ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactII3594 good YUJ KOG2021 Intracellular trafficking, secretion, and vesicular transport Nuclear mRNA export factor receptor LOS1/Exportin-t (importin beta superfamily)
r_klactII3594 good YUJ KOG2021 Nuclear structure Nuclear mRNA export factor receptor LOS1/Exportin-t (importin beta superfamily)
r_klactII3594 good YUJ KOG2021 Translation, ribosomal structure and biogenesis Nuclear mRNA export factor receptor LOS1/Exportin-t (importin beta superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactII3594 1237212 1234024 -1063
(1063 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL205w [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1/E... 808 0.0
SPBP8B7.09c [YUJ] KOG2021 Nuclear mRNA export factor receptor LO... 319 2e-86
Hs8051636 [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1... 235 3e-61
At1g72560 [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1... 170 1e-41
CE27871 [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1/E... 103 1e-21
>YKL205w [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1/Exportin-t
(importin beta superfamily)
Length = 1100
Score = 808 bits (2087), Expect = 0.0
Identities = 467/1133 (41%), Positives = 671/1133 (59%), Gaps = 106/1133 (9%)
Query: 1 MSHIQQAVDIANSSTAGNDLKKQALDFLQQLKSSEDAVQVFSQYLQDPVASDVGRFFALQ 60
+ IQQ V+ N + K+QA++ L +KSSE+A+++F + + ++D+ +F+ L
Sbjct: 2 LERIQQLVNAVNDPRSDVATKRQAIELLNGIKSSENALEIFISLVINENSNDLLKFYGLS 61
Query: 61 VLSEQALE-LPANHEKLYALQQSALQFLRTQLENSSSDGARXXXXXXXXXXXXXTPPEFV 119
L E E + AN L ++ ++L+ Q+ + P+F+
Sbjct: 62 TLIELMTEGVNANPNGLNLVKFEITKWLKFQVLGNKQTKL----------------PDFL 105
Query: 120 RNKVAELFAHLFYNMYGEVNNNMWSSFFVDLIQLVGIASLRDSKSTGVEFNAI-GLDLFF 178
NK++E+ LF MY + N N W+SFF DL+ L + S + S + N + GL+ F
Sbjct: 106 MNKISEVLTTLFMLMYSDCNGNQWNSFFDDLMSLFQVDSAISNTSPSTDGNILLGLEFFN 165
Query: 179 RICASINTEIGDQAFVRSKEVQLKNNELKDYMRVQDVELLSNIWFSALLNCQQL----PV 234
++C IN+EI DQ+F+RSKE QLKNN +KD+MR D+ LSN+WF L +Q+ P
Sbjct: 166 KLCLMINSEIADQSFIRSKESQLKNNNIKDWMRDNDIMKLSNVWFQCLKLDEQIVSQCPG 225
Query: 235 LASLVLQCVGSYISWIDINLIVQQS--YIGTIYEYLKFPQTKLACGQCLCEIISKKMKPA 292
L + L C+GS+ISWIDINLI+ + Y+ IY++L +TK++C C+ IISKKMKP
Sbjct: 226 LINSTLDCIGSFISWIDINLIIDANNYYLQLIYKFLNLKETKISCYNCILAIISKKMKPM 285
Query: 293 DKLQLLSMLNLTDRVVATGSA----------EDLDVLEQMAKLTNGVALELSMVMDQCND 342
DKL L+M+NLT+ + A ++L+V E + KL +E +++++Q ND
Sbjct: 286 DKLAFLNMINLTNELTYYHQAISMNPQIITFDNLEVWESLTKLITSFGIEFTIIIEQVND 345
