTSSVFAGSNGN 1241
Query: 1119 LEY--VKATMNTXXXXXXXXN-IDFTVFIPVINKTLVKQNIQHTIYDRLVAKLLNNEPLP 1175
++Y +A M N + + I+ +Q+ + Y V + + +P
Sbjct: 1242 IQYSSTQAGMRGQANNVYANNDLHERLMNGSIDSGASRQDNRDDYYRYGVEE---KKEVP 1298
Query: 1176 TKIIIDKDFDLPNKEMDDVKVASKKLPVNQLVLKNAWDCSQQRTKEDWQEWIRRLSISLL 1235
+ P E+ V++ ++L N+ L W +K++W +W+ ++ I L
Sbjct: 1299 K---VAPTTARPTSELVTVQITKQRL--NKDALMPQWKNENLTSKDEWLQWLMKIRIGFL 1353
Query: 1236 KESSSHALRACSGLAGIYYPLARELFNASFASCWGELYTQYQEDLVQSLCSALSSPNNPP 1295
SS +LRA S L + LAR+LF A+F S W EL + Q DL L A+S+ P
Sbjct: 1354 TYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELDSDVQNDLTSCLLRAIST--GIP 1411
Query: 1296 EIHQTLLNLVEFMEHDDK-PLPISISTLGEYAQRCHAYAKALHYKELEFIEEP----TTS 1350
E+ QT+LNL EFM+H +K PLPIS LG +A++ A+AKA YKE+ +++ TT
Sbjct: 1412 ELIQTILNLAEFMDHSEKGPLPISHDVLGRWAEQTKAFAKACRYKEMSVLKKSGSMQTTF 1471
Query: 1351 T---------IESLISINNQLHQTDAAIGILKHAQQHH-DLQLKETWYEKLQRWDDALTA 1400
T +SLI+ N+L+ + A G++++A+++ + Q++ WYEKL W+ AL A
Sbjct: 1472 TRKVKLEPNDCQSLITYANKLNVQEEAAGVVRYAERNEMNFQMRGRWYEKLNEWEKALGA 1531
Query: 1401 YNKREAAGED---------------------SIEVTIGKMRSLHALGDWDQLSELAADKW 1439
Y E + E + +MR L ALG WD+L+ + W
Sbjct: 1532 YELEEKKKSSCPNLQVYDEKDHLMTPEEAATAEEARMHEMRCLEALGRWDELNSKSV-VW 1590
Query: 1440 AS-------------SKIDIKRXXXXXXXXXXXXXXQWDRIEQYIEVMKPQSPDKAFFAA 1486
A +K + W+R+ Y+ V+ + D A A
Sbjct: 1591 ADQRGNRNDSVRDEINKKQLDHKMAVIAARGAWAVDNWERMADYVSVISENTQDGAMLRA 1650
Query: 1487 VLCLHRNNFDKAQEQIFAARDLLVTEMSALVNESYNRAYGVVVRTQMVAELEEIIQYKNL 1546
V+ +H + KA I R+++ +E++A+ NESY RAY +V Q +AELEE I+YK
Sbjct: 1651 VVAVHNDENTKAMGLIEKVREMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTR 1710
Query: 1547 PQGSDRRAMIRKTWNKRLLGCQKNVDVWQRILKVRSLVIKPKQDMKVWIKFANLCRKSGR 1606
P +RR I W++RL GC++NV+ WQR++ +R LV+ P++ + +KF+++CRK G+
Sbjct: 1711 P---ERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEMHPLRVKFSSMCRKQGK 1767
Query: 1607 LGLAQKTLNTLLEESSDPKNPNTARAPPP-----VVYAQLKYMWATGSQKEALNHLISFT 1661
+++ L LL S P N + RA P +V A K ++ + EA+ L
Sbjct: 1768 NSMSRAVLRELL---SLPANSDLVRAKAPFDKPLLVLALAKQLYQDDHKDEAIRALEDLA 1824
Query: 1662 SRMAHDLGLDPSNMIAQSVPQNSSVSQHHIEDYTKLLARCFLKQGEW------------- 1708
+ + P + +P ++ ++ ++ A+ LK GEW
Sbjct: 1825 NHWNKRINPIPKATGRELIPPST-------KEPARICAKVLLKLGEWTELKSKTSNNMQV 1877
Query: 1709 ------RVSLQPNWRLE---NPDAI-----LGSYLLATHFDKSWYKAWHNWALANF 1750
R + P +R + P+ I + Y AT +D W+K WH A +F
Sbjct: 1878 GELSFVRQQVSPQYRTKESRTPETIAFENTINYYQQATQYDPGWHKVWHKLASTHF 1933
>Hs18765739 [L] KOG0891 DNA-dependent protein kinase
Length = 3657
Score = 223 bits (568), Expect = 3e-57
Identities = 154/513 (30%), Positives = 242/513 (47%), Gaps = 69/513 (13%)
Query: 1897 IKSDSVSRQRAALSIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWY----------- 1945
+ D Q I+DK+ +P +V Q +++ EL RV VLW ELW
Sbjct: 1915 LNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVL 1974
Query: 1946 ---EGLEDASRQFFGEHNTEK------------------MFATLEPLHEMLKRGPETLRE 1984
+ LED ++ + K +FA LE + + ET E
Sbjct: 1975 RRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFA-LEHVRSITAAPAETPHE 2033
Query: 1985 ISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQT--LDLQH 2042
FQ+++G + +A E K + +W + + + ++ + + L L+
Sbjct: 2034 KWFQDNYGDAIENALE---KLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEE 2090
Query: 2043 VSPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYI 2102
+SP LAA + E+A+PG A + + I T++ +K +P++L GSDGK Y Y+
Sbjct: 2091 ISPWLAAMTNTEIALPGEVSA-RDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYL 2149
Query: 2103 VKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDT 2162
KG ED+ D +MQ +VNT+ + + Y PL +SGL+ WV +
Sbjct: 2150 FKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATP 2209
Query: 2163 FHVLIR--EHREAS----------KVPLNI------EHRIMLQMAPDYDNLTLLQKVE-- 2202
L + + REA+ + P N ++ P + L V
Sbjct: 2210 LFGLYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRR 2269
Query: 2203 ---------VFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGL 2253
V ++ T L K LW + + W +Y RS AVMSMVGYI+GL
Sbjct: 2270 DWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGL 2329
Query: 2254 GDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSF 2313
GDRH N+++D TG+VVHID+ CFE + PEKVPFR+T+ + A+ V+G+EG F
Sbjct: 2330 GDRHLDNVLIDMTTGEVVHIDYNVCFEKG-KSLRVPEKVPFRMTQNIETALGVTGVEGVF 2388
Query: 2314 RITCENVMMVLRDNKESLMAILEAFAYDPLINW 2346
R++CE V+ ++R +E+L+ +LEAF YDPL++W
Sbjct: 2389 RLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDW 2421
>Hs14719394 [L] KOG0891 DNA-dependent protein kinase
Length = 3031
Score = 223 bits (568), Expect = 3e-57
Identities = 154/513 (30%), Positives = 242/513 (47%), Gaps = 69/513 (13%)
Query: 1897 IKSDSVSRQRAALSIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWY----------- 1945
+ D Q I+DK+ +P +V Q +++ EL RV VLW ELW
Sbjct: 1289 LNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVL 1348
Query: 1946 ---EGLEDASRQFFGEHNTEK------------------MFATLEPLHEMLKRGPETLRE 1984
+ LED ++ + K +FA LE + + ET E
Sbjct: 1349 RRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFA-LEHVRSITAAPAETPHE 1407
Query: 1985 ISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQT--LDLQH 2042
FQ+++G + +A E K + +W + + + ++ + + L L+
Sbjct: 1408 KWFQDNYGDAIENALE---KLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEE 1464
Query: 2043 VSPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYI 2102
+SP LAA + E+A+PG A + + I T++ +K +P++L GSDGK Y Y+
Sbjct: 1465 ISPWLAAMTNTEIALPGEVSA-RDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYL 1523
Query: 2103 VKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDT 2162
KG ED+ D +MQ +VNT+ + + Y PL +SGL+ WV +
Sbjct: 1524 FKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATP 1583
Query: 2163 FHVLIR--EHREAS----------KVPLNI------EHRIMLQMAPDYDNLTLLQKVE-- 2202
L + + REA+ + P N ++ P + L V
Sbjct: 1584 LFGLYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRR 1643
Query: 2203 ---------VFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGL 2253
V ++ T L K LW + + W +Y RS AVMSMVGYI+GL
Sbjct: 1644 DWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGL 1703
Query: 2254 GDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSF 2313
GDRH N+++D TG+VVHID+ CFE + PEKVPFR+T+ + A+ V+G+EG F
Sbjct: 1704 GDRHLDNVLIDMTTGEVVHIDYNVCFEKG-KSLRVPEKVPFRMTQNIETALGVTGVEGVF 1762
Query: 2314 RITCENVMMVLRDNKESLMAILEAFAYDPLINW 2346
R++CE V+ ++R +E+L+ +LEAF YDPL++W
Sbjct: 1763 RLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDW 1795
>CE27869 [L] KOG0891 DNA-dependent protein kinase
Length = 2327
Score = 215 bits (547), Expect = 8e-55
Identities = 166/604 (27%), Positives = 270/604 (44%), Gaps = 82/604 (13%)
Query: 1820 TLRLLTLWFKFGGIPEAAQAMHEGFGLIKIDNWLEVIPQLISRIHQPNQTVSRSLLSLLA 1879
TLR+L L K G + +++G + W E++PQL +R+ P++ + ++L+ L++
Sbjct: 1463 TLRILELLVKHGDV--LIDVINDGLNKTNVHIWKEILPQLFARLSHPSEHIRKTLVDLIS 1520
Query: 1880 DLGKAHPQALVYPLTVAIKSDSV-------------SRQRAALSIID-KMRMHSPKLVDQ 1925
+ A P A+V+ + S S +R RA ++ M P LV
Sbjct: 1521 KICTAAPHAVVFQVVSGAASSSTDGEELEEQQNDDRNRVRACCEKLETNMSQSYPNLVKD 1580
Query: 1926 AELVSDELIRVAVLWHELWYEGL---------------------EDASRQFFGEHN---- 1960
EL R+ +L E W + E A N
Sbjct: 1581 VRQFVAELERINLLNEEKWSVVMGTMEHEMEKRLSLIRTENAKTESALHLTASVKNDIIV 1640
Query: 1961 ------TEKMFATLEPLHEM-LKRGPETLREISFQNSFGRDLNDAHEWVMNYKRTKDINN 2013
T ++F L+ L++ + P++ E F +F L +A + + T +
Sbjct: 1641 KRTQLLTRQIFDVLDELYQQTVIEPPKSKNEEEFVTAFAEVLTNAFQESRISRTTSPEKS 1700
Query: 2014 LNQAWDIYYNVFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAG-KPVIRITH 2072
++ N R S+K +QT + + +SP LA+ + + +PG V+ I+
Sbjct: 1701 WIPFKNLIANFVHRNSKK--GMQTFETEDISPYLASLSNSCVPMPGQESVEFDRVVSISR 1758
Query: 2073 FEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPES 2132
T++ +K RP++L GSDGK ++ KG ED+ D VMQ L N +LQ
Sbjct: 1759 VARQVTILPTKTRPKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGKGK 1818
Query: 2133 FQRHLNIQQ---YPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKV------------- 2176
++ + Q Y IPL P+SGL+ WV + + R+ + K
Sbjct: 1819 HRQSVAAYQAHHYAVIPLGPRSGLIKWVEGATPMFHIYRKWQMKEKALKQATKKNGETVP 1878
Query: 2177 ----PLNI----------EHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWL 2222
P N+ +H+I + D EVF T + + LW+
Sbjct: 1879 EIERPSNMYHNMIRLAFADHKIDSSITSDRSKWPAEILEEVFESLTAKTPTDLISRELWM 1938
Query: 2223 KSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAA 2282
++ + +W Y+RSLAVMSMVG +LGLGDRH NL++D G VVHID+ CF+
Sbjct: 1939 RANDATTWWSVTKRYSRSLAVMSMVGSVLGLGDRHLDNLLVDLKWGHVVHIDYNICFDKG 1998
Query: 2283 ILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDP 2342
+ PE VPFRLTR + +A+ S + G+FR +C +V+ LR + L +L+AF +DP
Sbjct: 1999 -KNLRIPETVPFRLTRNMRHALGPSEMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDP 2057
Query: 2343 LINW 2346
L++W
Sbjct: 2058 LVDW 2061
>Hs20336203 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telomere length
regulation and DNA repair
Length = 3056
Score = 203 bits (517), Expect = 2e-51
Identities = 137/406 (33%), Positives = 209/406 (50%), Gaps = 32/406 (7%)
Query: 2053 LELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQD 2112
+E+ V T G ++ I F+ F + P+ + GSDGK+ + +VKG +D+RQD
Sbjct: 2667 MEIKVDHTGEYGN-LVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQD 2725
Query: 2113 NLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGW-----------VPNSD 2161
++ Q+F + NTLLQ N E+ +R L I Y +PLS +SG+L W V N D
Sbjct: 2726 AVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNED 2785
Query: 2162 TFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLW 2221
H + +R + ++M ++ +K EVF N Q +++
Sbjct: 2786 GAH---KRYRPNDFSAFQCQKKMMEVQKKSFE-----EKYEVFMDVCQNF--QPVFRYFC 2835
Query: 2222 L-KSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFE 2280
+ K W E+R YTRS+A S+VGYILGLGDRH N++++ + ++VHID G FE
Sbjct: 2836 MEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFE 2895
Query: 2281 AAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAY 2340
+ PE VPFRLTR + M ++G+EG FR CE M V+R+++E+L+ I+E Y
Sbjct: 2896 QGKILPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLY 2954
Query: 2341 DPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDAAKMELQQKAEVRNARATL 2400
DPL +W + ++Q D +P+ + + K L + N A
Sbjct: 2955 DPLFDWTMNPLKALYLQQRPEDETELHPT------LNADDQECKRNLSDIDQSFNKVAER 3008
Query: 2401 VLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGW 2446
VL R+ +KL G + LSV QV+ LIQQA +NL + + GW
Sbjct: 3009 VLMRLQEKLKGVE--EGTVLSVGGQVNLLIQQAIDPKNLSRLFPGW 3052
>Hs20336199 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telomere length
regulation and DNA repair
Length = 1708
Score = 203 bits (517), Expect = 2e-51
Identities = 137/406 (33%), Positives = 209/406 (50%), Gaps = 32/406 (7%)
Query: 2053 LELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQD 2112
+E+ V T G ++ I F+ F + P+ + GSDGK+ + +VKG +D+RQD
Sbjct: 1319 MEIKVDHTGEYGN-LVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQD 1377
Query: 2113 NLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGW-----------VPNSD 2161
++ Q+F + NTLLQ N E+ +R L I Y +PLS +SG+L W V N D
Sbjct: 1378 AVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNED 1437
Query: 2162 TFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLW 2221
H + +R + ++M ++ +K EVF N Q +++
Sbjct: 1438 GAH---KRYRPNDFSAFQCQKKMMEVQKKSFE-----EKYEVFMDVCQNF--QPVFRYFC 1487
Query: 2222 L-KSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFE 2280
+ K W E+R YTRS+A S+VGYILGLGDRH N++++ + ++VHID G FE
Sbjct: 1488 MEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFE 1547
Query: 2281 AAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAY 2340
+ PE VPFRLTR + M ++G+EG FR CE M V+R+++E+L+ I+E Y
Sbjct: 1548 QGKILPT-PETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLY 1606
Query: 2341 DPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDAAKMELQQKAEVRNARATL 2400
DPL +W + ++Q D +P+ + + K L + N A
Sbjct: 1607 DPLFDWTMNPLKALYLQQRPEDETELHPT------LNADDQECKRNLSDIDQSFNKVAER 1660
Query: 2401 VLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGW 2446
VL R+ +KL G + LSV QV+ LIQQA +NL + + GW
Sbjct: 1661 VLMRLQEKLKGVE--EGTVLSVGGQVNLLIQQAIDPKNLSRLFPGW 1704
>At3g48190 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telomere length
regulation and DNA repair
Length = 3856
Score = 198 bits (504), Expect = 8e-50
Identities = 151/459 (32%), Positives = 219/459 (46%), Gaps = 60/459 (13%)
Query: 2011 INNLNQAWDIYYNVFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAGKPVIRI 2070
I + Q DIY + +R+ + + L ++ + K LEL T A PV R
Sbjct: 3431 IRQMKQLVDIYIKLAELETRREDTNRKVALPR---EIRSVKQLELVPVVT--ATIPVDRS 3485
Query: 2071 THFE----PIF-------TVISSKQRPRRLSIKGSDGKDYQYIVK-GHEDIRQDNLVMQL 2118
+ P F TV++ P+ + GSDG+ Y+ + K G++D+RQD ++ Q
Sbjct: 3486 CQYNEGSFPFFRGLSDSVTVMNGINAPKVVECFGSDGQKYKQLAKSGNDDLRQDAVMEQF 3545
Query: 2119 FGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTF-HVLIREHREAS--- 2174
FGLVNT L NN ++++R L ++ Y IP +P +G+L WV + LI R
Sbjct: 3546 FGLVNTFLHNNRDTWKRRLAVRTYKVIPFTPSAGVLEWVDGTIPLGDYLIGSSRSEGAHG 3605
Query: 2175 -------KVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSS 2227
K P EH + A D K + F N + Y L K
Sbjct: 3606 RYGIGNWKYPKCREH---MSSAKD--------KRKAFVDVCTNFRPVMHYFFLE-KFLQP 3653
Query: 2228 ESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREK 2287
W +R YTRS+A SMVGYI+GLGDRH N+++D+ T +VVHID G FE ++ K
Sbjct: 3654 ADWFVKRLAYTRSVAASSMVGYIVGLGDRHAMNILIDQATAEVVHIDLGVAFEQGLML-K 3712
Query: 2288 YPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWG 2347
PE+VPFRLTR + M ++G+EG FR CE + V+R NKE+L+ I+E F +DPL W
Sbjct: 3713 TPERVPFRLTRDIIDGMGITGVEGVFRRCCEETLSVMRTNKEALLTIVEVFIHDPLYKWA 3772
Query: 2348 FDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIAD 2407
P +A+ Q + D +E Q+ N AT L R+
Sbjct: 3773 LS-PLKALQRQKETE----------------DYDGMNLEGLQEEFEGNKDATRALMRVKQ 3815
Query: 2408 KLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGW 2446
KL G + + S+ Q +LIQ A + L + GW
Sbjct: 3816 KLDG--YEGGEMRSIHGQAQQLIQDAIDTDRLSHMFPGW 3852
>Hs4502325 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2644
Score = 196 bits (499), Expect = 3e-49
Identities = 131/385 (34%), Positives = 195/385 (50%), Gaps = 39/385 (10%)