Query: 343 SQEL-----QSVSSAADEQIINVVSPLVLKFMAHEYDSVTQQCFSFVTNYLAVMKKLFAL 397
Q+L QSV S D ++ + P++L+FM +E+DS+T + F F +NYLA +KK A
Sbjct: 346 DQKLDTLYKQSVISNVDSILLEKIIPILLEFMNNEFDSITAKTFPFWSNYLAFLKKYKA- 404
Query: 398 GGKPGSAVAVNSKRIPIDPAHLNFLKSLGTVCVLKMKIDDSCDSIDDNEEIDEFVENIRS 457
P P H +FL + +C +MK D + DD EE F E +R
Sbjct: 405 -SSPNFV-----------PLHKDFLDNFQQICFKRMKFSDDEVTQDDFEE---FNETVRF 449
Query: 458 KLKTFQDSIAVINPELYFDIISDNIEQSIT--EQQDWRVLELAIYQLHNFAESIRNNLFG 515
KLK FQ+ I VI+P L+ + IS I ++ + + W++ EL IYQ+ N +E +NN FG
Sbjct: 450 KLKNFQEIIVVIDPSLFLNNISQEISANLMNCKNESWQIFELTIYQIFNLSECTKNNYFG 509
Query: 516 VNKTEISTSKPAQLMEKYMTTLLNHPT-LFQMNNPLVQISFFELVVRHNNFI-------- 566
+NK EI TS+P+ + +++ LL L ++N +QI F EL+V++ NFI
Sbjct: 510 LNKNEIMTSQPSLTLVRFLNELLMMKDFLLAIDNEQIQILFMELIVKNYNFIFSTSANTA 569
Query: 567 ---QVENKDLTLLNIFCTPFSMFSGNERVRLRTWYLFTRLIKTSKPKLS----------T 613
+ K L +LNIF + F+MF+ E VRLR+WYLFTR +K ++ L
Sbjct: 570 NATDDDEKYLLILNIFMSSFAMFNKRENVRLRSWYLFTRFLKLTRINLKKILFANKNLVN 629
Query: 614 DFXXXXXXXXXXXXXXXXXPLAQELDTIFDSQLYLFEGTGVLIG------------ANVN 661
+ + DTIFD+QLY+FEG G +I AN
Sbjct: 630 EITNKISPLLHIKVTSINAQGTDDNDTIFDNQLYIFEGIGFIITLNNSSQELTAATANTP 689
Query: 662 NEYEILDGVLTPLFADLEQCISAQVKNPQVVLQTHHILMAIGTVARGVHSGLVPDNQVNN 721
+Y+ILD +LTPLF LE CI+ Q +P V+L+ HHILMAIGT+ARG+H GLVP+NQVNN
Sbjct: 690 IDYDILDQILTPLFTQLEGCIT-QGASPVVILECHHILMAIGTLARGLHIGLVPENQVNN 748
Query: 722 AKVSERVICKSLIEKFSNIAEVILVTFSYFNKFETIRDAARFSFSRLIPILNNQIIPFAS 781
V++++I SLI KFSNIAEVILVTFS+FNKFE IRDA+RF+F+RLIPIL+N+I+PF +
Sbjct: 749 MVVNKKLINDSLIHKFSNIAEVILVTFSFFNKFENIRDASRFTFARLIPILSNKILPFIN 808
Query: 782 RLISIFLNS-DLKPLEMGDFIGFLGQMIHMFKDDDNCYQLFNNLFTPVVEKVFXXXX--- 837
+LI + L+S DLK EM DF+GFL Q+IHMF D +CYQLFN L TP++ KV
Sbjct: 809 KLIELILSSTDLKSWEMIDFLGFLSQLIHMFHTDTDCYQLFNQLLTPLINKVHSIIEEID 868
Query: 838 ------XXXXXXXXXXXXXXXNGKNVIVTDSFREKINLKKSYYGLLATFVSNNCTSLLLT 891
KN++VTDS+R+KI LKK+Y L +F +N+ TS+LL+
Sbjct: 869 EQHDQQSSSNKPIDTAVTATSVNKNIVVTDSYRDKILLKKAYCTFLQSFTNNSVTSILLS 928
Query: 892 ESNKNILPRVLTDLLSYTAEEIHETSTMKLSINVLVNFINFFGTGICTDPKDRNAINVNK 951
+ N+ ILP +L DL++YT +EI ETS MK+S+NVL NFI FG G C D D N K
Sbjct: 929 DINRAILPVILNDLVTYTPQEIQETSMMKVSLNVLCNFIKCFGNGTCLDNDDINKDPNLK 988
Query: 952 LDGLNEFFITTSIPLLFEIPFKPEYEFNIQDGGCRVIACDLSRLLKALYXXXXXXXXXXX 1011
+DGLNE+FI +P++FEIPF P Y+FNI++G + +A DL+RLL+ L+
Sbjct: 989 IDGLNEYFIMKCVPIIFEIPFNPIYKFNIKEGNFKTMAYDLARLLRELF---IVSSNPTT 1045
Query: 1012 XXXACVKYLTEIYFPQIQFPQSLVVEFINALGTLDAKQFEKYFV-QFITNMKQ 1063