Query: 2070 ITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNN 2129
I F+ + +++S Q+P+++S+KGSDGK Y + K +D+R+D +M+ L+N L+ +
Sbjct: 2293 IAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD 2352
Query: 2130 PESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFH-VLIREHREASKVPLNIEHRIMLQM 2188
ES +R L+I+ Y IPL+ + G++ WV N+ +L + ++E E R M
Sbjct: 2353 AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC--M 2410
Query: 2189 APDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVG 2248
P + L +K++VF L ++ SW R+ Y RS AVMSMVG
Sbjct: 2411 LP--KSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVG 2468
Query: 2249 YILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSG 2308
YILGLGDRH N++ D +TG+ VH+DF F E PE VPFRLT + M G
Sbjct: 2469 YILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFE-VPEIVPFRLTHNMVNGMGPMG 2527
Query: 2309 IEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANP 2368
EG FR CE M ++RD +E LM++L+ F +DPL+ W + P
Sbjct: 2528 TEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW-------------------SKP 2568
Query: 2369 SELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQ----ELSVPD 2424
V+ +K L + EV N +A + I +L G R + LS+
Sbjct: 2569 ----------VKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEG 2618
Query: 2425 QVDKLIQQATSVENLCQHYIGWCSF 2449
V LIQ+AT LCQ Y+GW +
Sbjct: 2619 HVHYLIQEATDENLLCQMYLGWTPY 2643
>Hs22041606 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 1212
Score = 196 bits (499), Expect = 3e-49
Identities = 131/385 (34%), Positives = 195/385 (50%), Gaps = 39/385 (10%)
Query: 2070 ITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNN 2129
I F+ + +++S Q+P+++S+KGSDGK Y + K +D+R+D +M+ L+N L+ +
Sbjct: 861 IAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD 920
Query: 2130 PESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFH-VLIREHREASKVPLNIEHRIMLQM 2188
ES +R L+I+ Y IPL+ + G++ WV N+ +L + ++E E R M
Sbjct: 921 AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC--M 978
Query: 2189 APDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVG 2248
P + L +K++VF L ++ SW R+ Y RS AVMSMVG
Sbjct: 979 LP--KSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVG 1036
Query: 2249 YILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSG 2308
YILGLGDRH N++ D +TG+ VH+DF F E PE VPFRLT + M G
Sbjct: 1037 YILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFE-VPEIVPFRLTHNMVNGMGPMG 1095
Query: 2309 IEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANP 2368
EG FR CE M ++RD +E LM++L+ F +DPL+ W + P
Sbjct: 1096 TEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW-------------------SKP 1136
Query: 2369 SELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQ----ELSVPD 2424
V+ +K L + EV N +A + I +L G R + LS+
Sbjct: 1137 ----------VKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEG 1186
Query: 2425 QVDKLIQQATSVENLCQHYIGWCSF 2449
V LIQ+AT LCQ Y+GW +
Sbjct: 1187 HVHYLIQEATDENLLCQMYLGWTPY 1211
>7293222 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2354
Score = 196 bits (498), Expect = 4e-49
Identities = 135/388 (34%), Positives = 199/388 (50%), Gaps = 56/388 (14%)
Query: 2068 IRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQ 2127
I I+ F+ ++ S +P++L+I+ SDGKDY +VK +D+R+D +M+ GLV L
Sbjct: 2016 IYISGFQESVLILRSAAKPKKLTIRCSDGKDYDVLVKPKDDLRRDARLMEFNGLVKRYLH 2075
Query: 2128 NNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQ 2187
+ + QR L+I+ Y +P + + GL+ W+PN ++ + ++ ++ ++
Sbjct: 2076 QDAPARQRRLHIRTYAVLPFNEECGLVEWLPNLASYRSICMNLYAQRRLVMS-TRQLQSL 2134
Query: 2188 MAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSR--SSESWLERRTTYTRSLAVMS 2245
P ++++ +K EVFT L + WL+ R + SW E R TY R++AVMS
Sbjct: 2135 AVPLHESIE--RKREVFTKQLVPAHPPVFQE--WLRQRFATPHSWYEARNTYIRTVAVMS 2190
Query: 2246 MVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAME 2305
MVGYILGLGDRH N++ G VH+DF F L YPE VPFRLT + AM
Sbjct: 2191 MVGYILGLGDRHGENILFAEGNGDAVHVDFNCLFNQGELL-PYPEVVPFRLTHNMIVAMG 2249
Query: 2306 VSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPL 2365
G+EGSFR CE + +L+ ++LM+IL F YD V QT
Sbjct: 2250 PLGVEGSFRKCCEITLRLLKQESKTLMSILRPFVYD-------------VGAQT------ 2290
Query: 2366 ANPSELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVP-- 2423
RKG T A+ T ++RIAD+L G+ R Q S+P
Sbjct: 2291 -------RKGAAT-----------------AKITKDVQRIADRLQGH-VKRQQANSIPLS 2325
Query: 2424 --DQVDKLIQQATSVENLCQHYIGWCSF 2449
QV+ LI +AT V+NL YIGW +F
Sbjct: 2326 TEGQVNFLINEATKVDNLASMYIGWGAF 2353
>7290761 [L] KOG0891 DNA-dependent protein kinase
Length = 2162
Score = 189 bits (481), Expect = 4e-47
Identities = 152/566 (26%), Positives = 257/566 (44%), Gaps = 79/566 (13%)
Query: 1811 LSQSSSLQDTLRLLTLWFKFG-GIPEAAQAMHEGFGLIKIDNWLEVIPQLISRIHQPNQT 1869
+ S+ + TLRLL L K G+ E + +G I W +IPQL SR++
Sbjct: 1606 VDDSNLVTTTLRLLRLIVKHASGLQEV---LEQGLHTTPIAPWKVIIPQLFSRLNHHEPY 1662
Query: 1870 VSRSLLSLLADLGKAHPQALVYPLTVAI---KSDSVSRQRAALS----------IIDKMR 1916
V +S+ LL L K+ PQ +++P V + D+ + A ++ ++
Sbjct: 1663 VRKSVCDLLCRLAKSRPQLVIFPAVVGANREQQDATAPPATARPTTEDACCYGYLLGELS 1722
Query: 1917 MHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQFF----------------GEHN 1960
+P+ V +L+ EL RV +LW E W L + G++N
Sbjct: 1723 KQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVSRVSALATDFRPDDHEGKNN 1782
Query: 1961 T-----EKMFATLEPLHEMLKRGPETLREISFQNSFGRDLNDAHEWVMNYKRTKDINNLN 2015
++ A LE L + R PET E SF+ F + + + + + + + L
Sbjct: 1783 RFNVWRPQLLADLEALVAVTSRPPETTYERSFRKRFDAPIRLTVDALRHRRYPEAWDKLK 1842
Query: 2016 QAWDIYYNVFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAGKP--VIRITHF 2073
Q + I + R S TL +Q +SP L + +++PG G + I
Sbjct: 1843 QLYHILQSNMIRGSGS-----TLKMQSISPVLCGIGRMRISMPGLDAHGPDGDQVYIESV 1897
Query: 2074 EPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPES- 2132
E V+ +K +P++++ GS+G+ Y ++ KG ED+ D +MQ + N ++ ++
Sbjct: 1898 ESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRSDAP 1957
Query: 2133 ----FQRHLNIQQYPAIPLSPKSGLLGWVPN-SDTFHVLIREHREASKVPLNIEHRIMLQ 2187
++ H Y IPL P+SGL+ WV + F + + + S+V N +
Sbjct: 1958 GNGCYRAH----HYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQVAGNAGAGAVAN 2013
Query: 2188 MAPDYDNL------TLLQK-------------VEVFTYALD----NTKGQDLYKVLWLKS 2224
+ + +L LL K + V LD T L + LW ++
Sbjct: 2014 VPRRFTDLFYNKLSPLLAKHNMQVSDPRRQWPISVLLQVLDELSQETPNDLLARELWCQA 2073
Query: 2225 RSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAIL 2284
++ W + + R ++VMSM+GY++GLGDRH N++++ +G +VHID+ CFE
Sbjct: 2074 GNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKG-R 2132
Query: 2285 REKYPEKVPFRLTRMLTYAMEVSGIE 2310
+ PEKVPFRLT+ L AM ++GIE
Sbjct: 2133 TLRIPEKVPFRLTQNLVQAMGITGIE 2158
>SPBC216.05 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2386
Score = 189 bits (480), Expect = 5e-47
Identities = 121/414 (29%), Positives = 209/414 (50%), Gaps = 71/414 (17%)
Query: 2050 AKDLELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDI 2109
AKD A + +P + FE +++S Q+PR++ ++G+DG Y ++ K +D+
Sbjct: 2031 AKDANRASHYPFPKTQPTL--LKFEDEVDIMNSLQKPRKVYVRGTDGNLYPFLCKPKDDL 2088