CVKYLT+IY PQIQ PQ L ++ +N L T+ KQFEK+FV FI+ +KQ
Sbjct: 1046 NENECVKYLTQIYLPQIQLPQELTIQLVNMLTTMGQKQFEKWFVDNFISVLKQ 1098
>SPBP8B7.09c [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1/Exportin-t
(importin beta superfamily)
Length = 978
Score = 319 bits (817), Expect = 2e-86
Identities = 284/1095 (25%), Positives = 500/1095 (44%), Gaps = 162/1095 (14%)
Query: 4 IQQAVDIANSSTAGNDLKKQALDFLQQLKSSEDAVQVFSQYLQDPVASDVG-RFFALQVL 62
++ AV+ A + G +K+QA DF+ L+SS ++ + + R LQ L
Sbjct: 6 VENAVEAALDPSVGPIIKQQATDFIGSLRSSSTGWKICHEIFSEKTKYKPSTRLICLQTL 65
Query: 63 SEQALEL--PANHEKLYALQQSALQFLRTQLENSSSDGARXXXXXXXXXXXXXTPPEFVR 120
SE+ E +N +L ++ S +++ E S D P ++
Sbjct: 66 SEKVREWNNESNLLELQMIRDSVWSYIK---ELSFLD-----------------EPAYIS 105
Query: 121 NKVAELFAHLFYNMYGEVNNNMWSSFFVDLIQLVGIASLRDSKSTGVEFNAIGLDLFFRI 180
N V L LF +Y + W+ FF L ++ +S EF+ + + ++
Sbjct: 106 NAVQHLLTLLFLQLYP----SNWNDFFASLQGVIAASSQS-------EFS----NFYLKV 150
Query: 181 CASINTEIGDQAFVRSKEVQLKNNELKDYMRVQDVELLSNIWFSALL---NCQQLPVLAS 237
SI EI D +++ K+N +KD +R D+ + + + +L N + +
Sbjct: 151 LLSIGDEIADSLVLKTDVQIQKDNLVKDAIRANDMSDIVSFVYEMMLAYSNAKNYGTVG- 209
Query: 238 LVLQCVGSYISWIDINLIVQQSYIGTIYEYLKFPQTKLACGQCLCEIISKKMKPADKLQL 297
L LQ ++SWI+INLIV + + +Y +L+ + + A + + EI++KKMKP +KL L
Sbjct: 210 LCLQVYAQWVSWININLIVNEPCMNLLYSFLQIEELRCAACETMTEIVNKKMKPLEKLNL 269
Query: 298 LSMLNLTDRVVATGSAE---DLDVLEQMAKLTNGVALELSMVMDQCNDSQELQ-SVSSAA 353
L++LNL + + S E D + E +AKL N +EL + +D EL +
Sbjct: 270 LNILNL--NLFFSKSQEQSTDPNFDEHVAKLINAQGVELVAIK---SDPSELSPELKENC 324
Query: 354 DEQIINVVSPLVLKFMAHEYDSVTQQCFSFVTNYLAVMKKLFALGGKPGSAVAVNSKRIP 413
Q+ N+ P ++++++ +YD + F F+++ L ++K S
Sbjct: 325 SFQLYNLF-PYLIRYLSDDYDETSTAVFPFLSDLLVSLRK--------------ESSSKE 369
Query: 414 IDPAHLNFLKSLGTVCVLKMKIDDS--CDSIDDNEEIDEFVENIRSKLKTFQDSIAVINP 471
+ + FLKSL + KMK D+S D D+EE EF E +R KLK FQD+I I+
Sbjct: 370 LSASLKEFLKSLLEAIIKKMKYDESQEWDDDPDSEEEAEFQE-MRKKLKIFQDTINSIDS 428
Query: 472 ELYFDIISDNIEQS------ITEQQDWRVLELAIYQLHNFAESIRNNLFGVNKTEISTSK 525
L+ + I S ++ + W+++E A+Y+ + F E +R N+ + S +
Sbjct: 429 SLFSSYMYSAITSSLSTAATLSPENSWQLIEFALYETYIFGEGLRGPDAFFNEVDKSPTV 488
Query: 526 PAQLMEKYMTT-LLNHPTLFQMNNPLVQISFFELVVRHNNFIQVENKDL-TLLNIFCTPF 583
+Q++ T+ + HP +PLVQ+ + E++VR+ +F E+ + L+ F P
Sbjct: 489 LSQILALVTTSQVCRHP------HPLVQLLYMEILVRYASFFDYESAAIPALIEYFVGPR 542
Query: 584 SMFSGNERVRLRTWYLFTRLIKTSKPKLSTDFXXXXXXXXXXXXXXXXXPL--------- 634
+ + NERVR R WYLF R +K+ K K ++ P+
Sbjct: 543 GIHNTNERVRPRAWYLFYRFVKSIK-KQVVNYTESSLAMLGDLLNISVSPVTDMDAPVPT 601
Query: 635 --AQELDTIFDSQLYLFEGTGVLIGA-NVNNEYEIL--DGVLTPLFADLEQCISAQVKNP 689
+ ++ F+SQLYLFE GVLI + N+ E + L D ++ L +S+ +
Sbjct: 602 LNSSIRNSDFNSQLYLFETVGVLISSGNLTPEEQALYCDSLINALIGKANAALSSDLSAL 661
Query: 690 QVVLQTHHILMAIGTVARGVHSGLVPDNQVNNAKVSERVICKSLIEKFSNIAEVILVTFS 749
+ ++ + LMAIG A+G A+ SE V + + F+ ++ I +
Sbjct: 662 ENIISVYCSLMAIGNFAKGF-----------PARGSEEV---AWLASFNKASDEIFLILD 707
Query: 750 YFNKFETIRDAARFSFSRLIPILNNQIIPFASRLISIFLNSDLKPLEMGDFIGFLGQMIH 809
E IR A RF+ R+I ++ ++P +LISI LNS + E+ D + F+ Q+IH
Sbjct: 708 RMGFNEDIRGAVRFTSGRIINVVGPDMLPKVPQLISILLNS-IDMNELVDVLSFISQLIH 766
Query: 810 MFKDDDNCYQLFNNLFTPVVEKVFXXXXXXXXXXXXXXXXXXXNGKNVIVTDSFREKINL 869
++K DN ++ N + ++ ++F TD ++ +L
Sbjct: 767 IYK--DNMMEITNRMLPTLLMRIFSSLSAAPQG-----------------TDDAVKQNDL 807
Query: 870 KKSYYGLLATFVSNNCTSLLLTESNKNILPRVLTDLLSYTAEEIHETSTMKLSINVLVNF 929
+KSY + ++ S+L TE N+ ++ +L + A + E +T K SI ++
Sbjct: 808 RKSYISFILQLLNKGFGSILFTEENQVYFDPLINSILHF-ANLVGEPATQKSSIALVSKM 866
Query: 930 INFFGTGICTDPKDRNAINVNKLDGLNEF--FITTSIPLLFEIPFKPEYEFNIQDGGCRV 987
++ +G DG+ F F + PL FE+P P FN +DG V
Sbjct: 867 VSLWG----------------GKDGIAGFENFTLSLTPLCFEMPVNP--NFNTRDGQSLV 908
Query: 988 IACDLSRLLKALYXXXXXXXXXXXXXXACVKYLTEIYFPQIQFPQSLVVEFINALGTLDA 1047
+ +L+ L K + YL +YFP + FP + E++ AL LD+
Sbjct: 909 VLGELAGLQKIILEKLGDIYK---------SYLVTVYFPTVNFPDVMASEYLQALSNLDS 959
Query: 1048 KQFEKYFVQFITNMK 1062
+ F+++F +FI +K
Sbjct: 960 RSFKQFFQKFIQALK 974
>Hs8051636 [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1/Exportin-t
(importin beta superfamily)
Length = 962
Score = 235 bits (599), Expect = 3e-61
Identities = 255/1069 (23%), Positives = 450/1069 (41%), Gaps = 142/1069 (13%)
Query: 16 AGNDLKKQALDFLQQLKSSEDAVQVFSQYL-QDPVASDVGRFFALQVLSEQAL----ELP 70
A +D +++AL + +QLK S DA QV ++ L Q + D +FF QVL Q EL
Sbjct: 13 ADSDFRQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHVKFFCFQVLEHQVKYKYSELT 72
Query: 71 ANHEKLYALQQSALQFLRTQLENSSSDGARXXXXXXXXXXXXXTPPEFVRNKVAELFAHL 130
++L ++++ + +L+ Q+ N + F+RNK A++FA L
Sbjct: 73 TVQQQL--IRETLISWLQAQMLNPQPEKT------------------FIRNKAAQVFALL 112
Query: 131 FYNMYGEVNNNMWSSFFVDLIQLVGIASLRDSKSTGVEFNAIGLDLFFRICASINTEIGD 190
F Y W FF D++ +V + N G+DL+ RI +I++E+ D
Sbjct: 113 FVTEY----LTKWPKFFFDILSVV-------------DLNPRGVDLYLRILMAIDSELVD 155
Query: 191 QAFVRSKEVQLKNNELKDYMRVQDVELLSNIWFSALLNCQQL-PVLASLVLQCVGSYISW 249
+ V + E +N +KD MR Q + L W+ L N Q + L+ VG+Y+SW