Query: 2110 RQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIRE 2169
R+D +M+ L+ +L+ + E+ +R+L I+ Y IPL+ + G + WV ++ F ++ +
Sbjct: 2089 RKDARLMEFNNLICKILRKDQEANRRNLCIRTYVVIPLNEECGFIEWVNHTRPFREILLK 2148
Query: 2170 HREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLY--KVL------- 2220
+P++ + ++ D D +AL + D++ K+L
Sbjct: 2149 SYRQKNIPISYQ-----EIKVDLD------------FALRSPNPGDIFEKKILPKFPPVF 2191
Query: 2221 --WLKSRSSE--SWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFG 2276
W E +W+ R Y R+LAVMS+VGY+LGLGDRH N++ D TG+ +H+DF
Sbjct: 2192 YEWFVESFPEPNNWVTSRQNYCRTLAVMSIVGYVLGLGDRHGENILFDEFTGEAIHVDFN 2251
Query: 2277 DCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILE 2336
F+ + EK PEKVPFRLT + AM +G EG FR E M +LR N+++LM++LE
Sbjct: 2252 CLFDKGLTFEK-PEKVPFRLTHNMVDAMGPTGYEGGFRKASEITMRLLRSNQDTLMSVLE 2310
Query: 2337 AFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDAAKMELQQKAEVRNA 2396
+F +DPL+ W +++ P +E+L
Sbjct: 2311 SFLHDPLVEWN--------RKKSSSKYPNNEANEVL------------------------ 2338
Query: 2397 RATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGWCSFW 2450
++ K+ + G P LS+ Q+ +LI+ A + +NL + YIGW +++
Sbjct: 2339 --DIIRKKFQGFMPGETIP----LSIEGQIQELIKSAVNPKNLVEMYIGWAAYF 2386
>7299977 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telomere length
regulation and DNA repair
Length = 2429
Score = 184 bits (467), Expect = 2e-45
Identities = 125/366 (34%), Positives = 179/366 (48%), Gaps = 39/366 (10%)
Query: 2086 PRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAI 2145
P ++ SDGK +VKG +D+RQD ++ Q+FG+VN LL + E +R L ++ Y
Sbjct: 2094 PVKIMCVCSDGKIRAQLVKGKDDLRQDAVMQQVFGIVNELLNQDSEFIERKLKLRTYKVT 2153
Query: 2146 PLSPKSGLLGWVPNS-DTFHVLIREHREASKV---PLNIEHRIMLQMAPDYDNLTLLQKV 2201
PLS +SG+L W NS H L+ E + + P + + +++ D+ +
Sbjct: 2154 PLSMRSGILEWCTNSVPVGHYLVVEGKGGAHARYRPNDWNNNKCRKLSSDHLKSPKETRY 2213
Query: 2202 EVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNL 2261
++ +N K Y +L K W ERR YT S+A SMVGY+LGLGDRH N+
Sbjct: 2214 AIYKKICENIKPVFHYFLLE-KFPIPGVWFERRLAYTNSVATTSMVGYVLGLGDRHTQNI 2272
Query: 2262 MLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVM 2321
++D+ T +V+HIDFG FE + + PE VPFRLTR M + G +G F +CE M
Sbjct: 2273 LVDQQTAEVIHIDFGIAFEQGKI-QTTPETVPFRLTRDFVAPMGICGTKGVFAKSCEATM 2331
Query: 2322 MVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITVED 2381
+LR K ILE YDPL WG +L+K
Sbjct: 2332 HILRRYKSVFTTILEVLLYDPLFIWG-----------------------VLKK------- 2361
Query: 2382 AAKMELQQKAEVR-NARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLC 2440
K QQ E N A L + +KL G + + +V QV++LI +AT NLC
Sbjct: 2362 --KQSPQQSGEESVNLVAQRALLLVQNKLDGREAGTMGDSNVEAQVERLINEATLPSNLC 2419
Query: 2441 QHYIGW 2446
+ GW
Sbjct: 2420 MLFPGW 2425
>YBL088c [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telomere length
regulation and DNA repair
Length = 2787
Score = 175 bits (443), Expect = 9e-43
Identities = 117/367 (31%), Positives = 182/367 (48%), Gaps = 28/367 (7%)
Query: 2086 PRRLSIKGSDGKDYQYIVKG-HEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPA 2144
P+ ++ SDG + ++KG ++D+RQD ++ Q+F VN +LQN+ L I+ Y
Sbjct: 2447 PKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQVFQQVNKVLQNDKVLRNLDLGIRTYKV 2506
Query: 2145 IPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVF 2204
+PL PK+G++ +V NS + H ++ + K+ + + M + + ++++ +
Sbjct: 2507 VPLGPKAGIIEFVANSTSLHQILSKLHTNDKITFDQARKGMKAVQTKSNE----ERLKAY 2562
Query: 2205 TYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLD 2264
+ K Q L + W E + TYT+ +A S+VGYILGLGDRH +N++LD
Sbjct: 2563 LKITNEIKPQ-LRNFFFDSFPDPLDWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLD 2621
Query: 2265 RVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVL 2324
TG+ +HID G F+ L PE VPFRLTR + V+G++G FR +CE V VL
Sbjct: 2622 CSTGEPIHIDLGIAFDQGKLL-PIPELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVL 2680
Query: 2325 RDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELL-RKGVITVEDAA 2383
R + +M +L +DPL +W + P+ L + IT D
Sbjct: 2681 RKDYVKVMCVLNILKWDPLYSW--------------VMSPVKKYEHLFEEEHEITNFDNV 2726
Query: 2384 KMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHY 2443
+ N + LK + +KL GN LSV V LIQQAT NL Y
Sbjct: 2727 SKFISNNDRNENQESYRALKGVEEKLMGNG------LSVESSVQDLIQQATDPSNLSVIY 2780
Query: 2444 IGWCSFW 2450
+GW F+
Sbjct: 2781 MGWSPFY 2787
>At5g40820 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2810
Score = 174 bits (442), Expect = 1e-42
Identities = 116/371 (31%), Positives = 179/371 (47%), Gaps = 47/371 (12%)
Query: 2079 VISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLN 2138
++SS QRP+++ + G+DG +Y ++ K +D+R+D +M+ ++N LL PES +R L
Sbjct: 2373 ILSSLQRPKKIILLGNDGIEYPFLCKPKDDLRKDARMMEFTAMINRLLSKYPESRRRKLY 2432
Query: 2139 IQQYPAIPLSPKSGLLGWVPNSDTF-HVLIREHREASKVPLNIEHRIMLQMAPDYDNLTL 2197
I+ + PL+ GL+ WVP++ H+L + K + Q+ YD +
Sbjct: 2433 IRTFAVAPLTEDCGLVEWVPHTRGLRHILQDIYISCGKFD---RQKTNPQIKRIYDQCAV 2489
Query: 2198 LQKVEVFTYALDNTKGQDLYKVLWLKSRSSE--SWLERRTTYTRSLAVMSMVGYILGLGD 2255
++ E+ + +K W + SE +W R Y + AV SMVG+I+GLGD
Sbjct: 2490 KKEYEMLKTKILPMFPPVFHK--WFLTTFSEPAAWFRSRVAYAHTTAVWSMVGHIVGLGD 2547
Query: 2256 RHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRI 2315
RH N++ D +G VH+DF F+ + EK PE VPFRLT+ + + ++G EG F
Sbjct: 2548 RHGENILFDSTSGDCVHVDFSCLFDKGLQLEK-PELVPFRLTQNMIDGLGITGYEGIFMR 2606
Query: 2316 TCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKG 2375
CE + VLR ++E+LM+ILE F +DPL+ W
Sbjct: 2607 VCEITLTVLRTHRETLMSILETFIHDPLVEW----------------------------- 2637
Query: 2376 VITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATS 2435
K EV+N A + I +L G L V Q +LI A S
Sbjct: 2638 -------TKSHKSSGVEVQNPHAQRAISSIEARLQG--VVVGVPLPVEGQARRLIADAVS 2688
Query: 2436 VENLCQHYIGW 2446
+ENL + YI W
Sbjct: 2689 LENLGKMYIWW 2699
>SPCC23B6.03c [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telomere length
regulation and DNA repair
Length = 2812
Score = 166 bits (419), Expect = 6e-40
Identities = 116/383 (30%), Positives = 199/383 (51%), Gaps = 20/383 (5%)
Query: 2070 ITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKG-HEDIRQDNLVMQLFGLVNTLLQN 2128
++ F+ S P+ ++ GS+G Y+ +VKG ++D+RQD ++ Q+F VN L++
Sbjct: 2446 VSSFDDTIHFASGINAPKVITCLGSNGHTYKQLVKGGNDDLRQDAVMEQVFEQVNGFLRS 2505
Query: 2129 NPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTF-HVLIREHREASKVPLNIEHRIMLQ 2187
++ QR+L+++ Y IPL+ K+G++ WV ++ L H+ ++ L
Sbjct: 2506 YRKTSQRNLSMRTYKVIPLALKTGVIEWVQDTIPLGEYLDSAHKVYHPKEWSLSTCRKLI 2565
Query: 2188 MAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSE-SWLERRTTYTRSLAVMSM 2246
++L KV Y L + +++ +L+S + W +T Y RS AV S+
Sbjct: 2566 AEKQMEDLETRLKV----YDLVCRHYRPVFRHFFLESYADPVQWFTTQTNYARSTAVASV 2621
Query: 2247 VGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEV 2306
+G++LGLGDRH N+++D+ +G+V+HID G FE + PE VPFRLTR + M +
Sbjct: 2622 LGHVLGLGDRHGQNILIDKTSGEVIHIDLGIAFEQG-KKLPVPECVPFRLTRDVVDGMGI 2680
Query: 2307 SGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLA 2366
+G+EG FR E + LR ++SL+++LE YDPL +W P + + +Q + L
Sbjct: 2681 TGVEGVFRRCMEFTLETLRREEDSLLSVLEVLRYDPLFSWLIS-PLRRMKKQK-MQLENF 2738