Sbjct: 156 RDVVHTSEEARRNTLIKDTMREQCIPNLVESWYQILQNYQFTNSEVTCQCLEVVGAYVSW 215
Query: 250 IDINLIVQQSYIGTIYEYLKFPQTKLACGQCLCEIISKKMKPADKLQL---LSMLNLTDR 306
ID++LI +I + ++ + CL E+++K M P DK++L L + +
Sbjct: 216 IDLSLIANDRFINMLLGHMSIEVLREEACDCLFEVVNKGMDPVDKMKLVESLCQVLQSAG 275
Query: 307 VVATGSAEDLDVLEQMAKLTNGVALELSMVMDQCNDSQELQSVSSAADEQIINVVSPLVL 366
+ ED+D L + +KL NG+ L + + + ++++ A Q I L+L
Sbjct: 276 FFSIDQEEDVDFLARFSKLVNGMGQSLIVSWSKLIKNGDIKNAQEAL--QAIETKVALML 333
Query: 367 KFMAHEYDSVTQQCFSFVTNYLAVMKKLFALGGKPGSAVAVNSKRIPIDPAHLNFLKSLG 426
+ + HE D ++ F +YL ++K+L L + ++ ++ L +K
Sbjct: 334 QLLIHEDDDISSNIIGFCYDYLHILKQLTVLS---------DQQKANVEAIMLAVMK--- 381
Query: 427 TVCVLKMKIDDSCDSIDDNEEIDEFVENIRSKLKTFQDSIAVINPELYFDIISDNIEQSI 486
K+ D+ + ++ E+ FVE R +LK D +A ++PEL + ++
Sbjct: 382 -----KLTYDEEYNFENEGEDEAMFVE-YRKQLKLLLDRLAQVSPELLLASVRRVFSSTL 435
Query: 487 TEQQDWRVL--ELAIYQLHNFAESIRNNLFGVNKTEISTSKPAQLMEKYMTTLLNHPTLF 544
Q R + E+AI L+ AE++ + G + + SK + L + T + + + +
Sbjct: 436 QNWQTTRFMEVEVAIRLLYMLAEALPVS-HGAHFSG-DVSKASALQDMMRTLVTSGVSSY 493
Query: 545 QMNNPLVQISFFELVVRHNNFIQVENKDL-TLLNIFCTPFSMFSGNERVRLRTWYLFTRL 603
Q + V + FFE VVR+ F VE + + +L F + + +VR RT YLF+R
Sbjct: 494 QHTS--VTLEFFETVVRYEKFFTVEPQHIPCVLMAFLDHRGLRHSSAKVRSRTAYLFSRF 551
Query: 604 IKTSKPKLSTDFXXXXXXXXXXXXXXXXXPLAQELDTIFDSQLYLFEGTGVLIGANVNNE 663
+K S K F + D QL+++E GVLI VN+E
Sbjct: 552 VK-SLNKQMNPFIEDILNRIQDLLELSPPENGHQSLLSSDDQLFIYETAGVLI---VNSE 607
Query: 664 Y------EILDGVLTPLFAD----LEQCISAQVKNPQVVLQTHHILMAIGTVARGVHSGL 713
Y ++ +LTPL LE+ + AQ + Q L + A+G +R
Sbjct: 608 YPAERKQALMRNLLTPLMEKFKILLEKLMLAQDEERQASL-ADCLNHAVGFASR------ 660
Query: 714 VPDNQVNNAKVSERVICKSLIEKFSNIAEVILVTFSYFNKFETIRDAARFSFSRLIPILN 773
+N + ++ C E + + + L S + + +R R R+I L
Sbjct: 661 -TSKAFSNKQTVKQCGCS---EVYLDCLQTFLPALSCPLQKDILRSGVRTFLHRMIICLE 716
Query: 774 NQIIPFASRLISIFLNSDLKPLEMGDFIGFLGQMIHMFKDDDNCYQLFNNLFTPVVEKVF 833
+++PF S + D + ++ +FI + Q+ FK + + +F P++ +F
Sbjct: 717 EEVLPFIPS-ASEHMLKDCEAKDLQEFIPLINQITAKFKIQVSPF--LQQMFMPLLHAIF 773
Query: 834 XXXXXXXXXXXXXXXXXXXNGKNVIVTDSFREKINLKKSYYGLLATFVSNNCTSLLLTES 893
EK L++SY+ L T + + ++ +
Sbjct: 774 EVLLRPAEENDQSAAL---------------EKQMLRRSYFAFLQTVTGSGMSEVIANQG 818
Query: 894 NKNILPRVLTDLLSYTAEEIHETSTMKLSINVLVNFINFFGTGICTDPKDRNAINVNKLD 953
+N+ RVL ++ A E + K +L + +G KD
Sbjct: 819 AENV-ERVLVTVIQ-GAVEYPDPIAQKTCFIILSKLVELWG------GKDGPV------- 863
Query: 954 GLNEFFITTSIPLLFEIPFKPEYEFNIQDGGCRVIACDLSRLLKALYXXXXXXXXXXXXX 1013
G +F +P F P K F++ D + + + LK ++
Sbjct: 864 GFADFVYKHIVPACFLAPLK--QTFDLADAQTVLALSECAVTLKTIH---------LKRG 912
Query: 1014 XACVKYLTEIYFPQIQFPQSLVVEFINALGTLDAKQFEKYFVQFITNMK 1062
CV+YL + Y P +Q ++ EF AL DAK F+ Y F K
Sbjct: 913 PECVQYLQQEYLPSLQVAPEIIQEFCQALQQPDAKVFKNYLKVFFQRAK 961
>At1g72560 [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1/Exportin-t
(importin beta superfamily)
Length = 993
Score = 170 bits (430), Expect = 1e-41
Identities = 219/964 (22%), Positives = 401/964 (40%), Gaps = 118/964 (12%)
Query: 1 MSHIQQAVDIA-NSSTAGNDLKKQALDFLQQLKSSEDAVQVFSQYLQDPVASDVGRFFAL 59
M ++QA+ I+ + + LK QA+ + QQ+K + + + L V +F+ L
Sbjct: 1 MDDLEQAIVISFETGAVDSALKSQAVTYCQQIKETPSICSICIEKLWFSKLVQV-QFWCL 59
Query: 60 QVLSEQALELPANHEKLYALQQSALQ---FLRTQLENSSSDGARXXXXXXXXXXXXXTPP 116
Q L + L + + +QS ++ F LE ++ A P
Sbjct: 60 QTLQDV---LRVKYGSMSLDEQSYVRKSVFSMACLEVIDNENAGRVVEG----------P 106
Query: 117 EFVRNKVAELFAHLFYNMYGEVNNNMWSSFFVDLIQLVGIASLRDSKSTGVEFNAIGLDL 176
FV+NK+A++ A L Y Y + WSS F+D + L K A+ +D+
Sbjct: 107 PFVKNKLAQVLATLIYYEYPLI----WSSVFLDFM-------LHLCKG------AVVIDM 149
Query: 177 FFRICASINTEIGDQAFVRSKEVQLKNNELKDYMRVQDVELLSNIWFSALLNCQQL-PVL 235
F R+ +++ E+ + R+ E +KD MR Q V ++ W+ + + P L
Sbjct: 150 FCRVLNALDDELISLDYPRTPEEISVAARVKDAMRQQCVPQIARAWYDIVSMYKNSDPDL 209
Query: 236 ASLVLQCVGSYISWIDINLIVQQSYIGTIYEYL----KFPQTKLACGQCLCEIISKKMKP 291
++ VL C+ ++SWIDI L+ +++ ++E + Q + A C+ ++SK+M P
Sbjct: 210 SATVLDCMRRFVSWIDIGLVANDAFVPLLFELILSDGLSEQVRGAAAGCVLAMVSKRMDP 269
Query: 292 ADKLQLLSMLNLTDRVVATGSAEDLDVLEQMAKLTNGVALELSMVMDQCNDSQELQSVSS 351
KL LL L ++ D D++ +++ L G A+E+ + N S++ ++VS
Sbjct: 270 QSKLPLLQTLQISRVFGLVSGDVDSDLVSKVSALLTGYAVEVLECHKRLN-SEDTKAVSM 328
Query: 352 AADEQIINVVSPLVLKFMAH-EYDSVTQQCFSFVTNYLAVMKKLFALGGKP----GSAVA 406
++N V P V M E DS T F+ Y++ +K L AL K +
Sbjct: 329 ----DLLNEVLPSVFYVMQKCEVDS-TFSIVQFLLGYVSTLKGLPALKEKQLLHITQILE 383
Query: 407 VNSKRIPIDPAHLNFLKSLGTVCVLKMKIDDSCDSIDDNEEIDEFVENIRSKLKTFQDSI 466
V +I DP + N L SL +++ + + EF +++ L+T +
Sbjct: 384 VIRIQICYDPMYRNNLNSLDKT------------GLEEEDRMSEFRKDLFVLLRT----V 427
Query: 467 AVINPELYFDIISDNIEQSITEQQDWRV--LELAIYQLHNFAESIRNNLFGVNKTEISTS 524
+ PE+ I +++ ++ + V +E A+ L++F ES+ +S
Sbjct: 428 GRVAPEVTQHFIRNSLANAVESSSESNVEEVEAALSLLYSFGESMTEEAMKTGSGCLSEL 487
Query: 525 KPAQLMEKYMTTLLNHPTLFQMNNPLVQISFFELVVRHNNFIQVENKDL-TLLNIFCTPF 583
P L T H ++ LV + + E + R+ FIQ ++ + +L F
Sbjct: 488 IPMLL----TTQFPGH------SHRLVALVYLENITRYMKFIQENSQYIPNVLGAFLDDR 537