Query: 2367 NPSELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQV 2426
N E G IT + + ++Q+ + A + ++ KL+ LSV V
Sbjct: 2739 NQPE---SGNITTDASRDPKIQRNNVSGESEAERAILKVRQKLSST-------LSVEASV 2788
Query: 2427 DKLIQQATSVENLCQHYIGWCSF 2449
+LI+ A L + GW +F
Sbjct: 2789 GELIRIAQDPSYLALMFCGWSAF 2811
>YBR136w [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2368
Score = 162 bits (409), Expect = 8e-39
Identities = 109/332 (32%), Positives = 171/332 (50%), Gaps = 15/332 (4%)
Query: 2061 YHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFG 2120
Y +PV+ I F + V SS ++P++L+I GSDG Y + K ED+RQDN MQ
Sbjct: 2037 YQPFRPVVSIIRFGSSYKVFSSLKKPKQLNIIGSDGNIYGIMCK-KEDVRQDNQYMQFAT 2095
Query: 2121 LVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNI 2180
++ LL + S +R L I Y + L G+L VPN T ++ E+ K+ ++
Sbjct: 2096 TMDFLLSKDIASRKRSLGINIYSVLSLREDCGILEMVPNVVTLRSILSTKYESLKIKYSL 2155
Query: 2181 EHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRS 2240
+ + + + + K+E + +D LY+ +W R TY RS
Sbjct: 2156 K-----SLHDRWQHTAVDGKLEFYMEQVDKFP-PILYQWFLENFPDPINWFNARNTYARS 2209
Query: 2241 LAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRML 2300
AVM+MVG+ILGLGDRH N++LD TGKV+H+DF DC R PE VPFRLT L
Sbjct: 2210 YAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDF-DCLFEKGKRLPVPEIVPFRLTPNL 2268
Query: 2301 TYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVME--- 2357
A+ + G EG+F+ + E + ++R N+ +LM ++E YD ++ + +
Sbjct: 2269 LDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETIMYDRNMDHSIQKALKVLRNKIR 2328
Query: 2358 ----QTGIDLPLANPSELLRKGVITVEDAAKM 2385
Q G+ L +A +E L + + ++ +KM
Sbjct: 2329 GIDPQDGLVLSVAGQTETLIQEATSEDNLSKM 2360
>ECU02g1130 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 1935
Score = 140 bits (353), Expect = 3e-32
Identities = 106/388 (27%), Positives = 169/388 (43%), Gaps = 100/388 (25%)
Query: 2079 VISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLN 2138
V +S QRP+R+ GSDGK+Y ++ K +D+R+D+ M L ++N++L+ +S +++
Sbjct: 1630 VFNSLQRPKRICFVGSDGKNYYWLCKNQDDLRKDSRFMDLNLIINSILKK--QSSRKY-- 1685
Query: 2139 IQQYPAIPLSPKSGLLGWVPN-------SDTFH----VLIREHR----EASKVPLNIEHR 2183
I+ Y IP S +SG++ W+ DT++ + I E K+ + HR
Sbjct: 1686 IRTYAVIPFSHESGIIEWIGGLSSLKAICDTYYARDGISISETACRFVHNKKIGMREWHR 1745
Query: 2184 IMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRSSE--SWLERRTTYTRSL 2241
+ + P + LW SWL R YT++
Sbjct: 1746 VASKFHPKFH--------------------------LWFHDSFPHPFSWLVARNNYTQTY 1779
Query: 2242 AVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLT 2301
A+M++VG+ +GLGDRH N++ D TG VH+D +C + PE+VP+RLT+ +
Sbjct: 1780 AIMNIVGWFMGLGDRHAENILFDSNTGDTVHVDL-NCIFGKGKELQVPERVPYRLTQNIV 1838
Query: 2302 YAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGI 2361
A V G+EGS+ + + + NK L++ L +F YDPL W
Sbjct: 1839 DAFGVLGLEGSYNTSLCTTLDLFLKNKNILVSNLLSFVYDPLFEW--------------- 1883
Query: 2362 DLPLANPSELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELS 2421
R AT K I D + + +L
Sbjct: 1884 --------------------------------RRKSATTPKKIIEDL-----WHKMDDLD 1906
Query: 2422 VPDQVDKLIQQATSVENLCQHYIGWCSF 2449
+ D L ++AT+ ENLC YIGW F
Sbjct: 1907 ACSKCDVLNEEATNDENLCMMYIGWLPF 1934
>Hs13654237 [L] KOG0891 DNA-dependent protein kinase
Length = 4128
Score = 137 bits (344), Expect = 3e-31
Identities = 125/496 (25%), Positives = 225/496 (45%), Gaps = 41/496 (8%)
Query: 1885 HPQALVYPLTVA-----IKSDSVSRQRAALSIIDKMRMHSPKLVDQAELVSDELIRVAVL 1939
+PQA+VYP ++ K S + K ++ ++ D+L +L
Sbjct: 3525 YPQAIVYPFIISSESYSFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELL 3584
Query: 1940 WHELWYEGLEDASRQFFGEHNTEKMFATL-EPLHEMLKRGPETLREISFQNSFGRDLNDA 1998
+ + + + ++ + N EKM+ + L + G R F +FG++ D
Sbjct: 3585 FKDWSNDVRAELAKTPVNKKNIEKMYERMYAALGDPKAPGLGAFRR-KFIQTFGKEF-DK 3642
Query: 1999 HEWVMNYKRTK-DINNLNQAWDIYYNVFRRISRKLPQLQTLDLQHVSPKLAAAKDLELAV 2057
H K + +++ N ++ + S+ L+ K+ ++ EL +
Sbjct: 3643 HFGKGGSKLLRMKLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRN-ELEI 3701
Query: 2058 PGTYHA-GKPV----IRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQD 2112
PG Y GKP+ +RI F+ TV++S +RP+R+ I+G D +++ ++VKG ED+RQD
Sbjct: 3702 PGQYDGRGKPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQD 3761
Query: 2113 NLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLI----- 2167
V QLF ++N +L + QR L ++ Y +P++ + GL+ W+ N+ T L+
Sbjct: 3762 QRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMS 3821
Query: 2168 REHREA----SKVP----------LNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKG 2213
+E + A + P ++ +H + M Y + V F
Sbjct: 3822 QEEKAAYLSDPRAPPCEYKDWLTKMSGKHDVGAYMLM-YKGANRTETVTSFRKRESKVPA 3880
Query: 2214 QDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHI 2273
L + S S E++L R+ + S A++ + +ILG+GDRH +N M+ TG V+ I
Sbjct: 3881 DLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGI 3940
Query: 2274 DFGDCFEAAILREKYPEKVPFRLTRM---LTYAMEVSGIEGSFRITCENVMMVLRDNKES 2330
DFG F +A PE +PFRLTR L M+ +G+ S + + + R +
Sbjct: 3941 DFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMV---HALRAFRSDPGL 3997
Query: 2331 LMAILEAFAYDPLINW 2346
L ++ F +P +W
Sbjct: 3998 LTNTMDVFVKEPSFDW 4013
>CE22176 [TBLD] KOG0892 Protein kinase ATM/Tel1 involved in telomere length
regulation and DNA repair
Length = 759
Score = 108 bits (269), Expect = 1e-22
Identities = 80/301 (26%), Positives = 142/301 (46%), Gaps = 21/301 (6%)
Query: 2054 ELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDN 2113
++ PG Y +I ++ +FT+ P+ I+GSDGK Y+ + K +D+RQD
Sbjct: 297 KIGCPGDYST-TDLITWKRWKDVFTIADGISTPKIWEIEGSDGKWYKTVWK-KDDVRQDV 354
Query: 2114 LVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLL----GWVPNSDTFHVLIRE 2169
LV Q+F + N +L+ ++ Y +PL + G++ G V + + RE
Sbjct: 355 LVEQMFDVTNNMLEK--------AMLRTYNVVPLDTECGVIEFCGGTVSLKEVMCGVTRE 406
Query: 2170 ---HREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRS 2226
HRE + ++ + ++ ++V V + + +
Sbjct: 407 GGLHREFNSEEVSASKVSSMMRQVQTESTETRRQVFV---EICQQYSPVFRHFFYTNFST 463
Query: 2227 SESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILRE 2286
++ W ++ Y +SLA S+V YI+GLGDRH SN++ D+ VHID G E +
Sbjct: 464 AQIWRQKIINYRQSLATWSIVCYIVGLGDRHASNILFDQKLCTFVHIDLGMILEYSKRTL 523
Query: 2287 KYPEKVPFRLTRMLTYAMEVSGIE-GSFRITCENVMMVLRDNKESLMAILEAFAYDPLIN 2345
PE+VPFR+TR + + + GIE G C +M L++N + ++ + A + + N
Sbjct: 524 PVPEQVPFRITRDVLDPILIEGIENGQLAEECTQIMEKLKENGKVILGVASALLRETMTN 583
Query: 2346 W 2346
+
Sbjct: 584 F 584
>CE28250 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2514
Score = 99.4 bits (246), Expect = 7e-20
Identities = 94/381 (24%), Positives = 157/381 (40%), Gaps = 46/381 (12%)
Query: 2070 ITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNN 2129
I F V+ S +P + + G+ + I K +D+ +D ++ + N LL +
Sbjct: 2172 IHDFSDKVKVLHSNTKPVIIKLTTKTGRIVRLICKKDDDLSKDYHFTKMVEMCNDLLMKD 2231
Query: 2130 PESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMA 2189
++ + + Y IPL + G++ ++ +F+ E + + L+
Sbjct: 2232 EQTRIQKMTATTYSVIPLGKQGGIIEFMEGVTSFY-------ETLDKLMGMTSGEWLEKL 2284
Query: 2190 PDYD-NLTLLQKVEVFTYALDNT-KGQDLYKVLWLKSRSSES--WLERRTTYTRSLAVMS 2245