Query: 584 SMFSGNERVRLRTWYLFTRLIKTSKPKLSTDFXXXXXXXXXXXXXXXXXPLAQELDTIFD 643
+ N V R YLF R++K K KL A T +
Sbjct: 538 GLHHQNFYVSRRAGYLFMRVVKLLKSKLVPFIDKILQNLQDTLSQLTTMNFASRELTGTE 597
Query: 644 SQLYLFEGTGVLIGAN---VNNEYEILDGVLTPLFADLEQ-CISAQVKN----PQVVLQT 695
++FE G++IG + + L +LTPL +E + A+V + P +
Sbjct: 598 DGSHIFEAIGIIIGLEDVPAEKQSDYLSLLLTPLCQQIEAGLVQAKVASSEDFPVKIANI 657
Query: 696 HHILMAIGTVARGVHSGLVPDNQVNNAKVSERVICKSLIEKFSNIAEVILVTFSYFNKFE 755
++AI +++G + LV ++ + F +V+L F K E
Sbjct: 658 QFAIVAINALSKGFNERLVTASRPGIGLM------------FKQTLDVLLRVLIEFPKVE 705
Query: 756 TIRDAARFSFSRLIPILNNQIIPFASRLISIFLNSDLKPLEMGDFIGFLGQMIHMFKDDD 815
+R R++ L + + P+ + + L +D +P EM F+ L Q+I
Sbjct: 706 PLRSKVTSFIHRMVDTLGSAVFPYLPKALEQLL-ADSEPKEMVGFMVLLNQLI------- 757
Query: 816 NCYQLFNNLFTPVVEKVFXXXXXXXXXXXXXXXXXXXNGKNVIVTDSFREKINLKKSYYG 875
C FN+ ++E+V+ G VT+ RE I L++ Y
Sbjct: 758 -C--KFNSALHDILEEVYPVVAVRIFNVIPRDGLPSRPG---AVTEEMRELIELQRMLYT 811
Query: 876 LLATFVSNNCTSLLLTESNKNILPRVLTDLLSYTAEEIHETSTMKLSINVLVNF-INFFG 934
L +++ +S+ LT ++ L ++ +L+ + H+ T++ + NF I F
Sbjct: 812 FLHVIATHDLSSVFLTPKSRAYLDPMMQLVLNTSCN--HKDITVR-KVPGFQNFVIEAFA 868
Query: 935 TGIC 938
T C
Sbjct: 869 TNCC 872
>CE27871 [YUJ] KOG2021 Nuclear mRNA export factor receptor LOS1/Exportin-t
(importin beta superfamily)
Length = 1101
Score = 103 bits (257), Expect = 1e-21
Identities = 179/909 (19%), Positives = 349/909 (37%), Gaps = 126/909 (13%)
Query: 12 NSSTAGNDLKKQALDF--LQQLKSSEDA-VQVFSQYLQDPVASDVGRFFALQVLSEQALE 68
N+ A D KQA + L+ LK E + ++ S +F LQV+ +
Sbjct: 7 NAGIAVTDPTKQAEIYRALESLKKDESGWKKSVDSFIGPHKPSPEEQFLLLQVIEDYL-- 64
Query: 69 LPANHEKLYALQQSALQFLRTQLENSSSDGARXXXXXXXXXXXXXTPPEFVRNKVAELFA 128
+++ ++ Q + +RT L + + + P F+ NK+A +F+
Sbjct: 65 ----NKRYHSSSQGDVSVIRTFLLHYTKNSR----------SSTVDQPAFLTNKMAHIFS 110
Query: 129 HLFYNMYGEVNNNMWSSFFVDLIQLVGIASLRDSKSTGVEFNAIGLDLFFRICASINTEI 188
+F + E WSSFF DL I D K V F + ++ +I+TE+
Sbjct: 111 LVFAADFPE----RWSSFFNDLFFSDNI---NDRK---VAF------FYLKVLLAIDTEV 154
Query: 189 GDQAFVRSKEVQLKNNELKDYMRVQDVELLSNIWFSALLNCQQLPVLASLVLQCVGSYIS 248
++ RSK +N ++KD MR + ++ W + + V+ LVL + SY+
Sbjct: 155 VNRDIQRSKNESDRNIKIKDAMREICINEIAKSWLTIANALPEDNVIQCLVLDNIASYVD 214
Query: 249 WIDINLIVQQSYIGTIYEYLKFPQTKLACGQCLCEIISKKMKPADKLQLLSMLNLT---- 304
WI+++L+ + I + P T + +C ++ K M PA+K L++ +T
Sbjct: 215 WIELDLVANDYVMPLIISKFQNPATSESATAAVCSLLEKGM-PAEKKVGLTLTIMTVLRS 273
Query: 305 DRVVATGSAEDLDVLEQMAKLTNGVALELSMVMDQCNDSQELQSVSSAADEQIINVVSPL 364