++ ++ + K E Y + K + W + + E+ W R + +S AVMS
Sbjct: 2285 KFWNTHMKPMGKEERTKYFREVACKNTPVVMGKWFRIQYPEAGQWFASRKLFAKSTAVMS 2344
Query: 2246 MVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAME 2305
++GYI GLGDRH NLM+ TGK +H+DF F PE VPFRLT+ + M
Sbjct: 2345 VIGYIFGLGDRHTKNLMV-HTTGKCIHVDFDMIFNKGETLGT-PELVPFRLTQNMINGMG 2402
Query: 2306 VSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPL 2365
++G FR CE + V R+N +E + D L N D P+ ++ D +
Sbjct: 2403 EVALDGEFRTVCEQALRVFRENSYE----IEKYIAD-LPNLVADFPSN---KRAPKDFDM 2454
Query: 2366 ANPSELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQ 2425
+ L+ +R T L R P + V
Sbjct: 2455 SEAKRLV-----------------SGRLRGQIMTAKLYR--------SNPISHPMQVSQL 2489
Query: 2426 VDKLIQQATSVENLCQHYIGW 2446
LI+ ATS E L + Y+GW
Sbjct: 2490 ASSLIELATSEEKLSEMYLGW 2510
>CE25103 [TBLD] KOG0890 Protein kinase of the PI-3 kinase family involved in
mitotic growth DNA repair and meiotic recombination
Length = 2531
Score = 99.4 bits (246), Expect = 7e-20
Identities = 94/381 (24%), Positives = 157/381 (40%), Gaps = 46/381 (12%)
Query: 2070 ITHFEPIFTVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNN 2129
I F V+ S +P + + G+ + I K +D+ +D ++ + N LL +
Sbjct: 2189 IHDFSDKVKVLHSNTKPVIIKLTTKTGRIVRLICKKDDDLSKDYHFTKMVEMCNDLLMKD 2248
Query: 2130 PESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMA 2189
++ + + Y IPL + G++ ++ +F+ E + + L+
Sbjct: 2249 EQTRIQKMTATTYSVIPLGKQGGIIEFMEGVTSFY-------ETLDKLMGMTSGEWLEKL 2301
Query: 2190 PDYD-NLTLLQKVEVFTYALDNT-KGQDLYKVLWLKSRSSES--WLERRTTYTRSLAVMS 2245
++ ++ + K E Y + K + W + + E+ W R + +S AVMS
Sbjct: 2302 KFWNTHMKPMGKEERTKYFREVACKNTPVVMGKWFRIQYPEAGQWFASRKLFAKSTAVMS 2361
Query: 2246 MVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAME 2305
++GYI GLGDRH NLM+ TGK +H+DF F PE VPFRLT+ + M
Sbjct: 2362 VIGYIFGLGDRHTKNLMV-HTTGKCIHVDFDMIFNKGETLGT-PELVPFRLTQNMINGMG 2419
Query: 2306 VSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPL 2365
++G FR CE + V R+N +E + D L N D P+ ++ D +
Sbjct: 2420 EVALDGEFRTVCEQALRVFRENSYE----IEKYIAD-LPNLVADFPSN---KRAPKDFDM 2471
Query: 2366 ANPSELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQ 2425
+ L+ +R T L R P + V
Sbjct: 2472 SEAKRLV-----------------SGRLRGQIMTAKLYR--------SNPISHPMQVSQL 2506
Query: 2426 VDKLIQQATSVENLCQHYIGW 2446
LI+ ATS E L + Y+GW
Sbjct: 2507 ASSLIELATSEEKLSEMYLGW 2527
>At2g17930 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3795
Score = 91.3 bits (225), Expect = 2e-17
Identities = 113/434 (26%), Positives = 183/434 (42%), Gaps = 49/434 (11%)
Query: 2038 LDLQHVSPKLAAAKDLELAVPGTYHAGKPVI--------RITHFEPIFTVISSKQRPRRL 2089
L L+ S L +++ +PG Y A + V R+ PI S R RL
Sbjct: 3382 LRLEDESRVLRDFNVVDVEIPGQYFADQEVAPDHTVKLDRVGADVPIVRRHGSSFR--RL 3439
Query: 2090 SIKGSDGKDYQYIVKGH--EDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPL 2147
++ GSDG +IV+ + R D ++QLF ++N + + ES +RH+ I IP+
Sbjct: 3440 TLIGSDGSQKHFIVQTSLTPNARSDERILQLFRVMNQMFDKHKESRRRHIGIHTPIIIPV 3499
Query: 2148 SPKSGLLGWVPNSDTFHVLIREH--REASKVPLNIEH-------RIMLQMAPD-YDNLTL 2197
+ ++ +TF + H R + L I H I Q++ + +L L
Sbjct: 3500 WSQVRMVEDDLMYNTFLEVYENHCARNDREADLPITHFKEQLNQAISGQISAEAIGDLRL 3559
Query: 2198 LQKVEVF-TYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDR 2256
+++ T D+ Q +YK L S W ++ + LAV S + ++L +G R
Sbjct: 3560 QAYIDITKTLVNDSIFSQYMYKTLM---SGSHMWAFKKQ-FAVQLAVSSFMSFMLQIGGR 3615
Query: 2257 HPSNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRIT 2316
P+ ++ + TGK+ DF ++A + E + E VPFRLTR + G+EG +
Sbjct: 3616 SPNKVLFAKNTGKMFQTDFHPAYDANGMIE-FNEPVPFRLTRNMQAFFSQFGVEGLLMSS 3674
Query: 2317 -CENVMMVLRDNK-ESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRK 2374
C V+ + E L L F D L++W P + G + NP+EL K
Sbjct: 3675 MCSAAQAVISSKQNEHLRYQLAMFFRDELLSWFGRRPLGVPIPPVG-GIATLNPAELKHK 3733
Query: 2375 GVITVEDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQE--LSVPDQVDKLIQQ 2432
VED K ++ IA + + E SV V++L++
Sbjct: 3734 VNANVEDVIKR----------------IRGIAPQYFSEEDENTVEPPQSVQRGVNELVEA 3777
Query: 2433 ATSVENLCQHYIGW 2446
A S NLC W
Sbjct: 3778 ALSPRNLCMMDPTW 3791
>Hs4507691 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3830
Score = 88.2 bits (217), Expect = 2e-16
Identities = 139/667 (20%), Positives = 256/667 (37%), Gaps = 114/667 (17%)
Query: 1852 WLEVIPQLISRIHQPNQTVSRSLLSLLADLGKAHPQALVYP---LTVAIKSDSVSRQRA- 1907
WL IPQL++ + + LL+L++ +G+ +PQA+ +P L + +K + R ++
Sbjct: 3202 WLAWIPQLLTCLVGSE---GKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSD 3258
Query: 1908 ------------ALSIIDKMRMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQF 1955
I+ R P L+ E + D+++ WHE L+ +
Sbjct: 3259 PGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKC 3318
Query: 1956 FGE-----------------------------------HNTEKMFATLEPLHEMLKRGPE 1980
+ N MF++ + +R
Sbjct: 3319 YSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAAS-ESLARRAQA 3377
Query: 1981 TLREISFQNSFGRDLNDAHEWVMNYKRTKDINNLNQAWDIYYNVFRRISRKLPQLQTLDL 2040
T ++ FQ G+ D + + + ++NL + + +++LP+ ++
Sbjct: 3378 TAQDPVFQKLKGQFTTD---FDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEE 3434
Query: 2041 QHVSPKLAAAKDLELAVPGTYHAGKPV---IRITHFEPIFTVISSKQRP-RRLSIKGSDG 2096
+ +A+ E+ +PG + KP I+I F P ++ RRL I+G +G
Sbjct: 3435 KCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNG 3494
Query: 2097 KDYQYIVKGHE---DIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGL 2153
K Y Y+V + R++ V+QL L+N L+ E+ +RHL + +SP+ L
Sbjct: 3495 KIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRL 3554
Query: 2154 LGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQK----------VEV 2203
+ P+S + V I + R A K IEH + YD L +Q ++
Sbjct: 3555 VEDNPSSLSL-VEIYKQRCAKK---GIEHDNPISRY--YDRLATVQARGTQASHQVLRDI 3608
Query: 2204 FTYALDNTKGQDLYK--VLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNL 2261
N + + K L +++ W R+ +T LA++ ++L L +P L
Sbjct: 3609 LKEVQSNMVPRSMLKEWALHTFPNATDYWTFRK-MFTIQLALIGFAEFVLHLNRLNPEML 3667
Query: 2262 MLDRVTGK--VVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCEN 2319
+ + TGK V + F L P VPFRLT ++ + G+ G +
Sbjct: 3668 QIAQDTGKLNVAYFRFDINDATGDLDANRP--VPFRLTPNISEFLTTIGVSGPLTASMIA 3725
Query: 2320 VMMVLRDNKESLMAILEAFAYDPLINWGFDLPTQAVMEQTGIDLPLANPSELLRKGVITV 2379
V + IL+ D +I W + E T L A E
Sbjct: 3726 VARCFAQPNFKVDGILKTVLRDEIIAW-----HKKTQEDTSSPLSAAGQPE--------- 3771
Query: 2380 EDAAKMELQQKAEVRNARATLVLKRIADKLTGNDFPRYQELSVPDQVDKLIQQATSVENL 2439
M+ QQ + T ++ R+ ++ +++ +V+ L+ A S++NL
Sbjct: 3772 ----NMDSQQLVSLVQKAVTAIMTRL------HNLAQFE--GGESKVNTLVAAANSLDNL 3819
Query: 2440 CQHYIGW 2446
C+ W
Sbjct: 3820 CRMDPAW 3826
>YHR099w [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3744
Score = 82.0 bits (201), Expect = 1e-14
Identities = 148/655 (22%), Positives = 256/655 (38%), Gaps = 113/655 (17%)
Query: 1801 AIKGFFRSIALSQSSSLQDTLRLLTLWFKFGGIPEAAQAMHEGF----GLIKIDNWLEVI 1856
AI + ++ L ++S +++ L + LW I +A+ + F G I + W+ I
Sbjct: 3081 AISCYLQAAGLYKNSKIRELLCRI-LWLI--SIDDASGMLTNAFDSFRGEIPVWYWITFI 3137
Query: 1857 PQLISRIHQPNQTVSRSLLSLLADLGKAHPQALVYPLTVAIKSDSVSRQRAALSII-DKM 1915
PQL++ + + R +L +A K++PQAL + L K D QR ++++ DK
Sbjct: 3138 PQLLTSLSHKEANMVRHILIRIA---KSYPQALHFQLRTT-KEDFAVIQRQTMAVMGDKP 3193
Query: 1916 RMHSPKLVDQAELVSDELIRVAVLWHELWYEGLEDASRQF---FGEHNTEKMFATLEPLH 1972
+ Q EL + + L LE Q F E +F + L
Sbjct: 3194 DTNDRNGRRQPWEYLQELNNILKTAYPLLALSLESLVAQINDRFKSTTDEDLFRLINVL- 3252
Query: 1973 EMLKRGPETLREISFQNSFGRDLNDAHEWVMNYKRT-----------KDINNLNQAWDIY 2021
L G + F + + + ++ + T D + ++ Y
Sbjct: 3253 --LIDGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYIRPKFNADFIDNKPDYETY 3310
Query: 2022 YNVFR----RISRKLPQLQTLD-LQHVSPKLAA---AKDLELAVPGTYHAGKP----VIR 2069
R R+ KL + + L+ + P L+ K ++ +PG Y K I+
Sbjct: 3311 IKRLRYWRRRLENKLDRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYLLNKDNNVHFIK 3370
Query: 2070 ITHFEPIFTVISSKQRP-RRLSIKGSDGKDYQYIVK--GHEDIRQDNLVMQLFGLVNTLL 2126
I F P + RRL I+G DG + + V+ R++ + QL+ L N L
Sbjct: 3371 IARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERMFQLYRLFNKSL 3430
Query: 2127 QNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVP--------- 2177
N E+ +R + AIPLSP+ ++ +S +F L H E K
Sbjct: 3431 SKNVETRRRSIQFNLPIAIPLSPQVRIMN---DSVSFTTLHEIHNEFCKKKGFDPDDIQD 3487
Query: 2178 -----LNIEHRIMLQMAPDYDNLTLLQKVEVF----TYALDNTKGQDLYKVLWLKSRSSE 2228
LN H L APD +T+L KVE+F T + + +D + L+ ++ +
Sbjct: 3488 FMADKLNAAHDDALP-APD---MTIL-KVEIFNSIQTMFVPSNVLKDHFTSLF--TQFED 3540
Query: 2229 SWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKY 2288
WL R+ + + + Y++ + +R P + +D+ +G V F +L ++
Sbjct: 3541 FWLFRKQ-FASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNV--------FTLEMLPSRF 3591
Query: 2289 P-------------------------EKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMV 2323
P E VPFRLT + + S +EG F + +
Sbjct: 3592 PYERVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRA 3651
Query: 2324 LRDNKESLMAILEAFAYDPLINWGFDL-------PTQAVMEQTGIDLPLANPSEL 2371
L + L L F D +I+W +L P M QT +DL + ++L
Sbjct: 3652 LIEPDNELNTYLALFIRDEIISWFSNLHRPIIENPQLREMVQTNVDLIIRKVAQL 3706
>SPAC1F5.11c [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3655
Score = 74.3 bits (181), Expect = 2e-12
Identities = 78/328 (23%), Positives = 137/328 (40%), Gaps = 38/328 (11%)
Query: 2054 ELAVPGTYHAGK----PVIRITHFEPIFTVISSKQRP-RRLSIKGSDGKDY----QYIVK 2104
E+ +PG Y K +R+ F P ++ +RL+++G DGK Y QY
Sbjct: 3261 EVEIPGQYLLDKNNNNDFVRLERFVPNVDLVRGHTMCYKRLTLRGYDGKLYPFALQYPAT 3320
Query: 2105 GHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFH 2164
H R++ ++QL G NT+L++ E R+ + Q +IPLS ++ P+ T
Sbjct: 3321 RHS--RREERMLQLLGTFNTVLRSKIEIQNRNFSFQIPSSIPLSSHMRIIADKPSYVTMQ 3378
Query: 2165 VLIREHREASKVPLNIEHRI--------MLQM----APDYDNLTLLQKVEVFTYALDNTK 2212
+ E+ + +PL+ R ++Q+ A N T+ +K ++F +
Sbjct: 3379 TISDEYCKNRGMPLDYGIRFYFDRLQTGLIQLKRASASMLSNSTVEEKKQIFRQRALQLR 3438
Query: 2213 GQ------------DLYKVLWLKS--RSSESWLERRTTYTRSLAVMSMVGYILGLGDRHP 2258
Q +Y + K+ R + W RR T+T A M ++ Y+ +G R P
Sbjct: 3439 MQLLETLNSSVFPESIYYDYFYKTFERYCDFWFFRR-TFTTQYAYMIIMTYVFNIGGRSP 3497
Query: 2259 SNLMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCE 2318
L + + +G+V+ D + E VPFRLT + Y + G+EG
Sbjct: 3498 QKLFIVKDSGQVMSQDLLPSMTSNQPVFHNTEAVPFRLTPPIQYLISDLGVEGLLSGLVM 3557
Query: 2319 NVMMVLRDNKESLMAILEAFAYDPLINW 2346
++ L + L + D + W
Sbjct: 3558 SIAQSLSSPTTDIKQYLSLYVRDEVFWW 3585
>Hs19923289 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic subunit (p110)
Length = 1044
Score = 68.6 bits (166), Expect = 1e-10
Identities = 79/314 (25%), Positives = 128/314 (40%), Gaps = 65/314 (20%)
Query: 2029 SRKLPQLQTLDLQHVSPKLAAAKDLELAVPGTYHAGKPVIRITHFEPIF----TVISSKQ 2084
S+K P+ QT +L H+ + E + H P+ T + T + SK
Sbjct: 703 SQKTPKPQTKELMHLCMRQ------EAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM 756
Query: 2085 RPRRLSIKGSD---GKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQ 2141
+P + + G I K +D+RQD L +Q+ L++ L + L +
Sbjct: 757 KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLD----LRMTP 812
Query: 2142 YPAIPLSPKSGLLGWVPNSDTF-HVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQK 2200
Y +P ++GL+ V SDT ++ + + A+ N +
Sbjct: 813 YGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKD------------------- 853
Query: 2201 VEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTT-YTRSLAVMSMVGYILGLGDRHPS 2259
AL N WLKS++ L+R +T S A + Y+LG+GDRH
Sbjct: 854 ------ALLN----------WLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSD 897
Query: 2260 NLMLDRVTGKVVHIDFGDCFEAAILREKY---PEKVPFRLTRMLTYAMEVSGIEGS---- 2312
N+M+ R +G++ HIDFG + K+ E+VPF LT + ++ S
Sbjct: 898 NIMI-RESGQLFHIDFGHFL--GNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFE 954
Query: 2313 -FRITCENVMMVLR 2325
FR CE +LR
Sbjct: 955 RFRGYCERAYTILR 968
>SPAC458.05 [TU] KOG0906 Phosphatidylinositol 3-kinase VPS34 involved in signal
transduction
Length = 801
Score = 65.5 bits (158), Expect = 1e-09
Identities = 55/199 (27%), Positives = 83/199 (41%), Gaps = 41/199 (20%)
Query: 2078 TVISSKQRPRRLSIKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHL 2137
TV S +P RL K DG Y I K +D+RQD LV+Q+ L++ LL+ + L
Sbjct: 520 TVFKSTMQPLRLLFKCQDGSKYPIIFKNGDDLRQDQLVIQILTLMDKLLKKE----KLDL 575
Query: 2138 NIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTL 2197
+++ Y + P G + +VP+ +L H + + PD D L
Sbjct: 576 HLKPYRILATGPTHGAVQFVPSKTLATILAEYHGSVL--------AYLRENNPD-DGLN- 625
Query: 2198 LQKVEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRH 2257
+ A+DN Y RS A ++ Y+LG+GDRH
Sbjct: 626 SANYGIDPVAMDN--------------------------YVRSCAGYCVITYLLGVGDRH 659
Query: 2258 PSNLMLDRVTGKVVHIDFG 2276
NL++ + G H DFG
Sbjct: 660 LDNLLITK-DGHFFHADFG 677
>7302249 [TBLD] KOG0889 Histone acetyltransferase SAGA TRRAP/TRA1 component
PI-3 kinase superfamily
Length = 3435
Score = 65.5 bits (158), Expect = 1e-09
Identities = 104/460 (22%), Positives = 188/460 (40%), Gaps = 60/460 (13%)
Query: 2011 INNLNQAWDIYYNVFRRISRKLPQLQTLD-----LQHVSPKLAAAK-DLELAVPGTYHAG 2064
++NL + V +KLP ++ L + S K A + EL +P + H
Sbjct: 3008 LHNLISKLKTWIKVLETKVKKLPTSFLIEDKCRFLSNFSQKTAEVELPGELLIPLSSHY- 3066
Query: 2065 KPVIRITHFEPIFTVISSKQRP-RRLSIKGSDGKDYQYIV---KGHEDIRQDNLVMQLFG 2120
+RI F P ++ RRL I+G++GK Y Y+V G D R++ V+QL
Sbjct: 3067 --YVRIARFMPRVEIVQKNNTAARRLYIRGTNGKIYPYLVVLDSGLGDARREERVLQLKR 3124
Query: 2121 LVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNI 2180
++N L+ E+ +R LNI +P+SP+ L PNS + + ++ ++ +V +
Sbjct: 3125 MLNYYLEKQKETSRRFLNITVPRVVPISPQMRLAEDNPNSISLLKIFKKCCQSMQVDYD- 3183
Query: 2181 EHRIMLQMAPDYDNLTLLQK----------VEVFTYALDNTKGQDLYKVLWLKS--RSSE 2228
+ + YD L+ +Q E+F+ + L K LK+ +++
Sbjct: 3184 -----MPIVKYYDRLSEVQARGTPTTHTLLREIFSEIQWTMVPKTLLKHWALKTFLAATD 3238
Query: 2229 SWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTG--KVVHIDFGDCFEAAILRE 2286
W R T LA+ + + L L + + L + +G + + F + L +
Sbjct: 3239 FW-HFRKMLTLQLALAFLCEHALNLTRLNADMMYLHQDSGLMNISYFKFDVNDDKCQLNQ 3297
Query: 2287 KYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMMVLRDNKESLMAILEAFAYDPLINW 2346
P VPFRLT + + GI G L +IL+ D +I
Sbjct: 3298 HRP--VPFRLTPNVGEFITHFGITGPLSAAIVATARCFIQPNYKLSSILQTILRDEII-- 3353
Query: 2347 GFDLPTQAVMEQTGIDLPLANPSELLRKGVITVEDAAKMELQQKAEVRNARATLVLKRIA 2406
+++ G +L+ D ME + N+ +++ R