+ ++ D + + ++ L N + L L V ++ S L+ +++ + P
Sbjct: 274 NGLLTVNDNNDEEEVTRVGSLVNTLGLVLLDVQNKLCASSILEKEQECCVQEMAGLAEP- 332
Query: 365 VLKFMAHEYDSVTQQCFSFVTNYLAVMKKLFALGGKPGSAVAVNSKRIPIDPAHLNFLKS 424
L + +E ++ C ++ Y + + K P NF++
Sbjct: 333 ALVVLNNEDPDLSCMCIDYIRAYCSFLLK--------------------FHPNETNFIEK 372
Query: 425 LGTVCVLKMKIDDSCDSIDDNEEIDEFVENIRSKLKTFQDSIAVINPELYFDIISDNIEQ 484
+ + + ++D D E+ EF E R +L++ + I + PE + + +
Sbjct: 373 VIRAGLQRYVMNDDMTVGGDGEDEVEFQE-FRRELRSMLNVIGLKRPEAIINAVEPWTAE 431
Query: 485 SITEQQDWRV--LELAIYQLHNFAESIRNNLFGVNKTEISTSKPAQLMEKYMTTLLNHPT 542
+ V +E + + + E I +N+ + IS + A+L ++
Sbjct: 432 VTSGGSSIPVNRIEALLNVIFHLHEIIPSNMLQSPREGIS-QRAARL-----PIVILEGL 485
Query: 543 LFQMNNPLVQISFFELVVRHNNFIQVENKDLTLLNI---FCTPFSMFSGNERVRLRTWYL 599
+ P + + +FEL R+ + ++ + + + +I F + + VR R YL
Sbjct: 486 VLDGRCPAIHVLYFELACRYERLLVLQPQPVVIPHIAAAFLDQRGISISSANVRTRIVYL 545
Query: 600 FTRLIKTSKPKLSTDFXXXXXXXXXXXXXXXXXPLAQELDTIFDSQLYLFEGTGVLIGAN 659
F R +K+ K L Q L + Q Y+FE T LI
Sbjct: 546 FCRFVKSHKTVLGPLVSEVITRLAPLLAVSPQADTNQLLSP--EDQGYIFEATATLI--- 600
Query: 660 VNNEYEILDGVLTPLFADLEQCISAQVKNPQVVLQTHHILMAIGTVARGVHSGLVPDNQV 719
+F DL + +Q ++ T+A +GLV N
Sbjct: 601 --------------VFGDLTSEMKSQ-----------YVGELASTLAMKFENGLVELNTA 635
Query: 720 NNAKVSERVICKSLIEKFSNIAEVILVTFSYFNKFETIRDAARFS-FSRLIPILNNQIIP 778
K E I +++++ SNI FN ++++ + RLI + + P
Sbjct: 636 RARKADEETI-QAILQFMSNIIGYSSRMSKAFNNAQSMKACNCIDIYLRLIKLYLETLSP 694
Query: 779 -----------FASRLISIFLNSDLKPLEMGDFIGFLGQMIHMFKDDDNCYQLF---NNL 824
FA RL+ + + ++L P G F ++ + D D+ + L +
Sbjct: 695 QNAFLLESTRQFAHRLV-VSMENELMPYMNGIF----DKLALVSTDLDSMHHLLIFCHQT 749
Query: 825 FTPVVEKVFXXXXXXXXXXXXXXXXXXXNGKNVIVT--DSFREKINLKKSYYGLLATFVS 882
+ + +N I DS R + +++++ LL T ++
Sbjct: 750 VAKYKKAMLTSGVDLGNVLAIAARASLQEQENNIPAKDDSQRALLYVQRAFVQLLYTVIA 809
Query: 883 NNCTSLLLT 891
++CT L T
Sbjct: 810 SDCTPALNT 818
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.137 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,049,188
Number of Sequences: 60738
Number of extensions: 2160081
Number of successful extensions: 5773
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 5721
Number of HSP's gapped (non-prelim): 7
length of query: 1063
length of database: 30,389,216
effective HSP length: 117
effective length of query: 946
effective length of database: 23,282,870
effective search space: 22025595020
effective search space used: 22025595020
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)