Sbjct: 3354 --------ALQKKGF-----RECKLIEGSEDRYSDGNCME--HSVNIVNSAVDIIMTRF- 3397
Query: 2407 DKLTGNDFPRYQELSVPDQVDKLIQQATSVENLCQHYIGW 2446
+K++ D +++SV L+Q AT+++NLC+ W
Sbjct: 3398 NKISYFDSIENKKISV------LVQSATNIDNLCRMDPAW 3431
>Hs5453894 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic subunit (p110)
Length = 1070
Score = 61.2 bits (147), Expect = 2e-08
Identities = 62/233 (26%), Positives = 100/233 (42%), Gaps = 50/233 (21%)
Query: 2102 IVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSD 2161
I K +D+RQD L +Q+ L++ L + L + Y + +SGL+ V S+
Sbjct: 803 IFKNGDDLRQDMLTLQMLRLMDLLWKEAGLD----LRMLPYGCLATGDRSGLIEVVSTSE 858
Query: 2162 TFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLW 2221
T + + LN + + A ++ LL W
Sbjct: 859 TI----------ADIQLNSSN---VAAAAAFNKDALLN---------------------W 884
Query: 2222 LKSRSSESWLERRTT-YTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFE 2280
LK +S L+R +T S A + Y+LG+GDRH N+M+ + TG++ HIDFG
Sbjct: 885 LKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKK-TGQLFHIDFGHIL- 942
Query: 2281 AAILREKY---PEKVPFRLTRMLTYAMEVSGIE-----GSFRITCENVMMVLR 2325
+ K+ E+VPF LT + ++ G FR CE+ ++LR
Sbjct: 943 -GNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILR 994
>Hs5453892 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic subunit (p110)
Length = 1068
Score = 60.1 bits (144), Expect = 4e-08
Identities = 61/228 (26%), Positives = 103/228 (44%), Gaps = 48/228 (21%)
Query: 2079 VISSKQRPRRLSIKGSD------GKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPES 2132
++SS +RP L+ + D ++ + I K +D+RQD L +Q+ ++ + QN
Sbjct: 771 IMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQ--- 827
Query: 2133 FQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDY 2192
L + Y + + GL+ V NS T + I+ + L+ A +
Sbjct: 828 -GLDLRMLPYGCLSIGDCVGLIEVVRNSHTI--------------MQIQCKGGLKGALQF 872
Query: 2193 DNLTLLQKVEVFTYALDNTKGQDLYKVLWLKSRS-SESWLERRTTYTRSLAVMSMVGYIL 2251
++ TL Q WLK ++ E + +TRS A + +IL
Sbjct: 873 NSHTLHQ---------------------WLKDKNKGEIYDAAIDLFTRSCAGYCVATFIL 911
Query: 2252 GLGDRHPSNLMLDRVTGKVVHIDFGDCFEAAILREKYP-EKVPFRLTR 2298
G+GDRH SN+M+ + G++ HIDFG + + Y E+VPF LT+
Sbjct: 912 GIGDRHNSNIMV-KDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQ 958
>At5g64070 [TU] KOG0903 Phosphatidylinositol 4-kinase involved in intracellular
trafficking and secretion
Length = 1121
Score = 59.7 bits (143), Expect = 6e-08
Identities = 66/262 (25%), Positives = 111/262 (42%), Gaps = 53/262 (20%)
Query: 2083 KQRPRRLSIKGS-DGKDYQ-YIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQ 2140
+ R R+ SI G G D + IVK +D RQ++L +QL + Q L ++
Sbjct: 841 RDRIRKASIYGKLPGWDLRSIIVKSGDDCRQEHLAVQLISHFYDIFQEAGLP----LWLR 896
Query: 2141 QYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQK 2200
Y + S + L+ +P++ + H +I+ R Y N+T L+
Sbjct: 897 PYEVLVTSSYTALIETIPDTASIH--------------SIKSR--------YPNITSLRD 934
Query: 2201 VEVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSN 2260
V Y +S S+ + + S+A S+V Y+L + DRH N
Sbjct: 935 FFVAKY-----------------KENSPSFKLAQRNFVESMAGYSLVCYLLQVKDRHNGN 977
Query: 2261 LMLDRVTGKVVHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAM--EVSGIEGS----FR 2314
L+LD G ++HIDFG + + E PF+LTR L M + G+ F+
Sbjct: 978 LLLDE-EGHIIHIDFGFMLSNSPGGVNF-ESAPFKLTRELLEVMDSDADGVPSEFFDYFK 1035
Query: 2315 ITCENVMMVLRDNKESLMAILE 2336
+ C + R + E ++ ++E
Sbjct: 1036 VLCIQGFLTCRKHAERIILLVE 1057
>7290340 [T] KOG0902 Phosphatidylinositol 4-kinase
Length = 2113
Score = 59.3 bits (142), Expect = 7e-08
Identities = 59/252 (23%), Positives = 98/252 (38%), Gaps = 51/252 (20%)
Query: 2033 PQLQTLDLQHVS--PKLAAAKDLELAVPGTYHAGKPVIRITHFEPIFTVISSKQRPRRLS 2090
P+ LD+ + S P +AAK LA Y G + E S + L
Sbjct: 1792 PEAMVLDIDYSSGTPMQSAAKAPYLARFRVYRCGITELETRAMEVSNNPNSQEDAKMTLG 1851
Query: 2091 IKGSDGKDYQYIVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPK 2150
++ I K +D+RQD L +Q+ T+ +N + L + Y + +P
Sbjct: 1852 VESWQAA----IFKVGDDVRQDMLALQVI----TIFKNIFQQVGLDLFLFPYRVVATAPG 1903
Query: 2151 SGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDN 2210
G++ VPN+ + L R+
Sbjct: 1904 CGVIECVPNAKSRDQLGRQ----------------------------------------T 1923
Query: 2211 TKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKV 2270
G Y SS+ + R + +S+A S++GY+L + DRH N+M+D+ G +
Sbjct: 1924 DSGLSEYFQHQYGDESSKEFQAARANFVKSMAAYSLIGYLLQIKDRHNGNIMIDK-DGHI 1982
Query: 2271 VHIDFGDCFEAA 2282
+HIDFG FE++
Sbjct: 1983 IHIDFGFMFESS 1994
>CE23035 [T] KOG0902 Phosphatidylinositol 4-kinase
Length = 2121
Score = 57.0 bits (136), Expect = 4e-07
Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 45/181 (24%)
Query: 2102 IVKGHEDIRQDNLVMQLFGLVNTLLQNNPESFQRHLNIQQYPAIPLSPKSGLLGWVPNSD 2161
I K +D+RQD L +QL L++N + + Y + SP G++ VPNS
Sbjct: 1867 IFKVGDDVRQDMLALQLM----QLMKNVWAGLGLPVRVFPYRVVATSPGCGVIECVPNSK 1922
Query: 2162 TFHVLIREHREASKVPLNIEHRIMLQMAPDYDNLTLLQKVEVFTYALDNTKGQDLYKVLW 2221
+ L R+ + Y T+ D
Sbjct: 1923 SRDQLGRQ-------------------------------TDFGLYEYFKTQYGD------ 1945
Query: 2222 LKSRSSESWLERRTTYTRSLAVMSMVGYILGLGDRHPSNLMLDRVTGKVVHIDFGDCFEA 2281
SSE++ E R + RS+A S+ ++L + DRH N+M+D + G ++HIDFG FE+
Sbjct: 1946 ---ESSETFQEARRNFVRSMAAYSVFSFLLQIKDRHNGNIMID-LDGHIIHIDFGFMFES 2001
Query: 2282 A 2282
+
Sbjct: 2002 S 2002
>CE23506 [T] KOG0904 Phosphatidylinositol 3-kinase catalytic subunit (p110)
Length = 1146
Score = 54.3 bits (129), Expect = 2e-06
Identities = 63/278 (22%), Positives = 117/278 (41%), Gaps = 41/278 (14%)
Query: 2079 VISSKQRPRRLSIKGSDGKDYQY------IVKGHEDIRQDNLVMQLFGLVNTLLQNNPES 2132
V+ S +RP L K + K + I K +D+RQD LV+Q+ +++ + + +
Sbjct: 823 VLGSAKRPLMLHWKNKNPKSDLHLPFCAMIFKNGDDLRQDMLVLQVLEVMDNIWK----A 878
Query: 2133 FQRHLNIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREASKVPLNIEHRIMLQMAPDY 2192
+ Y +P+ G++ VPN T + +V + + + P +
Sbjct: 879 ANIDCCLNPYAVLPMGEMIGIIEVVPNCKTIFEI--------QVGTGFMNTAVRSIDPSF 930
Query: 2193 DNLTLLQKV----EVFTYALDNTKGQDLYKVLWLKSRSSESWLERRTTYTRSLAVMSMVG 2248
N + ++ E D+TK K+ +++ + + E + S S+
Sbjct: 931 MNKWIRKQCGIEDEKKKSKKDSTKNPIEKKID--NTQAMKKYFESVDRFLYSCVGYSVAT 988
Query: 2249 YILGLGDRHPSNLMLDRVTGKVVHIDFGDCF-----EAAILREKYPEKVPFRLT-RMLTY 2302
YI+G+ DRH NLML GK HIDFG + I R++ PF LT +T
Sbjct: 989 YIMGIKDRHSDNLMLTE-DGKYFHIDFGHILGHGKTKLGIQRDRQ----PFILTEHFMTV 1043
Query: 2303 AMEVSGIEGS------FRITCENVMMVLRDNKESLMAI 2334
++G+ F+ C V+ +N++ +++
Sbjct: 1044 IRSGKSVDGNSHELQKFKTLCVEAYEVMWNNRDLFVSL 1081
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.135 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 139,482,434
Number of Sequences: 60738
Number of extensions: 5900997
Number of successful extensions: 16871
Number of sequences better than 1.0e-05: 43
Number of HSP's better than 0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 16455
Number of HSP's gapped (non-prelim): 189
length of query: 2450
length of database: 30,389,216
effective HSP length: 123
effective length of query: 2327
effective length of database: 22,918,442
effective search space: 53331214534
effective search space used: 53331214534
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)